National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/4386

TDMS Study 93026-06 Pathology Tables

NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18

                                                      Final#1, Revision#2




       Facility:  Battelle Northwest

       Chemical CAS #:  91-17-8

       Lock Date:  01/04/01

       Cage Range:  All

       Reasons For Removal:    25022 Accidently Killed                 25019 Moribund Sacrifice
                               25020 Natural Death                     25021 Terminal Sacrifice

       Removal Date Range:     All

       Treatment Groups:       Include All

































Note:  Animals arranged according to CID number

                                                              Page   1


NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 7| 7| 7| 3| 7| 7| 6| 7| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 0| 3| 3| 1| 3| 3| 3| 3| 3| 6| 3| 3| 3| 3| 6| 3| 3| 7| 3| 3| 3| 3| 3| 3|             
                                           | 8| 3| 5| 5| 4| 5| 6| 7| 7| 7| 8| 6| 7| 5| 6| 3| 6| 6| 2| 7| 6| 6| 7| 7| 7|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    CONTROL                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |__________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Gallbladder                             | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  M|             
                                           |__________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +|             
      Leiomyoma                            |                               X                                          |             
                                           |__________________________________________________________________________|             
   Intestine Small, Duodenum               | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Ileum                  | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hepatocellular Carcinoma             |    X                       X                                             |             
      Hepatocellular Adenoma               |                         X        X                       X               |             
      Hepatocellular Adenoma, Multiple     |                                                                          |             
      Lymphoma Malignant                   | X           X                    X           X                           |             
                                           |__________________________________________________________________________|             
   Mesentery                               |       +     +  +  +     +     +     +                                   +|             
      Lymphoma Malignant                   |                                                                          |             
                                           |__________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   | X                             X  X           X                           |             
                                           |__________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   | X                                X           X  X                        |             
                                           |__________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   | X                             X              X                           |             
                                           |__________________________________________________________________________|             
   Stomach, Glandular                      | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page   2                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 7| 7| 7| 3| 7| 7| 6| 7| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 0| 3| 3| 1| 3| 3| 3| 3| 3| 6| 3| 3| 3| 3| 6| 3| 3| 7| 3| 3| 3| 3| 3| 3|             
                                           | 8| 3| 5| 5| 4| 5| 6| 7| 7| 7| 8| 6| 7| 5| 6| 3| 6| 6| 2| 7| 6| 6| 7| 7| 7|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    CONTROL                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
      Lymphoma Malignant                   |                                              X                           |             
                                           |__________________________________________________________________________|             
   Tongue                                  |                                                                          |             
      Squamous Cell Carcinoma              |                                                                          |             
                                           |__________________________________________________________________________|             
   Tooth                                   |                                  +              +                        |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                              X                           |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |__________________________________________________________________________|             
   Adrenal Cortex                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |             X                                                            |             
      Subcapsular, Adenoma                 |                                                                          |             
                                           |__________________________________________________________________________|             
   Adrenal Medulla                         | +  +  +  +  +  I  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Pheochromocytoma Benign              |                                                                X         |             
                                           |__________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Adenoma                              |                                                                          |             
                                           |__________________________________________________________________________|             
   Parathyroid Gland                       | +  +  +  +  M  +  M  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  M  +|             
                                           |__________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                                                          |             
      Pars Distalis, Adenoma               |       X        X     X                          X           X            |             
      Pars Intermedia, Adenoma             |                                                                          |             
                                           |__________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Follicular Cell, Adenoma             |             X                                                            |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
    None                                   |                                                                          |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page   3                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 7| 7| 7| 3| 7| 7| 6| 7| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 0| 3| 3| 1| 3| 3| 3| 3| 3| 6| 3| 3| 3| 3| 6| 3| 3| 7| 3| 3| 3| 3| 3| 3|             
                                           | 8| 3| 5| 5| 4| 5| 6| 7| 7| 7| 8| 6| 7| 5| 6| 3| 6| 6| 2| 7| 6| 6| 7| 7| 7|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    CONTROL                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6|             
 __________________________________________|__________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Clitoral Gland                          | M  +  +  +  +  +  +  M  +  +  +  +  +  M  +  M  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Ovary                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Cystadenoma                          |                                                          X               |             
      Granulosa Cell Tumor Benign          |                                                                          |             
      Hemangioma                           |                X                                                         |             
      Luteoma                              |                                                    X                     |             
      Lymphoma Malignant                   | X                             X  X           X                           |             
                                           |__________________________________________________________________________|             
   Uterus                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Carcinoma                            |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |__________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   | X           X                    X                                       |             
                                           |__________________________________________________________________________|             
   Lymph Node                              |             +  +                 +           +                           |             
      Iliac, Lymphoma Malignant            |             X  X                             X                           |             
      Lumbar, Lymphoma Malignant           |                                  X                                       |             
      Pancreatic, Lymphoma Malignant       |                                  X                                       |             
      Renal, Lymphoma Malignant            |             X  X                 X           X                           |             
                                           |__________________________________________________________________________|             
   Lymph Node, Bronchial                   | +  +  +  +  +  +  M  +  M  +  +  +  +  +  M  +  +  +  M  +  +  +  +  +  +|             
      Lymphoma Malignant                   | X           X  X                 X           X                           |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mandibular                  | +  +  +  M  +  +  M  +  +  M  +  +  M  M  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   | X           X  X                 X           X  X                        |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   | X              X              X  X           X  X                        |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mediastinal                 | +  +  M  +  +  +  +  +  +  +  +  +  +  M  +  +  +  M  +  +  +  +  +  M  +|             
      Lymphoma Malignant                   | X           X  X                 X           X  X                        |             
                                           |__________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page   4                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 7| 7| 7| 3| 7| 7| 6| 7| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 0| 3| 3| 1| 3| 3| 3| 3| 3| 6| 3| 3| 3| 3| 6| 3| 3| 7| 3| 3| 3| 3| 3| 3|             
                                           | 8| 3| 5| 5| 4| 5| 6| 7| 7| 7| 8| 6| 7| 5| 6| 3| 6| 6| 2| 7| 6| 6| 7| 7| 7|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    CONTROL                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6|             
 __________________________________________|__________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Hemangiosarcoma                      |             X                                                            |             
      Lymphoma Malignant                   | X           X  X              X  X           X  X                        |             
                                           |__________________________________________________________________________|             
   Thymus                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   | X           X  X                 X           X  X                        |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |__________________________________________________________________________|             
   Mammary Gland                           | +  +  +  +  I  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Carcinoma                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Subcutaneous Tissue, Sarcoma         |             X  X                                                         |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |__________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Peripheral Nerve                        |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |__________________________________________________________________________|             
   Larynx                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                              X                           |             
                                           |__________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Alveolar/Bronchiolar Adenoma         |                                                                          |             
      Alveolar/Bronchiolar Carcinoma       |          X        X        X           X                                 |             
      Hepatocellular Carcinoma, Metastatic,|                                                                          |             
           Liver                           |                            X                                             |             
      Lymphoma Malignant                   | X           X  X              X  X           X  X                        |             
      Mediastinum, Alveolar/Bronchiolar    |                                                                          |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page   5                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 7| 7| 7| 3| 7| 7| 6| 7| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 0| 3| 3| 1| 3| 3| 3| 3| 3| 6| 3| 3| 3| 3| 6| 3| 3| 7| 3| 3| 3| 3| 3| 3|             
                                           | 8| 3| 5| 5| 4| 5| 6| 7| 7| 7| 8| 6| 7| 5| 6| 3| 6| 6| 2| 7| 6| 6| 7| 7| 7|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    CONTROL                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6|             
 __________________________________________|__________________________________________________________________________|             
 RESPIRATORY SYSTEM - cont                 |                                                                          |             
                                           |                                                                          |             
          Carcinoma, Metastatic, Lung      |                                                                          |             
                                           |__________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   | X                                                                        |             
                                           |__________________________________________________________________________|             
   Pleura                                  |                                                                          |             
                                           |__________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Ear                                     |                      +                                                   |             
                                           |__________________________________________________________________________|             
   Eye                                     |                                                       +                  |             
                                           |__________________________________________________________________________|             
   Harderian Gland                         | +                                                  +                    +|             
      Adenoma                              | X                                                                       X|             
      Carcinoma                            |                                                    X                     |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Metastatic, Lung                 |                                                                          |             
      Lymphoma Malignant                   | X           X                 X              X                           |             
                                           |__________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   | X              X                 X           X  X                        |             
 __________________________________________|__________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   | X           X  X              X  X           X  X                        |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page   6                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 6| 7| 7| 5| 7| 7| 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 6| 7| 6|  |            |
                             DAY ON TEST   | 3| 3| 3| 3| 0| 1| 3| 3| 9| 3| 3| 3| 3| 5| 3| 3| 3| 3| 3| 3| 3| 1| 3| 5|  |            |
                                           | 7| 7| 5| 6| 0| 0| 7| 7| 9| 5| 6| 6| 6| 9| 7| 6| 7| 5| 6| 5| 7| 6| 6| 9|  |            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|  |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|  |     T      |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|  |     A      |
    CONTROL                                | 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|  |     L      |
                                           | 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|  |            |
 _____________________________________________________________________________________________________________________|____________|
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
                                           |__________________________________________________________________________|____________|
   Gallbladder                             | I  +  I  I  +  +  M  +  +  +  +  +  +  +  I  +  +  +  +  +  +  +  +  +   |  41        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  48        |
      Leiomyoma                            |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  48        |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  48        |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  47        |
                                           |__________________________________________________________________________|____________|
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Hepatocellular Carcinoma             |    X                                                              X      |          4 |
      Hepatocellular Adenoma               |                                                             X            |          4 |
      Hepatocellular Adenoma, Multiple     |                   X                          X        X                  |          3 |
      Lymphoma Malignant                   | X                                      X                                 |          6 |
                                           |__________________________________________________________________________|____________|
   Mesentery                               | +        +        +  +     +           +     +     +  +                  |  17        |
      Lymphoma Malignant                   | X                                                                        |          1 |
                                           |__________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Lymphoma Malignant                   |                                                                          |          4 |
                                           |__________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Lymphoma Malignant                   |                                                                          |          4 |
                                           |__________________________________________________________________________|____________|
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page   7                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 6| 7| 7| 5| 7| 7| 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 6| 7| 6|  |            |
                             DAY ON TEST   | 3| 3| 3| 3| 0| 1| 3| 3| 9| 3| 3| 3| 3| 5| 3| 3| 3| 3| 3| 3| 3| 1| 3| 5|  |            |
                                           | 7| 7| 5| 6| 0| 0| 7| 7| 9| 5| 6| 6| 6| 9| 7| 6| 7| 5| 6| 5| 7| 6| 6| 9|  |            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|  |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|  |     T      |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|  |     A      |
    CONTROL                                | 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|  |     L      |
                                           | 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|  |            |
 _____________________________________________________________________________________________________________________|____________|
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Lymphoma Malignant                   |                                                                          |          3 |
                                           |__________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  48        |
      Lymphoma Malignant                   | X                                                                        |          2 |
                                           |__________________________________________________________________________|____________|
   Tongue                                  |                                                                      +   |   1        |
      Squamous Cell Carcinoma              |                                                                      X   |          1 |
                                           |__________________________________________________________________________|____________|
   Tooth                                   |                                  +              +                        |   4        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Lymphoma Malignant                   |                                        X                                 |          2 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Adrenal Cortex                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Lymphoma Malignant                   |                                                                          |          1 |
      Subcapsular, Adenoma                 |                                                 X                        |          1 |
                                           |__________________________________________________________________________|____________|
   Adrenal Medulla                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  48        |
      Pheochromocytoma Benign              |                                                       X                  |          2 |
                                           |__________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Adenoma                              |                                        X                                 |          1 |
                                           |__________________________________________________________________________|____________|
   Parathyroid Gland                       | +  M  +  +  I  +  +  +  M  I  +  M  +  +  M  +  +  +  +  +  +  +  M  M   |  37        |
                                           |__________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Lymphoma Malignant                   |                                        X                                 |          1 |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page   8                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 6| 7| 7| 5| 7| 7| 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 6| 7| 6|  |            |
                             DAY ON TEST   | 3| 3| 3| 3| 0| 1| 3| 3| 9| 3| 3| 3| 3| 5| 3| 3| 3| 3| 3| 3| 3| 1| 3| 5|  |            |
                                           | 7| 7| 5| 6| 0| 0| 7| 7| 9| 5| 6| 6| 6| 9| 7| 6| 7| 5| 6| 5| 7| 6| 6| 9|  |            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|  |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|  |     T      |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|  |     A      |
    CONTROL                                | 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|  |     L      |
                                           | 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|  |            |
 _____________________________________________________________________________________________________________________|____________|
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
      Pars Distalis, Adenoma               |                   X           X  X  X  X        X                 X  X   |         13 |
      Pars Intermedia, Adenoma             |                   X                                                      |          1 |
                                           |__________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Follicular Cell, Adenoma             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Clitoral Gland                          | +  +  M  +  I  +  M  +  +  +  +  +  M  +  +  +  I  +  +  +  +  +  +  +   |  40        |
                                           |__________________________________________________________________________|____________|
   Ovary                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Cystadenoma                          |                                                                          |          1 |
      Granulosa Cell Tumor Benign          |                                                    X                     |          1 |
      Hemangioma                           |                                                                          |          1 |
      Luteoma                              |                                                                          |          1 |
      Lymphoma Malignant                   | X                                                                        |          5 |
                                           |__________________________________________________________________________|____________|
   Uterus                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Carcinoma                            |    X                                                                     |          1 |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Lymphoma Malignant                   |                                                                          |          3 |
                                           |__________________________________________________________________________|____________|
   Lymph Node                              |                         +                                                |   5        |
      Iliac, Lymphoma Malignant            |                                                                          |          3 |
      Lumbar, Lymphoma Malignant           |                                                                          |          1 |
      Pancreatic, Lymphoma Malignant       |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page   9                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 6| 7| 7| 5| 7| 7| 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 6| 7| 6|  |            |
                             DAY ON TEST   | 3| 3| 3| 3| 0| 1| 3| 3| 9| 3| 3| 3| 3| 5| 3| 3| 3| 3| 3| 3| 3| 1| 3| 5|  |            |
                                           | 7| 7| 5| 6| 0| 0| 7| 7| 9| 5| 6| 6| 6| 9| 7| 6| 7| 5| 6| 5| 7| 6| 6| 9|  |            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|  |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|  |     T      |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|  |     A      |
    CONTROL                                | 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|  |     L      |
                                           | 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|  |            |
 _____________________________________________________________________________________________________________________|____________|
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
      Renal, Lymphoma Malignant            |                                                                          |          4 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Bronchial                   | +  +  +  +  +  +  M  +  +  +  +  +  +  M  +  +  +  M  +  +  +  +  M  +   |  41        |
      Lymphoma Malignant                   | X                                         X                              |          7 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mandibular                  | +  +  M  +  M  +  +  M  +  M  +  M  +  +  M  +  +  +  M  +  +  +  +  M   |  36        |
      Lymphoma Malignant                   | X                                      X                                 |          8 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  I  +   |  47        |
      Lymphoma Malignant                   | X                                      X  X                              |          9 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mediastinal                 | +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  M  +  +  +  +  +  +   |  43        |
      Lymphoma Malignant                   | X                                      X  X                              |          9 |
                                           |__________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Hemangiosarcoma                      |                                                                          |          1 |
      Lymphoma Malignant                   | X                    X                 X  X                              |         11 |
                                           |__________________________________________________________________________|____________|
   Thymus                                  | +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  48        |
      Lymphoma Malignant                   |                                        X  X                              |          8 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Mammary Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  48        |
      Carcinoma                            |                                                                      X   |          1 |
                                           |__________________________________________________________________________|____________|
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Subcutaneous Tissue, Sarcoma         |                                                                          |          2 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  10                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 6| 7| 7| 5| 7| 7| 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 6| 7| 6|  |            |
                             DAY ON TEST   | 3| 3| 3| 3| 0| 1| 3| 3| 9| 3| 3| 3| 3| 5| 3| 3| 3| 3| 3| 3| 3| 1| 3| 5|  |            |
                                           | 7| 7| 5| 6| 0| 0| 7| 7| 9| 5| 6| 6| 6| 9| 7| 6| 7| 5| 6| 5| 7| 6| 6| 9|  |            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|  |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|  |     T      |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|  |     A      |
    CONTROL                                | 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|  |     L      |
                                           | 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|  |            |
 _____________________________________________________________________________________________________________________|____________|
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
                                           |__________________________________________________________________________|____________|
   Peripheral Nerve                        |                                                          +               |   1        |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Larynx                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Lymphoma Malignant                   |                                        X                                 |          2 |
                                           |__________________________________________________________________________|____________|
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Alveolar/Bronchiolar Adenoma         |                                           X                              |          1 |
      Alveolar/Bronchiolar Carcinoma       |             X  X                                                         |          6 |
      Hepatocellular Carcinoma, Metastatic,|                                                                          |            |
           Liver                           |    X                                                                     |          2 |
      Lymphoma Malignant                   | X                                      X                                 |          9 |
      Mediastinum, Alveolar/Bronchiolar    |                                                                          |            |
          Carcinoma, Metastatic, Lung      |             X                                                            |          1 |
                                           |__________________________________________________________________________|____________|
   Nose                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Pleura                                  |                            +                                             |   1        |
                                           |__________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Ear                                     |                                                                          |   1        |
                                           |__________________________________________________________________________|____________|
   Eye                                     |       +                                                                  |   2        |
                                           |__________________________________________________________________________|____________|
   Harderian Gland                         |       +                                                                  |   4        |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  11                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 6| 7| 7| 5| 7| 7| 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 6| 7| 6|  |            |
                             DAY ON TEST   | 3| 3| 3| 3| 0| 1| 3| 3| 9| 3| 3| 3| 3| 5| 3| 3| 3| 3| 3| 3| 3| 1| 3| 5|  |            |
                                           | 7| 7| 5| 6| 0| 0| 7| 7| 9| 5| 6| 6| 6| 9| 7| 6| 7| 5| 6| 5| 7| 6| 6| 9|  |            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|  |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|  |     T      |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|  |     A      |
    CONTROL                                | 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|  |     L      |
                                           | 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|  |            |
 _____________________________________________________________________________________________________________________|____________|
 SPECIAL SENSES SYSTEM - cont              |                                                                          |            |
                                           |                                                                          |            |
      Adenoma                              |       X                                                                  |          3 |
      Carcinoma                            |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |            |
          Metastatic, Lung                 |             X                                                            |          1 |
      Lymphoma Malignant                   |                                           X                              |          5 |
                                           |__________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Lymphoma Malignant                   | X                                                                        |          6 |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +   |  49        |
