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TDMS Study 89029-06 Pathology Tables

NTP                                    STATISTICAL ANALYSIS OF NON-NEOPLASTIC LESIONS                          REPORT: PEIRPT10
LAB: I. I. T. Research Inst                               MAGNETIC FIELDS (EMF)                                DATE: 01/06/98

EXPERIMENT: 89029 TEST: 06                                                                                     TIME: 08:58:57
TEST TYPE:  CHRONIC                             CAGES FROM 0000 TO LAST CAGE                                   PAGE:
CONT: NO1-ES-25351                              ROUTE: MAGNETIC FIELDS                                         NTP C#: C89029
PATHOLOGIST: PLETCHER, J                                                                                       CAS: ELECTROMAG
NTP                                    STATISTICAL ANALYSIS OF NON-NEOPLASTIC LESIONS                          REPORT: PEIRPT10   
LAB: I. I. T. Research Inst                               MAGNETIC FIELDS (EMF)                                DATE: 01/06/98     
EXPERIMENT: 89029 TEST: 06                                                                                     TIME: 08:58:57     
TEST TYPE:  CHRONIC                             CAGES FROM 0000 TO LAST CAGE                                   PAGE:              
CONT: NO1-ES-25351                              ROUTE: MAGNETIC FIELDS                                         NTP C#: C89029     
PATHOLOGIST: PLETCHER, J                                                                                       CAS: ELECTROMAG    



SUMMARY OF STATISTICALLY SIGNIFICANT (P<=.05) RESULTS
IN THE ANALYSIS OF               MAGNETIC FIELDS (EMF)
===============================================================

Male Mice
------------
Organ                                 Morphology
-----                                 ----------
Adrenal Medulla                        Hyperplasia
Intestine Small, Ileum: Muscularis     Hypertrophy
Islets, Pancreatic                     Hyperplasia
Kidney: Cortex                         Infiltration Cellular Lymphocyte
Liver: Hepatocyte                      Vacuolization Cytoplasmic
Nose                                   Inflammation
Pancreas                               Vacuolization Cytoplasmic
Preputial Gland                        Atrophy
                                       Inflammation
Seminal Vesicle                        Cyst
Thymus                                 Atrophy
===============================================================
Female Mice
------------
Organ                                  Morphology
-----                                  ----------
Bone Marrow                            Myelofibrosis
Brain: Thalamus                        Mineralization
Clitoral Gland                         Cyst
Lymph Node, Mesenteric                 Hyperplasia Reticulum Cell
                                       Infiltration Cellular Histiocyte
Spleen                                 Hematopoietic Cell Proliferation
Stomach, Glandular: Epithelium         Atrophy
Thyroid Gland: Follicle                Cyst
===============================================================
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 1
                     Statistical Analysis of Non-neoplastic Lesions in        Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Adrenal Cortex                                                                                                                   |
|     Hematopoietic Cell Proliferation                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/99 (0%)                0/97 (0%)    |           0/92 (0%)                2/99 (2%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           0.0%                     2.2%            |
|TERMINAL (d)       |                  0/76 (0%)                0/73 (0%)    |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           ---                      607             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.237         |
|POLY 3             |                                           (e)          |                                    P=0.243         |
|POLY 1.5           |                                           (e)          |                                    P=0.244         |
|POLY 6             |                                           (e)          |                                    P=0.241         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.279         |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.267         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Adrenal Cortex: Capsule                                                                                                          |
|     Hyperplasia                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  86/99 (87%)              85/97 (88%)  |           91/92 (99%)              99/99 (100%)    |
|POLY-3 ADJUSTED (b)|                  88.5%                    90.4%        |           99.0%                    100.0%          |
|TERMINAL (d)       |                  69/76 (91%)              67/73 (92%)  |           70/70 (100%)             77/77 (100%)    |
|FIRST INCIDENCE    |                  386                      420          |           334                      309             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.418      |                                    P=0.498         |
|POLY 3             |                                           P=0.422      |                                    P=0.497         |
|POLY 1.5           |                                           P=0.455      |                                    P=0.484         |
|POLY 6             |                                           P=0.402      |                                    P=0.524         |
|LOGISTIC REGRESSION|                                           P=0.441      |                                    P=0.491         |
|COCH-ARM / FISHERS |                                           P=0.522      |                                    P=0.482         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 2
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Adrenal Cortex: Zona Fasciculata                                                                                                 |
|     Hyperplasia Focal                                                                                                           |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  4/99 (4%)                5/97 (5%)    |           0/92 (0%)                3/99 (3%)       |
|POLY-3 ADJUSTED (b)|                  4.3%                     5.7%         |           0.0%                     3.4%            |
|TERMINAL (d)       |                  3/76 (4%)                5/73 (7%)    |           0/70 (0%)                3/77 (4%)       |
|FIRST INCIDENCE    |                  717                      734 (T)      |           ---                      735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.475      |                                    P=0.140         |
|POLY 3             |                                           P=0.474      |                                    P=0.125         |
|POLY 1.5           |                                           P=0.479      |                                    P=0.127         |
|POLY 6             |                                           P=0.468      |                                    P=0.123         |
|LOGISTIC REGRESSION|                                           P=0.463      |                                    P=0.140         |
|COCH-ARM / FISHERS |                                           P=0.487      |                                    P=0.137         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Adrenal Cortex: Zona Fasciculata                                                                                                 |
|     Hypertrophy                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  9/99 (9%)                5/97 (5%)    |           0/92 (0%)                0/99 (0%)       |
|POLY-3 ADJUSTED (b)|                  9.8%                     5.7%         |           0.0%                     0.0%            |
|TERMINAL (d)       |                  9/76 (12%)               5/73 (7%)    |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  734 (T)                  734 (T)      |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.223N     |                                    (e)             |
|POLY 3             |                                           P=0.231N     |                                    (e)             |
|POLY 1.5           |                                           P=0.225N     |                                    (e)             |
|POLY 6             |                                           P=0.237N     |                                    (e)             |
|LOGISTIC REGRESSION|                                           P=0.223N     |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.215N     |                                    (e)             |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 3
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Adrenal Cortex: Zona Fasciculata                                                                                                 |
|     Hypertrophy Focal                                                                                                           |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  15/99 (15%)              19/97 (20%)  |           2/92 (2%)                0/99 (0%)       |
|POLY-3 ADJUSTED (b)|                  16.3%                    21.7%        |           2.3%                     0.0%            |
|TERMINAL (d)       |                  14/76 (18%)              18/73 (25%)  |           2/70 (3%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  683                      716          |           735 (T)                  ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.239      |                                    P=0.218N        |
|POLY 3             |                                           P=0.234      |                                    P=0.227N        |
|POLY 1.5           |                                           P=0.245      |                                    P=0.222N        |
|POLY 6             |                                           P=0.222      |                                    P=0.233N        |
|LOGISTIC REGRESSION|                                           P=0.219      |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.264      |                                    P=0.231N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Adrenal Cortex: Zona Fasciculata                                                                                                 |
|     Vacuolization Cytoplasmic                                                                                                   |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  2/99 (2%)                0/97 (0%)    |           0/92 (0%)                0/99 (0%)       |
|POLY-3 ADJUSTED (b)|                  2.2%                     0.0%         |           0.0%                     0.0%            |
|TERMINAL (d)       |                  2/76 (3%)                0/73 (0%)    |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  734 (T)                  ---          |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.248N     |                                    (e)             |
|POLY 3             |                                           P=0.255N     |                                    (e)             |
|POLY 1.5           |                                           P=0.251N     |                                    (e)             |
|POLY 6             |                                           P=0.258N     |                                    (e)             |
|LOGISTIC REGRESSION|                                           (e)          |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.254N     |                                    (e)             |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 4
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Adrenal Cortex: Zona Glomerulosa                                                                                                 |
|     Hyperplasia Focal                                                                                                           |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  3/99 (3%)                7/97 (7%)    |           0/92 (0%)                0/99 (0%)       |
|POLY-3 ADJUSTED (b)|                  3.2%                     7.9%         |           0.0%                     0.0%            |
|TERMINAL (d)       |                  1/76 (1%)                5/73 (7%)    |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  579                      553          |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.156      |                                    (e)             |
|POLY 3             |                                           P=0.148      |                                    (e)             |
|POLY 1.5           |                                           P=0.152      |                                    (e)             |
|POLY 6             |                                           P=0.144      |                                    (e)             |
|LOGISTIC REGRESSION|                                           P=0.164      |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.157      |                                    (e)             |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Adrenal Cortex: Zona Reticularis                                                                                                 |
|     Degeneration Fatty                                                                                                          |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  1/99 (1%)                0/97 (0%)    |           4/92 (4%)                3/99 (3%)       |
|POLY-3 ADJUSTED (b)|                  1.1%                     0.0%         |           4.6%                     3.4%            |
|TERMINAL (d)       |                  0/76 (0%)                0/73 (0%)    |           4/70 (6%)                3/77 (4%)       |
|FIRST INCIDENCE    |                  683                      ---          |           735 (T)                  735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.519N     |                                    P=0.449N        |
|POLY 3             |                                           P=0.520N     |                                    P=0.480N        |
|POLY 1.5           |                                           P=0.516N     |                                    P=0.470N        |
|POLY 6             |                                           P=0.525N     |                                    P=0.490N        |
|LOGISTIC REGRESSION|                                           P=0.494N     |                                    P=0.449N        |
|COCH-ARM / FISHERS |                                           P=0.505N     |                                    P=0.459N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 5
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Adrenal Medulla                                                                                                                  |
|     Hyperplasia                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/98 (0%)                5/96 (5%)    |           3/90 (3%)                3/98 (3%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     5.7%         |           3.5%                     3.4%            |
|TERMINAL (d)       |                  0/76 (0%)                5/73 (7%)    |           3/70 (4%)                3/76 (4%)       |
|FIRST INCIDENCE    |                  ---                      734 (T)      |           735 (T)                  735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.031 *    |                                    P=0.623N        |
|POLY 3             |                                           P=0.031 *    |                                    P=0.638N        |
|POLY 1.5           |                                           P=0.031 *    |                                    P=0.628N        |
|POLY 6             |                                           P=0.030 *    |                                    P=0.648N        |
|LOGISTIC REGRESSION|                                           P=0.031 *    |                                    P=0.623N        |
|COCH-ARM / FISHERS |                                           P=0.028 *    |                                    P=0.618N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Blood Vessel: Aorta                                                                                                              |
|     Mineralization                                                                                                              |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/97 (0%)                0/98 (0%)    |           2/98 (2%)                0/96 (0%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           2.2%                     0.0%            |
|TERMINAL (d)       |                  0/75 (0%)                0/72 (0%)    |           0/70 (0%)                0/75 (0%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           625                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.242N        |
|POLY 3             |                                           (e)          |                                    P=0.245N        |
|POLY 1.5           |                                           (e)          |                                    P=0.244N        |
|POLY 6             |                                           (e)          |                                    P=0.248N        |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.252N        |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.254N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 6
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Bone Marrow                                                                                                                      |
|     Atrophy                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/99 (0%)                3/100 (3%)   |           0/96 (0%)                1/100 (1%)      |
|POLY-3 ADJUSTED (b)|                  0.0%                     3.3%         |           0.0%                     1.1%            |
|TERMINAL (d)       |                  0/76 (0%)                2/74 (3%)    |           0/70 (0%)                1/77 (1%)       |
|FIRST INCIDENCE    |                  ---                      729          |           ---                      735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.119      |                                    P=0.519         |
|POLY 3             |                                           P=0.119      |                                    P=0.500         |
|POLY 1.5           |                                           P=0.121      |                                    P=0.500         |
|POLY 6             |                                           P=0.118      |                                    P=0.500         |
|LOGISTIC REGRESSION|                                           P=0.114      |                                    P=0.519         |
|COCH-ARM / FISHERS |                                           P=0.125      |                                    P=0.510         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Bone Marrow                                                                                                                      |
|     Hyperplasia                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  33/99 (33%)              25/100 (25%) |           23/96 (24%)              19/100 (19%)    |
|POLY-3 ADJUSTED (b)|                  34.9%                    26.7%        |           25.3%                    20.5%           |
|TERMINAL (d)       |                  23/76 (30%)              15/74 (20%)  |           12/70 (17%)              12/77 (16%)     |
|FIRST INCIDENCE    |                  497                      533          |           552                      567             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.189N     |                                    P=0.256N        |
|POLY 3             |                                           P=0.145N     |                                    P=0.271N        |
|POLY 1.5           |                                           P=0.138N     |                                    P=0.259N        |
|POLY 6             |                                           P=0.153N     |                                    P=0.289N        |
|LOGISTIC REGRESSION|                                           P=0.116N     |                                    P=0.248N        |
|COCH-ARM / FISHERS |                                           P=0.128N     |                                    P=0.251N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 7
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Bone Marrow                                                                                                                      |
|     Infiltration Cellular Focal Lymphocyte                                                                                      |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  3/99 (3%)                2/100 (2%)   |           0/96 (0%)                0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                  3.3%                     2.2%         |           0.0%                     0.0%            |
|TERMINAL (d)       |                  2/76 (3%)                2/74 (3%)    |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  715                      734 (T)      |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.515N     |                                    (e)             |
|POLY 3             |                                           P=0.511N     |                                    (e)             |
|POLY 1.5           |                                           P=0.505N     |                                    (e)             |
|POLY 6             |                                           P=0.519N     |                                    (e)             |
|LOGISTIC REGRESSION|                                           P=0.519N     |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.495N     |                                    (e)             |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Bone Marrow                                                                                                                      |
|     Myelofibrosis                                                                                                               |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/99 (0%)                2/100 (2%)   |           10/96 (10%)              21/100 (21%)    |
|POLY-3 ADJUSTED (b)|                  0.0%                     2.2%         |           11.3%                    23.0%           |
|TERMINAL (d)       |                  0/76 (0%)                2/74 (3%)    |           10/70 (14%)              18/77 (23%)     |
|FIRST INCIDENCE    |                  ---                      734 (T)      |           735 (T)                  576             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.233      |                                    P=0.043 *       |
|POLY 3             |                                           P=0.236      |                                    P=0.029 *       |
|POLY 1.5           |                                           P=0.238      |                                    P=0.031 *       |
|POLY 6             |                                           P=0.235      |                                    P=0.028 *       |
|LOGISTIC REGRESSION|                                           P=0.233      |                                    P=0.027 *       |
|COCH-ARM / FISHERS |                                           P=0.251      |                                    P=0.033 *       |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 8
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Bone Marrow: Myeloid Cell                                                                                                        |
|     Hyperplasia                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  2/99 (2%)                0/100 (0%)   |           3/96 (3%)                0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                  2.2%                     0.0%         |           3.4%                     0.0%            |
|TERMINAL (d)       |                  2/76 (3%)                0/74 (0%)    |           1/70 (1%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  734 (T)                  ---          |           666                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.245N     |                                    P=0.116N        |
