National Toxicology Program

National Toxicology Program
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TDMS Study 96010-03 Pathology Tables

NTP  EXP/TEST: 96010-03                 WATER DISINFECTION BYPRODUCTS (SODIUM CHLORATE)                           PAGE: 1
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 05/27/03
ROUTE: DOSED WATER                                                                                                TIME: 13:19:36

                                                         EIS REPORT 03
                                                          FINAL#1/RATS


       FACILITY:  Southern Research Institute

       NTP C#:  96010A

       CONTRACT NUMBER:  N01-ES-85420

       CAS NUMBER:  7775-09-9

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 96010-03                 WATER DISINFECTION BYPRODUCTS (SODIUM CHLORATE)                           PAGE: 2
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 05/27/03
ROUTE: DOSED WATER                                          EISRPT03                                              TIME: 13:19:36
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 SPECIES-STRAIN: F 344-RATS                 SEX: FEMALE      WEEK ON DOSE: 105    FIRST DOSE: 09/16/98
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             50     91.3    6.8        37    342.5   33.2                     37    251.2   35.2

 125 MG/L           50     90.7    7.8        34    356.6   37.1       104.1         34    266.0   36.7

 1000MG/L           50     91.0    7.1        32    358.6   19.7       104.7         32    268.5   23.0

 2000MG/L           50     89.1    6.4        40    340.9   36.0        99.5         40    252.4   36.1




----------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: F 344-RATS                 SEX: MALE        WEEK ON DOSE: 105    FIRST DOSE: 09/16/98
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             50    102.1   10.2        36    489.6   49.4                     36    386.6   44.4

 125 MG/L           50    103.0    9.8        27    500.5   36.9       102.2         27    397.4   38.0

 1000MG/L           50    102.9    9.8        31    499.7   47.7       102.0         31    399.6   48.4

 2000MG/L           50    102.7    9.7        28    495.6   44.7       101.2         28    391.7   47.4

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