      Lymphoma Malignant                   | X                    X                 X  X                              |         11 |
 __________________________________________________________________________________________________________________________________ 
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  12                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 5| 7| 7| 7| 6| 6| 7| 7| 7| 6| 6| 7| 6|             
                             DAY ON TEST   | 3| 9| 2| 3| 3| 3| 3| 3| 9| 3| 3| 3| 8| 3| 3| 3| 5| 4| 3| 3| 3| 5| 0| 3| 1|             
                                           | 6| 2| 8| 7| 7| 6| 6| 3| 2| 5| 1| 5| 8| 7| 7| 6| 8| 4| 6| 7| 6| 8| 1| 7| 6|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    25 PPM                                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |__________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |             
           Liver                           |    X                                                                     |             
                                           |__________________________________________________________________________|             
   Gallbladder                             | +  +  +  +  +  +  +  A  A  I  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |             
           Liver                           |    X                                                                     |             
                                           |__________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  I  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  A  A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  A  A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |             
           Liver                           |    X                                                                     |             
                                           |__________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hepatocellular Carcinoma             |       X  X           X     X                       X           X        X|             
      Hepatocellular Carcinoma, Multiple   |                                                                          |             
      Hepatocellular Adenoma               |       X     X                    X           X                    X  X   |             
      Hepatocellular Adenoma, Multiple     |                                                                          |             
      Hepatocholangiocarcinoma             |    X                                                                     |             
      Lymphoma Malignant                   |                               X     X                                    |             
      Sarcoma, Metastatic, Skin            |       X                                                                  |             
                                           |__________________________________________________________________________|             
   Mesentery                               |    +  +                          +  +  +     +  +     +  +               |             
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |             
           Liver                           |    X                                                                     |             
      Lymphoma Malignant                   |                                                                          |             
      Sarcoma, Metastatic, Skin            |       X                                                                  |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  13                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 5| 7| 7| 7| 6| 6| 7| 7| 7| 6| 6| 7| 6|             
                             DAY ON TEST   | 3| 9| 2| 3| 3| 3| 3| 3| 9| 3| 3| 3| 8| 3| 3| 3| 5| 4| 3| 3| 3| 5| 0| 3| 1|             
                                           | 6| 2| 8| 7| 7| 6| 6| 3| 2| 5| 1| 5| 8| 7| 7| 6| 8| 4| 6| 7| 6| 8| 1| 7| 6|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    25 PPM                                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
                                           |__________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |             
           Liver                           |    X                                                                     |             
      Lymphoma Malignant                   |                X              X                                          |             
                                           |__________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                                                         X|             
                                           |__________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |             
           Liver                           |    X                                                                     |             
      Squamous Cell Carcinoma              |                                                 X                        |             
                                           |__________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +|             
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |             
           Liver                           |    X                                                                     |             
                                           |__________________________________________________________________________|             
   Tooth                                   |                      +                                                   |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |__________________________________________________________________________|             
   Adrenal Cortex                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Adrenal Medulla                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Parathyroid Gland                       | +  +  M  +  M  +  M  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Pars Distalis, Adenoma               | X                 X           X                       X              X   |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  14                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 5| 7| 7| 7| 6| 6| 7| 7| 7| 6| 6| 7| 6|             
                             DAY ON TEST   | 3| 9| 2| 3| 3| 3| 3| 3| 9| 3| 3| 3| 8| 3| 3| 3| 5| 4| 3| 3| 3| 5| 0| 3| 1|             
                                           | 6| 2| 8| 7| 7| 6| 6| 3| 2| 5| 1| 5| 8| 7| 7| 6| 8| 4| 6| 7| 6| 8| 1| 7| 6|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    25 PPM                                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
      Pars Intermedia, Adenoma             |                               X                                          |             
                                           |__________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Clitoral Gland                          | +  +  +  +  +  I  +  M  +  +  +  +  +  +  +  +  +  +  +  +  M  M  M  +  +|             
                                           |__________________________________________________________________________|             
   Ovary                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Carcinoma, Metastatic, Uterus        |                                                                          |             
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |             
           Liver                           |    X                                                                     |             
      Lymphoma Malignant                   |                                                                         X|             
                                           |__________________________________________________________________________|             
   Uterus                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Carcinoma                            |                                                                          |             
      Hemangiosarcoma                      | X                                                                        |             
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |             
           Liver                           |    X                                                                     |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |__________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                               X                                          |             
                                           |__________________________________________________________________________|             
   Lymph Node                              |                               +                                          |             
      Iliac, Lymphoma Malignant            |                                                                          |             
      Lumbar, Lymphoma Malignant           |                               X                                          |             
      Pancreatic, Lymphoma Malignant       |                                                                          |             
      Renal, Lymphoma Malignant            |                               X                                          |             
                                           |__________________________________________________________________________|             
   Lymph Node, Bronchial                   | +  +  +  +  +  +  +  +  +  +  M  +  M  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  15                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 5| 7| 7| 7| 6| 6| 7| 7| 7| 6| 6| 7| 6|             
                             DAY ON TEST   | 3| 9| 2| 3| 3| 3| 3| 3| 9| 3| 3| 3| 8| 3| 3| 3| 5| 4| 3| 3| 3| 5| 0| 3| 1|             
                                           | 6| 2| 8| 7| 7| 6| 6| 3| 2| 5| 1| 5| 8| 7| 7| 6| 8| 4| 6| 7| 6| 8| 1| 7| 6|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    25 PPM                                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
           Liver                           |    X                                                                     |             
      Lymphoma Malignant                   |                X                                                        X|             
                                           |__________________________________________________________________________|             
   Lymph Node, Mandibular                  | +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  M  +  M  M  +  +  M  +|             
      Lymphoma Malignant                   |                               X     X                                   X|             
                                           |__________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +|             
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |             
           Liver                           |    X                                                                     |             
      Lymphoma Malignant                   |                X              X     X                                   X|             
                                           |__________________________________________________________________________|             
   Lymph Node, Mediastinal                 | +  +  +  +  +  +  M  +  +  +  +  M  +  +  +  +  +  M  +  +  +  +  +  M  +|             
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |             
           Liver                           |    X                                                                     |             
      Lymphoma Malignant                   |                               X     X                                   X|             
                                           |__________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hemangiosarcoma                      |                                                                          |             
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |             
           Liver                           |    X                                                                     |             
      Lymphoma Malignant                   |             X  X              X     X                                   X|             
                                           |__________________________________________________________________________|             
   Thymus                                  | +  M  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |             X                 X     X                                   X|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |__________________________________________________________________________|             
   Mammary Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Carcinoma                            |                                                                      X   |             
                                           |__________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Basal Cell Carcinoma                 |          X                                                               |             
      Subcutaneous Tissue, Fibrous         |                                                                          |             
          Histiocytoma                     |                                                    X                     |             
      Subcutaneous Tissue, Hemangiosarcoma |                                                                          |             
      Subcutaneous Tissue, Sarcoma         |       X                             X                                    |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  16                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 5| 7| 7| 7| 6| 6| 7| 7| 7| 6| 6| 7| 6|             
                             DAY ON TEST   | 3| 9| 2| 3| 3| 3| 3| 3| 9| 3| 3| 3| 8| 3| 3| 3| 5| 4| 3| 3| 3| 5| 0| 3| 1|             
                                           | 6| 2| 8| 7| 7| 6| 6| 3| 2| 5| 1| 5| 8| 7| 7| 6| 8| 4| 6| 7| 6| 8| 1| 7| 6|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    25 PPM                                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |__________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Osteoma                              |                                  X                                       |             
                                           |__________________________________________________________________________|             
   Skeletal Muscle                         |    +                                                                     |             
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |             
           Liver                           |    X                                                                     |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                                                         X|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |__________________________________________________________________________|             
   Larynx                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Alveolar/Bronchiolar Adenoma         |                                                                         X|             
      Alveolar/Bronchiolar Carcinoma       |                            X                                             |             
      Carcinoma, Metastatic, Uterus        |                                                                          |             
      Hemangiosarcoma, Metastatic, Skin    |                                                                          |             
      Hepatocellular Carcinoma, Metastatic,|                                                                          |             
           Liver                           |                            X                                             |             
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |             
           Liver                           |    X                                                                     |             
      Lymphoma Malignant                   |                               X                                         X|             
      Mediastinum, Sarcoma, Metastatic,    |                                                                          |             
           Skin                            |       X                                                                  |             
                                           |__________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Eye                                     |                                     +                                    |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  17                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 5| 7| 7| 7| 6| 6| 7| 7| 7| 6| 6| 7| 6|             
                             DAY ON TEST   | 3| 9| 2| 3| 3| 3| 3| 3| 9| 3| 3| 3| 8| 3| 3| 3| 5| 4| 3| 3| 3| 5| 0| 3| 1|             
                                           | 6| 2| 8| 7| 7| 6| 6| 3| 2| 5| 1| 5| 8| 7| 7| 6| 8| 4| 6| 7| 6| 8| 1| 7| 6|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    25 PPM                                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 SPECIAL SENSES SYSTEM - cont              |                                                                          |             
                                           |                                                                          |             
                                           |__________________________________________________________________________|             
   Harderian Gland                         | +                                   +           +                        |             
      Adenoma                              | X                                   X           X                        |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |             
           Liver                           |    X                                                                     |             
      Lymphoma Malignant                   |                               X                                          |             
                                           |__________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                               X                                         X|             
 __________________________________________|__________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |             X  X              X     X                                   X|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  18                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 4| 7| 7| 5| 7| 7| 6| 7| 7| 7| 7| 7| 7| 3| 5| 5| 7| 7| 7| 7| 6| 7| 5|            |
                             DAY ON TEST   | 3| 1| 8| 0| 2| 3| 3| 3| 2| 3| 3| 3| 3| 3| 3| 0| 2| 7| 3| 3| 3| 3| 7| 3| 8|            |
                                           | 6| 4| 8| 0| 2| 2| 7| 6| 4| 6| 6| 7| 7| 7| 6| 5| 7| 1| 6| 5| 7| 7| 3| 7| 8|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|     A      |
    25 PPM                                 | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Gallbladder                             | +  +  A  +  I  +  +  +  +  +  I  +  +  +  +  A  +  A  +  +  +  +  A  +  +|  40        |
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +|  47        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  A  +  A  +  +  +  +  A  +  +|  43        |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  A  +  A  +  +  +  +  A  +  +|  43        |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  A  +  A  +  +  +  +  A  +  +|  45        |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  A  +  A  +  +  +  +  A  +  +|  45        |
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Hepatocellular Carcinoma             |       X  X        X  X  X              X                          X  X   |         15 |
      Hepatocellular Carcinoma, Multiple   |                                                             X            |          1 |
      Hepatocellular Adenoma               | X              X                          X              X           X   |         11 |
      Hepatocellular Adenoma, Multiple     |    X                                                           X         |          2 |
      Hepatocholangiocarcinoma             |                                                                          |          1 |
      Lymphoma Malignant                   |                                                       X                 X|          4 |
      Sarcoma, Metastatic, Skin            |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Mesentery                               |             +  +     +           +        +              +  +  +     +   |  18        |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  19                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 4| 7| 7| 5| 7| 7| 6| 7| 7| 7| 7| 7| 7| 3| 5| 5| 7| 7| 7| 7| 6| 7| 5|            |
                             DAY ON TEST   | 3| 1| 8| 0| 2| 3| 3| 3| 2| 3| 3| 3| 3| 3| 3| 0| 2| 7| 3| 3| 3| 3| 7| 3| 8|            |
                                           | 6| 4| 8| 0| 2| 2| 7| 6| 4| 6| 6| 7| 7| 7| 6| 5| 7| 1| 6| 5| 7| 7| 3| 7| 8|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|     A      |
    25 PPM                                 | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
      Lymphoma Malignant                   |                                                             X            |          1 |
      Sarcoma, Metastatic, Skin            |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Pancreas                                | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +|  47        |
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
      Lymphoma Malignant                   |                                                                         X|          3 |
                                           |__________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
      Squamous Cell Carcinoma              |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +|  47        |
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Tooth                                   |                                           +                              |   2        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Adrenal Cortex                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  20                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 4| 7| 7| 5| 7| 7| 6| 7| 7| 7| 7| 7| 7| 3| 5| 5| 7| 7| 7| 7| 6| 7| 5|            |
                             DAY ON TEST   | 3| 1| 8| 0| 2| 3| 3| 3| 2| 3| 3| 3| 3| 3| 3| 0| 2| 7| 3| 3| 3| 3| 7| 3| 8|            |
                                           | 6| 4| 8| 0| 2| 2| 7| 6| 4| 6| 6| 7| 7| 7| 6| 5| 7| 1| 6| 5| 7| 7| 3| 7| 8|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|     A      |
    25 PPM                                 | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
   Adrenal Medulla                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +|  47        |
                                           |__________________________________________________________________________|____________|
   Parathyroid Gland                       | +  +  M  M  M  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  M  +  +  M  +|  40        |
                                           |__________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Pars Distalis, Adenoma               |                X        X                                               X|          8 |
      Pars Intermedia, Adenoma             |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Clitoral Gland                          | +  +  +  +  +  +  M  +  +  +  M  +  M  +  +  +  +  +  +  +  +  +  +  +  +|  42        |
                                           |__________________________________________________________________________|____________|
   Ovary                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  I  +  +  +|  49        |
      Carcinoma, Metastatic, Uterus        |             X                                                            |          1 |
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
      Lymphoma Malignant                   |                                                                         X|          2 |
                                           |__________________________________________________________________________|____________|
   Uterus                                  | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Carcinoma                            |             X                                                            |          1 |
      Hemangiosarcoma                      |                                                                          |          1 |
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  21                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 4| 7| 7| 5| 7| 7| 6| 7| 7| 7| 7| 7| 7| 3| 5| 5| 7| 7| 7| 7| 6| 7| 5|            |
                             DAY ON TEST   | 3| 1| 8| 0| 2| 3| 3| 3| 2| 3| 3| 3| 3| 3| 3| 0| 2| 7| 3| 3| 3| 3| 7| 3| 8|            |
                                           | 6| 4| 8| 0| 2| 2| 7| 6| 4| 6| 6| 7| 7| 7| 6| 5| 7| 1| 6| 5| 7| 7| 3| 7| 8|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|     A      |
    25 PPM                                 | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                                       X                  |          2 |
                                           |__________________________________________________________________________|____________|
   Lymph Node                              |                                                                         +|   2        |
      Iliac, Lymphoma Malignant            |                                                                         X|          1 |
      Lumbar, Lymphoma Malignant           |                                                                          |          1 |
      Pancreatic, Lymphoma Malignant       |                                                                         X|          1 |
      Renal, Lymphoma Malignant            |                                                                         X|          2 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Bronchial                   | M  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +|  45        |
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
      Lymphoma Malignant                   |                                                       X                 X|          4 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mandibular                  | +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  M  M  +  +  +  M  +  M  +|  40        |
      Lymphoma Malignant                   |                                                       X                 X|          5 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +|  47        |
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
      Lymphoma Malignant                   |                                                       X     X           X|          7 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mediastinal                 | +  +  +  +  +  +  +  M  +  +  +  +  +  M  +  +  +  M  +  +  M  +  +  +  +|  42        |
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
      Lymphoma Malignant                   |                                                       X                 X|          5 |
                                           |__________________________________________________________________________|____________|
   Spleen                                  | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +|  47        |
      Hemangiosarcoma                      |          X                                                               |          1 |
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  22                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 4| 7| 7| 5| 7| 7| 6| 7| 7| 7| 7| 7| 7| 3| 5| 5| 7| 7| 7| 7| 6| 7| 5|            |
                             DAY ON TEST   | 3| 1| 8| 0| 2| 3| 3| 3| 2| 3| 3| 3| 3| 3| 3| 0| 2| 7| 3| 3| 3| 3| 7| 3| 8|            |
                                           | 6| 4| 8| 0| 2| 2| 7| 6| 4| 6| 6| 7| 7| 7| 6| 5| 7| 1| 6| 5| 7| 7| 3| 7| 8|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|     A      |
    25 PPM                                 | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
      Lymphoma Malignant                   |                                                       X     X           X|          8 |
                                           |__________________________________________________________________________|____________|
   Thymus                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
      Lymphoma Malignant                   |                                                       X                 X|          6 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Mammary Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Carcinoma                            |                X                                                         |          2 |
                                           |__________________________________________________________________________|____________|
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Basal Cell Carcinoma                 |                                                                          |          1 |
      Subcutaneous Tissue, Fibrous         |                                                                          |            |
          Histiocytoma                     |                                                                          |          1 |
      Subcutaneous Tissue, Hemangiosarcoma |          X                                                               |          1 |
      Subcutaneous Tissue, Sarcoma         |                                                                          |          2 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Osteoma                              |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Skeletal Muscle                         |             +                                                            |   2        |
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  23                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 4| 7| 7| 5| 7| 7| 6| 7| 7| 7| 7| 7| 7| 3| 5| 5| 7| 7| 7| 7| 6| 7| 5|            |
                             DAY ON TEST   | 3| 1| 8| 0| 2| 3| 3| 3| 2| 3| 3| 3| 3| 3| 3| 0| 2| 7| 3| 3| 3| 3| 7| 3| 8|            |
                                           | 6| 4| 8| 0| 2| 2| 7| 6| 4| 6| 6| 7| 7| 7| 6| 5| 7| 1| 6| 5| 7| 7| 3| 7| 8|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|     A      |
    25 PPM                                 | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 RESPIRATORY SYSTEM - cont                 |                                                                          |            |
                                           |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Larynx                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Alveolar/Bronchiolar Adenoma         |                            X        X  X                                 |          4 |
      Alveolar/Bronchiolar Carcinoma       |                   X                                         X            |          3 |
      Carcinoma, Metastatic, Uterus        |             X                                                            |          1 |
      Hemangiosarcoma, Metastatic, Skin    |          X                                                               |          1 |
      Hepatocellular Carcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
      Lymphoma Malignant                   |                                                       X                 X|          4 |
      Mediastinum, Sarcoma, Metastatic,    |                                                                          |            |
           Skin                            |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Nose                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Eye                                     |                                                                          |   1        |
                                           |__________________________________________________________________________|____________|
   Harderian Gland                         |                                        +                                 |   4        |
      Adenoma                              |                                        X                                 |          4 |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Hepatocholangiocarcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  24                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 4| 7| 7| 5| 7| 7| 6| 7| 7| 7| 7| 7| 7| 3| 5| 5| 7| 7| 7| 7| 6| 7| 5|            |
                             DAY ON TEST   | 3| 1| 8| 0| 2| 3| 3| 3| 2| 3| 3| 3| 3| 3| 3| 0| 2| 7| 3| 3| 3| 3| 7| 3| 8|            |
                                           | 6| 4| 8| 0| 2| 2| 7| 6| 4| 6| 6| 7| 7| 7| 6| 5| 7| 1| 6| 5| 7| 7| 3| 7| 8|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|     A      |
    25 PPM                                 | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 URINARY SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
      Lymphoma Malignant                   |                                                             X           X|          3 |
                                           |__________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  A  +  A  +  +  +  +  +  +  +|  46        |
      Lymphoma Malignant                   |                                                                          |          2 |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                                       X     X           X|          8 |
 __________________________________________________________________________________________________________________________________ 
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  25                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 0| 5| 7| 7| 7| 6| 6| 7| 7| 7|             
                             DAY ON TEST   | 1| 5| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 0| 1| 3| 3| 0| 7| 5| 3| 3| 0|             
                                           | 4| 2| 6| 6| 6| 6| 6| 5| 6| 6| 6| 5| 7| 7| 6| 3| 1| 6| 6| 0| 2| 2| 7| 5| 0|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    100 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |__________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Gallbladder                             | +  M  +  +  +  +  +  +  I  +  M  +  +  I  +  M  +  +  +  +  +  M  +  +  +|             
      Lymphoma Malignant                   |                                  X                                       |             
      Mast Cell Tumor Malignant,           |                                                                          |             
          Metastatic, Uncertain Primary    |                                                                          |             
          Site                             |                                                          X               |             
                                           |__________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hepatocellular Carcinoma             |                                           X                    X         |             
      Hepatocellular Adenoma               |    X                                                                     |             
      Hepatocellular Adenoma, Multiple     | X                                                                        |             
      Lymphoma Malignant                   |                            X     X                                       |             
      Mast Cell Tumor Malignant,           |                                                                          |             
          Metastatic, Uncertain Primary    |                                                                          |             
          Site                             |                                                          X               |             
                                           |__________________________________________________________________________|             
   Mesentery                               |                   +  +                 +        +     +              +   |             
      Lymphoma Malignant                   |                                                                          |             
                                           |__________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                  X                                       |             
                                           |__________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  26                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 0| 5| 7| 7| 7| 6| 6| 7| 7| 7|             
