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TDMS Study 89029-13 Pathology Tables

NTP Experiment-Test: 89029-13  INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a)      Report: PEIRPT05
Study Type: SUBCHRON 90-DAY                    MAGNETIC FIELDS + DMBA INITIATION PROMOTION                        Date: 12/20/97
Route: MAGNETIC FIELDS                                                                                            Time: 14:41:29

                              8MG(2MGX4)DMBA VS 50 HZ/1G 8MG(2MGX4)DMBA VS 50 HZ/5G 8MG(2MGX4)DMBA




       Facility:  Battelle Northwest

       Chemical CAS #:  EMF + DMBA

       Lock Date:  10/24/97

       Cage Range:  All

       Reasons For Removal:    All

       Removal Date Range:     All

       Treatment Groups:       Include All


































a  Number of animals examined microscopically at site and number of animals with lesion

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NTP Experiment-Test: 89029-13  INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a)      Report: PEIRPT05
Study Type: SUBCHRON 90-DAY                    MAGNETIC FIELDS + DMBA INITIATION PROMOTION                        Date: 12/20/97  
Route: MAGNETIC FIELDS                                                                                            Time: 14:41:29  
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         SPRAGUE-DAWLEY RATS FEMALE                8 DMBA       50 HZ/1G     50 HZ/5G                                               
                                                   CONTROL       8 DMBA       8 DMBA                                                
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DISPOSITION SUMMARY                                                                                                                 

  Animals Initially in Study                         100          100          100                                                  
  Early Deaths                                                                                                                      
    Moribund Sacrifice                                                           1                                                  
  Survivors                                                                                                                         
    Terminal Sacrifice                               100          100           99                                                  

  Animals Examined Microscopically                   100          100          100                                                  
                                                                                                                                    
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 ALIMENTARY SYSTEM                                                                                                                  
                                                                                                                                    
   None                                                                                                                             
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 CARDIOVASCULAR SYSTEM                                                                                                              
                                                                                                                                    
   None                                                                                                                             
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 ENDOCRINE SYSTEM                                                                                                                   
                                                                                                                                    
   None                                                                                                                             
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 GENERAL BODY SYSTEM                                                                                                                
                                                                                                                                    
   None                                                                                                                             
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 GENITAL SYSTEM                                                                                                                     
                                                                                                                                    
   Clitoral Gland                                                  (1)                                                              
      Carcinoma                                                     1 (100%)                                                        
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 HEMATOPOIETIC SYSTEM                                                                                                               
                                                                                                                                    
   None                                                                                                                             
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                                                             Page   2                                                               
NTP Experiment-Test: 89029-13  INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a)      Report: PEIRPT05
Study Type: SUBCHRON 90-DAY                    MAGNETIC FIELDS + DMBA INITIATION PROMOTION                        Date: 12/20/97  
Route: MAGNETIC FIELDS                                                                                            Time: 14:41:29  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         SPRAGUE-DAWLEY RATS FEMALE                8 DMBA       50 HZ/1G     50 HZ/5G                                               
                                                   CONTROL       8 DMBA       8 DMBA                                                
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 INTEGUMENTARY SYSTEM                                                                                                               
                                                                                                                                    
   Mammary Gland                                      (100)        (100)        (100)                                               
      Adenoma                                                                    1 (1%)                                             
      Carcinoma                                       20 (20%)     24 (24%)     15 (15%)                                            
      Carcinoma, Multiple                             23 (23%)     24 (24%)     23 (23%)                                            
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 MUSCULOSKELETAL SYSTEM                                                                                                             
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 NERVOUS SYSTEM                                                                                                                     
                                                                                                                                    
   None                                                                                                                             
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 RESPIRATORY SYSTEM                                                                                                                 
                                                                                                                                    
   None                                                                                                                             
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 SPECIAL SENSES SYSTEM                                                                                                              
                                                                                                                                    
   None                                                                                                                             
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 URINARY SYSTEM                                                                                                                     
                                                                                                                                    
   None                                                                                                                             
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 SYSTEMIC LESIONS                                                                                                                   

   Multiple Organs                                   *(100)       *(100)       *(100)                                               
      Leukemia Mononuclear                                                       1 (1%)                                             
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     *   Number of animals with any tissue examined microscopically                                                                 

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NTP Experiment-Test: 89029-13  INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a)      Report: PEIRPT05
Study Type: SUBCHRON 90-DAY                    MAGNETIC FIELDS + DMBA INITIATION PROMOTION                        Date: 12/20/97  
Route: MAGNETIC FIELDS                                                                                            Time: 14:41:29  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         SPRAGUE-DAWLEY RATS FEMALE                8 DMBA       50 HZ/1G     50 HZ/5G                                               
                                                   CONTROL       8 DMBA       8 DMBA                                                
____________________________________________________________________________________________________________________________________
                                                                                                                                    
TUMOR SUMMARY                                                                                                                       
                                                                                                                                    
   Total Animals with Primary Neoplasms (b)            43          48          38                                                   
     Total Primary Neoplasms                           43          49          40                                                   
                                                                                                                                    
   Total Animals with Benign Neoplasms                                          1                                                   
     Total Benign Neoplasms                                                     1                                                   
                                                                                                                                    
   Total Animals with Malignant Neoplasms              43          48          38                                                   
     Total Malignant Neoplasms                         43          49          39                                                   
                                                                                                                                    
   Total Animals with Metastatic Neoplasms                                                                                          
     Total Metastatic Neoplasm                                                                                                      
                                                                                                                                    
   Total Animals with Malignant Neoplasms                                                                                           
   Uncertain Primary Site                                                                                                           
                                                                                                                                    
   Total Animals with Neoplasms Uncertain-                                                                                          
   Benign or Malignant                                                                                                              
     Total Uncertain Neoplasms                                                                                                      
                                                                                                                                    

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a  Number of animals examined microscopically at site and number of animals with lesion                                             
b  Primary tumors: all tumors except metastatic tumors                                                                              

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