NCTR Study 211601 Pathology Tables
NCTR EXP/TEST: 211601 PAGE: 1
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:31.4
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DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 0| 3| 6| 0| 5| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 0| 6| 7| 5| 0| 5| 7| 8| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 8| 3| 2| 2| 0| 4| 2| 4| 0| 4| 5| 5| 5| 5| 6| 6| 5| 5| 5| 6| 6| 6| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| S R R|
| 0| 3| 8| 6| 7| 8| 0| 1| 1| 8| 9| 9| 9| 9| 2| 3| 2| 3| 3| 6| 6| 5| 9| 9| 9| U V I|
CONTRL F2YR 01 1 | 1| 8| 8| 3| 9| 2| 4| 0| 2| 9| 1| 2| 3| 4| 9| 0| 9| 0| 1| 6| 7| 3| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
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ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + M + + + + + + + + + + + + + + + + | |
HYPERKERATOSIS | 2 | |
ULCER | 3 | |
GALLBLADDER | + + + A + + + + M + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1| |
INTESTINE LARGE | + + + + + A + + A + + + + + + + + + + + + + + + + | |
INTESTINE LARGE,CECUM | + + A M + A + A A + + + + + + + + + + + + A + + + | |
HYPERPLASIA,LYMPHOID | | |
INTESTINE LARGE,COLON | + + + + + A + + A + + + + + + + + + + + + + + + + | |
INTESTINE LARGE,RECTUM | + + + + + A + A A + + + + + + + + + + + + + + + + | |
EROSION | | |
INTESTINE SMALL | + + A A + A A + A A + + + + + + + + + + + A + + + | |
INTESTINE SMALL,DUODENUM | + + A A + A A A A A + + + + + + + + + + + A + + + | |
INTESTINE SMALL,ILEUM | + + A A + A A A A A + + + + + + + + + + + A + + + | |
HYPERPLASIA,LYMPHOID | 2 | |
INTESTINE SMALL,JEJUNUM | + + A A + A A + A A + + + + + + + + + + + A + + + | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BASOPHILIC FOCUS | | |
HEMATOPOIETIC CELL PROLIFERATION | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 2 1 1 2 1| |
INFLAMMATION | 1 | |
NECROSIS | 1 1 2 1 1 1 1 1 1 1 1 1| |
NECROSIS,COAGULATIVE | 2 | |
TENSION LIPOIDOSIS | X X X X X X | |
VACUOLIZATION CYTOPLASMIC | 1 1 1 1 1 1 1 1| |
MESENTERY | + | |
PANCREAS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | | |
FOCAL CELLULAR CHANGE | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 1 1 1 1 1 1 1 1 1 1| |
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,DUCT | 3 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 2 2 1 1 1 2 2 1 1 1 1| |
STOMACH | + + + + + A + + + + + + + + + + + + + + + + + + + | |
STOMACH,FORESTOMACH | + + + + + A + + + + + + + + + + + + + + + + + + + | |
STOMACH,GLANDULAR | + + + + + A + + + + + + + + + + + + + + + + + + + | |
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+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 2
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:31.5
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DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 0| 3| 6| 0| 5| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 0| 6| 7| 5| 0| 5| 7| 8| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 8| 3| 2| 2| 0| 4| 2| 4| 0| 4| 5| 5| 5| 5| 6| 6| 5| 5| 5| 6| 6| 6| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| S R R|
| 0| 3| 8| 6| 7| 8| 0| 1| 1| 8| 9| 9| 9| 9| 2| 3| 2| 3| 3| 6| 6| 5| 9| 9| 9| U V I|
CONTRL F2YR 01 1 | 1| 8| 8| 3| 9| 2| 4| 0| 2| 9| 1| 2| 3| 4| 9| 0| 9| 0| 1| 6| 7| 3| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
CRYSTALS | | |
CYST | | |
DEGENERATION,HYALINE | | |
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,MAST CELL | 2 | |
POLYARTERITIS | | |
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CARDIOVASCULAR SYSTEM
BLOOD VESSEL | M M + M + + M + + M + M + + + + + + + + + + + + + | |
BLOOD VESSEL,AORTA | M M + M + + M + + M + M + + + + + + + + + + + + + | |
HEART | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DEGENERATION | 1 | |
INFLAMMATION | 4 | |
POLYARTERITIS | | |
THROMBUS | 4 | |
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ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + M + + M + + + + + + + + + + + + + + + | |
ACCESSORY ADRENAL CORTICAL NODULE | | |
ADRENAL GLAND,CORTEX | + + + + + + M + + M + + + + + + + + + + + + + + + | |
ECTOPIC TISSUE | X | |
HYPERPLASIA,SPINDLE CELL | 1 3 2 2 1 2 2 2 2 2 3 2 2 2 2 2 2 3 2 2| |
THROMBUS | 2 | |
VACUOLIZATION CYTOPLASMIC | | |
ADRENAL GLAND,MEDULLA | + + + + + + M + + M + + + + + + + + + + + + + + + | |
VACUOLIZATION CYTOPLASMIC | 2 | |
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
PARATHYROID GLAND | + M + M + + + M M + + M + + + + + + + + + M + + + | |
ECTOPIC THYMUS | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 | |
VACUOLIZATION CYTOPLASMIC | | |
PITUITARY GLAND | + + + M + + + + M + + + + + + + + + + + + + + + + | |
HYPERPLASIA,PARS DISTALIS | 1 3 1 | |
THYROID GLAND | + + + + + + + + M + + + + + + + + + + + + + + + + | |
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+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 3
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:31.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 0| 3| 6| 0| 5| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 0| 6| 7| 5| 0| 5| 7| 8| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 8| 3| 2| 2| 0| 4| 2| 4| 0| 4| 5| 5| 5| 5| 6| 6| 5| 5| 5| 6| 6| 6| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| S R R|
| 0| 3| 8| 6| 7| 8| 0| 1| 1| 8| 9| 9| 9| 9| 2| 3| 2| 3| 3| 6| 6| 5| 9| 9| 9| U V I|
CONTRL F2YR 01 1 | 1| 8| 8| 3| 9| 2| 4| 0| 2| 9| 1| 2| 3| 4| 9| 0| 9| 0| 1| 6| 7| 3| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
DEGENERATION | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1| |
ULTIMOBRANCHIAL CYST | 3 2 2 2 2 3| |
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GENERAL BODY SYSTEM
TISSUE NOS | + | |
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GENITAL SYSTEM
CLITORAL GLAND | M + + M + + + M + + M + + + + + + + + + + + + + + | |
ATROPHY | 4 4 3 3 4 4 4 2 3 4 3 2 4 3 4 4 3 4| |
OVARY | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | X X X X X X X X X X X X X X X X X X | |
CONGESTION | 2 | |
CYST | X X X X X | |
CYST,PERIOVARIAN TISSUE | X X X X X X | |
HEMATOCYST | X X | |
HYPERPLASIA,ADENOMATOUS | 4 4 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
UTERUS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | | |
ATROPHY | 3 4 | |
DILATATION | 3 | |
FIBROSIS | | |
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 1 2 2 2 3 3 3 3 3 3 2 2 2 3 2 1 2 3| |
PROLAPSE | | |
VAGINA | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 4 | |
DYSPLASIA | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
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HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + A + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | 3 3 | |
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+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 4
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:31.8
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DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 0| 3| 6| 0| 5| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 0| 6| 7| 5| 0| 5| 7| 8| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 8| 3| 2| 2| 0| 4| 2| 4| 0| 4| 5| 5| 5| 5| 6| 6| 5| 5| 5| 6| 6| 6| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| S R R|
| 0| 3| 8| 6| 7| 8| 0| 1| 1| 8| 9| 9| 9| 9| 2| 3| 2| 3| 3| 6| 6| 5| 9| 9| 9| U V I|
CONTRL F2YR 01 1 | 1| 8| 8| 3| 9| 2| 4| 0| 2| 9| 1| 2| 3| 4| 9| 0| 9| 0| 1| 6| 7| 3| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
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HEMATOPOIETIC SYSTEM
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + M + + + + + + + + + + + + + | |
HEMORRHAGE | | |
HYPERPLASIA,LYMPHOID | 2 2 2 2 | |
LYMPH NODE,MESENTERIC | + + + M + + + + + + + M + + + + + + + + + + + + + | |
ATROPHY | 2 | |
HEMORRHAGE | | |
HYPERPLASIA,LYMPHOID | 2 2 | |
SPLEEN | M + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 3 | |
HEMATOPOIETIC CELL PROLIFERATION | 3 3 3 | |
HYPERPLASIA,LYMPHOID | 2 2 2 1 3 | |
THYMUS | M M + M + + + + + + + + + + + + + + M + + + + + + | |
ATROPHY,CORTEX | 4 3 3 4 3 3 3 3 4 3 3 3 4 3 4 3 2 | |
CONGESTION | 2 | |
ECTOPIC PARATHYROID GLAND | X | |
HYPERPLASIA,LYMPHOID,MEDULLA | 2 2 1 2 2 3 3| |
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INTEGUMENTARY SYSTEM
MAMMARY GLAND | M + + + + + + + A + + + + + + + + M + + M + + + + | |
HYPERPLASIA | 2 | |
INFLAMMATION | | |
LACTATION | 2 2 | |
SKIN | + + + + M M + + A + + + + + + + + + + + + + + + + | |
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MUSCULOSKELETAL SYSTEM
BONE | + + + + + A + + + + + + + + + + + + + + + + + + + | |
BONE,FEMUR | + + + + + A + + + + + + + + + + + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY | 2 2 4 1 2 2| |
BONE,STERNUM | + + + + + A + + + + + + + + + + + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 2 1 2 3 3 3 2 3 3 2 2 2 1 2 1 2 3| |
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 | |
POLYARTERITIS | | |
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+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 5
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:31.9
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DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 0| 3| 6| 0| 5| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 0| 6| 7| 5| 0| 5| 7| 8| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 8| 3| 2| 2| 0| 4| 2| 4| 0| 4| 5| 5| 5| 5| 6| 6| 5| 5| 5| 6| 6| 6| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| S R R|
| 0| 3| 8| 6| 7| 8| 0| 1| 1| 8| 9| 9| 9| 9| 2| 3| 2| 3| 3| 6| 6| 5| 9| 9| 9| U V I|
CONTRL F2YR 01 1 | 1| 8| 8| 3| 9| 2| 4| 0| 2| 9| 1| 2| 3| 4| 9| 0| 9| 0| 1| 6| 7| 3| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
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NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DEGENERATION | 2 | |
THROMBUS | 3 | |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DEGENERATION | 2 | |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 1 1 1 1 1 1 1 2 1| |
THROMBUS | 3 | |
PERIPHERAL NERVE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + + + | |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DEGENERATION | 3 | |
THROMBUS | 2 | |
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RESPIRATORY SYSTEM
LARYNX | M M M M + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + + + | |
FOREIGN BODY | X | |
HEMORRHAGE | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 2 2 2 1 1 1 1 1 1 1 2| |
INFLAMMATION | 4 4 1 | |
THROMBUS | 4 | |
NOSE | + + + + + A + + + + + + + + + + + + + + + + + + + | |
CYST,NASOLACRIMAL DUCT | | |
INFLAMMATION | 3 | |
TRACHEA | + + + + + + + + M + + + + + + + + + + + + + + + + | |
INFLAMMATION | 4 | |
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SPECIAL SENSES SYSTEM
EYE | + + + A + A A A A A + + + + + + + + + + + A + + + | |
DEGENERATION,RETINA | | |
THROMBUS | 3 | |
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
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+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 6
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:32.0
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DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 0| 3| 6| 0| 5| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 0| 6| 7| 5| 0| 5| 7| 8| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 8| 3| 2| 2| 0| 4| 2| 4| 0| 4| 5| 5| 5| 5| 6| 6| 5| 5| 5| 6| 6| 6| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| S R R|
| 0| 3| 8| 6| 7| 8| 0| 1| 1| 8| 9| 9| 9| 9| 2| 3| 2| 3| 3| 6| 6| 5| 9| 9| 9| U V I|
CONTRL F2YR 01 1 | 1| 8| 8| 3| 9| 2| 4| 0| 2| 9| 1| 2| 3| 4| 9| 0| 9| 0| 1| 6| 7| 3| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
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SPECIAL SENSES SYSTEM
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1| |
THROMBUS | 2 | |
LACRIMAL GLAND | + + + M + + M M + M + + + + + + + + + M + + + + + | |
ATROPHY | 4 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 1 1 1 3 1 2 1 1 1 | |
ZYMBAL'S GLAND | + + M + + M + + + + M + + + + + + + + + + + + + + | |
INFLAMMATION | 2 | |
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URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AMYLOID DEPOSITION,GLOMERULUS | 3 | |
CONGESTION | 1 | |
CYST,RENAL TUBULE | 1 2 1 1 1| |
HYDRONEPHROSIS,BILATERAL | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 2 1 2 1 1 1 1 1 2 1 2 1 1 1| |
INFLAMMATION | | |
NEPHROPATHY | 1 1 1| |
POLYARTERITIS | | |
URINARY BLADDER | + + A + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 1 2 2 1 1 1| |
POLYARTERITIS | | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 7
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:44.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 7| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| S R R|
| 9| 9| 3| 3| 3| 3| 3| 3| 1| 1| 1| 1| 2| 2| 2| 2| 8| 8| 8| 8| 8| 8| 8| U V I|
CONTRL F2YR 01 1 | 3| 4| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 0| 1| 2| 3| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HYPERKERATOSIS | | 1 2.0|
ULCER | | 1 3.0|
GALLBLADDER | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 | 4 1.0|
INTESTINE LARGE | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
INTESTINE LARGE,CECUM | + + + + + + + + + + + + + + + + + + + + + + + | 42 |
HYPERPLASIA,LYMPHOID | 2 2 2 2 2 | 5 2.0|
INTESTINE LARGE,COLON | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
INTESTINE LARGE,RECTUM | + + + + + + + + + + + + + + + + + M + + + + + | 44 |
EROSION | 2 2 | 2 2.0|
INTESTINE SMALL | + + + + + + + + + + + + + + + + + + + + + + + | 41 |
INTESTINE SMALL,DUODENUM | + + + + + + + + + + + + + + + + + + + + + + + | 40 |
INTESTINE SMALL,ILEUM | + + + + + + + + + + + + + + + + + + + + + + + | 40 |
HYPERPLASIA,LYMPHOID | 2 | 2 2.0|
INTESTINE SMALL,JEJUNUM | + + + + + + + + + + + + + + + + + + + + + + + | 41 |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BASOPHILIC FOCUS | X | 1 |
HEMATOPOIETIC CELL PROLIFERATION | 1 1 | 3 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 1 1 1 1 1 1 1 1 1 1 2 2 1 3 | 33 1.2|
INFLAMMATION | 1 | 2 1.0|
NECROSIS | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 | 32 1.0|
NECROSIS,COAGULATIVE | | 1 2.0|
TENSION LIPOIDOSIS | X X X X X X X X X X X | 17 |
VACUOLIZATION CYTOPLASMIC | 1 1 1 1 1 1 2 2 1 1 1 2 2 1 1 1 1 1 | 26 1.1|
MESENTERY | | 1 |
PANCREAS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY | 2 | 1 2.0|
FOCAL CELLULAR CHANGE | 1 | 2 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 1 1 | 26 1.0|
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HYPERPLASIA,DUCT | | 1 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 2 2 1 2 2 2 1 2 1 1 1 1 1 1 1 2 1 | 38 1.3|
STOMACH | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
STOMACH,FORESTOMACH | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
STOMACH,GLANDULAR | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 8
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:45.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 7| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| S R R|
| 9| 9| 3| 3| 3| 3| 3| 3| 1| 1| 1| 1| 2| 2| 2| 2| 8| 8| 8| 8| 8| 8| 8| U V I|
CONTRL F2YR 01 1 | 3| 4| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 0| 1| 2| 3| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
CRYSTALS | 2 | 1 2.0|
CYST | 1 1 | 2 1.0|
DEGENERATION,HYALINE | 2 | 1 2.0|
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,MAST CELL | 2 | 2 2.0|
POLYARTERITIS | 4 | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + + + + + + + + + + + + + + + + | 42 |
BLOOD VESSEL,AORTA | + + + + + + + + + + + + + + + + + + + + + + + | 42 |
HEART | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
DEGENERATION | | 1 1.0|
INFLAMMATION | | 1 4.0|
POLYARTERITIS | 4 | 1 4.0|
THROMBUS | | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
ACCESSORY ADRENAL CORTICAL NODULE | X | 1 |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
ECTOPIC TISSUE | | 1 |
HYPERPLASIA,SPINDLE CELL | 2 2 2 2 2 2 2 2 2 2 2 1 3 2 3 2 2 3 2 2 1 2 2 | 43 2.0|
THROMBUS | | 1 2.0|
VACUOLIZATION CYTOPLASMIC | 2 2 | 2 2.0|
ADRENAL GLAND,MEDULLA | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
VACUOLIZATION CYTOPLASMIC | | 1 2.0|
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
PARATHYROID GLAND | + M + + + + + + M + M + + + + + + + + + M + + | 38 |
ECTOPIC THYMUS | X | 1 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 3.0|
VACUOLIZATION CYTOPLASMIC | 2 | 1 2.0|
PITUITARY GLAND | + + + + + + + + + + + + + + + M + + + + + + + | 45 |
HYPERPLASIA,PARS DISTALIS | 1 | 4 1.5|
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 9
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:45.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 7| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| S R R|
| 9| 9| 3| 3| 3| 3| 3| 3| 1| 1| 1| 1| 2| 2| 2| 2| 8| 8| 8| 8| 8| 8| 8| U V I|
CONTRL F2YR 01 1 | 3| 4| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 0| 1| 2| 3| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
DEGENERATION | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 | 4 1.2|
ULTIMOBRANCHIAL CYST | 2 2 2 2 2 | 11 2.1|
------------------------------------------------------------------------------------------------------------------------------------
GENERAL BODY SYSTEM
TISSUE NOS | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + + + + + + + + M + + + + + + + + + + + + + | 43 |
ATROPHY | 4 3 4 3 3 3 4 4 3 4 3 3 4 3 4 4 3 3 3 3 2 3 | 40 3.3|
OVARY | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY | X X X X X X X X X X X X X X X X X X X X X | 39 |
CONGESTION | | 1 2.0|
CYST | X X X X X | 10 |
CYST,PERIOVARIAN TISSUE | X X X X X X X X X X | 16 |
HEMATOCYST | X X X X X | 7 |
HYPERPLASIA,ADENOMATOUS | | 2 4.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 1 2 2 | 5 2.0|
UTERUS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ANGIECTASIS | 2 | 1 2.0|
ATROPHY | | 2 3.5|
DILATATION | 4 | 2 3.5|
FIBROSIS | 2 | 1 2.0|
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 3 3 2 3 2 2 2 1 2 2 3 2 3 3 2 2 1 2 | 37 2.2|
PROLAPSE | X | 1 |
VAGINA | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY | | 2 3.5|
DYSPLASIA | 2 | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 | 3 1.3|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HYPERPLASIA | 2 | 3 2.6|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 10
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:45.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 7| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| S R R|
| 9| 9| 3| 3| 3| 3| 3| 3| 1| 1| 1| 1| 2| 2| 2| 2| 8| 8| 8| 8| 8| 8| 8| U V I|
CONTRL F2YR 01 1 | 3| 4| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 0| 1| 2| 3| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HEMORRHAGE | 2 2 2 | 3 2.0|
HYPERPLASIA,LYMPHOID | 3 3 2 | 7 2.2|
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
ATROPHY | 2 | 2 2.0|
HEMORRHAGE | 3 1 2 1 | 4 1.7|
HYPERPLASIA,LYMPHOID | | 2 2.0|
SPLEEN | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ATROPHY | | 2 3.0|
HEMATOPOIETIC CELL PROLIFERATION | 2 | 4 2.7|
HYPERPLASIA,LYMPHOID | 1 1 3 1 3 2 3 4 | 13 2.1|
THYMUS | + + + + + + + M + M + M + + + + + + + + + + + | 41 |
ATROPHY,CORTEX | 3 4 4 3 3 2 3 2 3 2 2 2 2 | 30 3.0|
CONGESTION | | 1 2.0|
ECTOPIC PARATHYROID GLAND | | 1 |
HYPERPLASIA,LYMPHOID,MEDULLA | 3 2 4 2 2 3 1 | 14 2.2|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 44 |
HYPERPLASIA | | 1 2.0|
INFLAMMATION | 1 | 1 1.0|
LACTATION | 2 2 | 4 2.0|
SKIN | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
FIBROUS OSTEODYSTROPHY | 2 2 2 1 2 1 2 1 2 2 2 1 | 18 1.8|
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 2 3 2 3 1 3 3 2 2 1 1 1 4 3 2 3 4 1 1 | 36 2.1|
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 2 1.5|
POLYARTERITIS | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 11
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:45.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 7| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| S R R|
| 9| 9| 3| 3| 3| 3| 3| 3| 1| 1| 1| 1| 2| 2| 2| 2| 8| 8| 8| 8| 8| 8| 8| U V I|
CONTRL F2YR 01 1 | 3| 4| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 0| 1| 2| 3| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
DEGENERATION | | 1 2.0|
THROMBUS | | 1 3.0|
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
DEGENERATION | | 1 2.0|
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 2 1 1 1 1 2 1 2 1 1 1 1 1 1 1 | 28 1.1|
THROMBUS | | 1 3.0|
PERIPHERAL NERVE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
DEGENERATION | | 1 3.0|
THROMBUS | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + + + + + + + + + + + + + + + + + + + + | 44 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
LUNG | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
FOREIGN BODY | | 1 |
HEMORRHAGE | 2 2 | 2 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 2 1 1 1 2 2 3 1 2 2 1 1 1 2 1 1 1 1 1 | 37 1.3|
INFLAMMATION | 1 | 4 2.5|
THROMBUS | | 1 4.0|
NOSE | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
CYST,NASOLACRIMAL DUCT | 2 | 1 2.0|
INFLAMMATION | | 1 3.0|
TRACHEA | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
INFLAMMATION | | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + + + + + + + + + + + + + + + + | 41 |
DEGENERATION,RETINA | 4 | 1 4.0|
THROMBUS | | 1 3.0|
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 12
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:45.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 7| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| S R R|
| 9| 9| 3| 3| 3| 3| 3| 3| 1| 1| 1| 1| 2| 2| 2| 2| 8| 8| 8| 8| 8| 8| 8| U V I|
CONTRL F2YR 01 1 | 3| 4| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 0| 1| 2| 3| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 2 1 | 18 1.0|
THROMBUS | | 1 2.0|
LACRIMAL GLAND | + + + + + + + + + + + + + + + + + + + + M + M | 41 |
ATROPHY | | 1 4.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 2 2 1 1 1 1 1 1 | 25 1.2|
ZYMBAL'S GLAND | + + + + + + + + + + + + M + + + M + + + + + + | 43 |
INFLAMMATION | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AMYLOID DEPOSITION,GLOMERULUS | 2 | 2 2.5|
CONGESTION | | 1 1.0|
CYST,RENAL TUBULE | 1 1 2 1 1 1 1 1 1 | 14 1.1|
HYDRONEPHROSIS,BILATERAL | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 2 2 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 | 39 1.2|
INFLAMMATION | 1 | 1 1.0|
NEPHROPATHY | | 3 1.0|
POLYARTERITIS | 2 | 1 2.0|
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 2 2 1 1 1 1 1 1 2 1 1 1 1 | 38 1.1|
POLYARTERITIS | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 13
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:51.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 0| 6| 6| 6| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 2| 2| 9| 6| 3| 9| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 4| 1| 8| 8| 3| 7| 9| 6| 6| 6| 6| 6| 6| 6| 1| 5| 5| 5| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| S R R|
| 0| 7| 7| 9| 7| 9| 1| 5| 5| 5| 6| 6| 6| 2| 2| 2| 2| 2| 6| 6| 6| 8| 8| 8| 8| U V I|
25MG F2YR 02 2 | 2| 4| 6| 7| 8| 0| 7| 7| 8| 9| 0| 1| 2| 4| 5| 6| 7| 8| 3| 4| 5| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + M + + | |
GALLBLADDER | + + + + + + M + + | |
INTESTINE LARGE | + A + + + + + + + | |
INTESTINE LARGE,CECUM | + A + A + + A + + | |
INTESTINE LARGE,COLON | + A + + + + + + + | |
INTESTINE LARGE,RECTUM | + A + M + + + + + | |
INTESTINE SMALL | + A + A + + A + + | |
INTESTINE SMALL,DUODENUM | + A + A + + A + + | |
INTESTINE SMALL,ILEUM | + A + A + + A + + | |
INTESTINE SMALL,JEJUNUM | + A + A + + A + + | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | 1 | |
BASOPHILIC FOCUS | X | |
CLEAR CELL FOCUS | X | |
EOSINOPHILIC FOCUS | | |
HEMATOPOIETIC CELL PROLIFERATION | 1 1 1 1 1 1 1 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 1 1 2 1 3 1 2 1 2 1 1 2 1 1 | |
NECROSIS | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1| |
TENSION LIPOIDOSIS | X X X X X X X | |
VACUOLIZATION CYTOPLASMIC | 2 2 3 3 2 3 1 2 1 1 1 1 2 2 2 1 1| |
MESENTERY | | |
NECROSIS,FAT | | |
PANCREAS | M + + A + + + + + | |
ATROPHY | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 | |
SALIVARY GLANDS | + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 | |
STOMACH | + + + + + + + + + | |
STOMACH,FORESTOMACH | + + + + + + + + + | |
HYPERKERATOSIS | 2 2 2 | |
ULCER | 2 | |
STOMACH,GLANDULAR | + + + + + + + + + | |
MINERALIZATION | 2 | |
TONGUE | + + + + + + + A + | |
INFLAMMATION | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 14
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:51.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 0| 6| 6| 6| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 2| 2| 9| 6| 3| 9| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 4| 1| 8| 8| 3| 7| 9| 6| 6| 6| 6| 6| 6| 6| 1| 5| 5| 5| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| S R R|
| 0| 7| 7| 9| 7| 9| 1| 5| 5| 5| 6| 6| 6| 2| 2| 2| 2| 2| 6| 6| 6| 8| 8| 8| 8| U V I|
25MG F2YR 02 2 | 2| 4| 6| 7| 8| 0| 7| 7| 8| 9| 0| 1| 2| 4| 5| 6| 7| 8| 3| 4| 5| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + M + + + + + | |
BLOOD VESSEL,AORTA | + + + M + + + + + | |
MINERALIZATION | 4 | |
HEART | + + + + + + + + + | |
DEGENERATION | | |
DILATATION | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + M + + + + + + + | |
ADRENAL GLAND,CORTEX | + M + + + + + + + | |
HYPERPLASIA,SPINDLE CELL | 2 2 1 2 2 2 | |
ADRENAL GLAND,MEDULLA | + M + + + + + + + | |
ISLETS, PANCREATIC | M + + A + + + + + | |
PARATHYROID GLAND | M + + + + + + + + | |
PITUITARY GLAND | M M + + M + + + + M + + + + + + + + + + + + + + + | |
ANGIECTASIS | | |
DEGENERATION,CYSTIC,PARS DISTALIS | | |
HYPERPLASIA,PARS DISTALIS | 1 1 1 | |
THYROID GLAND | M + + + + + + + + | |
CYST,FOLLICLE | 2 | |
DEGENERATION | | |
HYPERPLASIA,FOLLICULAR CELL | 4 | |
ULTIMOBRANCHIAL CYST | 3 3 | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | M M + + + + + + + | |
ATROPHY | 3 4 4 3 3 | |
OVARY | + + + + + + + + + + + + + + + + + + | |
ATROPHY | X X X X X X | |
CYST | X X X X X X X | |
CYST,PERIOVARIAN TISSUE | X X X X | |
HEMATOCYST | X X | |
MINERALIZATION | 4 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 15
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:51.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 0| 6| 6| 6| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 2| 2| 9| 6| 3| 9| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 4| 1| 8| 8| 3| 7| 9| 6| 6| 6| 6| 6| 6| 6| 1| 5| 5| 5| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| S R R|
| 0| 7| 7| 9| 7| 9| 1| 5| 5| 5| 6| 6| 6| 2| 2| 2| 2| 2| 6| 6| 6| 8| 8| 8| 8| U V I|
25MG F2YR 02 2 | 2| 4| 6| 7| 8| 0| 7| 7| 8| 9| 0| 1| 2| 4| 5| 6| 7| 8| 3| 4| 5| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
UTERUS | + + + + + + + + + + + + + + | |
ATROPHY | 3 4 4 4 2 | |
DILATATION | | |
FIBROSIS | 2 | |
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 3 3 3 2 2 | |
INFLAMMATION | 4 | |
VAGINA | + + + + + M + + + | |
ATROPHY | 4 4 2 | |
DYSPLASIA | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + | |
HYPERPLASIA | 4 3 3 2 | |
LYMPH NODE | + + + + + + + + + | |
LYMPH NODE,MANDIBULAR | + + + + + + + + + | |
HEMORRHAGE | 2 2 2 | |
HYPERPLASIA,LYMPHOID | 2 | |
INFILTRATION CELLULAR,HISTIOCYTIC | 3 | |
LYMPH NODE,MESENTERIC | + + + + M + A + + | |
ATROPHY | 4 3 | |
HYPERPLASIA,LYMPHOID | 2 | |
SPLEEN | + + + + + + + + + + + | |
ATROPHY | 3 2 | |
CONGESTION | 1 | |
HEMATOPOIETIC CELL PROLIFERATION | 4 4 4 | |
HYPERPLASIA,LYMPHOID | 1 2 2 1 | |
THYMUS | + M M + + + M M + | |
ATROPHY,CORTEX | 3 4 4 | |
HYPERPLASIA,LYMPHOID,MEDULLA | 2 | |
INFLAMMATION | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M M + M + + + + + | |
HYPERPLASIA | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 16
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:51.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 0| 6| 6| 6| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 2| 2| 9| 6| 3| 9| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 4| 1| 8| 8| 3| 7| 9| 6| 6| 6| 6| 6| 6| 6| 1| 5| 5| 5| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| S R R|
| 0| 7| 7| 9| 7| 9| 1| 5| 5| 5| 6| 6| 6| 2| 2| 2| 2| 2| 6| 6| 6| 8| 8| 8| 8| U V I|
25MG F2YR 02 2 | 2| 4| 6| 7| 8| 0| 7| 7| 8| 9| 0| 1| 2| 4| 5| 6| 7| 8| 3| 4| 5| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM
LACTATION | 2 | |
SKIN | + + + + + + + + + | |
EDEMA | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + | |
BONE,FEMUR | + + + + + + + + + | |
BONE,STERNUM | + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 2 1 1 | |
SKELETAL MUSCLE | + + + + + + + A + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + + + | |
BRAIN,CEREBRUM | + + + + + + + + + | |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 1 | |
PERIPHERAL NERVE | + + + + + + + A + | |
SPINAL CORD | + + + + + + + + + | |
SPINAL CORD,THORACIC | + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + M M + + M M + + | |
INFLAMMATION | 1 | |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,ALVEOLUS | 1| |
INFILTRATION CELLULAR,HISTIOCYTIC | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 1 2 1 1 1 1 1 2 1 1 | |
LEUKOCYTOSIS | 3 | |
MINERALIZATION | 2 | |
THROMBUS | 2 | |
NOSE | + + + + + + + + + | |
MINERALIZATION,NASOLACRIMAL DUCT | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 17
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:51.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 0| 6| 6| 6| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 2| 2| 9| 6| 3| 9| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 4| 1| 8| 8| 3| 7| 9| 6| 6| 6| 6| 6| 6| 6| 1| 5| 5| 5| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| S R R|
| 0| 7| 7| 9| 7| 9| 1| 5| 5| 5| 6| 6| 6| 2| 2| 2| 2| 2| 6| 6| 6| 8| 8| 8| 8| U V I|
25MG F2YR 02 2 | 2| 4| 6| 7| 8| 0| 7| 7| 8| 9| 0| 1| 2| 4| 5| 6| 7| 8| 3| 4| 5| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM
TRACHEA | + + + + + + + + + | |
INFLAMMATION | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | A A + A + + A A + | |
HARDERIAN GLAND | + + + + + + + A + | |
LACRIMAL GLAND | + + + + + M M M + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 | |
ZYMBAL'S GLAND | + M + M + M M + + | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + A + + | |
ACCUMULATION HYALINE DROPLET | 2 2 | |
CYST,RENAL TUBULE | 2 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 | |
MINERALIZATION | 3 | |
NEPHROPATHY | 1 | |
URINARY BLADDER | + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 18
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:53.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| S R R|
| 8| 8| 8| 7| 7| 7| 7| 7| 7| 2| 2| 3| 3| 3| 3| 3| 0| 0| 0| 0| 0| 0| 0| U V I|
25MG F2YR 02 2 | 7| 8| 9| 1| 2| 3| 4| 5| 6| 8| 9| 0| 1| 2| 3| 4| 2| 3| 4| 5| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + | 9 |
GALLBLADDER | M | 8 |
INTESTINE LARGE | + | 9 |
INTESTINE LARGE,CECUM | A | 6 |
INTESTINE LARGE,COLON | + | 9 |
INTESTINE LARGE,RECTUM | + | 8 |
INTESTINE SMALL | + | 7 |
INTESTINE SMALL,DUODENUM | + | 7 |
INTESTINE SMALL,ILEUM | A | 6 |
INTESTINE SMALL,JEJUNUM | A | 6 |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ANGIECTASIS | 1 | 2 1.0|
BASOPHILIC FOCUS | X | 2 |
CLEAR CELL FOCUS | | 1 |
EOSINOPHILIC FOCUS | X | 1 |
HEMATOPOIETIC CELL PROLIFERATION | 1 1 1 1 | 13 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 | 35 1.2|
NECROSIS | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 | 35 1.0|
TENSION LIPOIDOSIS | X X X X X X | 13 |
VACUOLIZATION CYTOPLASMIC | 1 1 1 1 2 2 1 1 2 2 2 1 2 2 2 2 2 2 2 | 36 1.6|
MESENTERY | + | 1 |
NECROSIS,FAT | 3 | 1 3.0|
PANCREAS | + | 8 |
ATROPHY | | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 3 1.0|
SALIVARY GLANDS | + M | 10 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 6 1.0|
STOMACH | + | 10 |
STOMACH,FORESTOMACH | + | 10 |
HYPERKERATOSIS | | 3 2.0|
ULCER | | 1 2.0|
STOMACH,GLANDULAR | + | 10 |
MINERALIZATION | | 1 2.0|
TONGUE | + | 9 |
INFLAMMATION | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 19
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:53.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| S R R|
| 8| 8| 8| 7| 7| 7| 7| 7| 7| 2| 2| 3| 3| 3| 3| 3| 0| 0| 0| 0| 0| 0| 0| U V I|
25MG F2YR 02 2 | 7| 8| 9| 1| 2| 3| 4| 5| 6| 8| 9| 0| 1| 2| 3| 4| 2| 3| 4| 5| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | M | 8 |
BLOOD VESSEL,AORTA | M | 8 |
MINERALIZATION | | 1 4.0|
HEART | + | 10 |
DEGENERATION | 2 | 1 2.0|
DILATATION | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + | 9 |
ADRENAL GLAND,CORTEX | + | 9 |
HYPERPLASIA,SPINDLE CELL | | 6 1.8|
ADRENAL GLAND,MEDULLA | + | 9 |
ISLETS, PANCREATIC | + | 8 |
PARATHYROID GLAND | + | 9 |
PITUITARY GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 44 |
ANGIECTASIS | 1 | 1 1.0|
DEGENERATION,CYSTIC,PARS DISTALIS | 1 1 | 2 1.0|
HYPERPLASIA,PARS DISTALIS | 1 1 1 | 6 1.0|
THYROID GLAND | + | 9 |
CYST,FOLLICLE | | 1 2.0|
DEGENERATION | 2 | 1 2.0|
HYPERPLASIA,FOLLICULAR CELL | | 1 4.0|
ULTIMOBRANCHIAL CYST | | 2 3.0|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + | 8 |
ATROPHY | 4 | 6 3.5|
OVARY | + + + + + + + + + + + | 29 |
ATROPHY | X | 7 |
CYST | X X X X X X X X | 15 |
CYST,PERIOVARIAN TISSUE | X | 5 |
HEMATOCYST | X | 3 |
MINERALIZATION | | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 20
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:53.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| S R R|
| 8| 8| 8| 7| 7| 7| 7| 7| 7| 2| 2| 3| 3| 3| 3| 3| 0| 0| 0| 0| 0| 0| 0| U V I|
25MG F2YR 02 2 | 7| 8| 9| 1| 2| 3| 4| 5| 6| 8| 9| 0| 1| 2| 3| 4| 2| 3| 4| 5| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
UTERUS | + + + + + + + + A + + + + | 26 |
ATROPHY | | 5 3.4|
DILATATION | 4 2 | 2 3.0|
FIBROSIS | | 1 2.0|
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 4 4 4 3 2 2 3 2 2 | 16 2.6|
INFLAMMATION | | 1 4.0|
VAGINA | + | 9 |
ATROPHY | 3 | 4 3.2|
DYSPLASIA | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + | 10 |
HYPERPLASIA | 4 | 5 3.2|
LYMPH NODE | + + + + | 13 |
LYMPH NODE,MANDIBULAR | + + | 11 |
HEMORRHAGE | | 3 2.0|
HYPERPLASIA,LYMPHOID | | 1 2.0|
INFILTRATION CELLULAR,HISTIOCYTIC | | 1 3.0|
LYMPH NODE,MESENTERIC | + + | 9 |
ATROPHY | | 2 3.5|
HYPERPLASIA,LYMPHOID | | 1 2.0|
SPLEEN | + + + | 14 |
ATROPHY | | 2 2.5|
CONGESTION | | 1 1.0|
HEMATOPOIETIC CELL PROLIFERATION | | 3 4.0|
HYPERPLASIA,LYMPHOID | | 4 1.5|
THYMUS | M | 5 |
ATROPHY,CORTEX | | 3 3.6|
HYPERPLASIA,LYMPHOID,MEDULLA | | 1 2.0|
INFLAMMATION | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M | 6 |
HYPERPLASIA | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 21
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:53.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| S R R|
| 8| 8| 8| 7| 7| 7| 7| 7| 7| 2| 2| 3| 3| 3| 3| 3| 0| 0| 0| 0| 0| 0| 0| U V I|
25MG F2YR 02 2 | 7| 8| 9| 1| 2| 3| 4| 5| 6| 8| 9| 0| 1| 2| 3| 4| 2| 3| 4| 5| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM
LACTATION | | 1 2.0|
SKIN | + | 10 |
EDEMA | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + | 10 |
BONE,FEMUR | + | 10 |
BONE,STERNUM | + | 10 |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | | 3 1.3|
SKELETAL MUSCLE | + + | 11 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + | 10 |
BRAIN,CEREBELLUM | + | 10 |
BRAIN,CEREBRUM | + | 10 |
MINERALIZATION,MULTIFOCAL,THALAMUS | | 3 1.0|
PERIPHERAL NERVE | + | 9 |
SPINAL CORD | + | 10 |
SPINAL CORD,THORACIC | + | 10 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | M | 5 |
INFLAMMATION | | 1 1.0|
LUNG | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HYPERPLASIA,ALVEOLUS | | 1 1.0|
INFILTRATION CELLULAR,HISTIOCYTIC | 2 1 | 2 1.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 2 1 1 1 1 | 24 1.1|
LEUKOCYTOSIS | | 1 3.0|
MINERALIZATION | | 1 2.0|
THROMBUS | 1 | 2 1.5|
NOSE | + | 10 |
MINERALIZATION,NASOLACRIMAL DUCT | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 22
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:53.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| S R R|
| 8| 8| 8| 7| 7| 7| 7| 7| 7| 2| 2| 3| 3| 3| 3| 3| 0| 0| 0| 0| 0| 0| 0| U V I|
25MG F2YR 02 2 | 7| 8| 9| 1| 2| 3| 4| 5| 6| 8| 9| 0| 1| 2| 3| 4| 2| 3| 4| 5| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM
TRACHEA | M | 9 |
INFLAMMATION | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | A | 4 |
HARDERIAN GLAND | + + | 10 |
LACRIMAL GLAND | M | 6 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 3 1.0|
ZYMBAL'S GLAND | + | 6 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + | 10 |
ACCUMULATION HYALINE DROPLET | 3 | 3 2.3|
CYST,RENAL TUBULE | | 2 1.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 5 1.0|
MINERALIZATION | | 1 3.0|
NEPHROPATHY | | 1 1.0|
URINARY BLADDER | + | 10 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 6 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 23
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:57.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 9| 2| 4| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 9| 6| 7| 1| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 7| 7| 7| 7| 7| 7| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 2| 2| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| 7| 7| 7| S R R|
| 8| 9| 0| 8| 6| 6| 6| 6| 6| 6| 6| 7| 3| 3| 3| 3| 6| 6| 0| 0| 0| 0| 0| 0| 7| U V I|
50MG F2YR 03 3 | 9| 1| 1| 5| 3| 4| 5| 6| 7| 8| 9| 0| 2| 3| 4| 5| 8| 9| 3| 4| 5| 6| 7| 8| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | M + + + | |
GALLBLADDER | + M + + | |
INTESTINE LARGE | + + A + | |
INTESTINE LARGE,CECUM | + + A + | |
INTESTINE LARGE,COLON | + + A + | |
INTESTINE LARGE,RECTUM | + + A + | |
INTESTINE SMALL | + + A + | |
INTESTINE SMALL,DUODENUM | + + A + | |
INTESTINE SMALL,ILEUM | + + A + | |
INTESTINE SMALL,JEJUNUM | + + A + | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BASOPHILIC FOCUS | X | |
CYST,BILE DUCT | | |
DEGENERATION | 3 | |
EOSINOPHILIC FOCUS | X X X | |
HEMATOPOIETIC CELL PROLIFERATION | 1 1 1 1 1 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 3 3 1 2 2 1 1 2 1 1 2 1 1 1 2| |
NECROSIS | 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1| |
NECROSIS,COAGULATIVE | 3 1 | |
REGENERATION | 3 | |
TENSION LIPOIDOSIS | X X X X X X X X | |
VACUOLIZATION CYTOPLASMIC | 1 3 2 1 2 1 2 2 2 2 1 2| |
MESENTERY | | |
NECROSIS,FAT | | |
PANCREAS | + + + + | |
FOCAL CELLULAR CHANGE | 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
POLYARTERITIS | 4 | |
SALIVARY GLANDS | + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 | |
POLYARTERITIS | 2 | |
STOMACH | + + A + | |
STOMACH,FORESTOMACH | + + A + | |
STOMACH,GLANDULAR | + + A + | |
CYST | 2 | |
TONGUE | + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 24
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:57.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 9| 2| 4| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 9| 6| 7| 1| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 7| 7| 7| 7| 7| 7| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 2| 2| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| 7| 7| 7| S R R|
| 8| 9| 0| 8| 6| 6| 6| 6| 6| 6| 6| 7| 3| 3| 3| 3| 6| 6| 0| 0| 0| 0| 0| 0| 7| U V I|
50MG F2YR 03 3 | 9| 1| 1| 5| 3| 4| 5| 6| 7| 8| 9| 0| 2| 3| 4| 5| 8| 9| 3| 4| 5| 6| 7| 8| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
POLYARTERITIS | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + | |
BLOOD VESSEL,AORTA | + + + + | |
HEART | + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + | |
ADRENAL GLAND,CORTEX | + + + + | |
HYPERPLASIA,SPINDLE CELL | 2 2 | |
ADRENAL GLAND,MEDULLA | M + + + | |
ISLETS, PANCREATIC | + + + + | |
HYPERPLASIA | | |
PARATHYROID GLAND | M M + + | |
PITUITARY GLAND | + + + + + + + + + + + + + + + + + + + + + + + + M | |
ANGIECTASIS | | |
DEGENERATION,CYSTIC,PARS DISTALIS | | |
HYPERPLASIA,PARS DISTALIS | | |
THYROID GLAND | + + + + | |
POLYARTERITIS | 4 | |
ULTIMOBRANCHIAL CYST | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + M M + | |
ATROPHY | 4 3 3 | |
OVARY | M + + + + + + + + + + + | |
ATROPHY | | |
CYST | X X X X X X X | |
CYST,PERIOVARIAN TISSUE | X X | |
HEMATOCYST | X | |
HYPERPLASIA,ADENOMATOUS | 3 | |
UTERUS | + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 25
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:57.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 9| 2| 4| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 9| 6| 7| 1| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 7| 7| 7| 7| 7| 7| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 2| 2| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| 7| 7| 7| S R R|
| 8| 9| 0| 8| 6| 6| 6| 6| 6| 6| 6| 7| 3| 3| 3| 3| 6| 6| 0| 0| 0| 0| 0| 0| 7| U V I|
50MG F2YR 03 3 | 9| 1| 1| 5| 3| 4| 5| 6| 7| 8| 9| 0| 2| 3| 4| 5| 8| 9| 3| 4| 5| 6| 7| 8| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
ANGIECTASIS | 4 | |
ATROPHY | 2 3 | |
DILATATION | 4 | |
FIBROSIS | 2 | |
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 3 2 3 3 2 3 2 2 2 3| |
VAGINA | + + + + | |
ATROPHY | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + | |
LYMPH NODE | + + + + + + | |
HYPERPLASIA,LYMPHOID,INGUINAL | 3 | |
HYPERPLASIA,LYMPHOID,THORACIC | 3 | |
LYMPH NODE,MANDIBULAR | + + M + + | |
HYPERPLASIA,LYMPHOID | 3 | |
LYMPH NODE,MESENTERIC | + + + + + | |
HEMORRHAGE | 2 | |
HYPERPLASIA,LYMPHOID | 3 2 | |
POLYARTERITIS,ARTERY | 4 | |
SPLEEN | + + + + + + + + + + + | |
HEMATOPOIETIC CELL PROLIFERATION | 2 3 3 3 | |
HYPERPLASIA,LYMPHOID | 2 1 | |
THYMUS | + + + + + | |
ATROPHY,CORTEX | 4 4 4 | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M + + + | |
SKIN | + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + | |
BONE,FEMUR | + + + + | |
POLYARTERITIS | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 26
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:57.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 9| 2| 4| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 9| 6| 7| 1| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 7| 7| 7| 7| 7| 7| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 2| 2| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| 7| 7| 7| S R R|
| 8| 9| 0| 8| 6| 6| 6| 6| 6| 6| 6| 7| 3| 3| 3| 3| 6| 6| 0| 0| 0| 0| 0| 0| 7| U V I|
50MG F2YR 03 3 | 9| 1| 1| 5| 3| 4| 5| 6| 7| 8| 9| 0| 2| 3| 4| 5| 8| 9| 3| 4| 5| 6| 7| 8| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
BONE,STERNUM | + + + + | |
SKELETAL MUSCLE | + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + | |
BRAIN,CEREBELLUM | + + + + | |
BRAIN,CEREBRUM | + + + + | |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 | |
POLYARTERITIS | 4 | |
PERIPHERAL NERVE | + + + + | |
SPINAL CORD | + + + + | |
SPINAL CORD,THORACIC | + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | M M M + | |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HEMORRHAGE | 3 | |
INFILTRATION CELLULAR,HISTIOCYTIC | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1| |
THROMBUS | 1 | |
NOSE | + + + + | |
TRACHEA | M + + + | |
ECTASIA,GLANDS | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + | |
HARDERIAN GLAND | + + + + | |
INFLAMMATION | | |
LACRIMAL GLAND | + M + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | |
ZYMBAL'S GLAND | M M + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 27
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:57.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 9| 2| 4| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 9| 6| 7| 1| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 7| 7| 7| 7| 7| 7| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 2| 2| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| 7| 7| 7| S R R|
| 8| 9| 0| 8| 6| 6| 6| 6| 6| 6| 6| 7| 3| 3| 3| 3| 6| 6| 0| 0| 0| 0| 0| 0| 7| U V I|
50MG F2YR 03 3 | 9| 1| 1| 5| 3| 4| 5| 6| 7| 8| 9| 0| 2| 3| 4| 5| 8| 9| 3| 4| 5| 6| 7| 8| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM
KIDNEY | + + + + | |
ACCUMULATION HYALINE DROPLET | 2 | |
CYST,RENAL TUBULE | 2 2 2 | |
GLOMERULOSCLEROSIS | 3 | |
HYDRONEPHROSIS | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 | |
PIGMENTATION,RENAL TUBULE | 3 | |
POLYARTERITIS | 3 | |
URINARY BLADDER | + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 | |
POLYARTERITIS | 4 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 28
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:59.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 0| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9| S R R|
| 7| 7| 8| 8| 8| 8| 8| 1| 4| 4| 4| 4| 4| 4| 4| 0| 1| 1| 1| 1| 1| 1| 1| U V I|
50MG F2YR 03 3 | 8| 9| 0| 1| 2| 3| 4| 0| 0| 1| 2| 3| 4| 5| 6| 9| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + | 4 |
GALLBLADDER | + | 4 |
INTESTINE LARGE | A | 3 |
INTESTINE LARGE,CECUM | A | 3 |
INTESTINE LARGE,COLON | A | 3 |
INTESTINE LARGE,RECTUM | A | 3 |
INTESTINE SMALL | + + + | 6 |
INTESTINE SMALL,DUODENUM | + | 4 |
INTESTINE SMALL,ILEUM | A | 3 |
INTESTINE SMALL,JEJUNUM | + + | 5 |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BASOPHILIC FOCUS | | 1 |
CYST,BILE DUCT | 2 | 1 2.0|
DEGENERATION | | 1 3.0|
EOSINOPHILIC FOCUS | X | 4 |
HEMATOPOIETIC CELL PROLIFERATION | 1 1 1 1 1 1 1 1 1 | 16 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 2 1 2 1 1 1 2 2 1 1 1 1 1 | 40 1.3|
NECROSIS | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 | 31 1.0|
NECROSIS,COAGULATIVE | | 2 2.0|
REGENERATION | | 1 3.0|
TENSION LIPOIDOSIS | X X X X X X X X | 16 |
VACUOLIZATION CYTOPLASMIC | 1 2 2 2 3 2 3 2 2 2 2 2 3 3 2 2 1 2 | 30 1.9|
MESENTERY | + | 1 |
NECROSIS,FAT | 4 | 1 4.0|
PANCREAS | + | 5 |
FOCAL CELLULAR CHANGE | | 2 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 2 1.0|
POLYARTERITIS | | 1 4.0|
SALIVARY GLANDS | + | 5 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 4 1.2|
POLYARTERITIS | | 1 2.0|
STOMACH | + | 4 |
STOMACH,FORESTOMACH | + | 4 |
STOMACH,GLANDULAR | + | 4 |
CYST | | 1 2.0|
TONGUE | + | 5 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 29
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:59.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 0| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9| S R R|
| 7| 7| 8| 8| 8| 8| 8| 1| 4| 4| 4| 4| 4| 4| 4| 0| 1| 1| 1| 1| 1| 1| 1| U V I|
50MG F2YR 03 3 | 8| 9| 0| 1| 2| 3| 4| 0| 0| 1| 2| 3| 4| 5| 6| 9| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
POLYARTERITIS | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + | 5 |
BLOOD VESSEL,AORTA | + | 5 |
HEART | + | 5 |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + | 5 |
ADRENAL GLAND,CORTEX | + | 5 |
HYPERPLASIA,SPINDLE CELL | | 2 2.0|
ADRENAL GLAND,MEDULLA | M | 3 |
ISLETS, PANCREATIC | + | 5 |
HYPERPLASIA | 1 | 1 1.0|
PARATHYROID GLAND | + | 3 |
PITUITARY GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ANGIECTASIS | 1 1 | 2 1.0|
DEGENERATION,CYSTIC,PARS DISTALIS | 2 | 1 2.0|
HYPERPLASIA,PARS DISTALIS | 1 1 1 1 | 4 1.0|
THYROID GLAND | + | 5 |
POLYARTERITIS | | 1 4.0|
ULTIMOBRANCHIAL CYST | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + | 4 |
ATROPHY | 4 | 4 3.5|
OVARY | + + + + + + + + + + | 21 |
ATROPHY | X | 1 |
CYST | X X X X X X | 13 |
CYST,PERIOVARIAN TISSUE | X X | 4 |
HEMATOCYST | X | 2 |
HYPERPLASIA,ADENOMATOUS | | 1 3.0|
UTERUS | + + + + + + + + + + + + + + | 29 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 30
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:59.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 0| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9| S R R|
| 7| 7| 8| 8| 8| 8| 8| 1| 4| 4| 4| 4| 4| 4| 4| 0| 1| 1| 1| 1| 1| 1| 1| U V I|
50MG F2YR 03 3 | 8| 9| 0| 1| 2| 3| 4| 0| 0| 1| 2| 3| 4| 5| 6| 9| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
ANGIECTASIS | | 1 4.0|
ATROPHY | 4 | 3 3.0|
DILATATION | 4 | 2 4.0|
FIBROSIS | | 1 2.0|
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 2 2 4 2 2 3 3 3 2 2 4 | 23 2.5|
VAGINA | + | 5 |
ATROPHY | 3 | 2 3.0|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + | 5 |
LYMPH NODE | + + | 8 |
HYPERPLASIA,LYMPHOID,INGUINAL | | 1 3.0|
HYPERPLASIA,LYMPHOID,THORACIC | | 1 3.0|
LYMPH NODE,MANDIBULAR | + | 5 |
HYPERPLASIA,LYMPHOID | | 1 3.0|
LYMPH NODE,MESENTERIC | + + | 7 |
HEMORRHAGE | | 1 2.0|
HYPERPLASIA,LYMPHOID | | 2 2.5|
POLYARTERITIS,ARTERY | | 1 4.0|
SPLEEN | + + + + + + + + | 19 |
HEMATOPOIETIC CELL PROLIFERATION | 1 | 5 2.4|
HYPERPLASIA,LYMPHOID | 3 2 1 | 5 1.8|
THYMUS | M | 5 |
ATROPHY,CORTEX | | 3 4.0|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + | 5 |
SKIN | + | 5 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + | 5 |
BONE,FEMUR | + | 5 |
POLYARTERITIS | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 31
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:59.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 0| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9| S R R|
| 7| 7| 8| 8| 8| 8| 8| 1| 4| 4| 4| 4| 4| 4| 4| 0| 1| 1| 1| 1| 1| 1| 1| U V I|
50MG F2YR 03 3 | 8| 9| 0| 1| 2| 3| 4| 0| 0| 1| 2| 3| 4| 5| 6| 9| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
BONE,STERNUM | + | 5 |
SKELETAL MUSCLE | + | 5 |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + | 5 |
BRAIN,CEREBELLUM | + | 5 |
BRAIN,CEREBRUM | + | 5 |
MINERALIZATION,MULTIFOCAL,THALAMUS | | 1 1.0|
POLYARTERITIS | | 1 4.0|
PERIPHERAL NERVE | + | 5 |
SPINAL CORD | + | 5 |
SPINAL CORD,THORACIC | + | 5 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | M | 1 |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HEMORRHAGE | | 1 3.0|
INFILTRATION CELLULAR,HISTIOCYTIC | 2 | 2 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 1 1 1 1 1 1 2 1 | 29 1.1|
THROMBUS | | 1 1.0|
NOSE | + | 5 |
TRACHEA | + | 4 |
ECTASIA,GLANDS | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + | 5 |
HARDERIAN GLAND | + + | 6 |
INFLAMMATION | 2 | 1 2.0|
LACRIMAL GLAND | + | 4 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 3 1.3|
ZYMBAL'S GLAND | + | 3 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 32
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:34:59.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 0| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9| S R R|
| 7| 7| 8| 8| 8| 8| 8| 1| 4| 4| 4| 4| 4| 4| 4| 0| 1| 1| 1| 1| 1| 1| 1| U V I|
50MG F2YR 03 3 | 8| 9| 0| 1| 2| 3| 4| 0| 0| 1| 2| 3| 4| 5| 6| 9| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM
KIDNEY | + | 5 |
ACCUMULATION HYALINE DROPLET | | 1 2.0|
CYST,RENAL TUBULE | 1 | 4 1.7|
GLOMERULOSCLEROSIS | | 1 3.0|
HYDRONEPHROSIS | | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 4 1.2|
PIGMENTATION,RENAL TUBULE | | 1 3.0|
POLYARTERITIS | | 1 3.0|
URINARY BLADDER | + | 5 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 5 1.2|
POLYARTERITIS | | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 33
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:14.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 0| 1| 5| 6| 6| 6| 7| 7| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 8| 6| 3| 3| 9| 0| 5| 5| 5| 5| 1| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 9| 6| 9| 8| 1| 2| 6| 6| 6| 4| 1| 0| 1| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 1| 2| 2| 2| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 6| 6| 6| 6| S R R|
| 0| 2| 6| 7| 8| 9| 0| 2| 2| 2| 7| 8| 0| 2| 9| 9| 9| 9| 9| 0| 0| 2| 2| 3| 3| U V I|
100MG F2YR 04 4 | 3| 0| 6| 8| 2| 9| 1| 4| 5| 6| 3| 6| 3| 8| 5| 6| 7| 8| 9| 0| 1| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + M + + + + M + + + + + + M + + + + + + + + + + + | |
HYPERKERATOSIS | 3 | |
GALLBLADDER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 | |
INTESTINE LARGE | + + A + A + A + + + + A + + + + + + + + + + + + + | |
INTESTINE LARGE,CECUM | + + A + A + A + + + + A M A + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | 2 | |
INTESTINE LARGE,COLON | + + A + A + A + + + + A + + + + + + + + + + + + + | |
INTESTINE LARGE,RECTUM | + + A + A + A + + + + A + A + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | | |
INTESTINE SMALL | + + A + A + A + + + + A + A + + + + + + + + + + + | |
INTESTINE SMALL,DUODENUM | + + A + A + A + + + + A + A + + + + + + + + + + + | |
INFLAMMATION | | |
INTESTINE SMALL,ILEUM | A + A + A + A + + + + A + A + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | | |
INFLAMMATION | | |
INTESTINE SMALL,JEJUNUM | A + A + A + A + + + + A + A + + + + + + + + + + + | |
INFLAMMATION | | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BASOPHILIC FOCUS | | |
CONGESTION | 1 | |
EOSINOPHILIC FOCUS | | |
HEMATOPOIETIC CELL PROLIFERATION | 1 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 3 1 1 1 1 1 1 1 1| |
INFLAMMATION | | |
MINERALIZATION | | |
NECROSIS | 1 1 1 2 1 1 1 1 1 1 1| |
TENSION LIPOIDOSIS | X X X X X X | |
VACUOLIZATION CYTOPLASMIC | 2 1 1 1 1 1 1 2 1| |
MESENTERY | | |
NECROSIS,FAT | | |
PANCREAS | + + A + + + + + + + + + + + + + + + + + + + + + + | |
ECTASIA,DUCT | 1 | |
FOCAL CELLULAR CHANGE | 1 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 1 1 1 1 1| |
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 34
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:14.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 0| 1| 5| 6| 6| 6| 7| 7| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 8| 6| 3| 3| 9| 0| 5| 5| 5| 5| 1| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 9| 6| 9| 8| 1| 2| 6| 6| 6| 4| 1| 0| 1| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 1| 2| 2| 2| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 6| 6| 6| 6| S R R|
| 0| 2| 6| 7| 8| 9| 0| 2| 2| 2| 7| 8| 0| 2| 9| 9| 9| 9| 9| 0| 0| 2| 2| 3| 3| U V I|
100MG F2YR 04 4 | 3| 0| 6| 8| 2| 9| 1| 4| 5| 6| 3| 6| 3| 8| 5| 6| 7| 8| 9| 0| 1| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ATROPHY | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 2 2 2 1 2 1 2 1 2 1 2| |
STOMACH | + + A + + + + + + + + A + + + + + + + + + + + + + | |
STOMACH,FORESTOMACH | + + A + + A + + + + + A + + + + + + + + + + + + + | |
HYPERKERATOSIS | 2 2 | |
STOMACH,GLANDULAR | + + A + + + + + + + + A + + + + + + + + + + + + + | |
CYST | 1 | |
MINERALIZATION | | |
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | M M + + + + + + + + + + + + + + + + + + + + + + + | |
BLOOD VESSEL,AORTA | M M + + + + + + + + + + + + + + + + + + + + + + + | |
HEART | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
INFLAMMATION | 2 | |
POLYARTERITIS | | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + M + + + + + + + + + + + | |
ACCESSORY ADRENAL CORTICAL NODULE | | |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + M + + + + + + + + + + + | |
ECTOPIC TISSUE | X | |
HYPERPLASIA | | |
HYPERPLASIA,SPINDLE CELL | 2 3 2 2 2 2 2 1 2 2 3 2 2 2 2 2 1 2 3 1 2| |
ADRENAL GLAND,MEDULLA | + + + + + + + + + + + + + M + + + + + + + + + + + | |
HYPERPLASIA | 1 | |
VACUOLIZATION CYTOPLASMIC | 1 | |
ISLETS, PANCREATIC | + + A + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | 1 | |
PARATHYROID GLAND | + + + + + + + + + + M + + M + + + + + + + + + + M | |
CYST | | |
ECTOPIC THYMUS | X X | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 35
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:14.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 0| 1| 5| 6| 6| 6| 7| 7| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 8| 6| 3| 3| 9| 0| 5| 5| 5| 5| 1| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 9| 6| 9| 8| 1| 2| 6| 6| 6| 4| 1| 0| 1| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 1| 2| 2| 2| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 6| 6| 6| 6| S R R|
| 0| 2| 6| 7| 8| 9| 0| 2| 2| 2| 7| 8| 0| 2| 9| 9| 9| 9| 9| 0| 0| 2| 2| 3| 3| U V I|
100MG F2YR 04 4 | 3| 0| 6| 8| 2| 9| 1| 4| 5| 6| 3| 6| 3| 8| 5| 6| 7| 8| 9| 0| 1| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
VACUOLIZATION CYTOPLASMIC | | |
PITUITARY GLAND | M + + + M + + + + + M + + + + + + + + + + + + + + | |
ANGIECTASIS | | |
HEMORRHAGE | 2 | |
HYPERPLASIA,PARS DISTALIS | 3 2 2| |
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CRYSTALS | | |
DEGENERATION | 2 | |
ECTOPIC THYMUS | | |
HYPERPLASIA,FOLLICULAR CELL | 2 2| |
ULTIMOBRANCHIAL CYST | 2 2 3 | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | M + + + + + + + + + + + + M + + + + + + + + + + + | |
ATROPHY | 3 1 3 2 4 4 3 3 3 3 3 3 3 3 3 3 3 3 3| |
OVARY | + + A + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | X X X X X X X X X X X X X X X X X | |
CYST | X X X X X | |
CYST,PERIOVARIAN TISSUE | X X X X X X X X X | |
HEMATOCYST | X X | |
HYPERPLASIA,ADENOMATOUS | | |
HYPERPLASIA,TUBULAR | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 | |
MINERALIZATION | | |
POLYARTERITIS | | |
UTERUS | + + A + + + + + + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | | |
ATROPHY | 3 3 | |
FIBROSIS | | |
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 3 2 1 2 3 4 2 4 2 3 3 2 2 2 4 3| |
HYPERTROPHY,MYOMETRIUM | 2 | |
METAPLASIA,SQUAMOUS | | |
PROLAPSE | X | |
VAGINA | + + + M + M A + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 2 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 36
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:14.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 0| 1| 5| 6| 6| 6| 7| 7| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 8| 6| 3| 3| 9| 0| 5| 5| 5| 5| 1| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 9| 6| 9| 8| 1| 2| 6| 6| 6| 4| 1| 0| 1| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 1| 2| 2| 2| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 6| 6| 6| 6| S R R|
| 0| 2| 6| 7| 8| 9| 0| 2| 2| 2| 7| 8| 0| 2| 9| 9| 9| 9| 9| 0| 0| 2| 2| 3| 3| U V I|
100MG F2YR 04 4 | 3| 0| 6| 8| 2| 9| 1| 4| 5| 6| 3| 6| 3| 8| 5| 6| 7| 8| 9| 0| 1| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
DYSPLASIA | 2 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + A + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | 4 4 3 3 | |
LYMPH NODE | + + A + + + + + + + + + + + + + + + + + + + + + + | |
HEMATOPOIETIC CELL PROLIFERATION | | |
HEMATOPOIETIC CELL PROLIFERATION,INGUINAL | | |
HEMORRHAGE,INGUINAL | | |
INFILTRATION CELLULAR,HISTIOCYTIC,INGUINAL| | |
LYMPH NODE,MANDIBULAR | + + A + + + + + + + + + + + + + + + + + + + + + + | |
HEMATOPOIETIC CELL PROLIFERATION | | |
HYPERPLASIA,LYMPHOID | 2 | |
HYPERPLASIA,PLASMA CELL | 3 | |
LYMPH NODE,MESENTERIC | A + A + + + + + + + + + + + + + + + + + + + M + + | |
ATROPHY | 4 | |
HEMATOPOIETIC CELL PROLIFERATION | | |
HEMORRHAGE | | |
HYPERPLASIA,LYMPHOID | | |
INFILTRATION CELLULAR,HISTIOCYTIC | | |
SPLEEN | + + M + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | | |
CONGESTION | 3 1 1 | |
HEMATOPOIETIC CELL PROLIFERATION | 3 3 3 3 | |
HYPERPLASIA,LYMPHOID | 2 3 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
INFILTRATION CELLULAR,PLASMA CELL | 2 | |
INFLAMMATION | | |
THYMUS | M M + + + + + + + + + + + M + + + + + + + + + + + | |
ATROPHY,CORTEX | 4 3 2 4 3 2 4 2 3 2 2 3 3 3 4 2 2| |
CYST | | |
ECTOPIC PARATHYROID GLAND | X | |
HYPERPLASIA,LYMPHOID,MEDULLA | 2 2 3 2 2 2 2 2| |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 37
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:15.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 0| 1| 5| 6| 6| 6| 7| 7| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 8| 6| 3| 3| 9| 0| 5| 5| 5| 5| 1| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 9| 6| 9| 8| 1| 2| 6| 6| 6| 4| 1| 0| 1| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 1| 2| 2| 2| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 6| 6| 6| 6| S R R|
| 0| 2| 6| 7| 8| 9| 0| 2| 2| 2| 7| 8| 0| 2| 9| 9| 9| 9| 9| 0| 0| 2| 2| 3| 3| U V I|
100MG F2YR 04 4 | 3| 0| 6| 8| 2| 9| 1| 4| 5| 6| 3| 6| 3| 8| 5| 6| 7| 8| 9| 0| 1| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + A M + + + + + + + + + M + + + + + + + + + + + | |
HYPERPLASIA | 2 3 3 2 | |
LACTATION | | |
SKIN | + + A M + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BONE,FEMUR | M + + + + + + + + + + + + + + + + + + + + + + + + | |
DEGENERATION,CARTILAGE | | |
FIBROUS OSTEODYSTROPHY | 3 2 | |
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 1 4 1 2 3 3 3 3 3 3 2 2 | |
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 1 1 1 1 1 2 2 | |
PERIPHERAL NERVE | + + + + + + + + + M + + + + + + + + + + + + + + M | |
SPINAL CORD | M + + + + + + + + + + + + + + + + + + + + + + + + | |
SPINAL CORD,THORACIC | M + + + + + + + + + + + + + + + + + + + + + + + + | |
DEVELOPMENTAL MALFORMATION | 2| |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + M M M + + + + + M M + + + + + + + + + + + + + | |
INFLAMMATION | | |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,ALVEOLAR EPITHELIUM | | |
INFILTRATION CELLULAR,HISTIOCYTIC | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 38
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:15.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 0| 1| 5| 6| 6| 6| 7| 7| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 8| 6| 3| 3| 9| 0| 5| 5| 5| 5| 1| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 9| 6| 9| 8| 1| 2| 6| 6| 6| 4| 1| 0| 1| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 1| 2| 2| 2| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 6| 6| 6| 6| S R R|
| 0| 2| 6| 7| 8| 9| 0| 2| 2| 2| 7| 8| 0| 2| 9| 9| 9| 9| 9| 0| 0| 2| 2| 3| 3| U V I|
100MG F2YR 04 4 | 3| 0| 6| 8| 2| 9| 1| 4| 5| 6| 3| 6| 3| 8| 5| 6| 7| 8| 9| 0| 1| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 1 1 2 1 1 1 1 1 1 1 2| |
INFLAMMATION | 3 2 | |
NOSE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CYTOPLASMIC ALTERATION,RESPIRATORY EPITHEL| | |
IUM | | |
INFILTRATION CELLULAR,LYMPHOCYTIC,GLANDS | | |
INFILTRATION CELLULAR,LYMPHOCYTIC,NASOLACR| | |
IMAL DUCT | | |
TRACHEA | + M + + + + + + + + + + + M + + + + + + + + + + + | |
ECTASIA,GLANDS | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | A + A + A A A + + + + A + A + + + + + + + + + + + | |
HARDERIAN GLAND | + + + + + + + + + M + + + + + + + + + + + + + + + | |
HYPERPLASIA | 3 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1| |
LACRIMAL GLAND | + + A + + + M M + M + + + M + M + + + + + + M + + | |
ATROPHY | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 2 2 1 1 1| |
ZYMBAL'S GLAND | M + M M + M + + + + M + M + + + + + + + M + + + + | |
INFLAMMATION | | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ACCUMULATION HYALINE DROPLET | 3 1 | |
AMYLOID DEPOSITION,GLOMERULUS | 4 | |
CYST,RENAL TUBULE | 3 1 1 1 1 1 1 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 3 1 1 1 2 1 2 1 2 1 1 1 1 2 1 1 2| |
NECROSIS,RENAL TUBULE | | |
PIGMENTATION,RENAL TUBULE | 2 | |
URINARY BLADDER | A + M M + + A + + + + + + A + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 1 1 1 1 1 1 1 2 1 1 1 1| |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 39
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:29.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| S R R|
| 3| 9| 9| 9| 9| 9| 0| 0| 0| 4| 4| 4| 4| 1| 3| 3| 3| 3| 3| 3| 3| 3| 3| U V I|
100MG F2YR 04 4 | 2| 5| 6| 7| 8| 9| 0| 1| 2| 0| 1| 2| 3| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + M + + + + + + + + + + + + + + + | 44 |
HYPERKERATOSIS | | 1 3.0|
GALLBLADDER | + + M + + + + + + + + + + + + + + + + + + + + | 47 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 4 1.2|
INTESTINE LARGE | + + + + + + + + + + + + + + + + + + + + + + + | 44 |
INTESTINE LARGE,CECUM | + + + + + + + + + + + + + A + + + + + + + + + | 41 |
HYPERPLASIA,LYMPHOID | 2 2 2 | 4 2.0|
INTESTINE LARGE,COLON | + + + + + + + + + + + + + A + + + + + + + + + | 43 |
INTESTINE LARGE,RECTUM | + + + + + + + + + + + + + + + + + + + + + + + | 43 |
HYPERPLASIA,LYMPHOID | 2 | 1 2.0|
INTESTINE SMALL | + + + + + + + + + + + + + A + + + + + + + + + | 42 |
INTESTINE SMALL,DUODENUM | + + + + + + + + + + + + + A + + + + + + + + + | 42 |
INFLAMMATION | 2 | 1 2.0|
INTESTINE SMALL,ILEUM | + M + + + + + + M + + + + A + + + + + + + + + | 39 |
HYPERPLASIA,LYMPHOID | 2 | 1 2.0|
INFLAMMATION | 2 | 1 2.0|
INTESTINE SMALL,JEJUNUM | + + + + + + + + + + + + + A + + + + + + + + + | 41 |
INFLAMMATION | 2 | 1 2.0|
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BASOPHILIC FOCUS | X X | 2 |
CONGESTION | | 1 1.0|
EOSINOPHILIC FOCUS | X | 1 |
HEMATOPOIETIC CELL PROLIFERATION | 1 | 4 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 3 1 3 1 1 1 1 2 1 1 1 | 36 1.1|
INFLAMMATION | 3 | 1 3.0|
MINERALIZATION | 1 | 1 1.0|
NECROSIS | 1 2 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 | 32 1.0|
TENSION LIPOIDOSIS | X X X X X X X X X X | 16 |
VACUOLIZATION CYTOPLASMIC | 1 2 1 1 1 1 1 1 2 2 1 1 1 2 | 23 1.2|
MESENTERY | + | 1 |
NECROSIS,FAT | 4 | 1 4.0|
PANCREAS | + + + + + + + + + + + + + + + M + + + + + + + | 46 |
ECTASIA,DUCT | | 1 1.0|
FOCAL CELLULAR CHANGE | | 2 1.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 2 1 1 1 1 | 19 1.1|
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 40
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:29.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| S R R|
| 3| 9| 9| 9| 9| 9| 0| 0| 0| 4| 4| 4| 4| 1| 3| 3| 3| 3| 3| 3| 3| 3| 3| U V I|
100MG F2YR 04 4 | 2| 5| 6| 7| 8| 9| 0| 1| 2| 0| 1| 2| 3| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ATROPHY | 1 | 2 1.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 1 2 1 2 1 1 1 1 1 1 1 1 2 1 2 1 | 41 1.2|
STOMACH | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
STOMACH,FORESTOMACH | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
HYPERKERATOSIS | | 2 2.0|
STOMACH,GLANDULAR | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
CYST | 1 1 | 3 1.0|
MINERALIZATION | 1 1 | 2 1.0|
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + + + + + + + + + M + + + + + + | 45 |
BLOOD VESSEL,AORTA | + + + + + + + + + + + + + + + + M + + + + + + | 45 |
HEART | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 2 1.0|
INFLAMMATION | | 1 2.0|
POLYARTERITIS | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ACCESSORY ADRENAL CORTICAL NODULE | X | 1 |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ECTOPIC TISSUE | X | 2 |
HYPERPLASIA | 1 | 1 1.0|
HYPERPLASIA,SPINDLE CELL | 2 2 2 2 2 1 2 2 2 1 1 1 2 3 2 3 2 2 2 2 1 3 1 | 44 1.9|
ADRENAL GLAND,MEDULLA | + + + + + + + + + + + + + + M + + + + + + + + | 46 |
HYPERPLASIA | 2 | 2 1.5|
VACUOLIZATION CYTOPLASMIC | | 1 1.0|
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + M + + + + + + + | 46 |
HYPERPLASIA | | 1 1.0|
PARATHYROID GLAND | + + + + + M M + M + + + M + + + + + + + + + M | 40 |
CYST | 2 | 1 2.0|
ECTOPIC THYMUS | | 2 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 41
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:29.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| S R R|
| 3| 9| 9| 9| 9| 9| 0| 0| 0| 4| 4| 4| 4| 1| 3| 3| 3| 3| 3| 3| 3| 3| 3| U V I|
100MG F2YR 04 4 | 2| 5| 6| 7| 8| 9| 0| 1| 2| 0| 1| 2| 3| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
VACUOLIZATION CYTOPLASMIC | 2 | 1 2.0|
PITUITARY GLAND | + M M + M + + + + + + + + + M + + + + + + + + | 41 |
ANGIECTASIS | 2 | 1 2.0|
HEMORRHAGE | | 1 2.0|
HYPERPLASIA,PARS DISTALIS | 3 2 2 2 2 2 | 9 2.2|
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
CRYSTALS | 1 | 1 1.0|
DEGENERATION | | 1 2.0|
ECTOPIC THYMUS | X | 1 |
HYPERPLASIA,FOLLICULAR CELL | | 2 2.0|
ULTIMOBRANCHIAL CYST | 2 2 2 2 2 2 4 | 10 2.3|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + M + + + + + + + + M + + M + + + + + + + + | 43 |
ATROPHY | 3 3 4 3 3 4 4 3 3 2 4 4 3 3 3 3 3 3 3 | 38 3.0|
OVARY | + M + + + + + + + + + + + + + + + + + + + + + | 46 |
ATROPHY | X X X X X X X X X X X X X X X X X X | 35 |
CYST | X X X X X X X X X | 14 |
CYST,PERIOVARIAN TISSUE | X X X X X X | 15 |
HEMATOCYST | X | 3 |
HYPERPLASIA,ADENOMATOUS | 4 | 1 4.0|
HYPERPLASIA,TUBULAR | 1 3 | 2 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 2 2.5|
MINERALIZATION | 1 | 1 1.0|
POLYARTERITIS | 2 | 1 2.0|
UTERUS | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ANGIECTASIS | 3 | 1 3.0|
ATROPHY | | 2 3.0|
FIBROSIS | 2 | 1 2.0|
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 4 3 3 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 | 37 2.4|
HYPERTROPHY,MYOMETRIUM | 3 | 2 2.5|
METAPLASIA,SQUAMOUS | 2 | 1 2.0|
PROLAPSE | | 1 |
VAGINA | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
ATROPHY | 4 | 3 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 42
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:29.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| S R R|
| 3| 9| 9| 9| 9| 9| 0| 0| 0| 4| 4| 4| 4| 1| 3| 3| 3| 3| 3| 3| 3| 3| 3| U V I|
100MG F2YR 04 4 | 2| 5| 6| 7| 8| 9| 0| 1| 2| 0| 1| 2| 3| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
DYSPLASIA | | 2 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 2 1.0|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HYPERPLASIA | 2 4 | 6 3.3|
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HEMATOPOIETIC CELL PROLIFERATION | 4 | 1 4.0|
HEMATOPOIETIC CELL PROLIFERATION,INGUINAL | 4 | 1 4.0|
HEMORRHAGE,INGUINAL | 2 | 1 2.0|
INFILTRATION CELLULAR,HISTIOCYTIC,INGUINAL| 3 | 1 3.0|
LYMPH NODE,MANDIBULAR | + + + + + + + + + M + + + + + + + + + + + + + | 46 |
HEMATOPOIETIC CELL PROLIFERATION | 4 | 1 4.0|
HYPERPLASIA,LYMPHOID | 2 2 2 2 3 2 3 3 | 9 2.3|
HYPERPLASIA,PLASMA CELL | | 1 3.0|
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + + + M + + + + + + + + | 44 |
ATROPHY | | 1 4.0|
HEMATOPOIETIC CELL PROLIFERATION | 3 | 1 3.0|
HEMORRHAGE | 3 4 | 2 3.5|
HYPERPLASIA,LYMPHOID | 2 3 | 2 2.5|
INFILTRATION CELLULAR,HISTIOCYTIC | 4 | 1 4.0|
SPLEEN | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ATROPHY | 2 | 1 2.0|
CONGESTION | | 3 1.6|
HEMATOPOIETIC CELL PROLIFERATION | 3 3 3 4 2 | 9 3.0|
HYPERPLASIA,LYMPHOID | 3 1 1 1 1 1 4 | 11 1.7|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
INFILTRATION CELLULAR,PLASMA CELL | | 1 2.0|
INFLAMMATION | 4 | 1 4.0|
THYMUS | + M + + + + + + + + + + + + + + + + + + + + + | 44 |
ATROPHY,CORTEX | 3 3 4 3 2 2 3 2 3 3 2 3 3 3 4 3 3 | 34 2.8|
CYST | 2 | 1 2.0|
ECTOPIC PARATHYROID GLAND | | 1 |
HYPERPLASIA,LYMPHOID,MEDULLA | 2 2 2 1 2 2 2 3 2 | 17 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 43
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:29.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| S R R|
| 3| 9| 9| 9| 9| 9| 0| 0| 0| 4| 4| 4| 4| 1| 3| 3| 3| 3| 3| 3| 3| 3| 3| U V I|
100MG F2YR 04 4 | 2| 5| 6| 7| 8| 9| 0| 1| 2| 0| 1| 2| 3| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + + + + + + + + + + M + + + + + + + + + | 44 |
HYPERPLASIA | 2 1 1 | 7 2.0|
LACTATION | 2 | 1 2.0|
SKIN | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
DEGENERATION,CARTILAGE | 2 | 1 2.0|
FIBROUS OSTEODYSTROPHY | 2 3 2 1 1 4 2 1 | 10 2.1|
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 2 2 2 1 3 4 1 2 2 2 3 1 2 2 3 3 2 3 4 3 2 | 33 2.3|
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 1 1 1 1 1 1 1 1 1 1 1 | 22 1.0|
PERIPHERAL NERVE | + + M + + + + + + + + + + + + + + + + + + + + | 45 |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
DEVELOPMENTAL MALFORMATION | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + + + + + + + + + + + + + + + + + + + + | 43 |
INFLAMMATION | 2 | 1 2.0|
LUNG | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HYPERPLASIA,ALVEOLAR EPITHELIUM | 4 | 1 4.0|
INFILTRATION CELLULAR,HISTIOCYTIC | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 44
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:29.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| S R R|
| 3| 9| 9| 9| 9| 9| 0| 0| 0| 4| 4| 4| 4| 1| 3| 3| 3| 3| 3| 3| 3| 3| 3| U V I|
100MG F2YR 04 4 | 2| 5| 6| 7| 8| 9| 0| 1| 2| 0| 1| 2| 3| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 1 1 1 2 2 2 1 1 1 2 2 1 | 29 1.3|
INFLAMMATION | | 2 2.5|
NOSE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
CYTOPLASMIC ALTERATION,RESPIRATORY EPITHEL| 1 | 1 1.0|
IUM | | |
INFILTRATION CELLULAR,LYMPHOCYTIC,GLANDS | 1 | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC,NASOLACR| 2 | 1 2.0|
IMAL DUCT | | |
TRACHEA | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
ECTASIA,GLANDS | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + + + + + + A + + + + + + + + + | 40 |
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HYPERPLASIA | | 1 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 | 12 1.0|
LACRIMAL GLAND | + + + + + + + + + + + + + + M + + + + + + + + | 40 |
ATROPHY | 2 2 | 3 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 2 1 1 1 1 1 1 1 | 20 1.2|
ZYMBAL'S GLAND | + + + + + + + + + + + + + + + + + + + + M + + | 40 |
INFLAMMATION | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ACCUMULATION HYALINE DROPLET | | 2 2.0|
AMYLOID DEPOSITION,GLOMERULUS | | 1 4.0|
CYST,RENAL TUBULE | 1 1 1 1 1 1 1 1 | 17 1.1|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 1 2 1 1 1 2 1 1 2 1 1 2 2 2 1 2 | 38 1.3|
NECROSIS,RENAL TUBULE | 1 | 1 1.0|
PIGMENTATION,RENAL TUBULE | | 1 2.0|
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + + + + + | 43 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 | 35 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 45
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:32.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 1| 1| 1| 1| 1| 1| 1| 1|
| 1| 1| 1| 1| 1| 1| 1| 1|
| 9| 9| 9| 9| 9| 9| 9| 9|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 1| 1| 1| 1| 1| 1| 1| 1| U V I|
CONTRL F3MTHR 05 5 | 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + | 8 |
INFLAMMATION,MEDIASTINUM | 4 | 1 4.0|
GALLBLADDER | + + + + + + + + | 8 |
INTESTINE LARGE | + + + + + + + + | 8 |
INTESTINE LARGE,CECUM | + + + + + + + + | 8 |
INTESTINE LARGE,COLON | + + + + + + + + | 8 |
INTESTINE LARGE,RECTUM | + + + + + + + + | 8 |
INTESTINE SMALL | + + + + + + + + | 8 |
INTESTINE SMALL,DUODENUM | + + + + + + + + | 8 |
INTESTINE SMALL,ILEUM | + + + + + + + + | 8 |
INTESTINE SMALL,JEJUNUM | + + + + + + + + | 8 |
LIVER | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
NECROSIS | 1 1 1 1 1 1 | 6 1.0|
PANCREAS | + + + + + + + + | 8 |
SALIVARY GLANDS | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 | 5 1.0|
STOMACH | + + + + + + + + | 8 |
STOMACH,FORESTOMACH | + + + + + + + + | 8 |
STOMACH,GLANDULAR | + + + + + + + + | 8 |
TONGUE | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + M + | 7 |
BLOOD VESSEL,AORTA | + + + + + + M + | 7 |
HEART | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + | 8 |
ADRENAL GLAND,CORTEX | + + + + + + + + | 8 |
HYPERPLASIA,SPINDLE CELL | 1 1 1 1 | 4 1.0|
ADRENAL GLAND,MEDULLA | + + + + + + + + | 8 |
ISLETS, PANCREATIC | + + + + + + + + | 8 |
PARATHYROID GLAND | + + + + + + + M | 7 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 46
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:32.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 1| 1| 1| 1| 1| 1| 1| 1|
| 1| 1| 1| 1| 1| 1| 1| 1|
| 9| 9| 9| 9| 9| 9| 9| 9|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 1| 1| 1| 1| 1| 1| 1| 1| U V I|
CONTRL F3MTHR 05 5 | 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
PITUITARY GLAND | + + + + + + + + | 8 |
THYROID GLAND | + + + + + + + M | 7 |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + M + + + + + + | 7 |
OVARY | + + + + + + + + | 8 |
CONGESTION | 1 | 1 1.0|
UTERUS | + + + + + + + + | 8 |
VAGINA | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + | 8 |
HYPERPLASIA | 2 | 1 2.0|
LYMPH NODE | + + + + + + + + | 8 |
LYMPH NODE,MANDIBULAR | + + + + + + + + | 8 |
HYPERPLASIA,LYMPHOID | 2 | 1 2.0|
LYMPH NODE,MESENTERIC | + M + + + + + + | 7 |
HYPERPLASIA,LYMPHOID | 3 | 1 3.0|
SPLEEN | + + + + + + + + | 8 |
THYMUS | + + + + + + + + | 8 |
CYST | 1 | 1 1.0|
INFLAMMATION,MEDIASTINUM | 1 | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + + + + + | 8 |
SKIN | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + | 8 |
BONE,FEMUR | + + + + + + + + | 8 |
BONE,STERNUM | + + + + + + + + | 8 |
SKELETAL MUSCLE | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 47
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:32.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 1| 1| 1| 1| 1| 1| 1| 1|
| 1| 1| 1| 1| 1| 1| 1| 1|
| 9| 9| 9| 9| 9| 9| 9| 9|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 1| 1| 1| 1| 1| 1| 1| 1| U V I|
CONTRL F3MTHR 05 5 | 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
BRAIN | + + + + + + + + | 8 |
BRAIN,CEREBELLUM | + + + + + + + + | 8 |
BRAIN,CEREBRUM | + + + + + + + + | 8 |
PERIPHERAL NERVE | + + + + + + + + | 8 |
SPINAL CORD | + + + + + + + + | 8 |
SPINAL CORD,THORACIC | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + M M M M M + | 3 |
LUNG | + + + + + + + + | 8 |
CONGESTION | 2 | 1 2.0|
HEMORRHAGE | 1 | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
NOSE | + + + + + + + + | 8 |
TRACHEA | + + + + + + + M | 7 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + | 8 |
HARDERIAN GLAND | + + + + + + + + | 8 |
LACRIMAL GLAND | + + + + + M + + | 7 |
ZYMBAL'S GLAND | + + + + + M + + | 7 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + | 8 |
URINARY BLADDER | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 48
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:34.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 2| 2| 2| 2| 2| 2| 2| 2|
| 1| 1| 1| 1| 1| 1| 1| 1|
| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 2| 2| 2| 2| 2| 2| 2| 2| U V I|
CONTRL F6MTHR 06 6 | 1| 2| 3| 4| 5| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | M + + + + + + + | 7 |
GALLBLADDER | + + + + + + + + | 8 |
INTESTINE LARGE | + + + + + + + + | 8 |
INTESTINE LARGE,CECUM | + + + + + + + + | 8 |
INTESTINE LARGE,COLON | + + + + + + + + | 8 |
INTESTINE LARGE,RECTUM | + + + + + + + + | 8 |
INTESTINE SMALL | + + + + + + + + | 8 |
INTESTINE SMALL,DUODENUM | + + + + + + + + | 8 |
INTESTINE SMALL,ILEUM | + + + + + + + + | 8 |
INTESTINE SMALL,JEJUNUM | + + + + + + + + | 8 |
LIVER | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 | 3 1.0|
NECROSIS | 1 2 1 1 1 | 5 1.2|
TENSION LIPOIDOSIS | X | 1 |
VACUOLIZATION CYTOPLASMIC | 1 1 1 1 1 | 5 1.0|
PANCREAS | + + + + + + + + | 8 |
SALIVARY GLANDS | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 | 4 1.0|
STOMACH | + + + + + + + + | 8 |
STOMACH,FORESTOMACH | + + + + + + + + | 8 |
STOMACH,GLANDULAR | + + + + + + + + | 8 |
INFLAMMATION | 1 | 1 1.0|
TONGUE | + + + + + + + + | 8 |
INFILTRATION CELLULAR,HISTIOCYTIC | 1 | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + M + + + | 7 |
BLOOD VESSEL,AORTA | + + + + M + + + | 7 |
HEART | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + | 8 |
ADRENAL GLAND,CORTEX | + + + + + + + + | 8 |
HYPERPLASIA,SPINDLE CELL | 2 1 1 1 | 4 1.2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 49
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:35.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 2| 2| 2| 2| 2| 2| 2| 2|
| 1| 1| 1| 1| 1| 1| 1| 1|
| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 2| 2| 2| 2| 2| 2| 2| 2| U V I|
CONTRL F6MTHR 06 6 | 1| 2| 3| 4| 5| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
ADRENAL GLAND,MEDULLA | + + + + + + + + | 8 |
ISLETS, PANCREATIC | + + + + + + + + | 8 |
PARATHYROID GLAND | + M M M + M + + | 4 |
ECTOPIC THYMUS | X | 1 |
PITUITARY GLAND | M + M + M + M M | 3 |
THYROID GLAND | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + + + + + + + | 8 |
OVARY | + + + + + + + + | 8 |
CYST | X | 1 |
HEMATOCYST | X | 1 |
UTERUS | + + + + + + + + | 8 |
VAGINA | + + + + M + + + | 7 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + | 8 |
HYPERPLASIA | 3 | 1 3.0|
LYMPH NODE | + + + + + + + + | 8 |
LYMPH NODE,MANDIBULAR | + + + + + + + + | 8 |
FIBROSIS | 3 | 1 3.0|
HYPERPLASIA,LYMPHOID | 2 2 | 2 2.0|
LYMPH NODE,MESENTERIC | + + + + + + + + | 8 |
SPLEEN | + + + + + + + + | 8 |
CONGESTION | 2 | 1 2.0|
HEMATOPOIETIC CELL PROLIFERATION | 3 | 1 3.0|
HYPERPLASIA,LYMPHOID | 2 | 1 2.0|
THYMUS | + + + + M + + + | 7 |
ATROPHY,CORTEX | 2 2 | 2 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 50
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:35.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 2| 2| 2| 2| 2| 2| 2| 2|
| 1| 1| 1| 1| 1| 1| 1| 1|
| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 2| 2| 2| 2| 2| 2| 2| 2| U V I|
CONTRL F6MTHR 06 6 | 1| 2| 3| 4| 5| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + + + + + | 8 |
SKIN | + + + + + + + + | 8 |
HYPERPLASIA | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + | 8 |
BONE,FEMUR | + + + + + + + + | 8 |
BONE,STERNUM | + + + + + + + + | 8 |
SKELETAL MUSCLE | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + | 8 |
BRAIN,CEREBELLUM | + + + + + + + + | 8 |
BRAIN,CEREBRUM | + + + + + + + + | 8 |
PERIPHERAL NERVE | + + + + + + + + | 8 |
SPINAL CORD | + + + + + + + + | 8 |
SPINAL CORD,THORACIC | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + M + M M + M M | 3 |
LUNG | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 | 5 1.0|
NOSE | + + + + + + + + | 8 |
TRACHEA | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + | 8 |
HARDERIAN GLAND | + + + + + + + + | 8 |
LACRIMAL GLAND | + + M + M + + + | 6 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 2 1.0|
ZYMBAL'S GLAND | + + + + + + M + | 7 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 51
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:35.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 2| 2| 2| 2| 2| 2| 2| 2|
| 1| 1| 1| 1| 1| 1| 1| 1|
| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 2| 2| 2| 2| 2| 2| 2| 2| U V I|
CONTRL F6MTHR 06 6 | 1| 2| 3| 4| 5| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM
KIDNEY | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 2 1.0|
URINARY BLADDER | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 2 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 52
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:37.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 3| 3| 3| 3| 3| 3| 3|
| 9| 9| 9| 9| 9| 9| 9| 9|
| 2| 2| 2| 2| 2| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 4| 4| 4| 4| 4| 4| 4| 4| U V I|
CONTRL F12MTHR07 7 | 0| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + | 8 |
HYPERKERATOSIS | 2 | 1 2.0|
GALLBLADDER | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
INTESTINE LARGE | + + + + + + + + | 8 |
INTESTINE LARGE,CECUM | + + + + + + + + | 8 |
INTESTINE LARGE,COLON | + + + + M + + + | 7 |
INTESTINE LARGE,RECTUM | + + + + + + + + | 8 |
CYST | 2 | 1 2.0|
INTESTINE SMALL | + + + + + + + + | 8 |
INTESTINE SMALL,DUODENUM | + + + + + + + + | 8 |
INTESTINE SMALL,ILEUM | + + + + + + + + | 8 |
INTESTINE SMALL,JEJUNUM | + + + + + + + + | 8 |
LIVER | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 | 5 1.0|
TENSION LIPOIDOSIS | X X | 2 |
VACUOLIZATION CYTOPLASMIC | 1 1 1 1 1 | 5 1.0|
MESENTERY | + | 1 |
PANCREAS | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 2 1.0|
SALIVARY GLANDS | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 2 | 7 1.1|
STOMACH | + + + + + + + + | 8 |
STOMACH,FORESTOMACH | + + + + + + + + | 8 |
STOMACH,GLANDULAR | + + + + + + + + | 8 |
TONGUE | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + | 8 |
BLOOD VESSEL,AORTA | + + + + + + + + | 8 |
HEART | + + + + + + + + | 8 |
CARDIOMYOPATHY | 1 | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 53
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:38.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 3| 3| 3| 3| 3| 3| 3|
| 9| 9| 9| 9| 9| 9| 9| 9|
| 2| 2| 2| 2| 2| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 4| 4| 4| 4| 4| 4| 4| 4| U V I|
CONTRL F12MTHR07 7 | 0| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
ADRENAL GLAND | M + + + + + + + | 7 |
ADRENAL GLAND,CORTEX | M + + + + + + + | 7 |
HYPERPLASIA,SPINDLE CELL | 2 3 2 2 2 1 | 6 2.0|
ADRENAL GLAND,MEDULLA | M + + + + + + + | 7 |
ISLETS, PANCREATIC | + + + + + + + + | 8 |
PARATHYROID GLAND | + M M M + + M M | 3 |
PITUITARY GLAND | M M + + + M + + | 5 |
THYROID GLAND | + M + + + + M + | 6 |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | M + + + + M + + | 6 |
ATROPHY | 4 2 2 2 4 | 5 2.8|
OVARY | + + + + + + + + | 8 |
ATROPHY | X X | 2 |
UTERUS | + + + + + + + + | 8 |
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 1 2 | 2 1.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
VAGINA | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 | 3 1.0|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + | 8 |
HYPERPLASIA | 3 | 1 3.0|
LYMPH NODE | + + + + + + + + | 8 |
LYMPH NODE,MANDIBULAR | + + + + + + + + | 8 |
HYPERPLASIA,LYMPHOID | 2 2 2 | 3 2.0|
LYMPH NODE,MESENTERIC | + + + + + + + + | 8 |
SPLEEN | + + + + + + + + | 8 |
HYPERPLASIA,LYMPHOID | 2 | 1 2.0|
THYMUS | + + M + + + + + | 7 |
ATROPHY,CORTEX | 3 2 2 | 3 2.3|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 54
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:38.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 3| 3| 3| 3| 3| 3| 3|
| 9| 9| 9| 9| 9| 9| 9| 9|
| 2| 2| 2| 2| 2| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 4| 4| 4| 4| 4| 4| 4| 4| U V I|
CONTRL F12MTHR07 7 | 0| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + + + + + | 8 |
SKIN | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + | 8 |
BONE,FEMUR | + + + + + + + + | 8 |
BONE,STERNUM | + + + + + + + + | 8 |
SKELETAL MUSCLE | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + | 8 |
BRAIN,CEREBELLUM | + + + + + + + + | 8 |
BRAIN,CEREBRUM | + + + + + + + + | 8 |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 | 1 1.0|
PERIPHERAL NERVE | + + + + + + + + | 8 |
SPINAL CORD | + + + + + + + + | 8 |
SPINAL CORD,THORACIC | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | M + + + + + + M | 6 |
LUNG | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 1 1 1 1 | 7 1.1|
NOSE | + + + + + + + + | 8 |
TRACHEA | + M + + + + M + | 6 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + | 8 |
HARDERIAN GLAND | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
LACRIMAL GLAND | M + + + + + + + | 7 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 2 1 | 3 1.6|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 55
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:38.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 3| 3| 3| 3| 3| 3| 3|
| 9| 9| 9| 9| 9| 9| 9| 9|
| 2| 2| 2| 2| 2| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 4| 4| 4| 4| 4| 4| 4| 4| U V I|
CONTRL F12MTHR07 7 | 0| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
ZYMBAL'S GLAND | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 | 7 1.0|
NEPHROPATHY | 2 | 1 2.0|
URINARY BLADDER | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 | 6 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 56
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:52.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 5| 2| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 4| 6| 5| 9| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 4| 0| 2| 2| 8| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 2| 2| 2| 3| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| S R R|
| 6| 6| 7| 8| 2| 1| 1| 1| 1| 1| 2| 2| 2| 4| 4| 5| 5| 5| 2| 2| 2| 2| 2| 2| 2| U V I|
100MG F3MTH 08 8 | 5| 7| 5| 0| 2| 5| 6| 7| 8| 9| 0| 1| 2| 8| 9| 0| 1| 2| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
GALLBLADDER | + + + + A + + + + + + M + + + + + + + + + + + + M | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
INTESTINE LARGE | + + + A A + + + + + + + A + + + + + + + + + + + + | |
INTESTINE LARGE,CECUM | + + + A A + + + + + + + A + + + + + + + + + + + + | |
INTESTINE LARGE,COLON | + + + A A + + + + + + + A + + + + + + + + + + + + | |
INTESTINE LARGE,RECTUM | + + + A A + + + + + + + A + + + + + + + + + + + + | |
INFLAMMATION | 3 | |
INTESTINE SMALL | + + + A A + + + + + + + A + + + + + + + + + + + + | |
INTESTINE SMALL,DUODENUM | + + + A A + + + + + + + A + + + + + + + + + + + + | |
INTESTINE SMALL,ILEUM | + + + A A + + + + + + + A + + + + + + + + + M + + | |
HYPERPLASIA,LYMPHOID | | |
INTESTINE SMALL,JEJUNUM | + + + A A + + + + + + + A + + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
APOPTOSIS | | |
ATROPHY | 1 | |
EOSINOPHILIC FOCUS | X | |
