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TDMS Study 05704-01 Pathology Tables

NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97
Route: GAVAGE                                                                                                     Time: 08:24:54




       Facility:  International Research and Development Corp.

       Chemical CAS #:  108-46-3

       Lock Date:  None

       Cage Range:  All

       Reasons For Removal:    All

       Removal Date Range:     All

       Treatment Groups:       Include All






































                                                              Page   1

NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 7| 7| 4| 6| 7| 7| 7| 7| 7| 7| 7| 6| 4| 5| 7| 7| 7| 4| 7| 7| 7| 7|             
                             DAY ON TEST   | 5| 3| 3| 3| 3| 5| 2| 3| 3| 3| 3| 3| 3| 2| 1| 5| 0| 3| 3| 3| 5| 3| 3| 3| 3|             
                                           | 6| 4| 4| 3| 4| 6| 0| 5| 0| 5| 3| 1| 5| 7| 7| 6| 0| 3| 0| 5| 6| 0| 5| 3| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    CONTROL                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
    F                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Inflammation, Subacute               |                                                                          |             
      Perforation                          |                                                                          |             
                                            __________________________________________________________________________|             
   Gallbladder                             |    +  +  +  +     A  +  +  +  +  +  +  A  +     +  +  +  +     +  +  +  +|             
      Serosa, Inflammation, Acute          |                                                 3                        |             
                                            __________________________________________________________________________|             
   Intestine Large                         |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |    +  +  +  +     +  +  +  +  +  +  +  A  +     +  +  +  +     +  +  +  +|             
      Parasite Metazoan                    |                                                       X                  |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                        2                                 |             
      Parasite Metazoan                    |                                                                          |             
      Serosa, Inflammation, Acute          |                                                 2                        |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small                         |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               |    +  +  +  +     +  +  +  +  +  +  +  A  +     +  +  +  +     +  +  +  +|             
      Serosa, Inflammation, Acute          |                                                 2                        |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  |    +  +  +  +     A  +  +  +  +  A  +  A  A     +  +  +  +     +  +  +  +|             
      Hyperplasia, Focal, Lymphoid         |                                                                          |             
      Serosa, Inflammation, Acute          |                                                 2                        |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                |    +  +  +  +     +  +  +  +  +  A  +  A  +     +  +  +  +     +  +  +  +|             
      Hyperplasia, Focal, Lymphoid         |                                                                          |             
      Serosa, Inflammation, Acute          |                                                 2                        |             
                                            __________________________________________________________________________|             
   Liver                                   |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Multifocal                      |       1                                            1                     |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |             2     1                       2              1        1  1   |             
      Necrosis, Acute, Focal               |                                                                          |             
      Necrosis, Focal, Subacute            |                                                          1               |             
      Vacuolization Cytoplasmic, Focal     |                                                                   1      |             
      Centrilobular, Fatty Change          |                                                                          |             
      Periportal, Fatty Change             |                   2                                                      |             
      Serosa, Inflammation, Subacute       |                                                 4                        |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                                          |             
      Fat, Necrosis                        |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                |    +  +  +  +     +  +  +  +  +  +  +  A  +     +  +  +  +     +  +  +  +|             
      Atrophy, Diffuse                     |                                                                          |             
      Cyst                                 |          X                                         X                     |             
      Hyperplasia, Focal, Glandular        |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                                                          |             
      Inflammation, Acute                  |                                                 3  2                     |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |    +  +  +  +     +  +  +  +  +  +  +  M  +     +  +  +  +     +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page   2                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 7| 7| 4| 6| 7| 7| 7| 7| 7| 7| 7| 6| 4| 5| 7| 7| 7| 4| 7| 7| 7| 7|             
                             DAY ON TEST   | 5| 3| 3| 3| 3| 5| 2| 3| 3| 3| 3| 3| 3| 2| 1| 5| 0| 3| 3| 3| 5| 3| 3| 3| 3|             
                                           | 6| 4| 4| 3| 4| 6| 0| 5| 0| 5| 3| 1| 5| 7| 7| 6| 0| 3| 0| 5| 6| 0| 5| 3| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    CONTROL                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
    F                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                         1                                                |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                            2                                         2  2|             
      Infiltration Cellular, Multifocal,   |                                                                          |             
           Plasma Cell                     |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    |    +  +  +  +     +  +  +  +  +  +  +  I  +     +  +  +  +     +  +  +  +|             
      Hyperplasia, Focal, Squamous         |                            2                                             |             
      Hyperplasia, Multifocal              |                                                                          |             
      Hyperplasia, Multifocal, Squamous    |          2                                               3               |             
      Inflammation, Chronic                |                                                          2               |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Cyst                                 |                                                                          |             
      Erosion, Multifocal                  |                                  2                                       |             
      Serosa, Inflammation, Chronic        |                                                    3                     |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                  +                                       |             
      Inflammation, Chronic                |                                  2                                       |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Coronary Artery, Hyperplasia,        |                                                                          |             
          Chronic, Multifocal              |                                                       2                  |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |    +  +  +  +     +     +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Congestion, Focal                    |                                                                          |             
      Inflammation, Subacute               |                                                 2                        |             
      Vacuolization Cytoplasmic, Focal     |       2                                                                  |             
      Vacuolization Cytoplasmic, Multifocal|                                                                          |             
      Spindle Cell, Hyperplasia            |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  |    +  +  +  +     +     +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |    +  +  +  +     +  +  +  +  +  +  +  A  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       |    M  M  +  M     +  +  M  M  +  +  +  M  +     M  M  M  I     M  +  +  M|             
      Infiltration Cellular, Focal, Plasma |                                                                          |             
          Cell                             |                                                                          |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         |    +  +  +  +     +  +  +  +  +  +  +  M  +     +  +  +  +     +  +  +  +|             
      Pars Distalis, Ectasia, Focal        |                                                                          |             
      Pars Distalis, Hyperplasia, Focal    |             2        3     2                                   2     2   |             
      Pars Distalis, Hyperplasia,          |                                                                          |             
          Multifocal                       |                               3                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           |    +  +  +  +     +  +  +  +  +  +  +  M  +     +  +  +  +     +  +  +  +|             
      Depletion Secretory                  |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   3                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 7| 7| 4| 6| 7| 7| 7| 7| 7| 7| 7| 6| 4| 5| 7| 7| 7| 4| 7| 7| 7| 7|             
                             DAY ON TEST   | 5| 3| 3| 3| 3| 5| 2| 3| 3| 3| 3| 3| 3| 2| 1| 5| 0| 3| 3| 3| 5| 3| 3| 3| 3|             
                                           | 6| 4| 4| 3| 4| 6| 0| 5| 0| 5| 3| 1| 5| 7| 7| 6| 0| 3| 0| 5| 6| 0| 5| 3| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    CONTROL                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
    F                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
      Follicular Cell, Hyperplasia         |                            2                                   4         |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Abscess                              |                                                 4  4                     |             
      Cyst                                 |                                  X                             X        X|             
      Cyst Multilocular                    |          X  X           X                                                |             
      Hemorrhage                           |                      3                                   3               |             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |       3                                                                  |             
                                            __________________________________________________________________________|             
   Uterus                                  |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Abscess                              |                                                 4                        |             
      Dilatation                           |                   2                    4                                 |             
      Hyperplasia, Chronic, Cystic, Diffuse|    2  4  3  3        3  4  3  4     3     2     3  3  2  4     3     4  4|             
      Hyperplasia, Diffuse, Lymphoid       |                                                                          |             
      Serosa, Inflammation, Acute          |                                                 2                        |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Myelofibrosis                        |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Axillary, Infiltration Cellular,     |                                                                          |             
           Diffuse, Plasma Cell            |                                                                          |             
      Iliac, Hematopoietic Cell            |                                                                          |             
          Proliferation, Diffuse           |                                                    3                     |             
      Iliac, Hyperplasia, Diffuse, Lymphoid|                                           2        4                     |             
      Mediastinal, Infiltration Cellular,  |                                                                          |             
           Diffuse, Plasma Cell            |                                                                          |             
      Renal, Hyperplasia, Diffuse, Lymphoid|                                           3                              |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |    +  +  +  +     +  +  +  +  +  +  +  +  +     +     M  +     +  +  +  +|             
      Giant Cell, Diffuse                  |                                                          2               |             
      Hyperplasia, Lymphoid                |                                                                          |             
      Infiltration Cellular, Diffuse,      |                                                                          |             
          Histiocyte                       |                                           2                              |             
                                            __________________________________________________________________________|             
   Spleen                                  |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |          4                                         4  4                  |             
      Hyperplasia, Diffuse, Lymphoid       |                                                    4                     |             
      Hyperplasia, Lymphoid                |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   4                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 7| 7| 4| 6| 7| 7| 7| 7| 7| 7| 7| 6| 4| 5| 7| 7| 7| 4| 7| 7| 7| 7|             
                             DAY ON TEST   | 5| 3| 3| 3| 3| 5| 2| 3| 3| 3| 3| 3| 3| 2| 1| 5| 0| 3| 3| 3| 5| 3| 3| 3| 3|             
                                           | 6| 4| 4| 3| 4| 6| 0| 5| 0| 5| 3| 1| 5| 7| 7| 6| 0| 3| 0| 5| 6| 0| 5| 3| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    CONTROL                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
    F                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Capsule, Inflammation, Acute         |                                                 3                        |             
                                            __________________________________________________________________________|             
   Thymus                                  |    +  +  +  +     M  +  +  +  +  +  +  +  +     M  +  M  +     I  +  +  +|             
      Medulla, Hyperplasia, Focal, Lymphoid|                         3  3                             2           3   |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Skin                                    |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Inflammation, Chronic                |                                                       1                  |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Hyperostosis                         |                                                                          |             
      Osteoporosis                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   |    +  +  +  +     +  +  +  +  +  +  +  M  +     +  +  +  +     +  +  +  +|             
      Hemorrhage, Multifocal               |             2                                                            |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                                                          |             
      Mineralization, Multifocal           |    2     2  2           1     2           1              2     1     1   |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Congestion, Diffuse                  |                                                                          |             
      Hyperplasia, Focal, Adenomatous      |                                                                   2      |             
      Infiltration Cellular, Diffuse,      |                                                                          |             
          Histiocyte                       |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |    3  3     3        2  1                 2        2     2     1  1  2  1|             
      Mediastinum, Bacterium               |                                                                          |             
      Mediastinum, Inflammation, Chronic,  |                                                                          |             
           Multifocal                      |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Foreign Body                         |                                                       1                  |             
      Inflammation, Acute                  |                                                       2        1         |             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
           Chronic                         |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                                                 +        M        +      |             
      Degeneration, Chronic, Diffuse       |                                                                   4      |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   5                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 7| 7| 4| 6| 7| 7| 7| 7| 7| 7| 7| 6| 4| 5| 7| 7| 7| 4| 7| 7| 7| 7|             
                             DAY ON TEST   | 5| 3| 3| 3| 3| 5| 2| 3| 3| 3| 3| 3| 3| 2| 1| 5| 0| 3| 3| 3| 5| 3| 3| 3| 3|             
                                           | 6| 4| 4| 3| 4| 6| 0| 5| 0| 5| 3| 1| 5| 7| 7| 6| 0| 3| 0| 5| 6| 0| 5| 3| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    CONTROL                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
    F                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |    2  2     2     1  2  2     1           4     2  1  1  1     2        2|             
      Glomerulus, Amyloid Deposition,      |                                                                          |             
          Diffuse                          |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         |    +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                         2                          2     2              2|             
      Serosa, Inflammation, Acute          |                                                 2                        |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   6                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 3| 4| 7| 7| 7| 4| 7| 7| 7| 7| 4| 6| 7| 7| 7| 1| 7| 7| 7| 7| 4| 7| 6| 7| 7|             
                             DAY ON TEST   | 9| 5| 3| 3| 3| 5| 3| 3| 3| 3| 5| 3| 3| 3| 3| 2| 3| 3| 3| 3| 5| 3| 7| 3| 1|             
                                           | 3| 6| 3| 3| 0| 6| 5| 0| 4| 0| 6| 9| 3| 4| 5| 7| 3| 4| 0| 3| 6| 4| 2| 4| 5|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    CONTROL                                | 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|             
    F                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Inflammation, Subacute               | 4                                                                        |             
      Perforation                          | X                                                                        |             
                                            __________________________________________________________________________|             
   Gallbladder                             | A     +  +  +     +  +  +  +     +  +  +  +  A  +  +  +  +     +  +  +  +|             
      Serosa, Inflammation, Acute          |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large                         | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Parasite Metazoan                    |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                                                          |             
      Parasite Metazoan                    |                                                                          |             
      Serosa, Inflammation, Acute          |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small                         | A     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | A     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Serosa, Inflammation, Acute          |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | A     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Hyperplasia, Focal, Lymphoid         |             3                                                            |             
      Serosa, Inflammation, Acute          |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | A     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Hyperplasia, Focal, Lymphoid         |             3                                                            |             
      Serosa, Inflammation, Acute          |                                                                          |             
                                            __________________________________________________________________________|             
   Liver                                   | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Multifocal                      |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |          2        1     1                                                |             
      Necrosis, Acute, Focal               |                                                                          |             
      Necrosis, Focal, Subacute            |                                                                          |             
      Vacuolization Cytoplasmic, Focal     |                                                                          |             
      Centrilobular, Fatty Change          |                                                                   3      |             
      Periportal, Fatty Change             |                                                                          |             
      Serosa, Inflammation, Subacute       |                                                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                     +                                    |             
      Fat, Necrosis                        |                                     3                                    |             
                                            __________________________________________________________________________|             
   Pancreas                                | A     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Atrophy, Diffuse                     |                                                                          |             
      Cyst                                 |                                                                          |             
      Hyperplasia, Focal, Glandular        |                                                                   2      |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                  2                                       |             
      Inflammation, Acute                  |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page   7                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 3| 4| 7| 7| 7| 4| 7| 7| 7| 7| 4| 6| 7| 7| 7| 1| 7| 7| 7| 7| 4| 7| 6| 7| 7|             
                             DAY ON TEST   | 9| 5| 3| 3| 3| 5| 3| 3| 3| 3| 5| 3| 3| 3| 3| 2| 3| 3| 3| 3| 5| 3| 7| 3| 1|             
                                           | 3| 6| 3| 3| 0| 6| 5| 0| 4| 0| 6| 9| 3| 4| 5| 7| 3| 4| 0| 3| 6| 4| 2| 4| 5|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    CONTROL                                | 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|             
    F                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                           1                              |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |       1  2  2        1  2                             2  2           2  2|             
      Infiltration Cellular, Multifocal,   |                                                                          |             
           Plasma Cell                     |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Hyperplasia, Focal, Squamous         |                                                                          |             
      Hyperplasia, Multifocal              |          3                                                               |             
      Hyperplasia, Multifocal, Squamous    |                                                                          |             
      Inflammation, Chronic                |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Cyst                                 |             X                                                            |             
      Erosion, Multifocal                  |                                                                          |             
      Serosa, Inflammation, Chronic        |                                                                          |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                                                          |             
      Inflammation, Chronic                |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Coronary Artery, Hyperplasia,        |                                                                          |             
          Chronic, Multifocal              |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +     +  +  +     +  +  +  +     I  +  +  +  +  +  +  +  +     +  +     +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +     +|             
      Congestion, Focal                    |                                        2                                 |             
      Inflammation, Subacute               |                                                                          |             
      Vacuolization Cytoplasmic, Focal     |                                                                          |             
      Vacuolization Cytoplasmic, Multifocal|                   2                                      2               |             
      Spindle Cell, Hyperplasia            |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +     +  +  +     +  +  +  +     M  +  +  +  +  +  +  +  +     +  +     +|             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | A     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | M     M  M  +     M  +  +  +     M  +  M  +  +  M  +  M  +     +  +  M  +|             
      Infiltration Cellular, Focal, Plasma |                                                                          |             
          Cell                             |                                              2                           |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Pars Distalis, Ectasia, Focal        |          3                                                               |             
      Pars Distalis, Hyperplasia, Focal    |       2  2           3                          2                        |             
      Pars Distalis, Hyperplasia,          |                                                                          |             
          Multifocal                       |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Depletion Secretory                  | 4                                                                        |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   8                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 3| 4| 7| 7| 7| 4| 7| 7| 7| 7| 4| 6| 7| 7| 7| 1| 7| 7| 7| 7| 4| 7| 6| 7| 7|             
                             DAY ON TEST   | 9| 5| 3| 3| 3| 5| 3| 3| 3| 3| 5| 3| 3| 3| 3| 2| 3| 3| 3| 3| 5| 3| 7| 3| 1|             
                                           | 3| 6| 3| 3| 0| 6| 5| 0| 4| 0| 6| 9| 3| 4| 5| 7| 3| 4| 0| 3| 6| 4| 2| 4| 5|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    CONTROL                                | 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|             
    F                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
      Follicular Cell, Hyperplasia         |                            2           2                 2               |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  I  +     +  +  +  +|             
      Abscess                              |                                                                          |             
      Cyst                                 |                                                                          |             
      Cyst Multilocular                    |          X              X                 X                              |             
      Hemorrhage                           |                                        4                                 |             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                          2               |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                                                          |             
                                            __________________________________________________________________________|             
   Uterus                                  | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Abscess                              |                                                                          |             
      Dilatation                           |                                                                          |             
      Hyperplasia, Chronic, Cystic, Diffuse|       4  3  4     3  4     3        4     4     4  3  2  3     4  3  3  4|             
      Hyperplasia, Diffuse, Lymphoid       |                         3                                                |             
      Serosa, Inflammation, Acute          |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Myelofibrosis                        |                                                 2              2         |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Axillary, Infiltration Cellular,     |                                                                          |             
           Diffuse, Plasma Cell            |                                                                          |             
      Iliac, Hematopoietic Cell            |                                                                          |             
          Proliferation, Diffuse           |                                                                          |             
      Iliac, Hyperplasia, Diffuse, Lymphoid|                                                                          |             
      Mediastinal, Infiltration Cellular,  |                                                                          |             
           Diffuse, Plasma Cell            |                                              3                           |             
      Renal, Hyperplasia, Diffuse, Lymphoid|                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Giant Cell, Diffuse                  |                                                                          |             
