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TDMS Study 55312-04 Pathology Tables

NTP                                         SUMMARY OF PAPILLOMAS AND CARCINOMAS *                                REPORT: EISRPT35  
LAB: Battelle Columbus                    COCONUT OIL ACID DIETHANOLAMINE CONDENSATE                              DATE: 09/18/97    
EXPERIMENT: 55312 TEST: 04                                                                                        TIME: 08:12:24    
                                                CAGES FROM 0000 TO LAST CAGE                                      PAGE:    1        
TEST TYPE: CHRONIC                                  ROUTE: SKIN APPLICATION                                       NTP:  C55312B     
CONT: N01-ES-15314                                                                                                CAS: 68603-42-9   

----------------------------------------------------------------------------------------------------------------------------------  

         SPECIES: MICE            STRAIN: B6C3F1        SEX: MALE      START-DATE: 01/20/93  WEEKS ON DOSE:   244                   
                                                                      ENDING DATE: 09/18/97                                         
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                                                                      DOSE LEVEL                                                    
----------------------------------------------------------------------------------------------------------------------------------  

                                    .000000    5.000000   10.000000                                                                 
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 SURVIVAL (1)                       0/50        0/50        0/50                                                                    

 PAPILLOMAS                                                                                                                         

   NUMBER / NUMBER SURVIVING (2)    0/0         0/0         0/0                                                                     

   PERCENT (3)                      0.00 %      0.00 %      0.00 %                                                                  

   MEAN (4)                         0.00        0.00        0.00                                                                    

   MEAN TUMOR BEARING ANIMALS (5)   0.00        0.00        0.00                                                                    

   TOTAL LESIONS PER GROUP (6)         0           0           0                                                                    

   WEEK OF ONSET (7)                   0           0           0                                                                    

 CARCINOMAS                                                                                                                         

   NUMBER / NUMBER SURVIVING (2)    0/0         0/0         0/0                                                                     

   PERCENT (3)                      0.00 %      0.00 %      0.00 %                                                                  

   MEAN (4)                         0.00        0.00        0.00                                                                    

   MEAN TUMOR BEARING ANIMALS (5)   0.00        0.00        0.00                                                                    

   TOTAL LESIONS PER GROUP (6)         0           0           0                                                                    

   WEEK OF ONSET (7)                   0           0           0                                                                    

                                                                                                                                    
 (1) NUMBER OF ANIMALS SURVIVING / NUMBER OF ANIMALS ALLOCATED                                                                      
 (2) NUMBER OF ANIMALS WITH LESIONS / NUMBER OF ANIMALS SURVIVING                                                                   
 (3) PERCENT OF SURVIVING ANIMALS WITH LESIONS                                                                                      
 (4) MEAN NUMBER OF LESIONS FOR ALL SURVIVING ANIMALS                                                                               
 (5) MEAN NUMBER OF LESIONS FOR SURVIVING ANIMALS WITH LESIONS                                                                      
 (6) TOTAL LESIONS FOR SURVIVING ANIMALS PER GROUP                                                                                  
 (7) THE WEEK THE FIRST ANIMAL WAS OBSERVED WITH LESIONS                                                                            

 *   HAS NOT BEEN CONFIRMED HISTOLOGICALLY                                                                                          
 #   INCLUDES ONE OR MORE ANIMALS HAVING 20 OR MORE LESIONS; COUNTED AS 20 IN CALCULATIONS                                          
NTP                                         SUMMARY OF PAPILLOMAS AND CARCINOMAS *                                REPORT: EISRPT35  
LAB: Battelle Columbus                    COCONUT OIL ACID DIETHANOLAMINE CONDENSATE                              DATE: 09/18/97    
EXPERIMENT: 55312 TEST: 04                                                                                        TIME: 08:12:24    
                                                CAGES FROM 0000 TO LAST CAGE                                      PAGE:    2        
TEST TYPE: CHRONIC                                  ROUTE: SKIN APPLICATION                                       NTP:  C55312B     
CONT: N01-ES-15314                                                                                                CAS: 68603-42-9   

----------------------------------------------------------------------------------------------------------------------------------  

         SPECIES: MICE            STRAIN: B6C3F1        SEX: MALE      START-DATE: 01/20/93  WEEKS ON DOSE:   244                   
                                                                      ENDING DATE: 09/18/97                                         
----------------------------------------------------------------------------------------------------------------------------------  

                                                                      DOSE LEVEL                                                    
----------------------------------------------------------------------------------------------------------------------------------  

                                    .000000    5.000000   10.000000                                                                 
----------------------------------------------------------------------------------------------------------------------------------  

 SURVIVAL (1)                       0/50        0/50        0/50                                                                    

 PAPILLOMAS AND CARCINOMAS COMBINED                                                                                                 

   NUMBER / NUMBER SURVIVING (2)    0/0000      0/0000      0/0000                                                                  

   PERCENT (3)                      0.00 %      0.00 %      0.00 %                                                                  

   MEAN (4)                         0.00        0.00        0.00                                                                    

   MEAN TUMOR BEARING ANIMALS (5)   0.00        0.00        0.00                                                                    

   TOTAL LESIONS PER GROUP (6)         0           0           0                                                                    

   WEEK OF ONSET (7)                   0           0           0                                                                    

                                                                                                                                    
 (1) NUMBER OF ANIMALS SURVIVING / NUMBER OF ANIMALS ALLOCATED                                                                      
 (2) NUMBER OF ANIMALS WITH LESIONS / NUMBER OF ANIMALS SURVIVING                                                                   
 (3) PERCENT OF SURVIVING ANIMALS WITH LESIONS                                                                                      
 (4) MEAN NUMBER OF LESIONS FOR ALL SURVIVING ANIMALS                                                                               
 (5) MEAN NUMBER OF LESIONS FOR SURVIVING ANIMALS WITH LESIONS                                                                      
 (6) TOTAL LESIONS FOR SURVIVING ANIMALS PER GROUP                                                                                  
 (7) THE WEEK THE FIRST ANIMAL WAS OBSERVED WITH LESIONS                                                                            

 *   HAS NOT BEEN CONFIRMED HISTOLOGICALLY                                                                                          
 #   INCLUDES ONE OR MORE ANIMALS HAVING 20 OR MORE LESIONS; COUNTED AS 20 IN CALCULATIONS                                          
NTP                                         SUMMARY OF PAPILLOMAS AND CARCINOMAS *                                REPORT: EISRPT35  
LAB: Battelle Columbus                    COCONUT OIL ACID DIETHANOLAMINE CONDENSATE                              DATE: 09/18/97    
EXPERIMENT: 55312 TEST: 04                                                                                        TIME: 08:12:24    
                                                CAGES FROM 0000 TO LAST CAGE                                      PAGE:    3        
TEST TYPE: CHRONIC                                  ROUTE: SKIN APPLICATION                                       NTP:  C55312B     
CONT: N01-ES-15314                                                                                                CAS: 68603-42-9   

----------------------------------------------------------------------------------------------------------------------------------  

         SPECIES: MICE            STRAIN: B6C3F1        SEX: FEMALE    START-DATE: 01/21/93  WEEKS ON DOSE:   244                   
                                                                      ENDING DATE: 09/18/97                                         
----------------------------------------------------------------------------------------------------------------------------------  

                                                                      DOSE LEVEL                                                    
----------------------------------------------------------------------------------------------------------------------------------  

                                    .000000    5.000000   10.000000                                                                 
----------------------------------------------------------------------------------------------------------------------------------  

 SURVIVAL (1)                       0/50        0/50        0/50                                                                    

 PAPILLOMAS                                                                                                                         

   NUMBER / NUMBER SURVIVING (2)    0/0         0/0         0/0                                                                     

   PERCENT (3)                      0.00 %      0.00 %      0.00 %                                                                  

   MEAN (4)                         0.00        0.00        0.00                                                                    

   MEAN TUMOR BEARING ANIMALS (5)   0.00        0.00        0.00                                                                    

   TOTAL LESIONS PER GROUP (6)         0           0           0                                                                    

   WEEK OF ONSET (7)                   0           0           0                                                                    

 CARCINOMAS                                                                                                                         

   NUMBER / NUMBER SURVIVING (2)    0/0         0/0         0/0                                                                     

   PERCENT (3)                      0.00 %      0.00 %      0.00 %                                                                  

   MEAN (4)                         0.00        0.00        0.00                                                                    

   MEAN TUMOR BEARING ANIMALS (5)   0.00        0.00        0.00                                                                    

   TOTAL LESIONS PER GROUP (6)         0           0           0                                                                    

   WEEK OF ONSET (7)                   0           0           0                                                                    

                                                                                                                                    
 (1) NUMBER OF ANIMALS SURVIVING / NUMBER OF ANIMALS ALLOCATED                                                                      
 (2) NUMBER OF ANIMALS WITH LESIONS / NUMBER OF ANIMALS SURVIVING                                                                   
 (3) PERCENT OF SURVIVING ANIMALS WITH LESIONS                                                                                      
 (4) MEAN NUMBER OF LESIONS FOR ALL SURVIVING ANIMALS                                                                               
 (5) MEAN NUMBER OF LESIONS FOR SURVIVING ANIMALS WITH LESIONS                                                                      
 (6) TOTAL LESIONS FOR SURVIVING ANIMALS PER GROUP                                                                                  
 (7) THE WEEK THE FIRST ANIMAL WAS OBSERVED WITH LESIONS                                                                            

