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NCTR Study 211701 Pathology Tables

NCTR EXP/TEST:   211701                                                                                      PAGE:    1
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:47.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 1| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 8|
                                            | 0| 3| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 8|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3|   S      M|
                                            | 5| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 5| 5| 6| 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 6|   U      O|
CONTROL A 2YR  1     1                      | 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| 8| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
GALLBLADDER                                 | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
INTESTINE LARGE                             | A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE LARGE,CECUM                       | A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE LARGE,COLON                       | A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE LARGE,RECTUM                      | A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE SMALL                             | A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE SMALL,DUODENUM                    | A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
  LYMPHOMA MALIGNANT                        |       X                          X                                        |          |
INTESTINE SMALL,ILEUM                       | A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
  LYMPHOMA MALIGNANT                        |                                  X                                        |          |
INTESTINE SMALL,JEJUNUM                     | A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
  LYMPHOMA MALIGNANT                        |                                  X                                        |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA,SINGLE             | X     X                                                  X        X  X    |          |
  HEPATOCELLULAR ADENOMA,TWO                |                                           X                               |          |
  HEPATOCELLULAR CARCINOMA,FOUR             |                                                                         X |          |
  HEPATOCELLULAR CARCINOMA,SINGLE           |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
PANCREAS                                    | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
STOMACH                                     | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
STOMACH,FORESTOMACH                         | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
STOMACH,GLANDULAR                           | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:    2
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:47.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 1| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 8|
                                            | 0| 3| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 8|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3|   S      M|
                                            | 5| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 5| 5| 6| 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 6|   U      O|
CONTROL A 2YR  1     1                      | 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| 8| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  M |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  M |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  M |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  CARCINOMA                                 |                                                                           |          |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
PITUITARY GLAND                             | +  M  M  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA,FOLLICULAR CELL                   |                                                                           |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
EPIDIDYMIS                                  | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
PREPUTIAL GLAND                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
PROSTATE                                    | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
SEMINAL VESICLE                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
TESTES                                      | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA,INTERSTITIAL CELL                 |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA,METASTATIC,SPLEEN         |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT,AXILLARY               |    X                                                                      |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |    X                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:    3
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:47.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 1| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 8|
                                            | 0| 3| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 8|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3|   S      M|
                                            | 5| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 5| 5| 6| 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 6|   U      O|
CONTROL A 2YR  1     1                      | 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| 8| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  LYMPHOMA MALIGNANT,RENAL                  |    X                                                                      |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA,METASTATIC,SPLEEN         |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X  X                                            X                      |          |
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X  X                          X                 X                      |          |
THYMUS                                      | +  +  +  +  +  +  M  +  +  +  M  +  +  M  M  +  +  +  M  M  +  +  M  M  M |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  M  M  M  M  M  +  +  M  +  M  M  M  M  M  M  M  M  M  M  M  M  M  M |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROMA                                   |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:    4
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:47.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 1| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 8|
                                            | 0| 3| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 8|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3|   S      M|
                                            | 5| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 5| 5| 6| 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 6|   U      O|
CONTROL A 2YR  1     1                      | 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| 8| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |          X           X     X                    X     X        X          |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA,TWO          |                                                                           |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                  X     X                                  |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                         X |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ZYMBAL'S GLAND                              | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
URINARY BLADDER                             | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:    5
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:55.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 0| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 8| 7| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|         S      M|
                                            | 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 5| 6| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9|         U      O|
CONTROL A 2YR  1     1                      | 0| 1| 9| 1| 2| 3| 4| 5| 6| 7| 8| 5| 8| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
GALLBLADDER                                 | A  A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
INTESTINE LARGE                             | A  A  A  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +       | 41       |
INTESTINE LARGE,CECUM                       | A  A  A  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +       | 41       |
INTESTINE LARGE,COLON                       | A  A  A  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +       | 41       |
INTESTINE LARGE,RECTUM                      | A  A  A  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +       | 41       |
INTESTINE SMALL                             | A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 42       |
INTESTINE SMALL,DUODENUM                    | A  A  A  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +       | 41       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
INTESTINE SMALL,ILEUM                       | A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 42       |
  LYMPHOMA MALIGNANT                        |                                     X                                     |         2|
INTESTINE SMALL,JEJUNUM                     | A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 42       |
  LYMPHOMA MALIGNANT                        |                                     X                                     |         2|
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA,SINGLE             | X  X                 X        X                             X             |        10|
  HEPATOCELLULAR ADENOMA,TWO                |                   X                                                       |         2|
  HEPATOCELLULAR CARCINOMA,FOUR             |                                                                           |         1|
  HEPATOCELLULAR CARCINOMA,SINGLE           |       X                                                        X  X       |         3|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
PANCREAS                                    | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
STOMACH                                     | A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
STOMACH,FORESTOMACH                         | A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
STOMACH,GLANDULAR                           | A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
TONGUE                                      | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:    6
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:55.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 0| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 8| 7| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|         S      M|
                                            | 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 5| 6| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9|         U      O|
CONTROL A 2YR  1     1                      | 0| 1| 9| 1| 2| 3| 4| 5| 6| 7| 8| 5| 8| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
ADRENAL GLAND,CORTEX                        | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
  LYMPHOMA MALIGNANT                        |                                     X                                     |         2|
ADRENAL GLAND,MEDULLA                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  CARCINOMA                                 |                X                                                          |         1|
PARATHYROID GLAND                           | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PITUITARY GLAND                             | +  A  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  M  +  +  +  +       | 42       |
THYROID GLAND                               | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  ADENOMA,FOLLICULAR CELL                   |          X                                                                |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
EPIDIDYMIS                                  | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PREPUTIAL GLAND                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PROSTATE                                    | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SEMINAL VESICLE                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
TESTES                                      | A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
  ADENOMA,INTERSTITIAL CELL                 |                                                                   X       |         1|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  HEMANGIOSARCOMA,METASTATIC,SPLEEN         | X                                                                         |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT,AXILLARY               |                                                                           |         1|
  LYMPHOMA MALIGNANT,LUMBAR                 |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:    7
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:55.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 0| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 8| 7| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|         S      M|
                                            | 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 5| 6| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9|         U      O|
CONTROL A 2YR  1     1                      | 0| 1| 9| 1| 2| 3| 4| 5| 6| 7| 8| 5| 8| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  LYMPHOMA MALIGNANT,RENAL                  |                                     X                                     |         2|
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
LYMPH NODE,MESENTERIC                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  HEMANGIOSARCOMA,METASTATIC,SPLEEN         | X                                                                         |         1|
  LYMPHOMA MALIGNANT                        |                                     X                                     |         4|
SPLEEN                                      | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  HEMANGIOSARCOMA                           | X                                                                         |         1|
  LYMPHOMA MALIGNANT                        |                                     X                                     |         5|
THYMUS                                      | +  M  M  +  +  +  +  M  +  +  +  +  M  +  +  M  +  M  M  M  M  M  +       | 29       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M       |  5       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  FIBROMA                                   |                                                                X          |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
BONE,FEMUR                                  | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
BONE,STERNUM                                | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SKELETAL MUSCLE                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
BRAIN,CEREBELLUM                            | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
BRAIN,CEREBRUM                              | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
PERIPHERAL NERVE                            | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
SPINAL CORD                                 | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:    8
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:55.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 0| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 8| 7| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|         S      M|
                                            | 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 5| 6| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9|         U      O|
CONTROL A 2YR  1     1                      | 0| 1| 9| 1| 2| 3| 4| 5| 6| 7| 8| 5| 8| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

LARYNX                                      | +  A  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |          X              X     X           X  X           X                |        12|
  ALVEOLAR/BRONCHIOLAR ADENOMA,TWO          |    X                                                                      |         1|
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                                                           |         2|
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
NOSE                                        | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
TRACHEA                                     | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
HARDERIAN GLAND                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  ADENOMA                                   |                X                 X        X                 X  X          |         5|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M       | 47       |
ZYMBAL'S GLAND                              | +  A  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
URINARY BLADDER                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:    9
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:58.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 3| 5| 7| 3| 2| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 3| 6| 5| 4| 8| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 5|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3|   S      M|
                                            | 6| 6| 6| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| 5| 6| 6| 8| 9| 9| 9| 9| 9| 9| 6|   U      O|
25 MG/KGA 2YR  2     2                      | 4| 6| 8| 4| 5| 6| 1| 2| 3| 4| 5| 6| 7| 8| 3| 7| 8| 9| 0| 1| 2| 3| 4| 5| 4|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +                                                        + |          |
GALLBLADDER                                 | +  +  +  +  +  +                                                        + |          |
INTESTINE LARGE                             | +  +  A  A  A  A                                                        A |          |
INTESTINE LARGE,CECUM                       | +  +  A  A  A  A                                                        A |          |
INTESTINE LARGE,COLON                       | +  +  A  A  A  A                                                        A |          |
INTESTINE LARGE,RECTUM                      | +  +  A  A  A  A                                                        A |          |
INTESTINE SMALL                             | +  +  A  A  +  A           +                                            A |          |
INTESTINE SMALL,DUODENUM                    | +  +  A  A  +  A           +                                            A |          |
  LYMPHOMA MALIGNANT                        |                            X                                              |          |
INTESTINE SMALL,ILEUM                       | +  +  A  A  A  A                                                        A |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
INTESTINE SMALL,JEJUNUM                     | +  +  A  A  A  A                                                        A |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOMA                                |                                              X                            |          |
  HEPATOCELLULAR ADENOMA,FOUR               |                                                                      X    |          |
  HEPATOCELLULAR ADENOMA,MULTIPLE           |             X                                                             |          |
  HEPATOCELLULAR ADENOMA,SINGLE             | X              X     X     X              X        X     X  X             |          |
  HEPATOCELLULAR ADENOMA,THREE              |                                                                           |          |
  HEPATOCELLULAR ADENOMA,TWO                |          X        X                          X                            |          |
  HEPATOCELLULAR CARCINOMA                  |       X                                                                   |          |
  HEPATOCELLULAR CARCINOMA,SINGLE           |                X  X              X                       X              X |          |
PANCREAS                                    | +  +  +  +  +  +                                                        + |          |
  CARCINOMA,DUCT                            |       X                                                                   |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
SALIVARY GLANDS                             | +  +  A  +  +  +                                                        + |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
STOMACH                                     | +  +  +  +  +  +                                                        + |          |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +                                                        + |          |
STOMACH,GLANDULAR                           | +  +  +  +  +  +                                                        + |          |
TONGUE                                      | +  +  +  +  +  +                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +                                                        + |          |
  CARCINOMA,METASTATIC,PANCREAS             |       X                                                                   |          |
HEART                                       | +  +  +  +  +  +                                                        + |          |
  CARCINOMA,METASTATIC,PANCREAS             |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   10
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:58.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 3| 5| 7| 3| 2| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 3| 6| 5| 4| 8| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 5|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3|   S      M|
                                            | 6| 6| 6| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| 5| 6| 6| 8| 9| 9| 9| 9| 9| 9| 6|   U      O|
25 MG/KGA 2YR  2     2                      | 4| 6| 8| 4| 5| 6| 1| 2| 3| 4| 5| 6| 7| 8| 3| 7| 8| 9| 0| 1| 2| 3| 4| 5| 4|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +                                                        + |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +                                                        + |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +                                                        + |          |
ISLETS, PANCREATIC                          | +  +  +  +  +  +                                                        + |          |
PARATHYROID GLAND                           | +  +  M  M  +  M                                                        + |          |
PITUITARY GLAND                             | M  +  +  +  +  +                                                        + |          |
THYROID GLAND                               | +  +  +  +  +  +                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +  +  +                                                        + |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
EPIDIDYMIS                                  | +  +  +  +  +  +                                                        + |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
PREPUTIAL GLAND                             | +  +  M  +  +  +                                                        + |          |
PROSTATE                                    | +  +  +  +  +  +                                                        + |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
SEMINAL VESICLE                             | +  +  +  +  +  +                                                        + |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
TESTES                                      | +  +  +  +  +  +                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +                                                        + |          |
LYMPH NODE                                  | +  +  +  +  +  +  +        +  +                    +                    + |          |
  HISTIOCYTIC SARCOMA,BRONCHIAL             |                                                                           |          |
  HISTIOCYTIC SARCOMA,RENAL                 |                                                                           |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |                               X                                           |          |
LYMPH NODE,MANDIBULAR                       | +  +  A  +  +  +                                                        + |          |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +           +  +                    +                    + |          |
  CARCINOMA,METASTATIC,PANCREAS             |       X                                                                   |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                            X  X                                           |          |
SPLEEN                                      | +  +  +  +  +  +  +        +  +           +        +     +              + |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                            X  X                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   11
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:58.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 3| 5| 7| 3| 2| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 3| 6| 5| 4| 8| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 5|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3|   S      M|
                                            | 6| 6| 6| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| 5| 6| 6| 8| 9| 9| 9| 9| 9| 9| 6|   U      O|
25 MG/KGA 2YR  2     2                      | 4| 6| 8| 4| 5| 6| 1| 2| 3| 4| 5| 6| 7| 8| 3| 7| 8| 9| 0| 1| 2| 3| 4| 5| 4|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

THYMUS                                      | +  M  M  +  +  M           +                                            M |          |
  LYMPHOMA MALIGNANT                        |                            X                                              |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M  M  M                                                        M |          |
SKIN                                        | +  +  +  +  +  +                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +                                                        + |          |
BONE,FEMUR                                  | +  +  +  +  +  +                                                        + |          |
BONE,STERNUM                                | +  +  +  +  +  +                                                        + |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +                                                        + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +                                                        + |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +                                                        + |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +                                                        + |          |
SPINAL CORD                                 | +  +  +  +  +  +                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +                                                        + |          |
LUNG                                        | +  +  +  +  +  +  +     +                                   +           + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |          X                                                  X             |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA,TWO          |                         X                                                 |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            | X  X                    X                                                 |          |
  CARCINOMA,METASTATIC,PANCREAS             |       X                                                                   |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
NOSE                                        | +  +  +  +  +  +                                                        + |          |
TRACHEA                                     | +  +  +  +  +  +                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   12
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:58.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 3| 5| 7| 3| 2| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 3| 6| 5| 4| 8| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 5|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3|   S      M|
                                            | 6| 6| 6| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| 5| 6| 6| 8| 9| 9| 9| 9| 9| 9| 6|   U      O|
25 MG/KGA 2YR  2     2                      | 4| 6| 8| 4| 5| 6| 1| 2| 3| 4| 5| 6| 7| 8| 3| 7| 8| 9| 0| 1| 2| 3| 4| 5| 4|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +                          +                             + |          |
HARDERIAN GLAND                             | +  +  +  +  +  +     +  +                 +           +                 + |          |
  ADENOMA                                   |                      X                    X           X                 X |          |
  CARCINOMA                                 |                         X                                                 |          |
LACRIMAL GLAND                              | +  +  A  +  +  +                                                        + |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
ZYMBAL'S GLAND                              | +  +  +  +  +  M                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +                                                        + |          |
  CARCINOMA,METASTATIC,PANCREAS             |       X                                                                   |          |
URINARY BLADDER                             | +  +  +  +  +  +                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   13
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:00.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 2| 1| 2| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 4| 7| 2| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|         S      M|
                                            | 6| 7| 7| 7| 8| 9| 9| 9| 9| 9| 9| 9| 9| 5| 5| 6| 9| 9| 9| 9| 9| 9| 9|         U      O|
25 MG/KGA 2YR  2     2                      | 9| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 7| 6| 7| 9| 2| 3| 4| 5| 6| 7| 8|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +                                                                | 11       |
GALLBLADDER                                 | +  +  +  M                                                                | 10       |
INTESTINE LARGE                             | +  +  +  A                                                                |  5       |
INTESTINE LARGE,CECUM                       | +  +  +  A                                                                |  5       |
INTESTINE LARGE,COLON                       | +  +  +  A                                                                |  5       |
INTESTINE LARGE,RECTUM                      | +  +  +  A                                                                |  5       |
INTESTINE SMALL                             | +  +  +  A                                                                |  7       |
INTESTINE SMALL,DUODENUM                    | +  +  +  A                                                                |  7       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
INTESTINE SMALL,ILEUM                       | +  +  +  A                                                                |  5       |
  HISTIOCYTIC SARCOMA                       |    X                                                                      |         1|
INTESTINE SMALL,JEJUNUM                     | +  +  +  A                                                                |  5       |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOMA                                |                                                                           |         1|
  HEPATOCELLULAR ADENOMA,FOUR               |                                                                           |         1|
  HEPATOCELLULAR ADENOMA,MULTIPLE           |                                                                           |         1|
  HEPATOCELLULAR ADENOMA,SINGLE             |                X        X  X                                              |        11|
  HEPATOCELLULAR ADENOMA,THREE              |       X                                                                   |         1|
  HEPATOCELLULAR ADENOMA,TWO                |             X                          X                                  |         5|
  HEPATOCELLULAR CARCINOMA                  |                                                                           |         1|
  HEPATOCELLULAR CARCINOMA,SINGLE           | X        X                 X                                X             |         9|
PANCREAS                                    | +  +  +  M                                                                | 10       |
  CARCINOMA,DUCT                            |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |    X                                                                      |         1|
SALIVARY GLANDS                             | +  +  +  +                                                                | 10       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
STOMACH                                     | +  +  +  A                                                                | 10       |
STOMACH,FORESTOMACH                         | +  +  +  A                                                                | 10       |
STOMACH,GLANDULAR                           | +  +  +  A                                                                | 10       |
TONGUE                                      | +  +  +  A                                                                | 10       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +                                                                | 11       |
  CARCINOMA,METASTATIC,PANCREAS             |                                                                           |         1|
HEART                                       | +  +  +  +                                                                | 11       |
  CARCINOMA,METASTATIC,PANCREAS             |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   14
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:00.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 2| 1| 2| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 4| 7| 2| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|         S      M|
                                            | 6| 7| 7| 7| 8| 9| 9| 9| 9| 9| 9| 9| 9| 5| 5| 6| 9| 9| 9| 9| 9| 9| 9|         U      O|
25 MG/KGA 2YR  2     2                      | 9| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 7| 6| 7| 9| 2| 3| 4| 5| 6| 7| 8|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +                                                                | 11       |
ADRENAL GLAND,CORTEX                        | +  +  +  +                                                                | 11       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
ADRENAL GLAND,MEDULLA                       | +  +  +  +                                                                | 11       |
ISLETS, PANCREATIC                          | +  +  +  M                                                                | 10       |
PARATHYROID GLAND                           | +  +  M  M                                                                |  6       |
PITUITARY GLAND                             | +  +  +  +                                                                | 10       |
THYROID GLAND                               | +  +  +  +                                                                | 11       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  A                                                                | 10       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
EPIDIDYMIS                                  | +  +  +  A                                                                | 10       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PREPUTIAL GLAND                             | +  +  +  A     +                                                          | 10       |
PROSTATE                                    | +  +  +  A                                                                | 10       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SEMINAL VESICLE                             | +  +  +  A                                         +                      | 11       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
TESTES                                      | +  +  +  +                                                                | 11       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  A                                                                | 10       |
LYMPH NODE                                  | +  +  +  +                                                                | 15       |
  HISTIOCYTIC SARCOMA,BRONCHIAL             |    X                                                                      |         1|
  HISTIOCYTIC SARCOMA,RENAL                 |       X                                                                   |         1|
  LYMPHOMA MALIGNANT,LUMBAR                 |                                                                           |         1|
LYMPH NODE,MANDIBULAR                       | +  +  +  +                                                                | 10       |
LYMPH NODE,MESENTERIC                       | +  +  +  A                                                                | 13       |
  CARCINOMA,METASTATIC,PANCREAS             |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |    X  X                                                                   |         2|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
SPLEEN                                      | +  +  +  A                                                                | 16       |
  HISTIOCYTIC SARCOMA                       |       X                                                                   |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   15
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:00.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 2| 1| 2| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 4| 7| 2| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|         S      M|
                                            | 6| 7| 7| 7| 8| 9| 9| 9| 9| 9| 9| 9| 9| 5| 5| 6| 9| 9| 9| 9| 9| 9| 9|         U      O|
25 MG/KGA 2YR  2     2                      | 9| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 7| 6| 7| 9| 2| 3| 4| 5| 6| 7| 8|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