                             DAY ON TEST   | 1| 5| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 0| 1| 3| 3| 0| 7| 5| 3| 3| 0|             
                                           | 4| 2| 6| 6| 6| 6| 6| 5| 6| 6| 6| 5| 7| 7| 6| 3| 1| 6| 6| 0| 2| 2| 7| 5| 0|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    100 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
      Lymphoma Malignant                   |                            X     X                                       |             
                                           |__________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Mast Cell Tumor Malignant,           |                                                                          |             
          Metastatic, Uncertain Primary    |                                                                          |             
          Site                             |                                                          X               |             
                                           |__________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                  X                                       |             
      Mast Cell Tumor Malignant,           |                                                                          |             
          Metastatic, Uncertain Primary    |                                                                          |             
          Site                             |                                                          X               |             
                                           |__________________________________________________________________________|             
   Tooth                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Blood Vessel                            |                                                          +               |             
      Aorta, Mast Cell Tumor Malignant,    |                                                                          |             
           Metastatic, Uncertain Primary   |                                                                          |             
          Site                             |                                                          X               |             
                                           |__________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |__________________________________________________________________________|             
   Adrenal Cortex                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                                                          |             
                                           |__________________________________________________________________________|             
   Adrenal Medulla                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Pheochromocytoma Benign              |                   X                                                      |             
                                           |__________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Adenoma                              | X                                                                        |             
                                           |__________________________________________________________________________|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  27                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 0| 5| 7| 7| 7| 6| 6| 7| 7| 7|             
                             DAY ON TEST   | 1| 5| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 0| 1| 3| 3| 0| 7| 5| 3| 3| 0|             
                                           | 4| 2| 6| 6| 6| 6| 6| 5| 6| 6| 6| 5| 7| 7| 6| 3| 1| 6| 6| 0| 2| 2| 7| 5| 0|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    100 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
   Parathyroid Gland                       | M  +  +  I  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M|             
                                           |__________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  I  +  +  +  +  +  +|             
      Mast Cell Tumor Malignant,           |                                                                          |             
          Metastatic, Uncertain Primary    |                                                                          |             
          Site                             |                                                          X               |             
      Pars Distalis, Adenoma               |       X  X     X              X        X  X     X                       X|             
      Pars Intermedia, Adenoma             |                                                                X         |             
                                           |__________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Clitoral Gland                          | +  +  +  +  +  +  +  +  M  M  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Ovary                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  I  +  +  +|             
      Cystadenoma                          |                   X                                               X      |             
      Granulosa Cell Tumor Benign          |                                                       X                  |             
      Granulosa-Theca Tumor Malignant      |                                     X                                    |             
      Hemangiosarcoma                      |                                                                          |             
      Lymphoma Malignant                   |                                                                          |             
      Mast Cell Tumor Malignant,           |                                                                          |             
          Metastatic, Uncertain Primary    |                                                                          |             
          Site                             |                                                          X               |             
      Tubulostromal Adenoma                |                            X                                             |             
                                           |__________________________________________________________________________|             
   Uterus                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                  X                                       |             
      Mast Cell Tumor Malignant,           |                                                                          |             
          Metastatic, Uncertain Primary    |                                                                          |             
          Site                             |                                                          X               |             
      Polyp Stromal                        | X                                                                        |             
 _____________________________________________________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  28                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 0| 5| 7| 7| 7| 6| 6| 7| 7| 7|             
                             DAY ON TEST   | 1| 5| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 0| 1| 3| 3| 0| 7| 5| 3| 3| 0|             
                                           | 4| 2| 6| 6| 6| 6| 6| 5| 6| 6| 6| 5| 7| 7| 6| 3| 1| 6| 6| 0| 2| 2| 7| 5| 0|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    100 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |__________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hemangiosarcoma                      |                               X                                          |             
      Lymphoma Malignant                   |                                                                          |             
                                           |__________________________________________________________________________|             
   Lymph Node                              |                                                          +               |             
      Mast Cell Tumor Malignant,           |                                                                          |             
          Metastatic, Uncertain Primary    |                                                                          |             
          Site                             |                                                          X               |             
      Iliac, Lymphoma Malignant            |                                                                          |             
      Iliac, Mast Cell Tumor Malignant,    |                                                                          |             
           Metastatic, Uncertain Primary   |                                                                          |             
          Site                             |                                                          X               |             
      Lumbar, Lymphoma Malignant           |                                                                          |             
      Pancreatic, Lymphoma Malignant       |                                                                          |             
      Renal, Lymphoma Malignant            |                                                                          |             
                                           |__________________________________________________________________________|             
   Lymph Node, Bronchial                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M|             
      Lymphoma Malignant                   |                            X     X     X              X                  |             
      Mast Cell Tumor Malignant,           |                                                                          |             
          Metastatic, Uncertain Primary    |                                                                          |             
          Site                             |                                                          X               |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mandibular                  | M  M  +  M  M  +  +  +  +  M  M  +  +  +  +  +  +  I  +  +  +  +  +  +  +|             
      Carcinoma, Metastatic, Harderian     |                                                                          |             
          Gland                            |                                                                          |             
      Lymphoma Malignant                   |                                  X     X              X                  |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                  X     X              X                  |             
      Mast Cell Tumor Malignant,           |                                                                          |             
          Metastatic, Uncertain Primary    |                                                                          |             
          Site                             |                                                          X               |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mediastinal                 | +  +  +  M  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  M  +  M|             
      Lymphoma Malignant                   |                            X     X     X              X                  |             
      Mast Cell Tumor Malignant,           |                                                                          |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  29                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 0| 5| 7| 7| 7| 6| 6| 7| 7| 7|             
                             DAY ON TEST   | 1| 5| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 0| 1| 3| 3| 0| 7| 5| 3| 3| 0|             
                                           | 4| 2| 6| 6| 6| 6| 6| 5| 6| 6| 6| 5| 7| 7| 6| 3| 1| 6| 6| 0| 2| 2| 7| 5| 0|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    100 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
          Metastatic, Uncertain Primary    |                                                                          |             
          Site                             |                                                          X               |             
                                           |__________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hemangiosarcoma                      |                                                                         X|             
      Lymphoma Malignant                   |                            X        X  X              X                  |             
                                           |__________________________________________________________________________|             
   Thymus                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                            X                                             |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |__________________________________________________________________________|             
   Mammary Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Carcinoma                            |                                                                         X|             
                                           |__________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Neural Crest Tumor                   |                                  X                                       |             
      Squamous Cell Papilloma              |                                                                          |             
      Subcutaneous Tissue, Fibrosarcoma    |                                                                          |             
      Subcutaneous Tissue, Sarcoma         |                                                                          |             
      Subcutaneous Tissue, Schwannoma      |                                                                          |             
          Malignant                        |                                                                      X   |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |__________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Carcinoma, Metastatic, Uncertain     |                                                                          |             
          Primary Site                     |                                  X                                       |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Mast Cell Tumor Malignant,           |                                                                          |             
          Metastatic, Uncertain Primary    |                                                                          |             
          Site                             |                                                          X               |             
 _____________________________________________________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  30                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 0| 5| 7| 7| 7| 6| 6| 7| 7| 7|             
                             DAY ON TEST   | 1| 5| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 0| 1| 3| 3| 0| 7| 5| 3| 3| 0|             
                                           | 4| 2| 6| 6| 6| 6| 6| 5| 6| 6| 6| 5| 7| 7| 6| 3| 1| 6| 6| 0| 2| 2| 7| 5| 0|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    100 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |__________________________________________________________________________|             
   Larynx                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Alveolar/Bronchiolar Carcinoma       |                                                             X            |             
      Carcinoma, Metastatic, Harderian     |                                                                          |             
          Gland                            |                                                                          |             
      Hepatocellular Carcinoma, Metastatic,|                                                                          |             
           Liver                           |                                                                X         |             
      Lymphoma Malignant                   |                            X     X     X                                 |             
      Mast Cell Tumor Malignant,           |                                                                          |             
          Metastatic, Uncertain Primary    |                                                                          |             
          Site                             |                                                          X               |             
                                           |__________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                                                          |             
      Mast Cell Tumor Malignant,           |                                                                          |             
          Metastatic, Uncertain Primary    |                                                                          |             
          Site                             |                                                          X               |             
                                           |__________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Ear                                     |                                                             +            |             
                                           |__________________________________________________________________________|             
   Eye                                     |                   +              +                                       |             
      Carcinoma, Metastatic, Uncertain     |                                                                          |             
          Primary Site                     |                                  X                                       |             
                                           |__________________________________________________________________________|             
   Harderian Gland                         |                   +                                                      |             
      Adenoma                              |                                                                          |             
      Carcinoma                            |                   X                                                      |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  31                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 0| 5| 7| 7| 7| 6| 6| 7| 7| 7|             
                             DAY ON TEST   | 1| 5| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 0| 1| 3| 3| 0| 7| 5| 3| 3| 0|             
                                           | 4| 2| 6| 6| 6| 6| 6| 5| 6| 6| 6| 5| 7| 7| 6| 3| 1| 6| 6| 0| 2| 2| 7| 5| 0|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    100 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 URINARY SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Lymphoma Malignant                   |                                                                          |             
      Mast Cell Tumor Malignant,           |                                                                          |             
          Metastatic, Uncertain Primary    |                                                                          |             
          Site                             |                                                          X               |             
                                           |__________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                                                          |             
 __________________________________________|__________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                            X     X  X  X              X                  |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  32                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 3| 6| 7| 7| 7| 5|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 1| 3| 3| 3| 1| 3| 3| 3| 5| 8| 2| 3| 3| 9|            |
                                           | 5| 7| 6| 7| 6| 5| 7| 5| 7| 6| 6| 0| 7| 4| 7| 2| 6| 6| 6| 6| 6| 3| 7| 7| 4|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|     A      |
    100 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Gallbladder                             | +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  A  +  +  +  +  +  +  +  M  A|  40        |
      Lymphoma Malignant                   |                                     X                                    |          2 |
      Mast Cell Tumor Malignant,           |                                                                          |            |
          Metastatic, Uncertain Primary    |                                                                          |            |
          Site                             |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  A|  47        |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  A|  47        |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +|  48        |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Hepatocellular Carcinoma             |          X                    X  X                                      X|          6 |
      Hepatocellular Adenoma               | X  X                 X     X              X     X                        |          7 |
      Hepatocellular Adenoma, Multiple     |                                                                          |          1 |
      Lymphoma Malignant                   |                                     X     X  X     X                     |          6 |
      Mast Cell Tumor Malignant,           |                                                                          |            |
          Metastatic, Uncertain Primary    |                                                                          |            |
          Site                             |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Mesentery                               |             +        +              +  +              +           +      |  12        |
      Lymphoma Malignant                   |                                     X                                    |          1 |
                                           |__________________________________________________________________________|____________|
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  33                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 3| 6| 7| 7| 7| 5|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 1| 3| 3| 3| 1| 3| 3| 3| 5| 8| 2| 3| 3| 9|            |
                                           | 5| 7| 6| 7| 6| 5| 7| 5| 7| 6| 6| 0| 7| 4| 7| 2| 6| 6| 6| 6| 6| 3| 7| 7| 4|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|     A      |
    100 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                     X     X  X                           |          4 |
                                           |__________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                     X        X                           |          4 |
                                           |__________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Mast Cell Tumor Malignant,           |                                                                          |            |
          Metastatic, Uncertain Primary    |                                                                          |            |
          Site                             |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                                                          |          1 |
      Mast Cell Tumor Malignant,           |                                                                          |            |
          Metastatic, Uncertain Primary    |                                                                          |            |
          Site                             |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Tooth                                   |    +                                                                     |   1        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Blood Vessel                            |                                              +                           |   2        |
      Aorta, Mast Cell Tumor Malignant,    |                                                                          |            |
           Metastatic, Uncertain Primary   |                                                                          |            |
          Site                             |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                           X                              |          1 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Adrenal Cortex                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  34                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 3| 6| 7| 7| 7| 5|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 1| 3| 3| 3| 1| 3| 3| 3| 5| 8| 2| 3| 3| 9|            |
                                           | 5| 7| 6| 7| 6| 5| 7| 5| 7| 6| 6| 0| 7| 4| 7| 2| 6| 6| 6| 6| 6| 3| 7| 7| 4|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|     A      |
    100 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
      Lymphoma Malignant                   |                                     X        X                           |          2 |
                                           |__________________________________________________________________________|____________|
   Adrenal Medulla                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Pheochromocytoma Benign              |    X                                                                     |          2 |
                                           |__________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Adenoma                              |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Parathyroid Gland                       | +  +  M  +  +  +  +  M  M  +  M  +  +  +  M  +  +  +  +  M  +  I  +  M  +|  38        |
                                           |__________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Mast Cell Tumor Malignant,           |                                                                          |            |
          Metastatic, Uncertain Primary    |                                                                          |            |
          Site                             |                                                                          |          1 |
      Pars Distalis, Adenoma               |                         X                             X                  |         10 |
      Pars Intermedia, Adenoma             |                                                                X         |          2 |
                                           |__________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Clitoral Gland                          | +  +  +  +  +  +  +  +  +  +  +  +  +  I  +  +  +  +  +  +  +  M  +  +  M|  44        |
                                           |__________________________________________________________________________|____________|
   Ovary                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Cystadenoma                          |                                                 X                        |          3 |
      Granulosa Cell Tumor Benign          |                                                                          |          1 |
      Granulosa-Theca Tumor Malignant      |                                                                          |          1 |
      Hemangiosarcoma                      |                            X                                             |          1 |
      Lymphoma Malignant                   |                                     X     X  X                           |          3 |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  35                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 3| 6| 7| 7| 7| 5|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 1| 3| 3| 3| 1| 3| 3| 3| 5| 8| 2| 3| 3| 9|            |
                                           | 5| 7| 6| 7| 6| 5| 7| 5| 7| 6| 6| 0| 7| 4| 7| 2| 6| 6| 6| 6| 6| 3| 7| 7| 4|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|     A      |
    100 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 GENITAL SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
      Mast Cell Tumor Malignant,           |                                                                          |            |
          Metastatic, Uncertain Primary    |                                                                          |            |
          Site                             |                                                                          |          1 |
      Tubulostromal Adenoma                |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Uterus                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                           X                              |          2 |
      Mast Cell Tumor Malignant,           |                                                                          |            |
          Metastatic, Uncertain Primary    |                                                                          |            |
          Site                             |                                                                          |          1 |
      Polyp Stromal                        |                   X                                                      |          2 |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Hemangiosarcoma                      |                                                                          |          1 |
      Lymphoma Malignant                   |                                              X                           |          1 |
                                           |__________________________________________________________________________|____________|
   Lymph Node                              |    +                                +        +                           |   4        |
      Mast Cell Tumor Malignant,           |                                                                          |            |
          Metastatic, Uncertain Primary    |                                                                          |            |
          Site                             |                                                                          |          1 |
      Iliac, Lymphoma Malignant            |                                     X                                    |          1 |
      Iliac, Mast Cell Tumor Malignant,    |                                                                          |            |
           Metastatic, Uncertain Primary   |                                                                          |            |
          Site                             |                                                                          |          1 |
      Lumbar, Lymphoma Malignant           |                                              X                           |          1 |
      Pancreatic, Lymphoma Malignant       |                                              X                           |          1 |
      Renal, Lymphoma Malignant            |                                     X        X                           |          2 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Bronchial                   | +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +|  47        |
      Lymphoma Malignant                   |                                     X     X  X                       X   |          8 |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  36                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 3| 6| 7| 7| 7| 5|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 1| 3| 3| 3| 1| 3| 3| 3| 5| 8| 2| 3| 3| 9|            |
                                           | 5| 7| 6| 7| 6| 5| 7| 5| 7| 6| 6| 0| 7| 4| 7| 2| 6| 6| 6| 6| 6| 3| 7| 7| 4|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|     A      |
    100 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
      Mast Cell Tumor Malignant,           |                                                                          |            |
          Metastatic, Uncertain Primary    |                                                                          |            |
          Site                             |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mandibular                  | +  +  +  +  M  M  +  +  +  +  +  M  +  M  +  +  +  M  +  +  +  +  M  +  +|  37        |
      Carcinoma, Metastatic, Harderian     |                                                                          |            |
          Gland                            |                                                                      X   |          1 |
      Lymphoma Malignant                   |                                     X     X  X              X        X   |          8 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                  X  X     X  X                       X   |          8 |
      Mast Cell Tumor Malignant,           |                                                                          |            |
          Metastatic, Uncertain Primary    |                                                                          |            |
          Site                             |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mediastinal                 | +  +  +  M  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  43        |
      Lymphoma Malignant                   |                                     X     X  X                       X   |          8 |
      Mast Cell Tumor Malignant,           |                                                                          |            |
          Metastatic, Uncertain Primary    |                                                                          |            |
          Site                             |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Hemangiosarcoma                      |                                                                          |          1 |
      Lymphoma Malignant                   |                                     X     X  X                       X   |          8 |
                                           |__________________________________________________________________________|____________|
   Thymus                                  | +  +  +  +  +  +  +  M  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
      Lymphoma Malignant                   |                                     X     X  X                    X  X   |          6 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Mammary Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Carcinoma                            |                                                                X         |          2 |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  37                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 3| 6| 7| 7| 7| 5|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 1| 3| 3| 3| 1| 3| 3| 3| 5| 8| 2| 3| 3| 9|            |
                                           | 5| 7| 6| 7| 6| 5| 7| 5| 7| 6| 6| 0| 7| 4| 7| 2| 6| 6| 6| 6| 6| 3| 7| 7| 4|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|     A      |
    100 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 INTEGUMENTARY SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Neural Crest Tumor                   |                                                                          |          1 |
      Squamous Cell Papilloma              |    X                                                                     |          1 |
      Subcutaneous Tissue, Fibrosarcoma    |                X                                                         |          1 |
      Subcutaneous Tissue, Sarcoma         |                                        X                 X               |          2 |
      Subcutaneous Tissue, Schwannoma      |                                                                          |            |
          Malignant                        |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Carcinoma, Metastatic, Uncertain     |                                                                          |            |
          Primary Site                     |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Mast Cell Tumor Malignant,           |                                                                          |            |