HEMATOPOIETIC CELL PROLIFERATION | 1 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1| |
INFILTRATION CELLULAR,PLASMA CELL | | |
LEUKOCYTOSIS | 1 | |
NECROSIS | 3 1 1 1 1 1 1 1 1 1 1 1 1 1| |
TENSION LIPOIDOSIS | X X X X X | |
VACUOLIZATION CYTOPLASMIC | 3 2 1 1 1 1 1 1 1 1 1 1 2 1 1 2 1 1| |
MESENTERY | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
PANCREAS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 1 | |
ECTASIA,DUCT | 3 | |
FOCAL CELLULAR CHANGE | 1 3 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1| |
INFLAMMATION | | |
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 2 2 1 1 1 2 1 1 1 1 2 1 1 1| |
INFLAMMATION | | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 57
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:52.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 5| 2| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 4| 6| 5| 9| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 4| 0| 2| 2| 8| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 2| 2| 2| 3| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| S R R|
| 6| 6| 7| 8| 2| 1| 1| 1| 1| 1| 2| 2| 2| 4| 4| 5| 5| 5| 2| 2| 2| 2| 2| 2| 2| U V I|
100MG F3MTH 08 8 | 5| 7| 5| 0| 2| 5| 6| 7| 8| 9| 0| 1| 2| 8| 9| 0| 1| 2| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
MINERALIZATION | | |
STOMACH | + + + A A + + + + + + + A + + + + + + + + + + + + | |
STOMACH,FORESTOMACH | + + + A A + + + + + + + A + + + + + + + + + + + + | |
STOMACH,GLANDULAR | + + + A A + + + + + + + A + + + + + + + + + + + + | |
CYST | | |
TONGUE | + + + A + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,MAST CELL | 2 2 | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + M M + M + + + + M + + + + + + + + + + + + + + + | |
BLOOD VESSEL,AORTA | + M M + M + + + + M + + + + + + + + + + + + + + + | |
HEART | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
INFLAMMATION | 4 | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFLAMMATION,EXTRA ADRENAL TISSUE | | |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,SPINDLE CELL | 2 1 3 1 2 2 2 2 2 1 3 2 1 3 2 2 2 3 2 3 1 1 | |
VACUOLIZATION CYTOPLASMIC | 1 | |
ADRENAL GLAND,MEDULLA | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CONGESTION | | |
VACUOLIZATION CYTOPLASMIC | | |
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
PARATHYROID GLAND | + + + M + + + + + + + M + M M + + + + M M + + M M | |
PITUITARY GLAND | + + + M M + + + + + + + + + + + + + + + + + + + M | |
ANGIECTASIS | 1 | |
CYST | | |
HYPERPLASIA,PARS DISTALIS | 3 | |
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CYST,FOLLICLE | 1 | |
HYPERPLASIA,FOLLICULAR CELL | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 58
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:52.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 5| 2| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 4| 6| 5| 9| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 4| 0| 2| 2| 8| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 2| 2| 2| 3| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| S R R|
| 6| 6| 7| 8| 2| 1| 1| 1| 1| 1| 2| 2| 2| 4| 4| 5| 5| 5| 2| 2| 2| 2| 2| 2| 2| U V I|
100MG F3MTH 08 8 | 5| 7| 5| 0| 2| 5| 6| 7| 8| 9| 0| 1| 2| 8| 9| 0| 1| 2| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
INFLAMMATION | 1 | |
ULTIMOBRANCHIAL CYST | 2 2 2 2 | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + + + + + + + + M + + + + + + + + + + + + + + M | |
ATROPHY | 3 3 3 2 3 4 4 4 4 3 4 3 4 3 4 3 4 3 3 4 3 | |
INFLAMMATION | 2 | |
OVARY | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | X X X X X X X X X X X X X X X X X X X | |
CYST | X X X X | |
CYST,PERIOVARIAN TISSUE | X X X X X X X X | |
HEMATOCYST | X | |
HYPERPLASIA,ADENOMATOUS | 3 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
UTERUS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 3 | |
DILATATION | 4 | |
FIBROSIS | 2 | |
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 1 3 3 2 2 2 2 2 2 2 2 2 3 2 2 3| |
THROMBUS | 2 | |
VAGINA | + + + + M + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 3 | |
DYSPLASIA | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
INFLAMMATION | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + M + + + | |
HYPERPLASIA | 2 4 3 3| |
HYPOPLASIA | 2 | |
PIGMENTATION | 3 | |
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,PLASMA CELL,MEDIASTINAL | | |
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 59
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:52.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 5| 2| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 4| 6| 5| 9| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 4| 0| 2| 2| 8| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 2| 2| 2| 3| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| S R R|
| 6| 6| 7| 8| 2| 1| 1| 1| 1| 1| 2| 2| 2| 4| 4| 5| 5| 5| 2| 2| 2| 2| 2| 2| 2| U V I|
100MG F3MTH 08 8 | 5| 7| 5| 0| 2| 5| 6| 7| 8| 9| 0| 1| 2| 8| 9| 0| 1| 2| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
ATROPHY | 3 | |
HEMATOPOIETIC CELL PROLIFERATION | 2 | |
HEMORRHAGE | 1 | |
HYPERPLASIA,LYMPHOID | 2 2 2 | |
HYPERPLASIA,PLASMA CELL | | |
INFLAMMATION | 2 | |
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 4 | |
FIBROSIS | 2 | |
HEMORRHAGE | 4 | |
HYPERPLASIA,LYMPHOID | 3| |
HYPERPLASIA,PLASMA CELL | | |
SPLEEN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 4 | |
HEMATOPOIETIC CELL PROLIFERATION | 3 4 3 | |
HYPERPLASIA,LYMPHOID | 1 1 2 1 3 3 | |
HYPERPLASIA,PLASMA CELL,RED PULP | | |
THYMUS | + M + M M + M + + + + + + + + + + + M M + + + + + | |
ATROPHY,CORTEX | 4 4 3 4 2 3 3 3 4 3 2 2 2 3 3| |
HYPERPLASIA,LYMPHOID,MEDULLA | 2 2 1 2 2| |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + A + + + + + + + + + + + + + + + M + M + + | |
GALACTOCELE | | |
LACTATION | | |
SKIN | + + + + + + + + + + + + A + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY | 1 3 1 1 1 | |
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 1 1 2 2 3 3 2 1 1 4 3 2 3 1 3| |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 60
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:52.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 5| 2| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 4| 6| 5| 9| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 4| 0| 2| 2| 8| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 2| 2| 2| 3| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| S R R|
| 6| 6| 7| 8| 2| 1| 1| 1| 1| 1| 2| 2| 2| 4| 4| 5| 5| 5| 2| 2| 2| 2| 2| 2| 2| U V I|
100MG F3MTH 08 8 | 5| 7| 5| 0| 2| 5| 6| 7| 8| 9| 0| 1| 2| 8| 9| 0| 1| 2| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
SKELETAL MUSCLE | + + + A + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 1 2 1 1 1 1 1 1 2 1 1| |
PERIPHERAL NERVE | + + + A + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + + + | |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + + + + + + + + + + + + + + + + + + + + + + | |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CONGESTION | 3 | |
HEMORRHAGE | 2 | |
HYPERPLASIA,ALVEOLAR EPITHELIUM | 3 2 | |
INFILTRATION CELLULAR,HISTIOCYTIC | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 2| |
INFLAMMATION | 2 1 1 1 | |
NOSE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
TRACHEA | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + A A + + + + + + + + + + + + + + + + + + + + | |
INFLAMMATION | 2 | |
HARDERIAN GLAND | + + + A + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 2 | |
HYPERPLASIA | 4 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 61
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:35:52.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 5| 2| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 4| 6| 5| 9| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 4| 0| 2| 2| 8| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 2| 2| 2| 3| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| S R R|
| 6| 6| 7| 8| 2| 1| 1| 1| 1| 1| 2| 2| 2| 4| 4| 5| 5| 5| 2| 2| 2| 2| 2| 2| 2| U V I|
100MG F3MTH 08 8 | 5| 7| 5| 0| 2| 5| 6| 7| 8| 9| 0| 1| 2| 8| 9| 0| 1| 2| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 | |
LACRIMAL GLAND | + + M + M + + + + + M M + + + + + + + + + + + + M | |
APOPTOSIS | 1 | |
ATROPHY | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 1 1 2 1 1 1 1 1 | |
NECROSIS | | |
ZYMBAL'S GLAND | + + + + + + + + + + + + + + + + + + M + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AMYLOID DEPOSITION,GLOMERULUS | 4 | |
CYST,RENAL TUBULE | 2 1 1 1 1 | |
INFARCT | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 2 1 1 1 3 1 1 1 1 1 2 1 1 1 1 1 2 | |
INFILTRATION CELLULAR,PLASMA CELL | | |
INFLAMMATION,ADVENTITIA | | |
URINARY BLADDER | + + + A M + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 1 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 62
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:01.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9| S R R|
| 7| 7| 7| 7| 7| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| U V I|
100MG F3MTH 08 8 | 3| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + M + + M + M + M | 36 |
GALLBLADDER | + + + + + + + + + + + + + + + | 37 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 2 1.0|
INTESTINE LARGE | + + + + + + + + + + + + + + + | 37 |
INTESTINE LARGE,CECUM | + + + + + + + + + + + + + + + | 37 |
INTESTINE LARGE,COLON | + + + + + + + + + + + + + + + | 37 |
INTESTINE LARGE,RECTUM | + + + + + + + + + + + + + + + | 37 |
INFLAMMATION | | 1 3.0|
INTESTINE SMALL | + + + + + + + + + + + + + + + | 37 |
INTESTINE SMALL,DUODENUM | + + + + + + + + + + + + + + + | 37 |
INTESTINE SMALL,ILEUM | + + + M + + + + + + + + + + + | 35 |
HYPERPLASIA,LYMPHOID | 2 2 | 2 2.0|
INTESTINE SMALL,JEJUNUM | + + + + + + + + + + + + + + + | 37 |
HYPERPLASIA,LYMPHOID | 2 2 | 2 2.0|
LIVER | + + + + + + + + + + + + + + + | 40 |
APOPTOSIS | 4 | 1 4.0|
ATROPHY | | 1 1.0|
EOSINOPHILIC FOCUS | | 1 |
HEMATOPOIETIC CELL PROLIFERATION | | 3 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 2 2 1 1 | 27 1.1|
INFILTRATION CELLULAR,PLASMA CELL | 3 | 1 3.0|
LEUKOCYTOSIS | | 1 1.0|
NECROSIS | 1 1 1 1 1 1 1 1 1 1 | 24 1.0|
TENSION LIPOIDOSIS | X X X X X | 10 |
VACUOLIZATION CYTOPLASMIC | 1 1 1 1 1 1 2 1 1 1 1 | 29 1.2|
MESENTERY | + | 1 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 1 2.0|
PANCREAS | + + + + + + + + + + + + + + + | 40 |
ATROPHY | | 1 1.0|
ECTASIA,DUCT | | 1 3.0|
FOCAL CELLULAR CHANGE | | 2 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 2 2 1 1 | 21 1.1|
INFLAMMATION | 4 | 1 4.0|
SALIVARY GLANDS | + + + + + + + + + + + + + + + | 40 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 3 2 1 2 1 1 2 1 1 1 1 | 33 1.2|
INFLAMMATION | 3 | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 63
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:02.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9| S R R|
| 7| 7| 7| 7| 7| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| U V I|
100MG F3MTH 08 8 | 3| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
MINERALIZATION | 2 | 1 2.0|
STOMACH | + + + + + + + + + + + + + + + | 37 |
STOMACH,FORESTOMACH | + + + + + + + + + + + + + + + | 37 |
STOMACH,GLANDULAR | + + + + + + + + + + + + + + + | 37 |
CYST | 2 | 1 2.0|
TONGUE | + + + + + + + + + + + + + + + | 39 |
INFILTRATION CELLULAR,MAST CELL | | 2 2.0|
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + + + + + + + + | 36 |
BLOOD VESSEL,AORTA | + + + + + + + + + + + + + + + | 36 |
HEART | + + + + + + + + + + + + + + + | 40 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
INFLAMMATION | | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + + + | 40 |
INFLAMMATION,EXTRA ADRENAL TISSUE | 4 | 1 4.0|
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + + + | 40 |
HYPERPLASIA,SPINDLE CELL | 2 2 2 2 3 2 2 3 2 2 4 1 2 1 2 | 37 2.0|
VACUOLIZATION CYTOPLASMIC | | 1 1.0|
ADRENAL GLAND,MEDULLA | + + + + + + + + + + + + + + + | 40 |
CONGESTION | 2 | 1 2.0|
VACUOLIZATION CYTOPLASMIC | 2 | 1 2.0|
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + | 40 |
PARATHYROID GLAND | M + + + + + + + + + + + + + + | 31 |
PITUITARY GLAND | + + + + + + + M + + + + + + + | 36 |
ANGIECTASIS | | 1 1.0|
CYST | 2 | 1 2.0|
HYPERPLASIA,PARS DISTALIS | 2 4 | 3 3.0|
THYROID GLAND | + + + + + + + + + + + + + + + | 40 |
CYST,FOLLICLE | | 1 1.0|
HYPERPLASIA,FOLLICULAR CELL | 1 | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 | 2 1.5|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 64
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:02.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9| S R R|
| 7| 7| 7| 7| 7| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| U V I|
100MG F3MTH 08 8 | 3| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
INFLAMMATION | | 1 1.0|
ULTIMOBRANCHIAL CYST | 2 3 2 2 2 | 9 2.1|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + + + + + + + + + M + + + + | 37 |
ATROPHY | 4 3 3 3 3 4 3 3 4 2 3 3 4 4 | 35 3.3|
INFLAMMATION | | 1 2.0|
OVARY | + + + + + + + + + + + + + + + | 40 |
ATROPHY | X X X X X X X X X X X X X X | 33 |
CYST | X X | 6 |
CYST,PERIOVARIAN TISSUE | X X X X | 12 |
HEMATOCYST | X | 2 |
HYPERPLASIA,ADENOMATOUS | 2 3 | 3 2.6|
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 3 2 | 3 2.6|
UTERUS | + + + + + + + + + + + + + + + | 40 |
ATROPHY | | 2 3.0|
DILATATION | | 1 4.0|
FIBROSIS | | 1 2.0|
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 3 2 2 3 3 2 3 2 3 2 3 3 3 1 3 | 32 2.3|
THROMBUS | | 1 2.0|
VAGINA | + + + M + + + + + + + + + + + | 38 |
ATROPHY | | 2 3.0|
DYSPLASIA | 3 | 1 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 2 1.0|
INFLAMMATION | 4 | 2 3.0|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + | 39 |
HYPERPLASIA | 4 2 | 6 3.0|
HYPOPLASIA | | 1 2.0|
PIGMENTATION | | 1 3.0|
LYMPH NODE | + + + + + + + + + + + + + + + | 40 |
HYPERPLASIA,PLASMA CELL,MEDIASTINAL | 4 | 1 4.0|
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + | 40 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 65
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:02.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9| S R R|
| 7| 7| 7| 7| 7| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| U V I|
100MG F3MTH 08 8 | 3| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
ATROPHY | | 1 3.0|
HEMATOPOIETIC CELL PROLIFERATION | | 1 2.0|
HEMORRHAGE | | 1 1.0|
HYPERPLASIA,LYMPHOID | 2 3 | 5 2.2|
HYPERPLASIA,PLASMA CELL | 4 | 1 4.0|
INFLAMMATION | | 1 2.0|
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + + + + | 40 |
ATROPHY | | 2 3.5|
FIBROSIS | | 1 2.0|
HEMORRHAGE | | 1 4.0|
HYPERPLASIA,LYMPHOID | 2 | 2 2.5|
HYPERPLASIA,PLASMA CELL | 4 | 1 4.0|
SPLEEN | + + + + + + + + + + + + + + + | 40 |
ATROPHY | 3 | 2 3.5|
HEMATOPOIETIC CELL PROLIFERATION | 4 | 4 3.5|
HYPERPLASIA,LYMPHOID | 1 3 3 3 | 10 2.1|
HYPERPLASIA,PLASMA CELL,RED PULP | 4 | 1 4.0|
THYMUS | + + + + + + + + + + + + + M + | 33 |
ATROPHY,CORTEX | 3 2 3 2 4 2 3 3 2 | 24 2.8|
HYPERPLASIA,LYMPHOID,MEDULLA | 3 2 2 2 2 2 3 2 | 13 2.0|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + + + + + + + + + M + + | 36 |
GALACTOCELE | 2 | 1 2.0|
LACTATION | 2 | 1 2.0|
SKIN | + + + + + + + + + + + + + + + | 39 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + | 40 |
BONE,FEMUR | + + + + + + + + + + + + + + + | 40 |
FIBROUS OSTEODYSTROPHY | 2 1 1 1 | 9 1.3|
BONE,STERNUM | + + + + + + + + + + + + + + + | 40 |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 2 1 2 3 1 2 2 2 4 3 1 2 4 | 28 2.1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 66
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:02.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9| S R R|
| 7| 7| 7| 7| 7| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| U V I|
100MG F3MTH 08 8 | 3| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
SKELETAL MUSCLE | + + + + + + + + + + + + + + + | 39 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 2 1.5|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + | 40 |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + | 40 |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + | 40 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 2 1.0|
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 1 1 1 1 1 1 | 21 1.0|
PERIPHERAL NERVE | + + + M + + + + + + + + + + + | 38 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
SPINAL CORD | + + + + + + + + + + + + + + + | 40 |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + | 40 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + + + + + + + + + + + + | 40 |
LUNG | + + + + + + + + + + + + + + + | 40 |
CONGESTION | | 1 3.0|
HEMORRHAGE | | 1 2.0|
HYPERPLASIA,ALVEOLAR EPITHELIUM | | 2 2.5|
INFILTRATION CELLULAR,HISTIOCYTIC | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 2 1 2 1 1 1 1 1 2 1 | 30 1.1|
INFLAMMATION | | 4 1.2|
NOSE | + + + + + + + + + + + + + + + | 40 |
TRACHEA | + + + + + + + + + + + + + + + | 40 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + + + + + + + + | 38 |
INFLAMMATION | | 1 2.0|
HARDERIAN GLAND | + + + + + + + + + + + + + + M | 38 |
ATROPHY | | 1 2.0|
HYPERPLASIA | 4 | 2 4.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 67
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:02.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9| S R R|
| 7| 7| 7| 7| 7| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| U V I|
100MG F3MTH 08 8 | 3| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 | 13 1.0|
LACRIMAL GLAND | + + + M + + + + + + + + + M + | 33 |
APOPTOSIS | | 1 1.0|
ATROPHY | 2 | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 1 1 3 1 1 1 1 | 21 1.2|
NECROSIS | 2 | 1 2.0|
ZYMBAL'S GLAND | + + + + + + + M + + + + + + + | 38 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + | 40 |
AMYLOID DEPOSITION,GLOMERULUS | | 1 4.0|
CYST,RENAL TUBULE | 1 1 1 1 | 9 1.1|
INFARCT | | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 2 1 1 2 1 1 1 1 | 31 1.2|
INFILTRATION CELLULAR,PLASMA CELL | 2 | 1 2.0|
INFLAMMATION,ADVENTITIA | 2 | 1 2.0|
URINARY BLADDER | + + + M + + + + + + + + + + + | 37 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 2 2 2 1 1 2 1 1 1 2 1 | 31 1.2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 68
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:15.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 0| 4| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 8| 9| 7| 7| 2| 8| 8| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 0| 5| 4| 6| 0| 4| 2| 1| 5| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 2| 2| 2| 3| 3| 3| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| S R R|
| 7| 9| 9| 6| 7| 8| 1| 2| 9| 0| 1| 1| 1| 1| 1| 4| 4| 4| 4| 4| 4| 4| 1| 1| 1| U V I|
100MG F6MTH 09 9 | 7| 2| 4| 4| 0| 8| 3| 1| 0| 9| 0| 1| 2| 3| 4| 1| 2| 3| 4| 5| 6| 7| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DILATATION | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
GALLBLADDER | + A + + + + + + + + + + + + + + + + + + + + + M + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | |
INFLAMMATION | | |
INTESTINE LARGE | + A + + + + A + A + + + + + + + + + + + + + + + + | |
INTESTINE LARGE,CECUM | + A + + + + A + A + + + + + + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | 2 | |
INTESTINE LARGE,COLON | + A + + + + A + A + + + + + + + + + + + + + + + + | |
INTESTINE LARGE,RECTUM | + A + + + + A + A + + + + + + + + + + + + + + + + | |
INTESTINE SMALL | + A + + + + A + A + + + + + + + + + + + + + + + + | |
INTESTINE SMALL,DUODENUM | + A + + + + A + A + + + + + + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | | |
INTESTINE SMALL,ILEUM | + A + + + + A + A + + + + + + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | 3 | |
INTESTINE SMALL,JEJUNUM | + A + + + + A + A + + + + + + + + + + + + + + + + | |
HYPERPLASIA,GOBLET CELL | | |
HYPERPLASIA,LYMPHOID | 2 | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BASOPHILIC FOCUS | X | |
DEGENERATION,CENTRILOBULAR | 2 | |
EOSINOPHILIC FOCUS | X X | |
HEMATOPOIETIC CELL PROLIFERATION | 2 2 2 1 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 2 3 1 1 1 1 1 1 2 2 1 1 1 2| |
NECROSIS | 1 1 1 1 1 1 1 1 1 1 1 2 1 1| |
NECROSIS,COAGULATIVE | 2 2 2 | |
TENSION LIPOIDOSIS | X X X X X | |
VACUOLIZATION CYTOPLASMIC | 2 1 1 1 2 1 1 1 1 2 1 1 1 1 1| |
MESENTERY | + | |
NECROSIS,FAT | | |
PANCREAS | + A + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 4 | |
FOCAL CELLULAR CHANGE | 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 1 1 1 1 1 2 2 1| |
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 69
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:16.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 0| 4| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 8| 9| 7| 7| 2| 8| 8| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 0| 5| 4| 6| 0| 4| 2| 1| 5| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 2| 2| 2| 3| 3| 3| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| S R R|
| 7| 9| 9| 6| 7| 8| 1| 2| 9| 0| 1| 1| 1| 1| 1| 4| 4| 4| 4| 4| 4| 4| 1| 1| 1| U V I|
100MG F6MTH 09 9 | 7| 2| 4| 4| 0| 8| 3| 1| 0| 9| 0| 1| 2| 3| 4| 1| 2| 3| 4| 5| 6| 7| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ATROPHY | 3 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 2 2 2 1 2 2 1 1 1 2 2 2 1 1 1 1 2| |
STOMACH | + A + + + + A + + + + + + + + + + + + + + + + + + | |
STOMACH,FORESTOMACH | + A + + + + A + + + + + + + + + + + + + + + + + + | |
HYPERKERATOSIS | | |
STOMACH,GLANDULAR | + A + + + + A + + + + + + + + + + + + + + + + + + | |
CYST | 2 | |
INFLAMMATION | | |
TONGUE | + + + + + + + + A + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | M M + + + + + + + + + + + + + + + + + + + + + + + | |
BLOOD VESSEL,AORTA | M M + + + + + + + + + + + + + + + + + + + + + + + | |
HEART | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CARDIOMYOPATHY | 2 | |
INFLAMMATION | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + A + + + + + M A + + + + + + + + + + + + + + + + | |
ADRENAL GLAND,CORTEX | + A + + + + + M A + + + + + + + + + + + + + + + + | |
DEGENERATION,FATTY | 2 | |
ECTOPIC TISSUE | X | |
FOCAL CELLULAR CHANGE | 3 | |
HYPERPLASIA,SPINDLE CELL | 2 2 1 1 2 2 2 2 2 2 1 3 2 4 1 3 2 2 1 2 2| |
ADRENAL GLAND,MEDULLA | + A + + + + + M A + + + + + + + + + + + + + + + + | |
CYTOPLASMIC ALTERATION | | |
ISLETS, PANCREATIC | + A + + + + A + M + + + + + + + + + + + + + + + + | |
PARATHYROID GLAND | + + M + + M + + + + + + + + + + + M + M + + + + M | |
ECTOPIC THYMUS | X | |
PITUITARY GLAND | M + + M + + + + + + + + + + + + + + + + + M + + + | |
HYPERPLASIA,PARS DISTALIS | | |
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DEGENERATION | | |
GOITER ADENOMATOUS | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 70
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:16.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 0| 4| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 8| 9| 7| 7| 2| 8| 8| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 0| 5| 4| 6| 0| 4| 2| 1| 5| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 2| 2| 2| 3| 3| 3| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| S R R|
| 7| 9| 9| 6| 7| 8| 1| 2| 9| 0| 1| 1| 1| 1| 1| 4| 4| 4| 4| 4| 4| 4| 1| 1| 1| U V I|
100MG F6MTH 09 9 | 7| 2| 4| 4| 0| 8| 3| 1| 0| 9| 0| 1| 2| 3| 4| 1| 2| 3| 4| 5| 6| 7| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
HYPERPLASIA,FOLLICULAR CELL | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
ULTIMOBRANCHIAL CYST | 2 2 2 2 2 2 | |
------------------------------------------------------------------------------------------------------------------------------------
GENERAL BODY SYSTEM
TISSUE NOS | + | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + + + + + M M M + + + + + + + + + M + + M + + + | |
ATROPHY | 2 4 3 3 4 4 4 4 4 3 2 3 3 3 3 3| |
INFLAMMATION | 2 1 | |
OVARY | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | X X X X X X X X X X X X X X X X X X X X X X | |
CYST | X X X X | |
CYST,PERIOVARIAN TISSUE | X X X X | |
HEMATOCYST | X X X | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
OVOTESTIS | | |
UTERUS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 3 | |
DILATATION | 4 2 | |
FIBROSIS | | |
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 2 4 2 4 2 2 1 3 2 3 2 1 1 | |
VAGINA | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 3 | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DEPLETION | 2 | |
HYPERPLASIA | 3 4 4 | |
PIGMENTATION | 2 | |
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,PLASMA CELL | | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 71
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:16.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 0| 4| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 8| 9| 7| 7| 2| 8| 8| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 0| 5| 4| 6| 0| 4| 2| 1| 5| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 2| 2| 2| 3| 3| 3| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| S R R|
| 7| 9| 9| 6| 7| 8| 1| 2| 9| 0| 1| 1| 1| 1| 1| 4| 4| 4| 4| 4| 4| 4| 1| 1| 1| U V I|
100MG F6MTH 09 9 | 7| 2| 4| 4| 0| 8| 3| 1| 0| 9| 0| 1| 2| 3| 4| 1| 2| 3| 4| 5| 6| 7| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
INFLAMMATION | | |
LYMPH NODE,MANDIBULAR | + + + + + M + + + + + + + + + + + + + + + + + + + | |
ATROPHY | | |
HEMORRHAGE | | |
HYPERPLASIA,LYMPHOID | 3 2 2 2 4 3 2 2 | |
LYMPH NODE,MESENTERIC | + A + + + + M + + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | | |
HEMORRHAGE | 2 | |
HYPERPLASIA,LYMPHOID | 3 2 | |
HYPERPLASIA,PLASMA CELL | | |
HYPERPLASIA,RETICULUM CELL | 2 | |
INFLAMMATION | 3 | |
SPLEEN | + A + + + + + + + + + + + + + + + + + + + + + + + | |
AMYLOID DEPOSITION | | |
HEMATOPOIETIC CELL PROLIFERATION | 4 3 3 3 3 3 3| |
HYPERPLASIA,LYMPHOID | 1 2 3 2 2 2 3 1| |
THYMUS | + M M M M + M + + + + + + + + + + + + M + + + M + | |
ATROPHY,CORTEX | 3 4 4 4 3 3 3 2 2 2 3 2 3 | |
CYST | | |
ECTOPIC PARATHYROID GLAND | X | |
HYPERPLASIA,LYMPHOID,MEDULLA | 3 2 2 3 1| |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + + + + M + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
LACTATION | 2 | |
METAPLASIA,SQUAMOUS | X | |
SKIN | + A + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 72
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:16.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 0| 4| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 8| 9| 7| 7| 2| 8| 8| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 0| 5| 4| 6| 0| 4| 2| 1| 5| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 2| 2| 2| 3| 3| 3| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| S R R|
| 7| 9| 9| 6| 7| 8| 1| 2| 9| 0| 1| 1| 1| 1| 1| 4| 4| 4| 4| 4| 4| 4| 1| 1| 1| U V I|
100MG F6MTH 09 9 | 7| 2| 4| 4| 0| 8| 3| 1| 0| 9| 0| 1| 2| 3| 4| 1| 2| 3| 4| 5| 6| 7| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
FIBROUS OSTEODYSTROPHY | 2 2 | |
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 3 2 1 1 2 3 3 1 2 3 1 2 | |
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 1 1 1 1 1 1 1 2 1 1 1| |
PERIPHERAL NERVE | + + + + + + + + A + + + + + + + + + + + + + + + + | |
INFLAMMATION | | |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + + + | |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | M + M + M M + M + + + + + + + + + + + + + + + + + | |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HEMORRHAGE | 3 | |
HYPERPLASIA,ALVEOLAR EPITHELIUM | 2 | |
INFILTRATION CELLULAR,HISTIOCYTIC | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 1 1 1 2 1 1 2 2 1 2 1 1 2| |
INFLAMMATION | 4 | |
NOSE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DILATATION,GLANDS | | |
TRACHEA | + + + + + + + + + + M + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + A A A + + A A A + + + + + + + + + + + + + + + + | |
HARDERIAN GLAND | + + + + + + + + A + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1| |
LACRIMAL GLAND | + + + M + + + + M + + M + + M + + + M + + + M + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 73
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:16.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 0| 4| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 8| 9| 7| 7| 2| 8| 8| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 0| 5| 4| 6| 0| 4| 2| 1| 5| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 2| 2| 2| 3| 3| 3| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| S R R|
| 7| 9| 9| 6| 7| 8| 1| 2| 9| 0| 1| 1| 1| 1| 1| 4| 4| 4| 4| 4| 4| 4| 1| 1| 1| U V I|
100MG F6MTH 09 9 | 7| 2| 4| 4| 0| 8| 3| 1| 0| 9| 0| 1| 2| 3| 4| 1| 2| 3| 4| 5| 6| 7| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 2 1 1 1 2 1 | |
ZYMBAL'S GLAND | M + + + + M + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + A + + + + + + + + + + + + + + + + + + + + + + + | |
AMYLOID DEPOSITION,GLOMERULUS | 4 | |
CYST,RENAL TUBULE | 1 1 1 1 1 1 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 2 1 2 1 1 1 1 1 1| |
NECROSIS,COAGULATIVE | 1 | |
NEPHROPATHY | 1 | |
URINARY BLADDER | + + + + + + + + A + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 2 1 1 2 1 1 2 1 1 1 1 2 1 1| |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 74
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:24.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 7| 7| 7| 7| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| S R R|
| 1| 1| 9| 9| 9| 9| 9| 3| 3| 3| 3| 3| 3| 4| 4| U V I|
100MG F6MTH 09 9 | 8| 9| 1| 2| 3| 4| 5| 4| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + + + + + + + | 40 |
DILATATION | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
GALLBLADDER | + + + + M + + + + + M + + + + | 36 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 | 4 1.2|
INFLAMMATION | 1 | 1 1.0|
INTESTINE LARGE | + + + + + + + + + + + + + + + | 37 |
INTESTINE LARGE,CECUM | + + + + + + + + + + + + + + + | 37 |
HYPERPLASIA,LYMPHOID | 2 | 2 2.0|
INTESTINE LARGE,COLON | + + + + + + + + + + + + + + + | 37 |
INTESTINE LARGE,RECTUM | + + + + + + + + + + + + + + + | 37 |
INTESTINE SMALL | + + + + + + + + + + + + + + + | 37 |
INTESTINE SMALL,DUODENUM | + + + + + + + + + + + + + + + | 37 |
HYPERPLASIA,LYMPHOID | 2 | 1 2.0|
INTESTINE SMALL,ILEUM | + + + + + + + + + + + + + + + | 37 |
HYPERPLASIA,LYMPHOID | 2 2 | 3 2.3|
INTESTINE SMALL,JEJUNUM | + + + + + + + + + + + + + + + | 37 |
HYPERPLASIA,GOBLET CELL | 2 | 1 2.0|
HYPERPLASIA,LYMPHOID | 2 | 2 2.0|
LIVER | + + + + + + + + + + + + + + + | 40 |
BASOPHILIC FOCUS | X X | 3 |
DEGENERATION,CENTRILOBULAR | | 1 2.0|
EOSINOPHILIC FOCUS | | 2 |
HEMATOPOIETIC CELL PROLIFERATION | | 5 1.8|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 | 29 1.2|
NECROSIS | 1 1 1 1 1 1 1 | 21 1.0|
NECROSIS,COAGULATIVE | | 3 2.0|
TENSION LIPOIDOSIS | X X X X X | 10 |
VACUOLIZATION CYTOPLASMIC | 1 1 1 1 1 1 1 1 1 1 1 1 1 | 28 1.1|
MESENTERY | + | 2 |
NECROSIS,FAT | 4 | 1 4.0|
PANCREAS | + + + + + + + + + + + + + + + | 39 |
ATROPHY | | 1 4.0|
FOCAL CELLULAR CHANGE | | 2 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 | 16 1.1|
SALIVARY GLANDS | + + + + + + + + + + + + + + + | 40 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 75
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:25.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 7| 7| 7| 7| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| S R R|
| 1| 1| 9| 9| 9| 9| 9| 3| 3| 3| 3| 3| 3| 4| 4| U V I|
100MG F6MTH 09 9 | 8| 9| 1| 2| 3| 4| 5| 4| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ATROPHY | 4 2 | 3 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 1 1 1 2 2 1 1 1 1 2 1 1 | 35 1.4|
STOMACH | + + + + + + + + + + + + + + + | 38 |
STOMACH,FORESTOMACH | + + + + + + + + + + + + + + + | 38 |
HYPERKERATOSIS | 2 | 1 2.0|
STOMACH,GLANDULAR | + + + + + + + + + + + + + + + | 38 |
CYST | 1 1 | 3 1.3|
INFLAMMATION | 1 | 1 1.0|
TONGUE | + + + + + + + + + + + + + + + | 39 |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | M M + + + + + + + + + + M + + | 35 |
BLOOD VESSEL,AORTA | M M + + + + + + + + + + M + + | 35 |
HEART | + + + + + + + + + + + + + + + | 40 |
CARDIOMYOPATHY | | 1 2.0|
INFLAMMATION | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + + + | 37 |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + + + | 37 |
DEGENERATION,FATTY | | 1 2.0|
ECTOPIC TISSUE | | 1 |
FOCAL CELLULAR CHANGE | 2 | 2 2.5|
HYPERPLASIA,SPINDLE CELL | 1 1 2 2 2 2 2 3 1 3 1 1 2 | 34 1.8|
ADRENAL GLAND,MEDULLA | + + + + + + + + + + + + + + + | 37 |
CYTOPLASMIC ALTERATION | 2 | 1 2.0|
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + | 37 |
PARATHYROID GLAND | + + + + + + M M + + + + + + + | 33 |
ECTOPIC THYMUS | | 1 |
PITUITARY GLAND | + + + + + + + M + + + + + + + | 36 |
HYPERPLASIA,PARS DISTALIS | 2 | 1 2.0|
THYROID GLAND | + + + + + + + + + + + + + + + | 40 |
DEGENERATION | 2 | 1 2.0|
GOITER ADENOMATOUS | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 76
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:25.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 7| 7| 7| 7| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| S R R|
| 1| 1| 9| 9| 9| 9| 9| 3| 3| 3| 3| 3| 3| 4| 4| U V I|
100MG F6MTH 09 9 | 8| 9| 1| 2| 3| 4| 5| 4| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
HYPERPLASIA,FOLLICULAR CELL | 2 | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 2 1.5|
ULTIMOBRANCHIAL CYST | 2 2 | 8 2.0|
------------------------------------------------------------------------------------------------------------------------------------
GENERAL BODY SYSTEM
TISSUE NOS | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + + + + + + M + + + + M + + | 33 |
ATROPHY | 3 3 3 4 3 3 3 3 3 3 4 3 4 | 29 3.2|
INFLAMMATION | | 2 1.5|
OVARY | + + + + + + + + + + M + + + + | 39 |
ATROPHY | X X X X X X X X X X X X | 34 |
CYST | X X | 6 |
CYST,PERIOVARIAN TISSUE | X X | 6 |
HEMATOCYST | X X | 5 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 1 2.0|
OVOTESTIS | 1 | 1 1.0|
UTERUS | + + + + + + + + + + + + + + + | 40 |
ATROPHY | | 2 3.0|
DILATATION | 4 | 3 3.3|
FIBROSIS | 2 | 1 2.0|
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 2 3 2 3 2 4 2 4 2 1 2 | 26 2.3|
VAGINA | + + + + + + + + + + + + + + + | 40 |
ATROPHY | | 2 3.0|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + | 40 |
DEPLETION | | 1 2.0|
HYPERPLASIA | 2 | 4 3.2|
PIGMENTATION | | 1 2.0|
LYMPH NODE | + + + + + + + + + + + + + + + | 40 |
HYPERPLASIA,PLASMA CELL | 4 | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 77
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:25.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 7| 7| 7| 7| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| S R R|
| 1| 1| 9| 9| 9| 9| 9| 3| 3| 3| 3| 3| 3| 4| 4| U V I|
100MG F6MTH 09 9 | 8| 9| 1| 2| 3| 4| 5| 4| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
INFLAMMATION | 2 | 1 2.0|
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + | 39 |
ATROPHY | 3 | 1 3.0|
HEMORRHAGE | 2 | 1 2.0|
HYPERPLASIA,LYMPHOID | 2 2 | 10 2.4|
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + + + + | 38 |
ANGIECTASIS | 4 | 1 4.0|
HEMORRHAGE | | 1 2.0|
HYPERPLASIA,LYMPHOID | 2 2 | 4 2.2|
HYPERPLASIA,PLASMA CELL | 4 | 1 4.0|
HYPERPLASIA,RETICULUM CELL | | 1 2.0|
INFLAMMATION | | 1 3.0|
SPLEEN | + + + + + + + + + + + + + + + | 39 |
AMYLOID DEPOSITION | 2 | 1 2.0|
HEMATOPOIETIC CELL PROLIFERATION | | 7 3.1|
HYPERPLASIA,LYMPHOID | 3 1 1 | 11 1.9|
THYMUS | M + + M + + + + + + + + + + + | 31 |
ATROPHY,CORTEX | 2 3 4 2 3 3 2 | 20 2.8|
CYST | 2 | 1 2.0|
ECTOPIC PARATHYROID GLAND | | 1 |
HYPERPLASIA,LYMPHOID,MEDULLA | 2 2 2 3 2 3 2 | 12 2.2|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + + + + + + + + M + + + | 38 |
HYPERPLASIA | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
LACTATION | | 1 2.0|
METAPLASIA,SQUAMOUS | | 1 |
SKIN | + + + + + + + + + + + + + + + | 39 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + | 40 |
BONE,FEMUR | + + + + + + + + + + + + + + + | 40 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 78
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:25.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 7| 7| 7| 7| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| S R R|
| 1| 1| 9| 9| 9| 9| 9| 3| 3| 3| 3| 3| 3| 4| 4| U V I|
100MG F6MTH 09 9 | 8| 9| 1| 2| 3| 4| 5| 4| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
FIBROUS OSTEODYSTROPHY | 1 1 1 | 5 1.4|
BONE,STERNUM | + + + + + + + + + + + + + + + | 40 |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 1 2 1 2 2 1 4 1 3 2 2 2 2 | 25 1.9|
SKELETAL MUSCLE | + + + + + + + + + + + + + + + | 40 |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + | 40 |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + | 40 |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + | 40 |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 1 1 1 1 1 1 1 1 | 23 1.0|
PERIPHERAL NERVE | + + + + + + + + + + + + + + + | 39 |
INFLAMMATION | 1 | 1 1.0|
SPINAL CORD | + + + + + + + + + + + + + + + | 40 |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + | 40 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + + + + + + + + M + + + | 34 |
LUNG | + + + + + + + + + + + + + + + | 40 |
HEMORRHAGE | | 1 3.0|
HYPERPLASIA,ALVEOLAR EPITHELIUM | | 1 2.0|
INFILTRATION CELLULAR,HISTIOCYTIC | 1 | 2 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 2 1 2 1 1 2 1 1 | 29 1.3|
INFLAMMATION | 1 | 2 2.5|
NOSE | + + + + + + + + + + + + + + + | 40 |
DILATATION,GLANDS | 3 | 1 3.0|
TRACHEA | + + + + + + + + + + + + + + + | 39 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + + + + + + + + | 34 |
HARDERIAN GLAND | + + + + + + M + + + + + + + + | 38 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 | 16 1.0|
LACRIMAL GLAND | + + + + + + M + + + + + + + + | 33 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 79
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:25.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 7| 7| 7| 7| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| S R R|
| 1| 1| 9| 9| 9| 9| 9| 3| 3| 3| 3| 3| 3| 4| 4| U V I|
100MG F6MTH 09 9 | 8| 9| 1| 2| 3| 4| 5| 4| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 1 1 2 1 1 1 1 | 17 1.2|
ZYMBAL'S GLAND | + + M M + + + + + + + + + + + | 36 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + | 39 |
AMYLOID DEPOSITION,GLOMERULUS | | 1 4.0|
CYST,RENAL TUBULE | 1 | 9 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 2 1 1 2 1 | 31 1.1|
NECROSIS,COAGULATIVE | | 1 1.0|
NEPHROPATHY | 1 | 2 1.0|
URINARY BLADDER | + + + + + + + + + + + + + + + | 39 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 2 1 1 1 1 1 2 1 | 33 1.2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 80
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:39.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 6| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 9| 9| 1| 1| 3| 6| 9| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 3| 1| 6| 9| 9| 8| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 1| 1| 2| 3| 3| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| S R R|
| 5| 9| 0| 0| 7| 1| 1| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 4| 0| 1| 1| U V I|
100MG F12MTH 10 10 | 8| 8| 2| 5| 6| 4| 6| 2| 3| 4| 5| 6| 7| 8| 3| 4| 5| 6| 7| 8| 9| 0| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + A + + + + + + + + + + + + + + + + + + + + + + | |
GALLBLADDER | + A + A A + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 | |
INTESTINE LARGE | A + A + A A A + + M + + + + + + + + + + + + + + + | |
INTESTINE LARGE,CECUM | A A A A A A A + + M + + + + + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | | |
INTESTINE LARGE,COLON | A + A + A A A + + M + + + + + + + + + + + + + + + | |
HYPERPLASIA,GOBLET CELL | 3 | |
HYPERPLASIA,LYMPHOID | | |
INTESTINE LARGE,RECTUM | A + A M A A A + + M + + + + + + + + + + + + + + M | |
INTESTINE SMALL | A A A A A A A + + + + + + + + + + + + + + + + + + | |
INTESTINE SMALL,DUODENUM | A A A A A A A + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
INTESTINE SMALL,ILEUM | A A A A A A A + + M + + + + + + + + + + + + + + M | |
HYPERPLASIA,LYMPHOID | 4 | |
INTESTINE SMALL,JEJUNUM | A A A A A A A + + M + + + + + + + + + + + + + + + | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BASOPHILIC FOCUS | | |
CLEAR CELL FOCUS | X | |
DEGENERATION,CYSTIC | 3 | |
DEGENERATION,FATTY | | |
EOSINOPHILIC FOCUS | X X X | |
HEMATOPOIETIC CELL PROLIFERATION | 2 | |
HYPERPLASIA,KUPFFER CELL | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 2 1 1 1 1 1 1 1 1 1 2| |
MIXED CELL FOCUS | | |
NECROSIS | 1 1 1 1 1 1 1 1 1 1 1 1 1 | |
NECROSIS,COAGULATIVE | | |
TENSION LIPOIDOSIS | X X X | |
VACUOLIZATION CYTOPLASMIC | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 | |
PANCREAS | + + A + A + A + + + + + + + + + + + + + + + + + + | |
FOCAL CELLULAR CHANGE | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1| |
SALIVARY GLANDS | + + + + + + M + + + + + + + + + + + + + + + + + + | |
ATROPHY | 2 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 2 1 2 1 1 1 1 1 1 1 1 1 1 1| |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 81
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:40.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 6| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 9| 9| 1| 1| 3| 6| 9| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 3| 1| 6| 9| 9| 8| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 1| 1| 2| 3| 3| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| S R R|
| 5| 9| 0| 0| 7| 1| 1| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 4| 0| 1| 1| U V I|
100MG F12MTH 10 10 | 8| 8| 2| 5| 6| 4| 6| 2| 3| 4| 5| 6| 7| 8| 3| 4| 5| 6| 7| 8| 9| 0| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
MINERALIZATION | | |
STOMACH | + + A A A + A + + + + + + + + + + + + + + + + + + | |
STOMACH,FORESTOMACH | A + A A A + A + + + + + + + + + + + + + + + + + + | |
HYPERKERATOSIS | 2 | |
HYPERPLASIA | | |
ULCER | 3 | |
STOMACH,GLANDULAR | + + A A A + A + + + + + + + + + + + + + + + + + + | |
CYST | 1 1 | |
HYPERPLASIA | 1 | |
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + M + + + + + + + + + + + + + + + + + + | |
BLOOD VESSEL,AORTA | + + + + + + M + + + + + + + + + + + + + + + + + + | |
HEART | + A + + + + + + + + + + + + + + + + + + + + + + + | |
CONGESTION | 3 | |
DILATATION | 4 | |
HEMORRHAGE,VALVE | | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + A M + + A + + + + + + + + + + + + + + + + + + | |
ADRENAL GLAND,CORTEX | + + A M + + A + + + + + + + + + + + + + + + + + + | |
CONGESTION | 3 | |
DEGENERATION,FATTY | | |
HYPERPLASIA,SPINDLE CELL | 2 2 1 2 2 2 2 2 2 2 3 2 2 2 1 1 2 2| |
VACUOLIZATION CYTOPLASMIC | 2 | |
ADRENAL GLAND,MEDULLA | + + A M + + A + + + + + + + + + + + + + + + + + + | |
CONGESTION | 3 | |
ISLETS, PANCREATIC | + + A + A + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
PARATHYROID GLAND | + + A + M + + + + + + + M + + + + + + + + + + + + | |
ECTOPIC THYMUS | | |
PITUITARY GLAND | + + A M + + + + + + + + M + + + + + + + M + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 82
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:40.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 6| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 9| 9| 1| 1| 3| 6| 9| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 3| 1| 6| 9| 9| 8| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 1| 1| 2| 3| 3| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| S R R|
| 5| 9| 0| 0| 7| 1| 1| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 4| 0| 1| 1| U V I|
100MG F12MTH 10 10 | 8| 8| 2| 5| 6| 4| 6| 2| 3| 4| 5| 6| 7| 8| 3| 4| 5| 6| 7| 8| 9| 0| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
CYST | 2 | |
HYPERPLASIA,PARS DISTALIS | 2 | |
THYROID GLAND | + + A + + + + + + + + + + + + + + + + + + + + + + | |
CYST,FOLLICLE | 2 | |
DEGENERATION | | |
ECTOPIC THYMUS | X | |
HYPERPLASIA,FOLLICULAR CELL | | |
HYPERTROPHY,FOLLICULAR CELL | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
ULTIMOBRANCHIAL CYST | 2 2 2 2 | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + A + + + M + + + + + M + + + + + + + M + + M + | |
