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TDMS Study 96001-05 Pathology Tables

NTP  EXP/TEST: 96001-05                           STODDARD SOLVENT (TYPE IIC)                                     PAGE: 1
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 01/08/03
ROUTE: RESPIRATORY EXPOSURE WHOLE BODY                                                                            TIME: 11:58:18

                                                         EIS REPORT 03
                                                           FINAL/RATS


       FACILITY:  Battelle Northwest

       NTP C#:  C96001

       CONTRACT NUMBER:  NO1-ES-75410

       CAS NUMBER:  64742-88-7

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 96001-05                           STODDARD SOLVENT (TYPE IIC)                                     PAGE: 2
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 01/08/03
ROUTE: RESPIRATORY EXPOSURE WHOLE BODY                      EISRPT03                                              TIME: 11:58:18
----------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: F 344-RATS                 SEX: FEMALE      WEEK ON DOSE: 105    FIRST DOSE: 01/18/99
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 CONTROL            50     87.1    6.3        36    361.5   38.0                     36    274.6   37.8

 550     MG/M3      50     86.8    6.4        30    359.0   40.6        99.3         30    272.6   40.1

 1100    MG/M3      50     86.7    6.5        32    366.5   39.0       101.3         32    280.3   39.6

 2200    MG/M3      50     86.7    6.6        25    370.8   43.2       102.5         25    283.9   41.3




----------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: F 344-RATS                 SEX: MALE        WEEK ON DOSE: 105    FIRST DOSE: 01/18/99
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 CONTROL            50    105.2    8.7        29    524.8   53.4                     29    420.4   48.1

 138     MG/M3      50    103.4    8.8        19    502.4   44.7        95.7         19    401.7   45.7

 550     MG/M3      50    103.9    8.5        21    511.5   49.6        97.4         21    406.7   49.0

 1100    MG/M3      50    103.6    8.8        16    502.7   49.8        95.7         16    399.1   50.7

                                               -----------------------------------
                                               ---------- END-OF-REPORT ----------
                                               -----------------------------------