THYMUS                                      | M  M  +  M                                                     +          |  6       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M                                                                |  0       |
SKIN                                        | +  +  +  A                                                                | 10       |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +                                                                | 11       |
BONE,FEMUR                                  | +  +  +  +                                                                | 11       |
BONE,STERNUM                                | +  +  +  +                                                                | 11       |
SKELETAL MUSCLE                             | +  +  +  A                                                                | 10       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  A                                                                | 10       |
BRAIN,CEREBELLUM                            | +  +  +  A                                                                | 10       |
BRAIN,CEREBRUM                              | +  +  +  A                                                                | 10       |
PERIPHERAL NERVE                            | +  +  +  A                                                                | 10       |
SPINAL CORD                                 | +  +  +  A                                                                | 10       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +                                                                | 11       |
LUNG                                        | +  +  +  +  +              +        +                 +        +  +       | 20       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                            X                          X        X  X       |         6|
  ALVEOLAR/BRONCHIOLAR ADENOMA,TWO          |             X                                                             |         2|
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                     X                                     |         4|
  CARCINOMA,METASTATIC,PANCREAS             |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
NOSE                                        | +  +  +  +                                                                | 11       |
TRACHEA                                     | +  +  +  A                                                                | 10       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   16
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:00.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 2| 1| 2| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 4| 7| 2| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|         S      M|
                                            | 6| 7| 7| 7| 8| 9| 9| 9| 9| 9| 9| 9| 9| 5| 5| 6| 9| 9| 9| 9| 9| 9| 9|         U      O|
25 MG/KGA 2YR  2     2                      | 9| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 7| 6| 7| 9| 2| 3| 4| 5| 6| 7| 8|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  A                                                                | 11       |
HARDERIAN GLAND                             | +  +  +  A           +                    +                               | 16       |
  ADENOMA                                   |                      X                    X                               |         6|
  CARCINOMA                                 |                                                                           |         1|
LACRIMAL GLAND                              | +  +  +  +                                                                | 10       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
ZYMBAL'S GLAND                              | +  +  +  A                                                                |  9       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  A                                                                | 10       |
  CARCINOMA,METASTATIC,PANCREAS             |                                                                           |         1|
URINARY BLADDER                             | +  +  +  A                                                                | 10       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   17
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:04.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 5| 5| 8| 2| 2| 4| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 2| 2| 1| 8| 9| 7| 5| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 6| 6| 7| 7| 7| 8| 9| 0| 0| 0| 0| 0| 0| 5| 6| 9| 9| 9| 9| 0| 0| 0| 0| 6|   U      O|
50 MG/KGA 2YR  3     3                      | 5| 5| 9| 2| 3| 8| 1| 9| 0| 1| 2| 3| 4| 5| 4| 9| 6| 7| 8| 9| 0| 1| 2| 3| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +                                                     + |          |
GALLBLADDER                                 | +  +  +  +  +  +  +                                                     + |          |
INTESTINE LARGE                             | +  A  A  A  A  A  +                                                     A |          |
INTESTINE LARGE,CECUM                       | +  A  A  A  A  A  +                                                     A |          |
INTESTINE LARGE,COLON                       | +  A  A  A  A  A  +                                                     A |          |
INTESTINE LARGE,RECTUM                      | +  A  A  A  A  A  +                                                     A |          |
INTESTINE SMALL                             | +  A  A  A  A  A  +        +                                            A |          |
INTESTINE SMALL,DUODENUM                    | +  A  A  A  A  A  +                                                     A |          |
INTESTINE SMALL,ILEUM                       | +  A  A  A  A  A  +        +                                            A |          |
  LYMPHOMA MALIGNANT                        |                            X                                              |          |
INTESTINE SMALL,JEJUNUM                     | +  A  A  A  A  A  +                                                     A |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  CARCINOMA,BILE DUCT                       |                X                                                          |          |
  HEPATOCELLULAR ADENOMA,MULTIPLE           |                                  X                                        |          |
  HEPATOCELLULAR ADENOMA,SINGLE             |                               X                                         X |          |
  HEPATOCELLULAR ADENOMA,THREE              |                                                    X                 X    |          |
  HEPATOCELLULAR ADENOMA,TWO                |                      X                                                    |          |
  HEPATOCELLULAR CARCINOMA,SINGLE           |                X                                                        X |          |
  HEPATOCELLULAR CARCINOMA,THREE            |          X                                                           X    |          |
  HEPATOCELLULAR CARCINOMA,TWO              |             X                                                             |          |
  LYMPHOMA MALIGNANT                        |    X                                   X                                  |          |
MESENTERY                                   |       +                                                                   |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
PANCREAS                                    | +  +  M  +  +  +  +                                                     + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
  NEOPLASM NOS                              |                X                                                          |          |
SALIVARY GLANDS                             | +  +  +  A  +  +  +                                                     + |          |
STOMACH                                     | +  +  +  +  +  +  +                                                     + |          |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +                                                     + |          |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +                                                     + |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
TONGUE                                      | +  +  +  +  +  +  +                                                     + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +                                                     + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   18
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:04.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 5| 5| 8| 2| 2| 4| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 2| 2| 1| 8| 9| 7| 5| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 6| 6| 7| 7| 7| 8| 9| 0| 0| 0| 0| 0| 0| 5| 6| 9| 9| 9| 9| 0| 0| 0| 0| 6|   U      O|
50 MG/KGA 2YR  3     3                      | 5| 5| 9| 2| 3| 8| 1| 9| 0| 1| 2| 3| 4| 5| 4| 9| 6| 7| 8| 9| 0| 1| 2| 3| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM

HEART                                       | +  +  +  +  +  +  +                                                     + |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +                                                     + |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +                                                     + |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +                                                     + |          |
ISLETS, PANCREATIC                          | +  +  M  +  +  +  +                                                     + |          |
PARATHYROID GLAND                           | M  M  M  +  +  +  M                                                     + |          |
PITUITARY GLAND                             | +  +  +  +  +  M  M                                                     + |          |
  ADENOMA,PARS DISTALIS                     |                                                                           |          |
THYROID GLAND                               | +  +  +  +  +  +  M                                                     + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  M  A  +  +  +  +                                                  + |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
EPIDIDYMIS                                  | +  +  +  A  +  +  +                                                  +  + |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
  HISTIOCYTIC SARCOMA                       |                                                                      X    |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
PREPUTIAL GLAND                             | +  +  +  M  +  +  +              +              +                       + |          |
PROSTATE                                    | +  +  +  +  +  +  +                                                     + |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
SEMINAL VESICLE                             | +  +  +  M  +  +  +  +                                                  + |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
TESTES                                      | +  +  +  A  +  +  +                                                     + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   19
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:04.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 5| 5| 8| 2| 2| 4| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 2| 2| 1| 8| 9| 7| 5| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 6| 6| 7| 7| 7| 8| 9| 0| 0| 0| 0| 0| 0| 5| 6| 9| 9| 9| 9| 0| 0| 0| 0| 6|   U      O|
50 MG/KGA 2YR  3     3                      | 5| 5| 9| 2| 3| 8| 1| 9| 0| 1| 2| 3| 4| 5| 4| 9| 6| 7| 8| 9| 0| 1| 2| 3| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +                                                     + |          |
LYMPH NODE                                  | +  +  +  +  +  +  +        +     +     +                    +           + |          |
  SARCOMA,METASTATIC,UNCERTAIN PRIMARY SITE |                                                                           |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  A  +  +  +                                                     + |          |
  LYMPHOMA MALIGNANT                        | X  X  X                                                                   |          |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +        +     +     +                    +           + |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X  X                    X           X                                  |          |
SPLEEN                                      | +  +  +  +  +  A  +  +                 +                 +              + |          |
  HEMANGIOSARCOMA                           |                                                                           |          |
  LYMPHOMA MALIGNANT                        | X  X                                   X                                  |          |
THYMUS                                      | +  M  +  M  M  +  M                                                     M |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
  LYMPHOMA MALIGNANT                        | X     X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M  M  M  M                                                     M |          |
SKIN                                        | +  M  +  +  +  +  +                                                     + |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +                                                     + |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +                                                     + |          |
BONE,STERNUM                                | +  +  +  +  +  +  +                                                     + |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +                                                     + |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
  RHABDOMYOSARCOMA                          |                   X                                                       |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  A  +  +  +                                                     + |          |
BRAIN,CEREBELLUM                            | +  +  +  A  +  +  +                                                     + |          |
BRAIN,CEREBRUM                              | +  +  +  A  +  +  +                                                     + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   20
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:04.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 5| 5| 8| 2| 2| 4| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 2| 2| 1| 8| 9| 7| 5| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 6| 6| 7| 7| 7| 8| 9| 0| 0| 0| 0| 0| 0| 5| 6| 9| 9| 9| 9| 0| 0| 0| 0| 6|   U      O|
50 MG/KGA 2YR  3     3                      | 5| 5| 9| 2| 3| 8| 1| 9| 0| 1| 2| 3| 4| 5| 4| 9| 6| 7| 8| 9| 0| 1| 2| 3| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM

  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +                                                     + |          |
SPINAL CORD                                 | +  +  +  A  +  +  +                                                     + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +                                                     + |          |
LUNG                                        | +  +  +  +  +  +  +                             +                 +     + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                 X                 X       |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA,TWO          |                                                                           |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                                                           |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER,|             X                                                           X |          |
      MULTIPLE                              |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
NOSE                                        | +  +  +  +  +  +  +                                                     + |          |
  CARCINOMA                                 |                                                                           |          |
TRACHEA                                     | +  +  +  +  +  +  +                                                     + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +                                                     + |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +                             +                       + |          |
  ADENOMA                                   |                                                 X                         |          |
  LYMPHOMA MALIGNANT,BILATERAL              |    X                                                                      |          |
LACRIMAL GLAND                              | +  +  +  A  +  +  +                                                     + |          |
ZYMBAL'S GLAND                              | +  +  M  +  +  +  M                                                     + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +                                                     + |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
URINARY BLADDER                             | +  +  +  +  +  +  +                                                     + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   21
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:06.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 2| 3| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 9| 7| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 6| 7| 7| 8| 9| 9| 0| 0| 0| 0| 0| 0| 0| 0| 7| 7| 9| 0| 0| 0| 0| 0| 0|         U      O|
50 MG/KGA 2YR  3     3                      | 7| 6| 7| 0| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 0| 1| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  A  +  +                                                                | 11       |
GALLBLADDER                                 | A  A  +  +                                                                | 10       |
INTESTINE LARGE                             | A  A  +  +                                                                |  4       |
INTESTINE LARGE,CECUM                       | A  A  +  +                                                                |  4       |
INTESTINE LARGE,COLON                       | A  A  +  +                                                                |  4       |
INTESTINE LARGE,RECTUM                      | A  A  +  +                                                                |  4       |
INTESTINE SMALL                             | A  A  +  +                                                                |  5       |
INTESTINE SMALL,DUODENUM                    | A  A  +  +                                                                |  4       |
INTESTINE SMALL,ILEUM                       | A  A  +  +                                                                |  5       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
INTESTINE SMALL,JEJUNUM                     | A  A  +  +                                                                |  4       |
LIVER                                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  CARCINOMA,BILE DUCT                       |                                                                           |         1|
  HEPATOCELLULAR ADENOMA,MULTIPLE           |                                                                           |         1|
  HEPATOCELLULAR ADENOMA,SINGLE             |       X     X     X        X           X                 X  X             |         9|
  HEPATOCELLULAR ADENOMA,THREE              |                                                                           |         2|
  HEPATOCELLULAR ADENOMA,TWO                |                         X     X     X                 X                   |         5|
  HEPATOCELLULAR CARCINOMA,SINGLE           | X                    X        X        X     X                            |         7|
  HEPATOCELLULAR CARCINOMA,THREE            |                                                                           |         2|
  HEPATOCELLULAR CARCINOMA,TWO              |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
MESENTERY                                   |                                                                           |  1       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PANCREAS                                    | A  A  +  +                                                                |  9       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
  NEOPLASM NOS                              |                                                                           |         1|
SALIVARY GLANDS                             | +  A  +  +                                                                | 10       |
STOMACH                                     | A  A  +  +                                                                | 10       |
STOMACH,FORESTOMACH                         | A  A  +  +                                                                | 10       |
STOMACH,GLANDULAR                           | A  A  +  +                                                                | 10       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
TONGUE                                      | +  A  +  +                                                                | 11       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  A  +  +                                                                | 11       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   22
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:06.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 2| 3| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 9| 7| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 6| 7| 7| 8| 9| 9| 0| 0| 0| 0| 0| 0| 0| 0| 7| 7| 9| 0| 0| 0| 0| 0| 0|         U      O|
50 MG/KGA 2YR  3     3                      | 7| 6| 7| 0| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 0| 1| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM

HEART                                       | +  A  +  +                                                                | 11       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | A  A  +  +                                                                | 10       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
ADRENAL GLAND,CORTEX                        | A  A  +  +                                                                | 10       |
ADRENAL GLAND,MEDULLA                       | A  A  +  +                                                                | 10       |
ISLETS, PANCREATIC                          | +  +  +  +                                                                | 11       |
PARATHYROID GLAND                           | +  A  M  +                                                                |  6       |
PITUITARY GLAND                             | A  A  +  +                 +                                              |  9       |
  ADENOMA,PARS DISTALIS                     |                            X                                              |         1|
THYROID GLAND                               | +  A  +  +                                                                | 10       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  A  +  +                                                                | 10       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
EPIDIDYMIS                                  | +  A  +  +                                                                | 11       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
PREPUTIAL GLAND                             | +  A  A  +                                                                | 11       |
PROSTATE                                    | +  A  +  +                                                                | 11       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
SEMINAL VESICLE                             | +  A  +  +                 +           +                       +          | 14       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
TESTES                                      | +  A  +  +                                                                | 10       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   23
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:06.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 2| 3| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 9| 7| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 6| 7| 7| 8| 9| 9| 0| 0| 0| 0| 0| 0| 0| 0| 7| 7| 9| 0| 0| 0| 0| 0| 0|         U      O|
50 MG/KGA 2YR  3     3                      | 7| 6| 7| 0| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 0| 1| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | A  A  +  +                                                                | 10       |
LYMPH NODE                                  | A  A  +  +                             +     +           +                | 17       |
  SARCOMA,METASTATIC,UNCERTAIN PRIMARY SITE |                                                          X                |         1|
LYMPH NODE,MANDIBULAR                       | M  A  +  +                                                                |  9       |
  LYMPHOMA MALIGNANT                        |                                                                           |         3|
LYMPH NODE,MESENTERIC                       | A  A  +  +                             +     +                            | 16       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                              X                            |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         4|
SPLEEN                                      | A  +  +  +              +  +     +              +                         | 17       |
  HEMANGIOSARCOMA                           |    X                             X                                        |         2|
  LYMPHOMA MALIGNANT                        |                                                                           |         3|
THYMUS                                      | M  M  M  +                                                                |  4       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M                                                                |  0       |
SKIN                                        | +  A  +  +                                                                | 10       |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +                                                                | 12       |
BONE,FEMUR                                  | +  +  +  +                                                                | 12       |
BONE,STERNUM                                | +  +  +  +                                                                | 12       |
SKELETAL MUSCLE                             | +  A  +  +                                                                | 11       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
  RHABDOMYOSARCOMA                          |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  A  A  +                                                                |  9       |
BRAIN,CEREBELLUM                            | +  A  A  +                                                                |  9       |
BRAIN,CEREBRUM                              | +  A  A  +                                                                |  9       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   24
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:06.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 2| 3| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 9| 7| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 6| 7| 7| 8| 9| 9| 0| 0| 0| 0| 0| 0| 0| 0| 7| 7| 9| 0| 0| 0| 0| 0| 0|         U      O|
50 MG/KGA 2YR  3     3                      | 7| 6| 7| 0| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 0| 1| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM

  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PERIPHERAL NERVE                            | +  A  +  +                                                                | 11       |
SPINAL CORD                                 | +  A  A  +                                                                |  9       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  A  +  +                                                                | 11       |
LUNG                                        | +  A  +  +  +                                            +  +             | 16       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                          X                |         3|
  ALVEOLAR/BRONCHIOLAR ADENOMA,TWO          |       X                                                                   |         1|
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |             X                                                             |         1|
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER,|                                                                           |         2|
      MULTIPLE                              |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
NOSE                                        | +  +  +  +                                                                | 12       |
  CARCINOMA                                 |       X                                                                   |         1|
TRACHEA                                     | +  A  +  +                                                                | 11       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  A  +  +                                                                | 11       |
HARDERIAN GLAND                             | +  A  +  +                                                                | 12       |
  ADENOMA                                   |       X                                                                   |         2|
  LYMPHOMA MALIGNANT,BILATERAL              |                                                                           |         1|
LACRIMAL GLAND                              | +  A  +  +                                                                | 10       |
ZYMBAL'S GLAND                              | M  A  M  +                                                                |  7       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | A  A  +  +                                                                | 10       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
URINARY BLADDER                             | +  A  +  +                                                                | 11       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   25
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:16.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 2| 6| 1| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 0| 2| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 6| 6| 7| 0| 0| 0| 0| 1| 1| 1| 1| 5| 5| 7| 7| 0| 0| 0| 0| 0| 0| 1| 1| 1| 6|   U      O|
100MG/KGA 2YR  4     4                      | 2| 7| 1| 6| 7| 8| 9| 0| 1| 2| 3| 6| 7| 0| 1| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
GALLBLADDER                                 | M  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |    X                                                                      |          |
INTESTINE LARGE                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE LARGE,CECUM                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
  LYMPHOMA MALIGNANT                        |                                                             X             |          |
INTESTINE LARGE,COLON                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE LARGE,RECTUM                      | M  A  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  A |          |
INTESTINE SMALL                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
INTESTINE SMALL,DUODENUM                    | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE SMALL,ILEUM                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
  ADENOCARCINOMA                            |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                  X              X                         |          |
INTESTINE SMALL,JEJUNUM                     | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA,SINGLE             |       X                             X     X           X  X        X       |          |
  HEPATOCELLULAR ADENOMA,THREE              |                                                                           |          |
  HEPATOCELLULAR ADENOMA,TWO                |                X                             X  X                         |          |
  HEPATOCELLULAR CARCINOMA,SINGLE           | X  X  X     X     X                                                       |          |
  HEPATOCELLULAR CARCINOMA,TWO              |                                           X                               |          |
  HISTIOCYTIC SARCOMA                       |                                           X                               |          |
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
STOMACH                                     | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
STOMACH,FORESTOMACH                         | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
STOMACH,GLANDULAR                           | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER,|    X                                                                      |          |
      AORTA                                 |                                                                           |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |    X  X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   26
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:16.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 2| 6| 1| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 0| 2| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 6| 6| 7| 0| 0| 0| 0| 1| 1| 1| 1| 5| 5| 7| 7| 0| 0| 0| 0| 0| 0| 1| 1| 1| 6|   U      O|
100MG/KGA 2YR  4     4                      | 2| 7| 1| 6| 7| 8| 9| 0| 1| 2| 3| 6| 7| 0| 1| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  + |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  M  +  +  +  +  + |          |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  M  +  +  +  +  + |          |
PITUITARY GLAND                             | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENERAL BODY SYSTEM

TISSUE NOS                                  |       +                                                                 + |          |
  HEMANGIOSARCOMA                           |                                                                         X |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER,|       X                                                                   |          |
      MEDIASTINUM                           |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
EPIDIDYMIS                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT,UNILATERAL             |                                                             X             |          |
  SCHWANNOMA BENIGN                         |                                              X                            |          |
PENIS                                       |                                                                         + |          |
PREPUTIAL GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PROSTATE                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |    X                                                                      |          |
SEMINAL VESICLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TESTES                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA,INTERSTITIAL CELL                 |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT,INGUINAL               |                                                             X             |          |
LYMPH NODE,MANDIBULAR                       | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                  X                          X             |          |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   27
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:17.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 2| 6| 1| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 0| 2| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 6| 6| 7| 0| 0| 0| 0| 1| 1| 1| 1| 5| 5| 7| 7| 0| 0| 0| 0| 0| 0| 1| 1| 1| 6|   U      O|
100MG/KGA 2YR  4     4                      | 2| 7| 1| 6| 7| 8| 9| 0| 1| 2| 3| 6| 7| 0| 1| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  HEMANGIOSARCOMA                           |                                                                         X |          |
  LYMPHOMA MALIGNANT                        |                                  X              X           X             |          |
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                                                                         X |          |
  LYMPHOMA MALIGNANT                        |                                  X                          X             |          |
THYMUS                                      | +  +  M  +  +  M  +  M  +  +  +  M  +  +  M  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |    X                                                                      |          |
  LYMPHOMA MALIGNANT                        |                                                             X             |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  +  M  +  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M |          |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  KERATOACANTHOMA                           |                                        X                                  |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                                                                         X |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  + |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                X                          X                 X           X |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   28
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:17.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 2| 6| 1| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 0| 2| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 6| 6| 7| 0| 0| 0| 0| 1| 1| 1| 1| 5| 5| 7| 7| 0| 0| 0| 0| 0| 0| 1| 1| 1| 6|   U      O|
100MG/KGA 2YR  4     4                      | 2| 7| 1| 6| 7| 8| 9| 0| 1| 2| 3| 6| 7| 0| 1| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

  ALVEOLAR/BRONCHIOLAR ADENOMA,TWO          |                         X                                                 |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                                    X                 X    |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |    X  X                                                                   |          |
  LYMPHOMA MALIGNANT                        |                                                             X             |          |
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT,UNILATERAL             |                                                                           |          |
HARDERIAN GLAND                             | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                                                                           |          |
LACRIMAL GLAND                              | +  M  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   29
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:25.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 5| 7| 7| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1|         U      O|
100MG/KGA 2YR  4     4                      | 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 9| 2| 3| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
GALLBLADDER                                 | +  +  +  +  +  +  +  +  +  +  +  M  M  +  +  +  +  +  +  +  +  +  +       | 44       |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         1|
INTESTINE LARGE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
INTESTINE LARGE,COLON                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  ADENOCARCINOMA                            |                                           X                               |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA,SINGLE             |       X                          X              X                 X       |        10|
  HEPATOCELLULAR ADENOMA,THREE              |                                                    X                      |         1|
  HEPATOCELLULAR ADENOMA,TWO                |    X                          X                             X             |         6|
  HEPATOCELLULAR CARCINOMA,SINGLE           |                                                       X                   |         6|
  HEPATOCELLULAR CARCINOMA,TWO              |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                     X                                     |         1|
STOMACH                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER,|                                                                           |         1|
      AORTA                                 |                                                                           |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   30
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:25.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 5| 7| 7| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1|         U      O|
100MG/KGA 2YR  4     4                      | 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 9| 2| 3| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +       | 46       |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +       | 46       |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +       | 45       |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PARATHYROID GLAND                           | +  +  +  M  M  +  +  +  +  +  M  +  +  +  M  +  +  +  +  +  +  +  +       | 42       |
PITUITARY GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +       | 46       |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
GENERAL BODY SYSTEM

TISSUE NOS                                  |                                                                           |  2       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER,|                                                                           |         1|
      MEDIASTINUM                           |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
EPIDIDYMIS                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT,UNILATERAL             |                                                                           |         1|
  SCHWANNOMA BENIGN                         |                                                                           |         1|
PENIS                                       |                                                                           |  1       |
PREPUTIAL GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PROSTATE                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         1|
SEMINAL VESICLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TESTES                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ADENOMA,INTERSTITIAL CELL                 |                                                             X             |         1|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT,INGUINAL               |                                                                           |         1|
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  M  M  +  +  +  +  +  +  +  +       | 45       |
  LYMPHOMA MALIGNANT                        |                                     X                                     |         3|
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   31
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:25.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 5| 7| 7| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1|         U      O|
100MG/KGA 2YR  4     4                      | 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 9| 2| 3| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  HEMANGIOSARCOMA                           |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                     X                                     |         4|
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA                           |                                        X                                  |         2|
  LYMPHOMA MALIGNANT                        |                                     X                                     |         3|
THYMUS                                      | +  M  +  M  +  +  +  M  +  M  +  M  +  +  M  +  +  +  M  +  +  M  +       | 35       |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                     X                                     |         2|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M       |  2       |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  KERATOACANTHOMA                           |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                     X                                     |         1|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |       X                                   X        X  X     X             |         9|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   32
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:25.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 5| 7| 7| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1|         U      O|
100MG/KGA 2YR  4     4                      | 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 9| 2| 3| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

  ALVEOLAR/BRONCHIOLAR ADENOMA,TWO          |                               X                                           |         2|
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                              X                            |         3|
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         2|
  LYMPHOMA MALIGNANT                        |                                     X                                     |         2|
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT,UNILATERAL             |                                     X                                     |         1|
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  ADENOMA                                   |                   X                                X  X  X        X       |         5|
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                     X                                     |         1|
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                     X                                     |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   33
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:26.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 2| 2| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3|                                          S      M|
                                            | 0| 1| 1| 3| 3| 3| 1| 1| 1| 3| 3| 3|                                          U      O|
CONTROL A 64WK 5     5                      | 9| 0| 1| 4| 5| 6| 1| 2| 3| 5| 6| 7|                                          E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +                                        | 12       |
  HEPATOCELLULAR ADENOMA,SINGLE             | X                       X                                                 |         2|
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   34
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:26.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 2| 2| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3|                                          S      M|
                                            | 1| 1| 1| 3| 3| 3| 1| 1| 1| 3| 3| 4|                                          U      O|
25MG/KG A 64W 6      6                      | 2| 3| 4| 7| 8| 9| 4| 5| 6| 8| 9| 0|                                          E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +                                        | 12       |
  HEPATOCELLULAR ADENOMA,SINGLE             |          X     X                                                          |         2|
  HEPATOCELLULAR CARCINOMA,SINGLE           |             X                                                             |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   35
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:26.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 2| 2| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3|                                          S      M|
                                            | 1| 1| 1| 4| 4| 4| 1| 1| 1| 4| 4| 4|                                          U      O|
50 MG/KGA 64W  7     7                      | 5| 6| 7| 0| 1| 2| 7| 8| 9| 1| 2| 3|                                          E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +                                        | 12       |
  HEPATOCELLULAR ADENOMA,SINGLE             |          X  X                                                             |         2|
  HEPATOCELLULAR ADENOMA,TWO                |                X                                                          |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   36
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:27.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 2| 2| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3|                                          S      M|
                                            | 1| 1| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4|                                          U      O|
100MG/KGA 64W  8     8                      | 8| 9| 0| 3| 4| 5| 0| 1| 2| 4| 5| 6|                                          E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +                                        | 12       |
  HEPATOCELLULAR ADENOMA,SINGLE             |    X                                                                      |         1|
  HEPATOCELLULAR CARCINOMA,SINGLE           | X              X                                                          |         2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   37
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:33.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
                                            | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 4|
                                            | 3| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 8| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 5| 5| 7| 7| 1| 1| 1| 1| 1| 1| 1| 2| 2| 0|   U      O|
CONTROL R 2YR 10    10                      | 0| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 5| 8| 2| 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  + |          |
GALLBLADDER                                 | +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +  +  +  +  M  M  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,COLON                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |       X                                                                   |          |
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X                                                       |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA,SINGLE             |                                        X  X  X           X                |          |
  HEPATOCELLULAR ADENOMA,TWO                |                                                                           |          |
  HEPATOCELLULAR CARCINOMA,SINGLE           |       X                                                                   |          |
  HISTIOCYTIC SARCOMA                       | X                 X                                                       |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   38
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:33.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
                                            | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 4|
                                            | 3| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 8| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 5| 5| 7| 7| 1| 1| 1| 1| 1| 1| 1| 2| 2| 0|   U      O|
CONTROL R 2YR 10    10                      | 0| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 5| 8| 2| 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  M  +  +  +  +  M  M |          |
PITUITARY GLAND                             | +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  + |          |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
EPIDIDYMIS                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PREPUTIAL GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PROSTATE                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
SEMINAL VESICLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TESTES                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |                                           X                               |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
LYMPH NODE,MESENTERIC                       | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X                                                     X |          |
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |             X                                                             |          |
  LYMPHOMA MALIGNANT                        |                   X                       X                             X |          |
THYMUS                                      | +  +  M  +  +  +  +  +  +  +  +  M  M  +  +  +  +  +  +  +  +  +  +  M  M |          |
  LYMPHOMA MALIGNANT                        |                   X                                                       |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M |          |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |             X                                                             |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   39
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:33.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
                                            | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 4|
                                            | 3| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 8| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 5| 5| 7| 7| 1| 1| 1| 1| 1| 1| 1| 2| 2| 0|   U      O|
CONTROL R 2YR 10    10                      | 0| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 5| 8| 2| 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  M |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                      X  X                 X           X           X  X    |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                                                           |          |
  HISTIOCYTIC SARCOMA                       | X                                                                         |          |
  LYMPHOMA MALIGNANT                        |                                                                         X |          |
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                                  X           X                            |          |
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ZYMBAL'S GLAND                              | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   40
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:33.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
                                            | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 4|
                                            | 3| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 8| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 5| 5| 7| 7| 1| 1| 1| 1| 1| 1| 1| 2| 2| 0|   U      O|
CONTROL R 2YR 10    10                      | 0| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 5| 8| 2| 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   41
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:39.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 1| 1| 2| 2| 2| 2| 2| 2| 2| 6| 6| 7| 7| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2|         U      O|
CONTROL R 2YR 10    10                      | 8| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 4| 5| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
GALLBLADDER                                 | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE LARGE                             | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
INTESTINE LARGE,CECUM                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
INTESTINE LARGE,COLON                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
INTESTINE LARGE,RECTUM                      | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
INTESTINE SMALL,DUODENUM                    | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  ADENOMA                                   |                                                                           |         1|
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        | X                                                                         |         1|
INTESTINE SMALL,JEJUNUM                     | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA,SINGLE             |             X     X              X                                        |         7|
  HEPATOCELLULAR ADENOMA,TWO                |                      X                                            X       |         2|
  HEPATOCELLULAR CARCINOMA,SINGLE           |                                                          X                |         2|
  HISTIOCYTIC SARCOMA                       |                                                                           |         2|
  LYMPHOMA MALIGNANT                        | X                                                                         |         1|
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        | X                                                                         |         1|
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
STOMACH                                     | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
STOMACH,FORESTOMACH                         | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
STOMACH,GLANDULAR                           | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +       | 45       |
ADRENAL GLAND,CORTEX                        | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +       | 45       |
ADRENAL GLAND,MEDULLA                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +       | 45       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   42
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:39.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 1| 1| 2| 2| 2| 2| 2| 2| 2| 6| 6| 7| 7| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2|         U      O|
CONTROL R 2YR 10    10                      | 8| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 4| 5| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
PITUITARY GLAND                             | A  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  M  +  +  +  +  +       | 43       |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
EPIDIDYMIS                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PREPUTIAL GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PROSTATE                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
SEMINAL VESICLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TESTES                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
LYMPH NODE                                  | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT,LUMBAR                 |                                                                           |         1|
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  M  M  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
  LYMPHOMA MALIGNANT                        | X                                                                         |         3|
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
  LYMPHOMA MALIGNANT                        | X              X  X                                                       |         6|
THYMUS                                      | M  +  +  M  +  +  +  +  M  +  +  +  +  M  +  +  +  +  +  +  +  +  +       | 39       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M       |  0       |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   43
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:39.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 1| 1| 2| 2| 2| 2| 2| 2| 2| 6| 6| 7| 7| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2|         U      O|
CONTROL R 2YR 10    10                      | 8| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 4| 5| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                X              X        X                                  |         9|
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                      X                          X                         |         2|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                X                                                          |         2|
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ADENOMA                                   |                               X                             X             |         4|
LACRIMAL GLAND                              | +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   44
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:39.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 1| 1| 2| 2| 2| 2| 2| 2| 2| 6| 6| 7| 7| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2|         U      O|
CONTROL R 2YR 10    10                      | 8| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 4| 5| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   45
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:40.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 1| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1|
                                            | 4| 4| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 6| 2| 2| 2| 2| 2| 2| 3| 3| 3| 5| 6| 7| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 6|   U      O|
25MG/KG R 2YR 11    11                      | 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 9| 0| 4| 5| 2| 3| 4| 5| 6| 7| 8| 9| 0| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +                                                                    + |          |
GALLBLADDER                                 | +  +                                                                    + |          |
INTESTINE LARGE                             | +  +                                                                    + |          |
INTESTINE LARGE,CECUM                       | +  +                                                                    + |          |
INTESTINE LARGE,COLON                       | +  +                                                                    + |          |
  HISTIOCYTIC SARCOMA                       |                                                                         X |          |
INTESTINE LARGE,RECTUM                      | +  +                                                                    + |          |
INTESTINE SMALL                             | +  +                                                           +        + |          |
INTESTINE SMALL,DUODENUM                    | +  +                                                                    + |          |
  HEMANGIOSARCOMA                           |                                                                           |          |
INTESTINE SMALL,ILEUM                       | +  +                                                                    + |          |
  HISTIOCYTIC SARCOMA                       |                                                                         X |          |
INTESTINE SMALL,JEJUNUM                     | +  +                                                           +        + |          |
  LYMPHOMA MALIGNANT                        |    X                                                           X          |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA,SINGLE             |             X  X  X  X                    X  X           X                |          |
  HEPATOCELLULAR CARCINOMA,SINGLE           |             X                                                             |          |
  HEPATOCELLULAR CARCINOMA,TWO              |                                                                           |          |
  HISTIOCYTIC SARCOMA                       |                                                                         X |          |
  LEUKEMIA GRANULOCYTIC                     |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
PANCREAS                                    | +  +                                                                    + |          |
SALIVARY GLANDS                             | +  +                                                                    + |          |
STOMACH                                     | +  +                                                                    + |          |
STOMACH,FORESTOMACH                         | +  +                                                                    + |          |
STOMACH,GLANDULAR                           | +  +                                                                    + |          |
TONGUE                                      | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +                                                                    + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
HEART                                       | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   46
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:40.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 1| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1|
                                            | 4| 4| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 6| 2| 2| 2| 2| 2| 2| 3| 3| 3| 5| 6| 7| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 6|   U      O|
25MG/KG R 2YR 11    11                      | 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 9| 0| 4| 5| 2| 3| 4| 5| 6| 7| 8| 9| 0| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +                                                                    + |          |
ADRENAL GLAND,CORTEX                        | +  +                                                                    + |          |
ADRENAL GLAND,MEDULLA                       | +  +                                                                    + |          |
ISLETS, PANCREATIC                          | +  +                                                                    + |          |
PARATHYROID GLAND                           | +  +                                                                    + |          |
PITUITARY GLAND                             | +  M                                                                    + |          |
  ADENOMA,PARS DISTALIS                     |                                                                           |          |
THYROID GLAND                               | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +                                                                    + |          |
EPIDIDYMIS                                  | +  +                                                                    + |          |
PREPUTIAL GLAND                             | +  +                                                                    + |          |
PROSTATE                                    | +  +                                                                    + |          |
  HISTIOCYTIC SARCOMA                       |                                                                         X |          |
SEMINAL VESICLE                             | +  +                                                                    + |          |
TESTES                                      | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +                                                                    + |          |
LYMPH NODE                                  | +  +                 +                                         +        + |          |
  HISTIOCYTIC SARCOMA,RENAL                 |                                                                         X |          |
  LYMPHOMA MALIGNANT,RENAL                  |                      X                                                    |          |
LYMPH NODE,MANDIBULAR                       | +  M                                                                    + |          |
LYMPH NODE,MESENTERIC                       | +  +                 +                                         +        + |          |
  HISTIOCYTIC SARCOMA                       |                                                                         X |          |
  LYMPHOMA MALIGNANT                        |    X                 X                                         X          |          |
SPLEEN                                      | +  +                                                           +        M |          |
  LEUKEMIA GRANULOCYTIC                     |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
THYMUS                                      | M  +                                                                    + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   47
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:41.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 1| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1|
                                            | 4| 4| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 6| 2| 2| 2| 2| 2| 2| 3| 3| 3| 5| 6| 7| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 6|   U      O|
25MG/KG R 2YR 11    11                      | 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 9| 0| 4| 5| 2| 3| 4| 5| 6| 7| 8| 9| 0| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M                                                                    M |          |
SKIN                                        | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +                                                                    + |          |
BONE,FEMUR                                  | +  +                                                                    + |          |
BONE,STERNUM                                | +  +                                                                    + |          |
SKELETAL MUSCLE                             | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +                                                                    + |          |
BRAIN,CEREBELLUM                            | +  +                                                                    + |          |
BRAIN,CEREBRUM                              | +  +                                                                    + |          |
PERIPHERAL NERVE                            | +  +                                                                    + |          |
SPINAL CORD                                 | M  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +                                                                    + |          |
LUNG                                        | +  +                                               +                    + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                    X                      |          |
  CARCINOMA,METASTATIC,HARDERIAN GLAND      |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
NOSE                                        | +  +                                                                    + |          |
TRACHEA                                     | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EAR                                         |                         +                                                 |          |
  FIBROUS HISTIOCYTOMA                      |                         X                                                 |          |
EYE                                         | +  +                                                                    + |          |
HARDERIAN GLAND                             | +  +                                   +                                + |          |
  ADENOMA                                   |                                        X                                  |          |
  CARCINOMA                                 |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   48
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:41.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 1| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1|
                                            | 4| 4| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 6| 2| 2| 2| 2| 2| 2| 3| 3| 3| 5| 6| 7| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 6|   U      O|
25MG/KG R 2YR 11    11                      | 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 9| 0| 4| 5| 2| 3| 4| 5| 6| 7| 8| 9| 0| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