ATROPHY | 2 4 3 3 3 3 3 3 3 3 4 3 3 3 3 3 3 3 3| |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
OVARY | + + M + + + M + + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | | |
ATROPHY | X X X X X X X X X X X X X X X X X X X | |
CYST | X X X | |
CYST,PERIOVARIAN TISSUE | X X X X X X | |
HEMATOCYST | X | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
MINERALIZATION | | |
UTERUS | + + A + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 | |
DILATATION | | |
ECTASIA,VEIN | | |
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 4 1 3 2 3 3 2 3 4 3 2 3 2 2 4 3| |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
INFLAMMATION | 2 | |
VAGINA | + A A + A + + + + + + + + + + + + + + + + + + + + | |
METAPLASIA | | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 83
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:40.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 6| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 9| 9| 1| 1| 3| 6| 9| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 3| 1| 6| 9| 9| 8| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 1| 1| 2| 3| 3| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| S R R|
| 5| 9| 0| 0| 7| 1| 1| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 4| 0| 1| 1| U V I|
100MG F12MTH 10 10 | 8| 8| 2| 5| 6| 4| 6| 2| 3| 4| 5| 6| 7| 8| 3| 4| 5| 6| 7| 8| 9| 0| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + A A + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | 3 3 3 | |
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
LYMPH NODE,MANDIBULAR | + + + + + + M + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | 2 | |
LYMPH NODE,MESENTERIC | + + + + A + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | | |
CONGESTION,SINUS | | |
HEMORRHAGE | 2 | |
HYPERPLASIA,LYMPHOID | 2 3 | |
SPLEEN | + + + + A + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 2 | |
CONGESTION | 1 2| |
ERYTHROPHAGOCYTOSIS | 1 | |
HEMATOPOIETIC CELL PROLIFERATION | 4 4 | |
HYPERPLASIA,LYMPHOID | 1 2 1 3 1 2 2 1 | |
THYMUS | + + A M + M M + + + + + + + + + + + M + + + + + M | |
ATROPHY,CORTEX | 3 3 4 3 2 2 3 2 3 4 4 3 2 4 3 3 | |
CONGESTION | 2 | |
ECTOPIC PARATHYROID GLAND | X | |
HYPERPLASIA,LYMPHOID,MEDULLA | 2 2 | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + A + M + + A + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | 2| |
SKIN | + + M + + + A + + + + + + + + + + + + + + + + + + | |
ALOPECIA | 4 | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DEGENERATION,CARTILAGE | | |
FIBROUS OSTEODYSTROPHY | 3 2 3 1 1| |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 84
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:40.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 6| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 9| 9| 1| 1| 3| 6| 9| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 3| 1| 6| 9| 9| 8| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 1| 1| 2| 3| 3| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| S R R|
| 5| 9| 0| 0| 7| 1| 1| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 4| 0| 1| 1| U V I|
100MG F12MTH 10 10 | 8| 8| 2| 5| 6| 4| 6| 2| 3| 4| 5| 6| 7| 8| 3| 4| 5| 6| 7| 8| 9| 0| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 3 3 4 1 1 1 1 3 2 2 2 1 3 3 2 3 2| |
SKELETAL MUSCLE | + + + + + + M + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 1 1 1 1 1 1 1 1 1 1 1 1| |
PERIPHERAL NERVE | + + + + + + M + + + + + M + + + + + + + + + + + + | |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + + M | |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + + M | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + M A M M + + + + + + + M + + + + + + + + + + + + | |
CONCRETION | | |
CRYSTALS | | |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CONGESTION | 4 | |
GIANT CELL | | |
HEMORRHAGE | | |
HYPERPLASIA,ALVEOLAR EPITHELIUM | 1 1 | |
INFILTRATION CELLULAR,HISTIOCYTIC | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1| |
INFLAMMATION | | |
THROMBUS,CAPILLARY | 4 | |
NOSE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
TRACHEA | + + A + + + + + + + + + + + + + + + + + + + + + + | |
CYST | 2 | |
FOREIGN BODY | X | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 85
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:40.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 6| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 9| 9| 1| 1| 3| 6| 9| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 3| 1| 6| 9| 9| 8| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 1| 1| 2| 3| 3| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| S R R|
| 5| 9| 0| 0| 7| 1| 1| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 4| 0| 1| 1| U V I|
100MG F12MTH 10 10 | 8| 8| 2| 5| 6| 4| 6| 2| 3| 4| 5| 6| 7| 8| 3| 4| 5| 6| 7| 8| 9| 0| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
EYE | A A A + A A + + + + + + + + + + + + + + + + + + + | |
HARDERIAN GLAND | + + A + + + M + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 | |
INFLAMMATION | | |
LACRIMAL GLAND | + M + + + + M + + + + + M + + + + + + + + + + + M | |
ATROPHY | 2 | |
CYTOMEGALY | | |
ECTASIA,DUCT | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 | |
ZYMBAL'S GLAND | + + + + + M M + + + + + + M + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + A + + + A + + + + + + + + + + + + + + + + + + | |
AMYLOID DEPOSITION,GLOMERULUS | 3 | |
CYST,RENAL TUBULE | 1 1 1 1 1 1 | |
GLOMERULOSCLEROSIS | 3 | |
HYDRONEPHROSIS | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 2 1 1 1 1 1 1 1 1 1 1 1 1 3 2 1| |
NEPHROPATHY | 1 | |
PIGMENTATION,RENAL TUBULE | 1 | |
URINARY BLADDER | + + A + A A A + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 86
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:49.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 7| 7| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| S R R|
| 1| 1| 1| 8| 8| 8| 8| 8| 9| 4| 4| 4| 5| 5| 5| U V I|
100MG F12MTH 10 10 | 2| 3| 4| 5| 6| 7| 8| 9| 0| 7| 8| 9| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + M + + + + + + + + + + + | 38 |
GALLBLADDER | + + + + + + + + + + + + M + + | 36 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 | 6 1.1|
INTESTINE LARGE | + + + + + + + + + + + + + + + | 34 |
INTESTINE LARGE,CECUM | + + + + + + + + + + + + + + + | 32 |
HYPERPLASIA,LYMPHOID | 2 2 2 2 | 4 2.0|
INTESTINE LARGE,COLON | + + + + + + + + + + + + + + + | 34 |
HYPERPLASIA,GOBLET CELL | | 1 3.0|
HYPERPLASIA,LYMPHOID | 2 | 1 2.0|
INTESTINE LARGE,RECTUM | + + + + + + + + + + + + + + + | 32 |
INTESTINE SMALL | + + + + + + + + + + + + + + + | 33 |
INTESTINE SMALL,DUODENUM | + + + + + + + + + + + + + + + | 33 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 1 2.0|
INTESTINE SMALL,ILEUM | + + + + + + + + + + + + + + + | 31 |
HYPERPLASIA,LYMPHOID | 2 | 2 3.0|
INTESTINE SMALL,JEJUNUM | + + + + + + + + + + + + + + + | 32 |
LIVER | + + + + + + + + + + + + + + + | 40 |
BASOPHILIC FOCUS | X X | 2 |
CLEAR CELL FOCUS | X | 2 |
DEGENERATION,CYSTIC | | 1 3.0|
DEGENERATION,FATTY | 2 | 1 2.0|
EOSINOPHILIC FOCUS | | 3 |
HEMATOPOIETIC CELL PROLIFERATION | | 1 2.0|
HYPERPLASIA,KUPFFER CELL | 3 | 1 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 2 1 1 1 1 | 27 1.1|
MIXED CELL FOCUS | X | 1 |
NECROSIS | 1 1 1 1 1 1 1 | 20 1.0|
NECROSIS,COAGULATIVE | 2 | 1 2.0|
TENSION LIPOIDOSIS | X X X X X | 8 |
VACUOLIZATION CYTOPLASMIC | 1 1 1 1 1 1 1 2 1 | 24 1.0|
PANCREAS | + + + + + + + + + + + + + + + | 37 |
FOCAL CELLULAR CHANGE | 1 | 2 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 2 | 16 1.0|
SALIVARY GLANDS | + + + + + + + + + + + + + + + | 39 |
ATROPHY | 1 | 3 1.6|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 1 2 1 2 1 1 1 1 2 | 31 1.1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 87
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:49.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 7| 7| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| S R R|
| 1| 1| 1| 8| 8| 8| 8| 8| 9| 4| 4| 4| 5| 5| 5| U V I|
100MG F12MTH 10 10 | 2| 3| 4| 5| 6| 7| 8| 9| 0| 7| 8| 9| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
MINERALIZATION | 1 | 1 1.0|
STOMACH | + + + + + + + + + + + + + + + | 36 |
STOMACH,FORESTOMACH | + + + + + + + + + + + + + + + | 35 |
HYPERKERATOSIS | 2 | 2 2.0|
HYPERPLASIA | 2 | 1 2.0|
ULCER | | 1 3.0|
STOMACH,GLANDULAR | + + + + + + + + + + + + + + + | 36 |
CYST | | 2 1.0|
HYPERPLASIA | | 1 1.0|
TONGUE | + + + + + + + + + + + + + + + | 40 |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + M + + + + + + M + + + + + | 37 |
BLOOD VESSEL,AORTA | + + M + + + + + + M + + + + + | 37 |
HEART | + + + + + + + + + + + + + + + | 39 |
CONGESTION | | 1 3.0|
DILATATION | | 1 4.0|
HEMORRHAGE,VALVE | X | 1 |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + + + | 37 |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + + + | 37 |
CONGESTION | | 1 3.0|
DEGENERATION,FATTY | 4 | 1 4.0|
HYPERPLASIA,SPINDLE CELL | 2 2 2 2 2 3 2 1 2 1 2 3 1 3 | 32 1.9|
VACUOLIZATION CYTOPLASMIC | | 1 2.0|
ADRENAL GLAND,MEDULLA | + + + + + + + + + + + + + + + | 37 |
CONGESTION | | 1 3.0|
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + | 38 |
HYPERPLASIA | | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
PARATHYROID GLAND | + + + + + + + M + + + + + + + | 36 |
ECTOPIC THYMUS | X | 1 |
PITUITARY GLAND | + + + + + + + M + + + + M + M | 33 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 88
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:49.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 7| 7| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| S R R|
| 1| 1| 1| 8| 8| 8| 8| 8| 9| 4| 4| 4| 5| 5| 5| U V I|
100MG F12MTH 10 10 | 2| 3| 4| 5| 6| 7| 8| 9| 0| 7| 8| 9| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
CYST | | 1 2.0|
HYPERPLASIA,PARS DISTALIS | | 1 2.0|
THYROID GLAND | + + + + + + + + + + + + + + + | 39 |
CYST,FOLLICLE | 2 1 | 3 1.6|
DEGENERATION | 1 | 1 1.0|
ECTOPIC THYMUS | | 1 |
HYPERPLASIA,FOLLICULAR CELL | 2 | 1 2.0|
HYPERTROPHY,FOLLICULAR CELL | 2 | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 2 1.5|
ULTIMOBRANCHIAL CYST | 2 2 3 | 7 2.1|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + M + + + + + + + + + + + + M | 33 |
ATROPHY | 3 3 3 3 3 3 4 3 3 3 4 3 | 31 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
OVARY | + + + + + + + + + + + + + + + | 38 |
ANGIECTASIS | 2 | 1 2.0|
ATROPHY | X X X X X X X X X X X X X | 32 |
CYST | X X X X X X | 9 |
CYST,PERIOVARIAN TISSUE | X X | 8 |
HEMATOCYST | X X X | 4 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
MINERALIZATION | 2 | 1 2.0|
UTERUS | + + + + + + + + + + + + + + + | 39 |
ATROPHY | | 1 3.0|
DILATATION | 3 | 1 3.0|
ECTASIA,VEIN | 2 | 1 2.0|
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 3 2 2 2 3 2 3 2 2 2 2 2 | 29 2.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 1 2.0|
INFLAMMATION | | 1 2.0|
VAGINA | + + + + + + + + + + + + + + + | 37 |
METAPLASIA | 4 | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 89
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:49.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 7| 7| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| S R R|
| 1| 1| 1| 8| 8| 8| 8| 8| 9| 4| 4| 4| 5| 5| 5| U V I|
100MG F12MTH 10 10 | 2| 3| 4| 5| 6| 7| 8| 9| 0| 7| 8| 9| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + | 38 |
HYPERPLASIA | | 3 3.0|
LYMPH NODE | + + + + + + + + + + + + + + + | 40 |
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + | 39 |
HYPERPLASIA,LYMPHOID | 2 2 3 | 4 2.2|
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + + + + | 39 |
ATROPHY | 2 | 1 2.0|
CONGESTION,SINUS | 2 | 1 2.0|
HEMORRHAGE | | 1 2.0|
HYPERPLASIA,LYMPHOID | 2 2 | 4 2.2|
SPLEEN | + + + + + + + + + + + + + + + | 39 |
ATROPHY | | 1 2.0|
CONGESTION | 2 | 3 1.6|
ERYTHROPHAGOCYTOSIS | | 1 1.0|
HEMATOPOIETIC CELL PROLIFERATION | 3 3 | 4 3.5|
HYPERPLASIA,LYMPHOID | 1 1 2 3 | 12 1.6|
THYMUS | + M + + + + + M M + + + M + + | 30 |
ATROPHY,CORTEX | 4 3 3 3 2 1 3 3 3 | 25 2.9|
CONGESTION | | 1 2.0|
ECTOPIC PARATHYROID GLAND | | 1 |
HYPERPLASIA,LYMPHOID,MEDULLA | 2 3 1 3 | 6 2.1|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + M + + + + + + + + + + | 36 |
HYPERPLASIA | 2 3 | 3 2.3|
SKIN | + + + + + + + + + + + + + + + | 38 |
ALOPECIA | | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + | 40 |
BONE,FEMUR | + + + + + + + + + + + + + + + | 40 |
DEGENERATION,CARTILAGE | 4 | 1 4.0|
FIBROUS OSTEODYSTROPHY | 1 1 2 2 | 9 1.7|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 90
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:49.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 7| 7| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| S R R|
| 1| 1| 1| 8| 8| 8| 8| 8| 9| 4| 4| 4| 5| 5| 5| U V I|
100MG F12MTH 10 10 | 2| 3| 4| 5| 6| 7| 8| 9| 0| 7| 8| 9| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
BONE,STERNUM | + + + + + + + + + + + + + + + | 40 |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 2 1 2 3 1 2 3 1 2 2 3 2 | 29 2.1|
SKELETAL MUSCLE | + + + + + + + + + + + + + + + | 39 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + | 40 |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + | 40 |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + | 40 |
MINERALIZATION,MULTIFOCAL,THALAMUS | 2 1 1 1 1 1 1 1 1 1 | 24 1.0|
PERIPHERAL NERVE | + + + + + + + + + + + + + + + | 38 |
SPINAL CORD | + + + + + + + + + + + + + + + | 39 |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + | 39 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + + + M + + + + + + + + | 34 |
CONCRETION | 2 | 1 2.0|
CRYSTALS | 1 | 1 1.0|
LUNG | + + + + + + + + + + + + + + + | 40 |
CONGESTION | | 1 4.0|
GIANT CELL | 2 | 1 2.0|
HEMORRHAGE | 2 2 | 2 2.0|
HYPERPLASIA,ALVEOLAR EPITHELIUM | | 2 1.0|
INFILTRATION CELLULAR,HISTIOCYTIC | 1 | 2 1.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 2 1 1 2 2 2 2 | 27 1.1|
INFLAMMATION | 1 1 1 | 3 1.0|
THROMBUS,CAPILLARY | | 1 4.0|
NOSE | + + + + + + + + + + + + + + + | 40 |
TRACHEA | + + + + + + + + + + + + + + + | 39 |
CYST | | 1 2.0|
FOREIGN BODY | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 91
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:36:49.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 7| 7| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| S R R|
| 1| 1| 1| 8| 8| 8| 8| 8| 9| 4| 4| 4| 5| 5| 5| U V I|
100MG F12MTH 10 10 | 2| 3| 4| 5| 6| 7| 8| 9| 0| 7| 8| 9| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + + + + + + + + | 35 |
HARDERIAN GLAND | + + + + + + + + + + + + + + + | 38 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 | 8 1.0|
INFLAMMATION | 4 | 1 4.0|
LACRIMAL GLAND | M M + + + + M + + M + + + + + | 32 |
ATROPHY | 2 | 2 2.0|
CYTOMEGALY | 2 | 1 2.0|
ECTASIA,DUCT | 2 | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 3 1 2 | 13 1.2|
ZYMBAL'S GLAND | + + + M + + + + + + + + + + + | 36 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + | 38 |
AMYLOID DEPOSITION,GLOMERULUS | 2 | 2 2.5|
CYST,RENAL TUBULE | 1 3 | 8 1.2|
GLOMERULOSCLEROSIS | | 1 3.0|
HYDRONEPHROSIS | | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 2 | 32 1.1|
NEPHROPATHY | 1 2 1 | 4 1.2|
PIGMENTATION,RENAL TUBULE | | 1 1.0|
URINARY BLADDER | + + + + + + + + + + + + + + + | 36 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 2 2 1 1 1 | 28 1.1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 92
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:04.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 8| 6| 9| 6| 1| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 9| 1| 1| 8| 7| 3| 5| 5| 5| 5| 6| 6| 6| 6| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 2| 2| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| S R R|
| 8| 9| 7| 8| 0| 2| 9| 9| 9| 9| 3| 3| 3| 3| 4| 4| 4| 7| 7| 7| 6| 6| 6| 6| 6| U V I|
CONTRL FS-2YR 11 11 | 3| 3| 7| 7| 8| 9| 5| 6| 7| 8| 1| 2| 3| 4| 0| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
GALLBLADDER | + A A + + + + + + + + + + + + + M + + + + M + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | |
INTESTINE LARGE | + A A + + + + + + + + + + + + + + + + + + + + + + | |
INTESTINE LARGE,CECUM | + A A + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | 2 | |
INTESTINE LARGE,COLON | + A A + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,GOBLET CELL | 3 | |
INTESTINE LARGE,RECTUM | + A A + + + + + + + + + + + + + + + + + + + + + + | |
FIBROSIS | 3 | |
INTESTINE SMALL | + A A + + A + + + + + + + + + + + + + + + + + + + | |
INTESTINE SMALL,DUODENUM | + A A + + A + + + + + + + + + + + + + + + + + + + | |
INTESTINE SMALL,ILEUM | + A A + + A + + + + + + + + + + + + M + + + + + + | |
ATROPHY | 2 | |
INTESTINE SMALL,JEJUNUM | + A A + + A + + + + + + + + + + + + M + + + + + + | |
HYPERPLASIA,LYMPHOID | | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BASOPHILIC FOCUS | | |
HEMATOPOIETIC CELL PROLIFERATION | 2 1 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 2 1 1 1 2 1 2 1 3 2 1 1 1 1 1 1 1 1 1| |
INFLAMMATION | 1 | |
NECROSIS | 1 1 1 1 1 1 1 1| |
NECROSIS,COAGULATIVE | 1 | |
TENSION LIPOIDOSIS | X X X X X X X X | |
VACUOLIZATION CYTOPLASMIC | 1 1 1 1 1 1 1 1 2 1| |
MESENTERY | + | |
NECROSIS,FAT | 4 | |
PANCREAS | + A A + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 1 1| |
DEGENERATION | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 1| |
INFLAMMATION | 2 | |
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 1 2 1 1 2 2 1 1 2 2 1 2 1 2 2 2 1| |
STOMACH | + A + + + + + + + + + + + + + + + + + + + + + + + | |
STOMACH,FORESTOMACH | + A + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 93
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:04.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 8| 6| 9| 6| 1| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 9| 1| 1| 8| 7| 3| 5| 5| 5| 5| 6| 6| 6| 6| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 2| 2| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| S R R|
| 8| 9| 7| 8| 0| 2| 9| 9| 9| 9| 3| 3| 3| 3| 4| 4| 4| 7| 7| 7| 6| 6| 6| 6| 6| U V I|
CONTRL FS-2YR 11 11 | 3| 3| 7| 7| 8| 9| 5| 6| 7| 8| 1| 2| 3| 4| 0| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
HYPERKERATOSIS | | |
STOMACH,GLANDULAR | + A + + + + + + + + + + + + + + + + + + + + + + + | |
CYST | 2 1 | |
HYPERPLASIA | 2 | |
MINERALIZATION | 1 | |
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,MAST CELL | | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | M + + + + + + + + + + + + + + + + + + + + + + + + | |
BLOOD VESSEL,AORTA | M + + + + + + + + + + + + + + + + + + + + + + + + | |
HEART | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CARDIOMYOPATHY | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
THROMBUS | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + A + + + + + + + + + + + + + + + + + + + + + + + | |
ACCESSORY ADRENAL CORTICAL NODULE | | |
ADRENAL GLAND,CORTEX | + A + + + + + + + + + + + + + + + + + + + + + + + | |
HEMATOPOIETIC CELL PROLIFERATION | | |
HYPERPLASIA,SPINDLE CELL | 2 1 3 2 2 3 3 3 2 2 3 2 2 2 2 2 2 2 1 2 1 2 2| |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
VACUOLIZATION CYTOPLASMIC | 2 | |
ADRENAL GLAND,MEDULLA | + A + + + + + + + + + + + + + + + + + + + + + + + | |
INFLAMMATION | 3 | |
VACUOLIZATION CYTOPLASMIC | | |
ISLETS, PANCREATIC | + A A + + + + + + + + + + + + + + + + + + + + + + | |
PARATHYROID GLAND | M + + + M + + + + + + + + + + + + M M + M + + + M | |
CYST | 2 | |
ECTOPIC THYMUS | X X | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 | |
PITUITARY GLAND | M + + + M + M + + + + + + + + + M + + + + + + + + | |
CYTOMEGALY | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 94
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:05.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 8| 6| 9| 6| 1| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 9| 1| 1| 8| 7| 3| 5| 5| 5| 5| 6| 6| 6| 6| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 2| 2| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| S R R|
| 8| 9| 7| 8| 0| 2| 9| 9| 9| 9| 3| 3| 3| 3| 4| 4| 4| 7| 7| 7| 6| 6| 6| 6| 6| U V I|
CONTRL FS-2YR 11 11 | 3| 3| 7| 7| 8| 9| 5| 6| 7| 8| 1| 2| 3| 4| 0| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
DEGENERATION,CYSTIC,PARS DISTALIS | | |
HYPERPLASIA,PARS DISTALIS | 2 2 | |
HYPERTROPHY,PARS DISTALIS | 1 2 | |
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CYST,FOLLICLE | | |
ECTOPIC THYMUS | X | |
HYPERPLASIA,FOLLICULAR CELL | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
INFLAMMATION | | |
ULTIMOBRANCHIAL CYST | 3 3 2 2 2 2 2 2 | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + + M M + + + + + + M + M + + + + + + + + M M + | |
ATROPHY | 4 3 3 4 3 2 3 3 3 3 4 3 4 4 3 4 4 4| |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
INFLAMMATION | | |
OVARY | + A + + + + + + + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | | |
ATROPHY | X X X X X X X X X X X X X X X X X X X | |
CONGESTION | 2 | |
CYST | X X X X X X | |
CYST,PERIOVARIAN TISSUE | X X X X X X | |
HEMATOCYST | X | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
UTERUS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | 2 | |
ATROPHY | 3 4 | |
DILATATION | 4 4 | |
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 2 2 2 4 3 2 2 2 1 2 1 2 2 3 2 2 2 2| |
INFLAMMATION | 2 | |
VAGINA | + + A + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 4 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 95
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:05.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 8| 6| 9| 6| 1| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 9| 1| 1| 8| 7| 3| 5| 5| 5| 5| 6| 6| 6| 6| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 2| 2| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| S R R|
| 8| 9| 7| 8| 0| 2| 9| 9| 9| 9| 3| 3| 3| 3| 4| 4| 4| 7| 7| 7| 6| 6| 6| 6| 6| U V I|
CONTRL FS-2YR 11 11 | 3| 3| 7| 7| 8| 9| 5| 6| 7| 8| 1| 2| 3| 4| 0| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | 3 2 | |
MYELOFIBROSIS | 4 | |
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID,BRONCHIAL | | |
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HEMORRHAGE | 2 | |
HYPERPLASIA,LYMPHOID | 2 3 2 3 1 | |
LYMPH NODE,MESENTERIC | + + + + M + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 | |
HEMATOPOIETIC CELL PROLIFERATION | | |
HEMORRHAGE | 2 | |
HYPERPLASIA,LYMPHOID | | |
HYPERPLASIA,RETICULUM CELL | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
SPLEEN | + A + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 | |
CONGESTION | 2 | |
HEMATOPOIETIC CELL PROLIFERATION | 3 3 | |
HYPERPLASIA,LYMPHOID | 1 2 1 2 3 4 3 1| |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
THYMUS | M + M + M M + M M + + + + + + M + + + + + + + + + | |
ATROPHY,CORTEX | 4 3 3 3 3 2 3 3 3 2 4 4 3 2| |
CYST | | |
ECTOPIC PARATHYROID GLAND | X | |
HYPERPLASIA,LYMPHOID,MEDULLA | 2 4 2 3 2 1 3| |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + M + M + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
LACTATION | | |
SKIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 96
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:05.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 8| 6| 9| 6| 1| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 9| 1| 1| 8| 7| 3| 5| 5| 5| 5| 6| 6| 6| 6| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 2| 2| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| S R R|
| 8| 9| 7| 8| 0| 2| 9| 9| 9| 9| 3| 3| 3| 3| 4| 4| 4| 7| 7| 7| 6| 6| 6| 6| 6| U V I|
CONTRL FS-2YR 11 11 | 3| 3| 7| 7| 8| 9| 5| 6| 7| 8| 1| 2| 3| 4| 0| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY | 1 1 1 3 1 1 2 | |
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 2 3 1 1 3 2 3 3 1 1 3 2 1 2 2 2 2 | |
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
MINERALIZATION,THALAMUS | | |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DEVELOPMENTAL MALFORMATION | X | |
GLIOSIS | | |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 1 1 1 1 2 2 1 1 2 1 1 1 1| |
NECROSIS | | |
PERIPHERAL NERVE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + + + | |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + M M M + + + + + + + + M + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CONGESTION | 3 | |
HYPERPLASIA,ALVEOLAR EPITHELIUM | 2 2 | |
INFILTRATION CELLULAR,HISTIOCYTIC | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 1 1| |
NOSE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
TRACHEA | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 97
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:05.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 8| 6| 9| 6| 1| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 9| 1| 1| 8| 7| 3| 5| 5| 5| 5| 6| 6| 6| 6| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 2| 2| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| S R R|
| 8| 9| 7| 8| 0| 2| 9| 9| 9| 9| 3| 3| 3| 3| 4| 4| 4| 7| 7| 7| 6| 6| 6| 6| 6| U V I|
CONTRL FS-2YR 11 11 | 3| 3| 7| 7| 8| 9| 5| 6| 7| 8| 1| 2| 3| 4| 0| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
EYE | + A A + + A + + + + + + + + + + + + + + + + + + + | |
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 | |
LACRIMAL GLAND | + + + + M M + + + + + M M + + + + + + + + + + + + | |
ATROPHY | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 1 1 1 2 1 1 2 2 1| |
ZYMBAL'S GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 | |
HYPERPLASIA,SQUAMOUS | | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AMYLOID DEPOSITION,GLOMERULUS | | |
CYST,RENAL TUBULE | 1 1 1 1 1 | |
GLOMERULOSCLEROSIS | 3 | |
HYDRONEPHROSIS | 2 2 | |
HYPERPLASIA,RENAL TUBULE | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 2 1 1 1 2 2 1 1 1 1 1 1 1 1 1| |
MINERALIZATION | 2 | |
NECROSIS,RENAL TUBULE | 3 | |
NEPHROPATHY | 1 1 1 | |
VACUOLIZATION CYTOPLASMIC,RENAL TUBULE | 1 | |
URINARY BLADDER | + + M + + + + + + + + + + + + + + + + + + + + + + | |
FIBROSIS,ADVENTITIA | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 1 1 1| |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 98
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:19.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| S R R|
| 6| 4| 4| 4| 5| 6| 6| 7| 1| 1| 1| 1| 2| 2| 2| 2| 9| 9| 9| 9| 9| 0| 0| U V I|
CONTRL FS-2YR 11 11 | 6| 7| 8| 9| 0| 8| 9| 0| 6| 7| 8| 9| 4| 5| 6| 7| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + M + + + + + + + + M + M + + + + | 45 |
GALLBLADDER | + + + + + + M + + + + + + + + + + + + + + + + | 43 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 3 1.0|
INTESTINE LARGE | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
INTESTINE LARGE,CECUM | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
HYPERPLASIA,LYMPHOID | 3 3 2 2 3 | 6 2.5|
INTESTINE LARGE,COLON | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
HYPERPLASIA,GOBLET CELL | | 1 3.0|
INTESTINE LARGE,RECTUM | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
FIBROSIS | | 1 3.0|
INTESTINE SMALL | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
INTESTINE SMALL,DUODENUM | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
INTESTINE SMALL,ILEUM | + + + + + + + + + + + + M + + + + + + + + M + | 42 |
ATROPHY | | 1 2.0|
INTESTINE SMALL,JEJUNUM | + + + + + + + + + + + + + + + + + + + + + + + | 44 |
HYPERPLASIA,LYMPHOID | 2 | 1 2.0|
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BASOPHILIC FOCUS | X | 1 |
HEMATOPOIETIC CELL PROLIFERATION | 1 | 5 1.2|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 2 | 42 1.2|
INFLAMMATION | | 1 1.0|
NECROSIS | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 | 27 1.0|
NECROSIS,COAGULATIVE | 3 | 2 2.0|
TENSION LIPOIDOSIS | X X X X X X X X X X X | 19 |
VACUOLIZATION CYTOPLASMIC | 1 1 1 1 1 2 2 2 1 1 2 2 1 2 1 2 1 1 1 1 1 | 31 1.2|
MESENTERY | + | 2 |
NECROSIS,FAT | 4 | 2 4.0|
PANCREAS | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
ATROPHY | | 2 1.0|
DEGENERATION | 1 | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 2 1 1 1 1 1 1 2 | 24 1.0|
INFLAMMATION | | 1 2.0|
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 2 1 1 1 1 1 2 1 2 1 2 1 2 1 2 1 2 2 1 | 41 1.4|
STOMACH | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
STOMACH,FORESTOMACH | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 99
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:19.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| S R R|
| 6| 4| 4| 4| 5| 6| 6| 7| 1| 1| 1| 1| 2| 2| 2| 2| 9| 9| 9| 9| 9| 0| 0| U V I|
CONTRL FS-2YR 11 11 | 6| 7| 8| 9| 0| 8| 9| 0| 6| 7| 8| 9| 4| 5| 6| 7| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
HYPERKERATOSIS | 2 | 1 2.0|
STOMACH,GLANDULAR | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
CYST | 2 2 1 | 5 1.6|
HYPERPLASIA | 1 | 2 1.5|
MINERALIZATION | | 1 1.0|
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,MAST CELL | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + M + + + + + + + + + + + + + + + + | 46 |
BLOOD VESSEL,AORTA | + + + + + + M + + + + + + + + + + + + + + + + | 46 |
HEART | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
CARDIOMYOPATHY | 1 | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
THROMBUS | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | M + + + + + + + + + + + + + + + + + + + + + + | 46 |
ACCESSORY ADRENAL CORTICAL NODULE | X | 1 |
ADRENAL GLAND,CORTEX | M + + + + + + + + + + + + + + + + + + + + + + | 46 |
HEMATOPOIETIC CELL PROLIFERATION | 1 | 1 1.0|
HYPERPLASIA,SPINDLE CELL | 2 2 2 3 2 2 1 3 2 2 3 1 2 1 2 2 3 1 2 2 1 | 44 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 1 2.0|
VACUOLIZATION CYTOPLASMIC | | 1 2.0|
ADRENAL GLAND,MEDULLA | M + + + + + + + + + + + + + + + + + + + + + + | 46 |
INFLAMMATION | | 1 3.0|
VACUOLIZATION CYTOPLASMIC | 2 | 1 2.0|
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
PARATHYROID GLAND | + + + + M + + + + M + M + + + M + + + + + + + | 38 |
CYST | | 1 2.0|
ECTOPIC THYMUS | | 2 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 3.0|
PITUITARY GLAND | + + + + + M M M + + + + + + M + + + + + + + + | 40 |
CYTOMEGALY | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 100
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:19.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| S R R|
| 6| 4| 4| 4| 5| 6| 6| 7| 1| 1| 1| 1| 2| 2| 2| 2| 9| 9| 9| 9| 9| 0| 0| U V I|
CONTRL FS-2YR 11 11 | 6| 7| 8| 9| 0| 8| 9| 0| 6| 7| 8| 9| 4| 5| 6| 7| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
DEGENERATION,CYSTIC,PARS DISTALIS | 2 | 1 2.0|
HYPERPLASIA,PARS DISTALIS | 2 | 3 2.0|
HYPERTROPHY,PARS DISTALIS | | 2 1.5|
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
CYST,FOLLICLE | 2 | 1 2.0|
ECTOPIC THYMUS | | 1 |
HYPERPLASIA,FOLLICULAR CELL | 2 | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 2 1.0|
INFLAMMATION | 1 | 1 1.0|
ULTIMOBRANCHIAL CYST | 2 2 2 3 2 2 2 3 2 4 2 | 19 2.3|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + + + M + + M + + + + + + + + + + + + M + M | 38 |
ATROPHY | 3 4 3 4 4 4 3 4 3 3 4 2 3 4 3 3 3 3 4 | 37 3.3|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 2.0|
INFLAMMATION | 1 | 1 1.0|
OVARY | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ANGIECTASIS | 2 | 1 2.0|
ATROPHY | X X X X X X X X X X X X X X X X X X | 37 |
CONGESTION | | 1 2.0|
CYST | X X X | 9 |
CYST,PERIOVARIAN TISSUE | X X X X | 10 |
HEMATOCYST | X X X | 4 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 2 2.0|
UTERUS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ANGIECTASIS | | 1 2.0|
ATROPHY | | 2 3.5|
DILATATION | 3 3 | 4 3.5|
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 1 2 2 2 2 2 3 2 3 2 2 2 1 2 3 3 3 3 2 3 2 | 40 2.1|
INFLAMMATION | | 1 2.0|
VAGINA | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ATROPHY | 2 | 2 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 101
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:19.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| S R R|
| 6| 4| 4| 4| 5| 6| 6| 7| 1| 1| 1| 1| 2| 2| 2| 2| 9| 9| 9| 9| 9| 0| 0| U V I|
CONTRL FS-2YR 11 11 | 6| 7| 8| 9| 0| 8| 9| 0| 6| 7| 8| 9| 4| 5| 6| 7| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HYPERPLASIA | 3 | 3 2.6|
MYELOFIBROSIS | | 1 4.0|
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HYPERPLASIA,LYMPHOID,BRONCHIAL | 2 | 1 2.0|
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HEMORRHAGE | | 1 2.0|
HYPERPLASIA,LYMPHOID | 3 3 2 | 8 2.3|
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ATROPHY | | 1 3.0|
HEMATOPOIETIC CELL PROLIFERATION | 1 | 1 1.0|
HEMORRHAGE | 2 | 2 2.0|
HYPERPLASIA,LYMPHOID | 2 2 | 2 2.0|
HYPERPLASIA,RETICULUM CELL | 3 | 1 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 | 1 3.0|
SPLEEN | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ATROPHY | | 1 3.0|
CONGESTION | 1 1 | 3 1.3|
HEMATOPOIETIC CELL PROLIFERATION | 3 4 | 4 3.2|
HYPERPLASIA,LYMPHOID | 4 3 3 2 2 2 2 1 1 3 2 3 2 | 21 2.2|
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 | 1 3.0|
THYMUS | + + M + + + + + + + + + M + + + + + + + + + M | 38 |
ATROPHY,CORTEX | 3 2 2 2 2 4 3 3 4 2 2 2 3 | 27 2.8|
CYST | 2 | 1 2.0|
ECTOPIC PARATHYROID GLAND | | 1 |
HYPERPLASIA,LYMPHOID,MEDULLA | 3 2 2 3 1 3 1 2 1 | 16 2.1|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
HYPERPLASIA | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
LACTATION | 1 | 1 1.0|
SKIN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 102
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:19.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| S R R|
| 6| 4| 4| 4| 5| 6| 6| 7| 1| 1| 1| 1| 2| 2| 2| 2| 9| 9| 9| 9| 9| 0| 0| U V I|
CONTRL FS-2YR 11 11 | 6| 7| 8| 9| 0| 8| 9| 0| 6| 7| 8| 9| 4| 5| 6| 7| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
FIBROUS OSTEODYSTROPHY | 1 2 1 1 2 1 | 13 1.3|
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 1 2 2 2 2 3 2 1 2 3 3 1 2 3 2 2 3 2 1 | 36 2.0|
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 2 1.5|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
MINERALIZATION,THALAMUS | 1 | 1 1.0|
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
DEVELOPMENTAL MALFORMATION | | 1 |
GLIOSIS | 2 | 1 2.0|
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 1 1 1 1 1 2 1 1 1 1 2 1 1 1 | 31 1.1|
NECROSIS | 2 | 1 2.0|
PERIPHERAL NERVE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + + + + + + + + + + + + + + + + + + + + | 44 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
LUNG | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
CONGESTION | | 1 3.0|
HYPERPLASIA,ALVEOLAR EPITHELIUM | | 2 2.0|
INFILTRATION CELLULAR,HISTIOCYTIC | 1 | 2 1.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 1 1 2 2 2 1 1 1 2 1 2 2 2 2 2 | 40 1.3|
NOSE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
TRACHEA | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 103
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:19.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| S R R|
| 6| 4| 4| 4| 5| 6| 6| 7| 1| 1| 1| 1| 2| 2| 2| 2| 9| 9| 9| 9| 9| 0| 0| U V I|
CONTRL FS-2YR 11 11 | 6| 7| 8| 9| 0| 8| 9| 0| 6| 7| 8| 9| 4| 5| 6| 7| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 2 | 14 1.0|
LACRIMAL GLAND | M + + + + + + + + + + + + + + M + + + M + + + | 41 |
ATROPHY | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 2 2 1 1 2 1 1 | 25 1.2|
ZYMBAL'S GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY | | 1 3.0|
HYPERPLASIA,SQUAMOUS | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AMYLOID DEPOSITION,GLOMERULUS | 4 4 | 2 4.0|
CYST,RENAL TUBULE | 1 1 1 1 1 | 10 1.0|
GLOMERULOSCLEROSIS | 2 | 2 2.5|
HYDRONEPHROSIS | | 2 2.0|
HYPERPLASIA,RENAL TUBULE | 1 | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 2 2 1 1 2 1 1 1 1 1 1 1 1 1 1 2 2 1 | 42 1.2|
MINERALIZATION | | 1 2.0|
NECROSIS,RENAL TUBULE | | 1 3.0|
NEPHROPATHY | 1 2 1 1 | 7 1.1|
VACUOLIZATION CYTOPLASMIC,RENAL TUBULE | | 1 1.0|
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
FIBROSIS,ADVENTITIA | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 2 1 1 1 1 2 2 2 1 1 1 1 2 2 1 1 | 41 1.2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 104
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:24.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 6| 7| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 6| 6| 9| 0| 8| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 3| 8| 5| 8| 8| 2| 7| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 1| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| S R R|
| 6| 8| 8| 9| 0| 8| 8| 7| 7| 7| 7| 7| 7| 7| 7| 3| 3| 3| 3| 7| 7| 7| 5| 5| 5| U V I|
10MG FS-2YR 12 12 | 9| 5| 6| 6| 0| 3| 7| 1| 2| 3| 4| 5| 6| 7| 8| 6| 7| 8| 9| 0| 1| 2| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + | |
HYPERKERATOSIS | 2 | |
GALLBLADDER | + + + + + + + | |
INTESTINE LARGE | A + + + + + + | |
INTESTINE LARGE,CECUM | A + A + + + + | |
HYPERPLASIA,LYMPHOID | 2 | |
INTESTINE LARGE,COLON | A + + + + + + | |
INTESTINE LARGE,RECTUM | A + + + + + + | |
INTESTINE SMALL | A + A + + + + + + | |
INTESTINE SMALL,DUODENUM | A + A + + + + + | |
INTESTINE SMALL,ILEUM | A + A + + + + | |
HYPERPLASIA,LYMPHOID | 2 | |
INTESTINE SMALL,JEJUNUM | A + A + + + + + | |
HYPERPLASIA,LYMPHOID | 2 | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BASOPHILIC FOCUS | | |
CYST,BILE DUCT | | |
DEGENERATION | 1 | |
DEGENERATION,FATTY | 2 | |
EOSINOPHILIC FOCUS | X | |
HEMATOPOIETIC CELL PROLIFERATION | 2 1 2 1 1 1 3| |
HYPERPLASIA,KUPFFER CELL | 3 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 1 1 1 2 1 1 2 1 1 1 1 1 | |
INFILTRATION CELLULAR,PLASMA CELL | 1 | |
NECROSIS | 1 1 2 1 1 1 2 1 2 1 1 1 1 1 | |
NECROSIS,COAGULATIVE | 1 | |
REGENERATION | 2 | |
TENSION LIPOIDOSIS | X X X X X X X | |
VACUOLIZATION CYTOPLASMIC | 1 2 1 1 2 2 1 2 2 2 2 2 1 2 1 1 1 1| |
MESENTERY | + + + + | |
NECROSIS,FAT | 4 4 4 | |
PANCREAS | A + + + + + + + | |
CYST,DUCT | 4 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 | |
SALIVARY GLANDS | + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 2 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 105
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:24.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 6| 7| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 6| 6| 9| 0| 8| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 3| 8| 5| 8| 8| 2| 7| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 1| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| S R R|
| 6| 8| 8| 9| 0| 8| 8| 7| 7| 7| 7| 7| 7| 7| 7| 3| 3| 3| 3| 7| 7| 7| 5| 5| 5| U V I|
10MG FS-2YR 12 12 | 9| 5| 6| 6| 0| 3| 7| 1| 2| 3| 4| 5| 6| 7| 8| 6| 7| 8| 9| 0| 1| 2| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
STOMACH | A + + + + + + | |
STOMACH,FORESTOMACH | A + + + + + + | |
STOMACH,GLANDULAR | A + + + + + + | |
CYST | 1 | |
TONGUE | + + + + + + + | |
MINERALIZATION | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + M + + + + + | |
BLOOD VESSEL,AORTA | + M + + + + + | |
HEART | + + + + + + + | |
HYPERPLASIA,EPICARDIUM | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + | |
ADRENAL GLAND,CORTEX | + + + + + + + | |
HYPERPLASIA,SPINDLE CELL | 2 2 2 1 | |
ADRENAL GLAND,MEDULLA | + + + + + + + | |
ISLETS, PANCREATIC | A + + + + + + | |
PARATHYROID GLAND | + + + + + + + | |
PITUITARY GLAND | A + + + M + M | |
THYROID GLAND | + + + + + + + | |
ULTIMOBRANCHIAL CYST | 3 2 | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + + + + + + | |
ATROPHY | 3 3 3 3 2 2 4 | |
OVARY | + + + + + + + + + + + + + + | |
ATROPHY | X X X X X | |
CYST | X X X X X | |
CYST,PERIOVARIAN TISSUE | X X | |
UTERUS | + + + + + + + + + + + + + + + | |
ATROPHY | 3 4 4 2 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 106
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:24.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 6| 7| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 6| 6| 9| 0| 8| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 3| 8| 5| 8| 8| 2| 7| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 1| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| S R R|
| 6| 8| 8| 9| 0| 8| 8| 7| 7| 7| 7| 7| 7| 7| 7| 3| 3| 3| 3| 7| 7| 7| 5| 5| 5| U V I|
10MG FS-2YR 12 12 | 9| 5| 6| 6| 0| 3| 7| 1| 2| 3| 4| 5| 6| 7| 8| 6| 7| 8| 9| 0| 1| 2| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
DILATATION | | |
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 1 3 2 1 3 3 4 2| |
VAGINA | + + + + + + + | |
ATROPHY | 3 3 4 4 | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + | |
DEPLETION | 2 | |
HYPERPLASIA | 3 | |
MYELOFIBROSIS | 2 | |
LYMPH NODE | + + + + + + + + + | |
HYPERPLASIA,LYMPHOID,INGUINAL | | |
LYMPH NODE,MANDIBULAR | + + + + + + + | |
HEMATOPOIETIC CELL PROLIFERATION | 3 | |
LYMPH NODE,MESENTERIC | + + + + M + + + | |
ATROPHY | 2 4 | |
HEMATOPOIETIC CELL PROLIFERATION | 3 | |
HEMORRHAGE | 3 | |
SPLEEN | + + + + + + + + + + + + + + | |
ATROPHY | 3 3 | |
CONGESTION | 1 | |
HEMATOPOIETIC CELL PROLIFERATION | 3 2 4 | |
HYPERPLASIA,LYMPHOID | 1 2 | |
THYMUS | + + + M M + + | |
ATROPHY,CORTEX | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | A + + M + + + | |
HYPERPLASIA | 3 | |
SKIN | A + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 107
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:24.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 6| 7| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 6| 6| 9| 0| 8| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 3| 8| 5| 8| 8| 2| 7| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 1| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| S R R|
| 6| 8| 8| 9| 0| 8| 8| 7| 7| 7| 7| 7| 7| 7| 7| 3| 3| 3| 3| 7| 7| 7| 5| 5| 5| U V I|
10MG FS-2YR 12 12 | 9| 5| 6| 6| 0| 3| 7| 1| 2| 3| 4| 5| 6| 7| 8| 6| 7| 8| 9| 0| 1| 2| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + | |
BONE,FEMUR | + + + + + + + | |
BONE,STERNUM | + + + + + + + | |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 2 2 | |
SKELETAL MUSCLE | + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + | |
BRAIN,CEREBRUM | + + + + + + + | |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 1 1 | |
PERIPHERAL NERVE | + + + + + + + | |
SPINAL CORD | + + + + + + + | |
SPINAL CORD,THORACIC | + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + M M + M M + | |
LUNG | + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 | |
NOSE | + + + + + + + | |
TRACHEA | + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | A + A A + + + | |
HARDERIAN GLAND | + + + + + + + + | |
HYPERPLASIA | 4 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
LACRIMAL GLAND | + M M M + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 | |
ZYMBAL'S GLAND | M + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 108
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:24.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 6| 7| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 6| 6| 9| 0| 8| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 3| 8| 5| 8| 8| 2| 7| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 1| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| S R R|
| 6| 8| 8| 9| 0| 8| 8| 7| 7| 7| 7| 7| 7| 7| 7| 3| 3| 3| 3| 7| 7| 7| 5| 5| 5| U V I|
10MG FS-2YR 12 12 | 9| 5| 6| 6| 0| 3| 7| 1| 2| 3| 4| 5| 6| 7| 8| 6| 7| 8| 9| 0| 1| 2| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM
KIDNEY | + + + + + + + | |
ACCUMULATION HYALINE DROPLET | 4 | |
CYST,RENAL TUBULE | 1 | |
GLOMERULOSCLEROSIS | 3 3 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 2 | |
URETER | | |
URINARY BLADDER | + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 109
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:26.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 1| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| S R R|
| 5| 5| 5| 6| 4| 4| 4| 6| 6| 5| 5| 5| 5| 5| 5| 8| 8| 8| 9| 9| 9| 9| 9| U V I|
10MG FS-2YR 12 12 | 7| 8| 9| 0| 4| 5| 6| 6| 7| 3| 4| 5| 6| 7| 8| 0| 8| 9| 0| 1| 2| 3| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | M | 7 |
HYPERKERATOSIS | | 1 2.0|
GALLBLADDER | + | 8 |
INTESTINE LARGE | + | 7 |
INTESTINE LARGE,CECUM | + | 6 |
HYPERPLASIA,LYMPHOID | | 1 2.0|
INTESTINE LARGE,COLON | + | 7 |
INTESTINE LARGE,RECTUM | + | 7 |
