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TDMS Study 89029-05 Pathology Tables

NTP                                        STATISTICAL ANALYSIS OF PRIMARY TUMORS                              REPORT: PEIRPT08
LAB: I. I. T. Research Inst                               MAGNETIC FIELDS (EMF)                                DATE: 01/28/98

EXPERIMENT: 89029 TEST: 05                                                                                     TIME: 10:35:17
TEST TYPE:  CHRONIC                             CAGES FROM 0000 TO LAST CAGE                                   PAGE:
CONT: NO1-ES-25351                              ROUTE: MAGNETIC FIELDS                                         NTP C#: C89029
PATHOLOGIST: KOVATCH, R.                                                                                       CAS: ELECTROMAG
                 

Rats(FISCHER 344)
-----------------------------
FOR ALL DOSES THE TUMOR RATES IN THE FOLLOWING TISSUES/ORGANS ARE BASED ON NUMBER OF TISSUES EXAMINED.
IN OTHER TISSUES/ORGANS, RATES ARE BASED ON NUMBER OF ANIMALS NECROPSIED.

                                                 ----------------
                                                 Adrenal Gland
                                                 Adrenal Medulla
                                                 Bone Marrow
                                                 Brain
                                                 Clitoral Gland
                                                 Clitoral/Preputial Gland
                                                 Epididymis
                                                 Heart
                                                 Islets, Pancreatic
                                                 Kidney
                                                 Liver
                                                 Lung
                                                 Nose
                                                 Ovary
                                                 Pancreas
                                                 Parathyroid Gland
                                                 Pituitary Gland
                                                 Preputial Gland
                                                 Prostate
                                                 Salivary Glands
                                                 Spleen
                                                 Testes
                                                 Thymus
                                                 Thyroid Gland
                                                 Urinary Bladder
NTP                                        STATISTICAL ANALYSIS OF PRIMARY TUMORS                              REPORT: PEIRPT08   
LAB: I. I. T. Research Inst                               MAGNETIC FIELDS (EMF)                                DATE: 01/28/98     
EXPERIMENT: 89029 TEST: 05                                                                                     TIME: 10:35:17     
TEST TYPE:  CHRONIC                             CAGES FROM 0000 TO LAST CAGE                                   PAGE:              
CONT: NO1-ES-25351                              ROUTE: MAGNETIC FIELDS                                         NTP C#: C89029     
PATHOLOGIST: KOVATCH, R.                                                                                       CAS: ELECTROMAG    



SUMMARY OF STATISTICALLY SIGNIFICANT (P<=.05) RESULTS
IN THE ANALYSIS OF               MAGNETIC FIELDS (EMF)
===============================================================

Male Rats
------------
Organ                                 Morphology
-----                                 ----------
All Organs                             Leukemia: Lymphocytic, Monocytic, Mononuclear, or Undifferentiated
===============================================================
Female Rats
------------
Organ                                  Morphology
-----                                  ----------
Adrenal Cortex                         Adenoma
===============================================================
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 1
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)        -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Adrenal Cortex                                                                                                                   |
|     Adenoma                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/99 (0%)                1/100 (1%)   |           6/100 (6%)               0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                  0.0%                     1.2%         |           7.0%                     0.0%            |
|TERMINAL (d)       |                  0/57 (0%)                1/59 (2%)    |           4/59 (7%)                0/58 (0%)       |
|FIRST INCIDENCE    |                  ---                      736 (T)      |           597                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.507      |                                    P=0.021N*       |
|POLY 3             |                                           P=0.500      |                                    P=0.020N*       |
|POLY 1.5           |                                           P=0.500      |                                    P=0.019N*       |
|POLY 6             |                                           P=0.500      |                                    P=0.020N*       |
|LOGISTIC REGRESSION|                                           P=0.507      |                                    P=0.020N*       |
|COCH-ARM / FISHERS |                                           P=0.503      |                                    P=0.014N*       |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Adrenal Medulla                                                                                                                  |
|     Pheochromocytoma Benign                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  24/98 (24%)              33/95 (35%)  |           7/96 (7%)                3/97 (3%)       |
|POLY-3 ADJUSTED (b)|                  27.8%                    39.9%        |           8.5%                     3.7%            |
|TERMINAL (d)       |                  17/57 (30%)              19/56 (34%)  |           6/56 (11%)               2/58 (3%)       |
|FIRST INCIDENCE    |                  619                      552          |           655                      727             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.107      |                                    P=0.156N        |
|POLY 3             |                                           P=0.063      |                                    P=0.164N        |
|POLY 1.5           |                                           P=0.068      |                                    P=0.165N        |
|POLY 6             |                                           P=0.065      |                                    P=0.159N        |
|LOGISTIC REGRESSION|                                           P=0.057      |                                    P=0.152N        |
|COCH-ARM / FISHERS |                                           P=0.080      |                                    P=0.161N        |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 2
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Adrenal Medulla                                                                                                                  |
|     Pheochromocytoma Complex                                                                                                    |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/98 (0%)                0/95 (0%)    |           0/96 (0%)                2/97 (2%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           0.0%                     2.4%            |
|TERMINAL (d)       |                  0/57 (0%)                0/56 (0%)    |           0/56 (0%)                1/58 (2%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           ---                      645             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.239         |
|POLY 3             |                                           (e)          |                                    P=0.239         |
|POLY 1.5           |                                           (e)          |                                    P=0.239         |
|POLY 6             |                                           (e)          |                                    P=0.240         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.240         |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.251         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Adrenal Medulla                                                                                                                  |
|     Pheochromocytoma Malignant                                                                                                  |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  2/98 (2%)                2/95 (2%)    |           0/96 (0%)                0/97 (0%)       |
|POLY-3 ADJUSTED (b)|                  2.4%                     2.5%         |           0.0%                     0.0%            |
|TERMINAL (d)       |                  2/57 (4%)                1/56 (2%)    |           0/56 (0%)                0/58 (0%)       |
|FIRST INCIDENCE    |                  736 (T)                  677          |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.688      |                                    (e)             |
|POLY 3             |                                           P=0.676      |                                    (e)             |
|POLY 1.5           |                                           P=0.679      |                                    (e)             |
|POLY 6             |                                           P=0.676      |                                    (e)             |
|LOGISTIC REGRESSION|                                           P=0.670      |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.678      |                                    (e)             |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 3
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Adrenal Medulla                                                                                                                  |
|     Pheochromocytoma: Benign, Complex, Malignant, NOS                                                                           |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  26/98 (27%)              35/95 (37%)  |           7/96 (7%)                5/97 (5%)       |
|POLY-3 ADJUSTED (b)|                  30.1%                    42.2%        |           8.5%                     6.1%            |
|TERMINAL (d)       |                  19/57 (33%)              20/56 (36%)  |           6/56 (11%)               3/58 (5%)       |