          Metastatic, Uncertain Primary    |                                                                          |            |
          Site                             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Larynx                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Alveolar/Bronchiolar Carcinoma       |                                                                          |          1 |
      Carcinoma, Metastatic, Harderian     |                                                                          |            |
          Gland                            |                                                                      X   |          1 |
      Hepatocellular Carcinoma, Metastatic,|                                                                          |            |
           Liver                           |                               X                                          |          2 |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  38                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 3| 6| 7| 7| 7| 5|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 1| 3| 3| 3| 1| 3| 3| 3| 5| 8| 2| 3| 3| 9|            |
                                           | 5| 7| 6| 7| 6| 5| 7| 5| 7| 6| 6| 0| 7| 4| 7| 2| 6| 6| 6| 6| 6| 3| 7| 7| 4|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|     A      |
    100 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 RESPIRATORY SYSTEM - cont                 |                                                                          |            |
                                           |                                                                          |            |
      Lymphoma Malignant                   |                                     X     X  X                           |          6 |
      Mast Cell Tumor Malignant,           |                                                                          |            |
          Metastatic, Uncertain Primary    |                                                                          |            |
          Site                             |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Nose                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                              X                           |          1 |
      Mast Cell Tumor Malignant,           |                                                                          |            |
          Metastatic, Uncertain Primary    |                                                                          |            |
          Site                             |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Ear                                     |                                                                          |   1        |
                                           |__________________________________________________________________________|____________|
   Eye                                     |                                                                          |   2        |
      Carcinoma, Metastatic, Uncertain     |                                                                          |            |
          Primary Site                     |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Harderian Gland                         |                +                                            +     +  +   |   5        |
      Adenoma                              |                                                             X     X      |          2 |
      Carcinoma                            |                X                                                     X   |          3 |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                     X     X  X                           |          3 |
      Mast Cell Tumor Malignant,           |                                                                          |            |
          Metastatic, Uncertain Primary    |                                                                          |            |
          Site                             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  39                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 3| 6| 7| 7| 7| 5|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 1| 3| 3| 3| 1| 3| 3| 3| 5| 8| 2| 3| 3| 9|            |
                                           | 5| 7| 6| 7| 6| 5| 7| 5| 7| 6| 6| 0| 7| 4| 7| 2| 6| 6| 6| 6| 6| 3| 7| 7| 4|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|     A      |
    100 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 URINARY SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Lymphoma Malignant                   |                                     X     X  X                           |          3 |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                  X  X     X  X     X        X     X  X   |         13 |
 __________________________________________________________________________________________________________________________________ 
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  40                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 6| 7| 7| 7| 6| 7| 7| 7| 6| 7| 3| 7| 7| 7| 7| 7| 7| 7| 4| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 3| 8| 3| 1| 2| 3| 1| 3| 1| 7| 3| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
                                           | 6| 6| 7| 7| 6| 6| 0| 1| 6| 4| 5| 4| 4| 7| 9| 5| 6| 6| 5| 6| 7| 6| 2| 7| 5|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|             
    400 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |__________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Gallbladder                             | +  +  +  +  M  +  A  M  A  +  I  +  +  +  +  +  +  +  M  +  M  +  A  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +  +  A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +  +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
      Polyp Adenomatous                    |                                                                          |             
                                           |__________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +  +  A  A  +  +  +  +  +  +  A  +  +  +  +  +  +  +  A  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
                                           |__________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hemangiosarcoma                      |                                                                X         |             
      Hepatoblastoma                       |                                                                          |             
      Hepatocellular Carcinoma             |       X              X  X                                            X   |             
      Hepatocellular Adenoma               |          X     X           X     X                          X           X|             
      Hepatocellular Adenoma, Multiple     |                      X                                                   |             
      Lymphoma Malignant                   |             X  X     X  X                                X  X            |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                         X                                                |             
                                           |__________________________________________________________________________|             
   Mesentery                               | +        +        +  +           +     +           +        +            |             
      Lymphoma Malignant                   |                                                                          |             
                                           |__________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
      Lymphoma Malignant                   |             X           X                                      X         |             
                                           |__________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                         X                                      X         |             
                                           |__________________________________________________________________________|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  41                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 6| 7| 7| 7| 6| 7| 7| 7| 6| 7| 3| 7| 7| 7| 7| 7| 7| 7| 4| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 3| 8| 3| 1| 2| 3| 1| 3| 1| 7| 3| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
                                           | 6| 6| 7| 7| 6| 6| 0| 1| 6| 4| 5| 4| 4| 7| 9| 5| 6| 6| 5| 6| 7| 6| 2| 7| 5|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|             
    400 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
   Stomach, Forestomach                    | +  +  +  +  +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
      Lymphoma Malignant                   |                                                             X            |             
      Squamous Cell Carcinoma              |                                                                          |             
                                           |__________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
      Lymphoma Malignant                   |                                                                          |             
                                           |__________________________________________________________________________|             
   Tooth                                   |          +                                                               |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                                                          |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                         X                                                |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |__________________________________________________________________________|             
   Adrenal Cortex                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
      Lymphoma Malignant                   |                                                                          |             
                                           |__________________________________________________________________________|             
   Adrenal Medulla                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
      Pheochromocytoma Benign              |                                                                          |             
                                           |__________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
                                           |__________________________________________________________________________|             
   Parathyroid Gland                       | M  +  +  M  +  +  +  M  M  +  I  +  M  +  M  +  +  M  +  +  +  +  M  +  +|             
                                           |__________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                                                          |             
      Pars Distalis, Adenoma               |                            X                 X  X     X                 X|             
      Pars Intermedia, Adenoma             |                                        X                                 |             
                                           |__________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  M  +|             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
    None                                   |                                                                          |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                             Page  42                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 6| 7| 7| 7| 6| 7| 7| 7| 6| 7| 3| 7| 7| 7| 7| 7| 7| 7| 4| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 3| 8| 3| 1| 2| 3| 1| 3| 1| 7| 3| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
                                           | 6| 6| 7| 7| 6| 6| 0| 1| 6| 4| 5| 4| 4| 7| 9| 5| 6| 6| 5| 6| 7| 6| 2| 7| 5|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|             
    400 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Clitoral Gland                          | +  +  +  M  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +|             
                                           |__________________________________________________________________________|             
   Ovary                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
      Cystadenoma                          |                   X                                                      |             
      Granulosa Cell Tumor Malignant       |                                                                          |             
      Granulosa Cell Tumor Benign          |                                                                          |             
      Lymphoma Malignant                   |                                                          X     X         |             
                                           |__________________________________________________________________________|             
   Uterus                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
      Hemangiosarcoma                      |                                                                          |             
      Lymphoma Malignant                   |                                                          X               |             
      Polyp Stromal                        |    X                                                  X                  |             
      Sarcoma Stromal                      |                                        X                                 |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |__________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
      Hemangiosarcoma                      |                                                                          |             
                                           |__________________________________________________________________________|             
   Lymph Node                              |                         +                                                |             
      Renal, Lymphoma Malignant            |                         X                                                |             
                                           |__________________________________________________________________________|             
   Lymph Node, Bronchial                   | +  +  +  +  +  +  +  +  +  +  +  +  M  +  M  +  +  +  +  +  +  +  A  +  M|             
      Lymphoma Malignant                   |             X                                            X  X  X         |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                         X                                                |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mandibular                  | +  +  M  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                X     X  X                                X  X  X         |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
      Lymphoma Malignant                   |             X  X     X  X                                X  X  X         |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                         X                                                |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mediastinal                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  A  +  +|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  43                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 6| 7| 7| 7| 6| 7| 7| 7| 6| 7| 3| 7| 7| 7| 7| 7| 7| 7| 4| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 3| 8| 3| 1| 2| 3| 1| 3| 1| 7| 3| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
                                           | 6| 6| 7| 7| 6| 6| 0| 1| 6| 4| 5| 4| 4| 7| 9| 5| 6| 6| 5| 6| 7| 6| 2| 7| 5|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|             
    400 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Lymphoma Malignant                   |             X           X                                X  X  X         |             
      Osteosarcoma, Metastatic, Uncertain  |                                                                          |             
          Primary Site                     |             X                                                            |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                         X                                                |             
                                           |__________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
      Hemangiosarcoma                      |                                                    X                     |             
      Lymphoma Malignant                   |    X        X  X     X  X                                X  X  X         |             
                                           |__________________________________________________________________________|             
   Thymus                                  | +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
      Lymphoma Malignant                   |                                                                          |             
      Thymoma Benign                       |                            X                                             |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |__________________________________________________________________________|             
   Mammary Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Mast Cell Tumor Benign               |                                                                          |             
      Subcutaneous Tissue, Fibrous         |                                                                          |             
          Histiocytoma                     |                                                                          |             
      Subcutaneous Tissue, Hemangiosarcoma |                                                                          |             
      Subcutaneous Tissue, Sarcoma         |                                  X                                       |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |__________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Spinal Cord                             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  44                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 6| 7| 7| 7| 6| 7| 7| 7| 6| 7| 3| 7| 7| 7| 7| 7| 7| 7| 4| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 3| 8| 3| 1| 2| 3| 1| 3| 1| 7| 3| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
                                           | 6| 6| 7| 7| 6| 6| 0| 1| 6| 4| 5| 4| 4| 7| 9| 5| 6| 6| 5| 6| 7| 6| 2| 7| 5|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|             
    400 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 RESPIRATORY SYSTEM - cont                 |                                                                          |             
                                           |                                                                          |             
                                           |__________________________________________________________________________|             
   Larynx                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
                                           |__________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Alveolar/Bronchiolar Adenoma         |    X                       X                    X                        |             
      Alveolar/Bronchiolar Carcinoma       |          X                                                               |             
      Hemangiosarcoma, Metastatic, Liver   |                                                                X         |             
      Lymphoma Malignant                   |             X           X                                X  X            |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                         X                                                |             
                                           |__________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                                          X               |             
                                           |__________________________________________________________________________|             
   Pleura                                  |                         +                                                |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                         X                                                |             
                                           |__________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Harderian Gland                         |       +                 +                                                |             
      Adenoma                              |       X                 X                                                |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |             X  X     X  X                                                |             
                                           |__________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|             
      Lymphoma Malignant                   |                                                             X  X         |             
 __________________________________________|__________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |    X        X  X     X  X                                X  X  X         |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                             Page  45                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 6| 7| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 3| 3| 3| 2| 3| 4| 2| 3| 1| 3| 3| 3| 3| 3| 3|            |
                                           | 7| 7| 6| 5| 6| 5| 7| 5| 5| 4| 6| 5| 7| 4| 7| 4| 7| 6| 4| 6| 5| 5| 6| 5| 7|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|     A      |
    400 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Gallbladder                             | I  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  I  +  M  +|  38        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  46        |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  47        |
      Polyp Adenomatous                    | X                                                                        |          1 |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +|  45        |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  47        |
                                           |__________________________________________________________________________|____________|
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Hemangiosarcoma                      |                                                                          |          1 |
      Hepatoblastoma                       |                                                 X                        |          1 |
      Hepatocellular Carcinoma             |    X                                                                     |          5 |
      Hepatocellular Adenoma               |    X  X     X     X           X                                X     X  X|         14 |
      Hepatocellular Adenoma, Multiple     |          X                                                        X      |          3 |
      Lymphoma Malignant                   |          X                 X           X                                 |          9 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Mesentery                               | +  +     +        +  +  +              +                 +  +     +      |  18        |
      Lymphoma Malignant                   |                                        X                                 |          1 |
                                           |__________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Lymphoma Malignant                   |          X                             X                                 |          5 |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  46                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 6| 7| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 3| 3| 3| 2| 3| 4| 2| 3| 1| 3| 3| 3| 3| 3| 3|            |
                                           | 7| 7| 6| 5| 6| 5| 7| 5| 5| 4| 6| 5| 7| 4| 7| 4| 7| 6| 4| 6| 5| 5| 6| 5| 7|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|     A      |
    400 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                                                          |          2 |
                                           |__________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  47        |
      Lymphoma Malignant                   |                                        X                                 |          2 |
      Squamous Cell Carcinoma              |                                                                   X      |          1 |
                                           |__________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  47        |
      Lymphoma Malignant                   |                                        X                                 |          1 |
                                           |__________________________________________________________________________|____________|
   Tooth                                   |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                            X                                             |          1 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Adrenal Cortex                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Lymphoma Malignant                   |                                        X                                 |          1 |
                                           |__________________________________________________________________________|____________|
   Adrenal Medulla                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Pheochromocytoma Benign              |                            X                                             |          1 |
                                           |__________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Parathyroid Gland                       | +  M  +  +  +  +  +  +  +  M  M  +  I  +  +  +  +  +  +  +  +  +  +  +  +|  37        |
                                           |__________________________________________________________________________|____________|
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  47                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 6| 7| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 3| 3| 3| 2| 3| 4| 2| 3| 1| 3| 3| 3| 3| 3| 3|            |
                                           | 7| 7| 6| 5| 6| 5| 7| 5| 5| 4| 6| 5| 7| 4| 7| 4| 7| 6| 4| 6| 5| 5| 6| 5| 7|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|     A      |
    400 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                        X                                 |          1 |
      Pars Distalis, Adenoma               | X     X  X                    X     X           X     X  X     X  X  X  X|         17 |
      Pars Intermedia, Adenoma             |                         X                                                |          2 |
                                           |__________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M|  47        |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Clitoral Gland                          | +  +  +  M  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  I  +  +|  44        |
                                           |__________________________________________________________________________|____________|
   Ovary                                   | +  +  +  +  +  +  I  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
      Cystadenoma                          |                                                             X            |          2 |
      Granulosa Cell Tumor Malignant       |       X                                                                  |          1 |
      Granulosa Cell Tumor Benign          |                            X                                             |          1 |
      Lymphoma Malignant                   |    X     X                                                               |          4 |
                                           |__________________________________________________________________________|____________|
   Uterus                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Hemangiosarcoma                      |             X                                                            |          1 |
      Lymphoma Malignant                   |                                        X                                 |          2 |
      Polyp Stromal                        |                                  X                                       |          3 |
      Sarcoma Stromal                      |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
      Hemangiosarcoma                      |                   X                                                      |          1 |
                                           |__________________________________________________________________________|____________|
   Lymph Node                              |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  48                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 6| 7| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 3| 3| 3| 2| 3| 4| 2| 3| 1| 3| 3| 3| 3| 3| 3|            |
                                           | 7| 7| 6| 5| 6| 5| 7| 5| 5| 4| 6| 5| 7| 4| 7| 4| 7| 6| 4| 6| 5| 5| 6| 5| 7|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|     A      |
    400 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
      Renal, Lymphoma Malignant            |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Bronchial                   | +  +  +  +  +  +  +  +  +  +  +  M  +  +  M  +  +  +  +  +  +  +  +  +  +|  44        |
      Lymphoma Malignant                   |    X                                   X           X                     |          7 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mandibular                  | +  M  M  +  +  M  +  +  +  +  +  +  +  +  M  +  M  +  +  +  M  +  +  +  M|  41        |
      Lymphoma Malignant                   |          X                             X           X                     |          9 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  47        |
      Lymphoma Malignant                   |    X     X                             X           X                     |         11 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mediastinal                 | +  +  +  +  +  M  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +|  46        |
      Lymphoma Malignant                   |    X     X                             X           X                     |          9 |
      Osteosarcoma, Metastatic, Uncertain  |                                                                          |            |
          Primary Site                     |                                                                          |          1 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
      Hemangiosarcoma                      |             X                                                            |          2 |
      Lymphoma Malignant                   |    X     X                 X        X  X           X                     |         14 |
                                           |__________________________________________________________________________|____________|
   Thymus                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +|  47        |
      Lymphoma Malignant                   |    X                       X           X                                 |          3 |
      Thymoma Benign                       |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |__________________________________________________________________________|____________|
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  49                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 6| 7| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 3| 3| 3| 2| 3| 4| 2| 3| 1| 3| 3| 3| 3| 3| 3|            |
                                           | 7| 7| 6| 5| 6| 5| 7| 5| 5| 4| 6| 5| 7| 4| 7| 4| 7| 6| 4| 6| 5| 5| 6| 5| 7|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|     A      |
    400 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 INTEGUMENTARY SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
   Mammary Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Mast Cell Tumor Benign               |                                                                   X      |          1 |
      Subcutaneous Tissue, Fibrous         |                                                                          |            |
          Histiocytoma                     |                         X                                                |          1 |
      Subcutaneous Tissue, Hemangiosarcoma |                   X                                                      |          1 |
      Subcutaneous Tissue, Sarcoma         |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Spinal Cord                             |                                              +                           |   1        |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Larynx                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Alveolar/Bronchiolar Adenoma         |                                                 X                        |          4 |
      Alveolar/Bronchiolar Carcinoma       |                                                                          |          1 |
      Hemangiosarcoma, Metastatic, Liver   |                                                                          |          1 |
      Lymphoma Malignant                   |                                        X                                 |          5 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Nose                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  50                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 6| 7| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 3| 3| 3| 2| 3| 4| 2| 3| 1| 3| 3| 3| 3| 3| 3|            |
                                           | 7| 7| 6| 5| 6| 5| 7| 5| 5| 4| 6| 5| 7| 4| 7| 4| 7| 6| 4| 6| 5| 5| 6| 5| 7|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|     A      |
    400 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 RESPIRATORY SYSTEM - cont                 |                                                                          |            |
                                           |                                                                          |            |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Pleura                                  |                                                                          |   1        |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Harderian Gland                         |                   +                                                      |   3        |
      Adenoma                              |                                                                          |          2 |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                        X                                 |          5 |
                                           |__________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  47        |
      Lymphoma Malignant                   |                                        X                                 |          3 |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |    X     X                 X        X  X           X                     |         14 |
 __________________________________________________________________________________________________________________________________ 
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  51                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 6| 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 4| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 3| 4| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 7| 3| 2| 3| 3|             
                                           | 3| 5| 3| 3| 9| 4| 4| 5| 3| 4| 3| 4| 3| 3| 3| 4| 4| 5| 5| 4| 4| 3| 1| 5| 5|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |__________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Gallbladder                             | M  +  +  I  +  M  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                      X                                                   |             
                                           |__________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Polyp Adenomatous                    |                                        X                                 |             