INTESTINE SMALL | + | 8 |
INTESTINE SMALL,DUODENUM | + | 7 |
INTESTINE SMALL,ILEUM | + | 6 |
HYPERPLASIA,LYMPHOID | | 1 2.0|
INTESTINE SMALL,JEJUNUM | + | 7 |
HYPERPLASIA,LYMPHOID | | 1 2.0|
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BASOPHILIC FOCUS | X | 1 |
CYST,BILE DUCT | 2 | 1 2.0|
DEGENERATION | | 1 1.0|
DEGENERATION,FATTY | | 1 2.0|
EOSINOPHILIC FOCUS | X | 2 |
HEMATOPOIETIC CELL PROLIFERATION | 1 1 1 1 1 1 | 13 1.3|
HYPERPLASIA,KUPFFER CELL | | 2 2.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 2 1 | 35 1.1|
INFILTRATION CELLULAR,PLASMA CELL | | 1 1.0|
NECROSIS | 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 | 33 1.1|
NECROSIS,COAGULATIVE | | 1 1.0|
REGENERATION | | 1 2.0|
TENSION LIPOIDOSIS | X X X X X X X | 14 |
VACUOLIZATION CYTOPLASMIC | 2 1 1 2 1 2 2 2 2 2 1 1 1 2 2 2 2 1 | 36 1.5|
MESENTERY | | 4 |
NECROSIS,FAT | | 3 4.0|
PANCREAS | + | 8 |
CYST,DUCT | | 1 4.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 5 1.0|
SALIVARY GLANDS | + + | 9 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 5 1.4|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 110
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:26.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 1| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| S R R|
| 5| 5| 5| 6| 4| 4| 4| 6| 6| 5| 5| 5| 5| 5| 5| 8| 8| 8| 9| 9| 9| 9| 9| U V I|
10MG FS-2YR 12 12 | 7| 8| 9| 0| 4| 5| 6| 6| 7| 3| 4| 5| 6| 7| 8| 0| 8| 9| 0| 1| 2| 3| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
STOMACH | + | 7 |
STOMACH,FORESTOMACH | + | 7 |
STOMACH,GLANDULAR | + | 7 |
CYST | | 1 1.0|
TONGUE | + | 8 |
MINERALIZATION | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + | 7 |
BLOOD VESSEL,AORTA | + | 7 |
HEART | + | 8 |
HYPERPLASIA,EPICARDIUM | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + | 9 |
ADRENAL GLAND,CORTEX | + | 8 |
HYPERPLASIA,SPINDLE CELL | | 4 1.7|
ADRENAL GLAND,MEDULLA | + | 8 |
ISLETS, PANCREATIC | + | 7 |
PARATHYROID GLAND | M | 7 |
PITUITARY GLAND | M | 4 |
THYROID GLAND | + | 8 |
ULTIMOBRANCHIAL CYST | | 2 2.5|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + | 8 |
ATROPHY | 3 | 8 2.8|
OVARY | + + + + + + + + + + + + + + | 28 |
ATROPHY | X | 6 |
CYST | X X X X X X | 11 |
CYST,PERIOVARIAN TISSUE | X X X X X X X | 9 |
UTERUS | + + + + + + + + + + + + + + | 29 |
ATROPHY | 4 | 5 3.4|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 111
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:26.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 1| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| S R R|
| 5| 5| 5| 6| 4| 4| 4| 6| 6| 5| 5| 5| 5| 5| 5| 8| 8| 8| 9| 9| 9| 9| 9| U V I|
10MG FS-2YR 12 12 | 7| 8| 9| 0| 4| 5| 6| 6| 7| 3| 4| 5| 6| 7| 8| 0| 8| 9| 0| 1| 2| 3| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
DILATATION | 4 3 | 2 3.5|
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 3 2 4 2 2 2 3 2 2 2 | 19 2.3|
VAGINA | + | 8 |
ATROPHY | 4 | 5 3.6|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + | 8 |
DEPLETION | | 1 2.0|
HYPERPLASIA | | 1 3.0|
MYELOFIBROSIS | | 1 2.0|
LYMPH NODE | + + + + + + | 15 |
HYPERPLASIA,LYMPHOID,INGUINAL | 2 | 1 2.0|
LYMPH NODE,MANDIBULAR | + + | 9 |
HEMATOPOIETIC CELL PROLIFERATION | | 1 3.0|
LYMPH NODE,MESENTERIC | + + + + | 11 |
ATROPHY | | 2 3.0|
HEMATOPOIETIC CELL PROLIFERATION | | 1 3.0|
HEMORRHAGE | | 1 3.0|
SPLEEN | + + + + + + | 20 |
ATROPHY | | 2 3.0|
CONGESTION | 2 | 2 1.5|
HEMATOPOIETIC CELL PROLIFERATION | 3 | 4 3.0|
HYPERPLASIA,LYMPHOID | | 2 1.5|
THYMUS | + | 6 |
ATROPHY,CORTEX | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + | 6 |
HYPERPLASIA | | 1 3.0|
SKIN | + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 112
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:26.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 1| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| S R R|
| 5| 5| 5| 6| 4| 4| 4| 6| 6| 5| 5| 5| 5| 5| 5| 8| 8| 8| 9| 9| 9| 9| 9| U V I|
10MG FS-2YR 12 12 | 7| 8| 9| 0| 4| 5| 6| 6| 7| 3| 4| 5| 6| 7| 8| 0| 8| 9| 0| 1| 2| 3| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
BONE | + | 8 |
BONE,FEMUR | + | 8 |
BONE,STERNUM | + | 8 |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | | 2 2.0|
SKELETAL MUSCLE | + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + | 8 |
BRAIN,CEREBELLUM | + | 8 |
BRAIN,CEREBRUM | + | 8 |
MINERALIZATION,MULTIFOCAL,THALAMUS | | 4 1.0|
PERIPHERAL NERVE | + | 8 |
SPINAL CORD | + | 8 |
SPINAL CORD,THORACIC | + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + | 4 |
LUNG | + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 2 1.5|
NOSE | + | 8 |
TRACHEA | + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + | 5 |
HARDERIAN GLAND | + + | 10 |
HYPERPLASIA | | 1 4.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 2 1.0|
LACRIMAL GLAND | + | 5 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 3 1.0|
ZYMBAL'S GLAND | M | 6 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 113
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:26.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 1| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| S R R|
| 5| 5| 5| 6| 4| 4| 4| 6| 6| 5| 5| 5| 5| 5| 5| 8| 8| 8| 9| 9| 9| 9| 9| U V I|
10MG FS-2YR 12 12 | 7| 8| 9| 0| 4| 5| 6| 6| 7| 3| 4| 5| 6| 7| 8| 0| 8| 9| 0| 1| 2| 3| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM
KIDNEY | + + | 9 |
ACCUMULATION HYALINE DROPLET | | 1 4.0|
CYST,RENAL TUBULE | | 1 1.0|
GLOMERULOSCLEROSIS | | 2 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 4 1.5|
URETER | + | 1 |
URINARY BLADDER | + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 5 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 114
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:28.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 5| 2| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 1| 1| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| S R R|
| 0| 0| 0| 8| 8| 8| 9| 9| 9| 9| 9| 4| 4| 4| 4| 8| 8| 8| 8| 7| 7| 7| 7| 7| 7| U V I|
25MG FS-2YR 13 13 | 8| 9| 7| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 3| 4| 5| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + M | |
GALLBLADDER | + + + | |
INTESTINE LARGE | + + + | |
INTESTINE LARGE,CECUM | + A A | |
INTESTINE LARGE,COLON | + A + | |
INTESTINE LARGE,RECTUM | + + M | |
INTESTINE SMALL | + A A | |
INTESTINE SMALL,DUODENUM | + A A | |
INTESTINE SMALL,ILEUM | + A A | |
INTESTINE SMALL,JEJUNUM | + A A | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | 3 | |
BASOPHILIC FOCUS | X | |
DEGENERATION | 3 | |
EOSINOPHILIC FOCUS | X | |
HEMATOPOIETIC CELL PROLIFERATION | 1 1 1 1 | |
HYPERPLASIA,OVAL CELL | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 2 1 2 1 3 1 1 1 1 2 1 1 1 1| |
INFILTRATION CELLULAR,PLASMA CELL | | |
NECROSIS | 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1| |
NECROSIS,COAGULATIVE | 3 3 1 | |
REGENERATION | 3 | |
TENSION LIPOIDOSIS | X X X X X X X X X | |
THROMBUS | 3 | |
VACUOLIZATION CYTOPLASMIC | 3 2 2 3 3 3 2 1 2 3 2 2 1 2 2 2 2 2 2 2| |
MESENTERY | | |
PANCREAS | + + A | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
SALIVARY GLANDS | + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 | |
STOMACH | + A + | |
STOMACH,FORESTOMACH | + A + | |
HYPERKERATOSIS | 2 | |
STOMACH,GLANDULAR | + A + | |
TONGUE | + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 115
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:29.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 5| 2| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 1| 1| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| S R R|
| 0| 0| 0| 8| 8| 8| 9| 9| 9| 9| 9| 4| 4| 4| 4| 8| 8| 8| 8| 7| 7| 7| 7| 7| 7| U V I|
25MG FS-2YR 13 13 | 8| 9| 7| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 3| 4| 5| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + | |
BLOOD VESSEL,AORTA | + + + | |
HEART | + + + | |
NECROSIS | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + M | |
ADRENAL GLAND,CORTEX | + + M | |
HYPERPLASIA,SPINDLE CELL | 1 | |
ADRENAL GLAND,MEDULLA | + + M | |
ISLETS, PANCREATIC | + + A + | |
PARATHYROID GLAND | M M M | |
PITUITARY GLAND | M M M | |
THYROID GLAND | + + M | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + M M | |
ATROPHY | 4 | |
OVARY | + + M + + + + + + + + + + + + + + | |
ATROPHY | X | |
CYST | X X X X X X X X | |
CYST,PERIOVARIAN TISSUE | X X X X X X | |
HEMATOCYST | | |
UTERUS | + + + + + + + + + + + + + + + | |
ATROPHY | 4 4 | |
DILATATION | 2 4 4 2 | |
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 3 3 2 2 2 3 3 2 | |
INFLAMMATION | | |
VAGINA | + M M | |
ATROPHY | 4 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 116
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:29.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 5| 2| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 1| 1| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| S R R|
| 0| 0| 0| 8| 8| 8| 9| 9| 9| 9| 9| 4| 4| 4| 4| 8| 8| 8| 8| 7| 7| 7| 7| 7| 7| U V I|
25MG FS-2YR 13 13 | 8| 9| 7| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 3| 4| 5| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
BONE MARROW | + A A | |
LYMPH NODE | + + + + + | |
LYMPH NODE,MANDIBULAR | + + + | |
LYMPH NODE,MESENTERIC | + + M + | |
SPLEEN | + + + + + + | |
ATROPHY | 2 | |
CONGESTION | | |
HEMATOPOIETIC CELL PROLIFERATION | 3 | |
HYPERPLASIA,LYMPHOID | 3 | |
THYMUS | + + M + | |
ATROPHY,CORTEX | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + M | |
SKIN | + + + | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + | |
BONE,FEMUR | + M + | |
BONE,STERNUM | + + + | |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 3 | |
SKELETAL MUSCLE | + + + | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + | |
BRAIN,CEREBELLUM | + + + | |
BRAIN,CEREBRUM | + + + | |
PERIPHERAL NERVE | + + + | |
SPINAL CORD | + + + | |
SPINAL CORD,THORACIC | + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 117
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:29.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 7| 5| 2| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 1| 1| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| S R R|
| 0| 0| 0| 8| 8| 8| 9| 9| 9| 9| 9| 4| 4| 4| 4| 8| 8| 8| 8| 7| 7| 7| 7| 7| 7| U V I|
25MG FS-2YR 13 13 | 8| 9| 7| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 3| 4| 5| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM
LARYNX | + + M | |
LUNG | + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 | |
NOSE | + + + | |
TRACHEA | + + M | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | A A A | |
HARDERIAN GLAND | + + + + | |
HYPERPLASIA | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | |
LACRIMAL GLAND | + + M | |
ZYMBAL'S GLAND | M M + | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | |
URINARY BLADDER | + + M | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 118
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:30.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| S R R|
| 7| 0| 0| 0| 0| 0| 0| 0| 0| 6| 6| 6| 6| 7| 7| 7| 2| 2| 2| 2| 2| 2| 2| U V I|
25MG FS-2YR 13 13 | 9| 2| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | | 2 |
GALLBLADDER | | 3 |
INTESTINE LARGE | | 3 |
INTESTINE LARGE,CECUM | | 1 |
INTESTINE LARGE,COLON | | 2 |
INTESTINE LARGE,RECTUM | | 2 |
INTESTINE SMALL | + | 2 |
INTESTINE SMALL,DUODENUM | | 1 |
INTESTINE SMALL,ILEUM | | 1 |
INTESTINE SMALL,JEJUNUM | + | 2 |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ANGIECTASIS | | 1 3.0|
BASOPHILIC FOCUS | X | 2 |
DEGENERATION | | 1 3.0|
EOSINOPHILIC FOCUS | | 1 |
HEMATOPOIETIC CELL PROLIFERATION | 1 1 1 1 1 1 1 1 1 | 13 1.0|
HYPERPLASIA,OVAL CELL | | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 2 1 2 1 1 1 1 1 1 1 1 2 | 36 1.2|
INFILTRATION CELLULAR,PLASMA CELL | 1 | 1 1.0|
NECROSIS | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 | 40 1.0|
NECROSIS,COAGULATIVE | 2 | 4 2.2|
REGENERATION | | 1 3.0|
TENSION LIPOIDOSIS | X X X X X X X X X X X | 20 |
THROMBUS | | 1 3.0|
VACUOLIZATION CYTOPLASMIC | 2 1 1 1 2 2 1 1 2 2 1 1 2 2 1 2 2 3 2 2 1 2 | 42 1.8|
MESENTERY | + | 1 |
PANCREAS | | 2 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
SALIVARY GLANDS | | 3 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 3 1.3|
STOMACH | | 2 |
STOMACH,FORESTOMACH | | 2 |
HYPERKERATOSIS | | 1 2.0|
STOMACH,GLANDULAR | | 2 |
TONGUE | | 3 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 119
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:30.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| S R R|
| 7| 0| 0| 0| 0| 0| 0| 0| 0| 6| 6| 6| 6| 7| 7| 7| 2| 2| 2| 2| 2| 2| 2| U V I|
25MG FS-2YR 13 13 | 9| 2| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | | 3 |
BLOOD VESSEL,AORTA | | 3 |
HEART | | 3 |
NECROSIS | | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | | 2 |
ADRENAL GLAND,CORTEX | | 2 |
HYPERPLASIA,SPINDLE CELL | | 1 1.0|
ADRENAL GLAND,MEDULLA | | 2 |
ISLETS, PANCREATIC | | 3 |
PARATHYROID GLAND | | 0 |
PITUITARY GLAND | | 0 |
THYROID GLAND | | 2 |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | | 1 |
ATROPHY | | 1 4.0|
OVARY | + + + + + + + + + + + + | 28 |
ATROPHY | | 1 |
CYST | X X X X X X X X X | 17 |
CYST,PERIOVARIAN TISSUE | X | 7 |
HEMATOCYST | X | 1 |
UTERUS | + + + + + + + + + + + + + | 28 |
ATROPHY | | 2 4.0|
DILATATION | 3 4 3 2 | 8 3.0|
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 3 2 4 2 2 4 2 2 | 17 2.5|
INFLAMMATION | 2 | 1 2.0|
VAGINA | | 1 |
ATROPHY | | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 120
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:30.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| S R R|
| 7| 0| 0| 0| 0| 0| 0| 0| 0| 6| 6| 6| 6| 7| 7| 7| 2| 2| 2| 2| 2| 2| 2| U V I|
25MG FS-2YR 13 13 | 9| 2| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
BONE MARROW | | 1 |
LYMPH NODE | + | 6 |
LYMPH NODE,MANDIBULAR | + | 4 |
LYMPH NODE,MESENTERIC | + | 4 |
SPLEEN | + + + + + + + + + | 15 |
ATROPHY | | 1 2.0|
CONGESTION | 1 | 1 1.0|
HEMATOPOIETIC CELL PROLIFERATION | 4 | 2 3.5|
HYPERPLASIA,LYMPHOID | 2 1 3 | 4 2.2|
THYMUS | + | 4 |
ATROPHY,CORTEX | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | | 2 |
SKIN | + + + | 6 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | | 3 |
BONE,FEMUR | | 2 |
BONE,STERNUM | | 3 |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | | 1 3.0|
SKELETAL MUSCLE | | 3 |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | | 3 |
BRAIN,CEREBELLUM | | 3 |
BRAIN,CEREBRUM | | 3 |
PERIPHERAL NERVE | | 3 |
SPINAL CORD | | 3 |
SPINAL CORD,THORACIC | | 3 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 121
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:30.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| S R R|
| 7| 0| 0| 0| 0| 0| 0| 0| 0| 6| 6| 6| 6| 7| 7| 7| 2| 2| 2| 2| 2| 2| 2| U V I|
25MG FS-2YR 13 13 | 9| 2| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM
LARYNX | | 2 |
LUNG | + | 4 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 2 1.5|
NOSE | | 3 |
TRACHEA | | 2 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | | 0 |
HARDERIAN GLAND | + | 5 |
HYPERPLASIA | 4 | 1 4.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 2 1.0|
LACRIMAL GLAND | | 2 |
ZYMBAL'S GLAND | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | | 3 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 2 1.0|
URINARY BLADDER | | 2 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 122
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:45.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 5| 5| 6| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 5| 0| 4| 4| 0| 5| 5| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 8| 2| 4| 7| 0| 8| 6| 6| 6| 6| 6| 6| 6| 6| 6| 4| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 1| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| S R R|
| 3| 6| 6| 7| 7| 0| 2| 7| 8| 8| 8| 8| 8| 8| 8| 2| 4| 4| 4| 7| 7| 7| 7| 6| 6| U V I|
50MG FS-2YR 14 14 | 9| 3| 4| 1| 0| 5| 3| 9| 0| 1| 2| 3| 4| 5| 6| 3| 3| 4| 5| 6| 7| 8| 9| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + + + + + + + + + + M + + + + + + | |
HYPERKERATOSIS | 2 | |
GALLBLADDER | M + + A + + A + + + + + + + + + + + + + + + + + + | |
ACCUMULATION HYALINE DROPLET | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
INTESTINE LARGE | A + + A + + A + + + + + + + + A + + + + + + + + + | |
INTESTINE LARGE,CECUM | A + + A + + A + + + + + + + + A + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | | |
INTESTINE LARGE,COLON | A + + A + + A + + + + + + + + A + + + + + + + + + | |
HYPERPLASIA,GOBLET CELL | 2 | |
INTESTINE LARGE,RECTUM | A + + A + + A + + + + + + + + A + + + + + + + + + | |
INTESTINE SMALL | A + + A + + A + + + + + + + + A + + + + + + + + + | |
INTESTINE SMALL,DUODENUM | A + + A M A A + + + + + + + + A + + + + + + + + + | |
INTESTINE SMALL,ILEUM | A + + A + A A + + + + + + + + A + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | 1 2 | |
INTESTINE SMALL,JEJUNUM | A + + A + + A + + + + + + + + A + + + + + + + + + | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BASOPHILIC FOCUS | | |
DEGENERATION | | |
HEMATOPOIETIC CELL PROLIFERATION | 2 1 1| |
HYPERPLASIA,KUPFFER CELL | 3 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 3 1 1 1 1 2 1 1 2 2 1 1 1 1 1| |
INFLAMMATION | 1 | |
NECROSIS | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 3 1 1| |
NECROSIS,COAGULATIVE | 1 | |
TENSION LIPOIDOSIS | X X X X X X X | |
THROMBUS | 1 | |
VACUOLIZATION CYTOPLASMIC | 1 4 4 2 1 2 1 2 2 2 1 2 2 2| |
PANCREAS | A + + + + + A + + + + + + + + + + + + + + + + + + | |
ACCUMULATION HYALINE DROPLET,DUCT | | |
DEGENERATION | 1 | |
FOCAL CELLULAR CHANGE | 1 | |
INFILTRATION CELLULAR,HISTIOCYTIC | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 1 2 1 1 2 1 | |
NECROSIS | 1 | |
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 123
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:45.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 5| 5| 6| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 5| 0| 4| 4| 0| 5| 5| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 8| 2| 4| 7| 0| 8| 6| 6| 6| 6| 6| 6| 6| 6| 6| 4| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 1| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| S R R|
| 3| 6| 6| 7| 7| 0| 2| 7| 8| 8| 8| 8| 8| 8| 8| 2| 4| 4| 4| 7| 7| 7| 7| 6| 6| U V I|
50MG FS-2YR 14 14 | 9| 3| 4| 1| 0| 5| 3| 9| 0| 1| 2| 3| 4| 5| 6| 3| 3| 4| 5| 6| 7| 8| 9| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ATROPHY | 2 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 2 1 2 1 1 1 1 2 2 2 1 1 1 1 2 1 1 2| |
STOMACH | A + + A + + A + + + + + + + + A + + + + + + + + + | |
STOMACH,FORESTOMACH | A + + A + + A + + + + + + + + A + + + + + + + + + | |
HYPERKERATOSIS | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
INFLAMMATION | | |
STOMACH,GLANDULAR | A + + A + + A + + + + + + + + A + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
INFLAMMATION | | |
MINERALIZATION | 1 | |
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
POLYARTERITIS | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + M M + + + + + + + + M + + M + + + + + M + + + | |
BLOOD VESSEL,AORTA | + + M M + + + + + + + + M + + M + + + + + M + + + | |
HEART | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DEGENERATION,VALVE | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
NECROSIS | 2 | |
POLYARTERITIS | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | | |
HYPERPLASIA,SPINDLE CELL | 2 2 2 1 2 1 1 2 2 2 2 1 2 2 1 2 2 2 1 | |
VACUOLIZATION CYTOPLASMIC | 2 1 | |
ADRENAL GLAND,MEDULLA | + + + + + + + + + + + + + + + + M + + + + + + + | |
ISLETS, PANCREATIC | A + + A + + A + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | 2 | |
PARATHYROID GLAND | + M + + + + + + + + + + + + + + + + + + + + M + M | |
ECTOPIC THYMUS | X | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 124
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:45.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 5| 5| 6| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 5| 0| 4| 4| 0| 5| 5| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 8| 2| 4| 7| 0| 8| 6| 6| 6| 6| 6| 6| 6| 6| 6| 4| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 1| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| S R R|
| 3| 6| 6| 7| 7| 0| 2| 7| 8| 8| 8| 8| 8| 8| 8| 2| 4| 4| 4| 7| 7| 7| 7| 6| 6| U V I|
50MG FS-2YR 14 14 | 9| 3| 4| 1| 0| 5| 3| 9| 0| 1| 2| 3| 4| 5| 6| 3| 3| 4| 5| 6| 7| 8| 9| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
PITUITARY GLAND | + + M + + + + + + + + + + + + + + + + + M + + + + | |
ANGIECTASIS | | |
HYPERPLASIA,PARS DISTALIS | 3 3 1 2 2 1 | |
POLYARTERITIS | 2 | |
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DEGENERATION | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
POLYARTERITIS | 2 | |
ULTIMOBRANCHIAL CYST | 2 2 3 2 3 3 2 3 2 2 | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + + + + M + + M + + M M + M M + + + + + + + + + | |
ATROPHY | 4 3 3 4 2 2 3 2 4 1 3 3 3 2 3| |
OVARY | + + + + + + + + + + + + + + + M + + + M + + + + + | |
ANGIECTASIS | | |
ATROPHY | X X X X X X X X X X X X X X X X X X | |
CYST | X X X X X | |
CYST,PERIOVARIAN TISSUE | X | |
HEMATOCYST | X | |
MINERALIZATION | | |
UTERUS | + + + A + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 4 3 4 3 | |
DILATATION | 4 4 | |
FIBROSIS | 3 | |
HEMORRHAGE | 4 | |
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 2 2 1 1 3 4 4 2 2 2 3 2 2 1 2| |
INFLAMMATION | | |
VAGINA | A + + + + + + + + + + + + + + + + + + M + + + + + | |
ATROPHY | 4 4 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
POLYARTERITIS | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 125
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:45.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 5| 5| 6| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 5| 0| 4| 4| 0| 5| 5| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 8| 2| 4| 7| 0| 8| 6| 6| 6| 6| 6| 6| 6| 6| 6| 4| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 1| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| S R R|
| 3| 6| 6| 7| 7| 0| 2| 7| 8| 8| 8| 8| 8| 8| 8| 2| 4| 4| 4| 7| 7| 7| 7| 6| 6| U V I|
50MG FS-2YR 14 14 | 9| 3| 4| 1| 0| 5| 3| 9| 0| 1| 2| 3| 4| 5| 6| 3| 3| 4| 5| 6| 7| 8| 9| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + A + + + + + + + + + + + A + + + + + + + + + | |
HYPERPLASIA | 4 | |
INFARCT | | |
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | 2 | |
HYPERPLASIA,LYMPHOID | 2 | |
LYMPH NODE,MESENTERIC | + M + + + + + + + + + + + + + + + + + + + + + + M | |
ATROPHY | 1 | |
HEMORRHAGE | 2 | |
HYPERPLASIA,LYMPHOID | 2 | |
SPLEEN | A + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 | |
HEMATOPOIETIC CELL PROLIFERATION | 4 4 2 2 2 2 | |
HYPERPLASIA,LYMPHOID | 3 2 2 1 1 3 3 2 2 | |
INFARCT | 1 | |
THYMUS | M + + M + + M + + + + + + M + M + + + + + M + + + | |
ATROPHY,CORTEX | 2 3 4 4 3 2 3 4 3 2 2 3 3| |
CONGESTION | | |
HYPERPLASIA,LYMPHOID,MEDULLA | 2 2 2 1 2 1 2 2 2 3| |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + + + + + + + + + + + + A + + + + + + + + + | |
HYPERPLASIA | 2 | |
LACTATION | 3 | |
SKIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + A + + + + + + + + + + + + + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY,TURBINATE | 1 1 | |
BONE,FEMUR | + + + A + + + + + + + + + + + + + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY | 1 1 1 1 2 1| |
BONE,STERNUM | + + + A + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 126
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:45.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 5| 5| 6| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 5| 0| 4| 4| 0| 5| 5| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 8| 2| 4| 7| 0| 8| 6| 6| 6| 6| 6| 6| 6| 6| 6| 4| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 1| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| S R R|
| 3| 6| 6| 7| 7| 0| 2| 7| 8| 8| 8| 8| 8| 8| 8| 2| 4| 4| 4| 7| 7| 7| 7| 6| 6| U V I|
50MG FS-2YR 14 14 | 9| 3| 4| 1| 0| 5| 3| 9| 0| 1| 2| 3| 4| 5| 6| 3| 3| 4| 5| 6| 7| 8| 9| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 1 1 2 2 3 2 2 1 1 2 2 1 2| |
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 1 1 1 1 1 1 1 2 1 2 1 1 2 1 1 | |
PERIPHERAL NERVE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + + + | |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | M + + M + + + + + + + + + + + + + M + M + + + + + | |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CONGESTION | 4 | |
HYPERPLASIA,ALVEOLAR EPITHELIUM | | |
INFILTRATION CELLULAR,HISTIOCYTIC | 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 2 1 1 1 2 1 1 1 1 2 1 1 1 1| |
INFLAMMATION | 1 | |
NOSE | + + + A + + + + + + + + + + + + + + + + + + + + + | |
FOCAL CELLULAR CHANGE | | |
TRACHEA | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | A + + A + + + + + + + + + + + + + + + + + + + + + | |
INFLAMMATION,CORNEA | | |
HARDERIAN GLAND | + + + + + + + M + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 1 1 1 1 1| |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 127
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:46.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 5| 5| 6| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 5| 0| 4| 4| 0| 5| 5| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 8| 2| 4| 7| 0| 8| 6| 6| 6| 6| 6| 6| 6| 6| 6| 4| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 1| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| S R R|
| 3| 6| 6| 7| 7| 0| 2| 7| 8| 8| 8| 8| 8| 8| 8| 2| 4| 4| 4| 7| 7| 7| 7| 6| 6| U V I|
50MG FS-2YR 14 14 | 9| 3| 4| 1| 0| 5| 3| 9| 0| 1| 2| 3| 4| 5| 6| 3| 3| 4| 5| 6| 7| 8| 9| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
LACRIMAL GLAND | + + + + M + + + + + + + M + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 2 2 1 1 1 2 2 1 1 2 2| |
ZYMBAL'S GLAND | + + M + + + + + + + + + + + + + + + + + + + + + + | |
INFLAMMATION | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ACCUMULATION HYALINE DROPLET | 3 | |
CYST,RENAL TUBULE | 1 1 | |
GLOMERULOSCLEROSIS | | |
HYDRONEPHROSIS | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 3 1 1 1 1 1 1 1 1 1 1| |
MINERALIZATION | 1 | |
NEPHROPATHY | | |
PIGMENTATION,RENAL TUBULE | 3 | |
URINARY BLADDER | A + + + + + + + + + + + + + + A + + + + + + M + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 2 1 1 1 1 1 1 1 1 2 1 1 1 2 1| |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 128
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:58.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 6| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| S R R|
| 6| 7| 7| 7| 9| 9| 9| 9| 0| 0| 5| 6| 6| 6| 6| 6| 6| 1| 1| 1| 2| 2| 2| U V I|
50MG FS-2YR 14 14 | 9| 0| 1| 2| 6| 7| 8| 9| 0| 1| 9| 0| 1| 2| 3| 4| 5| 7| 8| 9| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + M + + + + + + + + + + + + + | 46 |
HYPERKERATOSIS | | 1 2.0|
GALLBLADDER | + + + + + + + + + + + + + + + + M + + + + + + | 44 |
ACCUMULATION HYALINE DROPLET | 2 | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 2 1.0|
INTESTINE LARGE | + + + + + + + + + + + + + + + + + + + + + + + | 44 |
INTESTINE LARGE,CECUM | + + + + + + + + + + + + + + + + + + + + + + | 43 |
HYPERPLASIA,LYMPHOID | 1 | 1 1.0|
INTESTINE LARGE,COLON | + + + + + + + + + + + + + + + + + + + + + + | 43 |
HYPERPLASIA,GOBLET CELL | | 1 2.0|
INTESTINE LARGE,RECTUM | + + + + + + + + + + + + + + + + + + + + + + | 43 |
INTESTINE SMALL | + + + + + + + + + + + + + + + + + + + + + + + | 44 |
INTESTINE SMALL,DUODENUM | + + + + + + + + + + + + + + + + + + + + + + M | 41 |
INTESTINE SMALL,ILEUM | + + + + + + + + + + + + + + + + + + + + + + + | 43 |
HYPERPLASIA,LYMPHOID | 1 2 | 4 1.5|
INTESTINE SMALL,JEJUNUM | + + + + + + + + + + + + + + + + + + + + + + + | 44 |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BASOPHILIC FOCUS | X | 1 |
DEGENERATION | 3 | 1 3.0|
HEMATOPOIETIC CELL PROLIFERATION | 1 1 1 1 1 2 1 1 | 11 1.1|
HYPERPLASIA,KUPFFER CELL | | 1 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 3 1 1 1 1 1 1 | 33 1.2|
INFLAMMATION | | 1 1.0|
NECROSIS | 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 | 34 1.0|
NECROSIS,COAGULATIVE | 3 1 | 3 1.6|
TENSION LIPOIDOSIS | X X X X X X X X X | 16 |
THROMBUS | | 1 1.0|
VACUOLIZATION CYTOPLASMIC | 2 2 2 2 2 2 2 3 2 2 2 1 2 1 1 2 2 2 2 3 | 34 1.9|
PANCREAS | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
ACCUMULATION HYALINE DROPLET,DUCT | 2 | 1 2.0|
DEGENERATION | | 1 1.0|
FOCAL CELLULAR CHANGE | 1 | 2 1.0|
INFILTRATION CELLULAR,HISTIOCYTIC | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 | 20 1.1|
NECROSIS | | 1 1.0|
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 129
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:58.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 6| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| S R R|
| 6| 7| 7| 7| 9| 9| 9| 9| 0| 0| 5| 6| 6| 6| 6| 6| 6| 1| 1| 1| 2| 2| 2| U V I|
50MG FS-2YR 14 14 | 9| 0| 1| 2| 6| 7| 8| 9| 0| 1| 9| 0| 1| 2| 3| 4| 5| 7| 8| 9| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ATROPHY | | 2 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 1 1 1 1 1 1 1 1 2 1 1 1 2 1 1 1 2 | 41 1.2|
STOMACH | + + + + + + + + + + + + + + + + + + + + + + + | 44 |
STOMACH,FORESTOMACH | + + + + + + + + + + + + + + + + + + + + + + + | 44 |
HYPERKERATOSIS | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 1 2.0|
INFLAMMATION | 1 1 | 2 1.0|
STOMACH,GLANDULAR | + + + + + + + + + + + + + + + + + + + + + + + | 44 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 1 2.0|
INFLAMMATION | 1 | 1 1.0|
MINERALIZATION | 1 | 2 1.0|
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
POLYARTERITIS | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + + + + + + + + + + + + + + + + | 43 |
BLOOD VESSEL,AORTA | + + + + + + + + + + + + + + + + + + + + + + + | 43 |
HEART | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
DEGENERATION,VALVE | 1 1 2 | 4 1.2|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
NECROSIS | | 1 2.0|
POLYARTERITIS | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + M + + + + + + + + + + + + M + + + + | 46 |
ADRENAL GLAND,CORTEX | + + + + + M + + + + + + + + + + + + M + + + + | 46 |
HYPERPLASIA | 1 | 1 1.0|
HYPERPLASIA,SPINDLE CELL | 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 | 38 1.3|
VACUOLIZATION CYTOPLASMIC | | 2 1.5|
ADRENAL GLAND,MEDULLA | + + + + + M + + + + + + + + + + + + M + + + + | 44 |
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
HYPERPLASIA | 1 | 2 1.5|
PARATHYROID GLAND | + + + + + + + + + M + + + + + + + + + + + + + | 44 |
ECTOPIC THYMUS | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 130
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:58.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 6| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| S R R|
| 6| 7| 7| 7| 9| 9| 9| 9| 0| 0| 5| 6| 6| 6| 6| 6| 6| 1| 1| 1| 2| 2| 2| U V I|
50MG FS-2YR 14 14 | 9| 0| 1| 2| 6| 7| 8| 9| 0| 1| 9| 0| 1| 2| 3| 4| 5| 7| 8| 9| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
PITUITARY GLAND | + + + + + + M + + + + M + M + M + + + + + + + | 42 |
ANGIECTASIS | 1 | 1 1.0|
HYPERPLASIA,PARS DISTALIS | 1 1 | 8 1.7|
POLYARTERITIS | | 1 2.0|
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
DEGENERATION | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 2 1.0|
POLYARTERITIS | | 1 2.0|
ULTIMOBRANCHIAL CYST | 2 2 2 2 3 3 2 2 2 2 | 20 2.3|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + + + + + + + + + M + + + M + M + + M M + + | 37 |
ATROPHY | 3 3 3 2 2 2 2 2 1 1 2 1 2 2 | 29 2.4|
OVARY | + + + + + + + + M + + + + + + + + + + + + + + | 45 |
ANGIECTASIS | 3 | 1 3.0|
ATROPHY | X X X X X X X X X X X X X X X | 33 |
CYST | X X X X X X X X | 13 |
CYST,PERIOVARIAN TISSUE | X X | 3 |
HEMATOCYST | X X | 3 |
MINERALIZATION | 2 | 1 2.0|
UTERUS | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ATROPHY | | 4 3.5|
DILATATION | 1 | 3 3.0|
FIBROSIS | 2 | 2 2.5|
HEMORRHAGE | | 1 4.0|
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 3 2 3 2 1 2 4 2 1 2 2 1 1 1 4 1 1 3 2 3 1 2 | 38 2.0|
INFLAMMATION | 1 | 1 1.0|
VAGINA | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
ATROPHY | | 2 4.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 2 1.0|
POLYARTERITIS | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 131
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:59.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 6| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| S R R|
| 6| 7| 7| 7| 9| 9| 9| 9| 0| 0| 5| 6| 6| 6| 6| 6| 6| 1| 1| 1| 2| 2| 2| U V I|
50MG FS-2YR 14 14 | 9| 0| 1| 2| 6| 7| 8| 9| 0| 1| 9| 0| 1| 2| 3| 4| 5| 7| 8| 9| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
HYPERPLASIA | 3 | 2 3.5|
INFARCT | X | 1 |
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
LYMPH NODE,MANDIBULAR | + M + + + + + + + + + + + + + + + + + + + + + | 47 |
HYPERPLASIA | | 1 2.0|
HYPERPLASIA,LYMPHOID | 3 1 | 3 2.0|
LYMPH NODE,MESENTERIC | + + + + + + + + + + M + + M + + + + + + M + + | 43 |
ATROPHY | | 1 1.0|
HEMORRHAGE | | 1 2.0|
HYPERPLASIA,LYMPHOID | | 1 2.0|
SPLEEN | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
ATROPHY | | 1 3.0|
HEMATOPOIETIC CELL PROLIFERATION | 2 3 2 | 9 2.5|
HYPERPLASIA,LYMPHOID | 2 3 2 | 12 2.1|
INFARCT | | 1 1.0|
THYMUS | + + + + + M M + M M + + + + M + + + + + + + + | 37 |
ATROPHY,CORTEX | 4 2 | 15 2.9|
CONGESTION | 2 | 1 2.0|
HYPERPLASIA,LYMPHOID,MEDULLA | 2 2 1 2 2 1 2 1 1 2 2 2 | 22 1.7|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HYPERPLASIA | | 1 2.0|
LACTATION | 1 1 1 2 | 5 1.6|
SKIN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
FIBROUS OSTEODYSTROPHY,TURBINATE | 1 1 1 1 1 1 1 2 | 10 1.1|
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
FIBROUS OSTEODYSTROPHY | 2 2 1 | 9 1.3|
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 132
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:59.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 6| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| S R R|
| 6| 7| 7| 7| 9| 9| 9| 9| 0| 0| 5| 6| 6| 6| 6| 6| 6| 1| 1| 1| 2| 2| 2| U V I|
50MG FS-2YR 14 14 | 9| 0| 1| 2| 6| 7| 8| 9| 0| 1| 9| 0| 1| 2| 3| 4| 5| 7| 8| 9| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 1 1 2 2 1 1 1 1 1 2 1 1 2 2 2 1 2 2 1 1 | 33 1.5|
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 2 1.0|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 2 1.0|
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 1 1 2 1 1 | 24 1.1|
PERIPHERAL NERVE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + M + + + + M + + + + + + + + + + + + + | 42 |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
CONGESTION | | 1 4.0|
HYPERPLASIA,ALVEOLAR EPITHELIUM | 1 | 1 1.0|
INFILTRATION CELLULAR,HISTIOCYTIC | | 2 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 1 1 1 1 1 1 2 1 1 3 2 1 1 1 2 1 | 38 1.2|
INFLAMMATION | | 1 1.0|
NOSE | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
FOCAL CELLULAR CHANGE | 1 | 1 1.0|
TRACHEA | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
INFLAMMATION,CORNEA | 1 | 1 1.0|
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HYPERPLASIA | 1 | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 | 16 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 133
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:37:59.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 6| 6| 6| 6| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| S R R|
| 6| 7| 7| 7| 9| 9| 9| 9| 0| 0| 5| 6| 6| 6| 6| 6| 6| 1| 1| 1| 2| 2| 2| U V I|
50MG FS-2YR 14 14 | 9| 0| 1| 2| 6| 7| 8| 9| 0| 1| 9| 0| 1| 2| 3| 4| 5| 7| 8| 9| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
LACRIMAL GLAND | + + + + + + + + M + + + + + M + + M + + + + + | 43 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 2 1 1 1 1 1 3 1 1 1 2 | 26 1.4|
ZYMBAL'S GLAND | + + + + M + + + + + + + + M + + + + + + + + + | 45 |
INFLAMMATION | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ACCUMULATION HYALINE DROPLET | | 1 3.0|
CYST,RENAL TUBULE | | 2 1.0|
GLOMERULOSCLEROSIS | 1 | 1 1.0|
HYDRONEPHROSIS | | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 | 39 1.1|
MINERALIZATION | | 1 1.0|
NEPHROPATHY | 2 1 | 2 1.5|
PIGMENTATION,RENAL TUBULE | | 1 3.0|
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 1 | 37 1.1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 134
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:12.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2| 3| 6| 6|
| 7| 2| 3| 7| 9| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 8| 5| 5|
| 8| 6| 3| 3| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 3| 3| 3| 3| 7| 8| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| S R R|
| 5| 7| 8| 8| 9| 1| 1| 4| 4| 4| 7| 7| 7| 7| 0| 0| 0| 4| 4| 4| 4| 6| 6| 9| 9| U V I|
CONTRL FS-2YR 19 19 | 7| 3| 1| 7| 5| 5| 6| 4| 5| 6| 3| 4| 5| 6| 4| 5| 6| 5| 6| 7| 8| 6| 9| 3| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | A + + + + + + + + + + + + + + + + + + + + M + + + | |
HYPERKERATOSIS | 2 2 | |
GALLBLADDER | M + + + + + + M M + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | |
INTESTINE LARGE | A + + + + + + + + + + + + + + + + + + + + M A + + | |
INTESTINE LARGE,CECUM | A + + + + + + + + + + + + + + + + + + + + M A + + | |
HYPERPLASIA,LYMPHOID | 2 2 | |
INTESTINE LARGE,COLON | A + + + + + + + + + + + + + + + + + + + + M A + + | |
HYPERPLASIA,LYMPHOID | | |
INTESTINE LARGE,RECTUM | A + + + + + + + + + + + + + + + + + + + + M A + + | |
INTESTINE SMALL | A + + + + + + + + + + + + + + + + + + + + + A + + | |
INTESTINE SMALL,DUODENUM | A + + + + + + + + + + + + + + + + + + + + + A + + | |
INTESTINE SMALL,ILEUM | A + + + + + + + M + M + + + + + + + + + + + A + + | |
INTESTINE SMALL,JEJUNUM | A + + + + + + + M + + + + + + + + + + + + + A + + | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BASOPHILIC FOCUS | X | |
EOSINOPHILIC FOCUS | X | |
HEMATOPOIETIC CELL PROLIFERATION | 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 1 1 1 1 1 1 1 1 1 1 | |
INFLAMMATION | | |
NECROSIS | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 | |
TENSION LIPOIDOSIS | X X X X X X X X | |
VACUOLIZATION CYTOPLASMIC | 2 1 1 1 1 1 1 1 1 1 2 1 1| |
MESENTERY | + | |
NECROSIS,FAT | 4 | |
PANCREAS | A + + + + + + + + + + + + + + + + + + + + + A + + | |
FOCAL CELLULAR CHANGE | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1| |
INFLAMMATION | | |
SALIVARY GLANDS | A + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 2| |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 2 1 1 1 1 1 1 1 2 1 2 1 1 2| |
STOMACH | A + + + + + + + + + + + + + + + + + + + + + A + + | |
STOMACH,FORESTOMACH | A + + + + + + + + + + + + + + + + + + + + + A + + | |
HYPERKERATOSIS | | |
STOMACH,GLANDULAR | A + + + + + + + + + + + + + + + + + + + + + A + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 135
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:12.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2| 3| 6| 6|
| 7| 2| 3| 7| 9| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 8| 5| 5|
| 8| 6| 3| 3| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 3| 3| 3| 3| 7| 8| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| S R R|
| 5| 7| 8| 8| 9| 1| 1| 4| 4| 4| 7| 7| 7| 7| 0| 0| 0| 4| 4| 4| 4| 6| 6| 9| 9| U V I|
CONTRL FS-2YR 19 19 | 7| 3| 1| 7| 5| 5| 6| 4| 5| 6| 3| 4| 5| 6| 4| 5| 6| 5| 6| 7| 8| 6| 9| 3| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
CYST | | |
TONGUE | A + + + A + + + + + + + + + + + + + + + + + + + + | |
INFLAMMATION | | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | M + M M + + + + + + + + + + + + + + M + + + + + + | |
BLOOD VESSEL,AORTA | M + M M + + + + + + + + + + + + + + M + + + + + + | |
HEART | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DEGENERATION,ARTERY | | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | A + + + + + + + + + + + + + + + + + + + + + + + + | |
ADRENAL GLAND,CORTEX | A + + + + + + + + + + + + + + + + + + + + + + + + | |
CYST | | |
FOCAL CELLULAR CHANGE | | |
HYPERPLASIA,SPINDLE CELL | 2 2 3 1 3 2 2 2 3 2 2 2 1 2 2 1 2 2 2 2 2 1 1| |
VACUOLIZATION CYTOPLASMIC | | |
ADRENAL GLAND,MEDULLA | A + + + + + + + + + + + + + + + + + + + + + + + + | |
FOCAL CELLULAR CHANGE | 2| |
VACUOLIZATION CYTOPLASMIC | | |
ISLETS, PANCREATIC | A + + + + + + + + + + + + + + + + + + + + + A + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
PARATHYROID GLAND | A + + + + + + + M + + + + + + + + + + + + M + + + | |
CYST | | |
ECTOPIC THYMUS | X | |
PITUITARY GLAND | A + + + + + + + + + + + + + + + + + + + + M M + + | |
ECTASIA | 1 | |
HYPERPLASIA,PARS DISTALIS | 1 3 | |
THYROID GLAND | A + + + + + + + + + + + + + + + + + + + + M + + + | |
CYST,FOLLICLE | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 | |
ULTIMOBRANCHIAL CYST | 2 3 2 2 4 2 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 136
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:12.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2| 3| 6| 6|
| 7| 2| 3| 7| 9| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 8| 5| 5|
| 8| 6| 3| 3| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 3| 3| 3| 3| 7| 8| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| S R R|
| 5| 7| 8| 8| 9| 1| 1| 4| 4| 4| 7| 7| 7| 7| 0| 0| 0| 4| 4| 4| 4| 6| 6| 9| 9| U V I|
CONTRL FS-2YR 19 19 | 7| 3| 1| 7| 5| 5| 6| 4| 5| 6| 3| 4| 5| 6| 4| 5| 6| 5| 6| 7| 8| 6| 9| 3| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
CLITORAL GLAND | A + + + + + + + + + + M + M + + + + M M + M M + + | |
ATROPHY | 4 2 3 3 3 3 3 3 3 4 3 4 3 3 4 3 4 3| |
INFLAMMATION | | |
OVARY | A + + + + + + + + + + + + + + + + + + + + + A + + | |
ATROPHY | X X X X X X X X X X X X X X | |
CYST | X X X X X X X | |
CYST,PERIOVARIAN TISSUE | X | |
HEMATOCYST | X X | |
HYPERPLASIA,ADENOMATOUS | | |
HYPERPLASIA,TUBULAR | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
OVOTESTIS | | |
UTERUS | + + + + + + + + + + + + + + + + + + + + + + A + + | |
ATROPHY | 3 3 3 2| |
DILATATION | 2 | |
ECTASIA,VEIN | | |
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 2 2 3 3 3 2 2 3 3 2 3 3 3 2 3 3 | |
METAPLASIA,SQUAMOUS | | |
THROMBUS | | |
VAGINA | A + + M + + + + + + + + + + + + + + + + + + A + + | |
ATROPHY | 2| |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | A + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | 3 | |
HYPERPLASIA,LYMPHOID | 2 | |
LYMPH NODE | A + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID,AXILLARY | | |
LYMPH NODE,MANDIBULAR | A + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 2| |
HEMORRHAGE | | |
HYPERPLASIA,LYMPHOID | 2 3 4 | |
LYMPH NODE,MESENTERIC | A + + + + + + + + + + + + + + + + + + + + + M + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 137
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:12.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2| 3| 6| 6|
| 7| 2| 3| 7| 9| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 8| 5| 5|
| 8| 6| 3| 3| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 3| 3| 3| 3| 7| 8| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| S R R|
| 5| 7| 8| 8| 9| 1| 1| 4| 4| 4| 7| 7| 7| 7| 0| 0| 0| 4| 4| 4| 4| 6| 6| 9| 9| U V I|
CONTRL FS-2YR 19 19 | 7| 3| 1| 7| 5| 5| 6| 4| 5| 6| 3| 4| 5| 6| 4| 5| 6| 5| 6| 7| 8| 6| 9| 3| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
ATROPHY | 2 3 | |
HYPERPLASIA,LYMPHOID | 2 | |
SPLEEN | A + + + + + + + + + + + + + + + + + + + + + + + + | |
CONGESTION | 2 | |
HEMATOPOIETIC CELL PROLIFERATION | 3 3 3 2 | |
HYPERPLASIA,LYMPHOID | 3 4 3 3 2 2 1 3 4 | |
INFARCT | | |
NECROSIS | 1| |
THYMUS | M + + M M + + + + + + + + + + M + + M + + + M + + | |
ATROPHY,CORTEX | 4 3 3 3 3 4 2 4 3 2 2 4 4| |
HYPERPLASIA,LYMPHOID,MEDULLA | 2 2 2 2 2 | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | A + + + + + + + + + + + + + + + M M + + + M A + + | |
HYPERPLASIA | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
SKIN | A + + + + + + + + + + + + + + + + + + + + + A + + | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | A + + + + + + + + + + + + + + + + + + + + + + + + | |
BONE,FEMUR | A + + + + + + + + + + + + + + + + + + + + + + + + | |
DEGENERATION,CARTILAGE | | |
FIBROUS OSTEODYSTROPHY | 1 1 2 2 2 2 2 1 1 1 1 | |
BONE,STERNUM | A + + M + + + + + + + + + + + + + + + + + M + + + | |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 2 2 3 1 2 2 1 1 2 3 1 2 2 1 3 | |
SKELETAL MUSCLE | A + + + A + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
MINERALIZATION,THALAMUS | 1 | |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 138
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:13.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2| 3| 6| 6|
| 7| 2| 3| 7| 9| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 8| 5| 5|
| 8| 6| 3| 3| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 3| 3| 3| 3| 7| 8| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| S R R|
| 5| 7| 8| 8| 9| 1| 1| 4| 4| 4| 7| 7| 7| 7| 0| 0| 0| 4| 4| 4| 4| 6| 6| 9| 9| U V I|
CONTRL FS-2YR 19 19 | 7| 3| 1| 7| 5| 5| 6| 4| 5| 6| 3| 4| 5| 6| 4| 5| 6| 5| 6| 7| 8| 6| 9| 3| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1| |
PERIPHERAL NERVE | A + + + A + + + + + + + + + + + + + + M + + + + + | |
DEMYELINATION | | |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + + + | |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DEGENERATION,AXON | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | A + + M + + + + + + + + + + + + + + + + + M M M + | |
LUNG | A + + + + + + + + + + + + + + + + + + + + + + + + | |
CONGESTION | 3 | |
EDEMA | 1 | |
HEMORRHAGE | 1 | |
INFILTRATION CELLULAR,HISTIOCYTIC | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 1 1 1 1 2 1 1 1| |
INFLAMMATION | 1 | |
PIGMENTATION,HEMOSIDERIN | | |
NOSE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CYTOPLASMIC ALTERATION,RESPIRATORY EPITHEL| 2 | |
IUM | | |
TRACHEA | A + + + + + + + + + + + + + + + + + + + + M + + + | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | A + + + A + + + + + + + + + + + + + + + + + A + + | |
HARDERIAN GLAND | A + + + A + + + + + + + + + + + + M + + + + M + + | |
ECTASIA | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 | |
LACRIMAL GLAND | A + + M + + + + + + + + + + + M + + + + + M M + + | |
ATROPHY | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 2 1 | |
ZYMBAL'S GLAND | A + M M + + + + + + + + + + M + + M + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 139
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:13.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2| 3| 6| 6|
| 7| 2| 3| 7| 9| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 8| 5| 5|
| 8| 6| 3| 3| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 3| 3| 3| 3| 7| 8| 6| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| S R R|
| 5| 7| 8| 8| 9| 1| 1| 4| 4| 4| 7| 7| 7| 7| 0| 0| 0| 4| 4| 4| 4| 6| 6| 9| 9| U V I|
CONTRL FS-2YR 19 19 | 7| 3| 1| 7| 5| 5| 6| 4| 5| 6| 3| 4| 5| 6| 4| 5| 6| 5| 6| 7| 8| 6| 9| 3| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM
KIDNEY | A + + + + + + + + + + + + + + + + + + + + + + + + | |
AMYLOID DEPOSITION,GLOMERULUS | 3 | |
CYST,RENAL TUBULE | 1 1 1 1 1 1 1| |
GLOMERULOSCLEROSIS | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 3 1 1 1 1 1 1 1 1 2 1 2 1 1 1 1 1| |
NEPHROPATHY | 1 | |
PIGMENTATION,RENAL TUBULE | | |
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + + + M A + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 3 1 1 1 1 1 1 1 1 1 1| |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 140
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:25.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 7| 7| 0| 2| 2| 2| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7| S R R|
| 9| 9| 2| 3| 3| 4| 0| 0| 0| 3| 3| 4| 5| 5| 5| 5| 9| 9| 9| 9| 5| 5| 5| U V I|
CONTRL FS-2YR 19 19 | 5| 6| 7| 8| 9| 0| 6| 7| 8| 8| 9| 0| 5| 6| 7| 8| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + + + + + + + + + + + + + M + | 45 |
HYPERKERATOSIS | | 2 2.0|
GALLBLADDER | A + + + + + M + M + + + + M + + + + + + + + + | 41 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 4 1.0|
INTESTINE LARGE | + + A + + + + + + + + + + + + + + + + + + + + | 44 |
INTESTINE LARGE,CECUM | + A A + + + + + + + + + + + + + + + + + + + + | 43 |
HYPERPLASIA,LYMPHOID | 3 3 | 4 2.5|
INTESTINE LARGE,COLON | + + A + + + + + + + + + + + + + + + + + + + + | 44 |
HYPERPLASIA,LYMPHOID | 2 | 1 2.0|
INTESTINE LARGE,RECTUM | + + A + + + + + + + + + + + + + + + + + + + + | 44 |
INTESTINE SMALL | A A A + + + + + + + + + + + + + + + + + + + + | 43 |
INTESTINE SMALL,DUODENUM | A A A + + + + + + + + + + + + + + + + + + + + | 43 |
INTESTINE SMALL,ILEUM | A A A + + + + M + + + + + + + + + + + + + + + | 40 |
INTESTINE SMALL,JEJUNUM | A A A + + + + + + + M + + + + + + + + + + + + | 41 |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BASOPHILIC FOCUS | X | 2 |
EOSINOPHILIC FOCUS | | 1 |
HEMATOPOIETIC CELL PROLIFERATION | 1 1 | 4 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 1 2 1 2 1 1 1 | 32 1.0|
INFLAMMATION | 1 | 1 1.0|
NECROSIS | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 | 34 1.0|
TENSION LIPOIDOSIS | X X X X X X X X X | 17 |
VACUOLIZATION CYTOPLASMIC | 3 2 3 1 1 1 1 1 1 1 1 1 1 1 | 27 1.2|
MESENTERY | | 1 |
NECROSIS,FAT | | 1 4.0|
PANCREAS | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
FOCAL CELLULAR CHANGE | 2 | 2 1.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 2 1 1 1 1 1 1 1 2 1 1 | 31 1.1|
INFLAMMATION | 1 | 1 1.0|
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ATROPHY | 3 4 1 | 4 2.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 2 1 2 2 2 2 1 1 1 1 2 2 1 2 2 | 38 1.3|
STOMACH | + + A + + + + + + + + + + + + + + + + + + + + | 45 |
STOMACH,FORESTOMACH | + + A + + + + + + + + + + + + + + + + + + + + | 45 |
HYPERKERATOSIS | 2 | 1 2.0|
STOMACH,GLANDULAR | + + A + + + + + + + + + + + + + + + + + + + + | 45 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 141
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:25.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 7| 7| 0| 2| 2| 2| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7| S R R|
| 9| 9| 2| 3| 3| 4| 0| 0| 0| 3| 3| 4| 5| 5| 5| 5| 9| 9| 9| 9| 5| 5| 5| U V I|
CONTRL FS-2YR 19 19 | 5| 6| 7| 8| 9| 0| 6| 7| 8| 8| 9| 0| 5| 6| 7| 8| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
CYST | 1 1 | 2 1.0|
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
INFLAMMATION | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + + + M + M + M + + + + + + + + | 41 |
BLOOD VESSEL,AORTA | + + + + + + + + + + M + M + M + + + + + + + + | 41 |
HEART | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
DEGENERATION,ARTERY | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
CYST | 3 | 1 3.0|
FOCAL CELLULAR CHANGE | 2 | 1 2.0|
HYPERPLASIA,SPINDLE CELL | 1 2 2 2 1 2 3 3 2 2 2 1 2 2 2 2 3 3 2 1 2 | 44 1.9|
VACUOLIZATION CYTOPLASMIC | 3 | 1 3.0|
ADRENAL GLAND,MEDULLA | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
FOCAL CELLULAR CHANGE | | 1 2.0|
VACUOLIZATION CYTOPLASMIC | 2 | 1 2.0|
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 2 1.0|
PARATHYROID GLAND | + + + + + + + + + + + + + + + + + + + + + M + | 44 |
CYST | 2 | 1 2.0|
ECTOPIC THYMUS | | 1 |
PITUITARY GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
ECTASIA | | 1 1.0|
HYPERPLASIA,PARS DISTALIS | 2 2 | 4 2.0|
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
CYST,FOLLICLE | 3 4 | 2 3.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 4 1.2|
ULTIMOBRANCHIAL CYST | 2 2 2 2 2 | 11 2.2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 142
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:25.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 7| 7| 0| 2| 2| 2| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7| S R R|
| 9| 9| 2| 3| 3| 4| 0| 0| 0| 3| 3| 4| 5| 5| 5| 5| 9| 9| 9| 9| 5| 5| 5| U V I|
CONTRL FS-2YR 19 19 | 5| 6| 7| 8| 9| 0| 6| 7| 8| 8| 9| 0| 5| 6| 7| 8| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
CLITORAL GLAND | M + + + + + + + + + M + + + + M + + + + + + + | 38 |
ATROPHY | 3 4 3 3 4 3 4 3 4 3 3 3 3 3 3 4 4 4 4 3 | 38 3.3|
INFLAMMATION | 1 | 1 1.0|
OVARY | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
ATROPHY | X X X X X X X X X X X X X X X X X X | 32 |
CYST | X X X X X X X X | 15 |
CYST,PERIOVARIAN TISSUE | X X X X X X X X X | 10 |
HEMATOCYST | X X | 4 |
HYPERPLASIA,ADENOMATOUS | 3 | 1 3.0|
HYPERPLASIA,TUBULAR | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 2 2.0|
OVOTESTIS | 2 | 1 2.0|
UTERUS | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ATROPHY | 3 3 | 6 2.8|
DILATATION | 4 | 2 3.0|
ECTASIA,VEIN | 4 | 1 4.0|
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 3 2 2 2 3 3 3 3 3 2 3 3 2 4 3 3 2 | 35 2.6|
METAPLASIA,SQUAMOUS | 2 | 1 2.0|
THROMBUS | 4 | 1 4.0|
VAGINA | + + + + + + + + + + + M + + + + + + + + + + + | 44 |
ATROPHY | 2 | 2 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 2 1.5|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HYPERPLASIA | 4 | 2 3.5|
HYPERPLASIA,LYMPHOID | | 1 2.0|
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HYPERPLASIA,LYMPHOID,AXILLARY | 4 | 1 4.0|
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ATROPHY | 3 4 | 4 3.0|
HEMORRHAGE | 4 | 1 4.0|
HYPERPLASIA,LYMPHOID | 2 2 2 4 | 7 2.7|
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 143
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:25.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 7| 7| 0| 2| 2| 2| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7| S R R|
| 9| 9| 2| 3| 3| 4| 0| 0| 0| 3| 3| 4| 5| 5| 5| 5| 9| 9| 9| 9| 5| 5| 5| U V I|
CONTRL FS-2YR 19 19 | 5| 6| 7| 8| 9| 0| 6| 7| 8| 8| 9| 0| 5| 6| 7| 8| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
ATROPHY | 3 4 3 3 | 6 3.0|
HYPERPLASIA,LYMPHOID | 2 2 | 3 2.0|
SPLEEN | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
CONGESTION | 2 2 2 3 | 5 2.2|
HEMATOPOIETIC CELL PROLIFERATION | 4 3 | 6 3.0|
HYPERPLASIA,LYMPHOID | 2 2 2 1 2 3 3 | 16 2.5|
INFARCT | 3 | 1 3.0|
NECROSIS | | 1 1.0|
THYMUS | M M M + + + M + + + M + + + + + + + + M + + + | 36 |
ATROPHY,CORTEX | 2 2 3 4 4 2 3 3 2 3 3 4 | 25 3.0|
HYPERPLASIA,LYMPHOID,MEDULLA | 2 2 3 3 1 | 10 2.1|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 43 |
HYPERPLASIA | 3 | 2 2.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 1 2.0|
SKIN | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
DEGENERATION,CARTILAGE | 4 | 1 4.0|
FIBROUS OSTEODYSTROPHY | 1 1 1 2 2 2 1 2 1 2 1 | 22 1.4|
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 1 1 2 2 2 2 1 2 2 1 3 3 1 1 3 3 2 2 3 1 | 35 1.8|
SKELETAL MUSCLE | M + + + + + + + + + + + + + + + + + + + + + + | 45 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
MINERALIZATION,THALAMUS | | 1 1.0|
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 144
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:25.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 7| 7| 0| 2| 2| 2| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7| S R R|
| 9| 9| 2| 3| 3| 4| 0| 0| 0| 3| 3| 4| 5| 5| 5| 5| 9| 9| 9| 9| 5| 5| 5| U V I|
CONTRL FS-2YR 19 19 | 5| 6| 7| 8| 9| 0| 6| 7| 8| 8| 9| 0| 5| 6| 7| 8| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 1 1 1 2 1 1 1 1 1 1 1 | 30 1.0|
PERIPHERAL NERVE | M + + + + + + + + + + + + + + + + + + + + + + | 44 |
DEMYELINATION | 1 | 1 1.0|
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
DEGENERATION,AXON | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + M + + + + + + + + + + + + + + + + + + + + | 42 |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
CONGESTION | | 1 3.0|
EDEMA | | 1 1.0|
HEMORRHAGE | | 1 1.0|
INFILTRATION CELLULAR,HISTIOCYTIC | 2 1 2 | 4 1.7|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 1 1 2 1 1 2 1 1 2 1 | 28 1.2|
INFLAMMATION | 1 2 2 | 4 1.5|
PIGMENTATION,HEMOSIDERIN | 4 | 1 4.0|
NOSE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
CYTOPLASMIC ALTERATION,RESPIRATORY EPITHEL| | 1 2.0|
IUM | | |
TRACHEA | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | A A A + + + + + + + + + + + + + + + + + + + + | 42 |
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 44 |
ECTASIA | 2 | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 2 1 | 21 1.0|
LACRIMAL GLAND | M + + + + + + + + + + M M M + + + + + + + M M | 37 |
ATROPHY | 3 2 2 2 | 5 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 2 2 2 1 1 1 1 2 | 21 1.2|
ZYMBAL'S GLAND | + M + + + + + + + + + + + + + + + + + + M + + | 41 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 145
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:25.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 5| 5| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 7| 7| 0| 2| 2| 2| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7| S R R|
| 9| 9| 2| 3| 3| 4| 0| 0| 0| 3| 3| 4| 5| 5| 5| 5| 9| 9| 9| 9| 5| 5| 5| U V I|
CONTRL FS-2YR 19 19 | 5| 6| 7| 8| 9| 0| 6| 7| 8| 8| 9| 0| 5| 6| 7| 8| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
AMYLOID DEPOSITION,GLOMERULUS | | 1 3.0|
CYST,RENAL TUBULE | 1 1 | 9 1.0|
GLOMERULOSCLEROSIS | 2 | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 3 2 2 1 2 2 1 1 3 1 2 1 2 | 37 1.3|
NEPHROPATHY | 1 | 2 1.0|
PIGMENTATION,RENAL TUBULE | 1 1 | 2 1.0|
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 2 1 2 1 1 1 1 1 1 1 1 1 2 1 2 1 1 | 38 1.1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 146
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:29.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 5| 5| 6| 6|
| 0| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 3| 9| 0| 6|
| 4| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 7| 3| 2| 8| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 6| 2| 2| 2| 2| 5| 5| 5| 8| 8| 8| 8| 0| 1| 1| 1| 5| 5| 5| 5| 7| 7| 8| 8| 0| U V I|
10MG FS-2YR 20 20 | 8| 0| 1| 2| 3| 1| 2| 3| 0| 1| 2| 3| 9| 0| 1| 2| 2| 3| 4| 5| 2| 4| 4| 5| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | A + M + M + | |
HYPERKERATOSIS | 2 | |
GALLBLADDER | A + + M + + | |
INTESTINE LARGE | A A + A + + | |
INTESTINE LARGE,CECUM | M A + A A + | |
INTESTINE LARGE,COLON | M A + A + + | |
INTESTINE LARGE,RECTUM | A A + A + + | |
INTESTINE SMALL | M A + A + + | |
INTESTINE SMALL,DUODENUM | M A + A A + | |
INTESTINE SMALL,ILEUM | M A + A A + | |
INTESTINE SMALL,JEJUNUM | M A + A + + | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | 2 | |
BASOPHILIC FOCUS | X | |
EOSINOPHILIC FOCUS | X | |
FIBROSIS | | |
HEMATOPOIETIC CELL PROLIFERATION | 1 | |
HYPERPLASIA,BILE DUCT | | |
HYPERPLASIA,KUPFFER CELL | 2| |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 2 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 | |
NECROSIS | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 | |
TENSION LIPOIDOSIS | X X X X X X X | |
VACUOLIZATION CYTOPLASMIC | 2 2 1 1 1 1 1 2 1 1 1 1 1 2 | |
PANCREAS | A A + A + A | |
ECTASIA,DUCT | | |
SALIVARY GLANDS | A + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1| |
STOMACH | M A + A + + | |
STOMACH,FORESTOMACH | M A + A + + | |
HYPERKERATOSIS | 2| |
HYPERPLASIA | 2 | |
STOMACH,GLANDULAR | M A + A + + | |
MINERALIZATION | | |
TONGUE | + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 147
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:29.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 5| 5| 6| 6|
| 0| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 3| 9| 0| 6|
| 4| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 7| 3| 2| 8| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 6| 2| 2| 2| 2| 5| 5| 5| 8| 8| 8| 8| 0| 1| 1| 1| 5| 5| 5| 5| 7| 7| 8| 8| 0| U V I|
10MG FS-2YR 20 20 | 8| 0| 1| 2| 3| 1| 2| 3| 0| 1| 2| 3| 9| 0| 1| 2| 2| 3| 4| 5| 2| 4| 4| 5| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + M M + M + | |
BLOOD VESSEL,AORTA | + M M + M + | |
HEART | + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | A A + + + + | |
ADRENAL GLAND,CORTEX | A A + + + + | |
HYPERPLASIA,SPINDLE CELL | 2 2 2 | |
ADRENAL GLAND,MEDULLA | A A + M + + | |
ISLETS, PANCREATIC | A A + A + A | |
PARATHYROID GLAND | A + M + M M | |
PITUITARY GLAND | A M M + M + | |
ANGIECTASIS | | |
HYPERPLASIA,PARS DISTALIS | | |
THYROID GLAND | A + M + M + | |
ULTIMOBRANCHIAL CYST | | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + + + + + | |
ATROPHY | 4 2 4 3| |
OVARY | A + + + + + + + + + + + + + | |
ATROPHY | X | |
CYST | X X X X X X X | |
CYST,PERIOVARIAN TISSUE | X X | |
HEMATOCYST | | |
INFLAMMATION | | |
UTERUS | A + + + + + + + + + + + + + + + + + + | |
ATROPHY | 4 4| |
DILATATION | | |
FIBROSIS | 1 1 | |
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 3 2 3 3 4 3 3 2 2 3 3 3 | |
INFLAMMATION | | |
VAGINA | A + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 148
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:29.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 5| 5| 6| 6|
| 0| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 3| 9| 0| 6|
| 4| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 7| 3| 2| 8| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 6| 2| 2| 2| 2| 5| 5| 5| 8| 8| 8| 8| 0| 1| 1| 1| 5| 5| 5| 5| 7| 7| 8| 8| 0| U V I|
10MG FS-2YR 20 20 | 8| 0| 1| 2| 3| 1| 2| 3| 0| 1| 2| 3| 9| 0| 1| 2| 2| 3| 4| 5| 2| 4| 4| 5| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
ATROPHY | 4 4| |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + | |
HYPERPLASIA | 3 | |
LYMPH NODE | + + + + + + | |
LYMPH NODE,MANDIBULAR | A + + + + + | |
HEMORRHAGE | 2 | |
HYPERPLASIA,LYMPHOID | 2 2 | |
LYMPH NODE,MESENTERIC | + A + A + + | |
INFLAMMATION | | |
SPLEEN | M + + + + + + A + + | |
ANGIECTASIS | | |
ATROPHY | 4 | |
HEMATOPOIETIC CELL PROLIFERATION | 1 4 | |
HYPERPLASIA,LYMPHOID | 1 | |
INFILTRATION CELLULAR,HISTIOCYTIC | 1 | |
NECROSIS | 1 | |
THYMUS | A + + M M + | |
ATROPHY,CORTEX | 4 4 | |
ECTOPIC PARATHYROID GLAND | X | |
HYPERPLASIA,LYMPHOID,MEDULLA | | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | A + + + + + M | |
HYPERPLASIA | 4 | |
METAPLASIA,SQUAMOUS | 4 | |
SKIN | A + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + | |
BONE,FEMUR | + + + + + + | |
BONE,STERNUM | + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 149
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:30.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 5| 5| 6| 6|
| 0| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 3| 9| 0| 6|
| 4| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 7| 3| 2| 8| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 6| 2| 2| 2| 2| 5| 5| 5| 8| 8| 8| 8| 0| 1| 1| 1| 5| 5| 5| 5| 7| 7| 8| 8| 0| U V I|
10MG FS-2YR 20 20 | 8| 0| 1| 2| 3| 1| 2| 3| 0| 1| 2| 3| 9| 0| 1| 2| 2| 3| 4| 5| 2| 4| 4| 5| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | | |
SKELETAL MUSCLE | + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + | |
BRAIN,CEREBRUM | + + + + + + | |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 | |
PERIPHERAL NERVE | + + + + + + | |
SPINAL CORD | + + + + + + | |
SPINAL CORD,THORACIC | + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | A + M M M + | |
LUNG | A + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | |
NOSE | + + + + + + | |
INFLAMMATION | 2| |
TRACHEA | A + M + M + | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | A A + A A A | |
HARDERIAN GLAND | + + + + + M | |
HYPERPLASIA | 4 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
LACRIMAL GLAND | A + + + M + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1| |
ZYMBAL'S GLAND | + + + M + M | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | A + + + + + | |
ACCUMULATION HYALINE DROPLET | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 150
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:30.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 5| 5| 6| 6|
| 0| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 3| 9| 0| 6|
| 4| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 7| 3| 2| 8| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 6| 2| 2| 2| 2| 5| 5| 5| 8| 8| 8| 8| 0| 1| 1| 1| 5| 5| 5| 5| 7| 7| 8| 8| 0| U V I|
10MG FS-2YR 20 20 | 8| 0| 1| 2| 3| 1| 2| 3| 0| 1| 2| 3| 9| 0| 1| 2| 2| 3| 4| 5| 2| 4| 4| 5| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM
CYST,RENAL TUBULE | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1| |
VACUOLIZATION CYTOPLASMIC,RENAL TUBULE | | |
URINARY BLADDER | A A + A + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1| |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 151
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:31.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 2| 3| 3| 3| 6| 2| 2| 2| 2| 3| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| S R R|
| 3| 3| 3| 3| 5| 6| 6| 8| 9| 0| 0| 0| 3| 5| 5| 5| 8| 8| 8| 6| 6| 6| 6| U V I|
10MG FS-2YR 20 20 | 1| 2| 3| 4| 9| 0| 1| 4| 9| 0| 1| 2| 5| 0| 1| 2| 4| 5| 6| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + | 5 |
HYPERKERATOSIS | | 1 2.0|
GALLBLADDER | + + | 6 |
INTESTINE LARGE | + + | 5 |
INTESTINE LARGE,CECUM | + + | 4 |
INTESTINE LARGE,COLON | + + | 5 |
INTESTINE LARGE,RECTUM | + + | 5 |
INTESTINE SMALL | + + + + | 7 |
INTESTINE SMALL,DUODENUM | + + + | 5 |
INTESTINE SMALL,ILEUM | + + | 4 |
INTESTINE SMALL,JEJUNUM | + + + + | 7 |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ANGIECTASIS | | 1 2.0|
BASOPHILIC FOCUS | X | 2 |
EOSINOPHILIC FOCUS | | 1 |
FIBROSIS | 1 | 1 1.0|
HEMATOPOIETIC CELL PROLIFERATION | 1 1 | 3 1.0|
HYPERPLASIA,BILE DUCT | 1 | 1 1.0|
HYPERPLASIA,KUPFFER CELL | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 3 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 | 36 1.1|
NECROSIS | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 | 36 1.0|
TENSION LIPOIDOSIS | X X X X X X X X X X X X X | 20 |
VACUOLIZATION CYTOPLASMIC | 1 1 1 1 1 1 2 2 2 2 1 1 3 2 2 2 1 2 1 3 1 2 | 36 1.4|
PANCREAS | + + + | 5 |
ECTASIA,DUCT | 4 | 1 4.0|
SALIVARY GLANDS | + + | 7 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 7 1.0|
STOMACH | + + | 5 |
STOMACH,FORESTOMACH | + + | 5 |
HYPERKERATOSIS | | 1 2.0|
HYPERPLASIA | | 1 2.0|
STOMACH,GLANDULAR | + + | 5 |
MINERALIZATION | 1 | 1 1.0|
TONGUE | + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 152
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:31.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 2| 3| 3| 3| 6| 2| 2| 2| 2| 3| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| S R R|
| 3| 3| 3| 3| 5| 6| 6| 8| 9| 0| 0| 0| 3| 5| 5| 5| 8| 8| 8| 6| 6| 6| 6| U V I|
10MG FS-2YR 20 20 | 1| 2| 3| 4| 9| 0| 1| 4| 9| 0| 1| 2| 5| 0| 1| 2| 4| 5| 6| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + | 5 |
BLOOD VESSEL,AORTA | + + | 5 |
HEART | + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + | 7 |
ADRENAL GLAND,CORTEX | + + | 6 |
HYPERPLASIA,SPINDLE CELL | 1 1 | 5 1.6|
ADRENAL GLAND,MEDULLA | + + + | 6 |
ISLETS, PANCREATIC | + + | 4 |
PARATHYROID GLAND | + M | 3 |
PITUITARY GLAND | + + | 4 |
ANGIECTASIS | 2 | 1 2.0|
HYPERPLASIA,PARS DISTALIS | 2 | 1 2.0|
THYROID GLAND | + + | 5 |
ULTIMOBRANCHIAL CYST | 2 3 | 2 2.5|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + M | 7 |
ATROPHY | 3 | 5 3.2|
OVARY | + + + + + + + + + | 22 |
ATROPHY | X X | 3 |
CYST | X X | 9 |
CYST,PERIOVARIAN TISSUE | X X X | 5 |
HEMATOCYST | X | 1 |
INFLAMMATION | 4 | 1 4.0|
UTERUS | + + + + + + + + + + + + | 30 |
ATROPHY | | 2 4.0|
DILATATION | 4 4 | 2 4.0|
FIBROSIS | | 2 1.0|
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 3 2 2 3 3 2 4 3 3 | 21 2.8|
INFLAMMATION | 4 | 1 4.0|
VAGINA | + + | 7 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 153
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:32.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 2| 3| 3| 3| 6| 2| 2| 2| 2| 3| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| S R R|
| 3| 3| 3| 3| 5| 6| 6| 8| 9| 0| 0| 0| 3| 5| 5| 5| 8| 8| 8| 6| 6| 6| 6| U V I|
10MG FS-2YR 20 20 | 1| 2| 3| 4| 9| 0| 1| 4| 9| 0| 1| 2| 5| 0| 1| 2| 4| 5| 6| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
ATROPHY | | 2 4.0|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + | 8 |
HYPERPLASIA | 2 | 2 2.5|
LYMPH NODE | + + + + + + + | 13 |
LYMPH NODE,MANDIBULAR | + + + | 8 |
HEMORRHAGE | | 1 2.0|
HYPERPLASIA,LYMPHOID | 2 | 3 2.0|
LYMPH NODE,MESENTERIC | + + + + + + | 10 |
INFLAMMATION | 2 | 1 2.0|
SPLEEN | + + + + + + + + + + | 18 |
ANGIECTASIS | 2 | 1 2.0|
ATROPHY | | 1 4.0|
HEMATOPOIETIC CELL PROLIFERATION | | 2 2.5|
HYPERPLASIA,LYMPHOID | 1 3 3 | 4 2.0|
INFILTRATION CELLULAR,HISTIOCYTIC | | 1 1.0|
NECROSIS | | 1 1.0|
THYMUS | + M | 4 |
ATROPHY,CORTEX | 3 | 3 3.6|
ECTOPIC PARATHYROID GLAND | | 1 |
HYPERPLASIA,LYMPHOID,MEDULLA | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + M | 6 |
HYPERPLASIA | | 1 4.0|
METAPLASIA,SQUAMOUS | | 1 4.0|
SKIN | + + | 7 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + | 8 |
BONE,FEMUR | + + | 8 |
BONE,STERNUM | + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 154
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:32.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 2| 3| 3| 3| 6| 2| 2| 2| 2| 3| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| S R R|
| 3| 3| 3| 3| 5| 6| 6| 8| 9| 0| 0| 0| 3| 5| 5| 5| 8| 8| 8| 6| 6| 6| 6| U V I|
10MG FS-2YR 20 20 | 1| 2| 3| 4| 9| 0| 1| 4| 9| 0| 1| 2| 5| 0| 1| 2| 4| 5| 6| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 2 | 1 2.0|
SKELETAL MUSCLE | + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + | 8 |
BRAIN,CEREBELLUM | + + | 8 |
BRAIN,CEREBRUM | + + | 8 |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 | 2 1.0|
PERIPHERAL NERVE | + + | 8 |
SPINAL CORD | + + | 8 |
SPINAL CORD,THORACIC | + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + | 4 |
LUNG | + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 4 1.0|
NOSE | + + | 8 |
INFLAMMATION | | 1 2.0|
TRACHEA | + M | 4 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + | 3 |
HARDERIAN GLAND | + + | 7 |
HYPERPLASIA | | 1 4.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
LACRIMAL GLAND | + + | 6 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 4 1.0|
ZYMBAL'S GLAND | + + | 6 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + | 8 |
ACCUMULATION HYALINE DROPLET | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 155
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:32.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 2| 3| 3| 3| 6| 2| 2| 2| 2| 3| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| S R R|
| 3| 3| 3| 3| 5| 6| 6| 8| 9| 0| 0| 0| 3| 5| 5| 5| 8| 8| 8| 6| 6| 6| 6| U V I|
10MG FS-2YR 20 20 | 1| 2| 3| 4| 9| 0| 1| 4| 9| 0| 1| 2| 5| 0| 1| 2| 4| 5| 6| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM
CYST,RENAL TUBULE | 1 3 | 3 1.6|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 6 1.0|
VACUOLIZATION CYTOPLASMIC,RENAL TUBULE | 2 | 1 2.0|
URINARY BLADDER | + + | 5 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 4 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 156
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:36.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 6| 6| 6| 7|
| 3| 6| 7| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 7| 6| 5| 8| 0|
| 9| 0| 7| 2| 2| 2| 2| 2| 2| 2| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 8| 3| 4| 5| 9|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| S R R|
| 5| 8| 9| 1| 1| 1| 4| 4| 4| 4| 7| 7| 0| 0| 0| 0| 4| 4| 4| 4| 8| 0| 0| 1| 1| U V I|
25MG FS-2YR 21 21 | 6| 4| 1| 2| 3| 4| 0| 1| 2| 3| 1| 2| 0| 1| 2| 3| 1| 2| 3| 4| 1| 6| 9| 5| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + | |
GALLBLADDER | + + + + + + + + | |
INTESTINE LARGE | + + + + + + + + | |
INTESTINE LARGE,CECUM | + + + + + + A + | |
INTESTINE LARGE,COLON | + + + + + + + + | |
INTESTINE LARGE,RECTUM | + + + + + + + + | |
INTESTINE SMALL | + + + + + + + + | |
INTESTINE SMALL,DUODENUM | + + + + + + + A | |
INFLAMMATION | 4 | |
INTESTINE SMALL,ILEUM | + + + + + + A + | |
INTESTINE SMALL,JEJUNUM | + + + + + + A + | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BASOPHILIC FOCUS | X | |
CLEAR CELL FOCUS | X | |
EOSINOPHILIC FOCUS | X | |
HEMATOPOIETIC CELL PROLIFERATION | 2 1 1 1 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 3 1 3 1 1 1 1 2 1 1 1 3 1 1 1 1 1 2 1 | |
NECROSIS | 1 1 1 1 1 1 1 1 1 1 1 1 1 | |
NECROSIS,COAGULATIVE | 4 | |
TENSION LIPOIDOSIS | X X X X | |
VACUOLIZATION CYTOPLASMIC | 1 1 2 2 2 1 2 2 1 1 1 1 1 1 1 2| |
PANCREAS | + + + + + + + + | |
ATROPHY | 3 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1| |
SALIVARY GLANDS | + + + + + + + + | |
ATROPHY | 3 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 2 1 1| |
STOMACH | + + + + + + + + | |
STOMACH,FORESTOMACH | + + + + + + + + | |
HYPERKERATOSIS | 2 | |
STOMACH,GLANDULAR | + + + + + + + + | |
CYST | 1| |
TONGUE | + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 157
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:36.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 6| 6| 6| 7|
| 3| 6| 7| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 7| 6| 5| 8| 0|
| 9| 0| 7| 2| 2| 2| 2| 2| 2| 2| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 8| 3| 4| 5| 9|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| S R R|
| 5| 8| 9| 1| 1| 1| 4| 4| 4| 4| 7| 7| 0| 0| 0| 0| 4| 4| 4| 4| 8| 0| 0| 1| 1| U V I|
25MG FS-2YR 21 21 | 6| 4| 1| 2| 3| 4| 0| 1| 2| 3| 1| 2| 0| 1| 2| 3| 1| 2| 3| 4| 1| 6| 9| 5| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | M M + + + + + + | |
BLOOD VESSEL,AORTA | M M + + + + + + | |
HEART | + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + | |
ACCESSORY ADRENAL CORTICAL NODULE | X | |
ADRENAL GLAND,CORTEX | + + + + + + + + | |
HYPERPLASIA,SPINDLE CELL | 2 1 1 2 1 1 2| |
ADRENAL GLAND,MEDULLA | + + + + + + + + | |
ISLETS, PANCREATIC | + + + + + + + + | |
PARATHYROID GLAND | + M + M + + M M | |
PITUITARY GLAND | + + + + + + M + M | |
CYST | 1 | |
THYROID GLAND | + + + + + + M + | |
DEPLETION SECRETORY | 2 | |
HYPERPLASIA,FOLLICULAR CELL | 4| |
INFLAMMATION | | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + M + M + + + + | |
ATROPHY | 4 3 4 4 4| |
OVARY | + + + + + + + + + + + + + + + M + | |
AMYLOID DEPOSITION | 3 | |
ATROPHY | X X X X | |
CYST | X X X X X X X X | |
CYST,PERIOVARIAN TISSUE | X X X | |
HEMORRHAGE | 3 | |
UTERUS | + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | | |
ATROPHY | 3 4 4 | |
DILATATION | 2 | |
FIBROSIS | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 158
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:36.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 6| 6| 6| 7|
| 3| 6| 7| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 7| 6| 5| 8| 0|
| 9| 0| 7| 2| 2| 2| 2| 2| 2| 2| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 8| 3| 4| 5| 9|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| S R R|
| 5| 8| 9| 1| 1| 1| 4| 4| 4| 4| 7| 7| 0| 0| 0| 0| 4| 4| 4| 4| 8| 0| 0| 1| 1| U V I|
25MG FS-2YR 21 21 | 6| 4| 1| 2| 3| 4| 0| 1| 2| 3| 1| 2| 0| 1| 2| 3| 1| 2| 3| 4| 1| 6| 9| 5| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
HEMORRHAGE | | |
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 3 4 2 3 3 2 3 2 2 2| |
VAGINA | + + + + + + + + | |
AMYLOID DEPOSITION | 2 | |
ATROPHY | 3 2 | |
DYSPLASIA | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + | |
CONGESTION | 2 | |
HYPERPLASIA | 3 4 3| |
MYELOFIBROSIS | 4 | |
LYMPH NODE | + + + + + + + A + | |
LYMPH NODE,MANDIBULAR | + + + + + + A + | |
ATROPHY | 4 | |
HEMORRHAGE | | |
HYPERPLASIA,LYMPHOID | 2 | |
POLYARTERITIS | | |
LYMPH NODE,MESENTERIC | + + + M + + A + | |
ATROPHY | 4 4 | |
HEMATOPOIETIC CELL PROLIFERATION | 4 | |
HEMORRHAGE | | |
SPLEEN | + + + + + + + + + + | |
AMYLOID DEPOSITION | 1 | |
ATROPHY | 2 2 2 | |
HEMATOPOIETIC CELL PROLIFERATION | 3 3 4 4 | |
HYPERPLASIA,LYMPHOID | 3 1 | |
NECROSIS | 2 | |
POLYARTERITIS | 2 | |
THYMUS | M M + + + + + M M + | |
ATROPHY,CORTEX | 4 3 3| |
HYPERPLASIA,LYMPHOID,MEDULLA | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 159
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:37.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 6| 6| 6| 7|
| 3| 6| 7| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 7| 6| 5| 8| 0|
| 9| 0| 7| 2| 2| 2| 2| 2| 2| 2| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 8| 3| 4| 5| 9|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| S R R|
| 5| 8| 9| 1| 1| 1| 4| 4| 4| 4| 7| 7| 0| 0| 0| 0| 4| 4| 4| 4| 8| 0| 0| 1| 1| U V I|
25MG FS-2YR 21 21 | 6| 4| 1| 2| 3| 4| 0| 1| 2| 3| 1| 2| 0| 1| 2| 3| 1| 2| 3| 4| 1| 6| 9| 5| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + + + + + + | |
LACTATION | 2 | |
SKIN | + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + | |
BONE,FEMUR | + + + + + + + + | |
BONE,STERNUM | + + + + + + + + | |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 2 2 1| |
SKELETAL MUSCLE | + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + + | |
BRAIN,CEREBRUM | + + + + + + + + | |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 2 | |
PERIPHERAL NERVE | + + + + + + + + | |
SPINAL CORD | + + + + + + M + | |
SPINAL CORD,THORACIC | + + + + + + M + | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + M + + + + + | |
LUNG | + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2| |
METAPLASIA,OSSEOUS | X | |
NOSE | + + + + + + + + | |
TRACHEA | + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + A A + + + A A | |
CATARACT | | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 160
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:37.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 6| 6| 6| 7|
| 3| 6| 7| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 7| 6| 5| 8| 0|
| 9| 0| 7| 2| 2| 2| 2| 2| 2| 2| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 8| 3| 4| 5| 9|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| S R R|
| 5| 8| 9| 1| 1| 1| 4| 4| 4| 4| 7| 7| 0| 0| 0| 0| 4| 4| 4| 4| 8| 0| 0| 1| 1| U V I|
25MG FS-2YR 21 21 | 6| 4| 1| 2| 3| 4| 0| 1| 2| 3| 1| 2| 0| 1| 2| 3| 1| 2| 3| 4| 1| 6| 9| 5| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
HARDERIAN GLAND | + + + + + + + + | |
ATROPHY | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | |
LACRIMAL GLAND | + M + + + M + + | |
CYTOPLASMIC ALTERATION | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1| |
ZYMBAL'S GLAND | M + + + + M + + | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + | |
ACCUMULATION HYALINE DROPLET | | |
AMYLOID DEPOSITION,GLOMERULUS | 4 | |
CYST,RENAL TUBULE | 1 1 | |
HEMATOPOIETIC CELL PROLIFERATION | 1 | |
HYDRONEPHROSIS | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 1 1 1| |
VACUOLIZATION CYTOPLASMIC,RENAL TUBULE | 2 | |
URINARY BLADDER | + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 161
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:38.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 3| 3| 3| 3| 4| 2| 2| 2| 3| 3| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| S R R|
| 3| 3| 3| 6| 6| 6| 6| 8| 0| 0| 0| 3| 3| 5| 5| 8| 8| 8| 9| 5| 5| 5| 5| U V I|
25MG FS-2YR 21 21 | 5| 6| 7| 2| 3| 4| 5| 6| 3| 4| 5| 6| 7| 3| 4| 7| 8| 9| 0| 1| 2| 3| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + | 10 |
GALLBLADDER | + M | 9 |
INTESTINE LARGE | + A | 9 |
INTESTINE LARGE,CECUM | + A | 8 |
INTESTINE LARGE,COLON | + A | 9 |
INTESTINE LARGE,RECTUM | + A | 9 |
INTESTINE SMALL | + + A | 10 |
INTESTINE SMALL,DUODENUM | + + A | 9 |
INFLAMMATION | | 1 4.0|
INTESTINE SMALL,ILEUM | M A | 7 |
INTESTINE SMALL,JEJUNUM | + A | 8 |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BASOPHILIC FOCUS | X X | 3 |
CLEAR CELL FOCUS | | 1 |
EOSINOPHILIC FOCUS | | 1 |
HEMATOPOIETIC CELL PROLIFERATION | 1 1 1 | 9 1.1|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 2 1 1 1 1 1 2 1 1 1 1 1 1 | 38 1.2|
NECROSIS | 1 1 1 2 1 1 2 1 1 1 1 1 1 1 1 1 1 2 | 31 1.0|
NECROSIS,COAGULATIVE | | 1 4.0|
TENSION LIPOIDOSIS | X X X X X X | 10 |
VACUOLIZATION CYTOPLASMIC | 1 2 1 1 1 2 1 1 1 1 1 2 2 3 3 3 3 1 2 3 | 36 1.5|
PANCREAS | + + | 10 |
ATROPHY | | 1 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 6 1.0|
SALIVARY GLANDS | + + | 10 |
ATROPHY | | 1 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 6 1.3|
STOMACH | + A | 9 |
STOMACH,FORESTOMACH | + A | 9 |
HYPERKERATOSIS | | 1 2.0|
STOMACH,GLANDULAR | + A | 9 |
CYST | | 1 1.0|
TONGUE | + + | 10 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 162
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:39.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 3| 3| 3| 3| 4| 2| 2| 2| 3| 3| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| S R R|
| 3| 3| 3| 6| 6| 6| 6| 8| 0| 0| 0| 3| 3| 5| 5| 8| 8| 8| 9| 5| 5| 5| 5| U V I|
25MG FS-2YR 21 21 | 5| 6| 7| 2| 3| 4| 5| 6| 3| 4| 5| 6| 7| 3| 4| 7| 8| 9| 0| 1| 2| 3| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + | 8 |
BLOOD VESSEL,AORTA | + + | 8 |
HEART | + + | 10 |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + | 10 |
ACCESSORY ADRENAL CORTICAL NODULE | | 1 |
ADRENAL GLAND,CORTEX | + + | 10 |
HYPERPLASIA,SPINDLE CELL | 2 2 | 9 1.5|
ADRENAL GLAND,MEDULLA | + + | 10 |
ISLETS, PANCREATIC | + + + | 11 |
PARATHYROID GLAND | + M | 5 |
PITUITARY GLAND | + + | 9 |
CYST | | 1 1.0|
THYROID GLAND | + + | 9 |
DEPLETION SECRETORY | | 1 2.0|
HYPERPLASIA,FOLLICULAR CELL | | 1 4.0|
INFLAMMATION | 1 | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + | 8 |
ATROPHY | 4 3 | 7 3.7|
OVARY | + + + + + + + + + + + + + + | 30 |
AMYLOID DEPOSITION | | 1 3.0|
ATROPHY | | 4 |
CYST | X X X X X X X X | 16 |
CYST,PERIOVARIAN TISSUE | X X X X X X | 9 |
HEMORRHAGE | | 1 3.0|
UTERUS | + + + + + + + + + + + + + + + + + + | 35 |
ANGIECTASIS | 4 | 1 4.0|
ATROPHY | 4 | 4 3.7|
DILATATION | 4 | 2 3.0|
FIBROSIS | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 163
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:39.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 3| 3| 3| 3| 4| 2| 2| 2| 3| 3| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| S R R|
| 3| 3| 3| 6| 6| 6| 6| 8| 0| 0| 0| 3| 3| 5| 5| 8| 8| 8| 9| 5| 5| 5| 5| U V I|
25MG FS-2YR 21 21 | 5| 6| 7| 2| 3| 4| 5| 6| 3| 4| 5| 6| 7| 3| 4| 7| 8| 9| 0| 1| 2| 3| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
HEMORRHAGE | 4 | 1 4.0|
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 3 3 3 4 4 3 2 2 2 2 3 3 | 24 2.6|
VAGINA | + + | 10 |
AMYLOID DEPOSITION | | 1 2.0|
ATROPHY | | 2 2.5|
DYSPLASIA | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + | 10 |
CONGESTION | | 1 2.0|
HYPERPLASIA | 3 | 4 3.2|
MYELOFIBROSIS | | 1 4.0|
LYMPH NODE | + + + | 11 |
LYMPH NODE,MANDIBULAR | + + | 9 |
ATROPHY | | 1 4.0|
HEMORRHAGE | 1 | 1 1.0|
HYPERPLASIA,LYMPHOID | 2 | 2 2.0|
POLYARTERITIS | 3 | 1 3.0|
LYMPH NODE,MESENTERIC | + + | 8 |
ATROPHY | | 2 4.0|
HEMATOPOIETIC CELL PROLIFERATION | | 1 4.0|
HEMORRHAGE | 2 | 1 2.0|
SPLEEN | + + + + + + + | 17 |
AMYLOID DEPOSITION | | 1 1.0|
ATROPHY | 3 2 | 5 2.2|
HEMATOPOIETIC CELL PROLIFERATION | 2 4 2 3 | 8 3.1|
HYPERPLASIA,LYMPHOID | 2 3 2 | 5 2.2|
NECROSIS | | 1 2.0|
POLYARTERITIS | | 1 2.0|
THYMUS | M + | 7 |
ATROPHY,CORTEX | 4 | 4 3.5|
HYPERPLASIA,LYMPHOID,MEDULLA | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 164
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:39.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 3| 3| 3| 3| 4| 2| 2| 2| 3| 3| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| S R R|
| 3| 3| 3| 6| 6| 6| 6| 8| 0| 0| 0| 3| 3| 5| 5| 8| 8| 8| 9| 5| 5| 5| 5| U V I|
25MG FS-2YR 21 21 | 5| 6| 7| 2| 3| 4| 5| 6| 3| 4| 5| 6| 7| 3| 4| 7| 8| 9| 0| 1| 2| 3| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + M | 11 |
LACTATION | | 1 2.0|
SKIN | + + | 10 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + | 10 |
BONE,FEMUR | + + | 10 |
BONE,STERNUM | + + | 10 |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | | 3 1.6|
SKELETAL MUSCLE | + + | 10 |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + | 10 |
BRAIN,CEREBELLUM | + + | 10 |
BRAIN,CEREBRUM | + + | 10 |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 | 3 1.3|
PERIPHERAL NERVE | + + | 10 |
SPINAL CORD | + + | 9 |
SPINAL CORD,THORACIC | + + | 9 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + | 9 |
LUNG | + + | 11 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 4 1.2|
METAPLASIA,OSSEOUS | | 1 |
NOSE | + + | 10 |
TRACHEA | + + | 10 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | A + A | 5 |
CATARACT | 4 | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 165
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:39.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 3| 3| 3| 3| 4| 2| 2| 2| 3| 3| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| S R R|
| 3| 3| 3| 6| 6| 6| 6| 8| 0| 0| 0| 3| 3| 5| 5| 8| 8| 8| 9| 5| 5| 5| 5| U V I|
25MG FS-2YR 21 21 | 5| 6| 7| 2| 3| 4| 5| 6| 3| 4| 5| 6| 7| 3| 4| 7| 8| 9| 0| 1| 2| 3| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
HARDERIAN GLAND | + + | 10 |
ATROPHY | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 2 1.0|
LACRIMAL GLAND | M + | 7 |
CYTOPLASMIC ALTERATION | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 6 1.0|
ZYMBAL'S GLAND | + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + | 10 |
ACCUMULATION HYALINE DROPLET | 2 2 | 2 2.0|
AMYLOID DEPOSITION,GLOMERULUS | | 1 4.0|
CYST,RENAL TUBULE | | 2 1.0|
HEMATOPOIETIC CELL PROLIFERATION | | 1 1.0|
HYDRONEPHROSIS | 1 | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 9 1.1|
VACUOLIZATION CYTOPLASMIC,RENAL TUBULE | | 1 2.0|
URINARY BLADDER | + + | 10 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 5 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 166
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:52.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 3| 4| 6| 7| 7|
| 1| 7| 7| 1| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 8| 8| 9| 4| 4|
| 7| 5| 6| 5| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 7| 4| 4| 3| 3| 3| 1| 4| 7| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| S R R|
| 7| 8| 9| 0| 1| 1| 1| 4| 4| 4| 5| 7| 7| 7| 9| 0| 0| 4| 5| 5| 6| 7| 2| 4| 4| U V I|
50MG FS-2YR 22 22 | 2| 9| 0| 3| 7| 8| 9| 7| 8| 9| 0| 7| 8| 9| 9| 7| 8| 9| 0| 1| 8| 1| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | M + + A + + + + + + + + + + + + + + + + + + + + + | |
GALLBLADDER | + + + M + + + + + + + + + M + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 | |
INFLAMMATION | 1 | |
INTESTINE LARGE | A + + A + + + + + + + + + + A + + + + + + + + + + | |
INTESTINE LARGE,CECUM | A + + A + + + + + + + + + + A + + + + + + + + + + | |
INTESTINE LARGE,COLON | A + + A + + + + + + + + + + A + + + + + + + + + + | |
INFLAMMATION | 3 | |
INTESTINE LARGE,RECTUM | A + + A + + + + + + + + + + A + + + + + + + + + + | |
INTESTINE SMALL | A + + A + + + + + + + + + + A + + + + + + + + + + | |
INTESTINE SMALL,DUODENUM | A + + A + + + + + + + + + + A + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
INTESTINE SMALL,ILEUM | A + + A + + + + + + + + + + A + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | 2 2 2 | |
INTESTINE SMALL,JEJUNUM | A + + A + + + + + + + + + + A + + + + + + + + + + | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | 2 4 | |
BASOPHILIC FOCUS | | |
ECTASIA,VEIN | 2 | |
HEMATOPOIETIC CELL PROLIFERATION | 3 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 2 2 1 2 1 2 1 1 2 1 1| |
MINERALIZATION | 2 | |
NECROSIS | 1 1 1 1 1 1 1 1 2 3 1 1 1 1| |
REGENERATION | 3 | |
TENSION LIPOIDOSIS | X X X X X | |
THROMBUS | | |
VACUOLIZATION CYTOPLASMIC | 2 2 2 3 2 1 2 1 2 1 1 1 1 1| |
MESENTERY | + | |
NECROSIS,FAT | 4 | |
PANCREAS | + + + A + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 1 1| |
FOCAL CELLULAR CHANGE | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1| |
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 2 2 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1| |
STOMACH | + + + A + + + + + + + + M + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 167
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:53.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 3| 4| 6| 7| 7|
| 1| 7| 7| 1| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 8| 8| 9| 4| 4|
| 7| 5| 6| 5| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 7| 4| 4| 3| 3| 3| 1| 4| 7| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| S R R|
| 7| 8| 9| 0| 1| 1| 1| 4| 4| 4| 5| 7| 7| 7| 9| 0| 0| 4| 5| 5| 6| 7| 2| 4| 4| U V I|
50MG FS-2YR 22 22 | 2| 9| 0| 3| 7| 8| 9| 7| 8| 9| 0| 7| 8| 9| 9| 7| 8| 9| 0| 1| 8| 1| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
STOMACH,FORESTOMACH | + + + A + + + + + + + + M + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
STOMACH,GLANDULAR | + + + A + + + + + + + + M + + + + + + + + + + + + | |
CYST | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | M M + + + + + + + + + + + + + + + + + + + + + + + | |
BLOOD VESSEL,AORTA | M M + + + + + + + + + + + + + + + + + + + + + + + | |
HEART | + + + + + + + + + + + + + + + + + + + + + + + + + | |
FIBROSIS | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | | |
HYPERPLASIA,SPINDLE CELL | 2 1 1 1 3 1 1 1 1 1 1 2 1 1 1 1 1 2 2 3 3 1| |
ADRENAL GLAND,MEDULLA | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ISLETS, PANCREATIC | + + + A + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | | |
PARATHYROID GLAND | M + + A + + + + + + + + + M + + + + + + + + + + + | |
PITUITARY GLAND | M + + + + + + + + + + + + + + + + M + + + M + + M | |
ANGIECTASIS | | |
HYPERPLASIA,PARS DISTALIS | 4 | |
THYROID GLAND | + + + A + + + + + + + + + + + + + + + + + + + + + | |
CYST,FOLLICLE | | |
GOITER ADENOMATOUS | 2 | |
ULTIMOBRANCHIAL CYST | 2 2 2 2 2 2 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 168
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:53.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 3| 4| 6| 7| 7|
| 1| 7| 7| 1| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 8| 8| 9| 4| 4|
| 7| 5| 6| 5| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 7| 4| 4| 3| 3| 3| 1| 4| 7| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| S R R|
| 7| 8| 9| 0| 1| 1| 1| 4| 4| 4| 5| 7| 7| 7| 9| 0| 0| 4| 5| 5| 6| 7| 2| 4| 4| U V I|
50MG FS-2YR 22 22 | 2| 9| 0| 3| 7| 8| 9| 7| 8| 9| 0| 7| 8| 9| 9| 7| 8| 9| 0| 1| 8| 1| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
CLITORAL GLAND | + + + + M + + + M + + + + + + + + M M + M M + M + | |
ATROPHY | 4 4 2 2 1 2 2 1 2 2 3 2 2 2 4 2| |
OVARY | + + + + + + + + M + + + + + + + + + M + + + + + + | |
ANGIECTASIS | 3 4| |
ATROPHY | X X X X X X X X X X X X X X | |
CONGESTION | 1 | |
CYST | X X X X | |
CYST,PERIOVARIAN TISSUE | X X | |
HEMATOCYST | X X | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
MINERALIZATION | 1 | |
OVOTESTIS | | |
UTERUS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ADENOMYOSIS | | |
ATROPHY | 4 3 4 | |
DILATATION | 1 2 | |
HYPERPLASIA,ATYPICAL | | |
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 3 2 3 3 3 3 1 2 2 1 2 2 3 2 4 2 1 3| |
HYPERTROPHY,MYOMETRIUM | | |
VAGINA | + M + A + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 3 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | | |
MYELOFIBROSIS | 4 | |
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | 3 | |
HYPERPLASIA,LYMPHOID,RENAL | | |
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HEMORRHAGE | 1 | |
HYPERPLASIA,LYMPHOID | 2 2 1 1 2 | |
INFILTRATION CELLULAR,HISTIOCYTIC | | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 169
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:53.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 3| 4| 6| 7| 7|
| 1| 7| 7| 1| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 8| 8| 9| 4| 4|
| 7| 5| 6| 5| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 7| 4| 4| 3| 3| 3| 1| 4| 7| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| S R R|
| 7| 8| 9| 0| 1| 1| 1| 4| 4| 4| 5| 7| 7| 7| 9| 0| 0| 4| 5| 5| 6| 7| 2| 4| 4| U V I|
50MG FS-2YR 22 22 | 2| 9| 0| 3| 7| 8| 9| 7| 8| 9| 0| 7| 8| 9| 9| 7| 8| 9| 0| 1| 8| 1| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
LYMPH NODE,MESENTERIC | M + + A + + + + + + + + + + + + + + + + + + + M + | |
HYPERPLASIA,LYMPHOID | 1 1 | |
INFILTRATION CELLULAR,HISTIOCYTIC | | |
SPLEEN | + + + A + + + + + + + + + + + + + + + + + + + + + | |
HEMATOCYST | | |
HEMATOPOIETIC CELL PROLIFERATION | 3 3 3 4 | |
HYPERPLASIA,LYMPHOID | 3 2 1 1 1 3 3 3 1 2 1 2 2 | |
NECROSIS | 1 | |
THYMUS | M M + + + + + M + + + + + + + + + + + + M M M + + | |
ATROPHY,CORTEX | 2 4 3 3 3 3 3 3 3 4 3 3 2 3 4 4| |
HYPERPLASIA,LYMPHOID,MEDULLA | 2 2 2 1 2 3 2 3 2 | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
LACTATION | 1 1 1 3 1 1 1 1 | |
SKIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY,TURBINATE | 1 1 1 1 | |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY | 1 1 1 | |
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 2 2 2 1 3 1 1 1 1 1 1 1 1 1 1 2 2 1| |
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + M + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYDROCEPHALUS | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 170
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:53.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 3| 4| 6| 7| 7|
| 1| 7| 7| 1| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 8| 8| 9| 4| 4|
| 7| 5| 6| 5| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 7| 4| 4| 3| 3| 3| 1| 4| 7| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| S R R|
| 7| 8| 9| 0| 1| 1| 1| 4| 4| 4| 5| 7| 7| 7| 9| 0| 0| 4| 5| 5| 6| 7| 2| 4| 4| U V I|
50MG FS-2YR 22 22 | 2| 9| 0| 3| 7| 8| 9| 7| 8| 9| 0| 7| 8| 9| 9| 7| 8| 9| 0| 1| 8| 1| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
MINERALIZATION,MULTIFOCAL,THALAMUS | 2 1 1 1 1 1 1 1 2 1 1 1 1| |
PERIPHERAL NERVE | + + M + + + + + + + + + + + + + + + M + + + + + + | |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + + + | |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | M + + A + + + + + + + + + + + + + + + + M + + + + | |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CRYSTALS | 1 | |
HYPERPLASIA,ALVEOLAR EPITHELIUM | 1 | |
INFILTRATION CELLULAR,HISTIOCYTIC | 2 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 1 1 2 1 1 1 1 1 1 1 1 2 2 3 2 1 1 1 1 1| |
INFLAMMATION | | |
THROMBUS | | |
NOSE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
TRACHEA | + + + A + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + A A + + + + + + + + + + A + + + + + + + + + + | |
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 | |
LACRIMAL GLAND | + + + + + + + + + + + + + + + + + + M + + + + + + | |
FOCAL CELLULAR CHANGE | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 1 2 1 1 1 1 1 2 1 1 1 1 1 1| |
ZYMBAL'S GLAND | + + + M + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AMYLOID DEPOSITION,GLOMERULUS | 4 | |
CYST,RENAL TUBULE | 1 1 1 2 | |
EDEMA | | |
GLOMERULOSCLEROSIS | 2 1 1 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 171
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:38:53.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 3| 4| 6| 7| 7|
| 1| 7| 7| 1| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 8| 8| 9| 4| 4|
| 7| 5| 6| 5| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 7| 4| 4| 3| 3| 3| 1| 4| 7| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| S R R|
| 7| 8| 9| 0| 1| 1| 1| 4| 4| 4| 5| 7| 7| 7| 9| 0| 0| 4| 5| 5| 6| 7| 2| 4| 4| U V I|
50MG FS-2YR 22 22 | 2| 9| 0| 3| 7| 8| 9| 7| 8| 9| 0| 7| 8| 9| 9| 7| 8| 9| 0| 1| 8| 1| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM
INFARCT | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 3 2 2 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1| |
PIGMENTATION,RENAL TUBULE | 1 | |
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1| |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 172
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:05.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| S R R|
| 4| 4| 6| 6| 6| 0| 1| 1| 1| 4| 4| 5| 6| 6| 6| 9| 9| 9| 9| 5| 5| 6| 6| U V I|
50MG FS-2YR 22 22 | 3| 4| 6| 7| 8| 9| 0| 1| 2| 1| 2| 9| 0| 1| 2| 5| 6| 7| 8| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + M + + + + + + + + + + + + + + | 45 |
GALLBLADDER | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 3 1.0|
INFLAMMATION | 1 | 2 1.0|
INTESTINE LARGE | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
INTESTINE LARGE,CECUM | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
INTESTINE LARGE,COLON | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
INFLAMMATION | | 1 3.0|
INTESTINE LARGE,RECTUM | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
INTESTINE SMALL | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
INTESTINE SMALL,DUODENUM | + + + + + + + + + + + + + + + + + + + M + + + | 44 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
INTESTINE SMALL,ILEUM | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
HYPERPLASIA,LYMPHOID | | 3 2.0|
INTESTINE SMALL,JEJUNUM | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ANGIECTASIS | 3 | 3 3.0|
BASOPHILIC FOCUS | X X X | 3 |
ECTASIA,VEIN | | 1 2.0|
HEMATOPOIETIC CELL PROLIFERATION | 1 2 1 1 | 7 1.4|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 1 1 3 1 1 1 1 1 1 1 1 1 | 37 1.2|
MINERALIZATION | | 1 2.0|
NECROSIS | 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 | 33 1.1|
REGENERATION | | 1 3.0|
TENSION LIPOIDOSIS | X X X X X X | 11 |
THROMBUS | 3 | 1 3.0|
VACUOLIZATION CYTOPLASMIC | 1 2 1 1 1 3 2 1 2 | 23 1.5|
MESENTERY | | 1 |
NECROSIS,FAT | | 1 4.0|
PANCREAS | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ATROPHY | | 2 1.0|
FOCAL CELLULAR CHANGE | 1 | 2 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 | 30 1.0|
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 2 2 1 1 1 1 1 2 1 1 1 1 1 1 1 2 2 1 1 | 45 1.2|
STOMACH | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 173
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:05.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| S R R|
| 4| 4| 6| 6| 6| 0| 1| 1| 1| 4| 4| 5| 6| 6| 6| 9| 9| 9| 9| 5| 5| 6| 6| U V I|
50MG FS-2YR 22 22 | 3| 4| 6| 7| 8| 9| 0| 1| 2| 1| 2| 9| 0| 1| 2| 5| 6| 7| 8| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
STOMACH,FORESTOMACH | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
STOMACH,GLANDULAR | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
CYST | | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
BLOOD VESSEL,AORTA | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
HEART | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
FIBROSIS | | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HYPERPLASIA | 1 | 1 1.0|
HYPERPLASIA,SPINDLE CELL | 2 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 2 1 1 | 44 1.2|
ADRENAL GLAND,MEDULLA | + + + + + + + + + + + + + + + + + + + + + + M | 47 |
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HYPERPLASIA | 1 | 1 1.0|
PARATHYROID GLAND | + + + + + + + M + + + + + + + + + M + + + + + | 43 |
PITUITARY GLAND | + + + + + + + + + + + M + + + + + + + + + + + | 43 |
ANGIECTASIS | 1 | 1 1.0|
HYPERPLASIA,PARS DISTALIS | 1 3 | 3 2.6|
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
CYST,FOLLICLE | 1 1 | 2 1.0|
GOITER ADENOMATOUS | | 1 2.0|
ULTIMOBRANCHIAL CYST | 3 2 2 3 2 3 3 2 | 14 2.2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 174
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:05.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| S R R|
| 4| 4| 6| 6| 6| 0| 1| 1| 1| 4| 4| 5| 6| 6| 6| 9| 9| 9| 9| 5| 5| 6| 6| U V I|
50MG FS-2YR 22 22 | 3| 4| 6| 7| 8| 9| 0| 1| 2| 1| 2| 9| 0| 1| 2| 5| 6| 7| 8| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
CLITORAL GLAND | + + + + + + + M + + + + + M + + M M M M + + + | 35 |
ATROPHY | 2 1 1 2 2 2 1 1 1 2 1 2 2 1 1 1 | 32 1.8|
OVARY | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
ANGIECTASIS | | 2 3.5|
ATROPHY | X X X X X X X X X X X X X X X | 29 |
CONGESTION | | 1 1.0|
CYST | X X X X X X X | 11 |
CYST,PERIOVARIAN TISSUE | X X X X X | 7 |
HEMATOCYST | X X X X X | 7 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
MINERALIZATION | | 1 1.0|
OVOTESTIS | 1 | 1 1.0|
UTERUS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ADENOMYOSIS | 1 | 1 1.0|
ATROPHY | | 3 3.6|
DILATATION | 4 | 3 2.3|
HYPERPLASIA,ATYPICAL | 3 | 1 3.0|
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 1 1 2 2 1 2 3 3 4 1 1 2 2 2 4 2 3 3 3 1 | 38 2.2|
HYPERTROPHY,MYOMETRIUM | 2 | 1 2.0|
VAGINA | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
ATROPHY | | 2 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HYPERPLASIA | 2 1 | 2 1.5|
MYELOFIBROSIS | | 1 4.0|
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HYPERPLASIA,LYMPHOID | | 1 3.0|
HYPERPLASIA,LYMPHOID,RENAL | 3 | 1 3.0|
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HEMORRHAGE | | 1 1.0|
HYPERPLASIA,LYMPHOID | 1 2 1 2 1 | 10 1.5|
INFILTRATION CELLULAR,HISTIOCYTIC | 1 | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 175
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:05.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| S R R|
| 4| 4| 6| 6| 6| 0| 1| 1| 1| 4| 4| 5| 6| 6| 6| 9| 9| 9| 9| 5| 5| 6| 6| U V I|
50MG FS-2YR 22 22 | 3| 4| 6| 7| 8| 9| 0| 1| 2| 1| 2| 9| 0| 1| 2| 5| 6| 7| 8| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
HYPERPLASIA,LYMPHOID | 2 | 3 1.3|
INFILTRATION CELLULAR,HISTIOCYTIC | 2 | 1 2.0|
SPLEEN | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HEMATOCYST | X | 1 |
HEMATOPOIETIC CELL PROLIFERATION | 2 3 2 | 7 2.8|
HYPERPLASIA,LYMPHOID | 1 1 1 1 2 | 18 1.7|
NECROSIS | | 1 1.0|
THYMUS | + + + M + + + + + + + + + + + M + + + + + + + | 40 |
ATROPHY,CORTEX | 3 4 4 2 2 4 2 4 2 4 4 2 2 2 3 2 2 2 4 | 35 2.9|
HYPERPLASIA,LYMPHOID,MEDULLA | 2 2 3 2 2 | 14 2.1|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + + + + + + + + + + + M + M + + + + + + | 46 |
HYPERPLASIA | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
LACTATION | 1 1 1 1 | 12 1.1|
SKIN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
FIBROUS OSTEODYSTROPHY,TURBINATE | 1 2 1 1 1 2 | 10 1.2|
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
FIBROUS OSTEODYSTROPHY | 1 2 | 5 1.2|
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 1 1 1 2 1 1 1 1 2 2 1 2 1 1 2 2 1 2 1 2 | 38 1.3|
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HYDROCEPHALUS | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 176
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:05.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| S R R|
| 4| 4| 6| 6| 6| 0| 1| 1| 1| 4| 4| 5| 6| 6| 6| 9| 9| 9| 9| 5| 5| 6| 6| U V I|
50MG FS-2YR 22 22 | 3| 4| 6| 7| 8| 9| 0| 1| 2| 1| 2| 9| 0| 1| 2| 5| 6| 7| 8| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 2 1 1 1 1 1 1 1 1 1 1 2 | 26 1.1|
PERIPHERAL NERVE | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
CRYSTALS | | 1 1.0|
HYPERPLASIA,ALVEOLAR EPITHELIUM | 2 | 2 1.5|
INFILTRATION CELLULAR,HISTIOCYTIC | 2 1 1 | 6 1.3|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 1 2 1 1 1 1 1 1 1 1 1 1 1 3 1 | 41 1.2|
INFLAMMATION | 2 | 1 2.0|
THROMBUS | 1 | 1 1.0|
NOSE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
TRACHEA | + + + + + M M + + + + + + + + + + + + + + + + | 45 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + + + + + + + + + + + + + + + + | 45 |
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HYPERPLASIA | 1 2 | 2 1.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 | 19 1.0|
LACRIMAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
FOCAL CELLULAR CHANGE | | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 1 1 1 1 1 1 1 1 1 2 1 1 | 34 1.1|
ZYMBAL'S GLAND | + + + + + + + + + + + + + + + + + + + + M + + | 46 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AMYLOID DEPOSITION,GLOMERULUS | 3 | 2 3.5|
CYST,RENAL TUBULE | | 4 1.2|
EDEMA | 3 | 1 3.0|
GLOMERULOSCLEROSIS | | 3 1.3|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 177
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:05.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| S R R|
| 4| 4| 6| 6| 6| 0| 1| 1| 1| 4| 4| 5| 6| 6| 6| 9| 9| 9| 9| 5| 5| 6| 6| U V I|
50MG FS-2YR 22 22 | 3| 4| 6| 7| 8| 9| 0| 1| 2| 1| 2| 9| 0| 1| 2| 5| 6| 7| 8| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM
INFARCT | | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 2 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 | 41 1.1|
PIGMENTATION,RENAL TUBULE | | 1 1.0|
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 3 1 1 1 1 1 1 1 1 1 1 2 1 1 | 39 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 178
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:19.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0|
| 6| 0| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 3| 3| 8|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 7| 1| 2| 2| 3| 3| 5| 5| 6| 6| 8| 8| 9| 9| 1| 1| 1| 2| 3| 5| 5| 5| 5| 6| 2| U V I|
CONTRL MS-2YR 27 27 | 0| 0| 8| 9| 0| 1| 8| 9| 0| 1| 8| 9| 0| 1| 7| 8| 9| 0| 3| 6| 7| 8| 9| 0| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
GALLBLADDER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CALCULUS MICRO OBSERVATION ONLY | X | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
INFLAMMATION | | |
INTESTINE LARGE | + + + + + + + + + + + + + + + + + + + + + + + + A | |
INTESTINE LARGE,CECUM | + + + + + + + + + + + + + + + + + + + + + + + + A | |
HYPERPLASIA,LYMPHOID | | |
HYPERPLASIA,LYMPHOID TISSUE | | |
INTESTINE LARGE,COLON | + + + + + + + + + + + + + + + + + + + + + + + + A | |
HYPERPLASIA,LYMPHOID | | |
INTESTINE LARGE,RECTUM | + + + + + + + + + + + + + M + + + + + + + + + + A | |
INTESTINE SMALL | + + + + + + + + + + + + + + + + + + + + + + + + A | |
INTESTINE SMALL,DUODENUM | + + + + + + + + + + + + + + + + + + + + + + + + A | |
INTESTINE SMALL,ILEUM | + + + + + + + + + + + + + + + + + + + + + + + + A | |
HYPERPLASIA,LYMPHOID | 4 | |
INTESTINE SMALL,JEJUNUM | + + + + + + + + + + + + + + + + + + + + + + + + A | |
HYPERPLASIA,LYMPHOID | | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | 4 | |
BASOPHILIC FOCUS | X X X X X | |
CONGESTION | 3 | |
CYST,BILE DUCT | | |
EOSINOPHILIC FOCUS | X | |
HEMATOPOIETIC CELL PROLIFERATION | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 2 | |
NECROSIS | 1 4 1 | |
REGENERATION | | |
TENSION LIPOIDOSIS | X X X X X X X X | |
THROMBUS | 3 | |
VACUOLIZATION CYTOPLASMIC | 1 | |
MESENTERY | + | |
INFARCT | X | |
PANCREAS | + + + + + + + + + + + + + + + + + + + + + + + + A | |
ATROPHY | 1 1 | |
FOCAL CELLULAR CHANGE | 2 1 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 179
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:19.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0|
| 6| 0| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 3| 3| 8|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 7| 1| 2| 2| 3| 3| 5| 5| 6| 6| 8| 8| 9| 9| 1| 1| 1| 2| 3| 5| 5| 5| 5| 6| 2| U V I|
CONTRL MS-2YR 27 27 | 0| 0| 8| 9| 0| 1| 8| 9| 0| 1| 8| 9| 0| 1| 7| 8| 9| 0| 3| 6| 7| 8| 9| 0| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
HYPERPLASIA | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | |
INFLAMMATION | | |
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + + A | |
FOCAL CELLULAR CHANGE | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 2 1 3 2 2 1 3 3 3 3 2 2 2 1 1 3 2 2 3 1 2 3 2 | |
STOMACH | + + + + + + + + + + + + + + + + + + + + + + + + + | |
STOMACH,FORESTOMACH | + + + + + + + + + + + + + + + + + + + + + + + + + | |
STOMACH,GLANDULAR | + + + + + + + + + + + + + + + + + + + + + + + + A | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + + + + + + + + + + + + + + + + + M | |
BLOOD VESSEL,AORTA | + + + + + + + + + + + + + + + + + + + + + + + + M | |
HEART | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 2| |
DEGENERATION | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | | |
CLEAR CELL FOCUS | X X | |
CONGESTION | 1 | |
FOCAL CELLULAR CHANGE | | |
HYPERPLASIA | 1 1 2 1 | |
HYPERPLASIA,SPINDLE CELL | 2 1 1 1 1 1 1 2 2 2 2 2 1 1 2 1 2 2 1 2 2 | |
ADRENAL GLAND,MEDULLA | + + + + + + + + + + + + + + + M + + + + + + + + + | |
HYPERPLASIA | 1 1 1 | |
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + + A | |
PARATHYROID GLAND | + + + M + + + + + + + M + + + + + + + + + + M + M | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 180
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:19.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0|
| 6| 0| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 3| 3| 8|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 7| 1| 2| 2| 3| 3| 5| 5| 6| 6| 8| 8| 9| 9| 1| 1| 1| 2| 3| 5| 5| 5| 5| 6| 2| U V I|
CONTRL MS-2YR 27 27 | 0| 0| 8| 9| 0| 1| 8| 9| 0| 1| 8| 9| 0| 1| 7| 8| 9| 0| 3| 6| 7| 8| 9| 0| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
PITUITARY GLAND | M + + + + + + + + + + + + + + + + + + + I M + + M | |
CYST | 2 | |
HYPERPLASIA,PARS DISTALIS | 1 | |
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ULTIMOBRANCHIAL CYST | | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
EPIDIDYMIS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
GRANULOMA SPERM | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
MINERALIZATION | | |
PREPUTIAL GLAND | + + + + + + + + + + + + + + + + + M + + + + + + + | |
ATROPHY | 3 | |
CYST | 1 2 | |
ECTASIA | 3 3 1 1 1 1 2 1 2 2 3 1 1 3 2 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 | |
INFLAMMATION | | |
PROSTATE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 2 1 1 2 2 | |
SEMINAL VESICLE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
TESTES | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 2 | |
HYPERPLASIA | | |
PIGMENTATION | | |
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 | |
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + + + + + + + + + + + + + A | |
CONGESTION | 2 3 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 181
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:19.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0|
| 6| 0| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 3| 3| 8|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 7| 1| 2| 2| 3| 3| 5| 5| 6| 6| 8| 8| 9| 9| 1| 1| 1| 2| 3| 5| 5| 5| 5| 6| 2| U V I|
CONTRL MS-2YR 27 27 | 0| 0| 8| 9| 0| 1| 8| 9| 0| 1| 8| 9| 0| 1| 7| 8| 9| 0| 3| 6| 7| 8| 9| 0| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
HEMATOPOIETIC CELL PROLIFERATION | 2 | |
HEMORRHAGE | 1 1 1 1 1 3 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
SPLEEN | + + + + + + + + + + + + + + + + + + + + + + + + A | |
ATROPHY | 3 | |
CONGESTION | 2 | |
CYST | 2 | |
HEMATOPOIETIC CELL PROLIFERATION | 3 3 3 3 | |
HYPERPLASIA,LYMPHOID | 2 | |
THYMUS | M M + + + + + + + + + M + + + M + + + + + M M + A | |
CYST | | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M + M M M M M M M M M M + M M M M M M M M M M M M | |
SKIN | + + + + + + + + + + + + + + + + + + + + + + + + A | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 1 | |
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + + A | |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + + A | |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + + A | |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 2 1 2 1 2 1 1 1 1 1 | |
PERIPHERAL NERVE | + + + + + + M + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + + A | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 182
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:20.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0|
| 6| 0| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 3| 3| 8|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 7| 1| 2| 2| 3| 3| 5| 5| 6| 6| 8| 8| 9| 9| 1| 1| 1| 2| 3| 5| 5| 5| 5| 6| 2| U V I|
CONTRL MS-2YR 27 27 | 0| 0| 8| 9| 0| 1| 8| 9| 0| 1| 8| 9| 0| 1| 7| 8| 9| 0| 3| 6| 7| 8| 9| 0| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + + A | |
CYST,MENINGES | | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | M + + + + + + + + + + + + + + + + + + + + + + + M | |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CONGESTION | 3 3 3 | |
CYST | 1 | |
HEMORRHAGE | | |
HYPERPLASIA,ALVEOLAR EPITHELIUM | 1 1 1 2 1 3 1 | |
INFILTRATION CELLULAR,HISTIOCYTIC | 3 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 2 2 2 2 2 1 3 2 3 1 2 2 2 3 2 2 2 | |
INFLAMMATION | 1 1 | |
MINERALIZATION | | |
NOSE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
TRACHEA | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DEGENERATION | 3 | |
HYPERPLASIA | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 1 1 1 1 2 1 1 1 1 2 1 1 | |
LACRIMAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 1 1 1 1 | |
FOCAL CELLULAR CHANGE | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 2 1 2 1 1 2 1 2 2 | |
ZYMBAL'S GLAND | + + + + + + + + + + + + + + + + + + M M M + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CYST,RENAL TUBULE | | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 183
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:20.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0|
| 6| 0| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 3| 3| 8|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 7| 1| 2| 2| 3| 3| 5| 5| 6| 6| 8| 8| 9| 9| 1| 1| 1| 2| 3| 5| 5| 5| 5| 6| 2| U V I|
CONTRL MS-2YR 27 27 | 0| 0| 8| 9| 0| 1| 8| 9| 0| 1| 8| 9| 0| 1| 7| 8| 9| 0| 3| 6| 7| 8| 9| 0| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 2 1 1 1 2 1 2 2 2 1 2 1 1 1 1 2 1 1 2 | |
MINERALIZATION | 3 1 | |
NEPHROPATHY | 1 | |
VACUOLIZATION CYTOPLASMIC | | |
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 1 2 1 2 1 1 1 1 1 2 2 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 184
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:31.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 2| 3| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 6| S R R|
| 5| 5| 5| 5| 7| 7| 7| 7| 2| 2| 2| 2| 4| 5| 5| 5| 1| 1| 1| 1| 1| 1| 1| U V I|
CONTRL MS-2YR 27 27 | 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
GALLBLADDER | + + + + + + + + + + + + + + + M + + + + + + + | 47 |
CALCULUS MICRO OBSERVATION ONLY | | 1 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 | 6 1.0|
INFLAMMATION | 1 | 1 1.0|
INTESTINE LARGE | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
INTESTINE LARGE,CECUM | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HYPERPLASIA,LYMPHOID | 1 2 | 2 1.5|
HYPERPLASIA,LYMPHOID TISSUE | 2 | 1 2.0|
INTESTINE LARGE,COLON | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HYPERPLASIA,LYMPHOID | 2 | 1 2.0|
INTESTINE LARGE,RECTUM | + + + + + + + + + + + + M + + + + + + + + + + | 45 |
INTESTINE SMALL | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
INTESTINE SMALL,DUODENUM | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
INTESTINE SMALL,ILEUM | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HYPERPLASIA,LYMPHOID | 1 2 | 3 2.3|
INTESTINE SMALL,JEJUNUM | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HYPERPLASIA,LYMPHOID | 1 | 1 1.0|
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ANGIECTASIS | | 1 4.0|
BASOPHILIC FOCUS | X X X X X | 10 |
CONGESTION | | 1 3.0|
CYST,BILE DUCT | 3 | 1 3.0|
EOSINOPHILIC FOCUS | X | 2 |
HEMATOPOIETIC CELL PROLIFERATION | 1 | 2 1.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 1 2 | 11 1.3|
NECROSIS | | 3 2.0|
REGENERATION | 4 | 1 4.0|
TENSION LIPOIDOSIS | X X X X X X X X | 16 |
THROMBUS | | 1 3.0|
VACUOLIZATION CYTOPLASMIC | 2 | 2 1.5|
MESENTERY | | 1 |
INFARCT | | 1 |
PANCREAS | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ATROPHY | | 2 1.0|
FOCAL CELLULAR CHANGE | | 2 1.5|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 185
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:31.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 2| 3| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 6| S R R|
| 5| 5| 5| 5| 7| 7| 7| 7| 2| 2| 2| 2| 4| 5| 5| 5| 1| 1| 1| 1| 1| 1| 1| U V I|
CONTRL MS-2YR 27 27 | 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
HYPERPLASIA | 2 | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 | 6 1.0|
INFLAMMATION | 3 | 1 3.0|
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
FOCAL CELLULAR CHANGE | 1 | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 2 1 2 3 2 2 2 3 2 3 3 1 3 1 2 1 | 43 2.0|
STOMACH | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
STOMACH,FORESTOMACH | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
STOMACH,GLANDULAR | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 2 1.0|
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
BLOOD VESSEL,AORTA | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HEART | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY | | 1 2.0|
DEGENERATION | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 2 1.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY | 2 | 1 2.0|
CLEAR CELL FOCUS | X | 3 |
CONGESTION | | 1 1.0|
FOCAL CELLULAR CHANGE | 1 | 1 1.0|
HYPERPLASIA | 1 1 2 2 2 1 1 | 11 1.3|
HYPERPLASIA,SPINDLE CELL | 1 2 2 1 2 2 1 2 1 2 2 2 2 1 1 1 1 2 2 1 2 1 | 43 1.5|
ADRENAL GLAND,MEDULLA | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HYPERPLASIA | 1 2 3 2 | 7 1.5|
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
PARATHYROID GLAND | M + + + + + + + + + + + + + + + + + + + + + + | 43 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 186
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:32.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 2| 3| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 6| S R R|
| 5| 5| 5| 5| 7| 7| 7| 7| 2| 2| 2| 2| 4| 5| 5| 5| 1| 1| 1| 1| 1| 1| 1| U V I|
CONTRL MS-2YR 27 27 | 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
PITUITARY GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 44 |
CYST | | 1 2.0|
HYPERPLASIA,PARS DISTALIS | 1 1 | 3 1.0|
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ULTIMOBRANCHIAL CYST | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 1 | 3 2.0|
EPIDIDYMIS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
GRANULOMA SPERM | X | 1 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 2 1.0|
MINERALIZATION | 1 | 1 1.0|
PREPUTIAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ATROPHY | 2 | 2 2.5|
CYST | 1 1 | 4 1.2|
ECTASIA | 1 2 1 2 2 2 3 2 1 1 2 3 1 3 | 30 1.8|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 3.0|
INFLAMMATION | 3 | 1 3.0|
PROSTATE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 1 1 1 | 16 1.2|
SEMINAL VESICLE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
TESTES | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY | | 1 2.0|
HYPERPLASIA | 1 1 2 1 | 4 1.2|
PIGMENTATION | 1 | 1 1.0|
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 3 3 | 4 2.7|
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
CONGESTION | 3 3 | 4 2.7|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 187
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:32.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 2| 3| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 6| S R R|
| 5| 5| 5| 5| 7| 7| 7| 7| 2| 2| 2| 2| 4| 5| 5| 5| 1| 1| 1| 1| 1| 1| 1| U V I|
CONTRL MS-2YR 27 27 | 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
HEMATOPOIETIC CELL PROLIFERATION | 2 2 | 3 2.0|
HEMORRHAGE | 1 1 1 | 10 1.3|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 2 | 2 2.0|
SPLEEN | + + + + + + + + + + + + + + + + + + M + + + + | 46 |
ATROPHY | | 1 3.0|
CONGESTION | 3 | 2 2.5|
CYST | | 1 2.0|
HEMATOPOIETIC CELL PROLIFERATION | 3 3 2 3 | 8 2.8|
HYPERPLASIA,LYMPHOID | 1 3 2 3 | 5 2.2|
THYMUS | + + + + + + + + + + + M + M M + + M + M + + + | 36 |
CYST | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M M M M M M M M M M + M M M M M M M M M M M M | 3 |
SKIN | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 1 2.0|
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | | 1 1.0|
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 2 1.0|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
BRAIN,CEREBELLUM | + + M + + + + + + + + + + + + + + + + + + + + | 46 |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
MINERALIZATION,MULTIFOCAL,THALAMUS | 2 2 2 1 2 1 1 2 2 1 2 1 2 | 25 1.4|
PERIPHERAL NERVE | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 188
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:32.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 2| 3| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 6| S R R|
| 5| 5| 5| 5| 7| 7| 7| 7| 2| 2| 2| 2| 4| 5| 5| 5| 1| 1| 1| 1| 1| 1| 1| U V I|
CONTRL MS-2YR 27 27 | 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
CYST,MENINGES | 1 | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + + + + + + + + + + M + + + + + + + + + | 45 |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
CONGESTION | | 3 3.0|
CYST | | 1 1.0|
HEMORRHAGE | 2 | 1 2.0|
HYPERPLASIA,ALVEOLAR EPITHELIUM | 2 1 2 1 | 11 1.4|
INFILTRATION CELLULAR,HISTIOCYTIC | | 1 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 1 1 2 2 2 3 2 3 2 3 3 1 2 3 2 1 3 2 3 2 | 42 2.0|
INFLAMMATION | 1 2 | 4 1.2|
MINERALIZATION | 1 | 1 1.0|
NOSE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
TRACHEA | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
DEGENERATION | | 1 3.0|
HYPERPLASIA | 2 | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 | 25 1.1|
LACRIMAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY | 2 1 | 6 1.1|
FOCAL CELLULAR CHANGE | | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 1 1 | 18 1.3|
ZYMBAL'S GLAND | + + + + + + + + + + + + + + + + M + + + + + + | 44 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 3 1.0|
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
CYST,RENAL TUBULE | 1 | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 189
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:32.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 2| 3| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 6| S R R|
| 5| 5| 5| 5| 7| 7| 7| 7| 2| 2| 2| 2| 4| 5| 5| 5| 1| 1| 1| 1| 1| 1| 1| U V I|
CONTRL MS-2YR 27 27 | 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 2 1 1 2 2 1 2 1 3 2 1 3 1 1 2 1 3 1 3 2 | 45 1.5|
MINERALIZATION | | 2 2.0|
NEPHROPATHY | 3 1 2 2 1 | 6 1.6|
VACUOLIZATION CYTOPLASMIC | 1 | 1 1.0|
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 2 1 2 1 2 1 1 2 | 28 1.3|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 190
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:35.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 2| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1| 7| 7| 7| 7|
| 5| 8| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 7| 2| 4| 4| 4|
| 2| 6| 4| 3| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 3| 3| 3| 8| 8| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| S R R|
| 3| 6| 7| 8| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 9| 2| 3| 3| 4| 6| 3| 4| 4| 4| U V I|
10MG MS-2YR 28 28 | 7| 7| 5| 0| 6| 7| 8| 9| 6| 7| 8| 9| 5| 6| 7| 8| 3| 8| 9| 0| 5| 0| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + | |
GALLBLADDER | A + + + + + | |
INTESTINE LARGE | + A A + + + | |
INTESTINE LARGE,CECUM | + A A + + + | |
HYPERPLASIA,LYMPHOID | | |
INTESTINE LARGE,COLON | + A A + + + | |
INTESTINE LARGE,RECTUM | + A A + + + | |
INTESTINE SMALL | + A A + + + | |
INTESTINE SMALL,DUODENUM | + A A + + + | |
INTESTINE SMALL,ILEUM | + A A + + + | |
INTESTINE SMALL,JEJUNUM | + A A + + + | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | 3 | |
BASOPHILIC FOCUS | X | |
CONGESTION | 3 | |
CYST,BILE DUCT | 3 | |
EOSINOPHILIC FOCUS | X X | |
HEMATOPOIETIC CELL PROLIFERATION | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 1 1 2 | |
REGENERATION | 2 | |
TENSION LIPOIDOSIS | X X X X X X X | |
THROMBUS | 2 | |
VACUOLIZATION CYTOPLASMIC | 2 | |
PANCREAS | + + M + + + | |
SALIVARY GLANDS | + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 3 | |
MINERALIZATION | 1 | |
STOMACH | + + A + + + | |
STOMACH,FORESTOMACH | + + A + + + | |
STOMACH,GLANDULAR | + + A + + + | |
TONGUE | + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + | |
BLOOD VESSEL,AORTA | + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 191
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:35.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 2| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1| 7| 7| 7| 7|
| 5| 8| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 7| 2| 4| 4| 4|
| 2| 6| 4| 3| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 3| 3| 3| 8| 8| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| S R R|
| 3| 6| 7| 8| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 9| 2| 3| 3| 4| 6| 3| 4| 4| 4| U V I|
10MG MS-2YR 28 28 | 7| 7| 5| 0| 6| 7| 8| 9| 6| 7| 8| 9| 5| 6| 7| 8| 3| 8| 9| 0| 5| 0| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM
HEART | + + + + + + | |
FIBROSIS | 1 | |
NECROSIS | 1 | |
PIGMENTATION,VALVE | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | M + + + + + | |
ADRENAL GLAND,CORTEX | M + + + + + | |
HYPERPLASIA,SPINDLE CELL | 1 2 2 1 | |
VACUOLIZATION CYTOPLASMIC | 2 | |
ADRENAL GLAND,MEDULLA | M + + + + + | |
ISLETS, PANCREATIC | + + M + + + | |
PARATHYROID GLAND | + + M + + + | |
PITUITARY GLAND | M + M + + + | |
THYROID GLAND | + + A + + + | |
HYPERTROPHY,FOLLICLE | 1 | |
ULTIMOBRANCHIAL CYST | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + + + + + + | |
EPIDIDYMIS | + + + M + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
INFLAMMATION | 2 | |
PENIS | + | |
CYST | 1| |
PREPUTIAL GLAND | + + + M + + + + + | |
CYST | 1 2 2 2 | |
CYST,MULTIPLE | 2 | |
ECTASIA | 2 2 1 | |
PROSTATE | + + + M + + | |
SEMINAL VESICLE | + + + + + + | |
ECTASIA | | |
TESTES | + + + + + + | |
DEGENERATION | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 192
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:36.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 2| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1| 7| 7| 7| 7|
| 5| 8| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 7| 2| 4| 4| 4|
| 2| 6| 4| 3| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 3| 3| 3| 8| 8| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| S R R|
| 3| 6| 7| 8| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 9| 2| 3| 3| 4| 6| 3| 4| 4| 4| U V I|
10MG MS-2YR 28 28 | 7| 7| 5| 0| 6| 7| 8| 9| 6| 7| 8| 9| 5| 6| 7| 8| 3| 8| 9| 0| 5| 0| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + | |
PIGMENTATION | 1 1 | |
LYMPH NODE | + + + + + + + + + | |
LYMPH NODE,MANDIBULAR | + + + + + + | |
LYMPH NODE,MESENTERIC | A M A + + + + + | |
ANGIECTASIS | 2 | |
HEMORRHAGE | 2 2 2 2 | |
SPLEEN | + + M + + + + + | |
HEMATOPOIETIC CELL PROLIFERATION | 3 3 3 | |
THYMUS | M + + M + + | |
NECROSIS | 2 | |
PIGMENTATION | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M M M M M M | |
SKIN | + + + + + + | |
ATROPHY,SUBCUTANEOUS TISSUE | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + | |
BONE,FEMUR | + + + + + + | |
BONE,STERNUM | + + + + + + | |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | 2 | |
SKELETAL MUSCLE | + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + | |
BRAIN,CEREBRUM | + + + + + + | |
HEMORRHAGE | | |
MINERALIZATION,MULTIFOCAL,THALAMUS | 2 2 | |
PERIPHERAL NERVE | + + + + + + | |
SPINAL CORD | + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 193
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:36.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 2| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1| 7| 7| 7| 7|
| 5| 8| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 7| 2| 4| 4| 4|
| 2| 6| 4| 3| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 3| 3| 3| 8| 8| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| S R R|
| 3| 6| 7| 8| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 9| 2| 3| 3| 4| 6| 3| 4| 4| 4| U V I|
10MG MS-2YR 28 28 | 7| 7| 5| 0| 6| 7| 8| 9| 6| 7| 8| 9| 5| 6| 7| 8| 3| 8| 9| 0| 5| 0| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
SPINAL CORD,THORACIC | + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + M + + + | |
LUNG | + + + + + + + | |
HEMORRHAGE | | |
INFILTRATION CELLULAR,HISTIOCYTIC | 3 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 | |
INFLAMMATION | 3 | |
NOSE | + + + + + + | |
TRACHEA | + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | A + + + + + + | |
INFLAMMATION,CORNEA | 1 | |
HARDERIAN GLAND | + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 | |
LACRIMAL GLAND | + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
ZYMBAL'S GLAND | + + + M M + | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + | |
CONGESTION | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 | |
INFLAMMATION | 1 | |
URINARY BLADDER | + + + + + + | |
ECTASIA | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
INFLAMMATION | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 194
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:36.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 3| 3| 3| 3| 0| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| S R R|
| 6| 7| 7| 7| 8| 1| 1| 1| 4| 4| 4| 9| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| U V I|
10MG MS-2YR 28 28 | 9| 0| 1| 2| 8| 3| 4| 5| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 2| 3| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + | 7 |
GALLBLADDER | + | 6 |
INTESTINE LARGE | + | 5 |
INTESTINE LARGE,CECUM | + | 5 |
HYPERPLASIA,LYMPHOID | 2 | 1 2.0|
INTESTINE LARGE,COLON | + | 5 |
INTESTINE LARGE,RECTUM | + | 5 |
INTESTINE SMALL | + + | 6 |
INTESTINE SMALL,DUODENUM | + | 5 |
INTESTINE SMALL,ILEUM | + | 5 |
INTESTINE SMALL,JEJUNUM | + + | 6 |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ANGIECTASIS | | 1 3.0|
BASOPHILIC FOCUS | X | 2 |
CONGESTION | | 1 3.0|
CYST,BILE DUCT | 1 2 1 | 4 1.7|
EOSINOPHILIC FOCUS | | 2 |
HEMATOPOIETIC CELL PROLIFERATION | 1 1 | 2 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 1 1 1 | 17 1.1|
REGENERATION | | 1 2.0|
TENSION LIPOIDOSIS | X X X X X X | 13 |
THROMBUS | | 1 2.0|
VACUOLIZATION CYTOPLASMIC | | 1 2.0|
PANCREAS | + | 6 |
SALIVARY GLANDS | + | 7 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 3 1.6|
MINERALIZATION | | 1 1.0|
STOMACH | + | 6 |
STOMACH,FORESTOMACH | + | 6 |
STOMACH,GLANDULAR | + | 6 |
TONGUE | + | 7 |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + | 7 |
BLOOD VESSEL,AORTA | + | 7 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 195
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:37.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 3| 3| 3| 3| 0| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| S R R|
| 6| 7| 7| 7| 8| 1| 1| 1| 4| 4| 4| 9| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| U V I|
10MG MS-2YR 28 28 | 9| 0| 1| 2| 8| 3| 4| 5| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 2| 3| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM
HEART | + | 7 |
FIBROSIS | | 1 1.0|
NECROSIS | | 1 1.0|
PIGMENTATION,VALVE | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + | 6 |
ADRENAL GLAND,CORTEX | + | 6 |
HYPERPLASIA,SPINDLE CELL | 1 | 5 1.4|
VACUOLIZATION CYTOPLASMIC | | 1 2.0|
ADRENAL GLAND,MEDULLA | + | 6 |
ISLETS, PANCREATIC | + | 6 |
PARATHYROID GLAND | + | 6 |
PITUITARY GLAND | + | 5 |
THYROID GLAND | + | 6 |
HYPERTROPHY,FOLLICLE | | 1 1.0|
ULTIMOBRANCHIAL CYST | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + | 7 |
EPIDIDYMIS | + | 6 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
INFLAMMATION | | 1 2.0|
PENIS | | 1 |
CYST | | 1 1.0|
PREPUTIAL GLAND | + + | 10 |
CYST | 1 | 5 1.6|
CYST,MULTIPLE | | 1 2.0|
ECTASIA | 1 | 4 1.5|
PROSTATE | + | 6 |
SEMINAL VESICLE | + + | 8 |
ECTASIA | 1 | 1 1.0|
TESTES | + | 7 |
DEGENERATION | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 196
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:37.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 3| 3| 3| 3| 0| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| S R R|
| 6| 7| 7| 7| 8| 1| 1| 1| 4| 4| 4| 9| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| U V I|
10MG MS-2YR 28 28 | 9| 0| 1| 2| 8| 3| 4| 5| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 2| 3| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
BONE MARROW | + | 7 |
PIGMENTATION | | 2 1.0|
LYMPH NODE | + + | 11 |
LYMPH NODE,MANDIBULAR | + | 7 |
LYMPH NODE,MESENTERIC | + + | 7 |
ANGIECTASIS | | 1 2.0|
HEMORRHAGE | | 4 2.0|
SPLEEN | + + + + | 11 |
HEMATOPOIETIC CELL PROLIFERATION | 3 3 | 5 3.0|
THYMUS | + | 5 |
NECROSIS | | 1 2.0|
PIGMENTATION | | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M | 0 |
SKIN | + + + | 9 |
ATROPHY,SUBCUTANEOUS TISSUE | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + | 7 |
BONE,FEMUR | + | 7 |
BONE,STERNUM | + | 7 |