      Hyperplasia, Lymphoid                |                                                          3               |             
      Infiltration Cellular, Diffuse,      |                                                                          |             
          Histiocyte                       |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |                   2                                                      |             
      Hyperplasia, Diffuse, Lymphoid       |                                                                          |             
      Hyperplasia, Lymphoid                |                                                          3               |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   9                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 3| 4| 7| 7| 7| 4| 7| 7| 7| 7| 4| 6| 7| 7| 7| 1| 7| 7| 7| 7| 4| 7| 6| 7| 7|             
                             DAY ON TEST   | 9| 5| 3| 3| 3| 5| 3| 3| 3| 3| 5| 3| 3| 3| 3| 2| 3| 3| 3| 3| 5| 3| 7| 3| 1|             
                                           | 3| 6| 3| 3| 0| 6| 5| 0| 4| 0| 6| 9| 3| 4| 5| 7| 3| 4| 0| 3| 6| 4| 2| 4| 5|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    CONTROL                                | 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|             
    F                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Capsule, Inflammation, Acute         |                                                                          |             
                                            __________________________________________________________________________|             
   Thymus                                  | M     +  +  +     +  +  +  +     +  +  M  +  +  +  +  M  +     +  +  +  +|             
      Medulla, Hyperplasia, Focal, Lymphoid|             3                             3                              |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Skin                                    | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Inflammation, Chronic                |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Hyperostosis                         |                                                 X              3         |             
      Osteoporosis                         |                      4                                                   |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Hemorrhage, Multifocal               |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                                          2               |             
      Mineralization, Multifocal           |                   2  1     2              1     1  1              1  1   |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Congestion, Diffuse                  | 3                                                                        |             
      Hyperplasia, Focal, Adenomatous      |                                                                          |             
      Infiltration Cellular, Diffuse,      |                                                                          |             
          Histiocyte                       |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 | 1     2  2  2     1  1  2  1        2  1  2     2  1     2     2     3   |             
      Mediastinum, Bacterium               |                                              X                           |             
      Mediastinum, Inflammation, Chronic,  |                                                                          |             
           Multifocal                      |                                              4                           |             
                                            __________________________________________________________________________|             
   Nose                                    | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Foreign Body                         |                                  1                                       |             
      Inflammation, Acute                  |                                  1                                       |             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
           Chronic                         |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                                                                          |             
      Degeneration, Chronic, Diffuse       |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  10                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 3| 4| 7| 7| 7| 4| 7| 7| 7| 7| 4| 6| 7| 7| 7| 1| 7| 7| 7| 7| 4| 7| 6| 7| 7|             
                             DAY ON TEST   | 9| 5| 3| 3| 3| 5| 3| 3| 3| 3| 5| 3| 3| 3| 3| 2| 3| 3| 3| 3| 5| 3| 7| 3| 1|             
                                           | 3| 6| 3| 3| 0| 6| 5| 0| 4| 0| 6| 9| 3| 4| 5| 7| 3| 4| 0| 3| 6| 4| 2| 4| 5|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    CONTROL                                | 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|             
    F                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 | 2                                                                        |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |       1  2        1     2  1        2  1  1  1  3  1  2  2     2     2   |             
      Glomerulus, Amyloid Deposition,      |                                                                          |             
          Diffuse                          |                         2                                                |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | A     +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                  3                                       |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                                          2               |             
      Serosa, Inflammation, Acute          |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  11                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 4| 7| 7| 6| 7| 4| 6| 7| 7| 6|                                            |            |
                             DAY ON TEST   | 5| 3| 3| 2| 3| 5| 2| 3| 3| 9|                                            |            |
                                           | 6| 5| 0| 5| 5| 6| 2| 0| 4| 7|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|                                            |      A     |
    CONTROL                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|                                            |      L     |
    F                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               |    +  +  +  +     +  +  +  +                                             |  50        |
      Inflammation, Subacute               |                                                                          |      1  4.0|
      Perforation                          |                                                                          |      1     |
                                            __________________________________________________________________________|____________|
   Gallbladder                             |    +  +  A  +     A  +  +  A                                             |  43        |
      Serosa, Inflammation, Acute          |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Intestine Large                         |    +  +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  |    +  +  +  +     M  +  +  +                                             |  48        |
      Parasite Metazoan                    |                                                                          |      1     |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  |    +  +  +  +     +  +  +  +                                             |  50        |
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |                                                                          |      1  2.0|
      Parasite Metazoan                    |                         X                                                |      1     |
      Serosa, Inflammation, Acute          |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 |    +  +  +  +     M  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Small                         |    +  +  +  +     +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               |    +  +  A  +     +  +  +  +                                             |  47        |
      Serosa, Inflammation, Acute          |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  |    +  +  +  +     +  +  +  A                                             |  44        |
      Hyperplasia, Focal, Lymphoid         |                                                                          |      1  3.0|
      Serosa, Inflammation, Acute          |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                |    +  +  +  +     +  +  +  +                                             |  47        |
      Hyperplasia, Focal, Lymphoid         |                                                                          |      1  3.0|
      Serosa, Inflammation, Acute          |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Liver                                   |    +  +  +  +     +  +  +  +                                             |  50        |
      Hematopoietic Cell Proliferation,    |                                                                          |            |
           Multifocal                      |                                                                          |      2  1.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |          3           1  1  4                                             |     13  1.6|
      Necrosis, Acute, Focal               |                      3                                                   |      1  3.0|
      Necrosis, Focal, Subacute            |                                                                          |      1  1.0|
      Vacuolization Cytoplasmic, Focal     |                                                                          |      1  1.0|
      Centrilobular, Fatty Change          |          2                                                               |      2  2.5|
      Periportal, Fatty Change             |                                                                          |      1  2.0|
      Serosa, Inflammation, Subacute       |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Mesentery                               |                                                                          |   1        |
      Fat, Necrosis                        |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Pancreas                                |    +  +  +  +     +  +  +  +                                             |  48        |
      Atrophy, Diffuse                     |                   4                                                      |      1  4.0|
      Cyst                                 |                                                                          |      2     |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  12                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 4| 7| 7| 6| 7| 4| 6| 7| 7| 6|                                            |            |
                             DAY ON TEST   | 5| 3| 3| 2| 3| 5| 2| 3| 3| 9|                                            |            |
                                           | 6| 5| 0| 5| 5| 6| 2| 0| 4| 7|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|                                            |      A     |
    CONTROL                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|                                            |      L     |
    F                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
      Hyperplasia, Focal, Glandular        |       1                                                                  |      2  1.5|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |                                                                          |      1  2.0|
      Inflammation, Acute                  |                                                                          |      2  2.5|
                                            __________________________________________________________________________|____________|
   Salivary Glands                         |    +  +  +  +     M  +  +  +                                             |  48        |
      Infiltration Cellular, Focal,        |                                                                          |            |
          Mononuclear Cell                 |       1                 1                                                |      4  1.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |             1                                                            |     13  1.8|
      Infiltration Cellular, Multifocal,   |                                                                          |            |
           Plasma Cell                     |                            2                                             |      1  2.0|
                                            __________________________________________________________________________|____________|
   Stomach                                 |    +  +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    |    +  +  +  +     +  +  +  +                                             |  49        |
      Hyperplasia, Focal, Squamous         |                                                                          |      1  2.0|
      Hyperplasia, Multifocal              |                                                                          |      1  3.0|
      Hyperplasia, Multifocal, Squamous    |                                                                          |      2  2.5|
      Inflammation, Chronic                |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      |    +  +  +  +     +  +  +  +                                             |  50        |
      Cyst                                 |                                                                          |      1     |
      Erosion, Multifocal                  |                                                                          |      1  2.0|
      Serosa, Inflammation, Chronic        |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Tooth                                   |                                                                          |   1        |
      Inflammation, Chronic                |                                                                          |      1  2.0|
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Heart                                   |    +  +  +  +     +  +  +  +                                             |  50        |
      Coronary Artery, Hyperplasia,        |                                                                          |            |
          Chronic, Multifocal              |                                                                          |      1  2.0|
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           |    +  +  +  +     +  +  +  +                                             |  48        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   |    +  +  +  +     +  +  +  +                                             |  48        |
      Congestion, Focal                    |                                                                          |      1  2.0|
      Inflammation, Subacute               |                                                                          |      1  2.0|
      Vacuolization Cytoplasmic, Focal     |                                                                          |      1  2.0|
      Vacuolization Cytoplasmic, Multifocal|                                                                          |      2  2.0|
      Spindle Cell, Hyperplasia            |                   3                                                      |      1  3.0|
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  |    +  +  +  +     +  +  +  +                                             |  47        |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      |    +  +  +  +     +  +  +  +                                             |  48        |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  13                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 4| 7| 7| 6| 7| 4| 6| 7| 7| 6|                                            |            |
                             DAY ON TEST   | 5| 3| 3| 2| 3| 5| 2| 3| 3| 9|                                            |            |
                                           | 6| 5| 0| 5| 5| 6| 2| 0| 4| 7|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|                                            |      A     |
    CONTROL                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|                                            |      L     |
    F                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       |    I  M  +  M     M  +  +  M                                             |  24        |
      Infiltration Cellular, Focal, Plasma |                                                                          |            |
          Cell                             |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         |    +  +  +  M     +  +  +  +                                             |  48        |
      Pars Distalis, Ectasia, Focal        |                                                                          |      1  3.0|
      Pars Distalis, Hyperplasia, Focal    |                                                                          |      9  2.2|
      Pars Distalis, Hyperplasia,          |                                                                          |            |
          Multifocal                       |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           |    +  +  +  +     +  +  +  +                                             |  49        |
      Depletion Secretory                  |                                                                          |      1  4.0|
      Follicular Cell, Hyperplasia         |                                                                          |      5  2.4|
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Ovary                                   |    +  +  +  +     +  +  +  +                                             |  49        |
      Abscess                              |                                                                          |      2  4.0|
      Cyst                                 |                                                                          |      3     |
      Cyst Multilocular                    |                                                                          |      6     |
      Hemorrhage                           |                                                                          |      3  3.3|
      Infiltration Cellular, Focal,        |                                                                          |            |
          Mononuclear Cell                 |                                                                          |      1  2.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |                            3                                             |      2  3.0|
                                            __________________________________________________________________________|____________|
   Uterus                                  |    +  +  +  +     +  +  +  +                                             |  50        |
      Abscess                              |                                                                          |      1  4.0|
      Dilatation                           |                                                                          |      2  3.0|
      Hyperplasia, Chronic, Cystic, Diffuse|    3  4  2  4     3  2  4  2                                             |     41  3.2|
      Hyperplasia, Diffuse, Lymphoid       |                                                                          |      1  3.0|
      Serosa, Inflammation, Acute          |                                                                          |      1  2.0|
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             |    +  +  +  +     +  +  +  +                                             |  50        |
      Myelofibrosis                        |                                                                          |      2  2.0|
                                            __________________________________________________________________________|____________|
   Lymph Node                              |    +  +  +  +     +  +  +  +                                             |  50        |
      Axillary, Infiltration Cellular,     |                                                                          |            |
           Diffuse, Plasma Cell            |                            2                                             |      1  2.0|
      Iliac, Hematopoietic Cell            |                                                                          |            |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  14                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 4| 7| 7| 6| 7| 4| 6| 7| 7| 6|                                            |            |
                             DAY ON TEST   | 5| 3| 3| 2| 3| 5| 2| 3| 3| 9|                                            |            |
                                           | 6| 5| 0| 5| 5| 6| 2| 0| 4| 7|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|                                            |      A     |
    CONTROL                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|                                            |      L     |
    F                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
          Proliferation, Diffuse           |                                                                          |      1  3.0|
      Iliac, Hyperplasia, Diffuse, Lymphoid|                                                                          |      2  3.0|
      Mediastinal, Infiltration Cellular,  |                                                                          |            |
           Diffuse, Plasma Cell            |                                                                          |      1  3.0|
      Renal, Hyperplasia, Diffuse, Lymphoid|                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  |    +  +     +     +  +  +  +                                             |  47        |
      Giant Cell, Diffuse                  |                                                                          |      1  2.0|
      Hyperplasia, Lymphoid                |                                                                          |      1  3.0|
      Infiltration Cellular, Diffuse,      |                                                                          |            |
          Histiocyte                       |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Spleen                                  |    +  +  +  +     +  +  +  +                                             |  50        |
      Hematopoietic Cell Proliferation,    |                                                                          |            |
           Diffuse                         |                            4                                             |      5  3.6|
      Hyperplasia, Diffuse, Lymphoid       |                                                                          |      1  4.0|
      Hyperplasia, Lymphoid                |                                                                          |      1  3.0|
      Capsule, Inflammation, Acute         |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Thymus                                  |    +  +  +  +     +  +  +  +                                             |  43        |
      Medulla, Hyperplasia, Focal, Lymphoid|                                                                          |      6  2.8|
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           |    +  +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Skin                                    |    +  +  +  I     +  +  +  +                                             |  49        |
      Inflammation, Chronic                |                                                                          |      1  1.0|
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    |    +  +  +  +     +  +  +  +                                             |  50        |
      Hyperostosis                         |                                                                          |      2  3.0|
      Osteoporosis                         |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   |    +  +  +  +     +  +  +  +                                             |  49        |
      Hemorrhage, Multifocal               |                                                                          |      1  2.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |                                                                          |      1  2.0|
      Mineralization, Multifocal           |    1                 2  1  1                                             |     21  1.4|
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    |    +  +  +  +     +  +  +  +                                             |  50        |
      Congestion, Diffuse                  |                                                                          |      1  3.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  15                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 4| 7| 7| 6| 7| 4| 6| 7| 7| 6|                                            |            |
                             DAY ON TEST   | 5| 3| 3| 2| 3| 5| 2| 3| 3| 9|                                            |            |
                                           | 6| 5| 0| 5| 5| 6| 2| 0| 4| 7|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|                                            |      A     |
    CONTROL                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|                                            |      L     |
    F                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 RESPIRATORY SYSTEM - cont                 |                                                                          |            |
                                           |                                                                          |            |
      Hyperplasia, Focal, Adenomatous      |                                                                          |      1  2.0|
      Infiltration Cellular, Diffuse,      |                                                                          |            |
          Histiocyte                       |          2                                                               |      1  2.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |    3  2  3  1        1  1  2                                             |     35  1.8|
      Mediastinum, Bacterium               |                                                                          |      1     |
      Mediastinum, Inflammation, Chronic,  |                                                                          |            |
           Multifocal                      |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Nose                                    |    +  +  +  +     +  +  +  +                                             |  50        |
      Foreign Body                         |                                                                          |      2  1.0|
      Inflammation, Acute                  |                                                                          |      3  1.3|
      Nasolacrimal Duct, Inflammation,     |                                                                          |            |
           Chronic                         |                   2                                                      |      1  2.0|
                                            __________________________________________________________________________|____________|
   Trachea                                 |    +  +  +  +     +  +  +  +                                             |  50        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Eye                                     |                                                                          |   2        |
      Degeneration, Chronic, Diffuse       |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  |    +  +  +  +     +  +  +  +                                             |  50        |
      Infiltration Cellular, Focal,        |                                                                          |            |
          Mononuclear Cell                 |                                                                          |      1  2.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |    1  3  3           2     3                                             |     34  1.8|
      Glomerulus, Amyloid Deposition,      |                                                                          |            |
          Diffuse                          |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         |    +  +  +  +     M  +  +  +                                             |  48        |
      Infiltration Cellular, Focal,        |                                                                          |            |
          Mononuclear Cell                 |                                                                          |      1  3.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |                            3                                             |      6  2.2|
      Serosa, Inflammation, Acute          |                                                                          |      1  2.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  16                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 6| 6| 7| 6| 4| 4| 7| 7| 7| 1| 7| 7| 7| 7| 4| 7| 6| 6| 7| 0| 7| 7| 7| 7|             
                             DAY ON TEST   | 5| 8| 0| 3| 6| 5| 5| 3| 3| 3| 2| 3| 3| 3| 3| 5| 3| 2| 9| 3| 0| 3| 3| 3| 3|             
                                           | 6| 2| 4| 0| 6| 6| 6| 5| 4| 0| 4| 4| 0| 3| 4| 6| 5| 6| 9| 5| 5| 3| 4| 4| 5|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    112MG/KG                               | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large                         |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |                                                                          |             
      Serosa, Inflammation, Chronic,       |                                                                          |             
          Diffuse                          |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |                                                                          |             
      Serosa, Inflammation, Chronic,       |                                                                          |             
          Diffuse                          |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small                         |                         +           +                                    |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               |                                     +                                    |             
      Hyperplasia, Atypical, Focal         |                                     3                                    |             
      Serosa, Inflammation, Chronic,       |                                                                          |             
          Diffuse                          |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                |                         +                                                |             
      Diverticulum                         |                         3                                                |             
      Serosa, Inflammation, Chronic,       |                                                                          |             
          Diffuse                          |                                                                          |             
                                            __________________________________________________________________________|             
   Liver                                   |                                                    +                     |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |                                                                          |             
      Serosa, Inflammation, Chronic, Focal |                                                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                                          |             
      Cyst                                 |                                                                          |             
      Fat, Necrosis                        |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 |          +                                +                          +   |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    |          +                                +                          +   |             
      Hyperplasia, Focal, Squamous         |                                                                      2   |             
      Hyperplasia, Multifocal, Squamous    |          3                                                               |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |                                                             +            |             
      Epicardium, Inflammation, Diffuse,   |                                                                          |             
           Subacute                        |                                                             3            |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |                                                                          |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         |          +                 +     +     +              +                 +|             
      Pars Distalis, Congestion, Diffuse   |                                                                          |             
      Pars Distalis, Hyperplasia, Focal    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  17                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 6| 6| 7| 6| 4| 4| 7| 7| 7| 1| 7| 7| 7| 7| 4| 7| 6| 6| 7| 0| 7| 7| 7| 7|             
                             DAY ON TEST   | 5| 8| 0| 3| 6| 5| 5| 3| 3| 3| 2| 3| 3| 3| 3| 5| 3| 2| 9| 3| 0| 3| 3| 3| 3|             
                                           | 6| 2| 4| 0| 6| 6| 6| 5| 4| 0| 4| 4| 0| 3| 4| 6| 5| 6| 9| 5| 5| 3| 4| 4| 5|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    112MG/KG                               | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   |                      +  +        +        +                              |             
      Cyst                                 |                      X  X                 X                              |             
      Cyst Multilocular                    |                                  X        X                              |             
                                            __________________________________________________________________________|             
   Uterus                                  |       +              +  +  +     +  +  +  +     +        +     +  +  +  +|             
      Hemorrhage, Chronic                  |                                                                         3|             
      Hyperplasia, Chronic, Cystic, Diffuse|       4              4  2  3     3  3  2  3     3        3     3  3  2  2|             
      Serosa, Inflammation, Chronic,       |                                                                          |             
          Diffuse                          |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              |    +                                               +                     |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |    +                                               +                     |             
                                            __________________________________________________________________________|             
   Spleen                                  |    +                       +                       +                     |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |                                                                          |             
                                            __________________________________________________________________________|             
   Thymus                                  |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |                                        +                                 |             
                                            __________________________________________________________________________|             
   Skin                                    |                                     +                                    |             
      Inflammation, Chronic                |                                     2                                    |             
      Subcutaneous Tissue, Necrosis        |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                                                          |             
      Hemorrhage, Acute                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |             +                             +                 +            |             
      Abscess                              |                                                             4            |             
      Atelectasis, Diffuse                 |                                                                          |             
      Congestion, Diffuse                  |             2                                                            |             
      Foreign Body                         |                                                                          |             
      Alveolus, Infiltration Cellular,     |                                                                          |             
           Histiocyte                      |                                                                          |             
      Bronchiole, Inflammation, Acute      |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  18                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 6| 6| 7| 6| 4| 4| 7| 7| 7| 1| 7| 7| 7| 7| 4| 7| 6| 6| 7| 0| 7| 7| 7| 7|             
                             DAY ON TEST   | 5| 8| 0| 3| 6| 5| 5| 3| 3| 3| 2| 3| 3| 3| 3| 5| 3| 2| 9| 3| 0| 3| 3| 3| 3|             
                                           | 6| 2| 4| 0| 6| 6| 6| 5| 4| 0| 4| 4| 0| 3| 4| 6| 5| 6| 9| 5| 5| 3| 4| 4| 5|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    112MG/KG                               | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  |                                                    +                     |             
      Nephropathy, Diffuse                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  19                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 6| 7| 7| 7| 7| 2| 4| 4| 7| 7| 7| 7| 5| 7| 6| 0| 4| 4| 4| 7| 4| 7| 7| 7| 7|             
                             DAY ON TEST   | 0| 3| 3| 3| 3| 6| 5| 5| 3| 3| 1| 3| 8| 3| 0| 0| 5| 5| 8| 3| 5| 3| 3| 3| 3|             
                                           | 0| 0| 5| 3| 3| 0| 6| 6| 4| 4| 5| 3| 2| 0| 4| 7| 6| 6| 4| 3| 6| 5| 5| 0| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    112MG/KG                               | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|             
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large                         |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |                                                                          |             
      Serosa, Inflammation, Chronic,       |                                                                          |             
          Diffuse                          |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |                                                                          |             
      Serosa, Inflammation, Chronic,       |                                                                          |             
          Diffuse                          |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small                         |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               |                                                                          |             
      Hyperplasia, Atypical, Focal         |                                                                          |             
      Serosa, Inflammation, Chronic,       |                                                                          |             
          Diffuse                          |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                |                                                                          |             
      Diverticulum                         |                                                                          |             
      Serosa, Inflammation, Chronic,       |                                                                          |             
          Diffuse                          |                                                                          |             
                                            __________________________________________________________________________|             
   Liver                                   |       +                                                  +               |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |                                                                          |             
      Serosa, Inflammation, Chronic, Focal |                                                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                       +                  |             
      Cyst                                 |                                                       X                  |             
      Fat, Necrosis                        |                                                       4                  |             
                                            __________________________________________________________________________|             
   Stomach                                 |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    |                                                                          |             
      Hyperplasia, Focal, Squamous         |                                                                          |             
      Hyperplasia, Multifocal, Squamous    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |                                                                          |             
      Epicardium, Inflammation, Diffuse,   |                                                                          |             
           Subacute                        |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |                                                                          |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         |                               +                                          |             
      Pars Distalis, Congestion, Diffuse   |                               3                                          |             
      Pars Distalis, Hyperplasia, Focal    |                               2                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  20                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 6| 7| 7| 7| 7| 2| 4| 4| 7| 7| 7| 7| 5| 7| 6| 0| 4| 4| 4| 7| 4| 7| 7| 7| 7|             
                             DAY ON TEST   | 0| 3| 3| 3| 3| 6| 5| 5| 3| 3| 1| 3| 8| 3| 0| 0| 5| 5| 8| 3| 5| 3| 3| 3| 3|             
                                           | 0| 0| 5| 3| 3| 0| 6| 6| 4| 4| 5| 3| 2| 0| 4| 7| 6| 6| 4| 3| 6| 5| 5| 0| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    112MG/KG                               | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|             
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   |    +     +              +     +  +                                       |             
      Cyst                                 |    X     X                    X  X                                       |             
      Cyst Multilocular                    |                         X                                                |             
                                            __________________________________________________________________________|             
   Uterus                                  |    +  +  +  +           +  +  +  +        +              +     +  +  +  +|             
      Hemorrhage, Chronic                  |                                                                          |             
      Hyperplasia, Chronic, Cystic, Diffuse|    3  2  4  2           4  2  3  4        2              4     4  4  2  2|             
      Serosa, Inflammation, Chronic,       |                                                                          |             
          Diffuse                          |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +                                   +                                    |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |                                     +                                    |             
                                            __________________________________________________________________________|             
   Spleen                                  | +                             +     +     +                       +  +   |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |                                           3                              |             
                                            __________________________________________________________________________|             
   Thymus                                  |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    |                                     +                 +                  |             
      Inflammation, Chronic                |                                                                          |             
      Subcutaneous Tissue, Necrosis        |                                                       4                  |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         | +                                                                        |             
      Hemorrhage, Acute                    | 4                                                                        |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |                                        +     +           +               |             
      Abscess                              |                                                                          |             
      Atelectasis, Diffuse                 |                                              4                           |             
      Congestion, Diffuse                  |                                                                          |             
      Foreign Body                         |                                              3                           |             
      Alveolus, Infiltration Cellular,     |                                                                          |             
           Histiocyte                      |                                                          3               |             
      Bronchiole, Inflammation, Acute      |                                              4                           |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  21                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 6| 7| 7| 7| 7| 2| 4| 4| 7| 7| 7| 7| 5| 7| 6| 0| 4| 4| 4| 7| 4| 7| 7| 7| 7|             
                             DAY ON TEST   | 0| 3| 3| 3| 3| 6| 5| 5| 3| 3| 1| 3| 8| 3| 0| 0| 5| 5| 8| 3| 5| 3| 3| 3| 3|             
                                           | 0| 0| 5| 3| 3| 0| 6| 6| 4| 4| 5| 3| 2| 0| 4| 7| 6| 6| 4| 3| 6| 5| 5| 0| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    112MG/KG                               | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|             
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  |                                                       +                  |             
      Nephropathy, Diffuse                 |                                                       4                  |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  22                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 6| 7| 7| 6| 4| 7| 7| 6| 7|                                            |            |
                             DAY ON TEST   | 3| 9| 3| 3| 0| 5| 3| 3| 3| 3|                                            |            |
                                           | 3| 9| 5| 3| 1| 6| 4| 0| 9| 0|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|                                            |      A     |
    112MG/KG                               | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|                                            |      L     |
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +                                                                        |   1        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +                                                                        |   1        |
      Serosa, Inflammation, Chronic,       |                                                                          |            |
          Diffuse                          | 4                                                                        |      1  4.0|
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | +                                                                        |   1        |
      Serosa, Inflammation, Chronic,       |                                                                          |            |
          Diffuse                          | 2                                                                        |      1  2.0|
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +                                                                        |   1        |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +                                                                        |   3        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +                                                                        |   2        |
      Hyperplasia, Atypical, Focal         |                                                                          |      1  3.0|
      Serosa, Inflammation, Chronic,       |                                                                          |            |
          Diffuse                          | 3                                                                        |      1  3.0|
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +                                                                        |   1        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +                                                                        |   2        |
      Diverticulum                         |                                                                          |      1  3.0|
      Serosa, Inflammation, Chronic,       |                                                                          |            |
          Diffuse                          | 4                                                                        |      1  4.0|
                                            __________________________________________________________________________|____________|
   Liver                                   | +        +                                                               |   5        |
      Hematopoietic Cell Proliferation,    |                                                                          |            |
           Diffuse                         |          4                                                               |      1  4.0|
      Serosa, Inflammation, Chronic, Focal | 2                                                                        |      1  2.0|
                                            __________________________________________________________________________|____________|
   Mesentery                               |                                                                          |   1        |
      Cyst                                 |                                                                          |      1     |
      Fat, Necrosis                        |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Stomach                                 |                                                                          |   3        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    |                                                                          |   3        |
      Hyperplasia, Focal, Squamous         |                                                                          |      1  2.0|
      Hyperplasia, Multifocal, Squamous    |                                                                          |      1  3.0|
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Heart                                   |                                                                          |   1        |
      Epicardium, Inflammation, Diffuse,   |                                                                          |            |
           Subacute                        |                                                                          |      1  3.0|
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         |                                                                          |   7        |
      Pars Distalis, Congestion, Diffuse   |                                                                          |      1  3.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  23                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 6| 7| 7| 6| 4| 7| 7| 6| 7|                                            |            |
                             DAY ON TEST   | 3| 9| 3| 3| 0| 5| 3| 3| 3| 3|                                            |            |
                                           | 3| 9| 5| 3| 1| 6| 4| 0| 9| 0|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|                                            |      A     |
    112MG/KG                               | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|                                            |      L     |
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
      Pars Distalis, Hyperplasia, Focal    |                                                                          |      1  2.0|
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Ovary                                   |                      +     +                                             |  11        |
      Cyst                                 |                      X                                                   |      8     |
      Cyst Multilocular                    |                            X                                             |      4     |
                                            __________________________________________________________________________|____________|
   Uterus                                  | +     +  +  +     +  +  +  +                                             |  36        |
      Hemorrhage, Chronic                  |                                                                          |      1  3.0|
      Hyperplasia, Chronic, Cystic, Diffuse| 3     2  3  4     4  4     4                                             |     35  3.0|
      Serosa, Inflammation, Chronic,       |                                                                          |            |
          Diffuse                          | 3                                                                        |      1  3.0|
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lymph Node                              |    +        +           +                                                |   7        |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  |    +        +           +                                                |   6        |
                                            __________________________________________________________________________|____________|
   Spleen                                  |    +     +  +                                                            |  12        |
      Hematopoietic Cell Proliferation,    |                                                                          |            |
           Diffuse                         |          4                                                               |      2  3.5|
                                            __________________________________________________________________________|____________|
   Thymus                                  |    +                                                                     |   1        |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Skin                                    |                   +  +  +                                                |   6        |
      Inflammation, Chronic                |                   2  1                                                   |      3  1.7|
      Subcutaneous Tissue, Necrosis        |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Skeletal Muscle                         |                                                                          |   1        |
      Hemorrhage, Acute                    |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    |    +                                                                     |   7        |
      Abscess                              |                                                                          |      1  4.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  24                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 6| 7| 7| 6| 4| 7| 7| 6| 7|                                            |            |
                             DAY ON TEST   | 3| 9| 3| 3| 0| 5| 3| 3| 3| 3|                                            |            |
                                           | 3| 9| 5| 3| 1| 6| 4| 0| 9| 0|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|                                            |      A     |
    112MG/KG                               | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|                                            |      L     |
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 RESPIRATORY SYSTEM - cont                 |                                                                          |            |
                                           |                                                                          |            |
      Atelectasis, Diffuse                 |                                                                          |      1  4.0|
      Congestion, Diffuse                  |    3                                                                     |      2  2.5|
      Foreign Body                         |                                                                          |      1  3.0|
      Alveolus, Infiltration Cellular,     |                                                                          |            |
           Histiocyte                      |                                                                          |      1  3.0|
      Bronchiole, Inflammation, Acute      |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  |                         +                                                |   3        |
      Nephropathy, Diffuse                 |                                                                          |      1  4.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  25                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 7| 6| 7| 7| 1| 3| 4| 7| 6| 4| 4| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 7| 6|             
                             DAY ON TEST   | 4| 3| 3| 3| 3| 4| 1| 5| 3| 3| 0| 5| 3| 3| 3| 5| 3| 3| 3| 3| 3| 3| 3| 3| 8|             
                                           | 3| 4| 2| 0| 4| 0| 3| 6| 3| 6| 0| 6| 4| 3| 5| 6| 3| 3| 5| 4| 5| 0| 4| 5| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    225MG/KG                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  M|             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                                          |             
                                            __________________________________________________________________________|             
   Gallbladder                             | A  +  +  +  +  A  +     +  +  A     +  +  +     +  +  +  +  +  +  +  +  M|             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
      Anorectal Junction, Inflammation,    |                                                                          |             
           Chronic, Focal                  |                                                 4                        |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | A  +  +  +  +  A  +     +  +  A     +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  A  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | A  +  +  +  +  A  +     +  +  A     +  +  +     +  +  +  +  +  +  +  +  A|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | A  +  +  +  +  A  +     +  +  A     +  +  +     +  +  +  +  +  +  +  +  A|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | A  +  +  +  +  A  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  A|             
      Diverticulum                         |                                                                   4      |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
      Erythrophagocytosis, Diffuse         |                                                                          |             
      Fatty Change, Diffuse                |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                     1     1                       1      |             
      Inflammation, Focal, Subacute        |                   1                                                      |             
      Necrosis, Acute, Focal               |                                                                          |             
      Pigmentation, Diffuse, Hemosiderin   |                                                                          |             
      Centrilobular, Fatty Change          |                               2                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                                +         |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +     +  +  M     +  +  +     +  +  +  +  +  +  +  +  M|             
      Hyperplasia, Glandular, Multifocal   |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +  +     +  +  +     +  +  M     +  +  +  +  +  +  +  +  M|             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |    2  1  2                          3  1        2  2                     |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  M|             
      Hyperplasia, Focal, Squamous         |                                     2              2              2      |             
      Hyperplasia, Multifocal, Squamous    |                         2                                                |             
      Inflammation, Subacute               |                                                                          |             
      Ulcer, Acute, Multifocal             |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  M|             
      Erosion, Focal                       |                            3                                             |             
      Ulcer, Acute, Focal                  |                                                                          |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  26                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 7| 6| 7| 7| 1| 3| 4| 7| 6| 4| 4| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 7| 6|             
                             DAY ON TEST   | 4| 3| 3| 3| 3| 4| 1| 5| 3| 3| 0| 5| 3| 3| 3| 5| 3| 3| 3| 3| 3| 3| 3| 3| 8|             
                                           | 3| 4| 2| 0| 4| 0| 3| 6| 3| 6| 0| 6| 4| 3| 5| 6| 3| 3| 5| 4| 5| 0| 4| 5| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    225MG/KG                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM - cont              |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  M|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
      Hypertrophy, Focal                   |    2                                                                     |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +  +     +  +  M     +  +  +     +  +  M  +  +  +  +  +  M|             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | M  +  +  M  M  M  +     M  M  +     M  M  +     M  +  M  M  M  +  +  M  M|             
      Cyst                                 |                                                                          |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
      Pars Distalis, Hyperplasia, Focal    |                         2              3  3     3  3        3            |             