LACRIMAL GLAND                              | +  +                                                                    + |          |
ZYMBAL'S GLAND                              | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +                                                                    + |          |
URINARY BLADDER                             | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   49
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:41.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 7| 2| 2| 2| 3| 3| 3| 3| 3| 3| 6| 6| 7| 7| 2| 2| 2| 3| 3| 3| 3| 3| 3|         U      O|
25MG/KG R 2YR 11    11                      | 2| 7| 8| 9| 0| 1| 2| 3| 4| 5| 2| 3| 6| 7| 7| 8| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +                                                                         |  4       |
GALLBLADDER                                 | +                                                                         |  4       |
INTESTINE LARGE                             | +                                                                         |  4       |
INTESTINE LARGE,CECUM                       | +                                                                         |  4       |
INTESTINE LARGE,COLON                       | +                                                                         |  4       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
INTESTINE LARGE,RECTUM                      | +                                                                         |  4       |
INTESTINE SMALL                             | +                                                                         |  5       |
INTESTINE SMALL,DUODENUM                    | +                                                                         |  4       |
  HEMANGIOSARCOMA                           | X                                                                         |         1|
INTESTINE SMALL,ILEUM                       | +                                                                         |  4       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
INTESTINE SMALL,JEJUNUM                     | +                                                                         |  5       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA,SINGLE             |                                                                           |         7|
  HEPATOCELLULAR CARCINOMA,SINGLE           |       X                    X                                              |         3|
  HEPATOCELLULAR CARCINOMA,TWO              |                                  X        X                               |         2|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LEUKEMIA GRANULOCYTIC                     |                                                          X                |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PANCREAS                                    | +                                                                         |  4       |
SALIVARY GLANDS                             | +                                                                         |  4       |
STOMACH                                     | +                                               +                         |  5       |
STOMACH,FORESTOMACH                         | +                                               +                         |  5       |
STOMACH,GLANDULAR                           | +                                               +                         |  5       |
TONGUE                                      | +                                                                         |  4       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +                                                                         |  4       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
HEART                                       | +                                                                         |  4       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   50
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:41.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 7| 2| 2| 2| 3| 3| 3| 3| 3| 3| 6| 6| 7| 7| 2| 2| 2| 3| 3| 3| 3| 3| 3|         U      O|
25MG/KG R 2YR 11    11                      | 2| 7| 8| 9| 0| 1| 2| 3| 4| 5| 2| 3| 6| 7| 7| 8| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +                                                                         |  4       |
ADRENAL GLAND,CORTEX                        | +                                                                         |  4       |
ADRENAL GLAND,MEDULLA                       | +                                                                         |  4       |
ISLETS, PANCREATIC                          | +                                                                         |  4       |
PARATHYROID GLAND                           | M                                                                         |  3       |
PITUITARY GLAND                             | M                                      +                                  |  3       |
  ADENOMA,PARS DISTALIS                     |                                        X                                  |         1|
THYROID GLAND                               | +                                                                         |  4       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +                                                                         |  4       |
EPIDIDYMIS                                  | +                                                                         |  4       |
PREPUTIAL GLAND                             | +                                                                         |  4       |
PROSTATE                                    | +                                                                         |  4       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
SEMINAL VESICLE                             | +                                                                         |  4       |
TESTES                                      | +                                                                         |  4       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +                                                                         |  4       |
LYMPH NODE                                  | +                                      +     +                            |  8       |
  HISTIOCYTIC SARCOMA,RENAL                 |                                                                           |         1|
  LYMPHOMA MALIGNANT,RENAL                  |                                                                           |         1|
LYMPH NODE,MANDIBULAR                       | +                                                                         |  3       |
LYMPH NODE,MESENTERIC                       | +                                      +     +                            |  8       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                              X                            |         4|
SPLEEN                                      | +     +                    +                 +           +                |  8       |
  LEUKEMIA GRANULOCYTIC                     |                                                          X                |         1|
  LYMPHOMA MALIGNANT                        |                                              X                            |         2|
THYMUS                                      | M                                                                         |  2       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   51
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:41.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 7| 2| 2| 2| 3| 3| 3| 3| 3| 3| 6| 6| 7| 7| 2| 2| 2| 3| 3| 3| 3| 3| 3|         U      O|
25MG/KG R 2YR 11    11                      | 2| 7| 8| 9| 0| 1| 2| 3| 4| 5| 2| 3| 6| 7| 7| 8| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M                                                                         |  0       |
SKIN                                        | +                                                                         |  4       |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +                                                                         |  4       |
BONE,FEMUR                                  | +                                                                         |  4       |
BONE,STERNUM                                | +                                                                         |  4       |
SKELETAL MUSCLE                             | +                                                                         |  4       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +                                                                         |  4       |
BRAIN,CEREBELLUM                            | +                                                                         |  4       |
BRAIN,CEREBRUM                              | +                                                                         |  4       |
PERIPHERAL NERVE                            | +                                                                         |  4       |
SPINAL CORD                                 | +                                                                         |  3       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +                                                                         |  4       |
LUNG                                        | +                                                  +                      |  6       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                                           |         1|
  CARCINOMA,METASTATIC,HARDERIAN GLAND      |                                                    X                      |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
NOSE                                        | +                                                                         |  4       |
TRACHEA                                     | +                                                                         |  4       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EAR                                         |                                                                           |  1       |
  FIBROUS HISTIOCYTOMA                      |                                                                           |         1|
EYE                                         | +                                                                         |  4       |
HARDERIAN GLAND                             | +                    +  +                          +                      |  8       |
  ADENOMA                                   |                      X  X                                                 |         3|
  CARCINOMA                                 |                                                    X                      |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   52
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:42.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 7| 2| 2| 2| 3| 3| 3| 3| 3| 3| 6| 6| 7| 7| 2| 2| 2| 3| 3| 3| 3| 3| 3|         U      O|
25MG/KG R 2YR 11    11                      | 2| 7| 8| 9| 0| 1| 2| 3| 4| 5| 2| 3| 6| 7| 7| 8| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

LACRIMAL GLAND                              | +                                                                         |  4       |
ZYMBAL'S GLAND                              | M                                                                         |  3       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +                                                                         |  4       |
URINARY BLADDER                             | +                                                                         |  4       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   53
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:42.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 4|   S      M|
                                            | 0| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|   U      O|
50 MG/KGR 2YR 12    12                      | 6| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 1| 2| 6| 7| 1| 2| 3| 4| 5| 6| 7| 8| 9| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +                                                                         |          |
GALLBLADDER                                 | +                                                                         |          |
INTESTINE LARGE                             | +                                                                         |          |
INTESTINE LARGE,CECUM                       | +                                                                         |          |
INTESTINE LARGE,COLON                       | +                                                                         |          |
INTESTINE LARGE,RECTUM                      | +                                                                         |          |
INTESTINE SMALL                             | +                                                                         |          |
INTESTINE SMALL,DUODENUM                    | +                                                                         |          |
INTESTINE SMALL,ILEUM                       | +                                                                         |          |
INTESTINE SMALL,JEJUNUM                     | +                                                                         |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA,SINGLE             |             X  X        X           X              X     X     X          |          |
  HEPATOCELLULAR CARCINOMA,SINGLE           |    X                                                                      |          |
  HEPATOCELLULAR CARCINOMA,TWO              |                                                                           |          |
PANCREAS                                    | +                                                                         |          |
SALIVARY GLANDS                             | +                                                                         |          |
STOMACH                                     | +                                                                         |          |
STOMACH,FORESTOMACH                         | +                                                                         |          |
STOMACH,GLANDULAR                           | +                                                                         |          |
TONGUE                                      | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +                                                                         |          |
HEART                                       | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +                                                                         |          |
ADRENAL GLAND,CORTEX                        | +                                                                         |          |
ADRENAL GLAND,MEDULLA                       | +                                                                         |          |
ISLETS, PANCREATIC                          | +                                                                         |          |
PARATHYROID GLAND                           | M                                                                         |          |
PITUITARY GLAND                             | +                                                                         |          |
THYROID GLAND                               | M                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   54
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:42.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 4|   S      M|
                                            | 0| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|   U      O|
50 MG/KGR 2YR 12    12                      | 6| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 1| 2| 6| 7| 1| 2| 3| 4| 5| 6| 7| 8| 9| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM

COAGULATING GLAND                           | +                                                                         |          |
EPIDIDYMIS                                  | +                                                                         |          |
PREPUTIAL GLAND                             | +                                                                         |          |
PROSTATE                                    | +                                                                         |          |
SEMINAL VESICLE                             | +                                                                         |          |
TESTES                                      | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +                                                                         |          |
LYMPH NODE                                  | +                                                                         |          |
LYMPH NODE,MANDIBULAR                       | +                                                                         |          |
LYMPH NODE,MESENTERIC                       | +                                                                         |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
SPLEEN                                      | +                                                                         |          |
  HEMANGIOSARCOMA                           |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
THYMUS                                      | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M                                                                         |          |
SKIN                                        | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +                                                                         |          |
BONE,FEMUR                                  | +                                                                         |          |
BONE,STERNUM                                | +                                                                         |          |
SKELETAL MUSCLE                             | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +                                                                         |          |
BRAIN,CEREBELLUM                            | +                                                                         |          |
BRAIN,CEREBRUM                              | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   55
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:42.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 4|   S      M|
                                            | 0| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|   U      O|
50 MG/KGR 2YR 12    12                      | 6| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 1| 2| 6| 7| 1| 2| 3| 4| 5| 6| 7| 8| 9| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM

PERIPHERAL NERVE                            | +                                                                         |          |
SPINAL CORD                                 | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +                                                                         |          |
LUNG                                        | +              +                                                          |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                X                                                          |          |
NOSE                                        | +                                                                         |          |
TRACHEA                                     | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +                                                                         |          |
HARDERIAN GLAND                             | +                                                                         |          |
  ADENOMA                                   |                                                                           |          |
LACRIMAL GLAND                              | +                                                                         |          |
ZYMBAL'S GLAND                              | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +                                                                         |          |
URINARY BLADDER                             | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   56
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:43.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 3| 3| 3| 4| 4| 4| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5|         U      O|
50 MG/KGR 2YR 12    12                      | 7| 8| 9| 0| 1| 2| 3| 4| 5| 4| 5| 8| 9| 6| 7| 8| 9| 0| 1| 2| 3| 4| 4|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   |                                                                           |  1       |
GALLBLADDER                                 |                                                                           |  1       |
INTESTINE LARGE                             |                                                                           |  1       |
INTESTINE LARGE,CECUM                       |                                                                           |  1       |
INTESTINE LARGE,COLON                       |                                                                           |  1       |
INTESTINE LARGE,RECTUM                      |                                                                           |  1       |
INTESTINE SMALL                             |                                                                           |  1       |
INTESTINE SMALL,DUODENUM                    |                                                                           |  1       |
INTESTINE SMALL,ILEUM                       |                                                                           |  1       |
INTESTINE SMALL,JEJUNUM                     |                                                                           |  1       |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA,SINGLE             |       X        X                                               X          |        10|
  HEPATOCELLULAR CARCINOMA,SINGLE           | X                       X                                                 |         3|
  HEPATOCELLULAR CARCINOMA,TWO              |                                              X                            |         1|
PANCREAS                                    |                                                                           |  1       |
SALIVARY GLANDS                             |                                                                           |  1       |
STOMACH                                     |                                                                           |  1       |
STOMACH,FORESTOMACH                         |                                                                           |  1       |
STOMACH,GLANDULAR                           |                                                                           |  1       |
TONGUE                                      |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                |                                                                           |  1       |
HEART                                       |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               |                                                                           |  1       |
ADRENAL GLAND,CORTEX                        |                                                                           |  1       |
ADRENAL GLAND,MEDULLA                       |                                                                           |  1       |
ISLETS, PANCREATIC                          |                                                                           |  1       |
PARATHYROID GLAND                           |                                                                           |  0       |
PITUITARY GLAND                             |                                                                           |  1       |
THYROID GLAND                               |                                                                           |  0       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   57
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:43.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 3| 3| 3| 4| 4| 4| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5|         U      O|
50 MG/KGR 2YR 12    12                      | 7| 8| 9| 0| 1| 2| 3| 4| 5| 4| 5| 8| 9| 6| 7| 8| 9| 0| 1| 2| 3| 4| 4|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM

COAGULATING GLAND                           |                                                                           |  1       |
EPIDIDYMIS                                  |                                                                           |  1       |
PREPUTIAL GLAND                             |                                                                           |  1       |
PROSTATE                                    |                                                                           |  1       |
SEMINAL VESICLE                             |                                                                           |  1       |
TESTES                                      |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 |                                                                           |  1       |
LYMPH NODE                                  | +                                         +                               |  3       |
LYMPH NODE,MANDIBULAR                       |                                                                           |  1       |
LYMPH NODE,MESENTERIC                       | +                                         +                               |  3       |
  LYMPHOMA MALIGNANT                        | X                                                                         |         1|
SPLEEN                                      | +  +                                         +                            |  4       |
  HEMANGIOSARCOMA                           |    X                                                                      |         1|
  LYMPHOMA MALIGNANT                        | X                                                                         |         1|
THYMUS                                      |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               |                                                                           |  0       |
SKIN                                        |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        |                                                                           |  1       |
BONE,FEMUR                                  |                                                                           |  1       |
BONE,STERNUM                                |                                                                           |  1       |
SKELETAL MUSCLE                             |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       |                                                                           |  1       |
BRAIN,CEREBELLUM                            |                                                                           |  1       |
BRAIN,CEREBRUM                              |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   58
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:43.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 3| 3| 3| 4| 4| 4| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5|         U      O|
50 MG/KGR 2YR 12    12                      | 7| 8| 9| 0| 1| 2| 3| 4| 5| 4| 5| 8| 9| 6| 7| 8| 9| 0| 1| 2| 3| 4| 4|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM

PERIPHERAL NERVE                            |                                                                           |  1       |
SPINAL CORD                                 |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      |                                                                           |  1       |
LUNG                                        |                               +                 +              +          |  5       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                               X                                X          |         3|
NOSE                                        |                                                                           |  1       |
TRACHEA                                     |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         |                                                                           |  1       |
HARDERIAN GLAND                             |                                              +                            |  2       |
  ADENOMA                                   |                                              X                            |         1|
LACRIMAL GLAND                              |                                                                           |  1       |
ZYMBAL'S GLAND                              |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      |                                                                           |  1       |
URINARY BLADDER                             |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   59
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:50.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 4| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 1| 8| 2| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
                                            | 1| 5| 8| 4| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 2| 6| 7| 4| 4| 4| 4| 4| 4| 4| 5| 6| 6| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| 6|   U      O|
100MG/KGR 2YR 13    13                      | 4| 1| 1| 7| 3| 4| 5| 6| 7| 8| 9| 0| 3| 4| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 1|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
GALLBLADDER                                 | +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,CECUM                       | +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE LARGE,COLON                       | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE LARGE,RECTUM                      | +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL                             | +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE SMALL,DUODENUM                    | +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE SMALL,ILEUM                       | +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE SMALL,JEJUNUM                     | +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |       X                                                                   |          |
  HEPATOCELLULAR ADENOMA,SINGLE             |                                  X                                X     X |          |
  HEPATOCELLULAR ADENOMA,TWO                |                                                 X                         |          |
  HEPATOCELLULAR CARCINOMA,FOUR             |                                                                           |          |
  HEPATOCELLULAR CARCINOMA,SINGLE           |    X     X     X                                                          |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
STOMACH                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   60
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:50.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 4| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 1| 8| 2| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
                                            | 1| 5| 8| 4| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 2| 6| 7| 4| 4| 4| 4| 4| 4| 4| 5| 6| 6| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| 6|   U      O|
100MG/KGR 2YR 13    13                      | 4| 1| 1| 7| 3| 4| 5| 6| 7| 8| 9| 0| 3| 4| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 1|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  + |          |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  + |          |
PITUITARY GLAND                             | M  +  M  +  +  +  M  +  M  +  +  +  +  +  +  +  M  +  +  +  +  M  M  +  M |          |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
EPIDIDYMIS                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROMA                                   |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
PREPUTIAL GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PROSTATE                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  M  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
SEMINAL VESICLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TESTES                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT,AXILLARY               |                                                                           |          |
  LYMPHOMA MALIGNANT,INGUINAL               |                                                                           |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |                                                                           |          |
  LYMPHOMA MALIGNANT,POPLITEAL              |                                                                           |          |
  LYMPHOMA MALIGNANT,RENAL                  |                                                                           |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                   X                                         X             |          |
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   61
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:50.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 4| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 1| 8| 2| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
                                            | 1| 5| 8| 4| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 2| 6| 7| 4| 4| 4| 4| 4| 4| 4| 5| 6| 6| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| 6|   U      O|
100MG/KGR 2YR 13    13                      | 4| 1| 1| 7| 3| 4| 5| 6| 7| 8| 9| 0| 3| 4| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 1|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  HEMANGIOSARCOMA                           |       X                                                                   |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                   X                                                       |          |
THYMUS                                      | +  M  A  M  +  +  M  +  +  +  +  M  M  +  M  +  M  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M |          |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBRUM                              | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                 X        X  X             |          |
  CARCINOMA,METASTATIC,HARDERIAN GLAND      |                                                                           |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |          X                                                                |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   62
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:50.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 4| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 1| 8| 2| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
                                            | 1| 5| 8| 4| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 2| 6| 7| 4| 4| 4| 4| 4| 4| 4| 5| 6| 6| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| 6|   U      O|
100MG/KGR 2YR 13    13                      | 4| 1| 1| 7| 3| 4| 5| 6| 7| 8| 9| 0| 3| 4| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 1|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                                              X        X                   |          |
  CARCINOMA                                 |                                                                           |          |
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  M  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
ZYMBAL'S GLAND                              | +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   63
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:57.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 2| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 7| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 8| 8| 4| 4| 4| 4| 4| 5| 5| 5| 5|         U      O|
100MG/KGR 2YR 13    13                      | 8| 6| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 0| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
GALLBLADDER                                 | A  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  M  +  +       | 43       |
INTESTINE LARGE                             | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
INTESTINE LARGE,CECUM                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
INTESTINE LARGE,COLON                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
INTESTINE LARGE,RECTUM                      | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE SMALL                             | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
INTESTINE SMALL,DUODENUM                    | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
INTESTINE SMALL,ILEUM                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
INTESTINE SMALL,JEJUNUM                     | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA                           |                                                          X                |         2|
  HEPATOCELLULAR ADENOMA,SINGLE             |             X           X     X  X                 X           X          |         9|
  HEPATOCELLULAR ADENOMA,TWO                |                                                                           |         1|
  HEPATOCELLULAR CARCINOMA,FOUR             |                                                             X             |         1|
  HEPATOCELLULAR CARCINOMA,SINGLE           | X                                      X        X        X                |         7|
  HISTIOCYTIC SARCOMA                       |    X                                      X                               |         2|
  LYMPHOMA MALIGNANT                        |                      X                 X                                  |         2|
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
STOMACH                                     | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
STOMACH,FORESTOMACH                         | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
STOMACH,GLANDULAR                           | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA                       |    X                                                                      |         1|
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA                       |    X                                                                      |         1|
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   64
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:57.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 2| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 7| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 8| 8| 4| 4| 4| 4| 4| 5| 5| 5| 5|         U      O|
100MG/KGR 2YR 13    13                      | 8| 6| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 0| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
PITUITARY GLAND                             | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +       | 38       |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
EPIDIDYMIS                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  FIBROMA                                   |                                                                   X       |         1|
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
PREPUTIAL GLAND                             | +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
PROSTATE                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
SEMINAL VESICLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TESTES                                      | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT,AXILLARY               |                                        X                                  |         1|
  LYMPHOMA MALIGNANT,INGUINAL               |                                        X                                  |         1|
  LYMPHOMA MALIGNANT,LUMBAR                 |                                        X                                  |         1|
  LYMPHOMA MALIGNANT,POPLITEAL              |                                        X                                  |         1|
  LYMPHOMA MALIGNANT,RENAL                  |                                        X                                  |         1|
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA                       |    X  X                                   X                               |         3|
  LYMPHOMA MALIGNANT                        |                                        X                                  |         3|
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   65
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:57.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 2| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 7| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 8| 8| 4| 4| 4| 4| 4| 5| 5| 5| 5|         U      O|
100MG/KGR 2YR 13    13                      | 8| 6| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 0| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  HEMANGIOSARCOMA                           |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |    X                                      X                               |         2|
  LYMPHOMA MALIGNANT                        |                                        X                                  |         2|
THYMUS                                      | +  M  M  +  M  +  +  M  +  M  M  M  M  +  +  +  M  +  +  +  +  M  +       | 30       |
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M  M  M  M  M  M  M  M  +  M  M  M  M  M  M  M  M  M  M  M       |  2       |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +       | 47       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                        X                          X       |         5|
  CARCINOMA,METASTATIC,HARDERIAN GLAND      |             X                                                             |         1|
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |    X                                                                      |         1|
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   66
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:57.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 2| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 7| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 8| 8| 4| 4| 4| 4| 4| 5| 5| 5| 5|         U      O|
100MG/KGR 2YR 13    13                      | 8| 6| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 0| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ADENOMA                                   | X                             X                                           |         4|
  CARCINOMA                                 |             X                                                             |         1|
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   67
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:58.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 3| 3| 3| 5| 5| 5| 3| 3| 3| 5| 5| 5|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3|                                          S      M|
                                            | 2| 2| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4|                                          U      O|
CONTROL R 64W 14    14                      | 2| 3| 4| 6| 7| 8| 3| 4| 5| 7| 8| 9|                                          E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +                                        | 12       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   68
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:58.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 3| 3| 3| 5| 5| 5| 3| 3| 3| 5| 5| 5|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3|                                          S      M|
                                            | 2| 2| 2| 4| 5| 5| 2| 2| 2| 5| 5| 5|                                          U      O|
25 MG/KGR 64W 15    15                      | 5| 6| 7| 9| 0| 1| 6| 7| 8| 0| 1| 2|                                          E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +                                        | 12       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   69
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:58.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 3| 3| 3| 5| 5| 5| 3| 3| 3| 5| 5| 5|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3|                                          S      M|
                                            | 2| 2| 3| 5| 5| 5| 2| 3| 3| 5| 5| 5|                                          U      O|
50 MG/KGR 64W 16    16                      | 8| 9| 0| 2| 3| 4| 9| 0| 1| 3| 4| 5|                                          E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +                                        | 12       |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

SKIN                                        |                                  +                                        |  1       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   70
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:58.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 3| 3| 3| 5| 5| 5| 3| 3| 3| 5| 5| 5|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3|                                          S      M|
                                            | 3| 3| 3| 5| 5| 5| 3| 3| 3| 5| 5| 5|                                          U      O|
100MG/KGR 64W 17    17                      | 1| 2| 3| 5| 6| 7| 2| 3| 4| 6| 7| 8|                                          E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +                                        | 12       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED