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TDMS Study 96001-06 Pathology Tables

NTP  EXP/TEST: 96001-06                           STODDARD SOLVENT (TYPE IIC)                                     PAGE: 1
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 09/25/02
ROUTE: RESPIRATORY EXPOSURE WHOLE BODY                                                                            TIME: 11:41:10

                                                         EIS REPORT 03
                                                         FINAL #1 MICE


       FACILITY:  Battelle Northwest

       NTP C#:  C96001

       CONTRACT NUMBER:  NO1-ES-75410

       CAS NUMBER:  64742-88-7

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 96001-06                           STODDARD SOLVENT (TYPE IIC)                                     PAGE: 2
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 09/25/02
ROUTE: RESPIRATORY EXPOSURE WHOLE BODY                      EISRPT03                                              TIME: 11:41:10
----------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: B6C3F1-MICE                SEX: FEMALE      WEEK ON DOSE: 105    FIRST DOSE: 12/21/98
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 CONTROL            50     18.0    1.1        36     48.5    7.6                     36     30.5    7.6

 550     MG/M3      50     18.2    1.0        34     51.5    9.7       106.1         34     33.3    9.8

 1100    MG/M3      50     18.3    1.1        27     54.5    9.5       112.3         27     36.4    9.7

 2200    MG/M3      50     17.9    1.1        34     50.0    8.5       103.0         34     32.0    8.7




----------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: B6C3F1-MICE                SEX: MALE        WEEK ON DOSE: 105    FIRST DOSE: 12/21/98
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 CONTROL            50     21.7    1.2        34     48.9    5.9                     34     27.3    5.5

 550     MG/M3      50     21.5    1.1        32     49.5    5.4       101.2         32     27.9    5.3

 1100    MG/M3      50     21.6    1.2        27     47.5    6.1        97.1         27     25.8    5.5

 2200    MG/M3      50     21.6    1.4        32     46.8    5.6        95.7         32     25.1    5.4

                                               -----------------------------------
                                               ---------- END-OF-REPORT ----------
                                               -----------------------------------