      Pars Distalis, Hyperplasia,          |                                                                          |             
          Multifocal                       |                                                                      3   |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  M|             
      Depletion Secretory                  |             X                                                            |             
      Follicular Cell, Hyperplasia         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   | +  +  +  I  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
      Angiectasis, Focal                   |                                                                          |             
      Cyst                                 |       X                                                           X      |             
      Cyst Multilocular                    |                                           X                    X     X   |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                        3           2                     |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
      Amyloid Deposition, Diffuse          |                                                                          |             
      Dilatation                           |                                                                          |             
      Hemorrhage, Chronic                  |                                                                          |             
      Hyperplasia, Chronic, Cystic, Diffuse|    3  3  3        3     4  4        3  3  4     4  4  4  4  3  4  4  3  2|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
      Pigmentation, Diffuse, Hemosiderin   |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +  +  M  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |                                                                          |             
      Hyperplasia, Lymphoid                |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  M|             
      Congestion, Diffuse                  |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  27                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 7| 6| 7| 7| 1| 3| 4| 7| 6| 4| 4| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 7| 6|             
                             DAY ON TEST   | 4| 3| 3| 3| 3| 4| 1| 5| 3| 3| 0| 5| 3| 3| 3| 5| 3| 3| 3| 3| 3| 3| 3| 3| 8|             
                                           | 3| 4| 2| 0| 4| 0| 3| 6| 3| 6| 0| 6| 4| 3| 5| 6| 3| 3| 5| 4| 5| 0| 4| 5| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    225MG/KG                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Erythrophagocytosis, Diffuse         |                                                                          |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |    2                                                                     |             
      Hyperplasia, Lymphoid                |                                                    2     4               |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +  +  +  M  +  +     +  M  M     +  +  +     M  +  M  M  +  +  M  +  M|             
      Atrophy, Diffuse                     |                                                                          |             
      Medulla, Hyperplasia, Focal, Lymphoid|                                                                2         |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
      Inflammation, Chronic                |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
      Inflammation, Chronic                |                                                 2  2  2  2  1        3   |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
      Osteoporosis                         |                                     4                                    |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
      Mineralization, Multifocal           |    1     2                             1  1        1  1     1     1  1   |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  M|             
      Congestion, Diffuse                  | 4                                                                        |             
      Hyperplasia, Focal, Adenomatous      |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |    2  1  2     1        1  1        1  1  2     2  2  2  2     2  1  1   |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
      Foreign Body                         |             1                                                            |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  M|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ear                                     |                                                       +                  |             
                                            __________________________________________________________________________|             
   Eye                                     |                                                                          |             
      Degeneration, Chronic, Diffuse       |                                                                          |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
      Casts                                |                                                                          |             
      Cyst                                 |                                           X                              |             
      Hydronephrosis                       |                                                                      4   |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  28                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 7| 6| 7| 7| 1| 3| 4| 7| 6| 4| 4| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 7| 6|             
                             DAY ON TEST   | 4| 3| 3| 3| 3| 4| 1| 5| 3| 3| 0| 5| 3| 3| 3| 5| 3| 3| 3| 3| 3| 3| 3| 3| 8|             
                                           | 3| 4| 2| 0| 4| 0| 3| 6| 3| 6| 0| 6| 4| 3| 5| 6| 3| 3| 5| 4| 5| 0| 4| 5| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    225MG/KG                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
          Cell, Multifocal                 |    1  3  2        1     1  1  1     1  1        1  3  1  1  1        4  1|             
      Nephropathy, Diffuse                 |                                                                          |             
      Glomerulus, Amyloid Deposition,      |                                                                          |             
          Diffuse                          |                                                                          |             
      Papilla, Mineralization, Multifocal  |                                                                          |             
                                            __________________________________________________________________________|             
   Ureter                                  |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | A  +  +  +  +  A  +     +  +  +     +  +  +     +  +  +  +  +  +  +  +  +|             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell                             |                                                    2                     |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                        3                                 |             
      Inflammation, Diffuse, Subacute      |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  29                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 1| 4| 6| 6| 6| 4| 4| 7| 7| 7| 4| 4| 7| 7| 7| 7| 7| 7| 7| 7| 4| 7| 7| 6| 7|             
                             DAY ON TEST   | 5| 5| 8| 7| 8| 5| 5| 3| 3| 3| 5| 9| 3| 3| 0| 3| 3| 3| 3| 3| 5| 3| 3| 2| 3|             
                                           | 5| 6| 2| 6| 1| 6| 6| 0| 3| 5| 6| 7| 0| 3| 8| 3| 4| 4| 5| 3| 6| 0| 0| 1| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
    225MG/KG                               | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                            1                                             |             
                                            __________________________________________________________________________|             
   Gallbladder                             | A     +  A  +        +  +  +     +  +  +  A  M  +  +  +  +     +  +  A  +|             
                                            __________________________________________________________________________|             
   Intestine Large                         | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Anorectal Junction, Inflammation,    |                                                                          |             
           Chronic, Focal                  |                                              4                           |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | A     +  +  +        +  +  +     A  +  +  A  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | A     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small                         | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | A     +  +  +        +  +  +     A  +  +  +  +  +  +  +  +     +  +  A  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | A     +  +  +        +  +  +     A  +  +  A  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | A     +  +  +        +  +  +     A  +  +  A  +  +  +  +  +     +  +  +  +|             
      Diverticulum                         |                                                                          |             
                                            __________________________________________________________________________|             
   Liver                                   | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Erythrophagocytosis, Diffuse         |       2     2                                                            |             
      Fatty Change, Diffuse                |             3                                                            |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                            1              2     1  2              1      |             
      Inflammation, Focal, Subacute        |                                                                          |             
      Necrosis, Acute, Focal               |       1                                                                  |             
      Pigmentation, Diffuse, Hemosiderin   |       2     2                                                            |             
      Centrilobular, Fatty Change          |                                                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                    +                     |             
                                            __________________________________________________________________________|             
   Pancreas                                | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Hyperplasia, Glandular, Multifocal   |          2                                                               |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +     +  +  +        +  +  +     M  +  +  +  +  +  +  +  +     +  +  +  +|             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |          1                                                               |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                      1     1        1     1  1        1  2     1  2      |             
                                            __________________________________________________________________________|             
   Stomach                                 | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | A     +  +  +           +  +     I  +  +  +  +  +  +  +  +     +  +  +  +|             
      Hyperplasia, Focal, Squamous         |                         3                                      1         |             
      Hyperplasia, Multifocal, Squamous    |                                                                          |             
      Inflammation, Subacute               |             2                                                            |             
      Ulcer, Acute, Multifocal             |             2                                                            |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | A     +  +  +           +  +     I  +  +  +  +  +  +  +  +     +  +  +  +|             
      Erosion, Focal                       |                                           1                              |             
      Ulcer, Acute, Focal                  |             3                                                            |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                                                      +   |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  30                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 1| 4| 6| 6| 6| 4| 4| 7| 7| 7| 4| 4| 7| 7| 7| 7| 7| 7| 7| 7| 4| 7| 7| 6| 7|             
                             DAY ON TEST   | 5| 5| 8| 7| 8| 5| 5| 3| 3| 3| 5| 9| 3| 3| 0| 3| 3| 3| 3| 3| 5| 3| 3| 2| 3|             
                                           | 5| 6| 2| 6| 1| 6| 6| 0| 3| 5| 6| 7| 0| 3| 8| 3| 4| 4| 5| 3| 6| 0| 0| 1| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
    225MG/KG                               | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM - cont              |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +     +  +  +        +  +  +     +  +     +  +  +  +  +  +     +  +  +  +|             
      Hypertrophy, Focal                   |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | M     +  +  +        +  +  +     +  +     +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | A     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | M     M  M  +        M  M  +     +  +  M  M  +  M  +  +  M     M  M  M  +|             
      Cyst                                 |                                                                          |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Pars Distalis, Hyperplasia, Focal    |                      2                                1        3         |             
      Pars Distalis, Hyperplasia,          |                                                                          |             
          Multifocal                       |                                                 3                        |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Depletion Secretory                  |                                                                          |             
      Follicular Cell, Hyperplasia         |                                                                2         |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Angiectasis, Focal                   |                                                                          |             
      Cyst                                 |                                                 X  X                     |             
      Cyst Multilocular                    |             X                                                            |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                            2                                             |             
                                            __________________________________________________________________________|             
   Uterus                                  | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Amyloid Deposition, Diffuse          |                                           3                              |             
      Dilatation                           |                                                       4                  |             
      Hemorrhage, Chronic                  |          4                                                               |             
      Hyperplasia, Chronic, Cystic, Diffuse|          2  2        3  3  4        4  4  3  3  4  2     3     4  3  3  4|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Pigmentation, Diffuse, Hemosiderin   |       3                                                                  |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +     +  +  I        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |                                                                      3   |             
      Hyperplasia, Lymphoid                |                         4                                                |             
                                            __________________________________________________________________________|             
   Spleen                                  | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Congestion, Diffuse                  |       4     4                                                            |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  31                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 1| 4| 6| 6| 6| 4| 4| 7| 7| 7| 4| 4| 7| 7| 7| 7| 7| 7| 7| 7| 4| 7| 7| 6| 7|             
                             DAY ON TEST   | 5| 5| 8| 7| 8| 5| 5| 3| 3| 3| 5| 9| 3| 3| 0| 3| 3| 3| 3| 3| 5| 3| 3| 2| 3|             
                                           | 5| 6| 2| 6| 1| 6| 6| 0| 3| 5| 6| 7| 0| 3| 8| 3| 4| 4| 5| 3| 6| 0| 0| 1| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
    225MG/KG                               | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Erythrophagocytosis, Diffuse         |       4     3                                                            |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |          3                 4     3                                      3|             
      Hyperplasia, Lymphoid                |                            3                                             |             
                                            __________________________________________________________________________|             
   Thymus                                  | +     I  +  M        +  +  +     +  +  +  M  +  +  +  +  +     +  +  +  +|             
      Atrophy, Diffuse                     |          4                                                           4   |             
      Medulla, Hyperplasia, Focal, Lymphoid|                                     2                                   3|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +     +  M  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Inflammation, Chronic                |                                                                      4   |             
                                            __________________________________________________________________________|             
   Skin                                    | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Inflammation, Chronic                |                                              1                           |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Osteoporosis                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Mineralization, Multifocal           |                      2  1                 1     1  1     1        1     2|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Congestion, Diffuse                  | 4                                                                        |             
      Hyperplasia, Focal, Adenomatous      |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                      2  1  3     2  2  2  2  2  1     2  1     2  1     2|             
                                            __________________________________________________________________________|             
   Nose                                    | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Foreign Body                         |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ear                                     |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |          +                                                               |             
      Degeneration, Chronic, Diffuse       |          4                                                               |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |          +           +                                                  +|             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +     +  +  +        +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Casts                                |       X     X                                                            |             
      Cyst                                 |          X                                                               |             
      Hydronephrosis                       |          4                                                               |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  32                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 1| 4| 6| 6| 6| 4| 4| 7| 7| 7| 4| 4| 7| 7| 7| 7| 7| 7| 7| 7| 4| 7| 7| 6| 7|             
                             DAY ON TEST   | 5| 5| 8| 7| 8| 5| 5| 3| 3| 3| 5| 9| 3| 3| 0| 3| 3| 3| 3| 3| 5| 3| 3| 2| 3|             
                                           | 5| 6| 2| 6| 1| 6| 6| 0| 3| 5| 6| 7| 0| 3| 8| 3| 4| 4| 5| 3| 6| 0| 0| 1| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
    225MG/KG                               | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
          Cell, Multifocal                 |          2           2  1  2     2  2     1  2  1              1  2     1|             
      Nephropathy, Diffuse                 |       4     3                                                            |             
      Glomerulus, Amyloid Deposition,      |                                                                          |             
          Diffuse                          |                                                                2         |             
      Papilla, Mineralization, Multifocal  |                                                                          |             
                                            __________________________________________________________________________|             
   Ureter                                  |          +                                                               |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | A     +  M  +        +  +  +     I  +  +  +  +  +  +  +  +     +  +  +  +|             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell                             |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                      2     3              2        2                     |             
      Inflammation, Diffuse, Subacute      |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  33                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 4| 7| 6| 7| 6| 4| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 3| 8| 3| 8| 5| 3| 3| 3| 3|                                            |            |
                                           | 6| 4| 8| 5| 5| 6| 0| 0| 3| 5|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|                                            |      A     |
    225MG/KG                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               |    +  +  +  +     +  +  +  +                                             |  49        |
      Infiltration Cellular, Focal,        |                                                                          |            |
          Mononuclear Cell                 |                                                                          |      1  1.0|
                                            __________________________________________________________________________|____________|
   Gallbladder                             |    +  A  +  A     +  +  +  +                                             |  39        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         |    +  +  +  +     +  +  +  +                                             |  50        |
      Anorectal Junction, Inflammation,    |                                                                          |            |
           Chronic, Focal                  |                                                                          |      2  4.0|
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  |    +  +  +  +     +  +  +  +                                             |  44        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  |    +  +  +  +     +  +  +  +                                             |  48        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 |    +  +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small                         |    +  +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               |    +  +  +  A     +  +  +  +                                             |  42        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  |    +  A  +  A     +  +  +  +                                             |  41        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                |    +  A  +  A     +  +  +  +                                             |  42        |
      Diverticulum                         |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Liver                                   |    +  +  +  +     +  +  +  +                                             |  50        |
      Erythrophagocytosis, Diffuse         |       2                                                                  |      3  2.0|
      Fatty Change, Diffuse                |       2                                                                  |      2  2.5|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |                   1                                                      |      9  1.2|
      Inflammation, Focal, Subacute        |                                                                          |      1  1.0|
      Necrosis, Acute, Focal               |                                                                          |      1  1.0|
      Pigmentation, Diffuse, Hemosiderin   |                                                                          |      2  2.0|
      Centrilobular, Fatty Change          |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Mesentery                               |                                                                          |   2        |
                                            __________________________________________________________________________|____________|
   Pancreas                                |    +  +  +  +     +  +  +  +                                             |  48        |
      Hyperplasia, Glandular, Multifocal   |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Salivary Glands                         |    +  +  +  +     +  +  +  +                                             |  47        |
      Infiltration Cellular, Focal,        |                                                                          |            |
          Mononuclear Cell                 |                                                                          |      1  1.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |    1     3  1     1  2     1                                             |     22  1.5|
                                            __________________________________________________________________________|____________|
   Stomach                                 |    +  +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    |    +  +  +  +     +  +  +  +                                             |  46        |
      Hyperplasia, Focal, Squamous         |                                                                          |      5  2.0|
      Hyperplasia, Multifocal, Squamous    |                                                                          |      1  2.0|
      Inflammation, Subacute               |                                                                          |      1  2.0|
      Ulcer, Acute, Multifocal             |       2                                                                  |      2  2.0|
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      |    +  +  +  +     +  +  +  +                                             |  46        |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  34                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 4| 7| 6| 7| 6| 4| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 3| 8| 3| 8| 5| 3| 3| 3| 3|                                            |            |
                                           | 6| 4| 8| 5| 5| 6| 0| 0| 3| 5|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|                                            |      A     |
    225MG/KG                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
      Erosion, Focal                       |                                                                          |      2  2.0|
      Ulcer, Acute, Focal                  |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Tooth                                   |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Heart                                   |    +  +  +  +     +  +  +  +                                             |  49        |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           |    +  +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   |    +  +  +  +     +  +  +  +                                             |  49        |
      Hypertrophy, Focal                   |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  |    +  +  +  +     +  +  +  +                                             |  48        |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      |    +  +  +  +     +  +  +  +                                             |  46        |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       |    +  M  +  M     +  M  M  +                                             |  20        |
      Cyst                                 |    X                                                                     |      1     |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         |    +  +  +  +     +  +  +  +                                             |  50        |
      Pars Distalis, Hyperplasia, Focal    |    1                                                                     |     10  2.4|
      Pars Distalis, Hyperplasia,          |                                                                          |            |
          Multifocal                       |                                                                          |      2  3.0|
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           |    +  +  +  +     +  +  +  +                                             |  49        |
      Depletion Secretory                  |                                                                          |      1     |
      Follicular Cell, Hyperplasia         |                                                                          |      1  2.0|
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Ovary                                   |    +  +  +  +     +  +  +  +                                             |  49        |
      Angiectasis, Focal                   |             3                                                            |      1  3.0|
      Cyst                                 |             X           X  X                                             |      7     |
      Cyst Multilocular                    |                                                                          |      4     |
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |                                                                          |      3  2.3|
                                            __________________________________________________________________________|____________|
   Uterus                                  |    +  +  +  +     +  +  +  +                                             |  50        |
      Amyloid Deposition, Diffuse          |                                                                          |      1  3.0|
      Dilatation                           |                                                                          |      1  4.0|
      Hemorrhage, Chronic                  |                                                                          |      1  4.0|
      Hyperplasia, Chronic, Cystic, Diffuse|    4     3  2     4  3  4  4                                             |     41  3.3|
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  35                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 4| 7| 6| 7| 6| 4| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 3| 8| 3| 8| 5| 3| 3| 3| 3|                                            |            |
                                           | 6| 4| 8| 5| 5| 6| 0| 0| 3| 5|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|                                            |      A     |
    225MG/KG                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             |    +  +  +  +     +  +  +  +                                             |  50        |
      Pigmentation, Diffuse, Hemosiderin   |       2                                                                  |      2  2.5|
                                            __________________________________________________________________________|____________|
   Lymph Node                              |    +  +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  |    +  +  +  +     +  +  +  +                                             |  48        |
      Hematopoietic Cell Proliferation,    |                                                                          |            |
           Diffuse                         |                                                                          |      1  3.0|
      Hyperplasia, Lymphoid                |             3                                                            |      2  3.5|
                                            __________________________________________________________________________|____________|
   Spleen                                  |    +  +  +  +     +  +  +  +                                             |  49        |
      Congestion, Diffuse                  |                                                                          |      2  4.0|
      Erythrophagocytosis, Diffuse         |       4                                                                  |      3  3.7|
      Hematopoietic Cell Proliferation,    |                                                                          |            |
           Diffuse                         |    2                       3                                             |      7  2.9|
      Hyperplasia, Lymphoid                |                                                                          |      3  3.0|
                                            __________________________________________________________________________|____________|
   Thymus                                  |    +  +  +  +     +  +  +  +                                             |  39        |
      Atrophy, Diffuse                     |       3                                                                  |      3  3.7|
      Medulla, Hyperplasia, Focal, Lymphoid|                      3                                                   |      4  2.5|
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           |    +  +  +  +     M  +  +  +                                             |  48        |
      Inflammation, Chronic                |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Skin                                    |    +  +  +  +     +  +  +  +                                             |  50        |
      Inflammation, Chronic                |                                                                          |      7  1.9|
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    |    +  +  +  +     +  +  +  +                                             |  50        |
      Osteoporosis                         |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   |    +  +  +  +     +  +  +  +                                             |  50        |
      Mineralization, Multifocal           |                      2  1                                                |     19  1.2|
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    |    +  +  +  +     +  +  +  +                                             |  49        |
      Congestion, Diffuse                  |             3                                                            |      3  3.7|
      Hyperplasia, Focal, Adenomatous      |             2                                                            |      1  2.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |    2     1           3  2  1                                             |     35  1.7|
                                            __________________________________________________________________________|____________|
   Nose                                    |    +  +  +  +     +  +  +  +                                             |  50        |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  36                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 4| 7| 6| 7| 6| 4| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 3| 8| 3| 8| 5| 3| 3| 3| 3|                                            |            |
                                           | 6| 4| 8| 5| 5| 6| 0| 0| 3| 5|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|                                            |      A     |
    225MG/KG                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
     FEMALE                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 RESPIRATORY SYSTEM - cont                 |                                                                          |            |
                                           |                                                                          |            |
      Foreign Body                         |                                                                          |      1  1.0|
                                            __________________________________________________________________________|____________|
   Trachea                                 |    +  +  +  +     +  +  +  +                                             |  49        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Ear                                     |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Eye                                     |                                                                          |   1        |
      Degeneration, Chronic, Diffuse       |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Harderian Gland                         |                                                                          |   3        |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  |    +  +  +  +     +  +  +  +                                             |  50        |
      Casts                                |       X                                                                  |      3     |
      Cyst                                 |                                                                          |      2     |
      Hydronephrosis                       |    4                                                                     |      3  4.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |          2  1        2     1                                             |     32  1.5|
      Nephropathy, Diffuse                 |       4                                                                  |      3  3.7|
      Glomerulus, Amyloid Deposition,      |                                                                          |            |
          Diffuse                          |                                                                          |      1  2.0|
      Papilla, Mineralization, Multifocal  |       2                                                                  |      1  2.0|
                                            __________________________________________________________________________|____________|
   Ureter                                  |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         |    +  +  +  +     +  +  +  +                                             |  45        |
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell                             |                                                                          |      1  2.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |                                                                          |      5  2.4|
      Inflammation, Diffuse, Subacute      |             2                                                            |      1  2.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  37                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 4| 7| 7| 4| 6| 7| 7| 7| 6| 7| 7| 7| 7| 5| 7| 7| 6| 7| 4| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 5| 3| 3| 5| 9| 3| 3| 3| 2| 3| 3| 3| 3| 6| 1| 3| 3| 3| 5| 3| 3| 3| 3|             
                                           | 3| 3| 6| 4| 5| 6| 2| 3| 5| 3| 8| 4| 4| 5| 3| 7| 1| 4| 5| 3| 6| 5| 3| 0| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    M                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Gallbladder                             | +  +     +  +     +  +  +  +  +  +  +  +  +  I  +  +  A  M     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Parasite Metazoan                    |                                                                      X   |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +     +  +     M  +  +  +  +  +  +  +  +  +  +  +  +  +     I  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Diverticulum                         |                                                 4                        |             
      Hyperplasia, Focal, Lymphoid         |                                     4                                    |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Basophilic Focus                     |                                                    X                     |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Multifocal                      |                   2                                                      |             
      Inclusion Body Intranuclear, Diffuse |                                                                          |             
      Infarct                              |                                                                          |             
      Karyomegaly, Diffuse                 |                                                                          |             
      Necrosis, Acute, Focal               |                                                 2  2                     |             
      Centrilobular, Fatty Change          |                                                                2         |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Atrophy, Focal                       |                                                                      1   |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |    1              1           1     2     2                       2  1  1|             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Cyst                                 |                                                                          |             
      Diverticulum, Focal                  |                                                                          |             
      Hyperplasia, Focal, Squamous         |                                                                   2      |             
      Inflammation, Chronic, Focal         |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +     +  +     +  +  +  +  +  +  +  +  +  +     +  +  +     +  +  +  +|             
      Cyst, Focal                          |             1                                                            |             
      Cyst Epithelial Inclusion, Focal     |                                  1                                       |             
      Degeneration, Cystic, Focal          |                                                                          |             
      Erosion, Focal                       |                                                                          |             
                                            __________________________________________________________________________|             
   Tooth                                   |                      +                    +        +           +     +   |             
      Inflammation, Chronic                |                      4                    2        2           4     3   |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  38                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 4| 7| 7| 4| 6| 7| 7| 7| 6| 7| 7| 7| 7| 5| 7| 7| 6| 7| 4| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 5| 3| 3| 5| 9| 3| 3| 3| 2| 3| 3| 3| 3| 6| 1| 3| 3| 3| 5| 3| 3| 3| 3|             
                                           | 3| 3| 6| 4| 5| 6| 2| 3| 5| 3| 8| 4| 4| 5| 3| 7| 1| 4| 5| 3| 6| 5| 3| 0| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    M                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM - cont              |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Atrium, Thrombosis                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Hyperplasia, Focal                   |                                  2                                       |             
      Hypertrophy, Focal                   |             1                                                        1   |             
      Hypertrophy, Multifocal              |                                                                          |             
      Spindle Cell, Hyperplasia, Focal     |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +     +  +     +  +  +  +  +  +  +  +  M  +  +  +  +  +     +  +  +  M|             
      Hyperplasia, Multifocal              |                                                                          |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Hyperplasia, Focal                   |                         3        2                                      3|             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +     +  I     +  M  M  +  M  M  I  +  +  I  +  M  M  M     +  I  M  I|             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +     +  +     +  +  +  +  +  +  +  +  +  M  +  +  M  +     +  +  +  +|             
      Pars Distalis, Cyst                  |                                     X                                    |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +     +  +     +  +  +  +  M  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Cyst                                 |                                        X                                 |             
      Follicular Cell, Hyperplasia         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                  1                                       |             
                                            __________________________________________________________________________|             
   Penis                                   |                         +                                                |             
      Congestion                           |                         3                                                |             
      Inflammation, Chronic                |                         2                                                |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |                            +                          +                  |             
      Abscess                              |                            4                                             |             
      Inflammation, Chronic                |                                                       3                  |             
                                            __________________________________________________________________________|             
   Prostate                                | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Testes                                  | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Atrophy, Diffuse                     |                                                                          |             
      Granuloma Sperm, Focal               |                                                                          |             
      Mineralization, Focal                |                                     1  1                                 |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Hyperplasia, Lymphoid                |                               2                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  39                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 4| 7| 7| 4| 6| 7| 7| 7| 6| 7| 7| 7| 7| 5| 7| 7| 6| 7| 4| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 5| 3| 3| 5| 9| 3| 3| 3| 2| 3| 3| 3| 3| 6| 1| 3| 3| 3| 5| 3| 3| 3| 3|             
                                           | 3| 3| 6| 4| 5| 6| 2| 3| 5| 3| 8| 4| 4| 5| 3| 7| 1| 4| 5| 3| 6| 5| 3| 0| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    M                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Infiltration Cellular, Histiocyte    |                                                       2                  |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +     +  +     +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +|             
      Congestion, Diffuse                  |                                                    4                     |             
      Giant Cell, Diffuse                  |                                  1                                      1|             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |                   3              2                                       |             
      Hemorrhage, Diffuse                  |                                                                          |             
      Hyperplasia, Lymphoid                |                                                          3               |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |                   4        2  3  2                 4  3                  |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  M     I  M     M  I  M  I  M  M  M  M  I  +  M  +  I  +     +  +  +  +|             
      Cyst                                 |                                                                   X      |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | M  M     M  M     M  M  M  M  I  M  M  M  M  M  M  M  M  M     M  M  M  M|             
                                            __________________________________________________________________________|             
   Skin                                    | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Abscess                              |                                                                          |             
      Cyst                                 |                                                                          |             
      Inflammation, Chronic                |                         3     1                                          |             
      Hair Follicle, Atrophy, Focal        |                                  2                                       |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Coccygeal, Hyperostosis              |                                                                          |             
      Cranium, Inflammation, Chronic       |                      4                                                   |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Demyelination, Multifocal            |                                                                          |             
      Hemorrhage, Focal                    |                   1                                                      |             
      Mineralization, Multifocal           | 1        2  2        1     1     2     1  2        2     2           3  2|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Congestion, Diffuse                  |                                                                          |             
      Hyperplasia, Focal, Adenomatous      |                                              2                           |             
      Infiltration Cellular, Diffuse,      |                                                                          |             
          Histiocyte                       |                                                                          |             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                 1                        |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                      1     1           1     1     1  1  1        2     2|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  40                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 4| 7| 7| 4| 6| 7| 7| 7| 6| 7| 7| 7| 7| 5| 7| 7| 6| 7| 4| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 5| 3| 3| 5| 9| 3| 3| 3| 2| 3| 3| 3| 3| 6| 1| 3| 3| 3| 5| 3| 3| 3| 3|             
                                           | 3| 3| 6| 4| 5| 6| 2| 3| 5| 3| 8| 4| 4| 5| 3| 7| 1| 4| 5| 3| 6| 5| 3| 0| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    M                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM - cont                 |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Foreign Body                         |                      3                                1                  |             
      Inflammation, Acute                  |                                                       2                  |             
      Inflammation, Chronic                |                      4                                                   |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Cyst                                 |    X                                                                     |             
      Hyperplasia, Focal, Tubular          |                                     1                                    |             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                       1                  |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 | 2  1     2        1     1  1  2  2  1  1     1           1     1  1  1  2|             
      Nephropathy, Diffuse                 |                                                                          |             
      Cortex, Degeneration, Diffuse,       |                                                                          |             
          Hyaline                          |                                           2                              |             
      Glomerulus, Inflammation, Diffuse,   |                                                                          |             
           Subacute, Suppurative           |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +|             
      Concretion                           |                   4                                                      |             
      Inflammation, Acute, Diffuse         |                                                                          |             
      Inflammation, Chronic, Diffuse       |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  41                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 3| 5| 7| 7| 7| 4| 7| 7| 7| 7| 4| 7| 7| 7| 7| 4| 7| 7| 7| 4| 4| 7| 7| 6| 7|             
                             DAY ON TEST   | 3| 1| 3| 3| 3| 5| 3| 3| 1| 3| 5| 3| 3| 3| 3| 5| 2| 3| 3| 5| 5| 3| 0| 9| 3|             
                                           | 1| 7| 0| 5| 0| 6| 2| 4| 7| 0| 6| 0| 4| 5| 0| 6| 1| 0| 5| 6| 6| 0| 0| 5| 5|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    M                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
                                            __________________________________________________________________________|             
   Gallbladder                             | A  A  +  +  +     +  +  +  +     +  +  +  +     +  +  M        +  M  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | A  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | A  +  +  +  +     +  +  +  +     +  +  I  +     +  +  +        +  +  +  +|             
      Parasite Metazoan                    |                                                 X                        |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  M  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | A  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  A  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +     +  +  +  +     +  +  +  +     A  +  +        +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | A  M  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  A  +  +|             
      Diverticulum                         |                                                                          |             
      Hyperplasia, Focal, Lymphoid         |                                                                          |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Basophilic Focus                     |             X                                                            |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Multifocal                      |                                                                          |             
      Inclusion Body Intranuclear, Diffuse |                                                                          |             
      Infarct                              |                                                                   2      |             
      Karyomegaly, Diffuse                 |                                                                          |             
      Necrosis, Acute, Focal               |                                                                          |             
      Centrilobular, Fatty Change          |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Atrophy, Focal                       |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                                1  2      |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |             1        1           1        1           1              1  2|             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +           +  +  +  +|             
      Cyst                                 |                                        X                                 |             
      Diverticulum, Focal                  |                                                    2                     |             
      Hyperplasia, Focal, Squamous         |                                                                          |             
      Inflammation, Chronic, Focal         |                                  2                                       |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +           +  M  +  +|             
      Cyst, Focal                          |                                                                          |             
      Cyst Epithelial Inclusion, Focal     |                                                                          |             
      Degeneration, Cystic, Focal          |                                                                          |             
      Erosion, Focal                       |                                                                          |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                  +                                       |             
      Inflammation, Chronic                |                                  4                                       |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  42                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 3| 5| 7| 7| 7| 4| 7| 7| 7| 7| 4| 7| 7| 7| 7| 4| 7| 7| 7| 4| 4| 7| 7| 6| 7|             
                             DAY ON TEST   | 3| 1| 3| 3| 3| 5| 3| 3| 1| 3| 5| 3| 3| 3| 3| 5| 2| 3| 3| 5| 5| 3| 0| 9| 3|             
                                           | 1| 7| 0| 5| 0| 6| 2| 4| 7| 0| 6| 0| 4| 5| 0| 6| 1| 0| 5| 6| 6| 0| 0| 5| 5|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    M                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM - cont              |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Atrium, Thrombosis                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Hyperplasia, Focal                   |                                  3                                       |             
      Hypertrophy, Focal                   |             2                                         1                  |             
      Hypertrophy, Multifocal              |                                        2                                 |             
      Spindle Cell, Hyperplasia, Focal     |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Hyperplasia, Multifocal              |                         3                                                |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Hyperplasia, Focal                   |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | M  M  M  +  M     M  +  +  +     +  +  M  M     +  M  M        M  M  I  M|             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +     +  +  +  +     +  +  +  +     I  +  +        +  +  I  +|             
      Pars Distalis, Cyst                  |                      X                                                   |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Cyst                                 |                                                                          |             
      Follicular Cell, Hyperplasia         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                                          |             
                                            __________________________________________________________________________|             
   Penis                                   |                                                                          |             
      Congestion                           |                                                                          |             
      Inflammation, Chronic                |                                                                          |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |                                                                          |             
      Abscess                              |                                                                          |             
      Inflammation, Chronic                |                                                                          |             
                                            __________________________________________________________________________|             
   Prostate                                | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  M  +  +|             
                                            __________________________________________________________________________|             
   Testes                                  | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Atrophy, Diffuse                     |                                                 4                        |             
      Granuloma Sperm, Focal               |                                                                4         |             
      Mineralization, Focal                |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  M  +  +|             
      Hyperplasia, Lymphoid                |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  43                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 3| 5| 7| 7| 7| 4| 7| 7| 7| 7| 4| 7| 7| 7| 7| 4| 7| 7| 7| 4| 4| 7| 7| 6| 7|             
                             DAY ON TEST   | 3| 1| 3| 3| 3| 5| 3| 3| 1| 3| 5| 3| 3| 3| 3| 5| 2| 3| 3| 5| 5| 3| 0| 9| 3|             
                                           | 1| 7| 0| 5| 0| 6| 2| 4| 7| 0| 6| 0| 4| 5| 0| 6| 1| 0| 5| 6| 6| 0| 0| 5| 5|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    M                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Infiltration Cellular, Histiocyte    |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  M  +  +|             
      Congestion, Diffuse                  |          3                       2                                       |             
      Giant Cell, Diffuse                  |                                           1        2                     |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |                                                                          |             
      Hemorrhage, Diffuse                  |                         4                       4                        |             
      Hyperplasia, Lymphoid                |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |                   4        3                                             |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +  +  +  M     M  +  M  +     +  +  +  M     M  M  +        +  M  +  +|             
      Cyst                                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +  M  M  M  M     M  M  M  M     M  M  M  M     M  M  M        M  M  M  M|             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Abscess                              |    4                                                                     |             
      Cyst                                 |                                                                          |             
      Inflammation, Chronic                |                         3                                                |             
      Hair Follicle, Atrophy, Focal        |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Coccygeal, Hyperostosis              |                                                                          |             
      Cranium, Inflammation, Chronic       |                                                                          |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                   +                                                      |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Demyelination, Multifocal            |                         2                                                |             
      Hemorrhage, Focal                    |                                                                          |             
      Mineralization, Multifocal           |          1  1           1                       1  1  2        1  2  2   |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Congestion, Diffuse                  |                         4                                                |             
      Hyperplasia, Focal, Adenomatous      |             2                                                            |             
      Infiltration Cellular, Diffuse,      |                                                                          |             
          Histiocyte                       |                                                                          |             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |    2  2  2                 1     1  2  1  1        2           2     2   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  44                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 3| 5| 7| 7| 7| 4| 7| 7| 7| 7| 4| 7| 7| 7| 7| 4| 7| 7| 7| 4| 4| 7| 7| 6| 7|             
                             DAY ON TEST   | 3| 1| 3| 3| 3| 5| 3| 3| 1| 3| 5| 3| 3| 3| 3| 5| 2| 3| 3| 5| 5| 3| 0| 9| 3|             
                                           | 1| 7| 0| 5| 0| 6| 2| 4| 7| 0| 6| 0| 4| 5| 0| 6| 1| 0| 5| 6| 6| 0| 0| 5| 5|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    M                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM - cont                 |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Foreign Body                         |          1        2     3                       1  2                     |             
      Inflammation, Acute                  |          1        2                             1  2                     |             
      Inflammation, Chronic                |                         3                                                |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +     +  M  +  +     +  +  +  +     +  +  +        +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |       +                                                                  |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +     +  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Cyst                                 |                                                                          |             
      Hyperplasia, Focal, Tubular          |                                                                          |             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 | 2     2  2  2     2  1  1  3           1  2        1  1        2  2  2  2|             
      Nephropathy, Diffuse                 |                                                 3                        |             
      Cortex, Degeneration, Diffuse,       |                                                                          |             
          Hyaline                          |                                                                          |             
      Glomerulus, Inflammation, Diffuse,   |                                                                          |             
           Subacute, Suppurative           |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +     M  +  +  +     +  +  +  +     +  +  +        +  +  +  +|             
      Concretion                           |    2                                   2                          3      |             
      Inflammation, Acute, Diffuse         |                                                                   4      |             
      Inflammation, Chronic, Diffuse       |    3                                                                     |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  45                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 4| 7| 7| 7| 4| 7| 6| 7| 7|                                            |            |
                             DAY ON TEST   | 3| 5| 3| 3| 2| 5| 3| 1| 3| 3|                                            |            |
                                           | 0| 6| 0| 3| 4| 6| 4| 2| 4| 3|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |      A     |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
    M                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               | +     +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Gallbladder                             | +     +  +  +     +  A  +  M                                             |  41        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +     +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +     +  +  +     +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | +     +  +  +     +  +  +  +                                             |  48        |
      Parasite Metazoan                    |                                                                          |      2     |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +     +  +  +     +  +  +  +                                             |  47        |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +     +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +     +  +  +     +  A  +  +                                             |  47        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +     +  +  +     +  A  +  +                                             |  48        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +     +  +  +     +  A  +  +                                             |  46        |
      Diverticulum                         |                                                                          |      1  4.0|
      Hyperplasia, Focal, Lymphoid         |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Liver                                   | +     +  +  +     +  +  +  +                                             |  50        |
      Basophilic Focus                     | X                                                                        |      3     |
      Hematopoietic Cell Proliferation,    |                                                                          |            |
           Multifocal                      |                                                                          |      1  2.0|
      Inclusion Body Intranuclear, Diffuse |                         3                                                |      1  3.0|
      Infarct                              |                                                                          |      1  2.0|
      Karyomegaly, Diffuse                 |                         3                                                |      1  3.0|
      Necrosis, Acute, Focal               |                                                                          |      2  2.0|
      Centrilobular, Fatty Change          |                         1                                                |      2  1.5|
                                            __________________________________________________________________________|____________|
   Pancreas                                | +     +  +  +     +  +  +  +                                             |  50        |
      Atrophy, Focal                       |                                                                          |      1  1.0|
                                            __________________________________________________________________________|____________|
   Salivary Glands                         | +     +  +  +     +  +  +  +                                             |  50        |
      Infiltration Cellular, Focal,        |                                                                          |            |
          Mononuclear Cell                 |                                                                          |      2  1.5|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |          2                 1                                             |     17  1.3|
                                            __________________________________________________________________________|____________|
   Stomach                                 | +     +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +     +  +  +     +  +  +  +                                             |  49        |
      Cyst                                 |                                                                          |      1     |
      Diverticulum, Focal                  |                                                                          |      1  2.0|
      Hyperplasia, Focal, Squamous         |                         2                                                |      2  2.0|
      Inflammation, Chronic, Focal         |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +     +  +  +     +  +  +  +                                             |  47        |
      Cyst, Focal                          |                                                                          |      1  1.0|
      Cyst Epithelial Inclusion, Focal     |                                                                          |      1  1.0|
      Degeneration, Cystic, Focal          |                         2                                                |      1  2.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  46                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 4| 7| 7| 7| 4| 7| 6| 7| 7|                                            |            |
                             DAY ON TEST   | 3| 5| 3| 3| 2| 5| 3| 1| 3| 3|                                            |            |
                                           | 0| 6| 0| 3| 4| 6| 4| 2| 4| 3|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |      A     |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
    M                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
      Erosion, Focal                       |             3                                                            |      1  3.0|
                                            __________________________________________________________________________|____________|
   Tooth                                   |                                                                          |   6        |
      Inflammation, Chronic                |                                                                          |      6  3.2|
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Heart                                   | +     +  +  +     +  +  +  +                                             |  50        |
      Atrium, Thrombosis                   |                         X                                                |      1     |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +     +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   |       +  +  +     +  +  +  +                                             |  49        |
      Hyperplasia, Focal                   |       2                                                                  |      3  2.3|
      Hypertrophy, Focal                   |                         3                                                |      5  1.6|
      Hypertrophy, Multifocal              |                                                                          |      1  2.0|
      Spindle Cell, Hyperplasia, Focal     |          3                                                               |      1  3.0|
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  |       +  +  +     +  +  +  +                                             |  47        |
      Hyperplasia, Multifocal              |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      | +     +  +  +     +  +  +  +                                             |  50        |
      Hyperplasia, Focal                   |                                                                          |      3  2.7|
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | M     +  M  +     +  M  M  +                                             |  20        |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +     M  +  +     +  +  +  +                                             |  45        |
      Pars Distalis, Cyst                  |                                                                          |      2     |
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | +     +  +  +     +  +  +  +                                             |  49        |
      Cyst                                 |                                                                          |      1     |
      Follicular Cell, Hyperplasia         |          2                                                               |      1  2.0|
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Epididymis                              | +     +  +  +     +  +  +  +                                             |  50        |
      Infiltration Cellular, Focal,        |                                                                          |            |
          Mononuclear Cell                 |                                                                          |      1  1.0|
                                            __________________________________________________________________________|____________|
   Penis                                   |                                                                          |   1        |
      Congestion                           |                                                                          |      1  3.0|
      Inflammation, Chronic                |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Preputial Gland                         |                                                                          |   2        |
      Abscess                              |                                                                          |      1  4.0|
      Inflammation, Chronic                |                                                                          |      1  3.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  47                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 4| 7| 7| 7| 4| 7| 6| 7| 7|                                            |            |
                             DAY ON TEST   | 3| 5| 3| 3| 2| 5| 3| 1| 3| 3|                                            |            |
                                           | 0| 6| 0| 3| 4| 6| 4| 2| 4| 3|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |      A     |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
    M                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 GENITAL SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Prostate                                | +     +  +  +     +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Testes                                  | +     +  +  +     +  +  +  +                                             |  50        |
      Atrophy, Diffuse                     |                                                                          |      1  4.0|
      Granuloma Sperm, Focal               |                                                                          |      1  4.0|
      Mineralization, Focal                |                                                                          |      2  1.0|
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             | +     +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Lymph Node                              | +     +  +  +     +  +  +  +                                             |  49        |
      Hyperplasia, Lymphoid                |                                                                          |      1  2.0|
      Infiltration Cellular, Histiocyte    |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  | +     +  +  +     +  +  +  +                                             |  48        |
      Congestion, Diffuse                  |       2                 3                                                |      5  2.8|
      Giant Cell, Diffuse                  | 2                       2                                                |      6  1.5|
      Hematopoietic Cell Proliferation,    |                                                                          |            |
           Diffuse                         |                                                                          |      2  2.5|
      Hemorrhage, Diffuse                  |                                                                          |      2  4.0|
      Hyperplasia, Lymphoid                |                            4                                             |      2  3.5|
                                            __________________________________________________________________________|____________|
   Spleen                                  | +     +  M  +     +  +  +  +                                             |  49        |
      Hematopoietic Cell Proliferation,    |                                                                          |            |
           Diffuse                         |             3              4                                             |     10  3.2|
                                            __________________________________________________________________________|____________|
   Thymus                                  | +     +  M  M     +  M  M  M                                             |  24        |
      Cyst                                 | X                                                                        |      2     |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           | M     M  M  M     M  I  M  M                                             |   1        |
                                            __________________________________________________________________________|____________|
   Skin                                    | +     M  +  +     +  +  +  +                                             |  49        |
      Abscess                              |                                                                          |      1  4.0|
      Cyst                                 |                            X                                             |      1     |
      Inflammation, Chronic                |          3        4        3                                             |      6  2.8|
      Hair Follicle, Atrophy, Focal        |                                                                          |      1  2.0|
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    | +     +  +  +     +  +  +  +                                             |  50        |
      Coccygeal, Hyperostosis              |       2                                                                  |      1  2.0|
      Cranium, Inflammation, Chronic       |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Skeletal Muscle                         |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  48                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 4| 7| 7| 7| 4| 7| 6| 7| 7|                                            |            |
                             DAY ON TEST   | 3| 5| 3| 3| 2| 5| 3| 1| 3| 3|                                            |            |
                                           | 0| 6| 0| 3| 4| 6| 4| 2| 4| 3|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |      A     |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
    M                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 NERVOUS SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   | +     +  +  +     +  +  +  +                                             |  50        |
      Demyelination, Multifocal            |                                                                          |      1  2.0|
      Hemorrhage, Focal                    |                                                                          |      1  1.0|
      Mineralization, Multifocal           |       1  2        1                                                      |     24  1.5|
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    | +     +  +  +     +  +  +  +                                             |  50        |
      Congestion, Diffuse                  |                      3                                                   |      2  3.5|
      Hyperplasia, Focal, Adenomatous      | 2                 1                                                      |      4  1.8|
      Infiltration Cellular, Diffuse,      |                                                                          |            |
          Histiocyte                       |                         2                                                |      1  2.0|
      Infiltration Cellular, Focal,        |                                                                          |            |
          Mononuclear Cell                 |                                                                          |      1  1.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 | 1        1        1     2  1                                             |     25  1.4|
                                            __________________________________________________________________________|____________|
   Nose                                    | +     +  +  +     +  +  +  +                                             |  50        |
      Foreign Body                         |       1                                                                  |      8  1.8|
      Inflammation, Acute                  |       2                                                                  |      6  1.7|
      Inflammation, Chronic                |                                                                          |      2  3.5|
                                            __________________________________________________________________________|____________|
   Trachea                                 | +     M  +  +     M  +  +  M                                             |  46        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Harderian Gland                         |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +     +  +  +     +  +  +  +                                             |  50        |
      Cyst                                 |                         X                                                |      2     |
      Hyperplasia, Focal, Tubular          |                                                                          |      1  1.0|
      Infiltration Cellular, Focal,        |                                                                          |            |
          Mononuclear Cell                 |                                                                          |      1  1.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 | 1     1  3  3     1     1  3                                             |     39  1.6|
      Nephropathy, Diffuse                 |                                                                          |      1  3.0|
      Cortex, Degeneration, Diffuse,       |                                                                          |            |
          Hyaline                          |                                                                          |      1  2.0|
      Glomerulus, Inflammation, Diffuse,   |                                                                          |            |
           Subacute, Suppurative           |             3                                                            |      1  3.0|
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +     +  +  +     +  +  +  +                                             |  49        |
      Concretion                           | 2                       3                                                |      6  2.7|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  49                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 4| 7| 7| 7| 4| 7| 6| 7| 7|                                            |            |
                             DAY ON TEST   | 3| 5| 3| 3| 2| 5| 3| 1| 3| 3|                                            |            |
                                           | 0| 6| 0| 3| 4| 6| 4| 2| 4| 3|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |      A     |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
    M                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 URINARY SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
      Inflammation, Acute, Diffuse         |                                                                          |      1  4.0|
      Inflammation, Chronic, Diffuse       |                                                                          |      1  3.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  50                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 7| 7| 7| 7| 7| 7| 6| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 4| 4| 7| 7| 6|             
                             DAY ON TEST   | 5| 3| 3| 3| 3| 3| 3| 3| 3| 6| 5| 3| 3| 3| 3| 1| 3| 3| 3| 3| 5| 5| 3| 3| 2|             
                                           | 6| 4| 4| 3| 3| 0| 0| 0| 5| 4| 6| 0| 3| 4| 3| 6| 5| 3| 0| 3| 6| 6| 3| 3| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    112MG/KG                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small                         |             +     +                                                  +   |             
      Diverticulum                         |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               |             +                                                        +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  |             +                                                        +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                |             +     +                                                  +   |             
      Diverticulum                         |             4                                                        4   |             
                                            __________________________________________________________________________|             
   Liver                                   |          +     +  +                                +  +                  |             
      Infarct                              |                2                                                         |             
      Mixed Cell Focus                     |                   X                                                      |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |                                                       +                  |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |                                                       +                  |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |                                                                          |             
      Abscess                              |                                                                          |             
                                            __________________________________________________________________________|             
   Testes                                  |                                                                          |             
      Atrophy, Diffuse                     |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              |    +        +                                +                       +   |             
      Congestion                           |                                                                          |             
      Pigmentation                         |                                                                          |             
      Thoracic, Angiectasis                |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |    +        +                                                        +   |             
                                            __________________________________________________________________________|             
   Spleen                                  |                                  +                    +                  |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |                                                       4                  |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    |    +                                      +  +  +                        |             
      Inflammation, Chronic                |                                           4                              |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                              +                           |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  51                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 7| 7| 7| 7| 7| 7| 6| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 4| 4| 7| 7| 6|             
                             DAY ON TEST   | 5| 3| 3| 3| 3| 3| 3| 3| 3| 6| 5| 3| 3| 3| 3| 1| 3| 3| 3| 3| 5| 5| 3| 3| 2|             
                                           | 6| 4| 4| 3| 3| 0| 0| 0| 5| 4| 6| 0| 3| 4| 3| 6| 5| 3| 0| 3| 6| 6| 3| 3| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    112MG/KG                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |                                  +           +                           |             
      Hyperplasia, Focal, Adenomatous      |                                  2                                       |             
                                            __________________________________________________________________________|             
   Trachea                                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  |                                                                      +   |             
      Proximal Convoluted Renal Tubule,    |                                                                          |             
           Dilatation, Diffuse             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  52                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 6| 7| 6| 7| 7| 6| 7| 4| 4| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 3| 3| 5| 3| 3| 3| 3| 3| 3| 3| 8| 3| 5| 3| 3| 9| 1| 5| 5| 3| 3| 3|             
                                           | 5| 5| 4| 3| 4| 6| 5| 4| 0| 5| 4| 0| 5| 6| 0| 1| 0| 4| 8| 5| 6| 6| 4| 0| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    112MG/KG                               | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small                         |                                  +  +                                    |             
      Diverticulum                         |                                     4                                    |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                |                                  +                                       |             
      Diverticulum                         |                                  4                                       |             
                                            __________________________________________________________________________|             
   Liver                                   | +                    +  +        +     +        +  +  +           +      |             
      Infarct                              |                                                                          |             
      Mixed Cell Focus                     |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |                                                       +                  |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |                                                                          |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +                                                                        |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |                      +                                                   |             
      Abscess                              |                      3                                                   |             
                                            __________________________________________________________________________|             
   Testes                                  |                                                                          |             
      Atrophy, Diffuse                     |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              |                                  +  +                    +               |             
      Congestion                           |                                                          2               |             
      Pigmentation                         |                                                                          |             
      Thoracic, Angiectasis                |                                                          3               |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |                                  +  +                                    |             
                                            __________________________________________________________________________|             
   Spleen                                  |                                              +           +               |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |                                              4           4               |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    |                                              +     +     +               |             
      Inflammation, Chronic                |                                                    4                     |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                              +        +                  |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  53                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 6| 7| 6| 7| 7| 6| 7| 4| 4| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 3| 3| 5| 3| 3| 3| 3| 3| 3| 3| 8| 3| 5| 3| 3| 9| 1| 5| 5| 3| 3| 3|             
                                           | 5| 5| 4| 3| 4| 6| 5| 4| 0| 5| 4| 0| 5| 6| 0| 1| 0| 4| 8| 5| 6| 6| 4| 0| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    112MG/KG                               | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |    +                 +                 +              +                  |             
      Hyperplasia, Focal, Adenomatous      |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 |                                                       +                  |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |       +                                                                  |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  |                                                       +  +               |             
      Proximal Convoluted Renal Tubule,    |                                                                          |             
           Dilatation, Diffuse             |                                                          3               |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  54                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 4| 4| 4| 7| 7|                                            |            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 5| 5| 5| 3| 3|                                            |            |
                                           | 3| 4| 5| 4| 3| 6| 6| 6| 5| 5|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|                                            |      A     |
    112MG/KG                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      L     |
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Intestine Small                         |                                                                          |   5        |
      Diverticulum                         |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               |                                                                          |   2        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  |                                                                          |   2        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                |                                                                          |   4        |
      Diverticulum                         |                                                                          |      3  4.0|
                                            __________________________________________________________________________|____________|
   Liver                                   |    +     +                                                               |  16        |
      Infarct                              |                                                                          |      1  2.0|
      Mixed Cell Focus                     |                                                                          |      1     |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Heart                                   |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Preputial Gland                         |    +     +                                                               |   3        |
      Abscess                              |    4     4                                                               |      3  3.7|
                                            __________________________________________________________________________|____________|
   Testes                                  |          +                                                               |   1        |
      Atrophy, Diffuse                     |          3                                                               |      1  3.0|
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lymph Node                              |                         +                                                |   8        |
      Congestion                           |                                                                          |      1  2.0|
      Pigmentation                         |                         2                                                |      1  2.0|
      Thoracic, Angiectasis                |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  |                                                                          |   5        |
                                            __________________________________________________________________________|____________|
   Spleen                                  |                                                                          |   4        |
      Hematopoietic Cell Proliferation,    |                                                                          |            |
           Diffuse                         |                                                                          |      3  4.0|
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Skin                                    |    +                    +                                                |   9        |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  55                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 4| 4| 4| 7| 7|                                            |            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 5| 5| 5| 3| 3|                                            |            |
                                           | 3| 4| 5| 4| 3| 6| 6| 6| 5| 5|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|                                            |      A     |
    112MG/KG                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      L     |
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 INTEGUMENTARY SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
      Inflammation, Chronic                |    4                                                                     |      3  4.0|
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Skeletal Muscle                         |                                                                          |   3        |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    | +                                                                        |   7        |
      Hyperplasia, Focal, Adenomatous      |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Trachea                                 |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Harderian Gland                         |             +                                                            |   2        |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  |                                                                          |   3        |
      Proximal Convoluted Renal Tubule,    |                                                                          |            |
           Dilatation, Diffuse             |                                                                          |      1  3.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  56                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 4| 6| 7| 7| 4| 7| 7| 5| 7| 1| 2| 4| 7| 7| 1| 4| 7| 6| 7| 4| 7| 7| 7| 7|             
                             DAY ON TEST   | 2| 5| 4| 3| 3| 5| 3| 3| 7| 3| 3| 0| 5| 3| 3| 4| 5| 3| 2| 3| 5| 3| 3| 3| 3|             
                                           | 9| 6| 1| 0| 4| 6| 4| 0| 4| 0| 3| 9| 6| 5| 4| 0| 6| 4| 8| 5| 6| 3| 3| 3| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
      Serosa, Inflammation, Subacute       |                                                                          |             
                                            __________________________________________________________________________|             
   Gallbladder                             | +     +  +  +     +  +  +  +  +  A     +  +  A     +  A  +     +  I  I  +|             
      Cyst                                 |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large                         | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +     +  +  +     +  +  +  +  +  +     +  +  A     +  +  +     +  +  +  +|             
      Parasite Metazoan                    |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +     +  +  +     +  +  +  +  +  +     +  +  A     +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +     +  +  +     +  +  +  +  +  +     +  +  +     +  I  +     +  +  +  +|             
      Inflammation, Acute, Focal           |       2                                                                  |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +     +  +  +     +  +  +  +  +  A     +  +  A     +  +  +     +  +  +  +|             
      Amyloid Deposition, Chronic, Diffuse |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +     +  +  +     +  +  +  +  +  A     +  +  A     +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +     +  +  +     +  +  +  +  +  A     +  +  A     +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Liver                                   | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
      Basophilic Focus                     |                                                                          |             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                                1         |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                                                          |             
      Mixed Cell Focus                     |                                                                          |             
      Necrosis, Acute, Multifocal          |                                                       2                  |             
      Centrilobular, Fatty Change          |                                                                          |             
      Centrilobular, Necrosis, Acute,      |                                                                          |             
          Diffuse                          |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
      Edema, Acute, Diffuse                |                                                                          |             
      Hyperplasia, Focal, Glandular        |                                                                          |             
      Inflammation, Chronic, Multifocal    |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                       1                  |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |             2              1                             2     2        1|             
                                            __________________________________________________________________________|             
   Stomach                                 | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +     +  +  +     +  +  +  +  +  +     +  +  M     +  +  +     +  +  +  +|             
      Cyst Epithelial Inclusion            |                                           X                              |             
      Hyperplasia, Focal, Squamous         |                                                                          |             
      Inflammation, Chronic, Focal         |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +     +  +  +     +  +  +  +  +  +     +  +  M     +  +  +     +  +  +  +|             
      Edema, Diffuse                       |                                                                          |             
      Hyperplasia, Focal                   |                                                    3                     |             
      Hyperplasia, Adenomatous             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  57                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 4| 6| 7| 7| 4| 7| 7| 5| 7| 1| 2| 4| 7| 7| 1| 4| 7| 6| 7| 4| 7| 7| 7| 7|             
                             DAY ON TEST   | 2| 5| 4| 3| 3| 5| 3| 3| 7| 3| 3| 0| 5| 3| 3| 4| 5| 3| 2| 3| 5| 3| 3| 3| 3|             
                                           | 9| 6| 1| 0| 4| 6| 4| 0| 4| 0| 3| 9| 6| 5| 4| 0| 6| 4| 8| 5| 6| 3| 3| 3| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Tooth                                   |             +                                                            |             
      Inflammation, Chronic                |             3                                                            |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                                          |             
      Inflammation, Chronic, Focal         |             2                                                            |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
      Cytoplasmic Alteration, Focal        |                   2                                                      |             
      Hyperplasia, Focal                   |                                                                          |             
      Hypertrophy, Focal                   |       2                                1                                 |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +     +  +  +     +  +  +  +  +  +     +  +  +     +  I  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +     M  +  M     M  +  M  +  M  +     +  M  M     +  +  +     +  M  M  +|             
      Cyst                                 |                                                                X         |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
      Pars Distalis, Cyst                  |          X           X                                                   |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
      Depletion Secretory                  |                                                                          |             
      Hemorrhage, Acute, Focal             |                                                                          |             
      Inflammation, Subacute               |                                                                          |             
      C-Cell, Hyperplasia, Chronic, Focal  |                                                                          |             
      Follicular Cell, Hyperplasia         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Penis                                   |                                                                          |             
      Congestion                           |                                                                          |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |                                                                          |             
      Abscess                              |                                                                          |             
      Inflammation, Chronic                |                                                                          |             
                                            __________________________________________________________________________|             
   Prostate                                | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
      Dilatation                           |                                                                          |             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         |                                                                          |             
      Dilatation                           |                                                                          |             
      Inflammation, Chronic, Diffuse       |                                                                          |             
                                            __________________________________________________________________________|             
   Testes                                  | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  58                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 4| 6| 7| 7| 4| 7| 7| 5| 7| 1| 2| 4| 7| 7| 1| 4| 7| 6| 7| 4| 7| 7| 7| 7|             
                             DAY ON TEST   | 2| 5| 4| 3| 3| 5| 3| 3| 7| 3| 3| 0| 5| 3| 3| 4| 5| 3| 2| 3| 5| 3| 3| 3| 3|             
                                           | 9| 6| 1| 0| 4| 6| 4| 0| 4| 0| 3| 9| 6| 5| 4| 0| 6| 4| 8| 5| 6| 3| 3| 3| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Atrophy, Diffuse                     |                                                                          |             
      Degeneration, Diffuse                |       4                                                                  |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Lymph Node                              | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |                                                                          |             
      Thrombosis                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
      Ectasia, Diffuse                     |                                                                          |             
      Giant Cell, Diffuse                  |                                                                      3   |             
      Hyperplasia, Diffuse, Re Cell        |                            3                                             |             
                                            __________________________________________________________________________|             
   Spleen                                  | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |                                                    4  4                  |             
      Hyperplasia, Lymphoid                |                                                                          |             
                                            __________________________________________________________________________|             
   Thymus                                  | +     +  M  +     +  +  +  +  +  +     M  +  M     M  M  +     +  +  M  +|             
      Atrophy, Diffuse                     |       4                                                                  |             
      Cyst                                 | X                                                                        |             
      Mediastinum, Inflammation, Acute     |                                                                          |             
      Medulla, Hyperplasia, Focal, Lymphoid|                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | M     M  M  M     +  M  M  M  M  M     M  M  M     M  M  M     M  M  M  M|             
                                            __________________________________________________________________________|             
   Skin                                    | +     +  +  +     +  +  +  +  +  +     +  +  I     +  +  +     +  +  +  +|             
      Edema, Acute, Diffuse                |                                                                          |             
      Inflammation, Chronic                |                                  1                 3                     |             
      Inflammation, Subacute               |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
      Cartilage, Proliferation, Chronic,   |                                                                          |             
           Focal                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
      Hydrocephalus                        |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                                                          |             
      Mineralization, Multifocal           | 1     2              2  1              1  1        2     1     1         |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  59                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 4| 6| 7| 7| 4| 7| 7| 5| 7| 1| 2| 4| 7| 7| 1| 4| 7| 6| 7| 4| 7| 7| 7| 7|             
                             DAY ON TEST   | 2| 5| 4| 3| 3| 5| 3| 3| 7| 3| 3| 0| 5| 3| 3| 4| 5| 3| 2| 3| 5| 3| 3| 3| 3|             
                                           | 9| 6| 1| 0| 4| 6| 4| 0| 4| 0| 3| 9| 6| 5| 4| 0| 6| 4| 8| 5| 6| 3| 3| 3| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM - cont                 |                                                                          |             
                                           |                                                                          |             
      Congestion, Diffuse                  |                         3                                                |             
      Hemorrhage, Focal                    |                   1                                                      |             
      Hemorrhage, Multifocal               |                                                                          |             
      Hyperplasia, Focal, Adenomatous      |                            1                                             |             
      Infiltration Cellular, Diffuse,      |                                                                          |             
          Histiocyte                       |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 | 1        1           1     1           1                 2     1  2  2  1|             
      Infiltration Cellular, Multifocal,   |                                                                          |             
           Histiocyte                      |                                                                          |             
      Inflammation, Chronic                |                                                                          |             
      Pleura, Inflammation, Subacute       |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
      Foreign Body                         |                                                          1               |             
      Hyperplasia, Focal, Glandular        |                                                                2         |             
      Inflammation, Acute                  |       1                                                                  |             
                                            __________________________________________________________________________|             
   Trachea                                 | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +     +  +  +     +  +  +  +  +  +     +  +  +     +  +  +     +  +  +  +|             
      Cyst                                 |                      X                                                   |             
      Ectopic Tissue                       |                                                                          |             
      Hyperplasia, Focal, Tubular          |                            1                                             |             
      Hyperplasia, Multifocal, Tubular     |             3                                                            |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |          1  1     1  1  1  1           2  1        1  1  1        1  1  1|             
      Inflammation, Chronic                |                                                                          |             
      Nephropathy, Diffuse                 |                                                       3                  |             
      Vacuolization Cytoplasmic, Multifocal| 1                                                                        |             
      Cortex, Degeneration, Diffuse,       |                                                                          |             
          Hyaline                          |                                                                          |             
      Cortex, Vacuolization Cytoplasmic,   |                                                                          |             
           Multifocal                      |                                                                          |             
      Glomerulus, Amyloid Deposition,      |                                                                          |             
          Diffuse                          |                                                                          |             
      Proximal Convoluted Renal Tubule,    |                                                                          |             
           Degeneration, Focal             |                                                                         2|             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +     +  +  +     +  +  +  +  +  A     +  +  A     +  +  +     +  +  +  +|             
      Concretion                           |                                           2                              |             
      Edema, Acute, Diffuse                |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  60                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 6| 7| 7| 7| 1| 6| 7| 7| 7| 4| 4| 7| 7| 7| 3| 5| 4| 7| 7| 0| 2| 4| 7| 7|             
                             DAY ON TEST   | 5| 5| 3| 3| 3| 4| 7| 0| 3| 3| 5| 5| 3| 3| 3| 1| 9| 5| 3| 3| 0| 4| 5| 3| 3|             
                                           | 6| 3| 3| 3| 3| 1| 9| 8| 3| 4| 6| 6| 5| 4| 0| 0| 0| 6| 0| 0| 6| 1| 6| 5| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |    +  +  +  I  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
      Serosa, Inflammation, Subacute       |                                                             3            |             
                                            __________________________________________________________________________|             
   Gallbladder                             |    +  +  +  M  A  A  +  +  +        +  +  +  +  A     +  +  +  A     +  +|             
      Cyst                                 |                                                          X               |             
                                            __________________________________________________________________________|             
   Intestine Large                         |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |    +  +  +  +  A  M  A  +  +        +  +  +  +  +     +  +  +  +     +  +|             
      Parasite Metazoan                    |                            X                                             |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |    +  +  +  +  A  M  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
      Inflammation, Acute, Focal           |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small                         |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               |    +  +  +  +  A  +  +  +  +        +  +  +     A     +  +  +  A     +  +|             
      Amyloid Deposition, Chronic, Diffuse |                            2                                             |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  |    +  +  +  +  A  +  +  +  +        +  +  +     A     +  +  +  M     +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                |    +  +  +  +  A  +  +  +  +        +  +  +     A     +  +  +  A     +  +|             
                                            __________________________________________________________________________|             
   Liver                                   |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
      Basophilic Focus                     |                                                       X                  |             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                     1                                    |             
      Mixed Cell Focus                     |                   X                                                      |             
      Necrosis, Acute, Multifocal          |                                                                          |             
      Centrilobular, Fatty Change          |                1     2                                                   |             
      Centrilobular, Necrosis, Acute,      |                                                                          |             
          Diffuse                          |                   4                                                      |             
                                            __________________________________________________________________________|             
   Pancreas                                |    +  +  +  +  +  +  +  +  +        +  +  M  +  M     +  +  +  +     +  +|             
      Edema, Acute, Diffuse                |                      3                                                   |             
      Hyperplasia, Focal, Glandular        |                                              2                           |             
      Inflammation, Chronic, Multifocal    |                      2                                                   |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |       1                 2  2                    1     1  1              1|             
                                            __________________________________________________________________________|             
   Stomach                                 |    +  +  +  +  +  +  +  +  +        +  +  M  +  +     +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    |    +  +  +  +  +  +     +  +        +  +  M     +     +  +  +  +     +  +|             
      Cyst Epithelial Inclusion            |                                                                         X|             
      Hyperplasia, Focal, Squamous         |          3                             2                                 |             
      Inflammation, Chronic, Focal         |                                                       2                  |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      |    +  +  +  +  +  +  +  +  +        +  +  M     +     +  +  +  +     +  +|             
      Edema, Diffuse                       |                      3                                                   |             
      Hyperplasia, Focal                   |                                                                          |             
      Hyperplasia, Adenomatous             |          3                                                               |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  61                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 6| 7| 7| 7| 1| 6| 7| 7| 7| 4| 4| 7| 7| 7| 3| 5| 4| 7| 7| 0| 2| 4| 7| 7|             
                             DAY ON TEST   | 5| 5| 3| 3| 3| 4| 7| 0| 3| 3| 5| 5| 3| 3| 3| 1| 9| 5| 3| 3| 0| 4| 5| 3| 3|             
                                           | 6| 3| 3| 3| 3| 1| 9| 8| 3| 4| 6| 6| 5| 4| 0| 0| 0| 6| 0| 0| 6| 1| 6| 5| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                                                          |             
      Inflammation, Chronic                |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
      Infiltration Cellular, Focal,        |                                                                          |             
          Mononuclear Cell                 |                                                                          |             
      Inflammation, Chronic, Focal         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |    +  +  +  +  +  +  +  +  +        +  +  +     +     +  +  +  +     +  +|             
      Cytoplasmic Alteration, Focal        |                                                                          |             