                                           |__________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hemangiosarcoma                      |                         X                                                |             
      Hepatocellular Carcinoma             | X              X                 X  X              X     X               |             
      Hepatocellular Adenoma               |          X  X     X  X              X        X           X           X  X|             
      Hepatocellular Adenoma, Multiple     |                         X     X                    X                     |             
      Lymphoma Malignant                   |                      X                                                   |             
                                           |__________________________________________________________________________|             
   Mesentery                               | +           +           +  +  +           +  +                           |             
                                           |__________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                      X                                                   |             
                                           |__________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                      X                                                   |             
                                           |__________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                      X                                                   |             
                                           |__________________________________________________________________________|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  52                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 6| 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 4| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 3| 4| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 7| 3| 2| 3| 3|             
                                           | 3| 5| 3| 3| 9| 4| 4| 5| 3| 4| 3| 4| 3| 3| 3| 4| 4| 5| 5| 4| 4| 3| 1| 5| 5|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                      X                                                   |             
                                           |__________________________________________________________________________|             
   Tongue                                  |                                                                          |             
                                           |__________________________________________________________________________|             
   Tooth                                   | +  +                 +  +  +  +  +  +  +     +  +              +         |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Blood Vessel                            |                                                                   +      |             
                                           |__________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hemangiosarcoma                      |                         X                                                |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |__________________________________________________________________________|             
   Adrenal Cortex                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Subcapsular, Adenoma                 |                               X                                          |             
                                           |__________________________________________________________________________|             
   Adrenal Medulla                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Adenoma                              |                   X                                                      |             
                                           |__________________________________________________________________________|             
   Parathyroid Gland                       | +  +  M  +  +  +  +  +  +  M  M  M  +  +  +  +  I  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Pars Distalis, Adenoma               |                            X                                             |             
                                           |__________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  53                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 6| 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 4| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 3| 4| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 7| 3| 2| 3| 3|             
                                           | 3| 5| 3| 3| 9| 4| 4| 5| 3| 4| 3| 4| 3| 3| 3| 4| 4| 5| 5| 4| 4| 3| 1| 5| 5|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
   Coagulating Gland                       |          +                                                               |             
      Adenoma                              |          X                                                               |             
                                           |__________________________________________________________________________|             
   Epididymis                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                      X                                                   |             
                                           |__________________________________________________________________________|             
   Preputial Gland                         | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Prostate                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  I  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Seminal Vesicle                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                      X                                                   |             
                                           |__________________________________________________________________________|             
   Testes                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |__________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hemangiosarcoma                      |                         X                                                |             
      Lymphoma Malignant                   |                                                                          |             
                                           |__________________________________________________________________________|             
   Lymph Node                              |                      +                                                   |             
      Renal, Lymphoma Malignant            |                      X                                                   |             
                                           |__________________________________________________________________________|             
   Lymph Node, Bronchial                   | M  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                      X                                                   |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mandibular                  | +  +  +  M  M  +  M  M  M  M  M  +  M  M  +  M  +  +  +  +  +  +  +  M  +|             
      Carcinoma, Metastatic, Harderian     |                                                                          |             
          Gland                            |                                                             X            |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                      X                                                   |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mediastinal                 | +  +  +  M  +  +  +  +  +  M  +  +  +  +  M  +  +  M  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                      X                                                   |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  54                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 6| 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 4| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 3| 4| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 7| 3| 2| 3| 3|             
                                           | 3| 5| 3| 3| 9| 4| 4| 5| 3| 4| 3| 4| 3| 3| 3| 4| 4| 5| 5| 4| 4| 3| 1| 5| 5|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
                                           |__________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                      X                                   X               |             
                                           |__________________________________________________________________________|             
   Thymus                                  | M  M  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  M  +  +  +  +  +|             
      Lymphoma Malignant                   |                      X                                                   |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |__________________________________________________________________________|             
   Mammary Gland                           | M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M|             
                                           |__________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |__________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |__________________________________________________________________________|             
   Larynx                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Alveolar/Bronchiolar Adenoma         |             X  X                             X           X     X         |             
      Alveolar/Bronchiolar Adenoma,        |                                                                          |             
          Multiple                         |                                        X                                 |             
      Alveolar/Bronchiolar Carcinoma       |             X           X  X              X                              |             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Multiple                         |    X              X                                                      |             
      Carcinoma, Metastatic, Harderian     |                                                                          |             
          Gland                            |                                                       X     X            |             
      Hepatocellular Carcinoma, Metastatic,|                                                                          |             
           Liver                           |                X                    X                                    |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  55                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 6| 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 4| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 3| 4| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 7| 3| 2| 3| 3|             
                                           | 3| 5| 3| 3| 9| 4| 4| 5| 3| 4| 3| 4| 3| 3| 3| 4| 4| 5| 5| 4| 4| 3| 1| 5| 5|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 RESPIRATORY SYSTEM - cont                 |                                                                          |             
                                           |                                                                          |             
      Lymphoma Malignant                   |                      X                                                   |             
      Mediastinum, Lymphoma Malignant      |                      X                                                   |             
                                           |__________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Ear                                     |                                                                   +      |             
                                           |__________________________________________________________________________|             
   Eye                                     |       +                                   +                 +            |             
                                           |__________________________________________________________________________|             
   Harderian Gland                         |       +                                   +           +     +           +|             
      Adenoma                              |       X                                   X                             X|             
      Carcinoma                            |                                                       X     X            |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                      X                                                   |             
 __________________________________________|__________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                      X                                   X               |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  56                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 3| 4| 7| 7| 6| 7| 7| 7| 7| 5| 7| 7| 7| 7| 7| 7| 6| 6| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 8| 7| 3| 3| 4| 3| 3| 3| 3| 8| 3| 3| 3| 3| 3| 3| 6| 0| 3| 3|            |
                                           | 4| 5| 4| 3| 5| 4| 6| 4| 3| 2| 4| 3| 4| 4| 8| 4| 3| 3| 4| 3| 4| 5| 6| 3| 3|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     A      |
    CONTROL                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Gallbladder                             | +  +  +  +  +  A  +  +  +  A  +  +  +  +  +  M  +  +  +  +  +  +  A  +  +|  42        |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|  48        |
      Polyp Adenomatous                    |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|  47        |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  +  +  A  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|  46        |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  +  +  A  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +|  46        |
                                           |__________________________________________________________________________|____________|
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Hemangiosarcoma                      |                                                                          |          1 |
      Hepatocellular Carcinoma             |                X           X              X                       X      |         10 |
      Hepatocellular Adenoma               |    X              X  X  X     X           X           X                  |         16 |
      Hepatocellular Adenoma, Multiple     |             X                    X           X                           |          6 |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Mesentery                               |          +        +     +                       +     +     +  +         |  14        |
                                           |__________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  57                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 3| 4| 7| 7| 6| 7| 7| 7| 7| 5| 7| 7| 7| 7| 7| 7| 6| 6| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 8| 7| 3| 3| 4| 3| 3| 3| 3| 8| 3| 3| 3| 3| 3| 3| 6| 0| 3| 3|            |
                                           | 4| 5| 4| 3| 5| 4| 6| 4| 3| 2| 4| 3| 4| 4| 8| 4| 3| 3| 4| 3| 4| 5| 6| 3| 3|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     A      |
    CONTROL                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Tongue                                  | +                                                                        |   1        |
                                           |__________________________________________________________________________|____________|
   Tooth                                   | +  +  +  +           +  +              +     +  +           +        +   |  23        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Blood Vessel                            |                                                                          |   1        |
                                           |__________________________________________________________________________|____________|
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Hemangiosarcoma                      |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Adrenal Cortex                          | +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Subcapsular, Adenoma                 |                                                    X                     |          2 |
                                           |__________________________________________________________________________|____________|
   Adrenal Medulla                         | +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Adenoma                              |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Parathyroid Gland                       | M  +  +  +  M  +  +  +  M  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  41        |
                                           |__________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  M  +  +  +  I  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
      Pars Distalis, Adenoma               |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  58                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 3| 4| 7| 7| 6| 7| 7| 7| 7| 5| 7| 7| 7| 7| 7| 7| 6| 6| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 8| 7| 3| 3| 4| 3| 3| 3| 3| 8| 3| 3| 3| 3| 3| 3| 6| 0| 3| 3|            |
                                           | 4| 5| 4| 3| 5| 4| 6| 4| 3| 2| 4| 3| 4| 4| 8| 4| 3| 3| 4| 3| 4| 5| 6| 3| 3|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     A      |
    CONTROL                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Coagulating Gland                       |                                                                          |   1        |
      Adenoma                              |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Epididymis                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Preputial Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Prostate                                | +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
                                           |__________________________________________________________________________|____________|
   Seminal Vesicle                         | +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Testes                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Hemangiosarcoma                      |                                                                          |          1 |
      Lymphoma Malignant                   |                                                                      X   |          1 |
                                           |__________________________________________________________________________|____________|
   Lymph Node                              |                                                                          |   1        |
      Renal, Lymphoma Malignant            |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  59                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 3| 4| 7| 7| 6| 7| 7| 7| 7| 5| 7| 7| 7| 7| 7| 7| 6| 6| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 8| 7| 3| 3| 4| 3| 3| 3| 3| 8| 3| 3| 3| 3| 3| 3| 6| 0| 3| 3|            |
                                           | 4| 5| 4| 3| 5| 4| 6| 4| 3| 2| 4| 3| 4| 4| 8| 4| 3| 3| 4| 3| 4| 5| 6| 3| 3|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     A      |
    CONTROL                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
   Lymph Node, Bronchial                   | +  +  +  +  M  M  +  +  +  +  M  +  M  +  +  +  M  +  +  M  +  +  +  +  +|  42        |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mandibular                  | M  +  +  +  M  +  +  +  +  +  +  +  M  M  +  M  +  +  +  +  M  M  +  M  +|  31        |
      Carcinoma, Metastatic, Harderian     |                                                                          |            |
          Gland                            |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Lymphoma Malignant                   |                                                                      X   |          2 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mediastinal                 | M  +  +  +  +  +  +  +  M  +  +  M  +  +  +  +  +  +  M  +  M  +  +  +  +|  41        |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Lymphoma Malignant                   |                                                                      X   |          3 |
                                           |__________________________________________________________________________|____________|
   Thymus                                  | M  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  44        |
      Lymphoma Malignant                   |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Mammary Gland                           | M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M|            |
                                           |__________________________________________________________________________|____________|
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  60                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 3| 4| 7| 7| 6| 7| 7| 7| 7| 5| 7| 7| 7| 7| 7| 7| 6| 6| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 8| 7| 3| 3| 4| 3| 3| 3| 3| 8| 3| 3| 3| 3| 3| 3| 6| 0| 3| 3|            |
                                           | 4| 5| 4| 3| 5| 4| 6| 4| 3| 2| 4| 3| 4| 4| 8| 4| 3| 3| 4| 3| 4| 5| 6| 3| 3|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     A      |
    CONTROL                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Larynx                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Alveolar/Bronchiolar Adenoma         |                                                             X            |          6 |
      Alveolar/Bronchiolar Adenoma,        |                                                                          |            |
          Multiple                         | X                                                                        |          2 |
      Alveolar/Bronchiolar Carcinoma       |             X                       X                                    |          6 |
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |            |
          Multiple                         |                                                                          |          2 |
      Carcinoma, Metastatic, Harderian     |                                                                          |            |
          Gland                            |                                                                          |          2 |
      Hepatocellular Carcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                           X                              |          3 |
      Lymphoma Malignant                   |                                                                          |          1 |
      Mediastinum, Lymphoma Malignant      |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Nose                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Ear                                     |                                                                          |   1        |
                                           |__________________________________________________________________________|____________|
   Eye                                     |                                                                          |   3        |
                                           |__________________________________________________________________________|____________|
   Harderian Gland                         |          +                                +     +  +                     |   9        |
      Adenoma                              |                                           X     X  X                     |          6 |
      Carcinoma                            |          X                                                               |          3 |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  61                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 3| 4| 7| 7| 6| 7| 7| 7| 7| 5| 7| 7| 7| 7| 7| 7| 6| 6| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 8| 7| 3| 3| 4| 3| 3| 3| 3| 8| 3| 3| 3| 3| 3| 3| 6| 0| 3| 3|            |
                                           | 4| 5| 4| 3| 5| 4| 6| 4| 3| 2| 4| 3| 4| 4| 8| 4| 3| 3| 4| 3| 4| 5| 6| 3| 3|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     A      |
    CONTROL                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 URINARY SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
   Kidney                                  | +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Lymphoma Malignant                   |                                                                          |          1 |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                                                      X   |          3 |
 __________________________________________________________________________________________________________________________________ 
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  62                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 4| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 6| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 9| 3| 3| 3| 9| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 5| 3| 3| 1| 3|             
                                           | 3| 5| 5| 4| 4| 5| 7| 3| 4| 5| 3| 4| 3| 3| 4| 3| 4| 3| 2| 5| 8| 4| 4| 8| 4|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    25 PPM                                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |__________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Gallbladder                             | +  +  +  +  +  I  +  M  +  +  +  +  +  +  +  +  I  I  +  +  +  +  +  A  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +|             
      Carcinoma                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +|             
                                           |__________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Cholangioma                          |                                                                          |             
      Hemangiosarcoma                      |             X                                                            |             
      Hepatoblastoma                       |                                  X                                       |             
      Hepatocellular Carcinoma             |                   X                                         X            |             
      Hepatocellular Adenoma               |       X  X  X                 X        X        X  X  X  X               |             
      Hepatocellular Adenoma, Multiple     |                                           X                              |             
      Lymphoma Malignant                   |                         X                                                |             
                                           |__________________________________________________________________________|             
   Mesentery                               |       +                       +  +              +  +  +  +               |             
                                           |__________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  63                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 4| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 6| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 9| 3| 3| 3| 9| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 5| 3| 3| 1| 3|             
                                           | 3| 5| 5| 4| 4| 5| 7| 3| 4| 5| 3| 4| 3| 3| 4| 3| 4| 3| 2| 5| 8| 4| 4| 8| 4|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    25 PPM                                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
   Tooth                                   | +  +        +  +     +  +  +  +     +        +           +     +        +|             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Blood Vessel                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hemangiosarcoma                      |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |__________________________________________________________________________|             
   Adrenal Cortex                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Subcapsular, Adenoma                 |                                                                          |             
                                           |__________________________________________________________________________|             
   Adrenal Medulla                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Parathyroid Gland                       | +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  M  +  +  M  +  +  M  +  +|             
                                           |__________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Pars Distalis, Adenoma               |                                                                          |             
                                           |__________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  I  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |__________________________________________________________________________|             
   Tissue NOS                              |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Epididymis                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Preputial Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Prostate                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  64                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 4| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 6| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 9| 3| 3| 3| 9| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 5| 3| 3| 1| 3|             
                                           | 3| 5| 5| 4| 4| 5| 7| 3| 4| 5| 3| 4| 3| 3| 4| 3| 4| 3| 2| 5| 8| 4| 4| 8| 4|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    25 PPM                                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                           |__________________________________________________________________________|             
   Seminal Vesicle                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Testes                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |__________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Lymph Node, Bronchial                   | +  +  M  +  M  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  M  +  +|             
      Lymphoma Malignant                   |                         X                                                |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mandibular                  | +  M  +  +  +  +  +  M  +  +  +  +  +  +  M  +  +  +  +  M  +  +  +  +  M|             
      Lymphoma Malignant                   |                                                                          |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  +  +  I  +  +  +  +  +  +  +  +  +  +  +  +  M  +|             
      Lymphoma Malignant                   |          X                                                               |             
      Plasma Cell Tumor Malignant          |                                                                          |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mediastinal                 | +  +  +  +  M  +  +  M  M  +  +  +  +  +  +  +  +  M  +  I  +  +  M  +  +|             
      Lymphoma Malignant                   |                                                                          |             
                                           |__________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hemangiosarcoma                      |    X                                   X                             X   |             
      Lymphoma Malignant                   |          X              X                                                |             
                                           |__________________________________________________________________________|             
   Thymus                                  | +  +  +  +  +  +  I  +  +  +  +  +  +  M  +  +  +  +  +  +  M  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |__________________________________________________________________________|             
   Mammary Gland                           | M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M|             
                                           |__________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Squamous Cell Papilloma              |                                                    X                     |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  65                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 4| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 6| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 9| 3| 3| 3| 9| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 5| 3| 3| 1| 3|             
                                           | 3| 5| 5| 4| 4| 5| 7| 3| 4| 5| 3| 4| 3| 3| 4| 3| 4| 3| 2| 5| 8| 4| 4| 8| 4|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    25 PPM                                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM - cont             |                                                                          |             
                                           |                                                                          |             
                                           |__________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Spinal Cord                             |             M                                                            |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |__________________________________________________________________________|             
   Larynx                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Alveolar/Bronchiolar Adenoma         |                      X              X                                    |             
      Alveolar/Bronchiolar Carcinoma       |          X        X                    X     X                           |             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Multiple                         |                                                                   X      |             
      Hepatocellular Carcinoma, Metastatic,|                                                                          |             
           Liver                           |                   X                                                      |             
      Lymphoma Malignant                   |                         X                                                |             
                                           |__________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Ear                                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Eye                                     |             +                                                           +|             
                                           |__________________________________________________________________________|             
   Harderian Gland                         |             +                                                        +  +|             
      Adenoma                              |                                                                      X   |             
      Carcinoma                            |             X                                                            |             
      Bilateral, Adenoma                   |                                                                         X|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  66                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 4| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 6| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 9| 3| 3| 3| 9| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 5| 3| 3| 1| 3|             
                                           | 3| 5| 5| 4| 4| 5| 7| 3| 4| 5| 3| 4| 3| 3| 4| 3| 4| 3| 2| 5| 8| 4| 4| 8| 4|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    25 PPM                                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 __________________________________________|__________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |          X              X                                                |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  67                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2| 7| 5| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 6| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 0| 3| 7| 3|            |
                                           | 4| 4| 3| 3| 5| 5| 4| 3| 9| 4| 1| 4| 3| 5| 4| 4| 4| 4| 5| 3| 5| 3| 5| 5| 5|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|     A      |
    25 PPM                                 | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Gallbladder                             | +  +  +  +  +  +  +  I  A  +  +  +  I  +  I  +  +  +  +  M  +  +  +  +  +|  40        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
      Carcinoma                            |                                                 X                        |          1 |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
                                           |__________________________________________________________________________|____________|
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Cholangioma                          |                                                                   X      |          1 |
      Hemangiosarcoma                      |       X                                         X                        |          3 |
      Hepatoblastoma                       |                                                                          |          1 |
      Hepatocellular Carcinoma             |       X                 X     X  X                          X            |          7 |
      Hepatocellular Adenoma               |          X              X                 X  X           X  X     X      |         16 |
      Hepatocellular Adenoma, Multiple     |                                  X  X  X           X                    X|          6 |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Mesentery                               |       +  +     +     +                                                   |  11        |
                                           |__________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  68                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2| 7| 5| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 6| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 0| 3| 7| 3|            |
                                           | 4| 4| 3| 3| 5| 5| 4| 3| 9| 4| 1| 4| 3| 5| 4| 4| 4| 4| 5| 3| 5| 3| 5| 5| 5|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|     A      |
    25 PPM                                 | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Tooth                                   | +  +     +  +     +        +     +  +           +     +           +  +  +|  26        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Blood Vessel                            |    +                                            +                    +   |   3        |
                                           |__________________________________________________________________________|____________|
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Hemangiosarcoma                      |                                                 X                        |          1 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Adrenal Cortex                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Subcapsular, Adenoma                 | X                                                                        |          1 |
                                           |__________________________________________________________________________|____________|
   Adrenal Medulla                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Parathyroid Gland                       | +  +  +  +  +  M  +  +  +  M  +  +  +  +  +  I  +  M  +  +  +  +  +  +  M|  41        |
                                           |__________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Pars Distalis, Adenoma               |                                                             X            |          1 |
                                           |__________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Tissue NOS                              |                                              +                           |   1        |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  69                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2| 7| 5| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 6| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 0| 3| 7| 3|            |
                                           | 4| 4| 3| 3| 5| 5| 4| 3| 9| 4| 1| 4| 3| 5| 4| 4| 4| 4| 5| 3| 5| 3| 5| 5| 5|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|     A      |
    25 PPM                                 | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 GENITAL SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Epididymis                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Preputial Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  I  +|  49        |
                                           |__________________________________________________________________________|____________|
   Prostate                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Seminal Vesicle                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Testes                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Bronchial                   | +  +  +  +  M  M  M  +  M  +  M  +  +  M  +  M  +  +  +  +  +  M  +  M  M|  36        |
      Lymphoma Malignant                   |                                                 X                        |          2 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mandibular                  | +  +  M  M  +  +  +  +  M  +  +  M  +  M  +  M  +  +  +  +  M  +  +  M  M|  36        |
      Lymphoma Malignant                   |                                                 X                        |          1 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
      Lymphoma Malignant                   |                                                 X                        |          2 |
      Plasma Cell Tumor Malignant          |    X                                                                     |          1 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mediastinal                 | +  +  +  M  +  +  M  M  +  +  M  +  M  +  +  +  +  +  +  +  M  +  +  M  M|  36        |
      Lymphoma Malignant                   |                                                 X                        |          1 |
                                           |__________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Hemangiosarcoma                      |                                                                          |          3 |
      Lymphoma Malignant                   |                                                 X                        |          3 |
                                           |__________________________________________________________________________|____________|
   Thymus                                  | +  M  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +|  44        |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  70                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2| 7| 5| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 6| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 0| 3| 7| 3|            |
                                           | 4| 4| 3| 3| 5| 5| 4| 3| 9| 4| 1| 4| 3| 5| 4| 4| 4| 4| 5| 3| 5| 3| 5| 5| 5|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|     A      |
    25 PPM                                 | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Mammary Gland                           | M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M|            |
                                           |__________________________________________________________________________|____________|
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Squamous Cell Papilloma              |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Spinal Cord                             |                                                 M                        |            |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Larynx                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Alveolar/Bronchiolar Adenoma         |          X                                   X           X               |          5 |
      Alveolar/Bronchiolar Carcinoma       |       X           X                 X                                    |          7 |
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |            |
          Multiple                         |                                                                          |          1 |
      Hepatocellular Carcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Nose                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 _____________________________________________________________________________________________________________________|            |
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  71                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2| 7| 5| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 6| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 0| 3| 7| 3|            |
                                           | 4| 4| 3| 3| 5| 5| 4| 3| 9| 4| 1| 4| 3| 5| 4| 4| 4| 4| 5| 3| 5| 3| 5| 5| 5|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|     A      |
    25 PPM                                 | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Ear                                     |                                                       +                  |   1        |
                                           |__________________________________________________________________________|____________|
   Eye                                     |             +                                                            |   3        |
                                           |__________________________________________________________________________|____________|
   Harderian Gland                         |          +                                +                              |   5        |
      Adenoma                              |          X                                                               |          2 |
      Carcinoma                            |                                                                          |          1 |
      Bilateral, Adenoma                   |                                           X                              |          2 |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                                 X                        |          3 |
 __________________________________________________________________________________________________________________________________ 
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  72                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 7| 6| 6| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 5| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 1| 3| 0| 9| 3| 5| 3| 3| 3| 3| 3| 3| 3| 2| 1| 3| 6| 3| 3| 0| 3| 0|             
                                           | 3| 5| 3| 5| 4| 2| 9| 3| 4| 3| 3| 4| 3| 3| 4| 4| 8| 2| 3| 1| 5| 3| 3| 3| 0|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    100 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |__________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Gallbladder                             | +  +  +  +  +  +  A  +  M  +  M  +  +  +  +  I  +  A  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +|             
      Carcinoma                            |                   X                                                      |             
                                           |__________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +|             
      Carcinoma                            |                                                       X                  |             
      Lymphoma Malignant                   |                                     X                                    |             
                                           |__________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hepatocellular Carcinoma             |    X                                         X           X               |             
      Hepatocellular Carcinoma, Multiple   |                            X                                      X      |             
      Hepatocellular Adenoma               |          X                       X           X              X        X   |             
      Hepatocellular Adenoma, Multiple     |                         X                                               X|             
      Histiocytic Sarcoma                  |                                                                          |             
      Lymphoma Malignant                   |                X                                                         |             
                                           |__________________________________________________________________________|             
   Mesentery                               |                      +           +  +  +                    +           +|             
                                           |__________________________________________________________________________|             
   Oral Mucosa                             |                                                                          |             
                                           |__________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  73                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 7| 6| 6| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 5| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 1| 3| 0| 9| 3| 5| 3| 3| 3| 3| 3| 3| 3| 2| 1| 3| 6| 3| 3| 0| 3| 0|             
                                           | 3| 5| 3| 5| 4| 2| 9| 3| 4| 3| 3| 4| 3| 3| 4| 4| 8| 2| 3| 1| 5| 3| 3| 3| 0|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    100 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
                                           |__________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  M  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Tooth                                   | +  +     +  +              +  +     +  +              +        +        +|             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                X                                                         |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |__________________________________________________________________________|             
   Adrenal Cortex                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                X                                                         |             
                                           |__________________________________________________________________________|             
   Adrenal Medulla                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Adenoma                              |                         X                          X                     |             
                                           |__________________________________________________________________________|             
   Parathyroid Gland                       | +  +  +  +  M  +  +  +  +  M  +  M  +  M  +  M  +  M  +  +  M  +  +  M  +|             
                                           |__________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                X                                                         |             
                                           |__________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Follicular Cell, Carcinoma           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Epididymis                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Histiocytic Sarcoma                  |                                                                          |             
                                           |__________________________________________________________________________|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  74                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 7| 6| 6| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 5| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 1| 3| 0| 9| 3| 5| 3| 3| 3| 3| 3| 3| 3| 2| 1| 3| 6| 3| 3| 0| 3| 0|             
                                           | 3| 5| 3| 5| 4| 2| 9| 3| 4| 3| 3| 4| 3| 3| 4| 4| 8| 2| 3| 1| 5| 3| 3| 3| 0|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    100 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
   Penis                                   |                                                                          |             
                                           |__________________________________________________________________________|             
   Preputial Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hemangiosarcoma                      |       X                                                                  |             
                                           |__________________________________________________________________________|             
   Prostate                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                X                                                         |             
                                           |__________________________________________________________________________|             
   Seminal Vesicle                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                X                                                         |             
                                           |__________________________________________________________________________|             
   Testes                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |__________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Histiocytic Sarcoma                  |                                                                          |             
                                           |__________________________________________________________________________|             
   Lymph Node                              |                +                                                        +|             
      Iliac, Lymphoma Malignant            |                X                                                         |             
      Pancreatic, Lymphoma Malignant       |                                                                          |             
      Renal, Lymphoma Malignant            |                X                                                         |             
                                           |__________________________________________________________________________|             
   Lymph Node, Bronchial                   | +  M  +  +  +  +  +  +  +  +  +  +  +  +  M  +  M  +  +  +  M  +  M  +  +|             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Metastatic, Lung                 |                                                                          |             
      Lymphoma Malignant                   |                X                                                         |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mandibular                  | M  M  +  M  +  +  M  +  +  M  +  +  +  M  M  +  +  +  +  +  M  +  M  +  M|             
      Lymphoma Malignant                   |                X                                                         |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Histiocytic Sarcoma                  |                                                                          |             
      Lymphoma Malignant                   |                X                    X                                    |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mediastinal                 | +  +  +  +  +  +  M  +  M  +  +  +  +  +  M  +  +  +  +  +  M  +  +  +  +|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  75                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 7| 6| 6| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 5| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 1| 3| 0| 9| 3| 5| 3| 3| 3| 3| 3| 3| 3| 2| 1| 3| 6| 3| 3| 0| 3| 0|             
                                           | 3| 5| 3| 5| 4| 2| 9| 3| 4| 3| 3| 4| 3| 3| 4| 4| 8| 2| 3| 1| 5| 3| 3| 3| 0|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    100 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Lymphoma Malignant                   |                X                    X                                    |             
                                           |__________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                X                    X                                    |             
                                           |__________________________________________________________________________|             
   Thymus                                  | +  +  +  M  +  +  M  +  M  M  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |__________________________________________________________________________|             
   Mammary Gland                           | M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  +  M  M  M|             
                                           |__________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Subcutaneous Tissue, Hemangioma      |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |__________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Spinal Cord                             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |__________________________________________________________________________|             
   Larynx                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Carcinoma, Metastatic, Thyroid Gland |                                                                          |             
                                           |__________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Alveolar/Bronchiolar Adenoma         | X                 X                                                  X   |             
      Alveolar/Bronchiolar Carcinoma       |                                  X                             X         |             
      Carcinoma, Metastatic, Thyroid Gland |                                                                          |             
      Hepatocellular Carcinoma, Metastatic,|                                                                          |             
           Liver                           |    X                                                                     |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  76                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 7| 6| 6| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 6| 7| 5| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 1| 3| 0| 9| 3| 5| 3| 3| 3| 3| 3| 3| 3| 2| 1| 3| 6| 3| 3| 0| 3| 0|             
                                           | 3| 5| 3| 5| 4| 2| 9| 3| 4| 3| 3| 4| 3| 3| 4| 4| 8| 2| 3| 1| 5| 3| 3| 3| 0|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    100 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 RESPIRATORY SYSTEM - cont                 |                                                                          |             
                                           |                                                                          |             
      Histiocytic Sarcoma                  |                                                                          |             
      Lymphoma Malignant                   |                X                                                         |             
                                           |__________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Eye                                     |                                           +                              |             
                                           |__________________________________________________________________________|             
   Harderian Gland                         |                                           +                              |             
      Adenoma                              |                                           X                              |             
      Carcinoma                            |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                X                                                         |             
                                           |__________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                X                                                         |             
 __________________________________________|__________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Histiocytic Sarcoma                  |                                                                          |             
      Lymphoma Malignant                   |                X                    X                                    |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  77                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 5| 7| 7| 7| 6| 7| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 5| 7| 7| 7| 7| 7| 7| 7| 4|            |
                             DAY ON TEST   | 9| 3| 3| 3| 2| 3| 3| 3| 3| 6| 3| 3| 3| 3| 3| 3| 9| 3| 3| 3| 3| 3| 3| 3| 4|            |
                                           | 6| 4| 5| 5| 3| 5| 3| 4| 4| 8| 4| 3| 5| 3| 3| 3| 6| 5| 5| 4| 3| 4| 3| 5| 8|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|     A      |
    100 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Gallbladder                             | +  +  +  +  A  M  +  +  +  +  A  +  +  +  +  +  +  +  +  I  +  +  +  +  +|  41        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +  +  A  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +  +  A  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  47        |
      Carcinoma                            |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  +  A  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  47        |
      Carcinoma                            |                                                                          |          1 |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  +  A  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  47        |
                                           |__________________________________________________________________________|____________|
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Hepatocellular Carcinoma             | X        X  X        X                          X                        |          8 |
      Hepatocellular Carcinoma, Multiple   |                                                                          |          2 |
      Hepatocellular Adenoma               |    X                       X           X     X                           |          9 |
      Hepatocellular Adenoma, Multiple     |             X                                         X                 X|          5 |
      Histiocytic Sarcoma                  |                               X                                          |          1 |
      Lymphoma Malignant                   | X                                                                        |          2 |
                                           |__________________________________________________________________________|____________|
   Mesentery                               |       +  +              +                                         +      |  10        |
                                           |__________________________________________________________________________|____________|
   Oral Mucosa                             |                               M                                          |            |
                                           |__________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  78                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 5| 7| 7| 7| 6| 7| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 5| 7| 7| 7| 7| 7| 7| 7| 4|            |
                             DAY ON TEST   | 9| 3| 3| 3| 2| 3| 3| 3| 3| 6| 3| 3| 3| 3| 3| 3| 9| 3| 3| 3| 3| 3| 3| 3| 4|            |
                                           | 6| 4| 5| 5| 3| 5| 3| 4| 4| 8| 4| 3| 5| 3| 3| 3| 6| 5| 5| 4| 3| 4| 3| 5| 8|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|     A      |
    100 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
                                           |__________________________________________________________________________|____________|
   Tooth                                   | +     +        +     +  +        +  +        +     +        +     +      |  22        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   | X                                                                        |          2 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Adrenal Cortex                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   | X                                                                        |          2 |
                                           |__________________________________________________________________________|____________|
   Adrenal Medulla                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Adenoma                              |                                                                          |          2 |
                                           |__________________________________________________________________________|____________|
   Parathyroid Gland                       | M  +  +  +  M  +  +  +  +  +  M  M  +  +  M  +  +  +  +  M  +  M  M  +  +|  34        |
                                           |__________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Follicular Cell, Carcinoma           |                                                          X               |          1 |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  79                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 5| 7| 7| 7| 6| 7| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 5| 7| 7| 7| 7| 7| 7| 7| 4|            |
                             DAY ON TEST   | 9| 3| 3| 3| 2| 3| 3| 3| 3| 6| 3| 3| 3| 3| 3| 3| 9| 3| 3| 3| 3| 3| 3| 3| 4|            |
                                           | 6| 4| 5| 5| 3| 5| 3| 4| 4| 8| 4| 3| 5| 3| 3| 3| 6| 5| 5| 4| 3| 4| 3| 5| 8|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|     A      |
    100 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 GENITAL SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Epididymis                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Histiocytic Sarcoma                  |                               X                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Penis                                   | +                                                                        |   1        |
                                           |__________________________________________________________________________|____________|
   Preputial Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Hemangiosarcoma                      |                                  X                                       |          2 |
                                           |__________________________________________________________________________|____________|
   Prostate                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Seminal Vesicle                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Testes                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Histiocytic Sarcoma                  |                               X                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Lymph Node                              |                                           +                              |   3        |
      Iliac, Lymphoma Malignant            |                                           X                              |          2 |
      Pancreatic, Lymphoma Malignant       |                                           X                              |          1 |
      Renal, Lymphoma Malignant            |                                           X                              |          2 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Bronchial                   | +  +  +  +  +  +  M  M  +  M  +  +  M  +  +  +  +  +  M  +  +  +  +  +  +|  40        |
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |            |
          Metastatic, Lung                 |                               X                                          |          1 |
      Lymphoma Malignant                   | X                                         X                              |          3 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mandibular                  | +  +  M  +  +  +  +  M  +  M  M  M  M  +  +  +  M  +  +  +  +  M  +  +  +|  32        |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  80                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 5| 7| 7| 7| 6| 7| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 5| 7| 7| 7| 7| 7| 7| 7| 4|            |
                             DAY ON TEST   | 9| 3| 3| 3| 2| 3| 3| 3| 3| 6| 3| 3| 3| 3| 3| 3| 9| 3| 3| 3| 3| 3| 3| 3| 4|            |
                                           | 6| 4| 5| 5| 3| 5| 3| 4| 4| 8| 4| 3| 5| 3| 3| 3| 6| 5| 5| 4| 3| 4| 3| 5| 8|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|     A      |
    100 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
      Lymphoma Malignant                   | X                                         X                              |          3 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Histiocytic Sarcoma                  |                               X                                          |          1 |
      Lymphoma Malignant                   | X                                         X                              |          4 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mediastinal                 | M  +  +  +  +  +  M  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  M  +|  42        |
      Lymphoma Malignant                   |                                           X                              |          3 |
                                           |__________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   | X                                         X                              |          4 |
                                           |__________________________________________________________________________|____________|
   Thymus                                  | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  M  +|  42        |
      Lymphoma Malignant                   |                                           X                              |          1 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Mammary Gland                           | M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M|   1        |
                                           |__________________________________________________________________________|____________|
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Subcutaneous Tissue, Hemangioma      |                                                 X                        |          1 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Spinal Cord                             |    M                          M                                          |            |
 _____________________________________________________________________________________________________________________|            |
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  81                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 5| 7| 7| 7| 6| 7| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 5| 7| 7| 7| 7| 7| 7| 7| 4|            |
                             DAY ON TEST   | 9| 3| 3| 3| 2| 3| 3| 3| 3| 6| 3| 3| 3| 3| 3| 3| 9| 3| 3| 3| 3| 3| 3| 3| 4|            |
                                           | 6| 4| 5| 5| 3| 5| 3| 4| 4| 8| 4| 3| 5| 3| 3| 3| 6| 5| 5| 4| 3| 4| 3| 5| 8|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|     A      |
    100 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Larynx                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Carcinoma, Metastatic, Thyroid Gland |                                                          X               |          1 |
                                           |__________________________________________________________________________|____________|
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Alveolar/Bronchiolar Adenoma         |                         X                                                |          4 |
      Alveolar/Bronchiolar Carcinoma       |          X  X                 X        X                                 |          6 |
      Carcinoma, Metastatic, Thyroid Gland |                                                          X               |          1 |
      Hepatocellular Carcinoma, Metastatic,|                                                                          |            |
           Liver                           | X        X                                      X                        |          4 |
      Histiocytic Sarcoma                  |                               X                                          |          1 |
      Lymphoma Malignant                   | X                                         X                              |          3 |
                                           |__________________________________________________________________________|____________|
   Nose                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Eye                                     |                   +                                                      |   2        |
                                           |__________________________________________________________________________|____________|
   Harderian Gland                         |          +        +                          +        +                  |   5        |
      Adenoma                              |          X        X                                   X                  |          4 |
      Carcinoma                            |                                              X                           |          1 |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   | X                                                                        |          2 |
                                           |__________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Lymphoma Malignant                   |                                                                          |          1 |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 __________________________________________________________________________________________________________________________________ 
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                             Page  82                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 5| 7| 7| 7| 6| 7| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 5| 7| 7| 7| 7| 7| 7| 7| 4|            |
                             DAY ON TEST   | 9| 3| 3| 3| 2| 3| 3| 3| 3| 6| 3| 3| 3| 3| 3| 3| 9| 3| 3| 3| 3| 3| 3| 3| 4|            |
                                           | 6| 4| 5| 5| 3| 5| 3| 4| 4| 8| 4| 3| 5| 3| 3| 3| 6| 5| 5| 4| 3| 4| 3| 5| 8|            |
 _____________________________________________________________________________________________________________________      T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|     A      |
    100 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS - cont                   |                                                                          |            |
                                           |                                                                          |            |
      Histiocytic Sarcoma                  |                               X                                          |          1 |
      Lymphoma Malignant                   | X                                         X                              |          4 |
 __________________________________________________________________________________________________________________________________ 
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  83                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 6| 7| 7| 7| 7| 7| 5| 7| 6| 7| 7| 5| 7| 7| 7| 7| 7| 6| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 0| 3| 3| 2| 3| 3| 3| 3| 1| 3| 3| 9| 3| 2| 3| 3| 3| 0| 3| 3| 3| 3| 3|             
                                           | 3| 4| 2| 4| 4| 3| 4| 4| 0| 3| 6| 5| 4| 3| 4| 3| 3| 3| 4| 5| 5| 3| 4| 3| 4|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    400 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |__________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Gallbladder                             | +  +  A  +  +  +  +  +  A  +  +  +  +  A  +  +  +  M  +  A  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  A  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  A  +  +  +  +  +  A  +  +  +  +  A  +  +  +  +  +  A  +  +  +  +  +|             
      Lymphoma Malignant                   |                                                                         X|             
                                           |__________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  A  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Hemangiosarcoma                      |                                  X                                       |             
      Hepatoblastoma                       |                                                                          |             
      Hepatocellular Carcinoma             |       X                                X     X  X        X  X            |             
      Hepatocellular Adenoma               |    X                       X              X  X     X  X  X  X           X|             
      Hepatocellular Adenoma, Multiple     | X        X        X                 X                             X      |             
      Liposarcoma, Metastatic, Mesentery   |                                              X                           |             
      Lymphoma Malignant                   |                                                                          |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Mesentery                               |                         +  +        +     +  +     +           +        +|             
      Liposarcoma                          |                                              X                           |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +|             
      Liposarcoma, Metastatic, Mesentery   |                                              X                           |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  84                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 6| 7| 7| 7| 7| 7| 5| 7| 6| 7| 7| 5| 7| 7| 7| 7| 7| 6| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 0| 3| 3| 2| 3| 3| 3| 3| 1| 3| 3| 9| 3| 2| 3| 3| 3| 0| 3| 3| 3| 3| 3|             
                                           | 3| 4| 2| 4| 4| 3| 4| 4| 0| 3| 6| 5| 4| 3| 4| 3| 3| 3| 4| 5| 5| 3| 4| 3| 4|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    400 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
          Primary Site                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +|             
      Liposarcoma, Metastatic, Mesentery   |                                              X                           |             
                                           |__________________________________________________________________________|             
   Tooth                                   | +  +        +        +     +              +     +  +           +  +  +   |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Blood Vessel                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Metastatic, Lung                 |                         X                                                |             
      Carcinoma, Metastatic, Uncertain     |                                                                          |             
          Primary Site                     |                                                                          |             
      Hemangiosarcoma, Metastatic, Liver   |                                                                          |             
      Lymphoma Malignant                   |                                                                          |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |__________________________________________________________________________|             
   Adrenal Cortex                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
      Subcapsular, Adenoma                 |                                  X                                   X   |             
                                           |__________________________________________________________________________|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  85                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 6| 7| 7| 7| 7| 7| 5| 7| 6| 7| 7| 5| 7| 7| 7| 7| 7| 6| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 0| 3| 3| 2| 3| 3| 3| 3| 1| 3| 3| 9| 3| 2| 3| 3| 3| 0| 3| 3| 3| 3| 3|             
                                           | 3| 4| 2| 4| 4| 3| 4| 4| 0| 3| 6| 5| 4| 3| 4| 3| 3| 3| 4| 5| 5| 3| 4| 3| 4|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    400 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
   Adrenal Medulla                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +|             
      Adenoma                              |                                                                X         |             
                                           |__________________________________________________________________________|             
   Parathyroid Gland                       | +  M  M  +  M  +  +  +  +  +  +  M  M  A  M  +  +  +  +  M  +  M  +  M  I|             
                                           |__________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |__________________________________________________________________________|             
   Peritoneum                              |                                                                          |             
      Hemangiosarcoma, Metastatic, Liver   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Epididymis                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                                                          |             
                                           |__________________________________________________________________________|             
   Preputial Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Prostate                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Seminal Vesicle                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Liposarcoma, Metastatic, Mesentery   |                                              X                           |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Testes                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Interstitial Cell, Adenoma           |       X                          X                                   X   |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  86                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 6| 7| 7| 7| 7| 7| 5| 7| 6| 7| 7| 5| 7| 7| 7| 7| 7| 6| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 0| 3| 3| 2| 3| 3| 3| 3| 1| 3| 3| 9| 3| 2| 3| 3| 3| 0| 3| 3| 3| 3| 3|             
                                           | 3| 4| 2| 4| 4| 3| 4| 4| 0| 3| 6| 5| 4| 3| 4| 3| 3| 3| 4| 5| 5| 3| 4| 3| 4|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    400 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
                                           |__________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Lymph Node                              |                                                                          |             
      Renal, Lymphoma Malignant            |                                                                          |             
                                           |__________________________________________________________________________|             
   Lymph Node, Bronchial                   | +  M  +  +  +  +  +  +  +  M  M  +  M  A  M  +  +  +  M  +  +  +  +  +  +|             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Metastatic, Lung                 |                         X                                                |             
      Liposarcoma, Metastatic, Mesentery   |                                              X                           |             
      Lymphoma Malignant                   |                                                                          |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mandibular                  | M  +  M  +  +  M  +  M  M  +  +  M  M  A  +  +  M  M  +  +  M  +  +  +  +|             
      Liposarcoma, Metastatic, Mesentery   |                                              X                           |             
      Lymphoma Malignant                   |                                              X                           |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +|             
      Liposarcoma, Metastatic, Mesentery   |                                              X                           |             
      Lymphoma Malignant                   |                                                                          |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Lymph Node, Mediastinal                 | +  +  +  +  +  +  +  M  +  M  M  M  +  A  +  M  +  +  M  M  +  +  +  +  +|             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Metastatic, Lung                 |                                                                          |             
      Lymphoma Malignant                   |                                                                          |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +|             
      Hemangiosarcoma                      |                                                                          |             
      Lymphoma Malignant                   |                                                                          |             
                                           |__________________________________________________________________________|             
   Thymus                                  | +  +  +  +  M  M  +  +  +  +  +  M  M  A  +  +  +  +  +  +  I  M  +  +  +|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  87                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 6| 7| 7| 7| 7| 7| 5| 7| 6| 7| 7| 5| 7| 7| 7| 7| 7| 6| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 0| 3| 3| 2| 3| 3| 3| 3| 1| 3| 3| 9| 3| 2| 3| 3| 3| 0| 3| 3| 3| 3| 3|             
                                           | 3| 4| 2| 4| 4| 3| 4| 4| 0| 3| 6| 5| 4| 3| 4| 3| 3| 3| 4| 5| 5| 3| 4| 3| 4|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    400 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Carcinoma, Metastatic, Uncertain     |                                                                          |             
          Primary Site                     |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |__________________________________________________________________________|             
   Mammary Gland                           | M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M|             
                                           |__________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |__________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Skeletal Muscle                         |                                              +                           |             
      Liposarcoma, Metastatic, Mesentery   |                                              X                           |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |__________________________________________________________________________|             
   Larynx                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Alveolar/Bronchiolar Adenoma         |                                                       X                  |             
      Alveolar/Bronchiolar Carcinoma       | X                       X        X                       X        X      |             
      Carcinoma, Metastatic, Uncertain     |                                                                          |             
          Primary Site                     |                                                                          |             
      Hemangiosarcoma, Metastatic, Liver   |                                                                          |             
      Hepatocellular Carcinoma, Metastatic,|                                                                          |             
           Liver                           |       X                                         X                        |             
      Liposarcoma, Metastatic, Mesentery   |                                              X                           |             
      Lymphoma Malignant                   |                                              X                           |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  88                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 6| 7| 7| 7| 7| 7| 5| 7| 6| 7| 7| 5| 7| 7| 7| 7| 7| 6| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 0| 3| 3| 2| 3| 3| 3| 3| 1| 3| 3| 9| 3| 2| 3| 3| 3| 0| 3| 3| 3| 3| 3|             
                                           | 3| 4| 2| 4| 4| 3| 4| 4| 0| 3| 6| 5| 4| 3| 4| 3| 3| 3| 4| 5| 5| 3| 4| 3| 4|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    400 PPM                                | 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 RESPIRATORY SYSTEM - cont                 |                                                                          |             
                                           |                                                                          |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
      Mediastinum, Alveolar/Bronchiolar    |                                                                          |             
          Carcinoma, Metastatic, Lung      |                         X                                                |             
                                           |__________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Pleura                                  |                                                                          |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Eye                                     |                                                    +                     |             
                                           |__________________________________________________________________________|             
   Harderian Gland                         |          +                                         +              +      |             
      Adenoma                              |          X                                                               |             
      Carcinoma                            |                                                    X                     |             
      Bilateral, Adenoma                   |                                                                   X      |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |__________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +|             
      Carcinoma, Metastatic, Uncertain     |                                                                          |             
          Primary Site                     |                                                                          |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
                                           |__________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
 __________________________________________|__________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant                   |                                              X                          X|             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  89                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 6| 7| 7| 4| 7| 7| 6| 7| 7| 7| 7| 7| 6| 7| 7| 4| 7| 5| 7| 6| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 1| 3| 6| 3| 3| 3| 3| 3| 3| 3| 3| 9| 3| 3| 6| 3| 5| 3| 2| 3| 3|            |
                                           | 5| 4| 3| 4| 8| 1| 7| 3| 3| 4| 3| 3| 4| 3| 4| 2| 4| 3| 9| 4| 2| 3| 2| 3| 4|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|     A      |
    400 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Gallbladder                             | +  +  +  A  A  A  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  A  +  +|  40        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  I  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  +  A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  46        |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +  A  A  A  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  A  +  +|  43        |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  43        |
      Lymphoma Malignant                   |                                                                   X      |          2 |
                                           |__________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  46        |
                                           |__________________________________________________________________________|____________|
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Hemangiosarcoma                      |       X                                                                  |          2 |
      Hepatoblastoma                       |             X                                                            |          1 |
      Hepatocellular Carcinoma             |       X                 X                    X              X     X      |         11 |
      Hepatocellular Adenoma               |    X     X  X  X                 X  X     X                       X      |         17 |
      Hepatocellular Adenoma, Multiple     |                               X        X        X              X     X   |         10 |
      Liposarcoma, Metastatic, Mesentery   |                                                                          |          1 |
      Lymphoma Malignant                   |                                                             X            |          1 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                                              X                           |          1 |
                                           |__________________________________________________________________________|____________|
   Mesentery                               |                +        +     +  +           +     +           +         |  15        |
      Liposarcoma                          |                                                                          |          1 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                                              X                           |          1 |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  90                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 6| 7| 7| 4| 7| 7| 6| 7| 7| 7| 7| 7| 6| 7| 7| 4| 7| 5| 7| 6| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 1| 3| 6| 3| 3| 3| 3| 3| 3| 3| 3| 9| 3| 3| 6| 3| 5| 3| 2| 3| 3|            |
                                           | 5| 4| 3| 4| 8| 1| 7| 3| 3| 4| 3| 3| 4| 3| 4| 2| 4| 3| 9| 4| 2| 3| 2| 3| 4|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|     A      |
    400 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Liposarcoma, Metastatic, Mesentery   |                                                                          |          1 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                         X                    X                           |          2 |
                                           |__________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                         X                                                |          1 |
                                           |__________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
      Liposarcoma, Metastatic, Mesentery   |                                                                          |          1 |
                                           |__________________________________________________________________________|____________|
   Tooth                                   | +     +        +        +     +  +     +  +                    +     +   |  21        |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                         X                                                |          1 |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Blood Vessel                            |                                  +                                       |   1        |
                                           |__________________________________________________________________________|____________|
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |            |
          Metastatic, Lung                 |                                                                          |          1 |
      Carcinoma, Metastatic, Uncertain     |                                                                          |            |
          Primary Site                     |                                              X                           |          1 |
      Hemangiosarcoma, Metastatic, Liver   |       X                                                                  |          1 |
      Lymphoma Malignant                   |                                                             X            |          1 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                         X                                                |          1 |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  91                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 6| 7| 7| 4| 7| 7| 6| 7| 7| 7| 7| 7| 6| 7| 7| 4| 7| 5| 7| 6| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 1| 3| 6| 3| 3| 3| 3| 3| 3| 3| 3| 9| 3| 3| 6| 3| 5| 3| 2| 3| 3|            |
                                           | 5| 4| 3| 4| 8| 1| 7| 3| 3| 4| 3| 3| 4| 3| 4| 2| 4| 3| 9| 4| 2| 3| 2| 3| 4|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|     A      |
    400 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Adrenal Cortex                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                         X                                                |          1 |
      Subcapsular, Adenoma                 |          X                                X                              |          4 |
                                           |__________________________________________________________________________|____________|
   Adrenal Medulla                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                         X                                                |          1 |
                                           |__________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Adenoma                              |                X                                                         |          2 |
                                           |__________________________________________________________________________|____________|
   Parathyroid Gland                       | M  +  +  +  M  +  M  +  +  +  +  +  +  +  +  +  +  M  +  M  M  +  M  +  +|  32        |
                                           |__________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
                                           |__________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Peritoneum                              |       +                                                                  |   1        |
      Hemangiosarcoma, Metastatic, Liver   |       X                                                                  |          1 |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Epididymis                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                                             X            |          1 |
                                           |__________________________________________________________________________|____________|
   Preputial Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Prostate                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  92                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 6| 7| 7| 4| 7| 7| 6| 7| 7| 7| 7| 7| 6| 7| 7| 4| 7| 5| 7| 6| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 1| 3| 6| 3| 3| 3| 3| 3| 3| 3| 3| 9| 3| 3| 6| 3| 5| 3| 2| 3| 3|            |
                                           | 5| 4| 3| 4| 8| 1| 7| 3| 3| 4| 3| 3| 4| 3| 4| 2| 4| 3| 9| 4| 2| 3| 2| 3| 4|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|     A      |
    400 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 GENITAL SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
   Seminal Vesicle                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Liposarcoma, Metastatic, Mesentery   |                                                                          |          1 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                                              X                           |          1 |
                                           |__________________________________________________________________________|____________|
   Testes                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Interstitial Cell, Adenoma           |                                                                          |          3 |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
                                           |__________________________________________________________________________|____________|
   Lymph Node                              |                                                             +            |   1        |
      Renal, Lymphoma Malignant            |                                                             X            |          1 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Bronchial                   | +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +|  41        |
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |            |
          Metastatic, Lung                 |                                                       X                  |          2 |
      Liposarcoma, Metastatic, Mesentery   |                                                                          |          1 |
      Lymphoma Malignant                   |                                                             X            |          1 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                         X                    X                           |          2 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mandibular                  | M  M  M  M  +  M  M  M  M  +  M  M  +  M  M  +  M  +  M  M  +  +  M  +  M|  22        |
      Liposarcoma, Metastatic, Mesentery   |                                                                          |          1 |
      Lymphoma Malignant                   |                                                             X            |          2 |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  | +  +  +  M  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  47        |
      Liposarcoma, Metastatic, Mesentery   |                                                                          |          1 |
      Lymphoma Malignant                   |                                                             X     X      |          2 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                         X                    X                           |          2 |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  93                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 6| 7| 7| 4| 7| 7| 6| 7| 7| 7| 7| 7| 6| 7| 7| 4| 7| 5| 7| 6| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 1| 3| 6| 3| 3| 3| 3| 3| 3| 3| 3| 9| 3| 3| 6| 3| 5| 3| 2| 3| 3|            |
                                           | 5| 4| 3| 4| 8| 1| 7| 3| 3| 4| 3| 3| 4| 3| 4| 2| 4| 3| 9| 4| 2| 3| 2| 3| 4|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|     A      |
    400 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Lymph Node, Mediastinal                 | +  +  +  +  +  +  M  M  +  M  +  +  +  +  M  +  M  +  +  +  +  +  +  M  M|  35        |
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |            |
          Metastatic, Lung                 |          X                                                               |          1 |
      Lymphoma Malignant                   |                                                             X            |          1 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                         X                    X                           |          2 |
                                           |__________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Hemangiosarcoma                      |       X     X                                                            |          2 |
      Lymphoma Malignant                   |                                                             X            |          1 |
                                           |__________________________________________________________________________|____________|
   Thymus                                  | +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  M  +|  40        |
      Carcinoma, Metastatic, Uncertain     |                                                                          |            |
          Primary Site                     |                                              X                           |          1 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Mammary Gland                           | M  M  +  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M|   1        |
                                           |__________________________________________________________________________|____________|
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Skeletal Muscle                         |                                              +                           |   2        |
      Liposarcoma, Metastatic, Mesentery   |                                                                          |          1 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                                              X                           |          1 |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  94                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 6| 7| 7| 4| 7| 7| 6| 7| 7| 7| 7| 7| 6| 7| 7| 4| 7| 5| 7| 6| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 1| 3| 6| 3| 3| 3| 3| 3| 3| 3| 3| 9| 3| 3| 6| 3| 5| 3| 2| 3| 3|            |
                                           | 5| 4| 3| 4| 8| 1| 7| 3| 3| 4| 3| 3| 4| 3| 4| 2| 4| 3| 9| 4| 2| 3| 2| 3| 4|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|     A      |
    400 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 NERVOUS SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Larynx                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
                                           |__________________________________________________________________________|____________|
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Alveolar/Bronchiolar Adenoma         |                                                                   X      |          2 |
      Alveolar/Bronchiolar Carcinoma       | X     X  X                                            X  X     X  X      |         12 |
      Carcinoma, Metastatic, Uncertain     |                                                                          |            |
          Primary Site                     |                                              X                           |          1 |
      Hemangiosarcoma, Metastatic, Liver   |       X                                                                  |          1 |
      Hepatocellular Carcinoma, Metastatic,|                                                                          |            |
           Liver                           |       X                                      X                    X      |          5 |
      Liposarcoma, Metastatic, Mesentery   |                                                                          |          1 |
      Lymphoma Malignant                   |                                                             X            |          2 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                         X                    X                           |          2 |
      Mediastinum, Alveolar/Bronchiolar    |                                                                          |            |
          Carcinoma, Metastatic, Lung      |                                                       X                  |          2 |
                                           |__________________________________________________________________________|____________|
   Nose                                    | +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
                                           |__________________________________________________________________________|____________|
   Pleura                                  |                                              +                           |   1        |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                                              X                           |          1 |
                                           |__________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  48        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |__________________________________________________________________________|____________|
 _____________________________________________________________________________________________________________________|____________|
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                             Page  95                                                               
                                                                                                                                   
NTP Experiment-Test: 93026-06                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04  
Study Type: CHRONIC                                              DECALIN                                          Date: 04/11/02    
Route: RESPIRATORY EXPOSURE WHOLE BODY                                                                            Time: 09:23:18    
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 6| 7| 7| 4| 7| 7| 6| 7| 7| 7| 7| 7| 6| 7| 7| 4| 7| 5| 7| 6| 7| 7|            |
                             DAY ON TEST   | 3| 3| 3| 3| 1| 3| 6| 3| 3| 3| 3| 3| 3| 3| 3| 9| 3| 3| 6| 3| 5| 3| 2| 3| 3|            |
                                           | 5| 4| 3| 4| 8| 1| 7| 3| 3| 4| 3| 3| 4| 3| 4| 2| 4| 3| 9| 4| 2| 3| 2| 3| 4|            |
 __________________________________________|__________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|     T      |
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|     A      |
    400 PPM                                | 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5|     L      |
                                           | 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0|            |
 _____________________________________________________________________________________________________________________|____________|
 SPECIAL SENSES SYSTEM - cont              |                                                                          |            |
                                           |                                                                          |            |
   Eye                                     |                                                                          |   1        |
                                           |__________________________________________________________________________|____________|
   Harderian Gland                         |                   +        +                                             |   5        |
      Adenoma                              |                   X                                                      |          2 |
      Carcinoma                            |                                                                          |          1 |
      Bilateral, Adenoma                   |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |__________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
      Carcinoma, Metastatic, Uncertain     |                                                                          |            |
          Primary Site                     |                                              X                           |          1 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                         X                                                |          1 |
                                           |__________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  49        |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|  50        |
      Lymphoma Malignant                   |                                                             X     X      |          4 |
 __________________________________________________________________________________________________________________________________ 
                                                                                                                                    
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page  96                                                               
                                                                                                                                   
                                  ------------------------------------------------------------                                      
                                  ----------              END OF REPORT             ----------                                      
                                  ------------------------------------------------------------                                      
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.