FIBROUS OSTEODYSTROPHY,MULTIFOCAL | | 1 2.0|
SKELETAL MUSCLE | + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + | 7 |
BRAIN,CEREBELLUM | + | 7 |
BRAIN,CEREBRUM | + | 7 |
HEMORRHAGE | 3 | 1 3.0|
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 | 3 1.6|
PERIPHERAL NERVE | + | 7 |
SPINAL CORD | + | 7 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 197
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:37.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 3| 3| 3| 3| 0| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| S R R|
| 6| 7| 7| 7| 8| 1| 1| 1| 4| 4| 4| 9| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| U V I|
10MG MS-2YR 28 28 | 9| 0| 1| 2| 8| 3| 4| 5| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 2| 3| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
SPINAL CORD,THORACIC | + | 7 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + | 6 |
LUNG | + | 8 |
HEMORRHAGE | 1 | 1 1.0|
INFILTRATION CELLULAR,HISTIOCYTIC | | 1 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 3 1.3|
INFLAMMATION | | 1 3.0|
NOSE | + | 7 |
TRACHEA | + | 7 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + | 7 |
INFLAMMATION,CORNEA | | 1 1.0|
HARDERIAN GLAND | + + | 10 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 3 1.0|
LACRIMAL GLAND | + | 7 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
ZYMBAL'S GLAND | M | 4 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + | 8 |
CONGESTION | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 4 1.2|
INFLAMMATION | | 1 1.0|
URINARY BLADDER | + | 7 |
ECTASIA | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
INFLAMMATION | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 198
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:38.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 1| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 1| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 3| 3| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 7| 0| 2| 2| 2| 2| 5| 5| 5| 5| 8| 8| 8| 8| 1| 1| 1| 1| 2| 2| 2| 3| 3| 3| 5| U V I|
25MG MS-2YR 29 29 | 9| 7| 4| 5| 6| 7| 4| 5| 6| 7| 4| 5| 6| 7| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + | |
GALLBLADDER | + M | |
INTESTINE LARGE | + A | |
INTESTINE LARGE,CECUM | + A | |
INTESTINE LARGE,COLON | + A | |
INTESTINE LARGE,RECTUM | + A | |
INTESTINE SMALL | A A | |
INTESTINE SMALL,DUODENUM | A A | |
INTESTINE SMALL,ILEUM | A A | |
INTESTINE SMALL,JEJUNUM | A A | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | 3 | |
BASOPHILIC FOCUS | X X X X X X X | |
CYST,BILE DUCT | | |
EOSINOPHILIC FOCUS | X | |
HYPERPLASIA,ITO CELL | | |
INFARCT | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 2 1 1 | |
NECROSIS | 2 1 | |
TENSION LIPOIDOSIS | X X X X X | |
VACUOLIZATION CYTOPLASMIC | 1 | |
PANCREAS | + + | |
INFLAMMATION | 3 | |
SALIVARY GLANDS | + + | |
STOMACH | + A | |
STOMACH,FORESTOMACH | + A | |
STOMACH,GLANDULAR | + A | |
TONGUE | + + | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + | |
BLOOD VESSEL,AORTA | + + | |
HEART | + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 199
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:38.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 1| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 1| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 3| 3| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 7| 0| 2| 2| 2| 2| 5| 5| 5| 5| 8| 8| 8| 8| 1| 1| 1| 1| 2| 2| 2| 3| 3| 3| 5| U V I|
25MG MS-2YR 29 29 | 9| 7| 4| 5| 6| 7| 4| 5| 6| 7| 4| 5| 6| 7| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
ADRENAL GLAND | + + | |
ADRENAL GLAND,CORTEX | + + | |
ADRENAL GLAND,MEDULLA | + + | |
ISLETS, PANCREATIC | + + | |
PARATHYROID GLAND | + + | |
PITUITARY GLAND | + A | |
THYROID GLAND | + + | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + A | |
EPIDIDYMIS | + + | |
PREPUTIAL GLAND | + M + + | |
CYST | 1 1 | |
ECTASIA | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
INFLAMMATION | | |
NECROSIS,FAT | 2 | |
PROSTATE | + + | |
SEMINAL VESICLE | + A | |
TESTES | + + | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + | |
LYMPH NODE | + + + + | |
LYMPH NODE,MANDIBULAR | + + | |
LYMPH NODE,MESENTERIC | + + + + | |
CONGESTION | 3 | |
HEMORRHAGE | 2 | |
HYPERPLASIA,LYMPHOID | 2 | |
SPLEEN | + + + + | |
HEMATOPOIETIC CELL PROLIFERATION | 3 | |
HYPERPLASIA,LYMPHOID | 1 | |
THYMUS | + M | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 200
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:38.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 1| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 1| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 3| 3| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 7| 0| 2| 2| 2| 2| 5| 5| 5| 5| 8| 8| 8| 8| 1| 1| 1| 1| 2| 2| 2| 3| 3| 3| 5| U V I|
25MG MS-2YR 29 29 | 9| 7| 4| 5| 6| 7| 4| 5| 6| 7| 4| 5| 6| 7| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
ATROPHY,CORTEX | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M M | |
SKIN | + + + | |
ATROPHY,SUBCUTANEOUS TISSUE | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + | |
BONE,FEMUR | + + | |
BONE,STERNUM | + + | |
SKELETAL MUSCLE | + + | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + | |
BRAIN,CEREBELLUM | + + | |
BRAIN,CEREBRUM | + + | |
MINERALIZATION,MULTIFOCAL,THALAMUS | 2 | |
PERIPHERAL NERVE | + + | |
SPINAL CORD | + + | |
SPINAL CORD,THORACIC | + + | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + M | |
LUNG | + + | |
NOSE | + + | |
TRACHEA | + + | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + | |
HARDERIAN GLAND | + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 201
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:39.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 1| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 1| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 3| 3| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 7| 0| 2| 2| 2| 2| 5| 5| 5| 5| 8| 8| 8| 8| 1| 1| 1| 1| 2| 2| 2| 3| 3| 3| 5| U V I|
25MG MS-2YR 29 29 | 9| 7| 4| 5| 6| 7| 4| 5| 6| 7| 4| 5| 6| 7| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | |
LACRIMAL GLAND | + A | |
ZYMBAL'S GLAND | + + | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
NEPHROPATHY | 1 1 | |
URINARY BLADDER | + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 202
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:39.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 3| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 6| 6| S R R|
| 5| 5| 5| 8| 8| 8| 8| 2| 2| 2| 2| 5| 5| 5| 5| 2| 2| 2| 2| 2| 2| 2| 2| U V I|
25MG MS-2YR 29 29 | 6| 7| 8| 0| 1| 2| 3| 4| 5| 6| 7| 3| 4| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | | 2 |
GALLBLADDER | | 1 |
INTESTINE LARGE | | 1 |
INTESTINE LARGE,CECUM | | 1 |
INTESTINE LARGE,COLON | | 1 |
INTESTINE LARGE,RECTUM | | 1 |
INTESTINE SMALL | + | 1 |
INTESTINE SMALL,DUODENUM | + | 1 |
INTESTINE SMALL,ILEUM | | 0 |
INTESTINE SMALL,JEJUNUM | | 0 |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ANGIECTASIS | | 1 3.0|
BASOPHILIC FOCUS | X X | 9 |
CYST,BILE DUCT | 1 2 1 | 3 1.3|
EOSINOPHILIC FOCUS | | 1 |
HYPERPLASIA,ITO CELL | 3 | 1 3.0|
INFARCT | 1 2 | 2 1.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 3 1 2 2 1 1 | 15 1.3|
NECROSIS | 1 | 3 1.3|
TENSION LIPOIDOSIS | X X X X | 9 |
VACUOLIZATION CYTOPLASMIC | 1 | 2 1.0|
PANCREAS | | 2 |
INFLAMMATION | | 1 3.0|
SALIVARY GLANDS | + | 3 |
STOMACH | | 1 |
STOMACH,FORESTOMACH | | 1 |
STOMACH,GLANDULAR | | 1 |
TONGUE | | 2 |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | | 2 |
BLOOD VESSEL,AORTA | | 2 |
HEART | | 2 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 203
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:39.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 3| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 6| 6| S R R|
| 5| 5| 5| 8| 8| 8| 8| 2| 2| 2| 2| 5| 5| 5| 5| 2| 2| 2| 2| 2| 2| 2| 2| U V I|
25MG MS-2YR 29 29 | 6| 7| 8| 0| 1| 2| 3| 4| 5| 6| 7| 3| 4| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
ADRENAL GLAND | | 2 |
ADRENAL GLAND,CORTEX | | 2 |
ADRENAL GLAND,MEDULLA | | 2 |
ISLETS, PANCREATIC | + | 3 |
PARATHYROID GLAND | | 2 |
PITUITARY GLAND | | 1 |
THYROID GLAND | | 2 |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | | 1 |
EPIDIDYMIS | | 2 |
PREPUTIAL GLAND | + + + | 6 |
CYST | 2 2 | 4 1.5|
ECTASIA | 2 | 2 1.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
INFLAMMATION | 2 | 1 2.0|
NECROSIS,FAT | | 1 2.0|
PROSTATE | | 2 |
SEMINAL VESICLE | | 1 |
TESTES | | 2 |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | | 2 |
LYMPH NODE | | 4 |
LYMPH NODE,MANDIBULAR | | 2 |
LYMPH NODE,MESENTERIC | | 4 |
CONGESTION | | 1 3.0|
HEMORRHAGE | | 1 2.0|
HYPERPLASIA,LYMPHOID | | 1 2.0|
SPLEEN | | 4 |
HEMATOPOIETIC CELL PROLIFERATION | | 1 3.0|
HYPERPLASIA,LYMPHOID | | 1 1.0|
THYMUS | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 204
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:39.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 3| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 6| 6| S R R|
| 5| 5| 5| 8| 8| 8| 8| 2| 2| 2| 2| 5| 5| 5| 5| 2| 2| 2| 2| 2| 2| 2| 2| U V I|
25MG MS-2YR 29 29 | 6| 7| 8| 0| 1| 2| 3| 4| 5| 6| 7| 3| 4| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
ATROPHY,CORTEX | | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | | 0 |
SKIN | | 3 |
ATROPHY,SUBCUTANEOUS TISSUE | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | | 2 |
BONE,FEMUR | | 2 |
BONE,STERNUM | | 2 |
SKELETAL MUSCLE | | 2 |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | | 2 |
BRAIN,CEREBELLUM | | 2 |
BRAIN,CEREBRUM | | 2 |
MINERALIZATION,MULTIFOCAL,THALAMUS | | 1 2.0|
PERIPHERAL NERVE | | 2 |
SPINAL CORD | | 2 |
SPINAL CORD,THORACIC | | 2 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | | 1 |
LUNG | + + | 4 |
NOSE | | 2 |
TRACHEA | | 2 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | | 2 |
HARDERIAN GLAND | + + | 4 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 205
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:39.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 2| 2| 2| 3| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 6| 6| S R R|
| 5| 5| 5| 8| 8| 8| 8| 2| 2| 2| 2| 5| 5| 5| 5| 2| 2| 2| 2| 2| 2| 2| 2| U V I|
25MG MS-2YR 29 29 | 6| 7| 8| 0| 1| 2| 3| 4| 5| 6| 7| 3| 4| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
INFILTRATION CELLULAR,LYMPHOCYTIC | | 2 1.0|
LACRIMAL GLAND | | 1 |
ZYMBAL'S GLAND | | 2 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | | 2 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
NEPHROPATHY | | 2 1.0|
URINARY BLADDER | | 2 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 206
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:52.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
| 0| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 2| 7| 9|
| 9| 1| 5| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 4| 4| 3| 3| 3| 3| 3| 3| 1| 8| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| S R R|
| 0| 0| 1| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 2| 2| 3| 3| 3| 3| 6| 6| 9| 1| 2| U V I|
50MG MS-2YR 30 30 | 4| 6| 1| 2| 3| 4| 5| 2| 3| 4| 5| 2| 3| 4| 1| 2| 4| 5| 6| 7| 1| 2| 2| 1| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | M + + + + + + + + + + + + + + + + + + + + + + + + | |
INFLAMMATION | 3 | |
GALLBLADDER | M + + + + + + + + + + + + + + M + + + + + + + + M | |
ECTASIA | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | |
INFLAMMATION | | |
INTESTINE LARGE | A + + + + + + + + + + + + + + + + + + + + + + + + | |
INTESTINE LARGE,CECUM | A + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | 2 3 1 | |
HYPERPLASIA,LYMPHOID TISSUE | 2 | |
INTESTINE LARGE,COLON | A + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | 2 | |
INTESTINE LARGE,RECTUM | A + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | | |
INTESTINE SMALL | A + + + + + + + + + + + + + + + + + + + + + + + + | |
INTESTINE SMALL,DUODENUM | A + + + + + + + + + + + + + + + + + + + + + + + + | |
INTESTINE SMALL,ILEUM | A + A + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | 2 | |
INTESTINE SMALL,JEJUNUM | A + A + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,LYMPHOID | 2 | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | | |
BASOPHILIC FOCUS | X X X X X | |
CYST,BILE DUCT | | |
DEGENERATION | 3 2 | |
EOSINOPHILIC FOCUS | X X | |
HEMATOPOIETIC CELL PROLIFERATION | 1 | |
INFARCT | 4 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
NECROSIS | 2 3 | |
REGENERATION | 3 | |
TENSION LIPOIDOSIS | X X X | |
VACUOLIZATION CYTOPLASMIC | 2 | |
PANCREAS | A + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | | |
BASOPHILIC FOCUS | X | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 207
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:52.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
| 0| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 2| 7| 9|
| 9| 1| 5| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 4| 4| 3| 3| 3| 3| 3| 3| 1| 8| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| S R R|
| 0| 0| 1| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 2| 2| 3| 3| 3| 3| 6| 6| 9| 1| 2| U V I|
50MG MS-2YR 30 30 | 4| 6| 1| 2| 3| 4| 5| 2| 3| 4| 5| 2| 3| 4| 1| 2| 4| 5| 6| 7| 1| 2| 2| 1| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
FOCAL CELLULAR CHANGE | 1 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
INFLAMMATION | 3 | |
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 2 2 1 1 1 3 2 3 2 2 3 3 1 1 2 1 1 2 2 1 1| |
STOMACH | A + + + + + + + + + + + + + + + + + + + + + + + + | |
STOMACH,FORESTOMACH | A + + + + + + + + + + + + + + + + + + + + + + + + | |
STOMACH,GLANDULAR | A + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | |
INFLAMMATION | | |
MINERALIZATION | 1 | |
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | A + + + + + + + + + + + + + + + + + + + + + + + + | |
BLOOD VESSEL,AORTA | A + + + + + + + + + + + + + + + + + + + + + + + + | |
HEART | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | A + + + + + + + + + + + + + + + + + + + + + + + + | |
ADRENAL GLAND,CORTEX | A + + + + + + + + + + + + + + + + + + + + + + + + | |
CLEAR CELL FOCUS | X | |
FOCAL CELLULAR CHANGE | 1 | |
HYPERPLASIA | 1 1 2 2 2 | |
HYPERPLASIA,SPINDLE CELL | 2 2 2 1 1 1 2 2 1 2 1 2 1 2 3 2 3 2 1| |
NECROSIS | 4 | |
ADRENAL GLAND,MEDULLA | A + + + + + + + + + + + + + + + + + + + + + + + + | |
FIBROSIS | | |
HYPERPLASIA | 2 3 1 1 2 3 | |
NECROSIS | 4 | |
ISLETS, PANCREATIC | A + + + + + + + + + + + + + + + + + + + + + + + + | |
PARATHYROID GLAND | M + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 208
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:53.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
| 0| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 2| 7| 9|
| 9| 1| 5| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 4| 4| 3| 3| 3| 3| 3| 3| 1| 8| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| S R R|
| 0| 0| 1| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 2| 2| 3| 3| 3| 3| 6| 6| 9| 1| 2| U V I|
50MG MS-2YR 30 30 | 4| 6| 1| 2| 3| 4| 5| 2| 3| 4| 5| 2| 3| 4| 1| 2| 4| 5| 6| 7| 1| 2| 2| 1| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
CYST | 1 | |
ECTOPIC THYMUS | X | |
PITUITARY GLAND | M M + + + + + M + + + + + + + + M + + + + + M M M | |
HYPERPLASIA,PARS DISTALIS | 1 1 | |
THYROID GLAND | M + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
GENERAL BODY SYSTEM
TISSUE NOS | + | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + + + + + + + + + + + + + + + + + + + + + + + + M | |
ATROPHY | | |
EPIDIDYMIS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
PREPUTIAL GLAND | + + + + + + + + + + + + M + + + + + + + + + + + + | |
ATROPHY | 3 | |
CYST | 3 2 | |
ECTASIA | 3 3 2 1 2 1 1 1 2 2 2 2 1 3 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 | |
INFLAMMATION | 2 2 | |
PROSTATE | M + + + + + + + + + + + + + + + + + + + + + + + + | |
FIBROSIS | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 2 2 1 | |
INFLAMMATION | 2 | |
SEMINAL VESICLE | + + + + + + + + + + + + + + + + + + + + + + + + M | |
ATROPHY | | |
TESTES | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DEGENERATION | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
MINERALIZATION | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 209
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:53.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
| 0| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 2| 7| 9|
| 9| 1| 5| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 4| 4| 3| 3| 3| 3| 3| 3| 1| 8| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| S R R|
| 0| 0| 1| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 2| 2| 3| 3| 3| 3| 6| 6| 9| 1| 2| U V I|
50MG MS-2YR 30 30 | 4| 6| 1| 2| 3| 4| 5| 2| 3| 4| 5| 2| 3| 4| 1| 2| 4| 5| 6| 7| 1| 2| 2| 1| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CONGESTION | 3 | |
HYPERPLASIA | 2 2| |
PIGMENTATION | 1 2| |
LYMPH NODE | A + + + + + + + + + + + + + + + + + + + + + + + + | |
LYMPH NODE,MANDIBULAR | A + + + + + + + + + + + + + + + + + + + + + + + + | |
HEMATOPOIETIC CELL PROLIFERATION | 2| |
HYPERPLASIA,LYMPHOID | 1 | |
LYMPH NODE,MESENTERIC | A + + + + + + + + + + + + + + + + + + + + + + M + | |
CONGESTION | 4 3 | |
HEMATOPOIETIC CELL PROLIFERATION | 1 | |
HEMORRHAGE | 2 1 1 3 2 1| |
HYPERPLASIA,LYMPHOID | 1 | |
INFLAMMATION | 2 | |
SPLEEN | A + + + + + + + + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | 2 | |
ATROPHY | | |
CONGESTION | | |
HEMATOPOIETIC CELL PROLIFERATION | 3 3 3 3 1 4 3 | |
HYPERPLASIA,LYMPHOID | 2 2 3 | |
INFARCT | | |
THYMUS | M M + + + + + + + + + M + + M + + + + + + + + M M | |
ATROPHY,CORTEX | | |
CYST | 1 | |
HYPERPLASIA,LYMPHOID,MEDULLA | 2 | |
INFILTRATION CELLULAR,HISTIOCYTIC | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M + M M M M M + M M M M M M M M M M M M M M M M M | |
SKIN | + + + + + + + M + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 210
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:53.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
| 0| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 2| 7| 9|
| 9| 1| 5| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 4| 4| 3| 3| 3| 3| 3| 3| 1| 8| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| S R R|
| 0| 0| 1| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 2| 2| 3| 3| 3| 3| 6| 6| 9| 1| 2| U V I|
50MG MS-2YR 30 30 | 4| 6| 1| 2| 3| 4| 5| 2| 3| 4| 5| 2| 3| 4| 1| 2| 4| 5| 6| 7| 1| 2| 2| 1| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + + + + + + M + + + + + + + + + + + + | |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
MINERALIZATION,MULTIFOCAL,THALAMUS | 2 2 1 2 1 | |
PERIPHERAL NERVE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + + + | |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + M + + + + + + + + + + + + + + + + + + + + + + | |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CONGESTION | 3| |
HYPERPLASIA,ALVEOLAR EPITHELIUM | 2 3 2 1 | |
INFILTRATION CELLULAR,HISTIOCYTIC | 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 2 3 1 2 1 2 3 3 3 1 2 1 2 1 4 2 2 1| |
NOSE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
INFLAMMATION | | |
TRACHEA | M + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 1 2 1 1 1 1 1 1 1 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 211
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:39:53.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
| 0| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 2| 7| 9|
| 9| 1| 5| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 4| 4| 3| 3| 3| 3| 3| 3| 1| 8| 6|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| S R R|
| 0| 0| 1| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 2| 2| 3| 3| 3| 3| 6| 6| 9| 1| 2| U V I|
50MG MS-2YR 30 30 | 4| 6| 1| 2| 3| 4| 5| 2| 3| 4| 5| 2| 3| 4| 1| 2| 4| 5| 6| 7| 1| 2| 2| 1| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
INFLAMMATION | 3| |
LACRIMAL GLAND | A + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 1 | |
VACUOLIZATION CYTOPLASMIC | 2| |
ZYMBAL'S GLAND | + + + + + M + + + + + + + + + + + + + + + + + + + | |
INFLAMMATION | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | A + + + + + + + + + + + + + + + + + + + + + + + + | |
CONGESTION | 3 | |
FOCAL CELLULAR CHANGE | 1 | |
INFARCT | 4 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 2 1 3 1 2 3 1 1 1 1 2 1 2 2 2 | |
INFILTRATION CELLULAR,PLASMA CELL | 1| |
INFLAMMATION | 3 | |
MINERALIZATION | 1 | |
NEPHROPATHY | 1 1 2| |
PIGMENTATION,RENAL TUBULE | 1 | |
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 2 1 1 1 1 1 1 | |
INFLAMMATION | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 212
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:40:05.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 0| 1| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 7| 7| S R R|
| 2| 2| 4| 4| 5| 7| 7| 7| 1| 1| 1| 1| 4| 4| 4| 0| 0| 0| 1| 1| 1| 2| 2| U V I|
50MG MS-2YR 30 30 | 5| 8| 8| 9| 0| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 7| 8| 9| 0| 1| 2| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
INFLAMMATION | | 1 3.0|
GALLBLADDER | + + + + + M + + + + + + + + + + + M + + + + + | 43 |
ECTASIA | 3 3 | 2 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 2 1.0|
INFLAMMATION | 1 | 1 1.0|
INTESTINE LARGE | + A + + + + + + + + + + + + + + + + + + + + + | 46 |
INTESTINE LARGE,CECUM | + A + + + + + + + + + + + + + + + + + + + + + | 46 |
HYPERPLASIA,LYMPHOID | | 3 2.0|
HYPERPLASIA,LYMPHOID TISSUE | | 1 2.0|
INTESTINE LARGE,COLON | + A + + + + + + + + + + + + + + + + + + + + + | 46 |
HYPERPLASIA,LYMPHOID | | 1 2.0|
INTESTINE LARGE,RECTUM | + M + + + + + + + + + + + + + + + M + + + + + | 45 |
HYPERPLASIA,LYMPHOID | 2 | 1 2.0|
INTESTINE SMALL | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
INTESTINE SMALL,DUODENUM | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
INTESTINE SMALL,ILEUM | + A + + + + + + + + + + + + + + + + + + + + + | 45 |
HYPERPLASIA,LYMPHOID | 2 | 2 2.0|
INTESTINE SMALL,JEJUNUM | + A + + + + + + + + + + + + + + + + + + + + + | 45 |
HYPERPLASIA,LYMPHOID | | 1 2.0|
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ANGIECTASIS | 3 2 | 2 2.5|
BASOPHILIC FOCUS | X X X X X X | 11 |
CYST,BILE DUCT | 2 | 1 2.0|
DEGENERATION | | 2 2.5|
EOSINOPHILIC FOCUS | | 2 |
HEMATOPOIETIC CELL PROLIFERATION | | 1 1.0|
INFARCT | | 1 4.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 2 | 3 1.6|
NECROSIS | 1 2 1 1 | 6 1.6|
REGENERATION | | 1 3.0|
TENSION LIPOIDOSIS | X X X X X X X | 10 |
VACUOLIZATION CYTOPLASMIC | 2 | 2 2.0|
PANCREAS | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ATROPHY | 1 | 1 1.0|
BASOPHILIC FOCUS | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 213
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:40:05.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 0| 1| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 7| 7| S R R|
| 2| 2| 4| 4| 5| 7| 7| 7| 1| 1| 1| 1| 4| 4| 4| 0| 0| 0| 1| 1| 1| 2| 2| U V I|
50MG MS-2YR 30 30 | 5| 8| 8| 9| 0| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 7| 8| 9| 0| 1| 2| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
FOCAL CELLULAR CHANGE | 1 2 | 5 1.2|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 | 6 1.0|
INFLAMMATION | | 1 3.0|
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY | 1 | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 3 3 3 2 1 1 1 2 1 3 1 1 2 1 1 1 2 2 1 | 42 1.7|
STOMACH | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
STOMACH,FORESTOMACH | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
STOMACH,GLANDULAR | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HYPERPLASIA | | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 2 1.0|
INFLAMMATION | 2 3 | 2 2.5|
MINERALIZATION | | 1 1.0|
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | M + + + + + + + + + + + + + + + + + + + + + + | 46 |
BLOOD VESSEL,AORTA | M + + + + + + + + + + + + + + + + + + + + + + | 46 |
HEART | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
CLEAR CELL FOCUS | X X X | 4 |
FOCAL CELLULAR CHANGE | 1 | 2 1.0|
HYPERPLASIA | 1 1 1 2 2 | 10 1.5|
HYPERPLASIA,SPINDLE CELL | 2 1 2 1 2 1 3 3 1 3 2 2 2 2 2 2 1 1 1 2 2 1 1 | 42 1.7|
NECROSIS | | 1 4.0|
ADRENAL GLAND,MEDULLA | + + + + + + + + M + + + + + + + + + + + + + + | 46 |
FIBROSIS | 1 1 | 2 1.0|
HYPERPLASIA | 2 2 2 1 2 1 1 | 13 1.7|
NECROSIS | | 1 4.0|
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
PARATHYROID GLAND | + + + + + + + + + + + + + + + + + M + + + + + | 46 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 214
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:40:05.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 0| 1| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 7| 7| S R R|
| 2| 2| 4| 4| 5| 7| 7| 7| 1| 1| 1| 1| 4| 4| 4| 0| 0| 0| 1| 1| 1| 2| 2| U V I|
50MG MS-2YR 30 30 | 5| 8| 8| 9| 0| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 7| 8| 9| 0| 1| 2| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
CYST | 1 | 2 1.0|
ECTOPIC THYMUS | | 1 |
PITUITARY GLAND | M M + + + + + + + + + + + M + + + M + + + M + | 36 |
HYPERPLASIA,PARS DISTALIS | | 2 1.0|
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
------------------------------------------------------------------------------------------------------------------------------------
GENERAL BODY SYSTEM
TISSUE NOS | M | 1 |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + M + + + + + + + + + + + + + + + + + + + + + | 46 |
ATROPHY | 1 | 1 1.0|
EPIDIDYMIS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 1 2.0|
PREPUTIAL GLAND | + M + + + + + + + + + + + + + + + + + + + + + | 46 |
ATROPHY | | 1 3.0|
CYST | 2 1 2 | 5 2.0|
ECTASIA | 1 2 1 1 1 2 1 1 1 1 | 26 1.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 4 1.2|
INFLAMMATION | | 2 2.0|
PROSTATE | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
FIBROSIS | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 | 10 1.3|
INFLAMMATION | | 1 2.0|
SEMINAL VESICLE | + M + + + + + + + + + + + + + + + + + + + + + | 46 |
ATROPHY | 1 | 1 1.0|
TESTES | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
DEGENERATION | | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
MINERALIZATION | 1 | 2 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 215
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:40:05.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 0| 1| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 7| 7| S R R|
| 2| 2| 4| 4| 5| 7| 7| 7| 1| 1| 1| 1| 4| 4| 4| 0| 0| 0| 1| 1| 1| 2| 2| U V I|
50MG MS-2YR 30 30 | 5| 8| 8| 9| 0| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 7| 8| 9| 0| 1| 2| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
CONGESTION | | 1 3.0|
HYPERPLASIA | 2 2 | 4 2.0|
PIGMENTATION | 2 | 3 1.6|
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + + + + + + + + M | 46 |
HEMATOPOIETIC CELL PROLIFERATION | | 1 2.0|
HYPERPLASIA,LYMPHOID | 2 | 2 1.5|
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
CONGESTION | | 2 3.5|
HEMATOPOIETIC CELL PROLIFERATION | | 1 1.0|
HEMORRHAGE | 2 1 2 1 1 1 2 1 2 1 1 2 1 1 | 20 1.4|
HYPERPLASIA,LYMPHOID | | 1 1.0|
INFLAMMATION | 2 | 2 2.0|
SPLEEN | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ANGIECTASIS | | 1 2.0|
ATROPHY | 2 2 | 2 2.0|
CONGESTION | 1 | 1 1.0|
HEMATOPOIETIC CELL PROLIFERATION | 3 3 3 | 10 2.9|
HYPERPLASIA,LYMPHOID | 2 2 2 | 6 2.1|
INFARCT | 2 1 | 2 1.5|
THYMUS | M M + + M M + + + + + M + + + + + M + M + + + | 35 |
ATROPHY,CORTEX | 3 | 1 3.0|
CYST | | 1 1.0|
HYPERPLASIA,LYMPHOID,MEDULLA | | 1 2.0|
INFILTRATION CELLULAR,HISTIOCYTIC | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M M M M M + M M M M M M M M M M M M M + M M M | 4 |
SKIN | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 216
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:40:05.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 0| 1| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 7| 7| S R R|
| 2| 2| 4| 4| 5| 7| 7| 7| 1| 1| 1| 1| 4| 4| 4| 0| 0| 0| 1| 1| 1| 2| 2| U V I|
50MG MS-2YR 30 30 | 5| 8| 8| 9| 0| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 7| 8| 9| 0| 1| 2| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + M | 46 |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 1 2.0|
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 2 1 1 2 1 1 | 13 1.3|
PERIPHERAL NERVE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
SPINAL CORD,THORACIC | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | M + + + + + + + + + + + + + + + + + + + + M + | 45 |
LUNG | + + + + + M + + + + + + + + + + + + + + + + + | 47 |
CONGESTION | | 1 3.0|
HYPERPLASIA,ALVEOLAR EPITHELIUM | 1 1 1 | 7 1.5|
INFILTRATION CELLULAR,HISTIOCYTIC | 4 | 3 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 2 2 2 2 1 1 2 4 2 3 1 2 1 3 3 1 | 37 2.0|
NOSE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 2.0|
INFLAMMATION | 1 3 | 2 2.0|
TRACHEA | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 | 29 1.1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 217
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:40:05.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 0| 1| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 7| 7| S R R|
| 2| 2| 4| 4| 5| 7| 7| 7| 1| 1| 1| 1| 4| 4| 4| 0| 0| 0| 1| 1| 1| 2| 2| U V I|
50MG MS-2YR 30 30 | 5| 8| 8| 9| 0| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 7| 8| 9| 0| 1| 2| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
INFLAMMATION | | 1 3.0|
LACRIMAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ATROPHY | 2 | 2 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 | 8 1.2|
VACUOLIZATION CYTOPLASMIC | | 1 2.0|
ZYMBAL'S GLAND | + + + + + + + + + + + + + + + + + M + + + + M | 45 |
INFLAMMATION | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
CONGESTION | 3 | 2 3.0|
FOCAL CELLULAR CHANGE | | 1 1.0|
INFARCT | | 1 4.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 1 1 2 1 2 2 1 2 1 3 2 1 2 2 3 | 42 1.5|
INFILTRATION CELLULAR,PLASMA CELL | | 1 1.0|
INFLAMMATION | | 1 3.0|
MINERALIZATION | | 1 1.0|
NEPHROPATHY | 1 | 4 1.2|
PIGMENTATION,RENAL TUBULE | | 1 1.0|
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + M + + + | 47 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 2 2 1 1 1 2 1 | 22 1.2|
INFLAMMATION | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 218
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:40:08.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 1| 1| 1| 1| 1| 1| 1| 1|
| 1| 1| 1| 1| 1| 1| 1| 1|
| 9| 9| 9| 9| 9| 9| 9| 9|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 0| 0| 0| 0| 0| 0| 1| 1| U V I|
100MG F120 DAYS 36 | 4| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + | 8 |
GALLBLADDER | + + + + + + + + | 8 |
INTESTINE LARGE | + + + + + + + + | 8 |
INTESTINE LARGE,CECUM | + + + + + + + + | 8 |
INTESTINE LARGE,COLON | + + + + + + + + | 8 |
INTESTINE LARGE,RECTUM | + + + + + + + + | 8 |
INTESTINE SMALL | + + + + + + + + | 8 |
INTESTINE SMALL,DUODENUM | + + + + + M + + | 7 |
INTESTINE SMALL,ILEUM | + + + + + + + + | 8 |
INTESTINE SMALL,JEJUNUM | + + + + + + + + | 8 |
LIVER | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 | 3 1.0|
NECROSIS | 1 1 1 1 1 | 5 1.0|
TENSION LIPOIDOSIS | X X X X | 4 |
PANCREAS | + + + + + + + + | 8 |
SALIVARY GLANDS | + + + + + + + + | 8 |
STOMACH | + + + + + + + + | 8 |
STOMACH,FORESTOMACH | + + + + + + + + | 8 |
STOMACH,GLANDULAR | + + + + + + + + | 8 |
TONGUE | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + M M + + | 6 |
BLOOD VESSEL,AORTA | + + + + M M + + | 6 |
HEART | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + | 8 |
ADRENAL GLAND,CORTEX | + + + + + + + + | 8 |
HYPERPLASIA,SPINDLE CELL | 1 1 1 | 3 1.0|
ADRENAL GLAND,MEDULLA | + + + + + + + + | 8 |
ISLETS, PANCREATIC | + + + + + + + + | 8 |
HYPERPLASIA | 1 | 1 1.0|
PARATHYROID GLAND | + + + + + + + M | 7 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 219
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:40:08.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 1| 1| 1| 1| 1| 1| 1| 1|
| 1| 1| 1| 1| 1| 1| 1| 1|
| 9| 9| 9| 9| 9| 9| 9| 9|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 0| 0| 0| 0| 0| 0| 1| 1| U V I|
100MG F120 DAYS 36 | 4| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
PITUITARY GLAND | + + + + + M + + | 7 |
THYROID GLAND | + + + + + + + + | 8 |
DEGENERATION | 1 | 1 1.0|
ULTIMOBRANCHIAL CYST | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + + M + + M M | 5 |
OVARY | + + + + + + + + | 8 |
UTERUS | + + + + + + + + | 8 |
VAGINA | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + | 8 |
LYMPH NODE | + + + + + + + + | 8 |
LYMPH NODE,MANDIBULAR | + + + + + + + + | 8 |
LYMPH NODE,MESENTERIC | + + + + + + + + | 8 |
HEMORRHAGE | 1 | 1 1.0|
SPLEEN | + + + + + + + + | 8 |
THYMUS | + + + + + + + + | 8 |
CYST | 1 | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + + + + + | 8 |
SKIN | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + | 8 |
BONE,FEMUR | + + + + + + + + | 8 |
BONE,STERNUM | + + + + + + + + | 8 |
SKELETAL MUSCLE | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 220
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:40:08.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 1| 1| 1| 1| 1| 1| 1| 1|
| 1| 1| 1| 1| 1| 1| 1| 1|
| 9| 9| 9| 9| 9| 9| 9| 9|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 0| 0| 0| 0| 0| 0| 1| 1| U V I|
100MG F120 DAYS 36 | 4| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
BRAIN | + + + + + + + + | 8 |
BRAIN,CEREBELLUM | + + + + + + + + | 8 |
BRAIN,CEREBRUM | + + + + + + + + | 8 |
PERIPHERAL NERVE | + + + + + + + + | 8 |
SPINAL CORD | + + + + + + + + | 8 |
SPINAL CORD,THORACIC | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + M M + + | 6 |
LUNG | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
INFLAMMATION | 2 | 1 2.0|
NOSE | + + + + + + + + | 8 |
MINERALIZATION,NASOLACRIMAL DUCT | 4 | 1 4.0|
TRACHEA | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + | 8 |
HARDERIAN GLAND | + + + + + + + + | 8 |
LACRIMAL GLAND | + + + + + + + + | 8 |
ZYMBAL'S GLAND | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + | 8 |
URINARY BLADDER | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 221
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:40:10.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 2| 2| 2| 2| 2| 2| 2| 2|
| 1| 1| 1| 1| 1| 1| 1| 1|
| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 2| 3| 3| 3| 3| 3| 3| 3| U V I|
100MG F210 DAYS 37 | 9| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + | 8 |
GALLBLADDER | + + + + + + + + | 8 |
INTESTINE LARGE | + + + + + + + + | 8 |
INTESTINE LARGE,CECUM | + + + + + + + + | 8 |
INTESTINE LARGE,COLON | + + + + + + + + | 8 |
INTESTINE LARGE,RECTUM | + + + + + + + + | 8 |
INTESTINE SMALL | + + + + + + + + | 8 |
INTESTINE SMALL,DUODENUM | + M + + + + + + | 7 |
INTESTINE SMALL,ILEUM | + + + + + + + + | 8 |
INTESTINE SMALL,JEJUNUM | + + + + + + + + | 8 |
LIVER | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 | 4 1.0|
NECROSIS | 1 1 1 1 1 1 | 6 1.0|
TENSION LIPOIDOSIS | X X X X X | 5 |
VACUOLIZATION CYTOPLASMIC | 1 1 1 2 1 2 1 | 7 1.2|
PANCREAS | + + + + + + + + | 8 |
SALIVARY GLANDS | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 2 1 | 3 1.3|
STOMACH | + + + + + + + + | 8 |
STOMACH,FORESTOMACH | + + + + + + + + | 8 |
HYPERKERATOSIS | 2 | 1 2.0|
STOMACH,GLANDULAR | + + + + + + + + | 8 |
TONGUE | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + M + + + + | 7 |
BLOOD VESSEL,AORTA | + + + M + + + + | 7 |
HEART | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + | 8 |
ADRENAL GLAND,CORTEX | + + + + + + + + | 8 |
DEGENERATION,FATTY | 3 | 1 3.0|
HYPERPLASIA,SPINDLE CELL | 1 2 1 1 2 1 1 | 7 1.2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 222
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:40:10.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 2| 2| 2| 2| 2| 2| 2| 2|
| 1| 1| 1| 1| 1| 1| 1| 1|
| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 2| 3| 3| 3| 3| 3| 3| 3| U V I|
100MG F210 DAYS 37 | 9| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
ADRENAL GLAND,MEDULLA | + M + + + + + + | 7 |
ISLETS, PANCREATIC | + + + + + + + + | 8 |
PARATHYROID GLAND | + M + M + + + + | 6 |
PITUITARY GLAND | + M + M + M M M | 3 |
THYROID GLAND | M M + + + + + + | 6 |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | M M + + M M + + | 4 |
OVARY | + + + + + + + + | 8 |
UTERUS | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
VAGINA | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + | 8 |
HYPERPLASIA | 2 | 1 2.0|
LYMPH NODE | + + + + + + + + | 8 |
LYMPH NODE,MANDIBULAR | + + + + + + + + | 8 |
HYPERPLASIA,LYMPHOID | 2 2 | 2 2.0|
LYMPH NODE,MESENTERIC | + + + + + + + + | 8 |
SPLEEN | + + + + + + + + | 8 |
HEMATOPOIETIC CELL PROLIFERATION | 3 | 1 3.0|
THYMUS | M + + + + + + + | 7 |
HEMORRHAGE | 2 | 1 2.0|
HYPERPLASIA,LYMPHOID,MEDULLA | 1 | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + M + + + + + | 7 |
SKIN | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 223
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:40:10.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 2| 2| 2| 2| 2| 2| 2| 2|
| 1| 1| 1| 1| 1| 1| 1| 1|
| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 2| 3| 3| 3| 3| 3| 3| 3| U V I|
100MG F210 DAYS 37 | 9| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + | 8 |
BONE,FEMUR | + + + + + + + + | 8 |
BONE,STERNUM | + + + + + + + + | 8 |
SKELETAL MUSCLE | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + | 8 |
BRAIN,CEREBELLUM | + + + + + + + + | 8 |
BRAIN,CEREBRUM | + + + + + + + + | 8 |
PERIPHERAL NERVE | + + + + + + + + | 8 |
SPINAL CORD | + + + + + + + + | 8 |
SPINAL CORD,THORACIC | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + M + + + M + M | 5 |
LUNG | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 | 3 1.0|
NOSE | + + + + + + + + | 8 |
TRACHEA | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + | 8 |
HARDERIAN GLAND | + + + + + + + + | 8 |
LACRIMAL GLAND | M + + + + + + + | 7 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 | 3 1.0|
ZYMBAL'S GLAND | + + M + + + M + | 6 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 | 4 1.0|
URINARY BLADDER | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 224
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:40:11.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 2| 2| 2| 2| 2| 2| 2| 2|
| 1| 1| 1| 1| 1| 1| 1| 1|
| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 2| 3| 3| 3| 3| 3| 3| 3| U V I|
100MG F210 DAYS 37 | 9| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 225
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:40:14.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 3| 3| 3| 3| 3| 3| 3|
| 9| 9| 9| 9| 9| 9| 9| 9|
| 2| 2| 2| 2| 2| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 4| 4| 5| 5| 5| 5| 5| 5| U V I|
100MG F392 DAYS 38 | 8| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + | 8 |
GALLBLADDER | + + + M M + + + | 6 |
INTESTINE LARGE | + + + + + + + + | 8 |
INTESTINE LARGE,CECUM | + + + + + + + + | 8 |
HYPERPLASIA,LYMPHOID | 2 | 1 2.0|
INTESTINE LARGE,COLON | + + + + + + + + | 8 |
INTESTINE LARGE,RECTUM | + M M + + + + + | 6 |
INTESTINE SMALL | + + + + + + + + | 8 |
INTESTINE SMALL,DUODENUM | + + + M + + + + | 7 |
INTESTINE SMALL,ILEUM | + + + + + + + + | 8 |
INTESTINE SMALL,JEJUNUM | + + + + + + + + | 8 |
LIVER | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 1 | 6 1.0|
NECROSIS | 1 1 1 | 3 1.0|
TENSION LIPOIDOSIS | X | 1 |
VACUOLIZATION CYTOPLASMIC | 1 1 1 | 3 1.0|
PANCREAS | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | 2 1.0|
SALIVARY GLANDS | + + + + + + + + | 8 |
ATROPHY | 3 | 1 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 2 2 1 | 7 1.4|
STOMACH | + + + + + + + + | 8 |
STOMACH,FORESTOMACH | + + + + + + + + | 8 |
HYPERKERATOSIS | 2 | 1 2.0|
STOMACH,GLANDULAR | + + + + + + + + | 8 |
TONGUE | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | M M + + + + + + | 6 |
BLOOD VESSEL,AORTA | M M + + + + + + | 6 |
HEART | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 226
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:40:14.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 3| 3| 3| 3| 3| 3| 3|
| 9| 9| 9| 9| 9| 9| 9| 9|
| 2| 2| 2| 2| 2| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 4| 4| 5| 5| 5| 5| 5| 5| U V I|
100MG F392 DAYS 38 | 8| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + | 8 |
ADRENAL GLAND,CORTEX | + + + + + + + + | 8 |
CONGESTION | 2 | 1 2.0|
HYPERPLASIA,SPINDLE CELL | 2 2 2 2 2 2 | 6 2.0|
VACUOLIZATION CYTOPLASMIC | 1 1 | 2 1.0|
ADRENAL GLAND,MEDULLA | + + + + + + + + | 8 |
ISLETS, PANCREATIC | + + + + + + + + | 8 |
PARATHYROID GLAND | + + M + + + M + | 6 |
PITUITARY GLAND | M + + M M + + + | 5 |
CYST | 2 | 1 2.0|
THYROID GLAND | + + M + + + M + | 6 |
ULTIMOBRANCHIAL CYST | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
CLITORAL GLAND | + + M M + + + + | 6 |
ATROPHY | 4 3 2 | 3 3.0|
OVARY | + + + + M + + + | 7 |
ATROPHY | X | 1 |
CYST,PERIOVARIAN TISSUE | X X | 2 |
HEMATOCYST | X | 1 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 1 2.0|
UTERUS | + + + + + + + + | 8 |
HYPERPLASIA,CYSTIC,ENDOMETRIUM | 2 2 2 | 3 2.0|
VAGINA | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + | 8 |
LYMPH NODE | + + + + + + + + | 8 |
LYMPH NODE,MANDIBULAR | + + + + + + + + | 8 |
HEMORRHAGE | 1 1 | 2 1.0|
HYPERPLASIA,LYMPHOID | 2 | 1 2.0|
LYMPH NODE,MESENTERIC | + + + + + + + + | 8 |
ATROPHY | 2 2 2 2 | 4 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 227
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:40:14.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 3| 3| 3| 3| 3| 3| 3|
| 9| 9| 9| 9| 9| 9| 9| 9|
| 2| 2| 2| 2| 2| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 4| 4| 5| 5| 5| 5| 5| 5| U V I|
100MG F392 DAYS 38 | 8| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
HYPERPLASIA,LYMPHOID | 2 | 1 2.0|
SPLEEN | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
THYMUS | + + + + + + + + | 8 |
CYST | 2 | 1 2.0|
HEMORRHAGE | 1 | 1 1.0|
HYPERPLASIA,LYMPHOID,MEDULLA | 2 2 2 1 1 1 | 6 1.5|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + + + + + + + | 8 |
SKIN | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + | 8 |
BONE,FEMUR | + + + + + + + + | 8 |
FIBROUS OSTEODYSTROPHY | 1 1 | 2 1.0|
BONE,STERNUM | + + + + + + + + | 8 |
SKELETAL MUSCLE | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + | 8 |
BRAIN,CEREBELLUM | + + + + + + + + | 8 |
BRAIN,CEREBRUM | + + + + + + + + | 8 |
MINERALIZATION,MULTIFOCAL,THALAMUS | 1 1 | 2 1.0|
PERIPHERAL NERVE | + + + + + + + + | 8 |
SPINAL CORD | + + + + + + + + | 8 |
SPINAL CORD,THORACIC | + + + + + + + + | 8 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + M + M + M M | 4 |
LUNG | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 2 1 1 1 | 7 1.1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211601 PAGE: 228
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/03/2000
PATHOLOGY REPORT 4 TIME: 15:40:14.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 3| 3| 3| 3| 3| 3| 3|
| 9| 9| 9| 9| 9| 9| 9| 9|
| 2| 2| 2| 2| 2| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| S E V|
FEMALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| S R R|
| 4| 4| 5| 5| 5| 5| 5| 5| U V I|
100MG F392 DAYS 38 | 8| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM
INFLAMMATION | 3 | 1 3.0|
NOSE | + + + + + + + + | 8 |
TRACHEA | + M + + + + M + | 6 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + | 8 |
HARDERIAN GLAND | + + + + + + + + | 8 |
LACRIMAL GLAND | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 1 1 1 | 5 1.0|
ZYMBAL'S GLAND | + M M + + + M + | 5 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + | 8 |
CYST,RENAL TUBULE | 1 | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 1 1 | 6 1.1|
URINARY BLADDER | + + + + + + + + | 8 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 1 1 1 2 | 6 1.3|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED