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TDMS Study 96007-05 Pathology Tables

NTP  EXP/TEST: 96007-05                    TOXIC EQUIVALENCY FACTOR EVALUATION(PECDF)                             PAGE: 1
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 07/14/03
ROUTE: GAVAGE                                                                                                     TIME: 14:23:13

                                                         EIS REPORT 03


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  96007F

       CONTRACT NUMBER:  NO1-ES-75411

       CAS NUMBER:  57117-31-4

       ANIMAL SUPPLIER:  HARLAN SPRAGUE-DAWLEY

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 96007-05                    TOXIC EQUIVALENCY FACTOR EVALUATION(PECDF)                             PAGE: 2
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 07/14/03
ROUTE: GAVAGE                                               EISRPT03                                              TIME: 14:23:13
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 SPECIES-STRAIN: SD-RATS                    SEX: FEMALE      WEEK ON DOSE: 104    FIRST DOSE: 04/07/99
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 NG/KG            98    187.4   11.1        25    359.3   44.1                     25    171.2   43.4

 6 NG/KG            98    189.6   13.7        22    386.1   54.2       107.4         22    198.6   55.0

 20 NG/KG           98    188.3   11.5        24    363.2   45.9       101.0         24    173.1   46.2

 44 NG/KG           98    187.8   12.8        25    330.0   39.7        91.8         25    147.1   38.0

 92 NG/KG           98    187.4   11.5        20    341.8   44.5        95.1         20    152.2   42.5

 200     NG/KG      98    188.2   12.4        23    314.9   36.0        87.6         23    124.4   31.1

 200 NG/ KG STOP    50    187.1   13.0        15    337.3   37.6        93.8         15    150.1   37.0

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