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TDMS Study 88120-03 Pathology Tables

NTP                             FEED, WATER, AND COMPOUND CONSUMPTION TABLE                                       REPORT: EISRPT39  
LAB: Battelle Columbus                           P,P'-DICHLORODIPHENYL SULFONE                                    DATE: 10/27/99    
EXPERIMENT: 88120 TEST: 03                                                                                        TIME: 12:42:10    
                                                CAGES FROM 0000 TO LAST CAGE                                      PAGE:    1        
TEST TYPE: CHRONIC                                  ROUTE: DOSED FEED                                             NTP:  C88120B     
CONT: NO1-ES-55388                                                                                                CAS: 80-07-9      
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               REASONS FOR REMOVAL:    ALL                                                                                          
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
               REMOVAL DATE RANGE:     ALL                                                                                          
                                                                                                                                    
               TREATMENT GROUPS:       INCLUDE ALL                                                                                  




NTP                                         FEED, WATER, AND COMPOUND CONSUMPTION TABLE                           REPORT: EISRPT39

LAB: BATTELLE COLUMBUS LABORATORY                     P,P'-DICHLORODIPHENYL SULFONE                               DATE: 10/27/99


EXPERIMENT: 88120 TEST: 03                                                                                        TIME: 12:59:29



TEST TYPE: CHRONIC                                  ROUTE: DOSED FEED                                             NTP:  88120B

CONT: NO1-ES-55388                                                                                                CAS: 80-07-9
                                          FEED AND COMPOUND CONSUMPTION BY MALE RATS IN THE
                                       CHRONIC DOSED FEED STUDY OF P,P'-DICHLORODIPHENYL SULFONE

==================================================================================================================================
           0 PPM                       10 PPM                             30 PPM                            100 PPM
     ----------------    ---------------------------------  ---------------------------------  ---------------------------------
                                          DOSE/                              DOSE/                              DOSE/
      GRAMS    BODY      GRAMS    BODY    CONTROL           GRAMS    BODY    CONTROL           GRAMS    BODY    CONTROL
      FEED/   WEIGHT     FEED/   WEIGHT  FEED (B)    DOSE/  FEED/   WEIGHT  FEED (B)    DOSE/  FEED/   WEIGHT  FEED (B)    DOSE/
WEEK  DAY(A)  (GRAMS)    DAY(A)  (GRAMS)  (GRAMS)   DAY(C)  DAY(A)  (GRAMS)  (GRAMS)   DAY(C)  DAY(A)  (GRAMS)  (GRAMS)   DAY(C)
==================================================================================================================================
  1    18.2   103.3      17.8    102.5    0.98      1.7     16.7    101.9    0.92      4.9     17.7    102.7    0.97     17.2
  2    18.0   151.5      18.3    148.1    1.02      1.2     17.3    147.4    0.96      3.5     17.3    150.2    0.96     11.5
  6    19.0   267.6      19.0    256.8    1.00      0.7     18.8    256.1    0.99      2.2     19.6    260.2    1.03      7.5
 10    18.6   325.1      18.6    318.0    1.00      0.6     18.3    313.0    0.98      1.8     18.7    315.6    1.01      5.9
 14    17.6   365.2      17.9    357.1    1.02      0.5     18.0    353.8    1.02      1.5     18.7    353.7    1.06      5.3
 18    19.5   396.8      18.4    385.3    0.94      0.5     18.9    382.9    0.97      1.5     19.5    387.2    1.00      5.0
 22    18.3   414.3      18.7    407.3    1.02      0.5     18.0    399.5    0.98      1.4     18.1    398.0    0.99      4.5
 26    18.9   431.5      18.6    423.8    0.98      0.4     18.8    415.1    0.99      1.4     19.0    411.7    1.01      4.6
 30    19.0   442.8      18.5    432.5    0.97      0.4     19.8    426.8    1.04      1.4     19.2    427.0    1.01      4.5
 34    20.2   451.9      19.8    444.8    0.98      0.4     19.8    438.6    0.98      1.4     20.3    433.0    1.00      4.7
 38    18.7   457.7      18.7    451.4    1.00      0.4     18.3    441.8    0.98      1.2     19.7    439.9    1.05      4.5
 42    18.4   468.1      18.8    460.0    1.02      0.4     19.1    451.5    1.04      1.3     19.2    454.7    1.04      4.2
 46    18.3   473.6      18.5    466.0    1.01      0.4     19.0    454.3    1.04      1.3     18.8    452.8    1.03      4.2
 50    20.0   476.4      20.6    468.7    1.03      0.4     21.4    460.9    1.07      1.4     21.3    458.0    1.07      4.6
 54    18.4   482.2      17.1    472.8    0.93      0.4     18.2    465.7    0.99      1.2     19.1    461.0    1.04      4.1
 58    18.8   482.4      18.1    473.7    0.96      0.4     18.2    464.4    0.97      1.2     18.4    458.5    0.98      4.0
 62    19.0   482.7      19.0    475.5    1.00      0.4     18.9    467.1    0.99      1.2     19.0    460.6    1.00      4.1
 66    18.5   486.9      17.9    473.1    0.97      0.4     18.7    464.9    1.01      1.2     18.4    455.1    0.99      4.0
 70    20.1   487.6      19.9    477.2    0.99      0.4     19.3    469.2    0.96      1.2     19.8    456.4    0.99      4.3
 74    18.0   492.4      18.3    472.5    1.02      0.4     17.8    466.6    0.99      1.1     18.0    458.6    1.00      3.9
 78    18.8   496.8      18.6    483.2    0.99      0.4     17.9    471.2    0.95      1.1     17.4    460.5    0.93      3.8
 82    17.8   485.6      16.7    478.2    0.94      0.4     17.1    468.4    0.96      1.1     17.4    461.2    0.98      3.8
 86    17.3   485.4      17.5    475.1    1.01      0.4     17.6    459.1    1.02      1.2     17.1    452.3    0.99      3.8
 89    18.1   482.0      17.2    471.1    0.95      0.4     18.3    458.4    1.01      1.2     18.2    447.5    1.01      4.1
 94    18.6   476.0      17.8    462.2    0.96      0.4     17.5    446.3    0.94      1.2     17.6    441.8    0.95      4.0
 98    18.2   461.5      18.0    462.4    0.99      0.4     18.9    444.0    1.04      1.3     18.6    440.4    1.02      4.2
102    17.9   464.8      17.8    450.7    0.99      0.4     18.5    425.1    1.03      1.3     17.3    434.2    0.97      4.0

1 TO 13 WEEKS 
----------------
MEAN   18.4   211.9      18.4    206.3    1.00      1.1     17.8    204.6    0.96      3.1     18.3    207.2    0.99     10.5
SD(D)   0.5               0.5             0.02      0.5      0.9             0.03      1.4      1.1             0.03      5.0
CV(E)   2.5               2.9             1.6      48.5      5.2             3.4      46.1      5.8             3.2      47.6

14 TO 52 WEEKS
----------------
MEAN   18.9   437.8      18.8    429.7    1.00      0.4     19.1    422.5    1.01      1.4     19.4    421.6    1.03      4.6
SD(D)   0.8               0.8             0.03      0.0      1.0             0.03      0.1      0.9             0.03      0.3
CV(E)   4.3               4.2             2.7       7.2      5.3             3.4       6.9      4.6             2.7       7.4

> 52 WEEKS    
----------------
MEAN   18.4   482.0      18.0    471.4    0.98      0.4     18.2    459.3    0.99      1.2     18.2    452.9    0.99      4.0
SD(D)   0.7               0.8             0.03      0.0      0.6             0.03      0.1      0.8             0.03      0.2
CV(E)   3.8               4.7             2.8       4.6      3.5             3.2       4.8      4.5             3.0       4.3
==================================================================================================================================

(A) GRAMS OF FEED CONSUMED PER ANIMAL PER DAY.
(B) GRAMS OF FEED PER DAY FOR THE DOSED GROUP DIVIDED BY THAT FOR THE CONTROLS.
(C) MILLIGRAMS OF COMPOUND CONSUMED PER DAY PER KILOGRAM BODY WEIGHT.
(D) STANDARD DEVIATION OF WEEKLY MEAN.
(E) COEFFICIENT OF VARIATION = (STANDARD DEVIATION / MEAN) X 100.
                                          FEED AND COMPOUND CONSUMPTION BY FEMALE RATS IN THE
                                       CHRONIC DOSED FEED STUDY OF P,P'-DICHLORODIPHENYL SULFONE

==================================================================================================================================
           0 PPM                       30 PPM                            100 PPM                            300 PPM
     ----------------    ---------------------------------  ---------------------------------  ---------------------------------
                                           DOSE/                              DOSE/                              DOSE/
      GRAMS    BODY      GRAMS    BODY    CONTROL           GRAMS    BODY    CONTROL           GRAMS    BODY    CONTROL
      FEED/   WEIGHT     FEED/   WEIGHT  FEED (B)    DOSE/  FEED/   WEIGHT  FEED (B)    DOSE/  FEED/   WEIGHT  FEED (B)    DOSE/
WEEK  DAY(A)  (GRAMS)    DAY(A)  (GRAMS)  (GRAMS)   DAY(C)  DAY(A)  (GRAMS)  (GRAMS)   DAY(C)  DAY(A)  (GRAMS)  (GRAMS)   DAY(C)
==================================================================================================================================
  1    13.0    92.8      13.0     92.7     1.00     4.2     13.0     94.0     1.00    13.8     12.8     93.2     0.98    41.2
  2    12.4   119.3      12.3    118.3     0.99     3.1     11.7    117.7     0.94    10.0     12.0    118.4     0.97    30.4
  6    12.7   168.6      12.2    163.5     0.96     2.2     12.2    164.5     0.96     7.4     12.0    160.2     0.94    22.5
 10    11.2   189.2      11.1    183.9     0.99     1.8     11.7    185.6     1.04     6.3     11.3    179.2     1.01    18.9
 14    10.8   198.9      10.3    194.4     0.95     1.6     10.8    195.7     1.00     5.5     10.3    187.9     0.95    16.4
 18    11.4   211.1      10.5    203.8     0.92     1.5     10.7    205.3     0.94     5.2     10.5    196.6     0.92    16.0
 22    11.3   219.0      10.6    210.7     0.94     1.5     10.8    211.0     0.96     5.1     10.7    203.2     0.95    15.7
 26    11.0   222.3      10.9    217.2     0.99     1.5     11.1    215.6     1.01     5.1     11.0    207.2     1.00    15.9
 30    11.3   232.2      11.1    222.9     0.98     1.5     11.0    221.5     0.97     5.0     10.7    209.6     0.95    15.4
 34    12.7   235.5      12.3    227.5     0.97     1.6     12.7    222.2     1.00     5.7     12.2    213.1     0.96    17.1
 38    12.5   242.3      11.6    233.2     0.93     1.5     12.5    228.3     1.00     5.5     11.7    218.4     0.94    16.1
 42    11.8   247.8      11.0    237.6     0.93     1.4     11.6    232.0     0.98     5.0     10.8    220.8     0.92    14.7
 46    12.5   256.5      11.8    243.7     0.94     1.5     11.9    238.6     0.95     5.0     11.5    225.9     0.92    15.3
 50    12.7   264.1      11.8    252.6     0.93     1.4     11.8    246.6     0.93     4.8     11.5    231.2     0.91    14.9
 54    12.8   270.9      12.2    259.0     0.95     1.4     12.0    252.2     0.94     4.8     12.1    236.3     0.95    15.3
 58    12.5   278.3      12.0    268.5     0.96     1.3     12.5    260.1     1.00     4.8     11.8    242.2     0.94    14.6
 62    12.8   287.4      12.9    279.0     1.01     1.4     13.3    270.3     1.04     4.9     12.3    251.6     0.96    14.6
 66    12.8   295.4      12.7    284.6     0.99     1.3     12.4    275.6     0.97     4.5     12.4    257.1     0.97    14.5
 70    13.1   300.4      13.2    293.0     1.01     1.4     12.7    281.3     0.97     4.5     12.7    261.6     0.97    14.5
 74    13.6   310.2      13.5    299.3     0.99     1.4     13.2    286.6     0.97     4.6     12.3    266.9     0.90    13.8
 78    13.1   320.7      12.8    310.0     0.98     1.2     12.6    298.8     0.96     4.2     12.6    278.9     0.96    13.5
 82    13.4   321.0      12.7    312.0     0.95     1.2     12.4    295.7     0.93     4.2     12.2    277.3     0.91    13.2
 86    13.2   321.0      12.1    311.7     0.92     1.2     12.2    298.4     0.92     4.1     12.3    281.4     0.93    13.2
 90    12.9   313.3      13.0    309.7     1.01     1.3     12.4    295.2     0.96     4.2     12.4    279.7     0.96    13.3
 94    14.0   321.1      13.1    310.3     0.94     1.3     12.9    300.4     0.92     4.3     13.7    285.7     0.98    14.4
 98    14.1   324.6      13.5    318.2     0.96     1.3     14.2    306.2     1.01     4.6     14.0    289.1     0.99    14.5
102    14.5   330.5      13.5    317.0     0.93     1.3     13.6    305.2     0.94     4.5     13.4    287.5     0.92    14.0

1 TO 13 WEEKS 
----------------
MEAN   12.4   142.5      12.1    139.6     0.99     2.8     12.2    140.4     0.99     9.4     12.0    137.7     0.98    28.2
SD(D)   0.8               0.8              0.02     1.1      0.6              0.04     3.3      0.6              0.03     9.9
CV(E)   6.4               6.6              1.8     37.4      4.9              4.6     35.6      5.1              2.8     35.0

14 TO 52 WEEKS
----------------
MEAN   11.8   233.0      11.2    224.3     0.95     1.5     11.5    221.7     0.97     5.2     11.1    211.4     0.94    15.8
SD(D)   0.7               0.7              0.02     0.1      0.7              0.03     0.3      0.6              0.03     0.7
CV(E)   6.2               6.1              2.6      4.9      6.4              2.9      5.6      5.4              2.9      4.6

> 52 WEEKS    
----------------
MEAN   13.3   307.3      12.9    297.9     0.97     1.3     12.8    286.6     0.96     4.5     12.6    268.9     0.95    14.1
SD(D)   0.6               0.5              0.03     0.1      0.6              0.04     0.3      0.7              0.03     0.7
CV(E)   4.6               4.0              3.2      5.5      4.8              3.7      5.8      5.3              2.8      4.8
==================================================================================================================================

(A) GRAMS OF FEED CONSUMED PER ANIMAL PER DAY.
(B) GRAMS OF FEED PER DAY FOR THE DOSED GROUP DIVIDED BY THAT FOR THE CONTROLS.
(C) MILLIGRAMS OF COMPOUND CONSUMED PER DAY PER KILOGRAM BODY WEIGHT.
(D) STANDARD DEVIATION OF WEEKLY MEAN.
(E) COEFFICIENT OF VARIATION = (STANDARD DEVIATION / MEAN) X 100.
                          DIAGNOSTIC TRAILER REPORT
                          FEED AND COMPOUND CONSUMPTION BY MALE RATS IN THE
                          CHRONIC DOSED FEED STUDY OF P,P'-DICHLORODIPHENYL SULFONE
=========================================================================================================
           0 PPM                    10 PPM                   30 PPM                  100 PPM
     ----------------------   ----------------------   ----------------------   ----------------------
     DAILY FEED  BODY  NUM    DAILY FEED  BODY  NUM    DAILY FEED  BODY  NUM    DAILY FEED  BODY  NUM
WEEK FEED HOURS   WGT  WGTS   FEED HOURS   WGT  WGTS   FEED HOURS   WGT  WGTS   FEED HOURS   WGT  WGTS
==========================================================================================================
  B              103.3  50                102.5  50                101.9  50                102.7  50
  1  18.2  3579  103.3  50    17.8  3590  102.5  50    16.7  3571  101.9  50    17.7  3617  102.7  50
  2  18.0  5043  151.5  50    18.3  4988  148.1  50    17.3  5012  147.4  50    17.3  5013  150.2  50
  5  19.6  3600               19.5  3612               19.1  3607               18.8  3610           
  6  19.0  4806  267.6  50    19.0  4817  256.8  50    18.8  4831  256.1  50    19.6  4816  260.2  50
  9  18.0  3606               18.4  3616               18.3  3617               19.0  3617           
 10  18.6  4816  325.1  50    18.6  4823  318.0  50    18.3  4841  313.0  50    18.7  4834  315.6  50
 13  18.6  3561               20.1  3528               19.7  3563               19.4  3600           
 14  17.6  4950  365.2  50    17.9  4687  357.1  50    18.0  5033  353.8  50    18.7  4951  353.7  50
 17  19.4  3513               18.8  3524               18.1  3533               19.2  3550           
 18  19.5  4812  396.8  50    18.4  4883  385.3  50    18.9  4830  382.9  50    19.5  4799  387.2  50
 21  19.4  3250               20.1  3065               19.5  3274               19.7  3102           
 22  18.3  4819  414.3  50    18.7  4833  407.3  50    18.0  4845  399.5  50    18.1  4891  398.0  50
 25  19.1  3550               19.0  3546               19.5  3513               19.3  3518           
 26  18.9  4817  431.5  50    18.6  4827  423.8  50    18.8  4879  415.1  50    19.0  4583  411.7  50
 29  19.3  3623               19.1  3445               19.5  3644               19.6  3394           
 30  19.0  4723  442.8  50    18.5  4498  432.5  50    19.8  4715  426.8  50    19.2  4397  427.0  50
 33  20.9  3637               20.4  3599               20.0  3652               19.9  3790           
 34  20.2  4791  451.9  50    19.8  4783  444.8  50    19.8  4756  438.6  50    20.3  4719  433.0  50
 37  20.7  3353               21.3  3577               21.1  3368               20.9  3596           
 38  18.7  5000  457.7  50    18.7  5006  451.4  50    18.3  5050  441.8  50    19.7  5039  439.9  50
 41  19.4  3584               18.8  3579               19.8  3617               20.1  3601           
 42  18.4  4751  468.1  50    18.8  4818  460.0  50    19.1  4798  451.5  50    19.2  4761  454.7  50
 45  19.2  3554               19.8  3543               18.1  3544               19.3  3533           
 46  18.3  4632  473.6  48    18.5  4822  466.0  50    19.0  4835  454.3  50    18.8  4849  452.8  50
 49  19.6  3488               20.0  3640               20.8  3650               20.8  3650           
 50  20.0  4234  476.4  48    20.6  4514  468.7  50    21.4  4475  460.9  50    21.3  4135  458.0  50
 53  18.1  3248               18.3  3549               18.6  3543               19.1  3632           
 54  18.4  4334  482.2  46    17.1  4694  472.8  50    18.2  4702  465.7  50    19.1  4641  461.0  50
 57  18.5  3354               18.8  3120               19.2  3621               19.1  3617           
 58  18.8  4435  482.4  46    18.1  4743  473.7  49    18.2  4908  464.4  49    18.4  4918  458.5  50
 61  17.9  3408               18.6  3546               18.8  3598               18.5  3667           
 62  19.0  4366  482.7  46    19.0  4652  475.5  48    18.9  4681  467.1  49    19.0  4726  460.6  50
 65  18.8  3312               18.6  3317               18.5  3465               18.6  3606           
 66  18.5  4300  486.9  45    17.9  4458  473.1  48    18.7  4692  464.9  48    18.4  4894  455.1  50
 69  19.1  3190               19.0  3563               18.3  3557               18.5  3700           
 70  20.1  4064  487.6  45    19.9  4358  477.2  48    19.3  4524  469.2  47    19.8  4783  456.4  50
 73  19.0  3276               17.4  3380               17.3  3404               17.7  3576           
 74  18.0  4269  492.4  44    18.3  4346  472.5  48    17.8  4394  466.6  46    18.0  4666  458.6  49
 77  17.6  3325               17.0  3541               15.9  3385               16.6  3608           
 78  18.8  4085  496.8  44    18.6  4374  483.2  47    17.9  4129  471.2  44    17.4  4456  460.5  47
 81  17.5  3224               16.3  3434               17.5  3015               17.5  3151           
 82  17.8  4069  485.6  44    16.7  4489  478.2  47    17.1  3908  468.4  41    17.4  3881  461.2  46
 85  18.3  3082               18.3  3159               17.5  2953               17.7  3103           
 86  17.3  4129  485.4  43    17.5  4230  475.1  44    17.6  3777  459.1  40    17.1  3971  452.3  42
 89  18.1  6410  482.0  38    17.2  7079  471.1  42    18.3  5923  458.4  37    18.2  6514  447.5  40
 93  18.4  2248               17.9  2894               18.0  2571               17.8  2646           
 94  18.6  3129  476.0  33    17.8  3761  462.2  41    17.5  3579  446.3  36    17.6  3583  441.8  37
 97  17.9  2162               16.7  2693               17.0  2384               18.0  2292           
 98  18.2  2965  461.5  32    18.0  3336  462.4  37    18.9  2945  444.0  32    18.6  3151  440.4  34
=========================================================================================================
                          DIAGNOSTIC TRAILER REPORT
                          FEED AND COMPOUND CONSUMPTION BY MALE RATS IN THE
                          CHRONIC DOSED FEED STUDY OF P,P'-DICHLORODIPHENYL SULFONE
=========================================================================================================
           0 PPM                    10 PPM                   30 PPM                  100 PPM
     ----------------------   ----------------------   ----------------------   ----------------------
     DAILY FEED  BODY  NUM    DAILY FEED  BODY  NUM    DAILY FEED  BODY  NUM    DAILY FEED  BODY  NUM
WEEK FEED HOURS  WGT   WGTS   FEED HOURS  WGT   WGTS   FEED HOURS  WGT   WGTS   FEED HOURS  WGT   WGTS
==========================================================================================================
101  18.8  1702               17.3  2081               17.8  1632               18.1  1919           
102  17.9  2591  464.8  28    17.8  2762  450.7  34    18.5  2004  425.1  28    17.3  2906  434.2  30

MEAN BODY WGT FOR WEEKS
1 TO 13          211.9                    206.3                    204.6                    207.2
14 TO 52         437.8                    429.7                    422.5                    421.6
 > 52            482.0                    471.4                    459.3                    452.9
=========================================================================================================

    (B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
                          DIAGNOSTIC TRAILER REPORT
                          FEED AND COMPOUND CONSUMPTION BY FEMALE RATS IN THE
                          CHRONIC DOSED FEED STUDY OF P,P'-DICHLORODIPHENYL SULFONE
=========================================================================================================
           0 PPM                    30 PPM                  100 PPM                  300 PPM
     ----------------------   ----------------------   ----------------------   ----------------------
     DAILY FEED  BODY  NUM    DAILY FEED  BODY  NUM    DAILY FEED  BODY  NUM    DAILY FEED  BODY  NUM
WEEK FEED HOURS   WGT  WGTS   FEED HOURS   WGT  WGTS   FEED HOURS   WGT  WGTS   FEED HOURS   WGT  WGTS
==========================================================================================================
  B               92.8  50                 92.7  50                 94.0  50                 93.2  50
  1  13.0  3585   92.8  50    13.0  3580   92.7  50    13.0  3585   94.0  50    12.8  3583   93.2  50
  2  12.4  4910  119.3  50    12.3  4912  118.3  50    11.7  4909  117.7  50    12.0  4896  118.4  50
  5  12.3  3645               12.2  3644               12.1  3645               11.9  3650           
  6  12.7  4800  168.6  50    12.2  4839  163.5  50    12.2  4799  164.5  50    12.0  4819  160.2  50
  9  10.9  3628               11.3  3640               11.4  3644               11.1  3697           
 10  11.2  4760  189.2  50    11.1  4779  183.9  50    11.7  4738  185.6  50    11.3  4712  179.2  50
 13  11.1  3577               12.0  3580               11.8  3580               11.4  3580           
 14  10.8  4938  198.9  50    10.3  5001  194.4  50    10.8  4945  195.7  50    10.3  5056  187.9  50
 17  11.7  3570               10.5  3585               11.2  3559               10.7  3570           
 18  11.4  4954  211.1  50    10.5  4874  203.8  50    10.7  4926  205.3  50    10.5  4881  196.6  50
 21  11.7  3425               11.5  3430               12.2  3435               11.3  3440           
 22  11.3  4830  219.0  50    10.6  4840  210.7  50    10.8  4848  211.0  50    10.7  4857  203.2  50
 25  11.1  3557               11.2  3563               10.9  3590               10.5  3595           
 26  11.0  4798  222.3  50    10.9  4799  217.2  50    11.1  4781  215.6  50    11.0  4792  207.2  50
 29  12.1  3563               11.4  3565               12.0  3560               11.4  3565           
 30  11.3  4795  232.2  50    11.1  4803  222.9  50    11.0  4812  221.5  50    10.7  4821  209.6  50
 33  12.4  3845               11.6  3845               10.7  3841               11.2  3841           
 34  12.7  4530  235.5  50    12.3  4564  227.5  50    12.7  4078  222.2  50    12.2  4560  213.1  50
 37  13.5  3590               13.1  3590               13.8  3600               13.1  3565           
 38  12.5  4818  242.3  50    11.6  4827  233.2  50    12.5  4827  228.3  50    11.7  4859  218.4  50
 41  12.6  3595               11.4  3600               11.4  3600               11.2  3600           
 42  11.8  4854  247.8  50    11.0  4846  237.6  50    11.6  4844  232.0  50    10.8  4825  220.8  50
 45  12.9  3624               11.3  3625               12.0  3617               12.6  3514           
 46  12.5  4754  256.5  50    11.8  4767  243.7  50    11.9  4785  238.6  50    11.5  4741  225.9  49
 49  13.8  3490               12.8  3490               12.9  3495               12.2  3427           
 50  12.7  4887  264.1  50    11.8  4901  252.6  50    11.8  4920  246.6  50    11.5  4869  231.2  49
 53  12.4  3475               12.4  3351               12.6  3352               11.9  3346           
 54  12.8  4776  270.9  50    12.2  4787  259.0  50    12.0  4796  252.2  50    12.1  4613  236.3  48
 57  14.0  3249               13.2  3610               13.8  3605               13.1  3462           
 58  12.5  4324  278.3  50    12.0  4818  268.5  50    12.5  4834  260.1  50    11.8  4672  242.2  48
 61  13.3  3514               12.8  3518               12.6  3590               12.6  3375           
 62  12.8  4700  287.4  49    12.9  4708  279.0  49    13.3  4814  270.3  50    12.3  4538  251.6  47
 65  12.6  3101               12.3  3438               12.4  3610               12.5  3394           
 66  12.8  4622  295.4  48    12.7  4531  284.6  47    12.4  4827  275.6  50    12.4  4545  257.1  47
 69  12.1  3658               12.5  3581               12.1  3729               12.1  3494           
 70  13.1  4439  300.4  48    13.2  4364  293.0  47    12.7  4562  281.3  49    12.7  4296  261.6  46
 73  12.9  3478               12.7  3474               12.7  3616               12.1  3390           
 74  13.6  4409  310.2  47    13.5  4423  299.3  47    13.2  4623  286.6  49    12.3  4336  266.9  45
 77  13.0  3374               12.8  3374               13.0  3427               12.7  3154           
 78  13.1  4499  320.7  47    12.8  4507  310.0  47    12.6  4517  298.8  47    12.6  4263  278.9  44
 81  13.0  3415               11.6  3421               11.8  3492               11.7  3271           
 82  13.4  4335  321.0  46    12.7  4344  312.0  46    12.4  4458  295.7  47    12.2  4214  277.3  44
 85  13.1  3261               12.7  3339               12.3  3044               11.7  3122           
 86  13.2  4228  321.0  45    12.1  4332  311.7  46    12.2  4343  298.4  46    12.3  4064  281.4  43
 89  14.0  3103               13.5  3172               13.4  3241               13.2  2958           
 90  12.9  4416  313.3  44    13.0  4528  309.7  45    12.4  4648  295.2  46    12.4  4253  279.7  42
 93  13.7  3112               12.2  3213               12.6  3300               13.3  2755           
 94  14.0  3584  321.1  42    13.1  4203  310.3  44    12.9  4335  300.4  45    13.7  3369  285.7  38
 97  13.9  2449               12.9  2890               13.7  3101               13.9  2664           
=========================================================================================================
                          DIAGNOSTIC TRAILER REPORT
                          FEED AND COMPOUND CONSUMPTION BY FEMALE RATS IN THE
                          CHRONIC DOSED FEED STUDY OF P,P'-DICHLORODIPHENYL SULFONE
=========================================================================================================
           0 PPM                    30 PPM                  100 PPM                  300 PPM
     ----------------------   ----------------------   ----------------------   ----------------------
     DAILY FEED  BODY  NUM    DAILY FEED  BODY  NUM    DAILY FEED  BODY  NUM    DAILY FEED  BODY  NUM
WEEK FEED HOURS  WGT   WGTS   FEED HOURS  WGT   WGTS   FEED HOURS  WGT   WGTS   FEED HOURS  WGT   WGTS
==========================================================================================================
 98  14.1  3412  324.6  39    13.5  3821  318.2  39    14.2  4032  306.2  42    14.0  3603  289.1  37
101  14.0  2754               13.0  2603               12.5  2977               12.7  2692           
102  14.5  3512  330.5  37    13.5  3088  317.0  38    13.6  3602  305.2  39    13.4  2920  287.5  35

MEAN BODY WGT FOR WEEKS
1 TO 13          142.5                    139.6                    140.4                    137.7
14 TO 52         233.0                    224.3                    221.7                    211.4
 > 52            307.3                    297.9                    286.6                    268.9
=========================================================================================================

    (B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.

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