|FIRST INCIDENCE    |                  619                      552          |           655                      645             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.111      |                                    P=0.371N        |
|POLY 3             |                                           P=0.066      |                                    P=0.381N        |
|POLY 1.5           |                                           P=0.070      |                                    P=0.382N        |
|POLY 6             |                                           P=0.070      |                                    P=0.371N        |
|LOGISTIC REGRESSION|                                           P=0.057      |                                    P=0.372N        |
|COCH-ARM / FISHERS |                                           P=0.083      |                                    P=0.376N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Brain                                                                                                                            |
|     Oligodendroglioma, Glioma, or Astrocytoma                                                                                   |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  2/100 (2%)               1/100 (1%)   |           2/100 (2%)               0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                  2.3%                     1.2%         |           2.3%                     0.0%            |
|TERMINAL (d)       |                  0/57 (0%)                0/59 (0%)    |           1/59 (2%)                0/58 (0%)       |
|FIRST INCIDENCE    |                  645                      559          |           547                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.515N     |                                    P=0.248N        |
|POLY 3             |                                           P=0.510N     |                                    P=0.248N        |
|POLY 1.5           |                                           P=0.507N     |                                    P=0.245N        |
|POLY 6             |                                           P=0.511N     |                                    P=0.248N        |
|LOGISTIC REGRESSION|                                           P=0.477N     |                                    P=0.214N        |
|COCH-ARM / FISHERS |                                           P=0.500N     |                                    P=0.249N        |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 4
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Clitoral/Preputial Gland                                                                                                         |
|     Adenoma                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  13/100 (13%)             10/100 (10%) |           11/90 (12%)              11/94 (12%)     |
|POLY-3 ADJUSTED (b)|                  15.0%                    11.8%        |           14.1%                    13.5%           |
|TERMINAL (d)       |                  7/57 (12%)               7/59 (12%)   |           7/56 (13%)               8/56 (14%)      |
|FIRST INCIDENCE    |                  649                      586          |           597                      430             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.321N     |                                    P=0.587N        |
|POLY 3             |                                           P=0.348N     |                                    P=0.547N        |
|POLY 1.5           |                                           P=0.342N     |                                    P=0.548N        |
|POLY 6             |                                           P=0.349N     |                                    P=0.540N        |
|LOGISTIC REGRESSION|                                           P=0.348N     |                                    P=0.551N        |
|COCH-ARM / FISHERS |                                           P=0.329N     |                                    P=0.547N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Clitoral/Preputial Gland                                                                                                         |
|     Carcinoma or Adenoma                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  13/100 (13%)             12/100 (12%) |           11/90 (12%)              11/94 (12%)     |
|POLY-3 ADJUSTED (b)|                  15.0%                    14.0%        |           14.1%                    13.5%           |
|TERMINAL (d)       |                  7/57 (12%)               7/59 (12%)   |           7/56 (13%)               8/56 (14%)      |
|FIRST INCIDENCE    |                  649                      558          |           597                      430             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.493N     |                                    P=0.587N        |
|POLY 3             |                                           P=0.510N     |                                    P=0.547N        |
|POLY 1.5           |                                           P=0.508N     |                                    P=0.548N        |
|POLY 6             |                                           P=0.504N     |                                    P=0.540N        |
|LOGISTIC REGRESSION|                                           P=0.514N     |                                    P=0.551N        |
|COCH-ARM / FISHERS |                                           P=0.500N     |                                    P=0.547N        |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 5
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Islets, Pancreatic                                                                                                               |
|     Adenoma                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  3/99 (3%)                2/100 (2%)   |           1/100 (1%)               1/99 (1%)       |
|POLY-3 ADJUSTED (b)|                  3.5%                     2.4%         |           1.2%                     1.2%            |
|TERMINAL (d)       |                  2/57 (4%)                0/59 (0%)    |           1/59 (2%)                1/58 (2%)       |
|FIRST INCIDENCE    |                  714                      675          |           737 (T)                  737 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.480N     |                                    P=0.757         |
|POLY 3             |                                           P=0.506N     |                                    P=0.758         |
|POLY 1.5           |                                           P=0.503N     |                                    P=0.758         |
|POLY 6             |                                           P=0.506N     |                                    P=0.759         |
|LOGISTIC REGRESSION|                                           P=0.506N     |                                    P=0.757         |
|COCH-ARM / FISHERS |                                           P=0.495N     |                                    P=0.749         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Islets, Pancreatic                                                                                                               |
|     Carcinoma                                                                                                                   |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  1/99 (1%)                3/100 (3%)   |           1/100 (1%)               1/99 (1%)       |
|POLY-3 ADJUSTED (b)|                  1.2%                     3.6%         |           1.2%                     1.2%            |
|TERMINAL (d)       |                  1/57 (2%)                2/59 (3%)    |           1/59 (2%)                0/58 (0%)       |
|FIRST INCIDENCE    |                  736 (T)                  715          |           737 (T)                  729             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.325      |                                    P=0.758         |
|POLY 3             |                                           P=0.303      |                                    P=0.758         |
|POLY 1.5           |                                           P=0.305      |                                    P=0.758         |
|POLY 6             |                                           P=0.302      |                                    P=0.759         |
|LOGISTIC REGRESSION|                                           P=0.310      |                                    P=0.762         |
|COCH-ARM / FISHERS |                                           P=0.314      |                                    P=0.749         |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 6
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Islets, Pancreatic                                                                                                               |
|     Carcinoma or Adenoma                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  4/99 (4%)                5/100 (5%)   |           2/100 (2%)               2/99 (2%)       |
|POLY-3 ADJUSTED (b)|                  4.7%                     5.9%         |           2.3%                     2.4%            |
|TERMINAL (d)       |                  3/57 (5%)                2/59 (3%)    |           2/59 (3%)                1/58 (2%)       |
|FIRST INCIDENCE    |                  714                      675          |           737 (T)                  729             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.528      |                                    P=0.688         |
|POLY 3             |                                           P=0.494      |                                    P=0.687         |
|POLY 1.5           |                                           P=0.498      |                                    P=0.687         |
|POLY 6             |                                           P=0.495      |                                    P=0.689         |
|LOGISTIC REGRESSION|                                           P=0.491      |                                    P=0.694N        |
|COCH-ARM / FISHERS |                                           P=0.506      |                                    P=0.686         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lung                                                                                                                             |
|     Alveolar/Bronchiolar Adenoma                                                                                                |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  3/100 (3%)               0/100 (0%)   |           3/100 (3%)               0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                  3.5%                     0.0%         |           3.5%                     0.0%            |
|TERMINAL (d)       |                  3/57 (5%)                0/59 (0%)    |           3/59 (5%)                0/58 (0%)       |