      Hyperplasia, Focal                   |                                                                          |             
      Hypertrophy, Focal                   |                      2                          2     2                  |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  |    +  +  +  +  +  +  +  +  +        +  +  +     +     +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |    +  +  +  +  +  +  +  +  +        +  +  M  +  M     +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       |    +  +  +  +  +  +  +  M  +        +  +  +  M  M     M  +  M  M     M  M|             
      Cyst                                 |                                                                          |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
      Pars Distalis, Cyst                  |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
      Depletion Secretory                  |                                     X                                    |             
      Hemorrhage, Acute, Focal             |                                                             2            |             
      Inflammation, Subacute               |                                                             3            |             
      C-Cell, Hyperplasia, Chronic, Focal  |                                                                          |             
      Follicular Cell, Hyperplasia         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Penis                                   |       +                                                                  |             
      Congestion                           |       3                                                                  |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |                                              +                           |             
      Abscess                              |                                              4                           |             
      Inflammation, Chronic                |                                                                          |             
                                            __________________________________________________________________________|             
   Prostate                                |    +  +  +  +  +  +     +  M        +  +  +  +  +     +  +  +  +     +  +|             
      Dilatation                           |                                                 3                        |             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         |                                                 +        +               |             
      Dilatation                           |                                                 4        4               |             
      Inflammation, Chronic, Diffuse       |                                                          3               |             
                                            __________________________________________________________________________|             
   Testes                                  |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  62                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 6| 7| 7| 7| 1| 6| 7| 7| 7| 4| 4| 7| 7| 7| 3| 5| 4| 7| 7| 0| 2| 4| 7| 7|             
                             DAY ON TEST   | 5| 5| 3| 3| 3| 4| 7| 0| 3| 3| 5| 5| 3| 3| 3| 1| 9| 5| 3| 3| 0| 4| 5| 3| 3|             
                                           | 6| 3| 3| 3| 3| 1| 9| 8| 3| 4| 6| 6| 5| 4| 0| 0| 0| 6| 0| 0| 6| 1| 6| 5| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Atrophy, Diffuse                     |                      4                                                   |             
      Degeneration, Diffuse                |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Lymph Node                              |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |                      3                                                   |             
      Thrombosis                           |                      X                                                   |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
      Ectasia, Diffuse                     |                                     2                                    |             
      Giant Cell, Diffuse                  |                                     3                                    |             
      Hyperplasia, Diffuse, Re Cell        |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Diffuse                         |    4                                3                                    |             
      Hyperplasia, Lymphoid                |    3        3                             3                              |             
                                            __________________________________________________________________________|             
   Thymus                                  |    M  +  +  M  I  M  I  M  +        +  +  +  +  +     M  +  +  +     +  +|             
      Atrophy, Diffuse                     |                                                                          |             
      Cyst                                 |                                                                          |             
      Mediastinum, Inflammation, Acute     |                                                             3            |             
      Medulla, Hyperplasia, Focal, Lymphoid|                            3                                             |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |    M  M  M  M  M  M  M  M  M        M  M  M  M  M     M  M  M  M     M  M|             
                                            __________________________________________________________________________|             
   Skin                                    |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
      Edema, Acute, Diffuse                |                      4                                                   |             
      Inflammation, Chronic                |       3                                                                  |             
      Inflammation, Subacute               |                      2                                                   |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
      Cartilage, Proliferation, Chronic,   |                                                                          |             
           Focal                           |       3                                                                  |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
      Hydrocephalus                        |                      2                                                   |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                           2                              |             
      Mineralization, Multifocal           |    2  2           1  2  2                 2           1              1  2|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  63                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 6| 7| 7| 7| 1| 6| 7| 7| 7| 4| 4| 7| 7| 7| 3| 5| 4| 7| 7| 0| 2| 4| 7| 7|             
                             DAY ON TEST   | 5| 5| 3| 3| 3| 4| 7| 0| 3| 3| 5| 5| 3| 3| 3| 1| 9| 5| 3| 3| 0| 4| 5| 3| 3|             
                                           | 6| 3| 3| 3| 3| 1| 9| 8| 3| 4| 6| 6| 5| 4| 0| 0| 0| 6| 0| 0| 6| 1| 6| 5| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM - cont                 |                                                                          |             
                                           |                                                                          |             
      Congestion, Diffuse                  |                3                                4           3            |             
      Hemorrhage, Focal                    |                                                                          |             
      Hemorrhage, Multifocal               |                                              2                           |             
      Hyperplasia, Focal, Adenomatous      |                                                                          |             
      Infiltration Cellular, Diffuse,      |                                                                          |             
          Histiocyte                       |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |       2              1     2        1  2  2           1  2           1  2|             
      Infiltration Cellular, Multifocal,   |                                                                          |             
           Histiocyte                      |             2                                                            |             
      Inflammation, Chronic                |       1                                                                  |             
      Pleura, Inflammation, Subacute       |                                                             2            |             
                                            __________________________________________________________________________|             
   Nose                                    |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
      Foreign Body                         |                                                                          |             
      Hyperplasia, Focal, Glandular        |                                                                          |             
      Inflammation, Acute                  |                3                                                         |             
                                            __________________________________________________________________________|             
   Trachea                                 |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
      Cyst                                 |                      X                                X  X               |             
      Ectopic Tissue                       |             X                                                            |             
      Hyperplasia, Focal, Tubular          |                                                                          |             
      Hyperplasia, Multifocal, Tubular     |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |       2  1  1     2  2     2        3     1  1  1     2  1              2|             
      Inflammation, Chronic                |    4                                                                     |             
      Nephropathy, Diffuse                 |                      3  3                                                |             
      Vacuolization Cytoplasmic, Multifocal|                                                                          |             
      Cortex, Degeneration, Diffuse,       |                                                                          |             
          Hyaline                          |                3                                                         |             
      Cortex, Vacuolization Cytoplasmic,   |                                                                          |             
           Multifocal                      |                                                 2                        |             
      Glomerulus, Amyloid Deposition,      |                                                                          |             
          Diffuse                          |                            2                                             |             
      Proximal Convoluted Renal Tubule,    |                                                                          |             
           Degeneration, Focal             |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         |    +  +  +  +  +  +  +  +  +        +  +  +  +  +     +  +  +  +     +  +|             
      Concretion                           |                                                             2            |             
      Edema, Acute, Diffuse                |                      4                                                   |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  64                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 0| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 1| 3| 3| 3| 3|                                            |            |
                                           | 5| 0| 4| 0| 5| 5| 3| 0| 5| 5|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      A     |
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|                                            |      L     |
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +  +  +  +  +  +  +                                             |  49        |
      Serosa, Inflammation, Subacute       |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Gallbladder                             | +  +  +  +  +  A  +  +  +  +                                             |  39        |
      Cyst                                 |                                                                          |      1     |
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +  +  +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  +  +  +  A  +  +  +  +                                             |  45        |
      Parasite Metazoan                    |                                                                          |      1     |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +                                             |  47        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +  +                                             |  49        |
      Inflammation, Acute, Focal           |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +  +  +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +  +  +  A  +  +  +  +                                             |  43        |
      Amyloid Deposition, Chronic, Diffuse |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  +  +  A  +  +  +  +                                             |  43        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  +  +  A  +  +  +  +                                             |  43        |
                                            __________________________________________________________________________|____________|
   Liver                                   | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Basophilic Focus                     |                                                                          |      1     |
      Infiltration Cellular, Focal,        |                                                                          |            |
          Mononuclear Cell                 |                                                                          |      1  1.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |                                                                          |      1  1.0|
      Mixed Cell Focus                     |                         X                                                |      2     |
      Necrosis, Acute, Multifocal          |                                                                          |      1  2.0|
      Centrilobular, Fatty Change          |                                                                          |      2  1.5|
      Centrilobular, Necrosis, Acute,      |                                                                          |            |
          Diffuse                          |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +  +  +  +  +  +  +                                             |  48        |
      Edema, Acute, Diffuse                |                                                                          |      1  3.0|
      Hyperplasia, Focal, Glandular        |                                                                          |      1  2.0|
      Inflammation, Chronic, Multifocal    |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Infiltration Cellular, Focal,        |                                                                          |            |
          Mononuclear Cell                 |                                                                          |      1  1.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |             1     1  3     1                                             |     16  1.4|
                                            __________________________________________________________________________|____________|
   Stomach                                 | +  +  +  +  +  +  +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +                                             |  46        |
      Cyst Epithelial Inclusion            |                                                                          |      2     |
      Hyperplasia, Focal, Squamous         |                                                                          |      2  2.5|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  65                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 0| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 1| 3| 3| 3| 3|                                            |            |
                                           | 5| 0| 4| 0| 5| 5| 3| 0| 5| 5|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      A     |
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|                                            |      L     |
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
      Inflammation, Chronic, Focal         |       2                                                                  |      2  2.0|
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +  +                                             |  47        |
      Edema, Diffuse                       |                                                                          |      1  3.0|
      Hyperplasia, Focal                   |                                                                          |      1  3.0|
      Hyperplasia, Adenomatous             |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Tooth                                   |                                                                          |   1        |
      Inflammation, Chronic                |                                                                          |      1  3.0|
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Heart                                   | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Infiltration Cellular, Focal,        |                                                                          |            |
          Mononuclear Cell                 |       1                                                                  |      1  1.0|
      Inflammation, Chronic, Focal         |                                                                          |      1  2.0|
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +  +  +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   | +  +  +  +  +  +  +  +  +  +                                             |  49        |
      Cytoplasmic Alteration, Focal        |                                                                          |      1  2.0|
      Hyperplasia, Focal                   |       1                                                                  |      1  1.0|
      Hypertrophy, Focal                   |    2                 2  1                                                |      8  1.8|
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  | +  +  +  +  +  +  +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +                                             |  47        |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | +  +  M  +  M  +  +  +  +  +                                             |  31        |
      Cyst                                 |                                                                          |      1     |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Pars Distalis, Cyst                  | X                                                                        |      3     |
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Depletion Secretory                  |                                                                          |      1     |
      Hemorrhage, Acute, Focal             |                                                                          |      1  2.0|
      Inflammation, Subacute               |                                                                          |      1  3.0|
      C-Cell, Hyperplasia, Chronic, Focal  |          1                                                               |      1  1.0|
      Follicular Cell, Hyperplasia         |                            3                                             |      1  3.0|
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Epididymis                              | +  +  +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Penis                                   |                                                                          |   1        |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  66                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 0| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 1| 3| 3| 3| 3|                                            |            |
                                           | 5| 0| 4| 0| 5| 5| 3| 0| 5| 5|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      A     |
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|                                            |      L     |
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 GENITAL SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
      Congestion                           |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Preputial Gland                         | +                                                                        |   2        |
      Abscess                              |                                                                          |      1  4.0|
      Inflammation, Chronic                | 4                                                                        |      1  4.0|
                                            __________________________________________________________________________|____________|
   Prostate                                | +  +  +  +  +  +  +  +  +  +                                             |  48        |
      Dilatation                           |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Seminal Vesicle                         |                                                                          |   2        |
      Dilatation                           |                                                                          |      2  4.0|
      Inflammation, Chronic, Diffuse       |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Testes                                  | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Atrophy, Diffuse                     |                                                                          |      1  4.0|
      Degeneration, Diffuse                |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Lymph Node                              | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Hematopoietic Cell Proliferation,    |                                                                          |            |
           Diffuse                         |                                                                          |      1  3.0|
      Thrombosis                           |                                                                          |      1     |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Ectasia, Diffuse                     |    3                    2                                                |      3  2.3|
      Giant Cell, Diffuse                  |                                                                          |      2  3.0|
      Hyperplasia, Diffuse, Re Cell        |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Hematopoietic Cell Proliferation,    |                                                                          |            |
           Diffuse                         |                                                                          |      4  3.8|
      Hyperplasia, Lymphoid                |                         4                                                |      4  3.3|
                                            __________________________________________________________________________|____________|
   Thymus                                  | +  +  M  +  +  +  +  +  I  +                                             |  35        |
      Atrophy, Diffuse                     | 3                                                                        |      2  3.5|
      Cyst                                 |                                                                          |      1     |
      Mediastinum, Inflammation, Acute     |                                                                          |      1  3.0|
      Medulla, Hyperplasia, Focal, Lymphoid|                                                                          |      1  3.0|
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           | M  M  M  M  M  M  M  M  M  M                                             |   1        |
                                            __________________________________________________________________________|____________|
   Skin                                    | +  +  +  +  +  +  +  +  +  +                                             |  49        |
      Edema, Acute, Diffuse                |                                                                          |      1  4.0|
      Inflammation, Chronic                |             4                                                            |      4  2.8|
      Inflammation, Subacute               |                                                                          |      1  2.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  67                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 0| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 1| 3| 3| 3| 3|                                            |            |
                                           | 5| 0| 4| 0| 5| 5| 3| 0| 5| 5|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      A     |
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|                                            |      L     |
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 INTEGUMENTARY SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Cartilage, Proliferation, Chronic,   |                                                                          |            |
           Focal                           |                                                                          |      1  3.0|
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Hydrocephalus                        |                                                                          |      1  2.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |                                                                          |      1  2.0|
      Mineralization, Multifocal           |    1  1  2  1        2  1                                                |     24  1.5|
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Congestion, Diffuse                  |                4                                                         |      5  3.4|
      Hemorrhage, Focal                    |                                                                          |      1  1.0|
      Hemorrhage, Multifocal               |                                                                          |      1  2.0|
      Hyperplasia, Focal, Adenomatous      |                                                                          |      1  1.0|
      Infiltration Cellular, Diffuse,      |                                                                          |            |
          Histiocyte                       |          3                                                               |      1  3.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 | 2  1        2     1  2     1                                             |     26  1.5|
      Infiltration Cellular, Multifocal,   |                                                                          |            |
           Histiocyte                      |                                                                          |      1  2.0|
      Inflammation, Chronic                |                                                                          |      1  1.0|
      Pleura, Inflammation, Subacute       |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Nose                                    | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Foreign Body                         |                                                                          |      1  1.0|
      Hyperplasia, Focal, Glandular        |                                                                          |      1  2.0|
      Inflammation, Acute                  |                   1                                                      |      3  1.7|
                                            __________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +  +  +  +  +  +  +                                             |  50        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Cyst                                 |                            X                                             |      5     |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  68                                                               
NTP Experiment-Test: 05704-01                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:24:54  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 0| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 1| 3| 3| 3| 3|                                            |            |
                                           | 5| 0| 4| 0| 5| 5| 3| 0| 5| 5|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      A     |
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|                                            |      L     |
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 URINARY SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
      Ectopic Tissue                       |                                                                          |      1     |
      Hyperplasia, Focal, Tubular          |                                                                          |      1  1.0|
      Hyperplasia, Multifocal, Tubular     |                                                                          |      1  3.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 | 2  1  1  2  1     1  3  2  2                                             |     36  1.4|
      Inflammation, Chronic                |                                                                          |      1  4.0|
      Nephropathy, Diffuse                 |                                                                          |      3  3.0|
      Vacuolization Cytoplasmic, Multifocal|                                                                          |      1  1.0|
      Cortex, Degeneration, Diffuse,       |                                                                          |            |
          Hyaline                          |                                                                          |      1  3.0|
      Cortex, Vacuolization Cytoplasmic,   |                                                                          |            |
           Multifocal                      |                                                                          |      1  2.0|
      Glomerulus, Amyloid Deposition,      |                                                                          |            |
          Diffuse                          |                                                                          |      1  2.0|
      Proximal Convoluted Renal Tubule,    |                                                                          |            |
           Degeneration, Focal             |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  +                                             |  48        |
      Concretion                           |                                                                          |      2  2.0|
      Edema, Acute, Diffuse                |                                                                          |      1  4.0|
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |                         2                                                |      1  2.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  69                                                               
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