|POLY 3             |                                           P=0.245N     |                                    P=0.116N        |
|POLY 1.5           |                                           P=0.241N     |                                    P=0.114N        |
|POLY 6             |                                           P=0.250N     |                                    P=0.120N        |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.116N        |
|COCH-ARM / FISHERS |                                           P=0.246N     |                                    P=0.116N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Brain: Thalamus                                                                                                                  |
|     Mineralization                                                                                                              |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  70/100 (70%)             63/100 (63%) |           47/99 (47%)              72/100 (72%)    |
|POLY-3 ADJUSTED (b)|                  71.8%                    65.6%        |           50.4%                    73.9%           |
|TERMINAL (d)       |                  55/76 (72%)              47/74 (64%)  |           35/70 (50%)              55/77 (71%)     |
|FIRST INCIDENCE    |                  386                      415          |           461                      449             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.306N     |                                    P=0.007 **      |
|POLY 3             |                                           P=0.215N     |                                    P<0.001 **      |
|POLY 1.5           |                                           P=0.203N     |                                    P<0.001 **      |
|POLY 6             |                                           P=0.226N     |                                    P<0.001 **      |
|LOGISTIC REGRESSION|                                           P=0.187N     |                                    P<0.001 **      |
|COCH-ARM / FISHERS |                                           P=0.184N     |                                    P<0.001 **      |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 9
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Clitoral Gland                                                                                                                   |
|     Atrophy                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                                                        |           80/89 (90%)              74/82 (90%)     |
|POLY-3 ADJUSTED (b)|                                                        |           92.1%                    90.7%           |
|TERMINAL (d)       |                                                        |           64/69 (93%)              63/69 (91%)     |
|FIRST INCIDENCE    |                                                        |           397                      309             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                                        |                                    P=0.207N        |
|POLY 3             |                                                        |                                    P=0.486N        |
|POLY 1.5           |                                                        |                                    P=0.527N        |
|POLY 6             |                                                        |                                    P=0.465N        |
|LOGISTIC REGRESSION|                                                        |                                    P=0.602         |
|COCH-ARM / FISHERS |                                                        |                                    P=0.571         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Clitoral Gland                                                                                                                   |
|     Cyst                                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                                                        |           84/89 (94%)              71/82 (87%)     |
|POLY-3 ADJUSTED (b)|                                                        |           96.0%                    89.1%           |
|TERMINAL (d)       |                                                        |           67/69 (97%)              64/69 (93%)     |
|FIRST INCIDENCE    |                                                        |           397                      534             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                                        |                                    P=0.015N*       |
|POLY 3             |                                                        |                                    P=0.069N        |
|POLY 1.5           |                                                        |                                    P=0.064N        |
|POLY 6             |                                                        |                                    P=0.081N        |
|LOGISTIC REGRESSION|                                                        |                                    P=0.041N*       |
|COCH-ARM / FISHERS |                                                        |                                    P=0.068N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 10
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Epididymis                                                                                                                       |
|     Granuloma Sperm                                                                                                             |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  2/98 (2%)                0/98 (0%)    |                                                    |
|POLY-3 ADJUSTED (b)|                  2.2%                     0.0%         |                                                    |
|TERMINAL (d)       |                  1/76 (1%)                0/73 (0%)    |                                                    |
|FIRST INCIDENCE    |                  684                      ---          |                                                    |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.254N     |                                                    |
|POLY 3             |                                           P=0.250N     |                                                    |
|POLY 1.5           |                                           P=0.245N     |                                                    |
|POLY 6             |                                           P=0.255N     |                                                    |
|LOGISTIC REGRESSION|                                           P=0.239N     |                                                    |
|COCH-ARM / FISHERS |                                           P=0.249N     |                                                    |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Epididymis                                                                                                                       |
|     Infiltration Cellular Lymphocyte                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  24/98 (24%)              24/98 (24%)  |                                                    |
|POLY-3 ADJUSTED (b)|                  26.1%                    26.9%        |                                                    |
|TERMINAL (d)       |                  21/76 (28%)              20/73 (27%)  |                                                    |
|FIRST INCIDENCE    |                  624                      605          |                                                    |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.498      |                                                    |
|POLY 3             |                                           P=0.522      |                                                    |
|POLY 1.5           |                                           P=0.539      |                                                    |
|POLY 6             |                                           P=0.504      |                                                    |
|LOGISTIC REGRESSION|                                           P=0.504      |                                                    |
|COCH-ARM / FISHERS |                                           P=0.566N     |                                                    |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 11
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Epididymis                                                                                                                       |
|     Inflammation                                                                                                                |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/98 (0%)                2/98 (2%)    |                                                    |
|POLY-3 ADJUSTED (b)|                  0.0%                     2.3%         |                                                    |
|TERMINAL (d)       |                  0/76 (0%)                2/73 (3%)    |                                                    |
|FIRST INCIDENCE    |                  ---                      734 (T)      |                                                    |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.230      |                                                    |
|POLY 3             |                                           P=0.235      |                                                    |
|POLY 1.5           |                                           P=0.236      |                                                    |
|POLY 6             |                                           P=0.234      |                                                    |
|LOGISTIC REGRESSION|                                           P=0.230      |                                                    |
|COCH-ARM / FISHERS |                                           P=0.249      |                                                    |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Epididymis                                                                                                                       |
|     Spermatocele                                                                                                                |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  2/98 (2%)                6/98 (6%)    |                                                    |
|POLY-3 ADJUSTED (b)|                  2.2%                     6.7%         |                                                    |
|TERMINAL (d)       |                  2/76 (3%)                5/73 (7%)    |                                                    |
|FIRST INCIDENCE    |                  734 (T)                  547          |                                                    |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.129      |                                                    |
|POLY 3             |                                           P=0.132      |                                                    |
|POLY 1.5           |                                           P=0.135      |                                                    |
|POLY 6             |                                           P=0.129      |                                                    |
|LOGISTIC REGRESSION|                                           P=0.137      |                                                    |
|COCH-ARM / FISHERS |                                           P=0.139      |                                                    |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 12
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Eye: Cornea                                                                                                                      |
|     Inflammation                                                                                                                |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/0 (0%)                 0/1 (0%)     |           2/2 (100%)               0/2 (0%)        |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           100.0%                   0.0%            |
|TERMINAL (d)       |                  0/0 (0%)                 0/1 (0%)     |           2/2 (100%)               0/0 (0%)        |
|FIRST INCIDENCE    |                  ---                      ---          |           735 (T)                  ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=1.000N        |
|POLY 3             |                                           (e)          |                                    P=1.000N        |
|POLY 1.5           |                                           (e)          |                                    P=0.887N        |
|POLY 6             |                                           (e)          |                                    P=1.000N        |
|LOGISTIC REGRESSION|                                           (e)          |                                    (e)             |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.167N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Gallbladder: Epithelium                                                                                                          |
|     Cyst                                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/84 (0%)                2/82 (2%)    |           5/70 (7%)                11/91 (12%)     |
|POLY-3 ADJUSTED (b)|                  0.0%                     2.5%         |           7.5%                     12.8%           |
|TERMINAL (d)       |                  0/69 (0%)                1/72 (1%)    |           4/62 (7%)                9/76 (12%)      |
|FIRST INCIDENCE    |                  ---                      686          |           725                      309             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.239      |                                    P=0.170         |
|POLY 3             |                                           P=0.239      |                                    P=0.200         |
|POLY 1.5           |                                           P=0.238      |                                    P=0.205         |
|POLY 6             |                                           P=0.240      |                                    P=0.192         |
|LOGISTIC REGRESSION|                                           P=0.225      |                                    P=0.234         |
|COCH-ARM / FISHERS |                                           P=0.242      |                                    P=0.221         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 13
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Harderian Gland                                                                                                                  |
|     Infiltration Cellular Lymphocyte                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  11/99 (11%)              14/99 (14%)  |           27/98 (28%)              36/97 (37%)     |
|POLY-3 ADJUSTED (b)|                  12.0%                    15.5%        |           30.2%                    40.3%           |
|TERMINAL (d)       |                  11/76 (15%)              12/74 (16%)  |           25/70 (36%)              33/77 (43%)     |
|FIRST INCIDENCE    |                  734 (T)                  581          |           551                      458             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.308      |                                    P=0.205         |
|POLY 3             |                                           P=0.314      |                                    P=0.102         |
|POLY 1.5           |                                           P=0.322      |                                    P=0.103         |
|POLY 6             |                                           P=0.308      |                                    P=0.101         |
|LOGISTIC REGRESSION|                                           P=0.296      |                                    P=0.097         |
|COCH-ARM / FISHERS |                                           P=0.335      |                                    P=0.101         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Heart                                                                                                                            |
|     Inflammation Focal                                                                                                          |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  2/100 (2%)               2/100 (2%)   |           0/98 (0%)                0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                  2.1%                     2.2%         |           0.0%                     0.0%            |
|TERMINAL (d)       |                  1/76 (1%)                0/74 (0%)    |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  386                      420          |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.686      |                                    (e)             |
|POLY 3             |                                           P=0.687      |                                    (e)             |
|POLY 1.5           |                                           P=0.689      |                                    (e)             |
|POLY 6             |                                           P=0.685      |                                    (e)             |
|LOGISTIC REGRESSION|                                           P=0.588N     |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.689N     |                                    (e)             |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 14
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Heart: Valve                                                                                                                     |
|     Thrombosis                                                                                                                  |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/100 (0%)               2/100 (2%)   |           0/98 (0%)                0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                  0.0%                     2.2%         |           0.0%                     0.0%            |
|TERMINAL (d)       |                  0/76 (0%)                0/74 (0%)    |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  ---                      420          |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.236      |                                    (e)             |
|POLY 3             |                                           P=0.237      |                                    (e)             |
|POLY 1.5           |                                           P=0.238      |                                    (e)             |
|POLY 6             |                                           P=0.237      |                                    (e)             |
|LOGISTIC REGRESSION|                                           P=0.293      |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.249      |                                    (e)             |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Intestine Large, Cecum: Lymphoid Tissue                                                                                          |
|     Hyperplasia                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  41/90 (46%)              46/85 (54%)  |           25/78 (32%)              32/92 (35%)     |
|POLY-3 ADJUSTED (b)|                  47.4%                    56.0%        |           32.7%                    36.2%           |
|TERMINAL (d)       |                  37/76 (49%)              42/73 (58%)  |           22/69 (32%)              26/77 (34%)     |
|FIRST INCIDENCE    |                  624                      547          |           397                      449             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.196      |                                    P=0.305         |
|POLY 3             |                                           P=0.169      |                                    P=0.373         |
|POLY 1.5           |                                           P=0.169      |                                    P=0.389         |
|POLY 6             |                                           P=0.165      |                                    P=0.354         |
|LOGISTIC REGRESSION|                                           P=0.154      |                                    P=0.450         |
|COCH-ARM / FISHERS |                                           P=0.163      |                                    P=0.416         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 15
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Intestine Small, Ileum                                                                                                           |
|     Inflammation                                                                                                                |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/91 (0%)                0/84 (0%)    |           1/78 (1%)                2/93 (2%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           1.3%                     2.3%            |
|TERMINAL (d)       |                  0/76 (0%)                0/72 (0%)    |           1/69 (1%)                2/77 (3%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           735 (T)                  735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.538         |
|POLY 3             |                                           (e)          |                                    P=0.533         |
|POLY 1.5           |                                           (e)          |                                    P=0.536         |
|POLY 6             |                                           (e)          |                                    P=0.528         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.538         |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.566         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Intestine Small, Ileum: Muscularis                                                                                               |
|     Hypertrophy                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/91 (0%)                7/84 (8%)    |           17/78 (22%)              15/93 (16%)     |
|POLY-3 ADJUSTED (b)|                  0.0%                     8.6%         |           22.8%                    17.2%           |
|TERMINAL (d)       |                  0/76 (0%)                4/72 (6%)    |           16/69 (23%)              12/77 (16%)     |
|FIRST INCIDENCE    |                  ---                      533          |           608                      458             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.010 *    |                                    P=0.312N        |
|POLY 3             |                                           P=0.008 **   |                                    P=0.242N        |
|POLY 1.5           |                                           P=0.007 **   |                                    P=0.232N        |
|POLY 6             |                                           P=0.008 **   |                                    P=0.257N        |
|LOGISTIC REGRESSION|                                           P=0.004 **   |                                    P=0.235N        |
|COCH-ARM / FISHERS |                                           P=0.005 **   |                                    P=0.227N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 16
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Intestine Small, Ileum: Peyer's Patch                                                                                            |
|     Hyperplasia                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/91 (0%)                0/84 (0%)    |           4/78 (5%)                5/93 (5%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           5.3%                     5.8%            |
|TERMINAL (d)       |                  0/76 (0%)                0/72 (0%)    |           3/69 (4%)                5/77 (7%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           334                      735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.559         |
|POLY 3             |                                           (e)          |                                    P=0.571         |
|POLY 1.5           |                                           (e)          |                                    P=0.581         |
|POLY 6             |                                           (e)          |                                    P=0.560         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.623         |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.609         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Intestine Small, Jejunum: Muscularis                                                                                             |
|     Hypertrophy                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/89 (0%)                2/85 (2%)    |           6/79 (8%)                7/92 (8%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     2.5%         |           7.9%                     8.1%            |
|TERMINAL (d)       |                  0/76 (0%)                1/73 (1%)    |           6/69 (9%)                6/77 (8%)       |
|FIRST INCIDENCE    |                  ---                      579          |           735 (T)                  704             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.233      |                                    P=0.575         |
|POLY 3             |                                           P=0.233      |                                    P=0.587         |
|POLY 1.5           |                                           P=0.233      |                                    P=0.595         |
|POLY 6             |                                           P=0.232      |                                    P=0.577         |
|LOGISTIC REGRESSION|                                           P=0.207      |                                    P=0.572         |
|COCH-ARM / FISHERS |                                           P=0.237      |                                    P=0.612N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 17
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Intestine Small, Jejunum: Peyer's Patch                                                                                          |
|     Hyperplasia                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  1/89 (1%)                1/85 (1%)    |           3/79 (4%)                7/92 (8%)       |
|POLY-3 ADJUSTED (b)|                  1.2%                     1.2%         |           4.0%                     8.1%            |
|TERMINAL (d)       |                  1/76 (1%)                1/73 (1%)    |           3/69 (4%)                7/77 (9%)       |
|FIRST INCIDENCE    |                  734 (T)                  734 (T)      |           735 (T)                  735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.752      |                                    P=0.211         |
|POLY 3             |                                           P=0.754      |                                    P=0.213         |
|POLY 1.5           |                                           P=0.755      |                                    P=0.219         |
|POLY 6             |                                           P=0.753      |                                    P=0.206         |
|LOGISTIC REGRESSION|                                           P=0.752      |                                    P=0.211         |
|COCH-ARM / FISHERS |                                           P=0.740      |                                    P=0.234         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Islets, Pancreatic                                                                                                               |
|     Hyperplasia                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  97/99 (98%)              89/98 (91%)  |           40/87 (46%)              47/94 (50%)     |
|POLY-3 ADJUSTED (b)|                  98.2%                    93.3%        |           47.7%                    50.9%           |
|TERMINAL (d)       |                  75/76 (99%)              70/74 (95%)  |           35/70 (50%)              36/76 (47%)     |
|FIRST INCIDENCE    |                  386                      415          |           334                      309             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.264N     |                                    P=0.333         |
|POLY 3             |                                           P=0.076N     |                                    P=0.390         |
|POLY 1.5           |                                           P=0.051N     |                                    P=0.376         |
|POLY 6             |                                           P=0.114N     |                                    P=0.398         |
|LOGISTIC REGRESSION|                                           P=0.040N*    |                                    P=0.366         |
|COCH-ARM / FISHERS |                                           P=0.028N*    |                                    P=0.347         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 18
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Kidney: Cortex                                                                                                                   |
|     Congestion                                                                                                                  |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  2/99 (2%)                0/97 (0%)    |           0/92 (0%)                0/99 (0%)       |
|POLY-3 ADJUSTED (b)|                  2.2%                     0.0%         |           0.0%                     0.0%            |
|TERMINAL (d)       |                  2/76 (3%)                0/73 (0%)    |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  734 (T)                  ---          |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.248N     |                                    (e)             |
|POLY 3             |                                           P=0.256N     |                                    (e)             |
|POLY 1.5           |                                           P=0.252N     |                                    (e)             |
|POLY 6             |                                           P=0.261N     |                                    (e)             |
|LOGISTIC REGRESSION|                                           (e)          |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.254N     |                                    (e)             |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Kidney: Cortex                                                                                                                   |
|     Cyst                                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  23/99 (23%)              22/97 (23%)  |           0/92 (0%)                0/99 (0%)       |
|POLY-3 ADJUSTED (b)|                  24.7%                    25.0%        |           0.0%                     0.0%            |
|TERMINAL (d)       |                  19/76 (25%)              20/73 (27%)  |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  579                      579          |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.563N     |                                    (e)             |
|POLY 3             |                                           P=0.553      |                                    (e)             |
|POLY 1.5           |                                           P=0.565N     |                                    (e)             |
|POLY 6             |                                           P=0.528      |                                    (e)             |
|LOGISTIC REGRESSION|                                           P=0.547      |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.531N     |                                    (e)             |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 19
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Kidney: Cortex                                                                                                                   |
|     Infiltration Cellular Lymphocyte                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  19/99 (19%)              37/97 (38%)  |           24/92 (26%)              16/99 (16%)     |
|POLY-3 ADJUSTED (b)|                  20.4%                    41.6%        |           27.5%                    17.7%           |
|TERMINAL (d)       |                  16/76 (21%)              32/73 (44%)  |           20/70 (29%)              14/77 (18%)     |
|FIRST INCIDENCE    |                  579                      553          |           542                      650             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.002 **   |                                    P=0.066N        |
|POLY 3             |                                           P<0.001 **   |                                    P=0.080N        |
|POLY 1.5           |                                           P=0.002 **   |                                    P=0.073N        |
|POLY 6             |                                           P<0.001 **   |                                    P=0.090N        |
|LOGISTIC REGRESSION|                                           P=0.002 **   |                                    P=0.079N        |
|COCH-ARM / FISHERS |                                           P=0.003 **   |                                    P=0.066N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Kidney: Cortex                                                                                                                   |
|     Metaplasia Focal Osseous                                                                                                    |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  4/99 (4%)                4/97 (4%)    |           4/92 (4%)                3/99 (3%)       |
|POLY-3 ADJUSTED (b)|                  4.3%                     4.6%         |           4.6%                     3.3%            |
|TERMINAL (d)       |                  3/76 (4%)                4/73 (6%)    |           1/70 (1%)                3/77 (4%)       |
|FIRST INCIDENCE    |                  666                      734 (T)      |           397                      735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.619      |                                    P=0.467N        |
|POLY 3             |                                           P=0.614      |                                    P=0.481N        |
|POLY 1.5           |                                           P=0.621      |                                    P=0.470N        |
|POLY 6             |                                           P=0.607      |                                    P=0.493N        |
|LOGISTIC REGRESSION|                                           P=0.606      |                                    P=0.439N        |
|COCH-ARM / FISHERS |                                           P=0.628      |                                    P=0.459N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 20
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Kidney: Cortex                                                                                                                   |
|     Mineralization                                                                                                              |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  79/99 (80%)              77/97 (79%)  |           1/92 (1%)                0/99 (0%)       |
|POLY-3 ADJUSTED (b)|                  83.6%                    83.8%        |           1.2%                     0.0%            |
|TERMINAL (d)       |                  66/76 (87%)              63/73 (86%)  |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  579                      505          |           625                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.489      |                                    P=0.502N        |
|POLY 3             |                                           P=0.568      |                                    P=0.483N        |
|POLY 1.5           |                                           P=0.579      |                                    P=0.478N        |
|POLY 6             |                                           P=0.561      |                                    P=0.490N        |
|LOGISTIC REGRESSION|                                           P=0.409      |                                    P=0.474N        |
|COCH-ARM / FISHERS |                                           P=0.542N     |                                    P=0.482N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Kidney: Cortex, Renal Tubule                                                                                                     |
|     Accumulation, Hyaline Droplet                                                                                               |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/99 (0%)                0/97 (0%)    |           0/92 (0%)                3/99 (3%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           0.0%                     3.3%            |
|TERMINAL (d)       |                  0/76 (0%)                0/73 (0%)    |           0/70 (0%)                1/77 (1%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           ---                      567             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.132         |
|POLY 3             |                                           (e)          |                                    P=0.128         |
|POLY 1.5           |                                           (e)          |                                    P=0.129         |
|POLY 6             |                                           (e)          |                                    P=0.127         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.143         |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.137         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 21
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Kidney: Cortex, Renal Tubule                                                                                                     |
|     Degeneration                                                                                                                |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  72/99 (73%)              71/97 (73%)  |           4/99 (4%)                1/97 (1%)       |
|POLY-3 ADJUSTED (b)|                  77.0%                    77.5%        |           4.4%                     1.1%            |
|TERMINAL (d)       |                  62/76 (82%)              59/73 (81%)  |           4/76 (5%)                1/73 (1%)       |
|FIRST INCIDENCE    |                  603                      533          |           734 (T)                  734 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.446      |                                    P=0.195N        |
|POLY 3             |                                           P=0.539      |                                    P=0.202N        |
|POLY 1.5           |                                           P=0.533      |                                    P=0.197N        |
|POLY 6             |                                           P=0.557      |                                    P=0.207N        |
|LOGISTIC REGRESSION|                                           P=0.363      |                                    P=0.195N        |
|COCH-ARM / FISHERS |                                           P=0.535      |                                    P=0.191N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Kidney: Cortex, Renal Tubule                                                                                                     |
|     Dilatation                                                                                                                  |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  2/99 (2%)                2/97 (2%)    |           1/92 (1%)                1/99 (1%)       |
|POLY-3 ADJUSTED (b)|                  2.2%                     2.3%         |           1.2%                     1.1%            |
|TERMINAL (d)       |                  0/76 (0%)                0/73 (0%)    |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  520                      505          |           608                      623             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.680      |                                    P=0.759         |
|POLY 3             |                                           P=0.679      |                                    P=0.745N        |
|POLY 1.5           |                                           P=0.682      |                                    P=0.741N        |
|POLY 6             |                                           P=0.675      |                                    P=0.750N        |
|LOGISTIC REGRESSION|                                           P=0.619N     |                                    P=0.734N        |
|COCH-ARM / FISHERS |                                           P=0.682      |                                    P=0.733N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 22
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Kidney: Cortex, Renal Tubule                                                                                                     |
|     Vacuolization Cytoplasmic                                                                                                   |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/99 (0%)                0/97 (0%)    |           0/92 (0%)                2/99 (2%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           0.0%                     2.2%            |
|TERMINAL (d)       |                  0/76 (0%)                0/73 (0%)    |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           ---                      580             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.240         |
|POLY 3             |                                           (e)          |                                    P=0.244         |
|POLY 1.5           |                                           (e)          |                                    P=0.245         |
|POLY 6             |                                           (e)          |                                    P=0.243         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.265         |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.267         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Kidney: Medulla                                                                                                                  |
|     Infiltration Cellular Lymphocyte                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  54/99 (55%)              47/97 (48%)  |           47/92 (51%)              57/99 (58%)     |
|POLY-3 ADJUSTED (b)|                  57.2%                    53.4%        |           52.8%                    61.9%           |
|TERMINAL (d)       |                  44/76 (58%)              45/73 (62%)  |           41/70 (59%)              53/77 (69%)     |
|FIRST INCIDENCE    |                  520                      553          |           334                      458             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.287N     |                                    P=0.246         |
|POLY 3             |                                           P=0.353N     |                                    P=0.132         |
|POLY 1.5           |                                           P=0.302N     |                                    P=0.164         |
|POLY 6             |                                           P=0.425N     |                                    P=0.100         |
|LOGISTIC REGRESSION|                                           P=0.337N     |                                    P=0.191         |
|COCH-ARM / FISHERS |                                           P=0.239N     |                                    P=0.225         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 23
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Kidney: Medulla                                                                                                                  |
|     Mineralization                                                                                                              |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  1/99 (1%)                2/97 (2%)    |           3/92 (3%)                1/99 (1%)       |
|POLY-3 ADJUSTED (b)|                  1.1%                     2.3%         |           3.5%                     1.1%            |
|TERMINAL (d)       |                  0/76 (0%)                0/73 (0%)    |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  666                      582          |           625                      534             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.490      |                                    P=0.301N        |
|POLY 3             |                                           P=0.489      |                                    P=0.286N        |
|POLY 1.5           |                                           P=0.492      |                                    P=0.281N        |
|POLY 6             |                                           P=0.487      |                                    P=0.293N        |
|LOGISTIC REGRESSION|                                           P=0.547      |                                    P=0.262N        |
|COCH-ARM / FISHERS |                                           P=0.492      |                                    P=0.283N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Kidney: Pelvis                                                                                                                   |
|     Calculus Micro Observation Only                                                                                             |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/99 (0%)                0/97 (0%)    |           3/92 (3%)                2/99 (2%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           3.5%                     2.2%            |
|TERMINAL (d)       |                  0/76 (0%)                0/73 (0%)    |           3/70 (4%)                2/77 (3%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           735 (T)                  735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.457N        |
|POLY 3             |                                           (e)          |                                    P=0.475N        |
|POLY 1.5           |                                           (e)          |                                    P=0.469N        |
|POLY 6             |                                           (e)          |                                    P=0.483N        |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.457N        |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.465N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 24
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Liver                                                                                                                            |
|     Angiectasis                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/100 (0%)               0/99 (0%)    |           1/98 (1%)                3/100 (3%)      |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           1.1%                     3.3%            |
|TERMINAL (d)       |                  0/76 (0%)                0/74 (0%)    |           1/70 (1%)                3/77 (4%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           735 (T)                  735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.341         |
|POLY 3             |                                           (e)          |                                    P=0.310         |
|POLY 1.5           |                                           (e)          |                                    P=0.312         |
|POLY 6             |                                           (e)          |                                    P=0.307         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.341         |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.318         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Liver                                                                                                                            |
|     Basophilic Focus                                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/100 (0%)               2/99 (2%)    |           2/98 (2%)                1/100 (1%)      |
|POLY-3 ADJUSTED (b)|                  0.0%                     2.2%         |           2.2%                     1.1%            |
|TERMINAL (d)       |                  0/76 (0%)                2/74 (3%)    |           2/70 (3%)                1/77 (1%)       |
|FIRST INCIDENCE    |                  ---                      734 (T)      |           735 (T)                  735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.233      |                                    P=0.467N        |
|POLY 3             |                                           P=0.235      |                                    P=0.495N        |
|POLY 1.5           |                                           P=0.236      |                                    P=0.492N        |
|POLY 6             |                                           P=0.234      |                                    P=0.500N        |
|LOGISTIC REGRESSION|                                           P=0.233      |                                    P=0.467N        |
|COCH-ARM / FISHERS |                                           P=0.246      |                                    P=0.492N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 25
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Liver                                                                                                                            |
|     Clear Cell Focus                                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  14/100 (14%)             14/99 (14%)  |           4/98 (4%)                5/100 (5%)      |
|POLY-3 ADJUSTED (b)|                  15.0%                    15.6%        |           4.5%                     5.5%            |
|TERMINAL (d)       |                  13/76 (17%)              13/74 (18%)  |           3/70 (4%)                3/77 (4%)       |
|FIRST INCIDENCE    |                  520                      582          |           608                      567             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.551      |                                    P=0.540         |
|POLY 3             |                                           P=0.543      |                                    P=0.507         |
|POLY 1.5           |                                           P=0.553      |                                    P=0.510         |
|POLY 6             |                                           P=0.534      |                                    P=0.503         |
|LOGISTIC REGRESSION|                                           P=0.542      |                                    P=0.512         |
|COCH-ARM / FISHERS |                                           P=0.569      |                                    P=0.513         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Liver                                                                                                                            |
|     Eosinophilic Focus                                                                                                          |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  12/100 (12%)             16/99 (16%)  |           6/98 (6%)                9/100 (9%)      |
|POLY-3 ADJUSTED (b)|                  12.9%                    17.7%        |           6.6%                     10.0%           |
|TERMINAL (d)       |                  10/76 (13%)              14/74 (19%)  |           5/70 (7%)                9/77 (12%)      |
|FIRST INCIDENCE    |                  520                      505          |           397                      735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.247      |                                    P=0.360         |
|POLY 3             |                                           P=0.243      |                                    P=0.296         |
|POLY 1.5           |                                           P=0.250      |                                    P=0.303         |
|POLY 6             |                                           P=0.236      |                                    P=0.288         |
|LOGISTIC REGRESSION|                                           P=0.250      |                                    P=0.308         |
|COCH-ARM / FISHERS |                                           P=0.261      |                                    P=0.311         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 26
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Liver                                                                                                                            |
|     Infiltration Cellular Focal Mixed Cell                                                                                      |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  6/100 (6%)               11/99 (11%)  |           53/98 (54%)              51/100 (51%)    |
|POLY-3 ADJUSTED (b)|                  6.5%                     12.3%        |           58.9%                    55.2%           |
|TERMINAL (d)       |                  6/76 (8%)                11/74 (15%)  |           47/70 (67%)              46/77 (60%)     |
|FIRST INCIDENCE    |                  734 (T)                  734 (T)      |           666                      534             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.139      |                                    P=0.210N        |
|POLY 3             |                                           P=0.138      |                                    P=0.362N        |
|POLY 1.5           |                                           P=0.143      |                                    P=0.363N        |
|POLY 6             |                                           P=0.134      |                                    P=0.369N        |
|LOGISTIC REGRESSION|                                           P=0.139      |                                    P=0.447N        |
|COCH-ARM / FISHERS |                                           P=0.150      |                                    P=0.385N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Liver                                                                                                                            |
|     Mixed Cell Focus                                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  4/100 (4%)               3/99 (3%)    |           0/98 (0%)                0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                  4.3%                     3.4%         |           0.0%                     0.0%            |
|TERMINAL (d)       |                  4/76 (5%)                3/74 (4%)    |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  734 (T)                  734 (T)      |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.514N     |                                    (e)             |
|POLY 3             |                                           P=0.521N     |                                    (e)             |
|POLY 1.5           |                                           P=0.515N     |                                    (e)             |
|POLY 6             |                                           P=0.526N     |                                    (e)             |
|LOGISTIC REGRESSION|                                           P=0.514N     |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.506N     |                                    (e)             |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 27
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Liver                                                                                                                            |
|     Necrosis                                                                                                                    |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  7/100 (7%)               3/99 (3%)    |           4/98 (4%)                5/100 (5%)      |
|POLY-3 ADJUSTED (b)|                  7.4%                     3.3%         |           4.4%                     5.4%            |
|TERMINAL (d)       |                  1/76 (1%)                1/74 (1%)    |           0/70 (0%)                2/77 (3%)       |
|FIRST INCIDENCE    |                  520                      582          |           432                      309             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.187N     |                                    P=0.508         |
|POLY 3             |                                           P=0.187N     |                                    P=0.508         |
|POLY 1.5           |                                           P=0.180N     |                                    P=0.511         |
|POLY 6             |                                           P=0.195N     |                                    P=0.501         |
|LOGISTIC REGRESSION|                                           P=0.115N     |                                    P=0.459         |
|COCH-ARM / FISHERS |                                           P=0.170N     |                                    P=0.513         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Liver: Hepatocyte                                                                                                                |
|     Vacuolization Cytoplasmic                                                                                                   |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  13/100 (13%)             5/99 (5%)    |           14/98 (14%)              14/100 (14%)    |
|POLY-3 ADJUSTED (b)|                  13.7%                    5.5%         |           14.9%                    15.2%           |
|TERMINAL (d)       |                  8/76 (11%)               2/74 (3%)    |           6/70 (9%)                10/77 (13%)     |
|FIRST INCIDENCE    |                  386                      415          |           288                      534             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.052N     |                                    P=0.518N        |
|POLY 3             |                                           P=0.050N     |                                    P=0.563         |
|POLY 1.5           |                                           P=0.048N*    |                                    P=0.578         |
|POLY 6             |                                           P=0.053N     |                                    P=0.547         |
|LOGISTIC REGRESSION|                                           P=0.020N*    |                                    P=0.572N        |
|COCH-ARM / FISHERS |                                           P=0.043N*    |                                    P=0.558N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 28
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lung                                                                                                                             |
|     Infiltration Cellular Lymphocyte                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  20/100 (20%)             16/99 (16%)  |           32/95 (34%)              30/100 (30%)    |
|POLY-3 ADJUSTED (b)|                  21.5%                    17.8%        |           36.5%                    32.1%           |
|TERMINAL (d)       |                  19/76 (25%)              15/74 (20%)  |           30/70 (43%)              23/77 (30%)     |
|FIRST INCIDENCE    |                  497                      620          |           667                      458             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.318N     |                                    P=0.296N        |
|POLY 3             |                                           P=0.333N     |                                    P=0.318N        |
|POLY 1.5           |                                           P=0.321N     |                                    P=0.326N        |
|POLY 6             |                                           P=0.342N     |                                    P=0.314N        |
|LOGISTIC REGRESSION|                                           P=0.335N     |                                    P=0.363N        |
|COCH-ARM / FISHERS |                                           P=0.302N     |                                    P=0.345N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lung: Alveolar Epithelium                                                                                                        |
|     Hyperplasia Focal                                                                                                           |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  2/100 (2%)               2/99 (2%)    |           4/95 (4%)                1/100 (1%)      |
|POLY-3 ADJUSTED (b)|                  2.2%                     2.2%         |           4.5%                     1.1%            |
|TERMINAL (d)       |                  2/76 (3%)                2/74 (3%)    |           3/70 (4%)                1/77 (1%)       |
|FIRST INCIDENCE    |                  734 (T)                  734 (T)      |           432                      735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.684      |                                    P=0.160N        |
|POLY 3             |                                           P=0.684      |                                    P=0.173N        |
|POLY 1.5           |                                           P=0.686      |                                    P=0.169N        |
|POLY 6             |                                           P=0.682      |                                    P=0.178N        |
|LOGISTIC REGRESSION|                                           P=0.684      |                                    P=0.163N        |
|COCH-ARM / FISHERS |                                           P=0.686      |                                    P=0.169N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 29
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lung: Alveolus                                                                                                                   |
|     Infiltration Cellular Histiocyte                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  3/100 (3%)               9/99 (9%)    |           1/95 (1%)                0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                  3.2%                     10.0%        |           1.1%                     0.0%            |
|TERMINAL (d)       |                  2/76 (3%)                8/74 (11%)   |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  715                      668          |           723                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.062      |                                    P=0.500N        |
|POLY 3             |                                           P=0.060      |                                    P=0.486N        |
|POLY 1.5           |                                           P=0.062      |                                    P=0.483N        |
|POLY 6             |                                           P=0.058      |                                    P=0.491N        |
|LOGISTIC REGRESSION|                                           P=0.058      |                                    P=0.494N        |
|COCH-ARM / FISHERS |                                           P=0.065      |                                    P=0.487N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lung: Artery                                                                                                                     |
|     Mineralization                                                                                                              |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/100 (0%)               0/99 (0%)    |           2/95 (2%)                0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           2.3%                     0.0%            |
|TERMINAL (d)       |                  0/76 (0%)                0/74 (0%)    |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           625                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.241N        |
|POLY 3             |                                           (e)          |                                    P=0.229N        |
|POLY 1.5           |                                           (e)          |                                    P=0.225N        |
|POLY 6             |                                           (e)          |                                    P=0.234N        |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.224N        |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.236N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 30
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node, Mandibular                                                                                                           |
|     Atrophy                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  4/92 (4%)                1/90 (1%)    |           3/84 (4%)                3/92 (3%)       |
|POLY-3 ADJUSTED (b)|                  4.6%                     1.2%         |           3.8%                     3.6%            |
|TERMINAL (d)       |                  1/72 (1%)                1/69 (1%)    |           0/66 (0%)                2/70 (3%)       |
|FIRST INCIDENCE    |                  582                      734 (T)      |           707                      656             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.196N     |                                    P=0.643N        |
|POLY 3             |                                           P=0.205N     |                                    P=0.630N        |
|POLY 1.5           |                                           P=0.199N     |                                    P=0.622N        |
|POLY 6             |                                           P=0.212N     |                                    P=0.641N        |
|LOGISTIC REGRESSION|                                           P=0.170N     |                                    P=0.627N        |
|COCH-ARM / FISHERS |                                           P=0.191N     |                                    P=0.615N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node, Mandibular                                                                                                           |
|     Hemorrhage                                                                                                                  |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/92 (0%)                1/90 (1%)    |           2/84 (2%)                3/92 (3%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     1.2%         |           2.6%                     3.6%            |
|TERMINAL (d)       |                  0/72 (0%)                1/69 (1%)    |           2/66 (3%)                1/70 (1%)       |
|FIRST INCIDENCE    |                  ---                      734 (T)      |           735 (T)                  650             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.492      |                                    P=0.514         |
|POLY 3             |                                           P=0.500      |                                    P=0.522         |
|POLY 1.5           |                                           P=0.500      |                                    P=0.527         |
|POLY 6             |                                           P=0.500      |                                    P=0.517         |
|LOGISTIC REGRESSION|                                           P=0.492      |                                    P=0.545         |
|COCH-ARM / FISHERS |                                           P=0.495      |                                    P=0.543         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 31
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node, Mandibular                                                                                                           |
|     Hyperplasia                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  1/92 (1%)                3/90 (3%)    |           8/84 (10%)               4/92 (4%)       |
|POLY-3 ADJUSTED (b)|                  1.2%                     3.7%         |           10.2%                    4.8%            |
|TERMINAL (d)       |                  1/72 (1%)                3/69 (4%)    |           8/66 (12%)               4/70 (6%)       |
|FIRST INCIDENCE    |                  734 (T)                  734 (T)      |           735 (T)                  735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.292      |                                    P=0.156N        |
|POLY 3             |                                           P=0.293      |                                    P=0.157N        |
|POLY 1.5           |                                           P=0.296      |                                    P=0.150N        |
|POLY 6             |                                           P=0.291      |                                    P=0.166N        |
|LOGISTIC REGRESSION|                                           P=0.292      |                                    P=0.156N        |
|COCH-ARM / FISHERS |                                           P=0.302      |                                    P=0.144N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node, Mandibular                                                                                                           |
|     Hyperplasia Reticulum Cell                                                                                                  |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/92 (0%)                0/90 (0%)    |           0/84 (0%)                2/92 (2%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           0.0%                     2.4%            |
|TERMINAL (d)       |                  0/72 (0%)                0/69 (0%)    |           0/66 (0%)                2/70 (3%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           ---                      735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.252         |
|POLY 3             |                                           (e)          |                                    P=0.244         |
|POLY 1.5           |                                           (e)          |                                    P=0.246         |
|POLY 6             |                                           (e)          |                                    P=0.242         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.252         |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.272         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 32
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node, Mandibular                                                                                                           |
|     Infiltration Cellular Histiocyte                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/92 (0%)                3/90 (3%)    |           0/84 (0%)                0/92 (0%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     3.6%         |           0.0%                     0.0%            |
|TERMINAL (d)       |                  0/72 (0%)                0/69 (0%)    |           0/66 (0%)                0/70 (0%)       |
|FIRST INCIDENCE    |                  ---                      547          |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.121      |                                    (e)             |
|POLY 3             |                                           P=0.118      |                                    (e)             |
|POLY 1.5           |                                           P=0.118      |                                    (e)             |
|POLY 6             |                                           P=0.118      |                                    (e)             |
|LOGISTIC REGRESSION|                                           P=0.161      |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.119      |                                    (e)             |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node, Mandibular                                                                                                           |
|     Infiltration Cellular Mixed Cell                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  4/92 (4%)                1/90 (1%)    |           2/84 (2%)                1/92 (1%)       |
|POLY-3 ADJUSTED (b)|                  4.7%                     1.2%         |           2.6%                     1.2%            |
|TERMINAL (d)       |                  2/72 (3%)                0/69 (0%)    |           2/66 (3%)                0/70 (0%)       |
|FIRST INCIDENCE    |                  705                      729          |           735 (T)                  650             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.198N     |                                    P=0.488N        |
|POLY 3             |                                           P=0.202N     |                                    P=0.473N        |
|POLY 1.5           |                                           P=0.197N     |                                    P=0.466N        |
|POLY 6             |                                           P=0.206N     |                                    P=0.481N        |
|LOGISTIC REGRESSION|                                           P=0.200N     |                                    P=0.468N        |
|COCH-ARM / FISHERS |                                           P=0.191N     |                                    P=0.466N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 33
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node, Mandibular                                                                                                           |
|     Infiltration Cellular Plasma Cell                                                                                           |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/92 (0%)                1/90 (1%)    |           2/84 (2%)                1/92 (1%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     1.2%         |           2.6%                     1.2%            |
|TERMINAL (d)       |                  0/72 (0%)                0/69 (0%)    |           2/66 (3%)                1/70 (1%)       |
|FIRST INCIDENCE    |                  ---                      581          |           735 (T)                  735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.496      |                                    P=0.480N        |
|POLY 3             |                                           P=0.500      |                                    P=0.475N        |
|POLY 1.5           |                                           P=0.500      |                                    P=0.467N        |
|POLY 6             |                                           P=0.500      |                                    P=0.484N        |
|LOGISTIC REGRESSION|                                           P=0.547      |                                    P=0.480N        |
|COCH-ARM / FISHERS |                                           P=0.495      |                                    P=0.466N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node, Mandibular                                                                                                           |
|     Pigmentation                                                                                                                |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  2/92 (2%)                4/90 (4%)    |           22/84 (26%)              18/92 (20%)     |
|POLY-3 ADJUSTED (b)|                  2.3%                     4.9%         |           27.9%                    21.7%           |
|TERMINAL (d)       |                  1/72 (1%)                2/69 (3%)    |           18/66 (27%)              17/70 (24%)     |
|FIRST INCIDENCE    |                  603                      666          |           667                      650             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.320      |                                    P=0.236N        |
|POLY 3             |                                           P=0.320      |                                    P=0.228N        |
|POLY 1.5           |                                           P=0.324      |                                    P=0.211N        |
|POLY 6             |                                           P=0.317      |                                    P=0.254N        |
|LOGISTIC REGRESSION|                                           P=0.347      |                                    P=0.259N        |
|COCH-ARM / FISHERS |                                           P=0.331      |                                    P=0.193N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 34
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node, Mesenteric                                                                                                           |
|     Atrophy                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  6/87 (7%)                12/92 (13%)  |           12/83 (14%)              22/95 (23%)     |
|POLY-3 ADJUSTED (b)|                  7.3%                     13.9%        |           15.0%                    25.1%           |
|TERMINAL (d)       |                  3/70 (4%)                8/72 (11%)   |           9/68 (13%)               17/74 (23%)     |
|FIRST INCIDENCE    |                  497                      553          |           667                      458             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.114      |                                    P=0.071         |
|POLY 3             |                                           P=0.122      |                                    P=0.075         |
|POLY 1.5           |                                           P=0.125      |                                    P=0.083         |
|POLY 6             |                                           P=0.119      |                                    P=0.066         |
|LOGISTIC REGRESSION|                                           P=0.144      |                                    P=0.088         |
|COCH-ARM / FISHERS |                                           P=0.132      |                                    P=0.099         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node, Mesenteric                                                                                                           |
|     Ectasia                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/87 (0%)                0/92 (0%)    |           3/83 (4%)                0/95 (0%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           3.8%                     0.0%            |
|TERMINAL (d)       |                  0/70 (0%)                0/72 (0%)    |           3/68 (4%)                0/74 (0%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           735 (T)                  ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.108N        |
|POLY 3             |                                           (e)          |                                    P=0.102N        |
|POLY 1.5           |                                           (e)          |                                    P=0.098N        |
|POLY 6             |                                           (e)          |                                    P=0.107N        |
|LOGISTIC REGRESSION|                                           (e)          |                                    (e)             |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.099N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 35
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node, Mesenteric                                                                                                           |
|     Hemorrhage                                                                                                                  |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  3/87 (3%)                5/92 (5%)    |           3/83 (4%)                2/95 (2%)       |
|POLY-3 ADJUSTED (b)|                  3.7%                     5.9%         |           3.8%                     2.3%            |
|TERMINAL (d)       |                  2/70 (3%)                5/72 (7%)    |           3/68 (4%)                1/74 (1%)       |
|FIRST INCIDENCE    |                  684                      734 (T)      |           735 (T)                  623             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.367      |                                    P=0.469N        |
|POLY 3             |                                           P=0.376      |                                    P=0.452N        |
|POLY 1.5           |                                           P=0.380      |                                    P=0.442N        |
|POLY 6             |                                           P=0.371      |                                    P=0.464N        |
|LOGISTIC REGRESSION|                                           P=0.375      |                                    P=0.440N        |
|COCH-ARM / FISHERS |                                           P=0.392      |                                    P=0.436N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node, Mesenteric                                                                                                           |
|     Hyperplasia                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/87 (0%)                3/92 (3%)    |           2/83 (2%)                2/95 (2%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     3.5%         |           2.5%                     2.3%            |
|TERMINAL (d)       |                  0/70 (0%)                3/72 (4%)    |           2/68 (3%)                2/74 (3%)       |
|FIRST INCIDENCE    |                  ---                      734 (T)      |           735 (T)                  735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.127      |                                    P=0.663N        |
|POLY 3             |                                           P=0.126      |                                    P=0.655N        |
|POLY 1.5           |                                           P=0.127      |                                    P=0.645N        |
|POLY 6             |                                           P=0.125      |                                    P=0.666N        |
|LOGISTIC REGRESSION|                                           P=0.127      |                                    P=0.663N        |
|COCH-ARM / FISHERS |                                           P=0.134      |                                    P=0.637N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 36
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node, Mesenteric                                                                                                           |
|     Hyperplasia Reticulum Cell                                                                                                  |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/87 (0%)                0/92 (0%)    |           3/83 (4%)                15/95 (16%)     |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           3.8%                     17.4%           |
|TERMINAL (d)       |                  0/70 (0%)                0/72 (0%)    |           3/68 (4%)                14/74 (19%)     |
|FIRST INCIDENCE    |                  ---                      ---          |           735 (T)                  656             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.005 **      |
|POLY 3             |                                           (e)          |                                    P=0.004 **      |
|POLY 1.5           |                                           (e)          |                                    P=0.005 **      |
|POLY 6             |                                           (e)          |                                    P=0.004 **      |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.004 **      |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.006 **      |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node, Mesenteric                                                                                                           |
|     Infiltration Cellular Histiocyte                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  59/87 (68%)              72/92 (78%)  |           50/83 (60%)              41/95 (43%)     |
|POLY-3 ADJUSTED (b)|                  70.4%                    81.4%        |           61.7%                    46.7%           |
|TERMINAL (d)       |                  50/70 (71%)              60/72 (83%)  |           44/68 (65%)              37/74 (50%)     |
|FIRST INCIDENCE    |                  520                      533          |           397                      458             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.055      |                                    P=0.044N*       |
|POLY 3             |                                           P=0.059      |                                    P=0.032N*       |
|POLY 1.5           |                                           P=0.065      |                                    P=0.024N*       |
|POLY 6             |                                           P=0.056      |                                    P=0.045N*       |
|LOGISTIC REGRESSION|                                           P=0.054      |                                    P=0.031N*       |
|COCH-ARM / FISHERS |                                           P=0.080      |                                    P=0.017N*       |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 37
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node, Mesenteric                                                                                                           |
|     Infiltration Cellular Mixed Cell                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  3/87 (3%)                6/92 (7%)    |           4/83 (5%)                5/95 (5%)       |
|POLY-3 ADJUSTED (b)|                  3.7%                     7.1%         |           5.0%                     5.8%            |
|TERMINAL (d)       |                  3/70 (4%)                5/72 (7%)    |           4/68 (6%)                5/74 (7%)       |
|FIRST INCIDENCE    |                  734 (T)                  716          |           735 (T)                  735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.258      |                                    P=0.552         |
|POLY 3             |                                           P=0.264      |                                    P=0.545         |
|POLY 1.5           |                                           P=0.267      |                                    P=0.556         |
|POLY 6             |                                           P=0.261      |                                    P=0.532         |
|LOGISTIC REGRESSION|                                           P=0.259      |                                    P=0.552         |
|COCH-ARM / FISHERS |                                           P=0.277      |                                    P=0.584         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node, Mesenteric                                                                                                           |
|     Infiltration Cellular Plasma Cell                                                                                           |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/87 (0%)                1/92 (1%)    |           5/83 (6%)                6/95 (6%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     1.2%         |           6.3%                     6.9%            |
|TERMINAL (d)       |                  0/70 (0%)                1/72 (1%)    |           5/68 (7%)                5/74 (7%)       |
|FIRST INCIDENCE    |                  ---                      734 (T)      |           735 (T)                  650             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.506      |                                    P=0.552         |
|POLY 3             |                                           P=0.500      |                                    P=0.553         |
|POLY 1.5           |                                           P=0.500      |                                    P=0.565         |
|POLY 6             |                                           P=0.500      |                                    P=0.540         |
|LOGISTIC REGRESSION|                                           P=0.506      |                                    P=0.547         |
|COCH-ARM / FISHERS |                                           P=0.514      |                                    P=0.593         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 38
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node: Lumbar                                                                                                               |
|     Ectasia                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/6 (0%)                 0/7 (0%)     |           3/19 (16%)               0/12 (0%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           16.8%                    0.0%            |
|TERMINAL (d)       |                  0/6 (0%)                 0/3 (0%)     |           3/11 (27%)               0/7 (0%)        |
|FIRST INCIDENCE    |                  ---                      ---          |           735 (T)                  ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.200N        |
|POLY 3             |                                           (e)          |                                    P=0.291N        |
|POLY 1.5           |                                           (e)          |                                    P=0.271N        |
|POLY 6             |                                           (e)          |                                    P=0.319N        |
|LOGISTIC REGRESSION|                                           (e)          |                                    (e)             |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.216N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Lymph Node: Lumbar                                                                                                               |
|     Hemorrhage                                                                                                                  |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  1/6 (17%)                0/7 (0%)     |           4/19 (21%)               0/12 (0%)       |
|POLY-3 ADJUSTED (b)|                  16.7%                    0.0%         |           22.3%                    0.0%            |
|TERMINAL (d)       |                  1/6 (17%)                0/3 (0%)     |           4/11 (36%)               0/7 (0%)        |
|FIRST INCIDENCE    |                  734 (T)                  ---          |           735 (T)                  ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.638N     |                                    P=0.116N        |
|POLY 3             |                                           P=0.534N     |                                    P=0.183N        |
|POLY 1.5           |                                           P=0.487N     |                                    P=0.167N        |
|POLY 6             |                                           P=0.617N     |                                    P=0.207N        |
|LOGISTIC REGRESSION|                                           (e)          |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.462N     |                                    P=0.123N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 39
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Mammary Gland                                                                                                                    |
|     Hyperplasia                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/2 (0%)                 0/1 (0%)     |           3/94 (3%)                3/98 (3%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           3.5%                     3.4%            |
|TERMINAL (d)       |                  0/1 (0%)                 0/1 (0%)     |           1/70 (1%)                2/76 (3%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           702                      656             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.644N        |
|POLY 3             |                                           (e)          |                                    P=0.647N        |
|POLY 1.5           |                                           (e)          |                                    P=0.641N        |
|POLY 6             |                                           (e)          |                                    P=0.655N        |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.644N        |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.639N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Mammary Gland: Duct                                                                                                              |
|     Dilatation                                                                                                                  |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/2 (0%)                 0/1 (0%)     |           10/94 (11%)              12/98 (12%)     |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           11.5%                    13.4%           |
|TERMINAL (d)       |                  0/1 (0%)                 0/1 (0%)     |           6/70 (9%)                9/76 (12%)      |
|FIRST INCIDENCE    |                  ---                      ---          |           542                      580             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.466         |
|POLY 3             |                                           (e)          |                                    P=0.436         |
|POLY 1.5           |                                           (e)          |                                    P=0.445         |
|POLY 6             |                                           (e)          |                                    P=0.424         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.449         |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.452         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 40
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Mesentery: Fat                                                                                                                   |
|     Inflammation                                                                                                                |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  1/13 (8%)                0/9 (0%)     |           6/36 (17%)               14/53 (26%)     |
|POLY-3 ADJUSTED (b)|                  8.1%                     0.0%         |           17.3%                    28.7%           |
|TERMINAL (d)       |                  1/10 (10%)               0/5 (0%)     |           4/24 (17%)               11/37 (30%)     |
|FIRST INCIDENCE    |                  734 (T)                  ---          |           701                      458             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.638N     |                                    P=0.172         |
|POLY 3             |                                           P=0.716N     |                                    P=0.160         |
|POLY 1.5           |                                           P=0.686N     |                                    P=0.173         |
|POLY 6             |                                           P=0.754N     |                                    P=0.144         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.201         |
|COCH-ARM / FISHERS |                                           P=0.591N     |                                    P=0.207         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Mesentery: Fat                                                                                                                   |
|     Necrosis                                                                                                                    |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  11/13 (85%)              7/9 (78%)    |           22/36 (61%)              31/53 (58%)     |
|POLY-3 ADJUSTED (b)|                  84.6%                    90.5%        |           62.5%                    62.4%           |
|TERMINAL (d)       |                  8/10 (80%)               5/5 (100%)   |           17/24 (71%)              24/37 (65%)     |
|FIRST INCIDENCE    |                  582                      667          |           603                      567             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.582      |                                    P=0.563         |
|POLY 3             |                                           P=0.689      |                                    P=0.574N        |
|POLY 1.5           |                                           P=0.768      |                                    P=0.533N        |
|POLY 6             |                                           P=0.586      |                                    P=0.535         |
|LOGISTIC REGRESSION|                                           P=0.617      |                                    P=0.568         |
|COCH-ARM / FISHERS |                                           P=0.550N     |                                    P=0.490N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 41
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Nose                                                                                                                             |
|     Inflammation                                                                                                                |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  1/99 (1%)                7/100 (7%)   |           0/99 (0%)                0/99 (0%)       |
|POLY-3 ADJUSTED (b)|                  1.1%                     7.7%         |           0.0%                     0.0%            |
|TERMINAL (d)       |                  1/76 (1%)                3/74 (4%)    |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  734 (T)                  605          |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.034 *    |                                    (e)             |
|POLY 3             |                                           P=0.033 *    |                                    (e)             |
|POLY 1.5           |                                           P=0.034 *    |                                    (e)             |
|POLY 6             |                                           P=0.032 *    |                                    (e)             |
|LOGISTIC REGRESSION|                                           P=0.037 *    |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.033 *    |                                    (e)             |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Ovary                                                                                                                            |
|     Angiectasis                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                                                        |           0/79 (0%)                3/96 (3%)       |
|POLY-3 ADJUSTED (b)|                                                        |           0.0%                     3.4%            |
|TERMINAL (d)       |                                                        |           0/65 (0%)                3/77 (4%)       |
|FIRST INCIDENCE    |                                                        |           ---                      735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                                        |                                    P=0.154         |
|POLY 3             |                                                        |                                    P=0.141         |
|POLY 1.5           |                                                        |                                    P=0.143         |
|POLY 6             |                                                        |                                    P=0.138         |
|LOGISTIC REGRESSION|                                                        |                                    P=0.154         |
|COCH-ARM / FISHERS |                                                        |                                    P=0.163         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 42
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Ovary                                                                                                                            |
|     Atrophy                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                                                        |           4/79 (5%)                3/96 (3%)       |
|POLY-3 ADJUSTED (b)|                                                        |           5.4%                     3.4%            |
|TERMINAL (d)       |                                                        |           3/65 (5%)                1/77 (1%)       |
|FIRST INCIDENCE    |                                                        |           703                      656             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                                        |                                    P=0.454N        |
|POLY 3             |                                                        |                                    P=0.396N        |
|POLY 1.5           |                                                        |                                    P=0.390N        |
|POLY 6             |                                                        |                                    P=0.404N        |
|LOGISTIC REGRESSION|                                                        |                                    P=0.397N        |
|COCH-ARM / FISHERS |                                                        |                                    P=0.393N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Ovary                                                                                                                            |
|     Cyst                                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                                                        |           22/79 (28%)              24/96 (25%)     |
|POLY-3 ADJUSTED (b)|                                                        |           29.4%                    27.2%           |
|TERMINAL (d)       |                                                        |           19/65 (29%)              23/77 (30%)     |
|FIRST INCIDENCE    |                                                        |           542                      567             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                                        |                                    P=0.458N        |
|POLY 3             |                                                        |                                    P=0.442N        |
|POLY 1.5           |                                                        |                                    P=0.421N        |
|POLY 6             |                                                        |                                    P=0.470N        |
|LOGISTIC REGRESSION|                                                        |                                    P=0.455N        |
|COCH-ARM / FISHERS |                                                        |                                    P=0.399N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 43
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Pancreas                                                                                                                         |
|     Infiltration Cellular Focal Mixed Cell                                                                                      |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  1/99 (1%)                0/98 (0%)    |           7/87 (8%)                12/95 (13%)     |
|POLY-3 ADJUSTED (b)|                  1.1%                     0.0%         |           8.5%                     13.6%           |
|TERMINAL (d)       |                  1/76 (1%)                0/74 (0%)    |           7/70 (10%)               12/77 (16%)     |
|FIRST INCIDENCE    |                  734 (T)                  ---          |           735 (T)                  735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.505N     |                                    P=0.224         |
|POLY 3             |                                           P=0.514N     |                                    P=0.207         |
|POLY 1.5           |                                           P=0.510N     |                                    P=0.214         |
|POLY 6             |                                           P=0.517N     |                                    P=0.198         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.224         |
|COCH-ARM / FISHERS |                                           P=0.503N     |                                    P=0.222         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Pancreas                                                                                                                         |
|     Infiltration Cellular Lymphocyte                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  1/99 (1%)                5/98 (5%)    |           5/87 (6%)                5/95 (5%)       |
|POLY-3 ADJUSTED (b)|                  1.1%                     5.6%         |           6.1%                     5.7%            |
|TERMINAL (d)       |                  0/76 (0%)                5/74 (7%)    |           3/70 (4%)                4/77 (5%)       |
|FIRST INCIDENCE    |                  717                      734 (T)      |           667                      656             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.101      |                                    P=0.583N        |
|POLY 3             |                                           P=0.099      |                                    P=0.578N        |
|POLY 1.5           |                                           P=0.101      |                                    P=0.571N        |
|POLY 6             |                                           P=0.098      |                                    P=0.587N        |
|LOGISTIC REGRESSION|                                           P=0.096      |                                    P=0.576N        |
|COCH-ARM / FISHERS |                                           P=0.103      |                                    P=0.570N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 44
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Pancreas                                                                                                                         |
|     Lipomatosis                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  1/99 (1%)                4/98 (4%)    |           21/87 (24%)              33/95 (35%)     |
|POLY-3 ADJUSTED (b)|                  1.1%                     4.5%         |           25.1%                    36.9%           |
|TERMINAL (d)       |                  0/76 (0%)                3/74 (4%)    |           16/70 (23%)              30/77 (39%)     |
|FIRST INCIDENCE    |                  717                      553          |           334                      567             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.176      |                                    P=0.082         |
|POLY 3             |                                           P=0.175      |                                    P=0.062         |
|POLY 1.5           |                                           P=0.177      |                                    P=0.069         |
|POLY 6             |                                           P=0.174      |                                    P=0.054         |
|LOGISTIC REGRESSION|                                           P=0.186      |                                    P=0.080         |
|COCH-ARM / FISHERS |                                           P=0.181      |                                    P=0.080         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Pancreas                                                                                                                         |
|     Vacuolization Cytoplasmic                                                                                                   |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  16/99 (16%)              28/98 (29%)  |           12/87 (14%)              15/95 (16%)     |
|POLY-3 ADJUSTED (b)|                  17.4%                    31.5%        |           14.6%                    16.9%           |
|TERMINAL (d)       |                  15/76 (20%)              27/74 (37%)  |           12/70 (17%)              13/77 (17%)     |
|FIRST INCIDENCE    |                  715                      729          |           735 (T)                  656             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.021 *    |                                    P=0.431         |
|POLY 3             |                                           P=0.020 *    |                                    P=0.418         |
|POLY 1.5           |                                           P=0.022 *    |                                    P=0.425         |
|POLY 6             |                                           P=0.017 *    |                                    P=0.408         |
|LOGISTIC REGRESSION|                                           P=0.018 *    |                                    P=0.398         |
|COCH-ARM / FISHERS |                                           P=0.027 *    |                                    P=0.434         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 45
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Pancreas: Acinus                                                                                                                 |
|     Atrophy                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  1/99 (1%)                2/98 (2%)    |           0/87 (0%)                0/95 (0%)       |
|POLY-3 ADJUSTED (b)|                  1.1%                     2.2%         |           0.0%                     0.0%            |
|TERMINAL (d)       |                  1/76 (1%)                1/74 (1%)    |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  734 (T)                  620          |           ---                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.491      |                                    (e)             |
|POLY 3             |                                           P=0.493      |                                    (e)             |
|POLY 1.5           |                                           P=0.495      |                                    (e)             |
|POLY 6             |                                           P=0.492      |                                    (e)             |
|LOGISTIC REGRESSION|                                           P=0.504      |                                    (e)             |
|COCH-ARM / FISHERS |                                           P=0.496      |                                    (e)             |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Pancreas: Acinus                                                                                                                 |
|     Cytoplasmic Alteration                                                                                                      |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/99 (0%)                4/98 (4%)    |           1/87 (1%)                5/95 (5%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     4.4%         |           1.2%                     5.6%            |
|TERMINAL (d)       |                  0/76 (0%)                0/74 (0%)    |           1/70 (1%)                1/77 (1%)       |
|FIRST INCIDENCE    |                  ---                      579          |           735 (T)                  458             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.062      |                                    P=0.117         |
|POLY 3             |                                           P=0.062      |                                    P=0.124         |
|POLY 1.5           |                                           P=0.062      |                                    P=0.125         |
|POLY 6             |                                           P=0.062      |                                    P=0.123         |
|LOGISTIC REGRESSION|                                           P=0.079      |                                    P=0.102         |
|COCH-ARM / FISHERS |                                           P=0.059      |                                    P=0.127         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 46
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Pancreas: Duct                                                                                                                   |
|     Cyst                                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  2/99 (2%)                0/98 (0%)    |           1/87 (1%)                2/95 (2%)       |
|POLY-3 ADJUSTED (b)|                  2.2%                     0.0%         |           1.2%                     2.3%            |
|TERMINAL (d)       |                  2/76 (3%)                0/74 (0%)    |           1/70 (1%)                2/77 (3%)       |
|FIRST INCIDENCE    |                  734 (T)                  ---          |           735 (T)                  735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.245N     |                                    P=0.533         |
|POLY 3             |                                           P=0.250N     |                                    P=0.517         |
|POLY 1.5           |                                           P=0.247N     |                                    P=0.519         |
|POLY 6             |                                           P=0.253N     |                                    P=0.513         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.533         |
|COCH-ARM / FISHERS |                                           P=0.251N     |                                    P=0.533         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Parathyroid Gland                                                                                                                |
|     Hyperplasia                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  1/66 (2%)                1/67 (1%)    |           11/63 (17%)              8/58 (14%)      |
|POLY-3 ADJUSTED (b)|                  1.6%                     1.6%         |           18.3%                    14.6%           |
|TERMINAL (d)       |                  1/48 (2%)                0/53 (0%)    |           10/48 (21%)              4/46 (9%)       |
|FIRST INCIDENCE    |                  734 (T)                  533          |           733                      309             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.751N     |                                    P=0.334N        |
|POLY 3             |                                           P=0.747N     |                                    P=0.390N        |
|POLY 1.5           |                                           P=0.750N     |                                    P=0.388N        |
|POLY 6             |                                           P=0.743N     |                                    P=0.394N        |
|LOGISTIC REGRESSION|                                           P=0.733      |                                    P=0.278N        |
|COCH-ARM / FISHERS |                                           P=0.748N     |                                    P=0.382N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 47
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Pituitary Gland: Pars Distalis                                                                                                   |
|     Cyst                                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  9/83 (11%)               14/86 (16%)  |           0/83 (0%)                4/93 (4%)       |
|POLY-3 ADJUSTED (b)|                  11.5%                    17.4%        |           0.0%                     4.7%            |
|TERMINAL (d)       |                  7/66 (11%)               11/67 (16%)  |           0/67 (0%)                4/74 (5%)       |
|FIRST INCIDENCE    |                  617                      667          |           ---                      735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.190      |                                    P=0.078         |
|POLY 3             |                                           P=0.202      |                                    P=0.073         |
|POLY 1.5           |                                           P=0.206      |                                    P=0.074         |
|POLY 6             |                                           P=0.195      |                                    P=0.072         |
|LOGISTIC REGRESSION|                                           P=0.203      |                                    P=0.078         |
|COCH-ARM / FISHERS |                                           P=0.211      |                                    P=0.076         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Pituitary Gland: Pars Distalis                                                                                                   |
|     Hyperplasia Focal                                                                                                           |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  1/83 (1%)                1/86 (1%)    |           37/83 (45%)              35/93 (38%)     |
|POLY-3 ADJUSTED (b)|                  1.3%                     1.3%         |           47.8%                    39.9%           |
|TERMINAL (d)       |                  1/66 (2%)                1/67 (2%)    |           35/67 (52%)              29/74 (39%)     |
|FIRST INCIDENCE    |                  734 (T)                  734 (T)      |           691                      449             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.758N     |                                    P=0.263N        |
|POLY 3             |                                           P=0.752N     |                                    P=0.191N        |
|POLY 1.5           |                                           P=0.750N     |                                    P=0.198N        |
|POLY 6             |                                           P=0.756N     |                                    P=0.188N        |
|LOGISTIC REGRESSION|                                           P=0.758N     |                                    P=0.234N        |
|COCH-ARM / FISHERS |                                           P=0.743N     |                                    P=0.217N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 48
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Preputial Gland                                                                                                                  |
|     Atrophy                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  25/98 (26%)              56/99 (57%)  |                                                    |
|POLY-3 ADJUSTED (b)|                  27.0%                    58.9%        |                                                    |
|TERMINAL (d)       |                  15/75 (20%)              38/74 (51%)  |                                                    |
|FIRST INCIDENCE    |                  624                      533          |                                                    |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P<0.001 **   |                                                    |
|POLY 3             |                                           P<0.001 **   |                                                    |
|POLY 1.5           |                                           P<0.001 **   |                                                    |
|POLY 6             |                                           P<0.001 **   |                                                    |
|LOGISTIC REGRESSION|                                           P<0.001 **   |                                                    |
|COCH-ARM / FISHERS |                                           P<0.001 **   |                                                    |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Preputial Gland                                                                                                                  |
|     Cyst                                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  84/98 (86%)              89/99 (90%)  |                                                    |
|POLY-3 ADJUSTED (b)|                  87.6%                    90.5%        |                                                    |
|TERMINAL (d)       |                  65/75 (87%)              65/74 (88%)  |                                                    |
|FIRST INCIDENCE    |                  386                      415          |                                                    |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.230      |                                                    |
|POLY 3             |                                           P=0.331      |                                                    |
|POLY 1.5           |                                           P=0.292      |                                                    |
|POLY 6             |                                           P=0.386      |                                                    |
|LOGISTIC REGRESSION|                                           P=0.233      |                                                    |
|COCH-ARM / FISHERS |                                           P=0.249      |                                                    |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 49
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Preputial Gland                                                                                                                  |
|     Inflammation                                                                                                                |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  46/98 (47%)              61/99 (62%)  |                                                    |
|POLY-3 ADJUSTED (b)|                  49.8%                    66.0%        |                                                    |
|TERMINAL (d)       |                  39/75 (52%)              52/74 (70%)  |                                                    |
|FIRST INCIDENCE    |                  617                      533          |                                                    |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.019 *    |                                                    |
|POLY 3             |                                           P=0.016 *    |                                                    |
|POLY 1.5           |                                           P=0.019 *    |                                                    |
|POLY 6             |                                           P=0.013 *    |                                                    |
|LOGISTIC REGRESSION|                                           P=0.015 *    |                                                    |
|COCH-ARM / FISHERS |                                           P=0.027 *    |                                                    |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Prostate                                                                                                                         |
|     Infiltration Cellular Lymphocyte                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  2/98 (2%)                6/92 (7%)    |                                                    |
|POLY-3 ADJUSTED (b)|                  2.2%                     7.2%         |                                                    |
|TERMINAL (d)       |                  1/76 (1%)                6/71 (9%)    |                                                    |
|FIRST INCIDENCE    |                  684                      734 (T)      |                                                    |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.119      |                                                    |
|POLY 3             |                                           P=0.115      |                                                    |
|POLY 1.5           |                                           P=0.118      |                                                    |
|POLY 6             |                                           P=0.113      |                                                    |
|LOGISTIC REGRESSION|                                           P=0.111      |                                                    |
|COCH-ARM / FISHERS |                                           P=0.120      |                                                    |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 50
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Prostate: Epithelium                                                                                                             |
|     Hyperplasia                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  49/98 (50%)              45/92 (49%)  |                                                    |
|POLY-3 ADJUSTED (b)|                  52.9%                    52.9%        |                                                    |
|TERMINAL (d)       |                  47/76 (62%)              39/71 (55%)  |                                                    |
|FIRST INCIDENCE    |                  386                      630          |                                                    |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.503N     |                                                    |
|POLY 3             |                                           P=0.561      |                                                    |
|POLY 1.5           |                                           P=0.548N     |                                                    |
|POLY 6             |                                           P=0.562N     |                                                    |
|LOGISTIC REGRESSION|                                           P=0.549      |                                                    |
|COCH-ARM / FISHERS |                                           P=0.498N     |                                                    |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Salivary Glands                                                                                                                  |
|     Infiltration Cellular Lymphocyte                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  66/99 (67%)              69/99 (70%)  |           74/94 (79%)              79/99 (80%)     |
|POLY-3 ADJUSTED (b)|                  70.1%                    73.4%        |           80.9%                    81.9%           |
|TERMINAL (d)       |                  58/76 (76%)              58/74 (78%)  |           60/70 (86%)              64/77 (83%)     |
|FIRST INCIDENCE    |                  520                      415          |           334                      309             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.281      |                                    P=0.509N        |
|POLY 3             |                                           P=0.366      |                                    P=0.500         |
|POLY 1.5           |                                           P=0.371      |                                    P=0.511         |
|POLY 6             |                                           P=0.364      |                                    P=0.479         |
|LOGISTIC REGRESSION|                                           P=0.287      |                                    P=0.487         |
|COCH-ARM / FISHERS |                                           P=0.380      |                                    P=0.497         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 51
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Seminal Vesicle                                                                                                                  |
|     Cyst                                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  80/99 (81%)              58/98 (59%)  |                                                    |
|POLY-3 ADJUSTED (b)|                  82.9%                    62.8%        |                                                    |
|TERMINAL (d)       |                  65/76 (86%)              46/74 (62%)  |                                                    |
|FIRST INCIDENCE    |                  386                      415          |                                                    |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.006N**   |                                                    |
|POLY 3             |                                           P<0.001N**   |                                                    |
|POLY 1.5           |                                           P<0.001N**   |                                                    |
|POLY 6             |                                           P<0.001N**   |                                                    |
|LOGISTIC REGRESSION|                                           P<0.001N**   |                                                    |
|COCH-ARM / FISHERS |                                           P<0.001N**   |                                                    |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Seminal Vesicle                                                                                                                  |
|     Inflammation                                                                                                                |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  2/99 (2%)                0/98 (0%)    |                                                    |
|POLY-3 ADJUSTED (b)|                  2.2%                     0.0%         |                                                    |
|TERMINAL (d)       |                  2/76 (3%)                0/74 (0%)    |                                                    |
|FIRST INCIDENCE    |                  734 (T)                  ---          |                                                    |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.245N     |                                                    |
|POLY 3             |                                           P=0.252N     |                                                    |
|POLY 1.5           |                                           P=0.248N     |                                                    |
|POLY 6             |                                           P=0.256N     |                                                    |
|LOGISTIC REGRESSION|                                           (e)          |                                                    |
|COCH-ARM / FISHERS |                                           P=0.251N     |                                                    |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 52
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Skin                                                                                                                             |
|     Ulcer Focal                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/99 (0%)                1/100 (1%)   |           2/99 (2%)                0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                  0.0%                     1.1%         |           2.2%                     0.0%            |
|TERMINAL (d)       |                  0/76 (0%)                1/74 (1%)    |           1/70 (1%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  ---                      734 (T)      |           691                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.495      |                                    P=0.236N        |
|POLY 3             |                                           P=0.500      |                                    P=0.237N        |
|POLY 1.5           |                                           P=0.500      |                                    P=0.235N        |
|POLY 6             |                                           P=0.500      |                                    P=0.240N        |
|LOGISTIC REGRESSION|                                           P=0.495      |                                    P=0.237N        |
|COCH-ARM / FISHERS |                                           P=0.503      |                                    P=0.246N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Spleen                                                                                                                           |
|     Hematopoietic Cell Proliferation                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  37/99 (37%)              48/98 (49%)  |           74/91 (81%)              92/99 (93%)     |
|POLY-3 ADJUSTED (b)|                  39.2%                    50.7%        |           84.2%                    94.4%           |
|TERMINAL (d)       |                  29/76 (38%)              34/74 (46%)  |           63/70 (90%)              76/77 (99%)     |
|FIRST INCIDENCE    |                  386                      456          |           397                      309             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.072      |                                    P=0.038 *       |
|POLY 3             |                                           P=0.071      |                                    P=0.015 *       |
|POLY 1.5           |                                           P=0.068      |                                    P=0.015 *       |
|POLY 6             |                                           P=0.076      |                                    P=0.013 *       |
|LOGISTIC REGRESSION|                                           P=0.071      |                                    P=0.009 **      |
|COCH-ARM / FISHERS |                                           P=0.067      |                                    P=0.014 *       |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 53
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Spleen                                                                                                                           |
|     Pigmentation                                                                                                                |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/99 (0%)                1/98 (1%)    |           17/91 (19%)              12/99 (12%)     |
|POLY-3 ADJUSTED (b)|                  0.0%                     1.1%         |           20.0%                    13.3%           |
|TERMINAL (d)       |                  0/76 (0%)                0/74 (0%)    |           15/70 (21%)              9/77 (12%)      |
|FIRST INCIDENCE    |                  ---                      620          |           696                      650             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.496      |                                    P=0.153N        |
|POLY 3             |                                           P=0.500      |                                    P=0.158N        |
|POLY 1.5           |                                           P=0.500      |                                    P=0.152N        |
|POLY 6             |                                           P=0.500      |                                    P=0.166N        |
|LOGISTIC REGRESSION|                                           P=0.511      |                                    P=0.174N        |
|COCH-ARM / FISHERS |                                           P=0.497      |                                    P=0.146N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Spleen: Lymphoid Follicle                                                                                                        |
|     Atrophy                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  11/99 (11%)              8/98 (8%)    |           6/91 (7%)                3/99 (3%)       |
|POLY-3 ADJUSTED (b)|                  11.6%                    8.8%         |           6.9%                     3.3%            |
|TERMINAL (d)       |                  1/76 (1%)                1/74 (1%)    |           1/70 (1%)                1/77 (1%)       |
|FIRST INCIDENCE    |                  520                      581          |           552                      481             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.355N     |                                    P=0.245N        |
|POLY 3             |                                           P=0.346N     |                                    P=0.220N        |
|POLY 1.5           |                                           P=0.337N     |                                    P=0.213N        |
|POLY 6             |                                           P=0.357N     |                                    P=0.231N        |
|LOGISTIC REGRESSION|                                           P=0.269N     |                                    P=0.181N        |
|COCH-ARM / FISHERS |                                           P=0.324N     |                                    P=0.209N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 54
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Spleen: Lymphoid Follicle                                                                                                        |
|     Hyperplasia                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  21/99 (21%)              19/98 (19%)  |           31/91 (34%)              40/99 (40%)     |
|POLY-3 ADJUSTED (b)|                  22.8%                    21.3%        |           36.5%                    44.2%           |
|TERMINAL (d)       |                  20/76 (26%)              19/74 (26%)  |           31/70 (44%)              39/77 (51%)     |
|FIRST INCIDENCE    |                  683                      734 (T)      |           735 (T)                  534             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.469N     |                                    P=0.224         |
|POLY 3             |                                           P=0.473N     |                                    P=0.185         |
|POLY 1.5           |                                           P=0.460N     |                                    P=0.202         |
|POLY 6             |                                           P=0.488N     |                                    P=0.166         |
|LOGISTIC REGRESSION|                                           P=0.490N     |                                    P=0.138         |
|COCH-ARM / FISHERS |                                           P=0.444N     |                                    P=0.226         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Spleen: Red Pulp                                                                                                                 |
|     Atrophy                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/99 (0%)                4/98 (4%)    |           2/91 (2%)                0/99 (0%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     4.4%         |           2.3%                     0.0%            |
|TERMINAL (d)       |                  0/76 (0%)                0/74 (0%)    |           0/70 (0%)                0/77 (0%)       |
|FIRST INCIDENCE    |                  ---                      581          |           542                      ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.062      |                                    P=0.236N        |
|POLY 3             |                                           P=0.062      |                                    P=0.222N        |
|POLY 1.5           |                                           P=0.062      |                                    P=0.217N        |
|POLY 6             |                                           P=0.062      |                                    P=0.228N        |
|LOGISTIC REGRESSION|                                           P=0.068      |                                    P=0.206N        |
|COCH-ARM / FISHERS |                                           P=0.059      |                                    P=0.228N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 55
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Stomach, Forestomach: Epithelium                                                                                                 |
|     Atrophy                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  9/99 (9%)                8/99 (8%)    |           6/91 (7%)                6/97 (6%)       |
|POLY-3 ADJUSTED (b)|                  9.8%                     8.9%         |           7.0%                     6.7%            |
|TERMINAL (d)       |                  8/76 (11%)               6/74 (8%)    |           4/70 (6%)                6/77 (8%)       |
|FIRST INCIDENCE    |                  715                      680          |           701                      735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.529N     |                                    P=0.565N        |
|POLY 3             |                                           P=0.522N     |                                    P=0.579N        |
|POLY 1.5           |                                           P=0.514N     |                                    P=0.573N        |
|POLY 6             |                                           P=0.530N     |                                    P=0.590N        |
|LOGISTIC REGRESSION|                                           P=0.535N     |                                    P=0.591N        |
|COCH-ARM / FISHERS |                                           P=0.500N     |                                    P=0.571N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Stomach, Forestomach: Epithelium                                                                                                 |
|     Hyperplasia                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/99 (0%)                1/99 (1%)    |           4/91 (4%)                5/97 (5%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     1.1%         |           4.7%                     5.6%            |
|TERMINAL (d)       |                  0/76 (0%)                0/74 (0%)    |           4/70 (6%)                4/77 (5%)       |
|FIRST INCIDENCE    |                  ---                      630          |           735 (T)                  701             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.496      |                                    P=0.550         |
|POLY 3             |                                           P=0.500      |                                    P=0.530         |
|POLY 1.5           |                                           P=0.500      |                                    P=0.533         |
|POLY 6             |                                           P=0.500      |                                    P=0.524         |
|LOGISTIC REGRESSION|                                           P=0.529      |                                    P=0.521         |
|COCH-ARM / FISHERS |                                           P=0.500      |                                    P=0.540         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 56
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Stomach, Glandular                                                                                                               |
|     Infiltration Cellular Lymphocyte                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/94 (0%)                0/93 (0%)    |           7/86 (8%)                5/94 (5%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           8.6%                     5.8%            |
|TERMINAL (d)       |                  0/76 (0%)                0/74 (0%)    |           7/70 (10%)               5/77 (7%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           735 (T)                  735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.318N        |
|POLY 3             |                                           (e)          |                                    P=0.339N        |
|POLY 1.5           |                                           (e)          |                                    P=0.330N        |
|POLY 6             |                                           (e)          |                                    P=0.352N        |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.318N        |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.323N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Stomach, Glandular: Epithelium                                                                                                   |
|     Atrophy                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  8/94 (9%)                10/93 (11%)  |           14/86 (16%)              28/94 (30%)     |
|POLY-3 ADJUSTED (b)|                  9.0%                     11.4%        |           16.7%                    31.9%           |
|TERMINAL (d)       |                  7/76 (9%)                6/74 (8%)    |           8/70 (11%)               24/77 (31%)     |
|FIRST INCIDENCE    |                  715                      547          |           334                      567             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.377      |                                    P=0.026 *       |
|POLY 3             |                                           P=0.392      |                                    P=0.015 *       |
|POLY 1.5           |                                           P=0.393      |                                    P=0.018 *       |
|POLY 6             |                                           P=0.391      |                                    P=0.013 *       |
|LOGISTIC REGRESSION|                                           P=0.392      |                                    P=0.027 *       |
|COCH-ARM / FISHERS |                                           P=0.393      |                                    P=0.024 *       |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 57
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Stomach, Glandular: Epithelium                                                                                                   |
|     Cyst Focal                                                                                                                  |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  6/94 (6%)                11/93 (12%)  |           23/86 (27%)              20/94 (21%)     |
|POLY-3 ADJUSTED (b)|                  6.8%                     12.7%        |           28.0%                    22.9%           |
|TERMINAL (d)       |                  6/76 (8%)                10/74 (14%)  |           20/70 (29%)              19/77 (25%)     |
|FIRST INCIDENCE    |                  734 (T)                  668          |           608                      458             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.140      |                                    P=0.250N        |
|POLY 3             |                                           P=0.143      |                                    P=0.278N        |
|POLY 1.5           |                                           P=0.146      |                                    P=0.262N        |
|POLY 6             |                                           P=0.141      |                                    P=0.304N        |
|LOGISTIC REGRESSION|                                           P=0.136      |                                    P=0.278N        |
|COCH-ARM / FISHERS |                                           P=0.149      |                                    P=0.247N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Testes                                                                                                                           |
|     Atrophy                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  3/99 (3%)                2/98 (2%)    |                                                    |
|POLY-3 ADJUSTED (b)|                  3.3%                     2.2%         |                                                    |
|TERMINAL (d)       |                  1/76 (1%)                0/74 (0%)    |                                                    |
|FIRST INCIDENCE    |                  684                      605          |                                                    |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.524N     |                                                    |
|POLY 3             |                                           P=0.517N     |                                                    |
|POLY 1.5           |                                           P=0.513N     |                                                    |
|POLY 6             |                                           P=0.521N     |                                                    |
|LOGISTIC REGRESSION|                                           P=0.483N     |                                                    |
|COCH-ARM / FISHERS |                                           P=0.505N     |                                                    |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 58
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Thymus                                                                                                                           |
|     Angiectasis                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/69 (0%)                0/60 (0%)    |           1/78 (1%)                2/89 (2%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           1.4%                     2.4%            |
|TERMINAL (d)       |                  0/54 (0%)                0/46 (0%)    |           1/62 (2%)                2/71 (3%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           735 (T)                  735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.547         |
|POLY 3             |                                           (e)          |                                    P=0.526         |
|POLY 1.5           |                                           (e)          |                                    P=0.528         |
|POLY 6             |                                           (e)          |                                    P=0.523         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.547         |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.550         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Thymus                                                                                                                           |
|     Atrophy                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  62/69 (90%)              44/60 (73%)  |           22/78 (28%)              27/89 (30%)     |
|POLY-3 ADJUSTED (b)|                  90.1%                    74.3%        |           29.5%                    31.2%           |
|TERMINAL (d)       |                  48/54 (89%)              32/46 (70%)  |           14/62 (23%)              16/71 (23%)     |
|FIRST INCIDENCE    |                  386                      415          |           608                      309             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.060N     |                                    P=0.380         |
|POLY 3             |                                           P=0.016N*    |                                    P=0.471         |
|POLY 1.5           |                                           P=0.014N*    |                                    P=0.466         |
|POLY 6             |                                           P=0.018N*    |                                    P=0.469         |
|LOGISTIC REGRESSION|                                           P=0.013N*    |                                    P=0.471         |
|COCH-ARM / FISHERS |                                           P=0.013N*    |                                    P=0.448         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 59
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Thymus                                                                                                                           |
|     Cyst Focal                                                                                                                  |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  4/69 (6%)                5/60 (8%)    |           5/78 (6%)                3/89 (3%)       |
|POLY-3 ADJUSTED (b)|                  6.3%                     9.1%         |           6.8%                     3.7%            |
|TERMINAL (d)       |                  4/54 (7%)                5/46 (11%)   |           5/62 (8%)                3/71 (4%)       |
|FIRST INCIDENCE    |                  734 (T)                  734 (T)      |           735 (T)                  735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.401      |                                    P=0.287N        |
|POLY 3             |                                           P=0.424      |                                    P=0.292N        |
|POLY 1.5           |                                           P=0.424      |                                    P=0.287N        |
|POLY 6             |                                           P=0.423      |                                    P=0.299N        |
|LOGISTIC REGRESSION|                                           P=0.401      |                                    P=0.287N        |
|COCH-ARM / FISHERS |                                           P=0.412      |                                    P=0.289N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Thymus                                                                                                                           |
|     Hemorrhage                                                                                                                  |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  1/69 (1%)                0/60 (0%)    |           0/78 (0%)                2/89 (2%)       |
|POLY-3 ADJUSTED (b)|                  1.6%                     0.0%         |           0.0%                     2.4%            |
|TERMINAL (d)       |                  0/54 (0%)                0/46 (0%)    |           0/62 (0%)                2/71 (3%)       |
|FIRST INCIDENCE    |                  582                      ---          |           ---                      735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.509N     |                                    P=0.269         |
|POLY 3             |                                           P=0.559N     |                                    P=0.250         |
|POLY 1.5           |                                           P=0.557N     |                                    P=0.252         |
|POLY 6             |                                           P=0.561N     |                                    P=0.249         |
|LOGISTIC REGRESSION|                                           P=0.533N     |                                    P=0.269         |
|COCH-ARM / FISHERS |                                           P=0.535N     |                                    P=0.283         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 60
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Thymus                                                                                                                           |
|     Hyperplasia Lymphoid                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  3/69 (4%)                5/60 (8%)    |           31/78 (40%)              25/89 (28%)     |
|POLY-3 ADJUSTED (b)|                  4.7%                     9.1%         |           42.4%                    30.2%           |
|TERMINAL (d)       |                  2/54 (4%)                5/46 (11%)   |           31/62 (50%)              23/71 (32%)     |
|FIRST INCIDENCE    |                  534                      734 (T)      |           735 (T)                  458             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.282      |                                    P=0.069N        |
|POLY 3             |                                           P=0.289      |                                    P=0.075N        |
|POLY 1.5           |                                           P=0.291      |                                    P=0.073N        |
|POLY 6             |                                           P=0.287      |                                    P=0.079N        |
|LOGISTIC REGRESSION|                                           P=0.284      |                                    P=0.097N        |
|COCH-ARM / FISHERS |                                           P=0.284      |                                    P=0.077N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Thymus: Thymocyte                                                                                                                |
|     Necrosis                                                                                                                    |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/69 (0%)                0/60 (0%)    |           0/78 (0%)                3/89 (3%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           0.0%                     3.6%            |
|TERMINAL (d)       |                  0/54 (0%)                0/46 (0%)    |           0/62 (0%)                0/71 (0%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           ---                      458             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.125         |
|POLY 3             |                                           (e)          |                                    P=0.136         |
|POLY 1.5           |                                           (e)          |                                    P=0.137         |
|POLY 6             |                                           (e)          |                                    P=0.135         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.144         |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.149         |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 61
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Thyroid Gland                                                                                                                    |
|     Inflammation Focal                                                                                                          |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/99 (0%)                0/98 (0%)    |           2/92 (2%)                2/98 (2%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           2.3%                     2.3%            |
|TERMINAL (d)       |                  0/76 (0%)                0/72 (0%)    |           1/70 (1%)                2/75 (3%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           461                      735 (T)         |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.673N        |
|POLY 3             |                                           (e)          |                                    P=0.688N        |
|POLY 1.5           |                                           (e)          |                                    P=0.679N        |
|POLY 6             |                                           (e)          |                                    P=0.690         |
|LOGISTIC REGRESSION|                                           (e)          |                                    P=0.636N        |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.665N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Thyroid Gland: Follicle                                                                                                          |
|     Cyst                                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  5/99 (5%)                9/98 (9%)    |           21/92 (23%)              37/98 (38%)     |
|POLY-3 ADJUSTED (b)|                  5.4%                     10.1%        |           24.2%                    41.2%           |
|TERMINAL (d)       |                  4/76 (5%)                6/72 (8%)    |           20/70 (29%)              31/75 (41%)     |
|FIRST INCIDENCE    |                  718                      579          |           701                      567             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.182      |                                    P=0.019 *       |
|POLY 3             |                                           P=0.186      |                                    P=0.011 *       |
|POLY 1.5           |                                           P=0.190      |                                    P=0.013 *       |
|POLY 6             |                                           P=0.181      |                                    P=0.009 **      |
|LOGISTIC REGRESSION|                                           P=0.188      |                                    P=0.008 **      |
|COCH-ARM / FISHERS |                                           P=0.198      |                                    P=0.019 *       |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 62
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Thyroid Gland: Follicular Cell                                                                                                   |
|     Hyperplasia Focal                                                                                                           |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  0/99 (0%)                0/98 (0%)    |           3/92 (3%)                0/98 (0%)       |
|POLY-3 ADJUSTED (b)|                  0.0%                     0.0%         |           3.5%                     0.0%            |
|TERMINAL (d)       |                  0/76 (0%)                0/72 (0%)    |           3/70 (4%)                0/75 (0%)       |
|FIRST INCIDENCE    |                  ---                      ---          |           735 (T)                  ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           (e)          |                                    P=0.111N        |
|POLY 3             |                                           (e)          |                                    P=0.117N        |
|POLY 1.5           |                                           (e)          |                                    P=0.113N        |
|POLY 6             |                                           (e)          |                                    P=0.121N        |
|LOGISTIC REGRESSION|                                           (e)          |                                    (e)             |
|COCH-ARM / FISHERS |                                           (e)          |                                    P=0.112N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Urinary Bladder                                                                                                                  |
|     Infiltration Cellular Lymphocyte                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                  4/98 (4%)                4/94 (4%)    |           8/79 (10%)               5/92 (5%)       |
|POLY-3 ADJUSTED (b)|                  4.4%                     4.6%         |           10.6%                    5.9%            |
|TERMINAL (d)       |                  4/76 (5%)                4/74 (5%)    |           8/67 (12%)               4/76 (5%)       |
|FIRST INCIDENCE    |                  734 (T)                  734 (T)      |           735 (T)                  715             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                           P=0.627      |                                    P=0.212N        |
|POLY 3             |                                           P=0.611      |                                    P=0.203N        |
|POLY 1.5           |                                           P=0.615      |                                    P=0.197N        |
|POLY 6             |                                           P=0.608      |                                    P=0.212N        |
|LOGISTIC REGRESSION|                                           P=0.627      |                                    P=0.225N        |
|COCH-ARM / FISHERS |                                           P=0.616      |                                    P=0.194N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 63
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Uterus                                                                                                                           |
|     Angiectasis                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                                                        |           1/92 (1%)                3/100 (3%)      |
|POLY-3 ADJUSTED (b)|                                                        |           1.2%                     3.3%            |
|TERMINAL (d)       |                                                        |           1/70 (1%)                2/77 (3%)       |
|FIRST INCIDENCE    |                                                        |           735 (T)                  567             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                                        |                                    P=0.336         |
|POLY 3             |                                                        |                                    P=0.322         |
|POLY 1.5           |                                                        |                                    P=0.325         |
|POLY 6             |                                                        |                                    P=0.318         |
|LOGISTIC REGRESSION|                                                        |                                    P=0.345         |
|COCH-ARM / FISHERS |                                                        |                                    P=0.343         |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Uterus                                                                                                                           |
|     Hydrometra                                                                                                                  |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                                                        |           48/92 (52%)              48/100 (48%)    |
|POLY-3 ADJUSTED (b)|                                                        |           54.5%                    50.5%           |
|TERMINAL (d)       |                                                        |           38/70 (54%)              37/77 (48%)     |
|FIRST INCIDENCE    |                                                        |           542                      449             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                                        |                                    P=0.364N        |
|POLY 3             |                                                        |                                    P=0.344N        |
|POLY 1.5           |                                                        |                                    P=0.335N        |
|POLY 6             |                                                        |                                    P=0.360N        |
|LOGISTIC REGRESSION|                                                        |                                    P=0.358N        |
|COCH-ARM / FISHERS |                                                        |                                    P=0.332N        |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 64
                     Statistical Analysis of Non-neoplastic Lesions in       Mice(B6C3F1)  -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Uterus                                                                                                                           |
|     Inflammation                                                                                                                |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                                                        |           2/92 (2%)                0/100 (0%)      |
|POLY-3 ADJUSTED (b)|                                                        |           2.3%                     0.0%            |
|TERMINAL (d)       |                                                        |           2/70 (3%)                0/77 (0%)       |
|FIRST INCIDENCE    |                                                        |           735 (T)                  ---             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                                        |                                    P=0.218N        |
|POLY 3             |                                                        |                                    P=0.222N        |
|POLY 1.5           |                                                        |                                    P=0.217N        |
|POLY 6             |                                                        |                                    P=0.228N        |
|LOGISTIC REGRESSION|                                                        |                                    (e)             |
|COCH-ARM / FISHERS |                                                        |                                    P=0.228N        |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |                  SHAM                     10 GAUSS     |           SHAM                     10 GAUSS        |
|                   |                  CONTROL                   INTER.      |           CONTROL                   INTER.         |
|=================================================================================================================================|
|                                                                                                                                 |
|Uterus: Endometrium                                                                                                              |
|     Hyperplasia Cystic                                                                                                          |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                                                        |           54/92 (59%)              62/100 (62%)    |
|POLY-3 ADJUSTED (b)|                                                        |           60.4%                    65.8%           |
|TERMINAL (d)       |                                                        |           43/70 (61%)              51/77 (66%)     |
|FIRST INCIDENCE    |                                                        |           334                      449             |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                                        |                                    P=0.365         |
|POLY 3             |                                                        |                                    P=0.270         |
|POLY 1.5           |                                                        |                                    P=0.307         |
|POLY 6             |                                                        |                                    P=0.233         |
|LOGISTIC REGRESSION|                                                        |                                    P=0.337         |
|COCH-ARM / FISHERS |                                                        |                                    P=0.374         |
|=================================================================================================================================|

(a)  Number of tumor-bearing animals /  number of animals examined at site.
(b)  Poly-3 adjusted lifetime tumor incidence.
(d)  Observed incidence at terminal kill.
(f)  Beneath the control incidence are the P-values associated with the trend 
test.  Beneath the dosed group incidence are the P-values corresponding to 
pairwise comparisons between the controls and that dosed group.  The life
table analysis regards tumors in animals dying prior to  terminal kill as
 being (directly or indirectly) the cause of death.
Logistic regression is an alternative
 method for analyzing the incidence of non-fatal tumors. The Cochran-Armitage
and Fishers exact tests compare directly the overall incidence rates
For all tests a negative trend is indicated by N
(e)  Value of Statistic cannot be computed.
(I)  Interim sacrifice
(T)  Terminal sacrifice
#   Tumor rates based on number of animals necropsied.
*   To the right of any statistical result, indicates significance at (P<=0.05).
**  To the right of any statistical result, indicates significance at (P<=0.01).
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.