 *   HAS NOT BEEN CONFIRMED HISTOLOGICALLY                                                                                          
 #   INCLUDES ONE OR MORE ANIMALS HAVING 20 OR MORE LESIONS; COUNTED AS 20 IN CALCULATIONS                                          
NTP                                         SUMMARY OF PAPILLOMAS AND CARCINOMAS *                                REPORT: EISRPT35  
LAB: Battelle Columbus                    COCONUT OIL ACID DIETHANOLAMINE CONDENSATE                              DATE: 09/18/97    
EXPERIMENT: 55312 TEST: 04                                                                                        TIME: 08:12:24    
                                                CAGES FROM 0000 TO LAST CAGE                                      PAGE:    4        
TEST TYPE: CHRONIC                                  ROUTE: SKIN APPLICATION                                       NTP:  C55312B     
CONT: N01-ES-15314                                                                                                CAS: 68603-42-9   

----------------------------------------------------------------------------------------------------------------------------------  

         SPECIES: MICE            STRAIN: B6C3F1        SEX: FEMALE    START-DATE: 01/21/93  WEEKS ON DOSE:   244                   
                                                                      ENDING DATE: 09/18/97                                         
----------------------------------------------------------------------------------------------------------------------------------  

                                                                      DOSE LEVEL                                                    
----------------------------------------------------------------------------------------------------------------------------------  

                                    .000000    5.000000   10.000000                                                                 
----------------------------------------------------------------------------------------------------------------------------------  

 SURVIVAL (1)                       0/50        0/50        0/50                                                                    

 PAPILLOMAS AND CARCINOMAS COMBINED                                                                                                 

   NUMBER / NUMBER SURVIVING (2)    0/0000      0/0000      0/0000                                                                  

   PERCENT (3)                      0.00 %      0.00 %      0.00 %                                                                  

   MEAN (4)                         0.00        0.00        0.00                                                                    

   MEAN TUMOR BEARING ANIMALS (5)   0.00        0.00        0.00                                                                    

   TOTAL LESIONS PER GROUP (6)         0           0           0                                                                    

   WEEK OF ONSET (7)                   0           0           0                                                                    

                                                                                                                                    
 (1) NUMBER OF ANIMALS SURVIVING / NUMBER OF ANIMALS ALLOCATED                                                                      
 (2) NUMBER OF ANIMALS WITH LESIONS / NUMBER OF ANIMALS SURVIVING                                                                   
 (3) PERCENT OF SURVIVING ANIMALS WITH LESIONS                                                                                      
 (4) MEAN NUMBER OF LESIONS FOR ALL SURVIVING ANIMALS                                                                               
 (5) MEAN NUMBER OF LESIONS FOR SURVIVING ANIMALS WITH LESIONS                                                                      
 (6) TOTAL LESIONS FOR SURVIVING ANIMALS PER GROUP                                                                                  
 (7) THE WEEK THE FIRST ANIMAL WAS OBSERVED WITH LESIONS                                                                            

 *   HAS NOT BEEN CONFIRMED HISTOLOGICALLY                                                                                          
 #   INCLUDES ONE OR MORE ANIMALS HAVING 20 OR MORE LESIONS; COUNTED AS 20 IN CALCULATIONS                                          
NTP                                         SUMMARY OF PAPILLOMAS AND CARCINOMAS *                                REPORT: EISRPT35  
LAB: Battelle Columbus                    COCONUT OIL ACID DIETHANOLAMINE CONDENSATE                              DATE: 09/18/97    
EXPERIMENT: 55312 TEST: 04                                                                                        TIME: 08:12:24    
                                                CAGES FROM 0000 TO LAST CAGE                                      PAGE:    5        
TEST TYPE: CHRONIC                                  ROUTE: SKIN APPLICATION                                       NTP:  C55312B     
CONT: N01-ES-15314                                                                                                CAS: 68603-42-9   

----------------------------------------------------------------------------------------------------------------------------------  

         SPECIES: MICE            STRAIN: B6C3F1        SEX: FEMALE    START-DATE: 01/21/93  WEEKS ON DOSE:   244                   
                                                                      ENDING DATE: 09/18/97                                         
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