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TDMS Study 88124-03 Pathology Tables

NTP                                          MEAN BODY WEIGHTS AND SURVIVAL TABLE                                 REPORT: EISRPT41  
LAB: Battelle Northwest                                INDIUM PHOSPHIDE                                           DATE: 10/28/99    
EXPERIMENT: 88124 TEST: 03                                                                                        TIME: 13:30:43    
                                                CAGES FROM 0000 TO LAST CAGE                                      PAGE:    1        
TEST TYPE: CHRONIC                                  ROUTE: RESPIRATORY EXPOSURE WHOLE BODY                        NTP:  C88124      
CONT: NO1-ES-25335                                                                                                CAS: 22398-80-7   
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               REASONS FOR REMOVAL:    ALL                                                                                          
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
               REMOVAL DATE RANGE:     ALL                                                                                          
                                                                                                                                    
               TREATMENT GROUPS:       INCLUDE ALL                                                                                  




NTP                                          MEAN BODY WEIGHTS AND SURVIVAL TABLE                                 REPORT: EISRPT41

LAB: BATTELLE NORTHWEST                               INDIUM PHOSPHIDE                                            DATE: 10/28/99


EXPERIMENT: 88124 TEST: 03                                                                                        TIME: 13:37:47



TEST TYPE: TWO YEAR                                 ROUTE: RESPIRATORY EX                                         NTP:  C88124

CONT: NO1-ES-25335                                                                                                CAS: 22398-80-7

                             MEAN BODY WEIGHTS AND SURVIVAL OF MALE RATS IN THE
                             TWO YEAR RESPIRATORY EX STUDY OF INDIUM PHOSPHIDE

==========================================================================================================
WEEK     CONTROL                0.03    MG/M3            0.1MG/M3 STOP            0.3MG/M3 STOP
         ----------------       ----------------         ----------------         ----------------
          AV.WT.     NO.       AV.WT.  PERCENT  NO.     AV.WT.  PERCENT  NO.     AV.WT.  PERCENT  NO.
         (GRAMS)     (A)       (GRAMS)  OF CNTL  (A)    (GRAMS)  OF CNTL  (A)    (GRAMS)  OF CNTL  (A)
=========================================================================================================

  B       114.6       60       114.7    100.1    60     113.5     99.0    60     113.9     99.4    60
  1       114.6       60       114.7    100.1    60     113.5     99.0    60     113.9     99.4    60
  4       208.9       60       209.3    100.2    60     209.3    100.2    60     209.4    100.2    60
  8       271.7       60       270.1     99.4    60     271.2     99.8    60     266.7     98.2    60
 12       312.4       60       312.2     99.9    60     313.8    100.4    60     308.2     98.7    60
 16       353.9       50 (I)   348.9     98.6    50 (I) 353.2     99.8    50 (I) 346.3     97.9    50 (I)
 21       377.4       49       376.2     99.7    50     378.5    100.3    50     369.5     97.9    50
 24       397.9       49       396.0     99.5    50     400.0    100.5    50     389.4     97.9    50
 28       415.0       49       411.9     99.3    50     417.7    100.7    50     404.6     97.5    50
 32       429.3       49       429.3    100.0    50     431.3    100.5    50     420.4     97.9    50
 36       442.2       49       442.4    100.0    50     444.3    100.5    50     434.2     98.2    50
 40       449.1       49       446.3     99.4    50     452.1    100.7    50     441.3     98.3    50
 44       457.4       49       458.7    100.3    49     465.3    101.7    50     453.5     99.1    50
 52       472.9       49       470.1     99.4    49     475.9    100.6    50     467.0     98.8    50
 56       474.7       49       475.1    100.1    49     482.4    101.6    50     469.1     98.8    50
 60       480.3       48       479.8     99.9    49     487.6    101.5    49     477.5     99.4    50
 64       477.9       48       478.5    100.1    49     484.4    101.4    48     477.1     99.8    50
 68       484.8       48       486.5    100.4    49     494.3    102.0    47     482.7     99.6    50
 72       483.7       46       486.3    100.5    49     493.9    102.1    46     481.4     99.5    50
 76       490.7       45       491.8    100.2    48     498.0    101.5    45     484.9     98.8    47
 80       499.1       42       495.4     99.3    48     505.4    101.3    43     485.8     97.3    45
 84       496.4       41       504.5    101.6    45     501.7    101.1    43     488.2     98.3    43
 88       498.8       40       497.5     99.7    45     495.8     99.4    42     488.9     98.0    42
 92       499.3       37       499.5    100.0    42     484.3     97.0    41     486.8     97.5    41
 94       501.0       34       497.8     99.4    42     499.7     99.7    36     486.0     97.0    40
 96       492.4       34       496.3    100.8    41     507.5    103.1    33     485.9     98.7    37
 98       498.0       32       492.3     98.9    38     507.9    102.0    32     489.6     98.3    32
100       494.2       31       490.8     99.3    36     505.4    102.3    31     492.4     99.6    30
102       487.3       28       490.6    100.7    32     503.4    103.3    29     486.0     99.7    29
104       478.3       27       485.4    101.5    29     493.1    103.1    29     471.3     98.5    29

TERM. SAC.            27                         29                       29                       26


==========================================================================================================


    (A) NUMBER OF ANIMALS WEIGHED.  AT TERMINAL SACRIFICE, NUMBER
        OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
    (B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
    (I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
    (*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
         IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.

                             MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE RATS IN THE
                             TWO YEAR RESPIRATORY EX STUDY OF INDIUM PHOSPHIDE

==========================================================================================================
WEEK     CONTROL                0.03    MG/M3            0.1MG/M3 STOP            0.3MG/M3 STOP
         ----------------       ----------------         ----------------         ----------------
          AV.WT.     NO.       AV.WT.  PERCENT  NO.     AV.WT.  PERCENT  NO.     AV.WT.  PERCENT  NO.
         (GRAMS)     (A)       (GRAMS)  OF CNTL  (A)    (GRAMS)  OF CNTL  (A)    (GRAMS)  OF CNTL  (A)
=========================================================================================================

  B        96.2       60        95.4     99.2    60      94.8     98.5    60      95.2     99.0    60
  1        96.2       60        95.4     99.2    60      94.8     98.5    60      95.2     99.0    60
  4       143.0       60       143.3    100.2    59     141.7     99.1    60     141.9     99.2    60
  8       167.6       60       167.7    100.1    59     166.2     99.2    60     164.8     98.3    60
 12       184.3       60       181.7     98.6    59     181.8     98.6    60     178.9     97.1    60
 16       198.2       50 (I)   197.4     99.6    49 (I) 197.2     99.5    50 (I) 198.2    100.0    50 (I)
 21       208.2       49       207.9     99.9    48     206.5     99.2    50     207.1     99.5    50
 24       215.8       49       215.9    100.0    48     213.6     99.0    50     214.9     99.6    50
 28       224.1       49       221.4     98.8    48     221.2     98.7    50     221.0     98.6    49
 32       230.3       49       226.5     98.3    48     224.8     97.6    50     227.2     98.7    49
 36       238.8       49       233.1     97.6    48     233.2     97.7    49     233.5     97.8    49
 40       244.2       49       237.7     97.3    48     239.4     98.0    49     238.3     97.6    49
 44       251.8       49       248.7     98.8    48     249.8     99.2    49     247.7     98.4    49
 52       271.2       49       263.1     97.0    48     266.1     98.1    49     261.6     96.5    49
 56       277.5       49       271.4     97.8    48     274.3     98.8    49     269.0     96.9    49
 60       288.4       48       280.4     97.2    48     284.5     98.6    49     279.3     96.8    48
 64       287.6       48       284.2     98.8    47     287.2     99.9    48     282.9     98.4    48
 68       297.2       48       290.8     97.8    47     298.5    100.4    47     289.3     97.3    48
 72       303.2       47       301.2     99.3    45     305.4    100.7    47     297.5     98.1    48
 76       312.0       46       307.0     98.4    45     312.9    100.3    47     303.3     97.2    47
 80       316.1       44       314.8     99.6    44     320.8    101.5    47     309.3     97.8    46
 84       322.6       43       321.6     99.7    42     320.0     99.2    46     307.0     95.2    45
 88       326.5       41       320.4     98.1    40     322.7     98.8    44     312.6     95.7    40
 92       330.4       40       325.6     98.5    40     326.4     98.8    44     317.6     96.1    39
 94       328.8       40       327.3     99.5    40     329.2    100.1    43     320.6     97.5    36
 96       333.3       37       328.0     98.4    40     327.8     98.3    43     323.4     97.0    36
 98       332.9       36       328.7     98.7    39     333.1    100.1    40     325.9     97.9    36
100       334.9       35       332.0     99.1    35     336.7    100.5    38     326.4     97.5    36
102       337.2       35       328.8     97.5    35     336.1     99.7    38     324.7     96.3    36
104       335.6       34       328.4     97.9    32     336.0    100.1    36     317.5     94.6    34

TERM. SAC.            34                         31                       36                       34


==========================================================================================================


    (A) NUMBER OF ANIMALS WEIGHED.  AT TERMINAL SACRIFICE, NUMBER
        OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
    (B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
    (I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
    (*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
         IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.

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