|FIRST INCIDENCE    |                  736 (T)                  ---          |           737 (T)                  ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.116N     |                                    P=0.125N        |
|POLY 3             |                                           P=0.127N     |                                    P=0.126N        |
|POLY 1.5           |                                           P=0.125N     |                                    P=0.125N        |
|POLY 6             |                                           P=0.127N     |                                    P=0.125N        |
|LOGISTIC REGRESSION|                                           (e)          |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.123N     |                                    P=0.123N        |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 7
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lung                                                                                                                             |
|     Alveolar/Bronchiolar Carcinoma or Alveolar/Bronchiolar                                                                      |
|     Adenoma                                                                                                                     |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  3/100 (3%)               0/100 (0%)   |           4/100 (4%)               0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                  3.5%                     0.0%         |           4.7%                     0.0%            |
|TERMINAL (d)       |                  3/57 (5%)                0/59 (0%)    |           3/59 (5%)                0/58 (0%)       |
|FIRST INCIDENCE    |                  736 (T)                  ---          |           610                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.116N     |                                    P=0.068N        |
|POLY 3             |                                           P=0.127N     |                                    P=0.068N        |
|POLY 1.5           |                                           P=0.125N     |                                    P=0.067N        |
|POLY 6             |                                           P=0.127N     |                                    P=0.067N        |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.067N        |
|COCH-ARM / FISHERS |                                           P=0.123N     |                                    P=0.061N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Mammary Gland                                                                                                                    |
|     Adenoma                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/100 (0%)               0/100 (0%)   |           1/100 (1%)               2/100 (2%)      |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           1.2%                     2.4%            |
|TERMINAL (d)       |                  0/57 (0%)                0/59 (0%)    |           1/59 (2%)                2/58 (3%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           737 (T)                  737 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.494         |
|POLY 3             |                                           (e)          |                                    P=0.495         |
|POLY 1.5           |                                           (e)          |                                    P=0.496         |
|POLY 6             |                                           (e)          |                                    P=0.496         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.494         |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.500         |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 8
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Mammary Gland                                                                                                                    |
|     Carcinoma                                                                                                                   |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/100 (0%)               0/100 (0%)   |           2/100 (2%)               2/100 (2%)      |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           2.3%                     2.4%            |
|TERMINAL (d)       |                  0/57 (0%)                0/59 (0%)    |           2/59 (3%)                1/58 (2%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           737 (T)                  591             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.684         |
|POLY 3             |                                           (e)          |                                    P=0.689         |
|POLY 1.5           |                                           (e)          |                                    P=0.689         |
|POLY 6             |                                           (e)          |                                    P=0.691         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.689         |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.689N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Mammary Gland                                                                                                                    |
|     Carcinoma or Adenoma                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/100 (0%)               0/100 (0%)   |           3/100 (3%)               4/100 (4%)      |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           3.5%                     4.8%            |
|TERMINAL (d)       |                  0/57 (0%)                0/59 (0%)    |           3/59 (5%)                3/58 (5%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           737 (T)                  591             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.489         |
|POLY 3             |                                           (e)          |                                    P=0.493         |
|POLY 1.5           |                                           (e)          |                                    P=0.494         |
|POLY 6             |                                           (e)          |                                    P=0.496         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.490         |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.500         |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 9
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Mammary Gland                                                                                                                    |
|     Fibroadenoma                                                                                                                |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  6/100 (6%)               8/100 (8%)   |           56/100 (56%)             51/100 (51%)    |
|POLY-3 ADJUSTED (b)|                  7.0%                     9.5%         |           62.5%                    57.8%           |
|TERMINAL (d)       |                  6/57 (11%)               5/59 (9%)    |           39/59 (66%)              36/58 (62%)     |
|FIRST INCIDENCE    |                  736 (T)                  600          |           543                      430             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.408      |                                    P=0.338N        |
|POLY 3             |                                           P=0.380      |                                    P=0.306N        |
|POLY 1.5           |                                           P=0.383      |                                    P=0.306N        |
|POLY 6             |                                           P=0.385      |                                    P=0.288N        |
|LOGISTIC REGRESSION|                                           P=0.376      |                                    P=0.340N        |
|COCH-ARM / FISHERS |                                           P=0.391      |                                    P=0.285N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Mammary Gland                                                                                                                    |
|     Fibroma, Fibroadenoma or Adenoma                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  6/100 (6%)               8/100 (8%)   |           56/100 (56%)             52/100 (52%)    |
|POLY-3 ADJUSTED (b)|                  7.0%                     9.5%         |           62.5%                    58.9%           |
|TERMINAL (d)       |                  6/57 (11%)               5/59 (9%)    |           39/59 (66%)              37/58 (64%)     |
|FIRST INCIDENCE    |                  736 (T)                  600          |           543                      430             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.408      |                                    P=0.387N        |
|POLY 3             |                                           P=0.380      |                                    P=0.364N        |
|POLY 1.5           |                                           P=0.383      |                                    P=0.361N        |
|POLY 6             |                                           P=0.385      |                                    P=0.347N        |
|LOGISTIC REGRESSION|                                           P=0.376      |                                    P=0.397N        |
|COCH-ARM / FISHERS |                                           P=0.391      |                                    P=0.335N        |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 10
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Mammary Gland                                                                                                                    |
|     Fibroma, Fibroadenoma, Carcinoma, or Adenoma                                                                                |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  6/100 (6%)               8/100 (8%)   |           58/100 (58%)             54/100 (54%)    |
|POLY-3 ADJUSTED (b)|                  7.0%                     9.5%         |           64.7%                    60.8%           |
|TERMINAL (d)       |                  6/57 (11%)               5/59 (9%)    |           41/59 (70%)              38/58 (66%)     |
|FIRST INCIDENCE    |                  736 (T)                  600          |           543                      430             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.408      |                                    P=0.389N        |
|POLY 3             |                                           P=0.380      |                                    P=0.346N        |
|POLY 1.5           |                                           P=0.383      |                                    P=0.351N        |
