National Toxicology Program

National Toxicology Program
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TDMS Study 96007-03 Pathology Tables

NTP  EXP/TEST: 96007-03                    TOXIC EQUIVALENCY FACTOR EVALUATION (TCDD)                             PAGE: 1
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 11/25/02
ROUTE: GAVAGE                                                                                                     TIME: 11:35:48

                                                         EIS REPORT 03


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  96007G

       CONTRACT NUMBER:  NO1-ES-75411

       CAS NUMBER:  1746-01-6

       ANIMAL SUPPLIER:  HARLAN SPRAGUE-DAWLEY

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 96007-03                    TOXIC EQUIVALENCY FACTOR EVALUATION (TCDD)                             PAGE: 2
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 11/25/02
ROUTE: GAVAGE                                               EISRPT03                                              TIME: 11:35:48
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 SPECIES-STRAIN: SD-RATS                    SEX: FEMALE      WEEK ON DOSE: 105    FIRST DOSE: 06/01/98
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 NG/KG            98    176.5    7.7        25    373.8   51.8                     25    199.1   48.8

 3 NG/KG            98    175.2    6.8        21    375.6   44.5       100.4         21    201.1   44.0

 10 NG/KG           98    175.1    7.7        23    377.5   56.5       100.9         23    200.4   54.3

 22 NG/KG           98    174.8    7.2        19    362.3   54.1        96.9         19    186.7   49.9

 46 NG/KG           98    174.8    8.7        22    339.4   41.0        90.7         22    167.1   39.9

 100     NG/KG      98    176.0    7.2        21    303.7   26.2        81.2         21    127.0   26.4

 100 NG/ KG/STOP    50    173.9    8.5        21    340.0   31.1        90.9         21    164.7   31.7

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