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TDMS Study 56348-04 Pathology Tables

NTP Experiment-Test: 56348-04                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                               CITRAL                                          Date: 07/05/01
Route: DOSED FEED                                                                                                 Time: 13:38:50




       Facility:  Battelle Columbus Laboratory

       Chemical CAS #:  5392-40-5

       Lock Date:  03/25/99

       Cage Range:  All

       Reasons For Removal:    All

       Removal Date Range:     All

       Treatment Groups:       Include All






































                                                              Page   1


NTP Experiment-Test: 56348-04                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09  
Study Type: CHRONIC                                               CITRAL                                          Date: 07/05/01    
Route: DOSED FEED                                                                                                 Time: 13:38:50    
 _____________________________________________________________________________________________________________________              
                                           | 7| 2| 2| 2| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 7| 5| 7| 5| 7| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 4| 4| 4| 3| 0| 3| 3| 3| 3| 3| 3| 3| 5| 3| 3| 4| 3| 4| 3| 3| 3| 3| 3| 3|             
                                           | 4| 3| 2| 2| 3| 9| 4| 5| 5| 3| 5| 3| 3| 7| 4| 4| 5| 4| 4| 5| 4| 4| 5| 4| 3|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    UNTREAT                                | 5| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7|             
    CONTROL                                | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |__________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Gallbladder                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Ectasia                              |                3                                                         |             
      Inflammation, Chronic                |                                                                          |             
      Epithelium, Hyperplasia, Focal       |                                                                      1   |             
      Epithelium, Metaplasia, Squamous     |                                                                      1   |             
                                           |__________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Peyer's Patch, Hyperplasia, Lymphoid |                                                                          |             
                                           |__________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Inflammation, Chronic                |                                                                          |             
      Inflammation, Granulomatous          |                                                                          |             
      Ulcer                                |                                                                          |             
                                           |__________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Clear Cell Focus                     |                                     X                                    |             
      Hematopoietic Cell Proliferation     |                2                                                         |             
      Infiltration Cellular, Lymphocyte    |                   1  1  1  1     1  1     1                 1        1   |             
      Inflammation, Granulomatous          | 1        1  1  1     1  1        1           1     1     1  1     1      |             
      Mixed Cell Focus                     |                                                             X            |             
      Necrosis, Focal                      |    2  2                                                                  |             
      Vacuolization Cytoplasmic, Focal     | 1        1                                                     1  1      |             
      Bile Duct, Inflammation,             |                                                                          |             
          Granulomatous                    |                                                                          |             
      Centrilobular, Degeneration          |                                                                          |             
                                           |__________________________________________________________________________|             
   Mesentery                               |                +              +        +     +                           |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                             Page   2                                                               
                                                                                                                                   
NTP Experiment-Test: 56348-04                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09  
Study Type: CHRONIC                                               CITRAL                                          Date: 07/05/01    
Route: DOSED FEED                                                                                                 Time: 13:38:50    
 _____________________________________________________________________________________________________________________              
                                           | 7| 2| 2| 2| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 7| 5| 7| 5| 7| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 4| 4| 4| 3| 0| 3| 3| 3| 3| 3| 3| 3| 5| 3| 3| 4| 3| 4| 3| 3| 3| 3| 3| 3|             
                                           | 4| 3| 2| 2| 3| 9| 4| 5| 5| 3| 5| 3| 3| 7| 4| 4| 5| 4| 4| 5| 4| 4| 5| 4| 3|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    UNTREAT                                | 5| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7|             
    CONTROL                                | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
      Infiltration Cellular, Mast Cell     |                                                                          |             
      Inflammation, Granulomatous          |                                              2                           |             
      Fat, Necrosis                        |                4              1        2                                 |             
                                           |__________________________________________________________________________|             
   Oral Mucosa                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Infiltration Cellular, Mast Cell     |                                                                          |             
      Inflammation, Chronic Active         | 2                 1              2     1        2  2     1     1  2      |             
      Ulcer                                | 2                                               1                 1      |             
                                           |__________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Infiltration Cellular, Mast