|POLY 6             |                                           P=0.385      |                                    P=0.316N        |
|LOGISTIC REGRESSION|                                           P=0.376      |                                    P=0.400N        |
|COCH-ARM / FISHERS |                                           P=0.391      |                                    P=0.335N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Ovary                                                                                                                            |
|     Tubulostromal Adenoma                                                                                                       |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                                                        |           3/100 (3%)               2/99 (2%)       |
|POLY-3 ADJUSTED (b)|                                                        |           3.5%                     2.4%            |
|TERMINAL (d)       |                                                        |           2/59 (3%)                2/58 (3%)       |
|FIRST INCIDENCE    |                                                        |           736                      737 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                                        |                                    P=0.509N        |
|POLY 3             |                                                        |                                    P=0.515N        |
|POLY 1.5           |                                                        |                                    P=0.513N        |
|POLY 6             |                                                        |                                    P=0.511N        |
|LOGISTIC REGRESSION|                                                        |                                    P=0.507N        |
|COCH-ARM / FISHERS |                                                        |                                    P=0.505N        |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 11
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Pancreas                                                                                                                         |
|     Adenoma                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  3/98 (3%)                2/100 (2%)   |           0/100 (0%)               0/99 (0%)       |
|POLY-3 ADJUSTED (b)|                  3.5%                     2.4%         |           0.0%                     0.0%            |
|TERMINAL (d)       |                  2/57 (4%)                1/59 (2%)    |           0/59 (0%)                0/58 (0%)       |
|FIRST INCIDENCE    |                  658                      621          |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.504N     |                                    (e)             |
|POLY 3             |                                           P=0.505N     |                                    (e)             |
|POLY 1.5           |                                           P=0.500N     |                                    (e)             |
|POLY 6             |                                           P=0.507N     |                                    (e)             |
|LOGISTIC REGRESSION|                                           P=0.497N     |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.490N     |                                    (e)             |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Pituitary Gland: Pars Distalis or Unspecified Site                                                                               |
|     Adenoma                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  34/98 (35%)              40/98 (41%)  |           61/99 (62%)              62/98 (63%)     |
|POLY-3 ADJUSTED (b)|                  38.8%                    46.0%        |           65.8%                    68.1%           |
|TERMINAL (d)       |                  23/57 (40%)              28/58 (48%)  |           40/59 (68%)              37/58 (64%)     |
|FIRST INCIDENCE    |                  579                      470          |           533                      430             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.245      |                                    P=0.453         |
|POLY 3             |                                           P=0.206      |                                    P=0.429         |
|POLY 1.5           |                                           P=0.215      |                                    P=0.438         |
|POLY 6             |                                           P=0.202      |                                    P=0.435         |
|LOGISTIC REGRESSION|                                           P=0.203      |                                    P=0.437         |
|COCH-ARM / FISHERS |                                           P=0.231      |                                    P=0.463         |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 12
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Pituitary Gland: Pars Distalis or Unspecified Site                                                                               |
|     Carcinoma                                                                                                                   |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/98 (0%)                3/98 (3%)    |           3/99 (3%)                2/98 (2%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     3.6%         |           3.5%                     2.4%            |
|TERMINAL (d)       |                  0/57 (0%)                1/58 (2%)    |           2/59 (3%)                1/58 (2%)       |
|FIRST INCIDENCE    |                  ---                      645          |           655                      641             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.124      |                                    P=0.512N        |
|POLY 3             |                                           P=0.119      |                                    P=0.513N        |
|POLY 1.5           |                                           P=0.120      |                                    P=0.512N        |
|POLY 6             |                                           P=0.119      |                                    P=0.510N        |
|LOGISTIC REGRESSION|                                           P=0.120      |                                    P=0.509N        |
|COCH-ARM / FISHERS |                                           P=0.123      |                                    P=0.505N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Pituitary Gland: Pars Distalis or Unspecified Site                                                                               |
|     Carcinoma or Adenoma                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  34/98 (35%)              43/98 (44%)  |           64/99 (65%)              64/98 (65%)     |
|POLY-3 ADJUSTED (b)|                  38.8%                    49.2%        |           68.8%                    70.1%           |
|TERMINAL (d)       |                  23/57 (40%)              29/58 (50%)  |           42/59 (71%)              38/58 (66%)     |
|FIRST INCIDENCE    |                  579                      470          |           533                      430             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.139      |                                    P=0.496         |
|POLY 3             |                                           P=0.103      |                                    P=0.492         |
|POLY 1.5           |                                           P=0.109      |                                    P=0.499         |
|POLY 6             |                                           P=0.102      |                                    P=0.502         |
|LOGISTIC REGRESSION|                                           P=0.101      |                                    P=0.491         |
|COCH-ARM / FISHERS |                                           P=0.121      |                                    P=0.521         |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 13
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Skin                                                                                                                             |
|     Basal Cell Adenoma                                                                                                          |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  3/100 (3%)               3/100 (3%)   |           0/100 (0%)               1/100 (1%)      |
|POLY-3 ADJUSTED (b)|                  3.5%                     3.6%         |           0.0%                     1.2%            |
|TERMINAL (d)       |                  2/57 (4%)                2/59 (3%)    |           0/59 (0%)                1/58 (2%)       |
|FIRST INCIDENCE    |                  659                      582          |           ---                      737 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.659N     |                                    P=0.497         |
|POLY 3             |                                           P=0.653      |                                    P=0.500         |
|POLY 1.5           |                                           P=0.655      |                                    P=0.500         |
|POLY 6             |                                           P=0.653      |                                    P=0.500         |
|LOGISTIC REGRESSION|                                           P=0.656      |                                    P=0.497         |
|COCH-ARM / FISHERS |                                           P=0.659N     |                                    P=0.500         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Skin                                                                                                                             |
|     Basal Cell Adenoma, Basosquamous Tumor Benign, or                                                                           |
|     Trichoepithelioma                                                                                                           |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  3/100 (3%)               3/100 (3%)   |           0/100 (0%)               1/100 (1%)      |
|POLY-3 ADJUSTED (b)|                  3.5%                     3.6%         |           0.0%                     1.2%            |
|TERMINAL (d)       |                  2/57 (4%)                2/59 (3%)    |           0/59 (0%)                1/58 (2%)       |
|FIRST INCIDENCE    |                  659                      582          |           ---                      737 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.659N     |                                    P=0.497         |
|POLY 3             |                                           P=0.653      |                                    P=0.500         |
|POLY 1.5           |                                           P=0.655      |                                    P=0.500         |
|POLY 6             |                                           P=0.653      |                                    P=0.500         |
|LOGISTIC REGRESSION|                                           P=0.656      |                                    P=0.497         |
|COCH-ARM / FISHERS |                                           P=0.659N     |                                    P=0.500         |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 14
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Skin                                                                                                                             |
|     Basal Cell Carcinoma, Basal Cell Adenoma, Basosquamous                                                                      |
|     Tumor (benign, malignant or NOS), or Trichoepithelioma                                                                      |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  3/100 (3%)               3/100 (3%)   |           0/100 (0%)               1/100 (1%)      |
|POLY-3 ADJUSTED (b)|                  3.5%                     3.6%         |           0.0%                     1.2%            |
|TERMINAL (d)       |                  2/57 (4%)                2/59 (3%)    |           0/59 (0%)                1/58 (2%)       |
|FIRST INCIDENCE    |                  659                      582          |           ---                      737 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.659N     |                                    P=0.497         |
|POLY 3             |                                           P=0.653      |                                    P=0.500         |
|POLY 1.5           |                                           P=0.655      |                                    P=0.500         |
|POLY 6             |                                           P=0.653      |                                    P=0.500         |
|LOGISTIC REGRESSION|                                           P=0.656      |                                    P=0.497         |
|COCH-ARM / FISHERS |                                           P=0.659N     |                                    P=0.500         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Skin                                                                                                                             |
|     Basal or Sq. Cell Carcinoma, Carcinoma, Basosq. Tumor                                                                       |
|     (M or B), Basal Cell Adenoma, Adenoma, Papilloma, Sq Papilloma, Keratoacanthoma, Trichoepitheliom                           |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  14/100 (14%)             12/100 (12%) |           1/100 (1%)               2/100 (2%)      |
|POLY-3 ADJUSTED (b)|                  16.1%                    14.0%        |           1.2%                     2.4%            |
|TERMINAL (d)       |                  10/57 (18%)              8/59 (14%)   |           1/59 (2%)                2/58 (3%)       |
|FIRST INCIDENCE    |                  627                      470          |           737 (T)                  737 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.400N     |                                    P=0.494         |
|POLY 3             |                                           P=0.428N     |                                    P=0.495         |
|POLY 1.5           |                                           P=0.425N     |                                    P=0.496         |
|POLY 6             |                                           P=0.425N     |                                    P=0.496         |
|LOGISTIC REGRESSION|                                           P=0.433N     |                                    P=0.494         |
|COCH-ARM / FISHERS |                                           P=0.417N     |                                    P=0.500         |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 15
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Skin                                                                                                                             |
|     Fibroma                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  12/100 (12%)             12/100 (12%) |           4/100 (4%)               1/100 (1%)      |
|POLY-3 ADJUSTED (b)|                  13.9%                    14.2%        |           4.7%                     1.2%            |
|TERMINAL (d)       |                  9/57 (16%)               8/59 (14%)   |           2/59 (3%)                1/58 (2%)       |
|FIRST INCIDENCE    |                  617                      586          |           660                      737 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.563N     |                                    P=0.193N        |
|POLY 3             |                                           P=0.568      |                                    P=0.192N        |
|POLY 1.5           |                                           P=0.573      |                                    P=0.189N        |
|POLY 6             |                                           P=0.570      |                                    P=0.192N        |
|LOGISTIC REGRESSION|                                           P=0.563      |                                    P=0.188N        |
|COCH-ARM / FISHERS |                                           P=0.586N     |                                    P=0.184N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Skin                                                                                                                             |
|     Fibroma, Fibrosarcoma, Sarcoma, Myxoma, Myxosarcoma,                                                                        |
|     or Fibrous Histiocytoma                                                                                                     |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  13/100 (13%)             14/100 (14%) |           6/100 (6%)               2/100 (2%)      |
|POLY-3 ADJUSTED (b)|                  15.0%                    16.5%        |           6.9%                     2.4%            |
|TERMINAL (d)       |                  9/57 (16%)               10/59 (17%)  |           2/59 (3%)                1/58 (2%)       |
|FIRST INCIDENCE    |                  617                      586          |           613                      602             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.526      |                                    P=0.150N        |
|POLY 3             |                                           P=0.477      |                                    P=0.148N        |
|POLY 1.5           |                                           P=0.484      |                                    P=0.146N        |
|POLY 6             |                                           P=0.477      |                                    P=0.149N        |
|LOGISTIC REGRESSION|                                           P=0.474      |                                    P=0.137N        |
|COCH-ARM / FISHERS |                                           P=0.500      |                                    P=0.140N        |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 16
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Skin                                                                                                                             |
|     Keratoacanthoma                                                                                                             |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  10/100 (10%)             8/100 (8%)   |           1/100 (1%)               0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                  11.6%                    9.5%         |           1.2%                     0.0%            |
|TERMINAL (d)       |                  7/57 (12%)               6/59 (10%)   |           1/59 (2%)                0/58 (0%)       |
|FIRST INCIDENCE    |                  627                      557          |           737 (T)                  ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.384N     |                                    P=0.503N        |
|POLY 3             |                                           P=0.423N     |                                    P=0.508N        |
|POLY 1.5           |                                           P=0.416N     |                                    P=0.507N        |
|POLY 6             |                                           P=0.424N     |                                    P=0.507N        |
|LOGISTIC REGRESSION|                                           P=0.421N     |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.403N     |                                    P=0.500N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Skin                                                                                                                             |
|     Melanoma Malignant                                                                                                          |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/100 (0%)               2/100 (2%)   |           0/100 (0%)               0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                  0.0%                     2.4%         |           0.0%                     0.0%            |
|TERMINAL (d)       |                  0/57 (0%)                1/59 (2%)    |           0/59 (0%)                0/58 (0%)       |
|FIRST INCIDENCE    |                  ---                      552          |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.244      |                                    (e)             |
|POLY 3             |                                           P=0.237      |                                    (e)             |
|POLY 1.5           |                                           P=0.237      |                                    (e)             |
|POLY 6             |                                           P=0.237      |                                    (e)             |
|LOGISTIC REGRESSION|                                           P=0.249      |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.249      |                                    (e)             |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 17
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Skin                                                                                                                             |
|     Squamous Cell Carcinoma                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/100 (0%)               2/100 (2%)   |           0/100 (0%)               0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                  0.0%                     2.4%         |           0.0%                     0.0%            |
|TERMINAL (d)       |                  0/57 (0%)                1/59 (2%)    |           0/59 (0%)                0/58 (0%)       |
|FIRST INCIDENCE    |                  ---                      470          |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.244      |                                    (e)             |
|POLY 3             |                                           P=0.237      |                                    (e)             |
|POLY 1.5           |                                           P=0.237      |                                    (e)             |
|POLY 6             |                                           P=0.237      |                                    (e)             |
|LOGISTIC REGRESSION|                                           P=0.258      |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.249      |                                    (e)             |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Skin                                                                                                                             |
|     Squamous Cell Papilloma, Papilloma, Squamous Cell                                                                           |
|     Carcinoma or Keratoacanthoma                                                                                                |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  11/100 (11%)             10/100 (10%) |           1/100 (1%)               1/100 (1%)      |
|POLY-3 ADJUSTED (b)|                  12.7%                    11.7%        |           1.2%                     1.2%            |
|TERMINAL (d)       |                  8/57 (14%)               7/59 (12%)   |           1/59 (2%)                1/58 (2%)       |
|FIRST INCIDENCE    |                  627                      470          |           737 (T)                  737 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.478N     |                                    P=0.757         |
|POLY 3             |                                           P=0.514N     |                                    P=0.758         |
|POLY 1.5           |                                           P=0.510N     |                                    P=0.759         |
|POLY 6             |                                           P=0.513N     |                                    P=0.759         |
|LOGISTIC REGRESSION|                                           P=0.517N     |                                    P=0.757         |
|COCH-ARM / FISHERS |                                           P=0.500N     |                                    P=0.751N        |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 18
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Skin                                                                                                                             |
|     Squamous Cell Papilloma, Papilloma, or Keratoacanthoma                                                                      |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  11/100 (11%)             8/100 (8%)   |           1/100 (1%)               1/100 (1%)      |
|POLY-3 ADJUSTED (b)|                  12.7%                    9.5%         |           1.2%                     1.2%            |
|TERMINAL (d)       |                  8/57 (14%)               6/59 (10%)   |           1/59 (2%)                1/58 (2%)       |
|FIRST INCIDENCE    |                  627                      557          |           737 (T)                  737 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.297N     |                                    P=0.757         |
|POLY 3             |                                           P=0.333N     |                                    P=0.758         |
|POLY 1.5           |                                           P=0.327N     |                                    P=0.759         |
|POLY 6             |                                           P=0.333N     |                                    P=0.759         |
|LOGISTIC REGRESSION|                                           P=0.332N     |                                    P=0.757         |
|COCH-ARM / FISHERS |                                           P=0.315N     |                                    P=0.751N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Testes                                                                                                                           |
|     Adenoma                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  93/100 (93%)             89/100 (89%) |                                                    |
|POLY-3 ADJUSTED (b)|                  95.1%                    93.8%        |                                                    |
|TERMINAL (d)       |                  54/57 (95%)              57/59 (97%)  |                                                    |
|FIRST INCIDENCE    |                  476                      489          |                                                    |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.324N     |                                                    |
|POLY 3             |                                           P=0.460N     |                                                    |
|POLY 1.5           |                                           P=0.339N     |                                                    |
|POLY 6             |                                           P=0.622N     |                                                    |
|LOGISTIC REGRESSION|                                           P=0.320N     |                                                    |
|COCH-ARM / FISHERS |                                           P=0.230N     |                                                    |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 19
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Thymus                                                                                                                           |
|     Thymoma Benign                                                                                                              |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  2/97 (2%)                0/95 (0%)    |           0/95 (0%)                1/92 (1%)       |
|POLY-3 ADJUSTED (b)|                  2.4%                     0.0%         |           0.0%                     1.3%            |
|TERMINAL (d)       |                  2/55 (4%)                0/56 (0%)    |           0/56 (0%)                1/57 (2%)       |
|FIRST INCIDENCE    |                  736 (T)                  ---          |           ---                      737 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.235N     |                                    P=0.504         |
|POLY 3             |                                           P=0.255N     |                                    P=0.500         |
|POLY 1.5           |                                           P=0.252N     |                                    P=0.500         |
|POLY 6             |                                           P=0.254N     |                                    P=0.500         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.504         |
|COCH-ARM / FISHERS |                                           P=0.254N     |                                    P=0.492         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Thymus                                                                                                                           |
|     Thymoma: Benign, Malignant, NOS                                                                                             |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  2/97 (2%)                0/95 (0%)    |           0/95 (0%)                1/92 (1%)       |
|POLY-3 ADJUSTED (b)|                  2.4%                     0.0%         |           0.0%                     1.3%            |
|TERMINAL (d)       |                  2/55 (4%)                0/56 (0%)    |           0/56 (0%)                1/57 (2%)       |
|FIRST INCIDENCE    |                  736 (T)                  ---          |           ---                      737 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.235N     |                                    P=0.504         |
|POLY 3             |                                           P=0.255N     |                                    P=0.500         |
|POLY 1.5           |                                           P=0.252N     |                                    P=0.500         |
|POLY 6             |                                           P=0.254N     |                                    P=0.500         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.504         |
|COCH-ARM / FISHERS |                                           P=0.254N     |                                    P=0.492         |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 20
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Thyroid Gland: C-Cell                                                                                                            |
|     Adenoma                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  15/99 (15%)              18/100 (18%) |           15/100 (15%)             16/100 (16%)    |
|POLY-3 ADJUSTED (b)|                  17.2%                    21.5%        |           17.3%                    19.0%           |
|TERMINAL (d)       |                  7/57 (12%)               16/59 (27%)  |           12/59 (20%)              14/58 (24%)     |
|FIRST INCIDENCE    |                  583                      725          |           561                      632             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.376      |                                    P=0.482         |
|POLY 3             |                                           P=0.305      |                                    P=0.463         |
|POLY 1.5           |                                           P=0.329      |                                    P=0.474         |
|POLY 6             |                                           P=0.280      |                                    P=0.459         |
|LOGISTIC REGRESSION|                                           P=0.330      |                                    P=0.479         |
|COCH-ARM / FISHERS |                                           P=0.364      |                                    P=0.500         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Thyroid Gland: C-Cell                                                                                                            |
|     Carcinoma                                                                                                                   |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  1/99 (1%)                5/100 (5%)   |           5/100 (5%)               6/100 (6%)      |
|POLY-3 ADJUSTED (b)|                  1.2%                     5.9%         |           5.9%                     7.1%            |
|TERMINAL (d)       |                  1/57 (2%)                4/59 (7%)    |           4/59 (7%)                5/58 (9%)       |
|FIRST INCIDENCE    |                  736 (T)                  666          |           710                      627             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.113      |                                    P=0.495         |
|POLY 3             |                                           P=0.103      |                                    P=0.489         |
|POLY 1.5           |                                           P=0.105      |                                    P=0.491         |
|POLY 6             |                                           P=0.103      |                                    P=0.493         |
|LOGISTIC REGRESSION|                                           P=0.104      |                                    P=0.491         |
|COCH-ARM / FISHERS |                                           P=0.108      |                                    P=0.500         |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 21
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Thyroid Gland: C-Cell                                                                                                            |
|     Carcinoma or Adenoma                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  16/99 (16%)              22/100 (22%) |           19/100 (19%)             22/100 (22%)    |
|POLY-3 ADJUSTED (b)|                  18.4%                    26.1%        |           21.9%                    26.1%           |
|TERMINAL (d)       |                  8/57 (14%)               19/59 (32%)  |           15/59 (25%)              19/58 (33%)     |
|FIRST INCIDENCE    |                  583                      666          |           561                      627             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.206      |                                    P=0.343         |
|POLY 3             |                                           P=0.147      |                                    P=0.322         |
|POLY 1.5           |                                           P=0.165      |                                    P=0.334         |
|POLY 6             |                                           P=0.130      |                                    P=0.319         |
|LOGISTIC REGRESSION|                                           P=0.164      |                                    P=0.337         |
|COCH-ARM / FISHERS |                                           P=0.193      |                                    P=0.363         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Uterus                                                                                                                           |
|     Adenoma                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                                                        |           0/100 (0%)               2/100 (2%)      |
|POLY-3 ADJUSTED (b)|                                                        |           0.0%                     2.4%            |
|TERMINAL (d)       |                                                        |           0/59 (0%)                2/58 (3%)       |
|FIRST INCIDENCE    |                                                        |           ---                      737 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                                        |                                    P=0.235         |
|POLY 3             |                                                        |                                    P=0.236         |
|POLY 1.5           |                                                        |                                    P=0.237         |
|POLY 6             |                                                        |                                    P=0.236         |
|LOGISTIC REGRESSION|                                                        |                                    P=0.235         |
|COCH-ARM / FISHERS |                                                        |                                    P=0.249         |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 22
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Uterus                                                                                                                           |
|     Leiomyosarcoma                                                                                                              |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                                                        |           2/100 (2%)               0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                                                        |           2.3%                     0.0%            |
|TERMINAL (d)       |                                                        |           0/59 (0%)                0/58 (0%)       |
|FIRST INCIDENCE    |                                                        |           533                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                                        |                                    P=0.248N        |
|POLY 3             |                                                        |                                    P=0.249N        |
|POLY 1.5           |                                                        |                                    P=0.246N        |
|POLY 6             |                                                        |                                    P=0.249N        |
|LOGISTIC REGRESSION|                                                        |                                    P=0.189N        |
|COCH-ARM / FISHERS |                                                        |                                    P=0.249N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Uterus                                                                                                                           |
|     Polyp Stromal                                                                                                               |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                                                        |           13/100 (13%)             12/100 (12%)    |
|POLY-3 ADJUSTED (b)|                                                        |           15.1%                    14.2%           |
|TERMINAL (d)       |                                                        |           9/59 (15%)               10/58 (17%)     |
|FIRST INCIDENCE    |                                                        |           620                      480             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                                        |                                    P=0.516N        |
|POLY 3             |                                                        |                                    P=0.525N        |
|POLY 1.5           |                                                        |                                    P=0.518N        |
|POLY 6             |                                                        |                                    P=0.527N        |
|LOGISTIC REGRESSION|                                                        |                                    P=0.520N        |
|COCH-ARM / FISHERS |                                                        |                                    P=0.500N        |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 23
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Uterus                                                                                                                           |
|     Sarcoma Stromal or Polyp Stromal                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                                                        |           13/100 (13%)             12/100 (12%)    |
|POLY-3 ADJUSTED (b)|                                                        |           15.1%                    14.2%           |
|TERMINAL (d)       |                                                        |           9/59 (15%)               10/58 (17%)     |
|FIRST INCIDENCE    |                                                        |           620                      480             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                                        |                                    P=0.516N        |
|POLY 3             |                                                        |                                    P=0.525N        |
|POLY 1.5           |                                                        |                                    P=0.518N        |
|POLY 6             |                                                        |                                    P=0.527N        |
|LOGISTIC REGRESSION|                                                        |                                    P=0.520N        |
|COCH-ARM / FISHERS |                                                        |                                    P=0.500N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Uterus                                                                                                                           |
|     Schwannoma Malignant                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                                                        |           3/100 (3%)               0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                                                        |           3.5%                     0.0%            |
|TERMINAL (d)       |                                                        |           1/59 (2%)                0/58 (0%)       |
|FIRST INCIDENCE    |                                                        |           462                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                                        |                                    P=0.132N        |
|POLY 3             |                                                        |                                    P=0.130N        |
|POLY 1.5           |                                                        |                                    P=0.128N        |
|POLY 6             |                                                        |                                    P=0.131N        |
|LOGISTIC REGRESSION|                                                        |                                    P=0.064N        |
|COCH-ARM / FISHERS |                                                        |                                    P=0.123N        |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 24
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|All Organs                                                                                                                       |
|     Leukemia: Lymphocytic, Monocytic, Mononuclear, or                                                                           |
|     Undifferentiated                                                                                                            |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  50/100 (50%)             36/100 (36%) |           20/100 (20%)             22/100 (22%)    |
|POLY-3 ADJUSTED (b)|                  53.1%                    39.7%        |           22.7%                    25.5%           |
|TERMINAL (d)       |                  24/57 (42%)              15/59 (25%)  |           11/59 (19%)              12/58 (21%)     |
|FIRST INCIDENCE    |                  303                      527          |           495                      526             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.063N     |                                    P=0.412         |
|POLY 3             |                                           P=0.045N*    |                                    P=0.398         |
|POLY 1.5           |                                           P=0.039N*    |                                    P=0.407         |
|POLY 6             |                                           P=0.049N*    |                                    P=0.401         |
|LOGISTIC REGRESSION|                                           P=0.028N*    |                                    P=0.414         |
|COCH-ARM / FISHERS |                                           P=0.032N*    |                                    P=0.431         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|All Organs                                                                                                                       |
|     Mesothelioma: Benign, Malignant, NOS                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  4/100 (4%)               4/100 (4%)   |           0/100 (0%)               0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                  4.6%                     4.7%         |           0.0%                     0.0%            |
|TERMINAL (d)       |                  2/57 (4%)                2/59 (3%)    |           0/59 (0%)                0/58 (0%)       |
|FIRST INCIDENCE    |                  658                      576          |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.631N     |                                    (e)             |
|POLY 3             |                                           P=0.632      |                                    (e)             |
|POLY 1.5           |                                           P=0.634      |                                    (e)             |
|POLY 6             |                                           P=0.632      |                                    (e)             |
|LOGISTIC REGRESSION|                                           P=0.632      |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.640N     |                                    (e)             |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 25
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|All Organs                                                                                                                       |
|     Mesothelioma: Malignant                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  4/100 (4%)               4/100 (4%)   |           0/100 (0%)               0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                  4.6%                     4.7%         |           0.0%                     0.0%            |
|TERMINAL (d)       |                  2/57 (4%)                2/59 (3%)    |           0/59 (0%)                0/58 (0%)       |
|FIRST INCIDENCE    |                  658                      576          |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.631N     |                                    (e)             |
|POLY 3             |                                           P=0.632      |                                    (e)             |
|POLY 1.5           |                                           P=0.634      |                                    (e)             |
|POLY 6             |                                           P=0.632      |                                    (e)             |
|LOGISTIC REGRESSION|                                           P=0.632      |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.640N     |                                    (e)             |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|All Organs                                                                                                                       |
|     Benign Tumors                                                                                                               |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  99/100 (99%)             94/100 (94%) |           92/100 (92%)             86/100 (86%)    |
|POLY-3 ADJUSTED (b)|                  99.8%                    96.7%        |           95.6%                    91.3%           |
|TERMINAL (d)       |                  57/57 (100%)             58/59 (98%)  |           58/59 (98%)              55/58 (95%)     |
|FIRST INCIDENCE    |                  303                      470          |           533                      430             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.290N     |                                    P=0.335N        |
|POLY 3             |                                           P=0.092N     |                                    P=0.145N        |
|POLY 1.5           |                                           P=0.070N     |                                    P=0.133N        |
|POLY 6             |                                           P=0.137N     |                                    P=0.176N        |
|LOGISTIC REGRESSION|                                           P=0.073N     |                                    P=0.251N        |
|COCH-ARM / FISHERS |                                           P=0.059N     |                                    P=0.129N        |
|=================================================================================================================================|
       Date:  01/28/98                           EXPERIMENT: 89029 TEST: 05                                            Page 26
                     Statistical Analysis of Primary Tumors in Rats(FISCHER 344)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 105 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|All Organs                                                                                                                       |
|     Malignant Tumors                                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  66/100 (66%)             58/100 (58%) |           40/100 (40%)             40/100 (40%)    |
|POLY-3 ADJUSTED (b)|                  68.1%                    60.7%        |           43.4%                    44.7%           |
|TERMINAL (d)       |                  32/57 (56%)              26/59 (44%)  |           22/59 (37%)              22/58 (38%)     |
|FIRST INCIDENCE    |                  303                      365          |           462                      480             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.229N     |                                    P=0.512         |
|POLY 3             |                                           P=0.173N     |                                    P=0.490         |
|POLY 1.5           |                                           P=0.169N     |                                    P=0.509         |
|POLY 6             |                                           P=0.171N     |                                    P=0.486         |
|LOGISTIC REGRESSION|                                           P=0.128N     |                                    P=0.557         |
|COCH-ARM / FISHERS |                                           P=0.154N     |                                    P=0.557N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|All Organs                                                                                                                       |
|     Malignant and Benign Tumors                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                  #                        #            |           #                        #               |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  100/100 (100%)           98/100 (98%) |           98/100 (98%)             94/100 (94%)    |
|POLY-3 ADJUSTED (b)|                  100.0%                   98.9%        |           99.1%                    96.5%           |
|TERMINAL (d)       |                  57/57 (100%)             58/59 (98%)  |           59/59 (100%)             56/58 (97%)     |
|FIRST INCIDENCE    |                  303                      365          |           462                      430             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.419N     |                                    P=0.440N        |
|POLY 3             |                                           P=0.471N     |                                    P=0.179N        |
|POLY 1.5           |                                           P=0.397N     |                                    P=0.160N        |
|POLY 6             |                                           P=0.498N     |                                    P=0.192N        |
|LOGISTIC REGRESSION|                                           P=0.267N     |                                    P=0.257N        |
|COCH-ARM / FISHERS |                                           P=0.249N     |                                    P=0.140N        |
|=================================================================================================================================|

(a)  Number of tumor-bearing animals /  number of animals examined at site.
(b)  Poly-3 adjusted lifetime tumor incidence.
(d)  Observed incidence at terminal kill.
(f)  Beneath the control incidence are the P-values associated with the trend 
test.  Beneath the dosed group incidence are the P-values corresponding to 
pairwise comparisons between the controls and that dosed group.  The life
table analysis regards tumors in animals dying prior to  terminal kill as
 being (directly or indirectly) the cause of death.
Logistic regression is an alternative
 method for analyzing the incidence of non-fatal tumors. The Cochran-Armitage
and Fishers exact tests compare directly the overall incidence rates
For all tests a negative trend is indicated by N
(e)  Value of Statistic cannot be computed.
(I)  Interim sacrifice
(T)  Terminal sacrifice
#   Tumor rates based on number of animals necropsied.
*   To the right of any statistical result, indicates significance at (P<=0.05).
**  To the right of any statistical result, indicates significance at (P<=0.01).