Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
https://ntp.niehs.nih.gov/go/11431

NCTR Study 211701 Pathology Tables

NCTR EXP/TEST:   211701                                                                                      PAGE:    1
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:47.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 1| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 8|
                                            | 0| 3| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 8|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3|   S      M|
                                            | 5| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 5| 5| 6| 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 6|   U      O|
CONTROL A 2YR  1     1                      | 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| 8| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
GALLBLADDER                                 | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
INTESTINE LARGE                             | A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE LARGE,CECUM                       | A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE LARGE,COLON                       | A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE LARGE,RECTUM                      | A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE SMALL                             | A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE SMALL,DUODENUM                    | A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
  LYMPHOMA MALIGNANT                        |       X                          X                                        |          |
INTESTINE SMALL,ILEUM                       | A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
  LYMPHOMA MALIGNANT                        |                                  X                                        |          |
INTESTINE SMALL,JEJUNUM                     | A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
  LYMPHOMA MALIGNANT                        |                                  X                                        |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA,SINGLE             | X     X                                                  X        X  X    |          |
  HEPATOCELLULAR ADENOMA,TWO                |                                           X                               |          |
  HEPATOCELLULAR CARCINOMA,FOUR             |                                                                         X |          |
  HEPATOCELLULAR CARCINOMA,SINGLE           |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
PANCREAS                                    | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
STOMACH                                     | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
STOMACH,FORESTOMACH                         | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
STOMACH,GLANDULAR                           | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:    2
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:47.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 1| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 8|
                                            | 0| 3| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 8|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3|   S      M|
                                            | 5| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 5| 5| 6| 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 6|   U      O|
CONTROL A 2YR  1     1                      | 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| 8| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  M |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  M |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  M |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  CARCINOMA                                 |                                                                           |          |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
PITUITARY GLAND                             | +  M  M  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA,FOLLICULAR CELL                   |                                                                           |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
EPIDIDYMIS                                  | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
PREPUTIAL GLAND                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
PROSTATE                                    | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
SEMINAL VESICLE                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
TESTES                                      | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA,INTERSTITIAL CELL                 |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA,METASTATIC,SPLEEN         |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT,AXILLARY               |    X                                                                      |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |    X                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:    3
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:47.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 1| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 8|
                                            | 0| 3| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 8|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3|   S      M|
                                            | 5| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 5| 5| 6| 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 6|   U      O|
CONTROL A 2YR  1     1                      | 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| 8| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  LYMPHOMA MALIGNANT,RENAL                  |    X                                                                      |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA,METASTATIC,SPLEEN         |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X  X                                            X                      |          |
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X  X                          X                 X                      |          |
THYMUS                                      | +  +  +  +  +  +  M  +  +  +  M  +  +  M  M  +  +  +  M  M  +  +  M  M  M |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  M  M  M  M  M  +  +  M  +  M  M  M  M  M  M  M  M  M  M  M  M  M  M |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROMA                                   |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:    4
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:47.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 1| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 8|
                                            | 0| 3| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 8|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3|   S      M|
                                            | 5| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 5| 5| 6| 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 6|   U      O|
CONTROL A 2YR  1     1                      | 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| 8| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |          X           X     X                    X     X        X          |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA,TWO          |                                                                           |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                  X     X                                  |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                         X |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ZYMBAL'S GLAND                              | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
URINARY BLADDER                             | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:    5
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:55.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 0| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 8| 7| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|         S      M|
                                            | 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 5| 6| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9|         U      O|
CONTROL A 2YR  1     1                      | 0| 1| 9| 1| 2| 3| 4| 5| 6| 7| 8| 5| 8| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
GALLBLADDER                                 | A  A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
INTESTINE LARGE                             | A  A  A  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +       | 41       |
INTESTINE LARGE,CECUM                       | A  A  A  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +       | 41       |
INTESTINE LARGE,COLON                       | A  A  A  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +       | 41       |
INTESTINE LARGE,RECTUM                      | A  A  A  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +       | 41       |
INTESTINE SMALL                             | A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 42       |
INTESTINE SMALL,DUODENUM                    | A  A  A  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +       | 41       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
INTESTINE SMALL,ILEUM                       | A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 42       |
  LYMPHOMA MALIGNANT                        |                                     X                                     |         2|
INTESTINE SMALL,JEJUNUM                     | A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 42       |
  LYMPHOMA MALIGNANT                        |                                     X                                     |         2|
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA,SINGLE             | X  X                 X        X                             X             |        10|
  HEPATOCELLULAR ADENOMA,TWO                |                   X                                                       |         2|
  HEPATOCELLULAR CARCINOMA,FOUR             |                                                                           |         1|
  HEPATOCELLULAR CARCINOMA,SINGLE           |       X                                                        X  X       |         3|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
PANCREAS                                    | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
STOMACH                                     | A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
STOMACH,FORESTOMACH                         | A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
STOMACH,GLANDULAR                           | A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
TONGUE                                      | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:    6
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:55.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 0| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 8| 7| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|         S      M|
                                            | 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 5| 6| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9|         U      O|
CONTROL A 2YR  1     1                      | 0| 1| 9| 1| 2| 3| 4| 5| 6| 7| 8| 5| 8| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
ADRENAL GLAND,CORTEX                        | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
  LYMPHOMA MALIGNANT                        |                                     X                                     |         2|
ADRENAL GLAND,MEDULLA                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  CARCINOMA                                 |                X                                                          |         1|
PARATHYROID GLAND                           | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PITUITARY GLAND                             | +  A  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  M  +  +  +  +       | 42       |
THYROID GLAND                               | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  ADENOMA,FOLLICULAR CELL                   |          X                                                                |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
EPIDIDYMIS                                  | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PREPUTIAL GLAND                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PROSTATE                                    | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SEMINAL VESICLE                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
TESTES                                      | A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
  ADENOMA,INTERSTITIAL CELL                 |                                                                   X       |         1|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  HEMANGIOSARCOMA,METASTATIC,SPLEEN         | X                                                                         |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT,AXILLARY               |                                                                           |         1|
  LYMPHOMA MALIGNANT,LUMBAR                 |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:    7
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:55.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 0| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 8| 7| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|         S      M|
                                            | 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 5| 6| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9|         U      O|
CONTROL A 2YR  1     1                      | 0| 1| 9| 1| 2| 3| 4| 5| 6| 7| 8| 5| 8| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  LYMPHOMA MALIGNANT,RENAL                  |                                     X                                     |         2|
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
LYMPH NODE,MESENTERIC                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  HEMANGIOSARCOMA,METASTATIC,SPLEEN         | X                                                                         |         1|
  LYMPHOMA MALIGNANT                        |                                     X                                     |         4|
SPLEEN                                      | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  HEMANGIOSARCOMA                           | X                                                                         |         1|
  LYMPHOMA MALIGNANT                        |                                     X                                     |         5|
THYMUS                                      | +  M  M  +  +  +  +  M  +  +  +  +  M  +  +  M  +  M  M  M  M  M  +       | 29       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M       |  5       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  FIBROMA                                   |                                                                X          |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
BONE,FEMUR                                  | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
BONE,STERNUM                                | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SKELETAL MUSCLE                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
BRAIN,CEREBELLUM                            | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
BRAIN,CEREBRUM                              | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
PERIPHERAL NERVE                            | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
SPINAL CORD                                 | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:    8
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:55.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 0| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 8| 7| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|         S      M|
                                            | 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 5| 6| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9|         U      O|
CONTROL A 2YR  1     1                      | 0| 1| 9| 1| 2| 3| 4| 5| 6| 7| 8| 5| 8| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

LARYNX                                      | +  A  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |          X              X     X           X  X           X                |        12|
  ALVEOLAR/BRONCHIOLAR ADENOMA,TWO          |    X                                                                      |         1|
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                                                           |         2|
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
NOSE                                        | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
TRACHEA                                     | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
HARDERIAN GLAND                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  ADENOMA                                   |                X                 X        X                 X  X          |         5|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M       | 47       |
ZYMBAL'S GLAND                              | +  A  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
URINARY BLADDER                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:    9
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:58.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 3| 5| 7| 3| 2| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 3| 6| 5| 4| 8| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 5|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3|   S      M|
                                            | 6| 6| 6| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| 5| 6| 6| 8| 9| 9| 9| 9| 9| 9| 6|   U      O|
25 MG/KGA 2YR  2     2                      | 4| 6| 8| 4| 5| 6| 1| 2| 3| 4| 5| 6| 7| 8| 3| 7| 8| 9| 0| 1| 2| 3| 4| 5| 4|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +                                                        + |          |
GALLBLADDER                                 | +  +  +  +  +  +                                                        + |          |
INTESTINE LARGE                             | +  +  A  A  A  A                                                        A |          |
INTESTINE LARGE,CECUM                       | +  +  A  A  A  A                                                        A |          |
INTESTINE LARGE,COLON                       | +  +  A  A  A  A                                                        A |          |
INTESTINE LARGE,RECTUM                      | +  +  A  A  A  A                                                        A |          |
INTESTINE SMALL                             | +  +  A  A  +  A           +                                            A |          |
INTESTINE SMALL,DUODENUM                    | +  +  A  A  +  A           +                                            A |          |
  LYMPHOMA MALIGNANT                        |                            X                                              |          |
INTESTINE SMALL,ILEUM                       | +  +  A  A  A  A                                                        A |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
INTESTINE SMALL,JEJUNUM                     | +  +  A  A  A  A                                                        A |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOMA                                |                                              X                            |          |
  HEPATOCELLULAR ADENOMA,FOUR               |                                                                      X    |          |
  HEPATOCELLULAR ADENOMA,MULTIPLE           |             X                                                             |          |
  HEPATOCELLULAR ADENOMA,SINGLE             | X              X     X     X              X        X     X  X             |          |
  HEPATOCELLULAR ADENOMA,THREE              |                                                                           |          |
  HEPATOCELLULAR ADENOMA,TWO                |          X        X                          X                            |          |
  HEPATOCELLULAR CARCINOMA                  |       X                                                                   |          |
  HEPATOCELLULAR CARCINOMA,SINGLE           |                X  X              X                       X              X |          |
PANCREAS                                    | +  +  +  +  +  +                                                        + |          |
  CARCINOMA,DUCT                            |       X                                                                   |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
SALIVARY GLANDS                             | +  +  A  +  +  +                                                        + |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
STOMACH                                     | +  +  +  +  +  +                                                        + |          |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +                                                        + |          |
STOMACH,GLANDULAR                           | +  +  +  +  +  +                                                        + |          |
TONGUE                                      | +  +  +  +  +  +                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +                                                        + |          |
  CARCINOMA,METASTATIC,PANCREAS             |       X                                                                   |          |
HEART                                       | +  +  +  +  +  +                                                        + |          |
  CARCINOMA,METASTATIC,PANCREAS             |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   10
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:58.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 3| 5| 7| 3| 2| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 3| 6| 5| 4| 8| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 5|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3|   S      M|
                                            | 6| 6| 6| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| 5| 6| 6| 8| 9| 9| 9| 9| 9| 9| 6|   U      O|
25 MG/KGA 2YR  2     2                      | 4| 6| 8| 4| 5| 6| 1| 2| 3| 4| 5| 6| 7| 8| 3| 7| 8| 9| 0| 1| 2| 3| 4| 5| 4|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +                                                        + |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +                                                        + |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +                                                        + |          |
ISLETS, PANCREATIC                          | +  +  +  +  +  +                                                        + |          |
PARATHYROID GLAND                           | +  +  M  M  +  M                                                        + |          |
PITUITARY GLAND                             | M  +  +  +  +  +                                                        + |          |
THYROID GLAND                               | +  +  +  +  +  +                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +  +  +                                                        + |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
EPIDIDYMIS                                  | +  +  +  +  +  +                                                        + |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
PREPUTIAL GLAND                             | +  +  M  +  +  +                                                        + |          |
PROSTATE                                    | +  +  +  +  +  +                                                        + |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
SEMINAL VESICLE                             | +  +  +  +  +  +                                                        + |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
TESTES                                      | +  +  +  +  +  +                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +                                                        + |          |
LYMPH NODE                                  | +  +  +  +  +  +  +        +  +                    +                    + |          |
  HISTIOCYTIC SARCOMA,BRONCHIAL             |                                                                           |          |
  HISTIOCYTIC SARCOMA,RENAL                 |                                                                           |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |                               X                                           |          |
LYMPH NODE,MANDIBULAR                       | +  +  A  +  +  +                                                        + |          |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +           +  +                    +                    + |          |
  CARCINOMA,METASTATIC,PANCREAS             |       X                                                                   |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                            X  X                                           |          |
SPLEEN                                      | +  +  +  +  +  +  +        +  +           +        +     +              + |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                            X  X                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   11
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:58.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 3| 5| 7| 3| 2| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 3| 6| 5| 4| 8| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 5|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3|   S      M|
                                            | 6| 6| 6| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| 5| 6| 6| 8| 9| 9| 9| 9| 9| 9| 6|   U      O|
25 MG/KGA 2YR  2     2                      | 4| 6| 8| 4| 5| 6| 1| 2| 3| 4| 5| 6| 7| 8| 3| 7| 8| 9| 0| 1| 2| 3| 4| 5| 4|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

THYMUS                                      | +  M  M  +  +  M           +                                            M |          |
  LYMPHOMA MALIGNANT                        |                            X                                              |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M  M  M                                                        M |          |
SKIN                                        | +  +  +  +  +  +                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +                                                        + |          |
BONE,FEMUR                                  | +  +  +  +  +  +                                                        + |          |
BONE,STERNUM                                | +  +  +  +  +  +                                                        + |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +                                                        + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +                                                        + |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +                                                        + |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +                                                        + |          |
SPINAL CORD                                 | +  +  +  +  +  +                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +                                                        + |          |
LUNG                                        | +  +  +  +  +  +  +     +                                   +           + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |          X                                                  X             |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA,TWO          |                         X                                                 |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            | X  X                    X                                                 |          |
  CARCINOMA,METASTATIC,PANCREAS             |       X                                                                   |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
NOSE                                        | +  +  +  +  +  +                                                        + |          |
TRACHEA                                     | +  +  +  +  +  +                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   12
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:23:58.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 3| 5| 7| 3| 2| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 3| 6| 5| 4| 8| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 5|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3|   S      M|
                                            | 6| 6| 6| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| 5| 6| 6| 8| 9| 9| 9| 9| 9| 9| 6|   U      O|
25 MG/KGA 2YR  2     2                      | 4| 6| 8| 4| 5| 6| 1| 2| 3| 4| 5| 6| 7| 8| 3| 7| 8| 9| 0| 1| 2| 3| 4| 5| 4|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +                          +                             + |          |
HARDERIAN GLAND                             | +  +  +  +  +  +     +  +                 +           +                 + |          |
  ADENOMA                                   |                      X                    X           X                 X |          |
  CARCINOMA                                 |                         X                                                 |          |
LACRIMAL GLAND                              | +  +  A  +  +  +                                                        + |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
ZYMBAL'S GLAND                              | +  +  +  +  +  M                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +                                                        + |          |
  CARCINOMA,METASTATIC,PANCREAS             |       X                                                                   |          |
URINARY BLADDER                             | +  +  +  +  +  +                                                        + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   13
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:00.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 2| 1| 2| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 4| 7| 2| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|         S      M|
                                            | 6| 7| 7| 7| 8| 9| 9| 9| 9| 9| 9| 9| 9| 5| 5| 6| 9| 9| 9| 9| 9| 9| 9|         U      O|
25 MG/KGA 2YR  2     2                      | 9| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 7| 6| 7| 9| 2| 3| 4| 5| 6| 7| 8|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +                                                                | 11       |
GALLBLADDER                                 | +  +  +  M                                                                | 10       |
INTESTINE LARGE                             | +  +  +  A                                                                |  5       |
INTESTINE LARGE,CECUM                       | +  +  +  A                                                                |  5       |
INTESTINE LARGE,COLON                       | +  +  +  A                                                                |  5       |
INTESTINE LARGE,RECTUM                      | +  +  +  A                                                                |  5       |
INTESTINE SMALL                             | +  +  +  A                                                                |  7       |
INTESTINE SMALL,DUODENUM                    | +  +  +  A                                                                |  7       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
INTESTINE SMALL,ILEUM                       | +  +  +  A                                                                |  5       |
  HISTIOCYTIC SARCOMA                       |    X                                                                      |         1|
INTESTINE SMALL,JEJUNUM                     | +  +  +  A                                                                |  5       |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOMA                                |                                                                           |         1|
  HEPATOCELLULAR ADENOMA,FOUR               |                                                                           |         1|
  HEPATOCELLULAR ADENOMA,MULTIPLE           |                                                                           |         1|
  HEPATOCELLULAR ADENOMA,SINGLE             |                X        X  X                                              |        11|
  HEPATOCELLULAR ADENOMA,THREE              |       X                                                                   |         1|
  HEPATOCELLULAR ADENOMA,TWO                |             X                          X                                  |         5|
  HEPATOCELLULAR CARCINOMA                  |                                                                           |         1|
  HEPATOCELLULAR CARCINOMA,SINGLE           | X        X                 X                                X             |         9|
PANCREAS                                    | +  +  +  M                                                                | 10       |
  CARCINOMA,DUCT                            |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |    X                                                                      |         1|
SALIVARY GLANDS                             | +  +  +  +                                                                | 10       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
STOMACH                                     | +  +  +  A                                                                | 10       |
STOMACH,FORESTOMACH                         | +  +  +  A                                                                | 10       |
STOMACH,GLANDULAR                           | +  +  +  A                                                                | 10       |
TONGUE                                      | +  +  +  A                                                                | 10       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +                                                                | 11       |
  CARCINOMA,METASTATIC,PANCREAS             |                                                                           |         1|
HEART                                       | +  +  +  +                                                                | 11       |
  CARCINOMA,METASTATIC,PANCREAS             |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   14
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:00.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 2| 1| 2| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 4| 7| 2| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|         S      M|
                                            | 6| 7| 7| 7| 8| 9| 9| 9| 9| 9| 9| 9| 9| 5| 5| 6| 9| 9| 9| 9| 9| 9| 9|         U      O|
25 MG/KGA 2YR  2     2                      | 9| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 7| 6| 7| 9| 2| 3| 4| 5| 6| 7| 8|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +                                                                | 11       |
ADRENAL GLAND,CORTEX                        | +  +  +  +                                                                | 11       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
ADRENAL GLAND,MEDULLA                       | +  +  +  +                                                                | 11       |
ISLETS, PANCREATIC                          | +  +  +  M                                                                | 10       |
PARATHYROID GLAND                           | +  +  M  M                                                                |  6       |
PITUITARY GLAND                             | +  +  +  +                                                                | 10       |
THYROID GLAND                               | +  +  +  +                                                                | 11       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  A                                                                | 10       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
EPIDIDYMIS                                  | +  +  +  A                                                                | 10       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PREPUTIAL GLAND                             | +  +  +  A     +                                                          | 10       |
PROSTATE                                    | +  +  +  A                                                                | 10       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SEMINAL VESICLE                             | +  +  +  A                                         +                      | 11       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
TESTES                                      | +  +  +  +                                                                | 11       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  A                                                                | 10       |
LYMPH NODE                                  | +  +  +  +                                                                | 15       |
  HISTIOCYTIC SARCOMA,BRONCHIAL             |    X                                                                      |         1|
  HISTIOCYTIC SARCOMA,RENAL                 |       X                                                                   |         1|
  LYMPHOMA MALIGNANT,LUMBAR                 |                                                                           |         1|
LYMPH NODE,MANDIBULAR                       | +  +  +  +                                                                | 10       |
LYMPH NODE,MESENTERIC                       | +  +  +  A                                                                | 13       |
  CARCINOMA,METASTATIC,PANCREAS             |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |    X  X                                                                   |         2|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
SPLEEN                                      | +  +  +  A                                                                | 16       |
  HISTIOCYTIC SARCOMA                       |       X                                                                   |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   15
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:00.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 2| 1| 2| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 4| 7| 2| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|         S      M|
                                            | 6| 7| 7| 7| 8| 9| 9| 9| 9| 9| 9| 9| 9| 5| 5| 6| 9| 9| 9| 9| 9| 9| 9|         U      O|
25 MG/KGA 2YR  2     2                      | 9| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 7| 6| 7| 9| 2| 3| 4| 5| 6| 7| 8|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

THYMUS                                      | M  M  +  M                                                     +          |  6       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M                                                                |  0       |
SKIN                                        | +  +  +  A                                                                | 10       |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +                                                                | 11       |
BONE,FEMUR                                  | +  +  +  +                                                                | 11       |
BONE,STERNUM                                | +  +  +  +                                                                | 11       |
SKELETAL MUSCLE                             | +  +  +  A                                                                | 10       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  A                                                                | 10       |
BRAIN,CEREBELLUM                            | +  +  +  A                                                                | 10       |
BRAIN,CEREBRUM                              | +  +  +  A                                                                | 10       |
PERIPHERAL NERVE                            | +  +  +  A                                                                | 10       |
SPINAL CORD                                 | +  +  +  A                                                                | 10       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +                                                                | 11       |
LUNG                                        | +  +  +  +  +              +        +                 +        +  +       | 20       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                            X                          X        X  X       |         6|
  ALVEOLAR/BRONCHIOLAR ADENOMA,TWO          |             X                                                             |         2|
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                     X                                     |         4|
  CARCINOMA,METASTATIC,PANCREAS             |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
NOSE                                        | +  +  +  +                                                                | 11       |
TRACHEA                                     | +  +  +  A                                                                | 10       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   16
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:00.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 2| 1| 2| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 4| 7| 2| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|         S      M|
                                            | 6| 7| 7| 7| 8| 9| 9| 9| 9| 9| 9| 9| 9| 5| 5| 6| 9| 9| 9| 9| 9| 9| 9|         U      O|
25 MG/KGA 2YR  2     2                      | 9| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 7| 6| 7| 9| 2| 3| 4| 5| 6| 7| 8|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  A                                                                | 11       |
HARDERIAN GLAND                             | +  +  +  A           +                    +                               | 16       |
  ADENOMA                                   |                      X                    X                               |         6|
  CARCINOMA                                 |                                                                           |         1|
LACRIMAL GLAND                              | +  +  +  +                                                                | 10       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
ZYMBAL'S GLAND                              | +  +  +  A                                                                |  9       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  A                                                                | 10       |
  CARCINOMA,METASTATIC,PANCREAS             |                                                                           |         1|
URINARY BLADDER                             | +  +  +  A                                                                | 10       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   17
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:04.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 5| 5| 8| 2| 2| 4| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 2| 2| 1| 8| 9| 7| 5| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 6| 6| 7| 7| 7| 8| 9| 0| 0| 0| 0| 0| 0| 5| 6| 9| 9| 9| 9| 0| 0| 0| 0| 6|   U      O|
50 MG/KGA 2YR  3     3                      | 5| 5| 9| 2| 3| 8| 1| 9| 0| 1| 2| 3| 4| 5| 4| 9| 6| 7| 8| 9| 0| 1| 2| 3| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +                                                     + |          |
GALLBLADDER                                 | +  +  +  +  +  +  +                                                     + |          |
INTESTINE LARGE                             | +  A  A  A  A  A  +                                                     A |          |
INTESTINE LARGE,CECUM                       | +  A  A  A  A  A  +                                                     A |          |
INTESTINE LARGE,COLON                       | +  A  A  A  A  A  +                                                     A |          |
INTESTINE LARGE,RECTUM                      | +  A  A  A  A  A  +                                                     A |          |
INTESTINE SMALL                             | +  A  A  A  A  A  +        +                                            A |          |
INTESTINE SMALL,DUODENUM                    | +  A  A  A  A  A  +                                                     A |          |
INTESTINE SMALL,ILEUM                       | +  A  A  A  A  A  +        +                                            A |          |
  LYMPHOMA MALIGNANT                        |                            X                                              |          |
INTESTINE SMALL,JEJUNUM                     | +  A  A  A  A  A  +                                                     A |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  CARCINOMA,BILE DUCT                       |                X                                                          |          |
  HEPATOCELLULAR ADENOMA,MULTIPLE           |                                  X                                        |          |
  HEPATOCELLULAR ADENOMA,SINGLE             |                               X                                         X |          |
  HEPATOCELLULAR ADENOMA,THREE              |                                                    X                 X    |          |
  HEPATOCELLULAR ADENOMA,TWO                |                      X                                                    |          |
  HEPATOCELLULAR CARCINOMA,SINGLE           |                X                                                        X |          |
  HEPATOCELLULAR CARCINOMA,THREE            |          X                                                           X    |          |
  HEPATOCELLULAR CARCINOMA,TWO              |             X                                                             |          |
  LYMPHOMA MALIGNANT                        |    X                                   X                                  |          |
MESENTERY                                   |       +                                                                   |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
PANCREAS                                    | +  +  M  +  +  +  +                                                     + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
  NEOPLASM NOS                              |                X                                                          |          |
SALIVARY GLANDS                             | +  +  +  A  +  +  +                                                     + |          |
STOMACH                                     | +  +  +  +  +  +  +                                                     + |          |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +                                                     + |          |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +                                                     + |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
TONGUE                                      | +  +  +  +  +  +  +                                                     + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +                                                     + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   18
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:04.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 5| 5| 8| 2| 2| 4| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 2| 2| 1| 8| 9| 7| 5| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 6| 6| 7| 7| 7| 8| 9| 0| 0| 0| 0| 0| 0| 5| 6| 9| 9| 9| 9| 0| 0| 0| 0| 6|   U      O|
50 MG/KGA 2YR  3     3                      | 5| 5| 9| 2| 3| 8| 1| 9| 0| 1| 2| 3| 4| 5| 4| 9| 6| 7| 8| 9| 0| 1| 2| 3| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM

HEART                                       | +  +  +  +  +  +  +                                                     + |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +                                                     + |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +                                                     + |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +                                                     + |          |
ISLETS, PANCREATIC                          | +  +  M  +  +  +  +                                                     + |          |
PARATHYROID GLAND                           | M  M  M  +  +  +  M                                                     + |          |
PITUITARY GLAND                             | +  +  +  +  +  M  M                                                     + |          |
  ADENOMA,PARS DISTALIS                     |                                                                           |          |
THYROID GLAND                               | +  +  +  +  +  +  M                                                     + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  M  A  +  +  +  +                                                  + |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
EPIDIDYMIS                                  | +  +  +  A  +  +  +                                                  +  + |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
  HISTIOCYTIC SARCOMA                       |                                                                      X    |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
PREPUTIAL GLAND                             | +  +  +  M  +  +  +              +              +                       + |          |
PROSTATE                                    | +  +  +  +  +  +  +                                                     + |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
SEMINAL VESICLE                             | +  +  +  M  +  +  +  +                                                  + |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
TESTES                                      | +  +  +  A  +  +  +                                                     + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   19
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:04.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 5| 5| 8| 2| 2| 4| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 2| 2| 1| 8| 9| 7| 5| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 6| 6| 7| 7| 7| 8| 9| 0| 0| 0| 0| 0| 0| 5| 6| 9| 9| 9| 9| 0| 0| 0| 0| 6|   U      O|
50 MG/KGA 2YR  3     3                      | 5| 5| 9| 2| 3| 8| 1| 9| 0| 1| 2| 3| 4| 5| 4| 9| 6| 7| 8| 9| 0| 1| 2| 3| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +                                                     + |          |
LYMPH NODE                                  | +  +  +  +  +  +  +        +     +     +                    +           + |          |
  SARCOMA,METASTATIC,UNCERTAIN PRIMARY SITE |                                                                           |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  A  +  +  +                                                     + |          |
  LYMPHOMA MALIGNANT                        | X  X  X                                                                   |          |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +        +     +     +                    +           + |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X  X                    X           X                                  |          |
SPLEEN                                      | +  +  +  +  +  A  +  +                 +                 +              + |          |
  HEMANGIOSARCOMA                           |                                                                           |          |
  LYMPHOMA MALIGNANT                        | X  X                                   X                                  |          |
THYMUS                                      | +  M  +  M  M  +  M                                                     M |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
  LYMPHOMA MALIGNANT                        | X     X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M  M  M  M                                                     M |          |
SKIN                                        | +  M  +  +  +  +  +                                                     + |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +                                                     + |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +                                                     + |          |
BONE,STERNUM                                | +  +  +  +  +  +  +                                                     + |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +                                                     + |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
  RHABDOMYOSARCOMA                          |                   X                                                       |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  A  +  +  +                                                     + |          |
BRAIN,CEREBELLUM                            | +  +  +  A  +  +  +                                                     + |          |
BRAIN,CEREBRUM                              | +  +  +  A  +  +  +                                                     + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   20
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:04.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 5| 5| 8| 2| 2| 4| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 2| 2| 1| 8| 9| 7| 5| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 6| 6| 7| 7| 7| 8| 9| 0| 0| 0| 0| 0| 0| 5| 6| 9| 9| 9| 9| 0| 0| 0| 0| 6|   U      O|
50 MG/KGA 2YR  3     3                      | 5| 5| 9| 2| 3| 8| 1| 9| 0| 1| 2| 3| 4| 5| 4| 9| 6| 7| 8| 9| 0| 1| 2| 3| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM

  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +                                                     + |          |
SPINAL CORD                                 | +  +  +  A  +  +  +                                                     + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +                                                     + |          |
LUNG                                        | +  +  +  +  +  +  +                             +                 +     + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                 X                 X       |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA,TWO          |                                                                           |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                                                           |          |
  CARCINOMA,METASTATIC,LIVER                |                X                                                          |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER,|             X                                                           X |          |
      MULTIPLE                              |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
NOSE                                        | +  +  +  +  +  +  +                                                     + |          |
  CARCINOMA                                 |                                                                           |          |
TRACHEA                                     | +  +  +  +  +  +  +                                                     + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +                                                     + |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +                             +                       + |          |
  ADENOMA                                   |                                                 X                         |          |
  LYMPHOMA MALIGNANT,BILATERAL              |    X                                                                      |          |
LACRIMAL GLAND                              | +  +  +  A  +  +  +                                                     + |          |
ZYMBAL'S GLAND                              | +  +  M  +  +  +  M                                                     + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +                                                     + |          |
  LYMPHOMA MALIGNANT                        |    X  X                                                                   |          |
URINARY BLADDER                             | +  +  +  +  +  +  +                                                     + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   21
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:06.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 2| 3| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 9| 7| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 6| 7| 7| 8| 9| 9| 0| 0| 0| 0| 0| 0| 0| 0| 7| 7| 9| 0| 0| 0| 0| 0| 0|         U      O|
50 MG/KGA 2YR  3     3                      | 7| 6| 7| 0| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 0| 1| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  A  +  +                                                                | 11       |
GALLBLADDER                                 | A  A  +  +                                                                | 10       |
INTESTINE LARGE                             | A  A  +  +                                                                |  4       |
INTESTINE LARGE,CECUM                       | A  A  +  +                                                                |  4       |
INTESTINE LARGE,COLON                       | A  A  +  +                                                                |  4       |
INTESTINE LARGE,RECTUM                      | A  A  +  +                                                                |  4       |
INTESTINE SMALL                             | A  A  +  +                                                                |  5       |
INTESTINE SMALL,DUODENUM                    | A  A  +  +                                                                |  4       |
INTESTINE SMALL,ILEUM                       | A  A  +  +                                                                |  5       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
INTESTINE SMALL,JEJUNUM                     | A  A  +  +                                                                |  4       |
LIVER                                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  CARCINOMA,BILE DUCT                       |                                                                           |         1|
  HEPATOCELLULAR ADENOMA,MULTIPLE           |                                                                           |         1|
  HEPATOCELLULAR ADENOMA,SINGLE             |       X     X     X        X           X                 X  X             |         9|
  HEPATOCELLULAR ADENOMA,THREE              |                                                                           |         2|
  HEPATOCELLULAR ADENOMA,TWO                |                         X     X     X                 X                   |         5|
  HEPATOCELLULAR CARCINOMA,SINGLE           | X                    X        X        X     X                            |         7|
  HEPATOCELLULAR CARCINOMA,THREE            |                                                                           |         2|
  HEPATOCELLULAR CARCINOMA,TWO              |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
MESENTERY                                   |                                                                           |  1       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PANCREAS                                    | A  A  +  +                                                                |  9       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
  NEOPLASM NOS                              |                                                                           |         1|
SALIVARY GLANDS                             | +  A  +  +                                                                | 10       |
STOMACH                                     | A  A  +  +                                                                | 10       |
STOMACH,FORESTOMACH                         | A  A  +  +                                                                | 10       |
STOMACH,GLANDULAR                           | A  A  +  +                                                                | 10       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
TONGUE                                      | +  A  +  +                                                                | 11       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  A  +  +                                                                | 11       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   22
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:06.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 2| 3| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 9| 7| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 6| 7| 7| 8| 9| 9| 0| 0| 0| 0| 0| 0| 0| 0| 7| 7| 9| 0| 0| 0| 0| 0| 0|         U      O|
50 MG/KGA 2YR  3     3                      | 7| 6| 7| 0| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 0| 1| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM

HEART                                       | +  A  +  +                                                                | 11       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | A  A  +  +                                                                | 10       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
ADRENAL GLAND,CORTEX                        | A  A  +  +                                                                | 10       |
ADRENAL GLAND,MEDULLA                       | A  A  +  +                                                                | 10       |
ISLETS, PANCREATIC                          | +  +  +  +                                                                | 11       |
PARATHYROID GLAND                           | +  A  M  +                                                                |  6       |
PITUITARY GLAND                             | A  A  +  +                 +                                              |  9       |
  ADENOMA,PARS DISTALIS                     |                            X                                              |         1|
THYROID GLAND                               | +  A  +  +                                                                | 10       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  A  +  +                                                                | 10       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
EPIDIDYMIS                                  | +  A  +  +                                                                | 11       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
PREPUTIAL GLAND                             | +  A  A  +                                                                | 11       |
PROSTATE                                    | +  A  +  +                                                                | 11       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
SEMINAL VESICLE                             | +  A  +  +                 +           +                       +          | 14       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
TESTES                                      | +  A  +  +                                                                | 10       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   23
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:06.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 2| 3| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 9| 7| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 6| 7| 7| 8| 9| 9| 0| 0| 0| 0| 0| 0| 0| 0| 7| 7| 9| 0| 0| 0| 0| 0| 0|         U      O|
50 MG/KGA 2YR  3     3                      | 7| 6| 7| 0| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 0| 1| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | A  A  +  +                                                                | 10       |
LYMPH NODE                                  | A  A  +  +                             +     +           +                | 17       |
  SARCOMA,METASTATIC,UNCERTAIN PRIMARY SITE |                                                          X                |         1|
LYMPH NODE,MANDIBULAR                       | M  A  +  +                                                                |  9       |
  LYMPHOMA MALIGNANT                        |                                                                           |         3|
LYMPH NODE,MESENTERIC                       | A  A  +  +                             +     +                            | 16       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                              X                            |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         4|
SPLEEN                                      | A  +  +  +              +  +     +              +                         | 17       |
  HEMANGIOSARCOMA                           |    X                             X                                        |         2|
  LYMPHOMA MALIGNANT                        |                                                                           |         3|
THYMUS                                      | M  M  M  +                                                                |  4       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M                                                                |  0       |
SKIN                                        | +  A  +  +                                                                | 10       |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +                                                                | 12       |
BONE,FEMUR                                  | +  +  +  +                                                                | 12       |
BONE,STERNUM                                | +  +  +  +                                                                | 12       |
SKELETAL MUSCLE                             | +  A  +  +                                                                | 11       |
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
  RHABDOMYOSARCOMA                          |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  A  A  +                                                                |  9       |
BRAIN,CEREBELLUM                            | +  A  A  +                                                                |  9       |
BRAIN,CEREBRUM                              | +  A  A  +                                                                |  9       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   24
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:06.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 2| 3| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 9| 7| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 6| 7| 7| 8| 9| 9| 0| 0| 0| 0| 0| 0| 0| 0| 7| 7| 9| 0| 0| 0| 0| 0| 0|         U      O|
50 MG/KGA 2YR  3     3                      | 7| 6| 7| 0| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 0| 1| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM

  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PERIPHERAL NERVE                            | +  A  +  +                                                                | 11       |
SPINAL CORD                                 | +  A  A  +                                                                |  9       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  A  +  +                                                                | 11       |
LUNG                                        | +  A  +  +  +                                            +  +             | 16       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                          X                |         3|
  ALVEOLAR/BRONCHIOLAR ADENOMA,TWO          |       X                                                                   |         1|
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |             X                                                             |         1|
  CARCINOMA,METASTATIC,LIVER                |                                                                           |         1|
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER,|                                                                           |         2|
      MULTIPLE                              |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
NOSE                                        | +  +  +  +                                                                | 12       |
  CARCINOMA                                 |       X                                                                   |         1|
TRACHEA                                     | +  A  +  +                                                                | 11       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  A  +  +                                                                | 11       |
HARDERIAN GLAND                             | +  A  +  +                                                                | 12       |
  ADENOMA                                   |       X                                                                   |         2|
  LYMPHOMA MALIGNANT,BILATERAL              |                                                                           |         1|
LACRIMAL GLAND                              | +  A  +  +                                                                | 10       |
ZYMBAL'S GLAND                              | M  A  M  +                                                                |  7       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | A  A  +  +                                                                | 10       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
URINARY BLADDER                             | +  A  +  +                                                                | 11       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   25
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:16.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 2| 6| 1| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 0| 2| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 6| 6| 7| 0| 0| 0| 0| 1| 1| 1| 1| 5| 5| 7| 7| 0| 0| 0| 0| 0| 0| 1| 1| 1| 6|   U      O|
100MG/KGA 2YR  4     4                      | 2| 7| 1| 6| 7| 8| 9| 0| 1| 2| 3| 6| 7| 0| 1| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
GALLBLADDER                                 | M  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |    X                                                                      |          |
INTESTINE LARGE                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE LARGE,CECUM                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
  LYMPHOMA MALIGNANT                        |                                                             X             |          |
INTESTINE LARGE,COLON                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE LARGE,RECTUM                      | M  A  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  A |          |
INTESTINE SMALL                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
INTESTINE SMALL,DUODENUM                    | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE SMALL,ILEUM                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
  ADENOCARCINOMA                            |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                  X              X                         |          |
INTESTINE SMALL,JEJUNUM                     | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA,SINGLE             |       X                             X     X           X  X        X       |          |
  HEPATOCELLULAR ADENOMA,THREE              |                                                                           |          |
  HEPATOCELLULAR ADENOMA,TWO                |                X                             X  X                         |          |
  HEPATOCELLULAR CARCINOMA,SINGLE           | X  X  X     X     X                                                       |          |
  HEPATOCELLULAR CARCINOMA,TWO              |                                           X                               |          |
  HISTIOCYTIC SARCOMA                       |                                           X                               |          |
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
STOMACH                                     | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
STOMACH,FORESTOMACH                         | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
STOMACH,GLANDULAR                           | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER,|    X                                                                      |          |
      AORTA                                 |                                                                           |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |    X  X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   26
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:16.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 2| 6| 1| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 0| 2| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 6| 6| 7| 0| 0| 0| 0| 1| 1| 1| 1| 5| 5| 7| 7| 0| 0| 0| 0| 0| 0| 1| 1| 1| 6|   U      O|
100MG/KGA 2YR  4     4                      | 2| 7| 1| 6| 7| 8| 9| 0| 1| 2| 3| 6| 7| 0| 1| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  + |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  M  +  +  +  +  + |          |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  M  +  +  +  +  + |          |
PITUITARY GLAND                             | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENERAL BODY SYSTEM

TISSUE NOS                                  |       +                                                                 + |          |
  HEMANGIOSARCOMA                           |                                                                         X |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER,|       X                                                                   |          |
      MEDIASTINUM                           |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
EPIDIDYMIS                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT,UNILATERAL             |                                                             X             |          |
  SCHWANNOMA BENIGN                         |                                              X                            |          |
PENIS                                       |                                                                         + |          |
PREPUTIAL GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PROSTATE                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |    X                                                                      |          |
SEMINAL VESICLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TESTES                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA,INTERSTITIAL CELL                 |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT,INGUINAL               |                                                             X             |          |
LYMPH NODE,MANDIBULAR                       | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                  X                          X             |          |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   27
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:17.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 2| 6| 1| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 0| 2| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 6| 6| 7| 0| 0| 0| 0| 1| 1| 1| 1| 5| 5| 7| 7| 0| 0| 0| 0| 0| 0| 1| 1| 1| 6|   U      O|
100MG/KGA 2YR  4     4                      | 2| 7| 1| 6| 7| 8| 9| 0| 1| 2| 3| 6| 7| 0| 1| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  HEMANGIOSARCOMA                           |                                                                         X |          |
  LYMPHOMA MALIGNANT                        |                                  X              X           X             |          |
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                                                                         X |          |
  LYMPHOMA MALIGNANT                        |                                  X                          X             |          |
THYMUS                                      | +  +  M  +  +  M  +  M  +  +  +  M  +  +  M  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |    X                                                                      |          |
  LYMPHOMA MALIGNANT                        |                                                             X             |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  +  M  +  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M |          |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  KERATOACANTHOMA                           |                                        X                                  |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                                                                         X |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  + |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                X                          X                 X           X |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   28
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:17.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 2| 6| 1| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 0| 2| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 6| 6| 7| 0| 0| 0| 0| 1| 1| 1| 1| 5| 5| 7| 7| 0| 0| 0| 0| 0| 0| 1| 1| 1| 6|   U      O|
100MG/KGA 2YR  4     4                      | 2| 7| 1| 6| 7| 8| 9| 0| 1| 2| 3| 6| 7| 0| 1| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

  ALVEOLAR/BRONCHIOLAR ADENOMA,TWO          |                         X                                                 |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                                    X                 X    |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |    X  X                                                                   |          |
  LYMPHOMA MALIGNANT                        |                                                             X             |          |
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT,UNILATERAL             |                                                                           |          |
HARDERIAN GLAND                             | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                                                                           |          |
LACRIMAL GLAND                              | +  M  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   29
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:25.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 5| 7| 7| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1|         U      O|
100MG/KGA 2YR  4     4                      | 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 9| 2| 3| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
GALLBLADDER                                 | +  +  +  +  +  +  +  +  +  +  +  M  M  +  +  +  +  +  +  +  +  +  +       | 44       |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         1|
INTESTINE LARGE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
INTESTINE LARGE,COLON                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  ADENOCARCINOMA                            |                                           X                               |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA,SINGLE             |       X                          X              X                 X       |        10|
  HEPATOCELLULAR ADENOMA,THREE              |                                                    X                      |         1|
  HEPATOCELLULAR ADENOMA,TWO                |    X                          X                             X             |         6|
  HEPATOCELLULAR CARCINOMA,SINGLE           |                                                       X                   |         6|
  HEPATOCELLULAR CARCINOMA,TWO              |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                     X                                     |         1|
STOMACH                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER,|                                                                           |         1|
      AORTA                                 |                                                                           |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   30
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:25.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 5| 7| 7| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1|         U      O|
100MG/KGA 2YR  4     4                      | 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 9| 2| 3| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +       | 46       |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +       | 46       |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +       | 45       |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PARATHYROID GLAND                           | +  +  +  M  M  +  +  +  +  +  M  +  +  +  M  +  +  +  +  +  +  +  +       | 42       |
PITUITARY GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +       | 46       |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
GENERAL BODY SYSTEM

TISSUE NOS                                  |                                                                           |  2       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER,|                                                                           |         1|
      MEDIASTINUM                           |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
EPIDIDYMIS                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT,UNILATERAL             |                                                                           |         1|
  SCHWANNOMA BENIGN                         |                                                                           |         1|
PENIS                                       |                                                                           |  1       |
PREPUTIAL GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PROSTATE                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         1|
SEMINAL VESICLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TESTES                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ADENOMA,INTERSTITIAL CELL                 |                                                             X             |         1|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT,INGUINAL               |                                                                           |         1|
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  M  M  +  +  +  +  +  +  +  +       | 45       |
  LYMPHOMA MALIGNANT                        |                                     X                                     |         3|
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   31
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:25.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 5| 7| 7| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1|         U      O|
100MG/KGA 2YR  4     4                      | 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 9| 2| 3| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  HEMANGIOSARCOMA                           |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                     X                                     |         4|
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA                           |                                        X                                  |         2|
  LYMPHOMA MALIGNANT                        |                                     X                                     |         3|
THYMUS                                      | +  M  +  M  +  +  +  M  +  M  +  M  +  +  M  +  +  +  M  +  +  M  +       | 35       |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                     X                                     |         2|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M       |  2       |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  KERATOACANTHOMA                           |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                     X                                     |         1|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |       X                                   X        X  X     X             |         9|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   32
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:25.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 5| 7| 7| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1|         U      O|
100MG/KGA 2YR  4     4                      | 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 9| 2| 3| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

  ALVEOLAR/BRONCHIOLAR ADENOMA,TWO          |                               X                                           |         2|
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                              X                            |         3|
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         2|
  LYMPHOMA MALIGNANT                        |                                     X                                     |         2|
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT,UNILATERAL             |                                     X                                     |         1|
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  ADENOMA                                   |                   X                                X  X  X        X       |         5|
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                     X                                     |         1|
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                     X                                     |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   33
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:26.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 2| 2| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3|                                          S      M|
                                            | 0| 1| 1| 3| 3| 3| 1| 1| 1| 3| 3| 3|                                          U      O|
CONTROL A 64WK 5     5                      | 9| 0| 1| 4| 5| 6| 1| 2| 3| 5| 6| 7|                                          E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +                                        | 12       |
  HEPATOCELLULAR ADENOMA,SINGLE             | X                       X                                                 |         2|
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   34
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:26.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 2| 2| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3|                                          S      M|
                                            | 1| 1| 1| 3| 3| 3| 1| 1| 1| 3| 3| 4|                                          U      O|
25MG/KG A 64W 6      6                      | 2| 3| 4| 7| 8| 9| 4| 5| 6| 8| 9| 0|                                          E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +                                        | 12       |
  HEPATOCELLULAR ADENOMA,SINGLE             |          X     X                                                          |         2|
  HEPATOCELLULAR CARCINOMA,SINGLE           |             X                                                             |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   35
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:26.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 2| 2| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3|                                          S      M|
                                            | 1| 1| 1| 4| 4| 4| 1| 1| 1| 4| 4| 4|                                          U      O|
50 MG/KGA 64W  7     7                      | 5| 6| 7| 0| 1| 2| 7| 8| 9| 1| 2| 3|                                          E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +                                        | 12       |
  HEPATOCELLULAR ADENOMA,SINGLE             |          X  X                                                             |         2|
  HEPATOCELLULAR ADENOMA,TWO                |                X                                                          |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   36
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:27.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 2| 2| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3|                                          S      M|
                                            | 1| 1| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4|                                          U      O|
100MG/KGA 64W  8     8                      | 8| 9| 0| 3| 4| 5| 0| 1| 2| 4| 5| 6|                                          E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +                                        | 12       |
  HEPATOCELLULAR ADENOMA,SINGLE             |    X                                                                      |         1|
  HEPATOCELLULAR CARCINOMA,SINGLE           | X              X                                                          |         2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   37
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:33.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
                                            | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 4|
                                            | 3| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 8| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 5| 5| 7| 7| 1| 1| 1| 1| 1| 1| 1| 2| 2| 0|   U      O|
CONTROL R 2YR 10    10                      | 0| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 5| 8| 2| 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  + |          |
GALLBLADDER                                 | +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +  +  +  +  M  M  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,COLON                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |       X                                                                   |          |
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X                                                       |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA,SINGLE             |                                        X  X  X           X                |          |
  HEPATOCELLULAR ADENOMA,TWO                |                                                                           |          |
  HEPATOCELLULAR CARCINOMA,SINGLE           |       X                                                                   |          |
  HISTIOCYTIC SARCOMA                       | X                 X                                                       |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   38
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:33.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
                                            | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 4|
                                            | 3| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 8| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 5| 5| 7| 7| 1| 1| 1| 1| 1| 1| 1| 2| 2| 0|   U      O|
CONTROL R 2YR 10    10                      | 0| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 5| 8| 2| 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  M  +  +  +  +  M  M |          |
PITUITARY GLAND                             | +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  + |          |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
EPIDIDYMIS                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PREPUTIAL GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PROSTATE                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
SEMINAL VESICLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TESTES                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |                                           X                               |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
LYMPH NODE,MESENTERIC                       | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X                                                     X |          |
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |             X                                                             |          |
  LYMPHOMA MALIGNANT                        |                   X                       X                             X |          |
THYMUS                                      | +  +  M  +  +  +  +  +  +  +  +  M  M  +  +  +  +  +  +  +  +  +  +  M  M |          |
  LYMPHOMA MALIGNANT                        |                   X                                                       |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M |          |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |             X                                                             |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   39
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:33.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
                                            | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 4|
                                            | 3| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 8| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 5| 5| 7| 7| 1| 1| 1| 1| 1| 1| 1| 2| 2| 0|   U      O|
CONTROL R 2YR 10    10                      | 0| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 5| 8| 2| 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  M |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                      X  X                 X           X           X  X    |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                                                           |          |
  HISTIOCYTIC SARCOMA                       | X                                                                         |          |
  LYMPHOMA MALIGNANT                        |                                                                         X |          |
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                                  X           X                            |          |
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ZYMBAL'S GLAND                              | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   40
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:33.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
                                            | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 4|
                                            | 3| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 8| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 5| 5| 7| 7| 1| 1| 1| 1| 1| 1| 1| 2| 2| 0|   U      O|
CONTROL R 2YR 10    10                      | 0| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 5| 8| 2| 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   41
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:39.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 1| 1| 2| 2| 2| 2| 2| 2| 2| 6| 6| 7| 7| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2|         U      O|
CONTROL R 2YR 10    10                      | 8| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 4| 5| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
GALLBLADDER                                 | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE LARGE                             | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
INTESTINE LARGE,CECUM                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
INTESTINE LARGE,COLON                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
INTESTINE LARGE,RECTUM                      | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
INTESTINE SMALL,DUODENUM                    | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  ADENOMA                                   |                                                                           |         1|
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        | X                                                                         |         1|
INTESTINE SMALL,JEJUNUM                     | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA,SINGLE             |             X     X              X                                        |         7|
  HEPATOCELLULAR ADENOMA,TWO                |                      X                                            X       |         2|
  HEPATOCELLULAR CARCINOMA,SINGLE           |                                                          X                |         2|
  HISTIOCYTIC SARCOMA                       |                                                                           |         2|
  LYMPHOMA MALIGNANT                        | X                                                                         |         1|
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        | X                                                                         |         1|
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
STOMACH                                     | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
STOMACH,FORESTOMACH                         | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
STOMACH,GLANDULAR                           | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +       | 45       |
ADRENAL GLAND,CORTEX                        | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +       | 45       |
ADRENAL GLAND,MEDULLA                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +       | 45       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   42
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:39.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 1| 1| 2| 2| 2| 2| 2| 2| 2| 6| 6| 7| 7| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2|         U      O|
CONTROL R 2YR 10    10                      | 8| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 4| 5| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
PITUITARY GLAND                             | A  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  M  +  +  +  +  +       | 43       |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
EPIDIDYMIS                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PREPUTIAL GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PROSTATE                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
SEMINAL VESICLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TESTES                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
LYMPH NODE                                  | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT,LUMBAR                 |                                                                           |         1|
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  M  M  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
  LYMPHOMA MALIGNANT                        | X                                                                         |         3|
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
  LYMPHOMA MALIGNANT                        | X              X  X                                                       |         6|
THYMUS                                      | M  +  +  M  +  +  +  +  M  +  +  +  +  M  +  +  +  +  +  +  +  +  +       | 39       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M       |  0       |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   43
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:39.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 1| 1| 2| 2| 2| 2| 2| 2| 2| 6| 6| 7| 7| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2|         U      O|
CONTROL R 2YR 10    10                      | 8| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 4| 5| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                X              X        X                                  |         9|
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                      X                          X                         |         2|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                X                                                          |         2|
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ADENOMA                                   |                               X                             X             |         4|
LACRIMAL GLAND                              | +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   44
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:39.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 1| 1| 2| 2| 2| 2| 2| 2| 2| 6| 6| 7| 7| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2|         U      O|
CONTROL R 2YR 10    10                      | 8| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 4| 5| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   45
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:40.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 1| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1|
                                            | 4| 4| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 6| 2| 2| 2| 2| 2| 2| 3| 3| 3| 5| 6| 7| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 6|   U      O|
25MG/KG R 2YR 11    11                      | 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 9| 0| 4| 5| 2| 3| 4| 5| 6| 7| 8| 9| 0| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +                                                                    + |          |
GALLBLADDER                                 | +  +                                                                    + |          |
INTESTINE LARGE                             | +  +                                                                    + |          |
INTESTINE LARGE,CECUM                       | +  +                                                                    + |          |
INTESTINE LARGE,COLON                       | +  +                                                                    + |          |
  HISTIOCYTIC SARCOMA                       |                                                                         X |          |
INTESTINE LARGE,RECTUM                      | +  +                                                                    + |          |
INTESTINE SMALL                             | +  +                                                           +        + |          |
INTESTINE SMALL,DUODENUM                    | +  +                                                                    + |          |
  HEMANGIOSARCOMA                           |                                                                           |          |
INTESTINE SMALL,ILEUM                       | +  +                                                                    + |          |
  HISTIOCYTIC SARCOMA                       |                                                                         X |          |
INTESTINE SMALL,JEJUNUM                     | +  +                                                           +        + |          |
  LYMPHOMA MALIGNANT                        |    X                                                           X          |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA,SINGLE             |             X  X  X  X                    X  X           X                |          |
  HEPATOCELLULAR CARCINOMA,SINGLE           |             X                                                             |          |
  HEPATOCELLULAR CARCINOMA,TWO              |                                                                           |          |
  HISTIOCYTIC SARCOMA                       |                                                                         X |          |
  LEUKEMIA GRANULOCYTIC                     |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
PANCREAS                                    | +  +                                                                    + |          |
SALIVARY GLANDS                             | +  +                                                                    + |          |
STOMACH                                     | +  +                                                                    + |          |
STOMACH,FORESTOMACH                         | +  +                                                                    + |          |
STOMACH,GLANDULAR                           | +  +                                                                    + |          |
TONGUE                                      | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +                                                                    + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
HEART                                       | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   46
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:40.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 1| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1|
                                            | 4| 4| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 6| 2| 2| 2| 2| 2| 2| 3| 3| 3| 5| 6| 7| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 6|   U      O|
25MG/KG R 2YR 11    11                      | 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 9| 0| 4| 5| 2| 3| 4| 5| 6| 7| 8| 9| 0| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +                                                                    + |          |
ADRENAL GLAND,CORTEX                        | +  +                                                                    + |          |
ADRENAL GLAND,MEDULLA                       | +  +                                                                    + |          |
ISLETS, PANCREATIC                          | +  +                                                                    + |          |
PARATHYROID GLAND                           | +  +                                                                    + |          |
PITUITARY GLAND                             | +  M                                                                    + |          |
  ADENOMA,PARS DISTALIS                     |                                                                           |          |
THYROID GLAND                               | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +                                                                    + |          |
EPIDIDYMIS                                  | +  +                                                                    + |          |
PREPUTIAL GLAND                             | +  +                                                                    + |          |
PROSTATE                                    | +  +                                                                    + |          |
  HISTIOCYTIC SARCOMA                       |                                                                         X |          |
SEMINAL VESICLE                             | +  +                                                                    + |          |
TESTES                                      | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +                                                                    + |          |
LYMPH NODE                                  | +  +                 +                                         +        + |          |
  HISTIOCYTIC SARCOMA,RENAL                 |                                                                         X |          |
  LYMPHOMA MALIGNANT,RENAL                  |                      X                                                    |          |
LYMPH NODE,MANDIBULAR                       | +  M                                                                    + |          |
LYMPH NODE,MESENTERIC                       | +  +                 +                                         +        + |          |
  HISTIOCYTIC SARCOMA                       |                                                                         X |          |
  LYMPHOMA MALIGNANT                        |    X                 X                                         X          |          |
SPLEEN                                      | +  +                                                           +        M |          |
  LEUKEMIA GRANULOCYTIC                     |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
THYMUS                                      | M  +                                                                    + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   47
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:41.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 1| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1|
                                            | 4| 4| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 6| 2| 2| 2| 2| 2| 2| 3| 3| 3| 5| 6| 7| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 6|   U      O|
25MG/KG R 2YR 11    11                      | 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 9| 0| 4| 5| 2| 3| 4| 5| 6| 7| 8| 9| 0| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M                                                                    M |          |
SKIN                                        | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +                                                                    + |          |
BONE,FEMUR                                  | +  +                                                                    + |          |
BONE,STERNUM                                | +  +                                                                    + |          |
SKELETAL MUSCLE                             | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +                                                                    + |          |
BRAIN,CEREBELLUM                            | +  +                                                                    + |          |
BRAIN,CEREBRUM                              | +  +                                                                    + |          |
PERIPHERAL NERVE                            | +  +                                                                    + |          |
SPINAL CORD                                 | M  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +                                                                    + |          |
LUNG                                        | +  +                                               +                    + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                    X                      |          |
  CARCINOMA,METASTATIC,HARDERIAN GLAND      |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
NOSE                                        | +  +                                                                    + |          |
TRACHEA                                     | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EAR                                         |                         +                                                 |          |
  FIBROUS HISTIOCYTOMA                      |                         X                                                 |          |
EYE                                         | +  +                                                                    + |          |
HARDERIAN GLAND                             | +  +                                   +                                + |          |
  ADENOMA                                   |                                        X                                  |          |
  CARCINOMA                                 |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   48
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:41.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 1| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 8| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1|
                                            | 4| 4| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 6| 2| 2| 2| 2| 2| 2| 3| 3| 3| 5| 6| 7| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 6|   U      O|
25MG/KG R 2YR 11    11                      | 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 9| 0| 4| 5| 2| 3| 4| 5| 6| 7| 8| 9| 0| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

LACRIMAL GLAND                              | +  +                                                                    + |          |
ZYMBAL'S GLAND                              | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +                                                                    + |          |
URINARY BLADDER                             | +  +                                                                    + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   49
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:41.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 7| 2| 2| 2| 3| 3| 3| 3| 3| 3| 6| 6| 7| 7| 2| 2| 2| 3| 3| 3| 3| 3| 3|         U      O|
25MG/KG R 2YR 11    11                      | 2| 7| 8| 9| 0| 1| 2| 3| 4| 5| 2| 3| 6| 7| 7| 8| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +                                                                         |  4       |
GALLBLADDER                                 | +                                                                         |  4       |
INTESTINE LARGE                             | +                                                                         |  4       |
INTESTINE LARGE,CECUM                       | +                                                                         |  4       |
INTESTINE LARGE,COLON                       | +                                                                         |  4       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
INTESTINE LARGE,RECTUM                      | +                                                                         |  4       |
INTESTINE SMALL                             | +                                                                         |  5       |
INTESTINE SMALL,DUODENUM                    | +                                                                         |  4       |
  HEMANGIOSARCOMA                           | X                                                                         |         1|
INTESTINE SMALL,ILEUM                       | +                                                                         |  4       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
INTESTINE SMALL,JEJUNUM                     | +                                                                         |  5       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA,SINGLE             |                                                                           |         7|
  HEPATOCELLULAR CARCINOMA,SINGLE           |       X                    X                                              |         3|
  HEPATOCELLULAR CARCINOMA,TWO              |                                  X        X                               |         2|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LEUKEMIA GRANULOCYTIC                     |                                                          X                |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PANCREAS                                    | +                                                                         |  4       |
SALIVARY GLANDS                             | +                                                                         |  4       |
STOMACH                                     | +                                               +                         |  5       |
STOMACH,FORESTOMACH                         | +                                               +                         |  5       |
STOMACH,GLANDULAR                           | +                                               +                         |  5       |
TONGUE                                      | +                                                                         |  4       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +                                                                         |  4       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
HEART                                       | +                                                                         |  4       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   50
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:41.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 7| 2| 2| 2| 3| 3| 3| 3| 3| 3| 6| 6| 7| 7| 2| 2| 2| 3| 3| 3| 3| 3| 3|         U      O|
25MG/KG R 2YR 11    11                      | 2| 7| 8| 9| 0| 1| 2| 3| 4| 5| 2| 3| 6| 7| 7| 8| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +                                                                         |  4       |
ADRENAL GLAND,CORTEX                        | +                                                                         |  4       |
ADRENAL GLAND,MEDULLA                       | +                                                                         |  4       |
ISLETS, PANCREATIC                          | +                                                                         |  4       |
PARATHYROID GLAND                           | M                                                                         |  3       |
PITUITARY GLAND                             | M                                      +                                  |  3       |
  ADENOMA,PARS DISTALIS                     |                                        X                                  |         1|
THYROID GLAND                               | +                                                                         |  4       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +                                                                         |  4       |
EPIDIDYMIS                                  | +                                                                         |  4       |
PREPUTIAL GLAND                             | +                                                                         |  4       |
PROSTATE                                    | +                                                                         |  4       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
SEMINAL VESICLE                             | +                                                                         |  4       |
TESTES                                      | +                                                                         |  4       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +                                                                         |  4       |
LYMPH NODE                                  | +                                      +     +                            |  8       |
  HISTIOCYTIC SARCOMA,RENAL                 |                                                                           |         1|
  LYMPHOMA MALIGNANT,RENAL                  |                                                                           |         1|
LYMPH NODE,MANDIBULAR                       | +                                                                         |  3       |
LYMPH NODE,MESENTERIC                       | +                                      +     +                            |  8       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                              X                            |         4|
SPLEEN                                      | +     +                    +                 +           +                |  8       |
  LEUKEMIA GRANULOCYTIC                     |                                                          X                |         1|
  LYMPHOMA MALIGNANT                        |                                              X                            |         2|
THYMUS                                      | M                                                                         |  2       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   51
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:41.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 7| 2| 2| 2| 3| 3| 3| 3| 3| 3| 6| 6| 7| 7| 2| 2| 2| 3| 3| 3| 3| 3| 3|         U      O|
25MG/KG R 2YR 11    11                      | 2| 7| 8| 9| 0| 1| 2| 3| 4| 5| 2| 3| 6| 7| 7| 8| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M                                                                         |  0       |
SKIN                                        | +                                                                         |  4       |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +                                                                         |  4       |
BONE,FEMUR                                  | +                                                                         |  4       |
BONE,STERNUM                                | +                                                                         |  4       |
SKELETAL MUSCLE                             | +                                                                         |  4       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +                                                                         |  4       |
BRAIN,CEREBELLUM                            | +                                                                         |  4       |
BRAIN,CEREBRUM                              | +                                                                         |  4       |
PERIPHERAL NERVE                            | +                                                                         |  4       |
SPINAL CORD                                 | +                                                                         |  3       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +                                                                         |  4       |
LUNG                                        | +                                                  +                      |  6       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                                           |         1|
  CARCINOMA,METASTATIC,HARDERIAN GLAND      |                                                    X                      |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
NOSE                                        | +                                                                         |  4       |
TRACHEA                                     | +                                                                         |  4       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EAR                                         |                                                                           |  1       |
  FIBROUS HISTIOCYTOMA                      |                                                                           |         1|
EYE                                         | +                                                                         |  4       |
HARDERIAN GLAND                             | +                    +  +                          +                      |  8       |
  ADENOMA                                   |                      X  X                                                 |         3|
  CARCINOMA                                 |                                                    X                      |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   52
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:42.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 7| 2| 2| 2| 3| 3| 3| 3| 3| 3| 6| 6| 7| 7| 2| 2| 2| 3| 3| 3| 3| 3| 3|         U      O|
25MG/KG R 2YR 11    11                      | 2| 7| 8| 9| 0| 1| 2| 3| 4| 5| 2| 3| 6| 7| 7| 8| 9| 0| 1| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

LACRIMAL GLAND                              | +                                                                         |  4       |
ZYMBAL'S GLAND                              | M                                                                         |  3       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +                                                                         |  4       |
URINARY BLADDER                             | +                                                                         |  4       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   53
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:42.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 4|   S      M|
                                            | 0| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|   U      O|
50 MG/KGR 2YR 12    12                      | 6| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 1| 2| 6| 7| 1| 2| 3| 4| 5| 6| 7| 8| 9| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +                                                                         |          |
GALLBLADDER                                 | +                                                                         |          |
INTESTINE LARGE                             | +                                                                         |          |
INTESTINE LARGE,CECUM                       | +                                                                         |          |
INTESTINE LARGE,COLON                       | +                                                                         |          |
INTESTINE LARGE,RECTUM                      | +                                                                         |          |
INTESTINE SMALL                             | +                                                                         |          |
INTESTINE SMALL,DUODENUM                    | +                                                                         |          |
INTESTINE SMALL,ILEUM                       | +                                                                         |          |
INTESTINE SMALL,JEJUNUM                     | +                                                                         |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA,SINGLE             |             X  X        X           X              X     X     X          |          |
  HEPATOCELLULAR CARCINOMA,SINGLE           |    X                                                                      |          |
  HEPATOCELLULAR CARCINOMA,TWO              |                                                                           |          |
PANCREAS                                    | +                                                                         |          |
SALIVARY GLANDS                             | +                                                                         |          |
STOMACH                                     | +                                                                         |          |
STOMACH,FORESTOMACH                         | +                                                                         |          |
STOMACH,GLANDULAR                           | +                                                                         |          |
TONGUE                                      | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +                                                                         |          |
HEART                                       | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +                                                                         |          |
ADRENAL GLAND,CORTEX                        | +                                                                         |          |
ADRENAL GLAND,MEDULLA                       | +                                                                         |          |
ISLETS, PANCREATIC                          | +                                                                         |          |
PARATHYROID GLAND                           | M                                                                         |          |
PITUITARY GLAND                             | +                                                                         |          |
THYROID GLAND                               | M                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   54
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:42.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 4|   S      M|
                                            | 0| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|   U      O|
50 MG/KGR 2YR 12    12                      | 6| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 1| 2| 6| 7| 1| 2| 3| 4| 5| 6| 7| 8| 9| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM

COAGULATING GLAND                           | +                                                                         |          |
EPIDIDYMIS                                  | +                                                                         |          |
PREPUTIAL GLAND                             | +                                                                         |          |
PROSTATE                                    | +                                                                         |          |
SEMINAL VESICLE                             | +                                                                         |          |
TESTES                                      | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +                                                                         |          |
LYMPH NODE                                  | +                                                                         |          |
LYMPH NODE,MANDIBULAR                       | +                                                                         |          |
LYMPH NODE,MESENTERIC                       | +                                                                         |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
SPLEEN                                      | +                                                                         |          |
  HEMANGIOSARCOMA                           |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
THYMUS                                      | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M                                                                         |          |
SKIN                                        | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +                                                                         |          |
BONE,FEMUR                                  | +                                                                         |          |
BONE,STERNUM                                | +                                                                         |          |
SKELETAL MUSCLE                             | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +                                                                         |          |
BRAIN,CEREBELLUM                            | +                                                                         |          |
BRAIN,CEREBRUM                              | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   55
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:42.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 4|   S      M|
                                            | 0| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|   U      O|
50 MG/KGR 2YR 12    12                      | 6| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 1| 2| 6| 7| 1| 2| 3| 4| 5| 6| 7| 8| 9| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM

PERIPHERAL NERVE                            | +                                                                         |          |
SPINAL CORD                                 | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +                                                                         |          |
LUNG                                        | +              +                                                          |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                X                                                          |          |
NOSE                                        | +                                                                         |          |
TRACHEA                                     | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +                                                                         |          |
HARDERIAN GLAND                             | +                                                                         |          |
  ADENOMA                                   |                                                                           |          |
LACRIMAL GLAND                              | +                                                                         |          |
ZYMBAL'S GLAND                              | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +                                                                         |          |
URINARY BLADDER                             | +                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   56
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:43.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 3| 3| 3| 4| 4| 4| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5|         U      O|
50 MG/KGR 2YR 12    12                      | 7| 8| 9| 0| 1| 2| 3| 4| 5| 4| 5| 8| 9| 6| 7| 8| 9| 0| 1| 2| 3| 4| 4|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   |                                                                           |  1       |
GALLBLADDER                                 |                                                                           |  1       |
INTESTINE LARGE                             |                                                                           |  1       |
INTESTINE LARGE,CECUM                       |                                                                           |  1       |
INTESTINE LARGE,COLON                       |                                                                           |  1       |
INTESTINE LARGE,RECTUM                      |                                                                           |  1       |
INTESTINE SMALL                             |                                                                           |  1       |
INTESTINE SMALL,DUODENUM                    |                                                                           |  1       |
INTESTINE SMALL,ILEUM                       |                                                                           |  1       |
INTESTINE SMALL,JEJUNUM                     |                                                                           |  1       |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA,SINGLE             |       X        X                                               X          |        10|
  HEPATOCELLULAR CARCINOMA,SINGLE           | X                       X                                                 |         3|
  HEPATOCELLULAR CARCINOMA,TWO              |                                              X                            |         1|
PANCREAS                                    |                                                                           |  1       |
SALIVARY GLANDS                             |                                                                           |  1       |
STOMACH                                     |                                                                           |  1       |
STOMACH,FORESTOMACH                         |                                                                           |  1       |
STOMACH,GLANDULAR                           |                                                                           |  1       |
TONGUE                                      |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                |                                                                           |  1       |
HEART                                       |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               |                                                                           |  1       |
ADRENAL GLAND,CORTEX                        |                                                                           |  1       |
ADRENAL GLAND,MEDULLA                       |                                                                           |  1       |
ISLETS, PANCREATIC                          |                                                                           |  1       |
PARATHYROID GLAND                           |                                                                           |  0       |
PITUITARY GLAND                             |                                                                           |  1       |
THYROID GLAND                               |                                                                           |  0       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   57
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:43.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 3| 3| 3| 4| 4| 4| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5|         U      O|
50 MG/KGR 2YR 12    12                      | 7| 8| 9| 0| 1| 2| 3| 4| 5| 4| 5| 8| 9| 6| 7| 8| 9| 0| 1| 2| 3| 4| 4|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM

COAGULATING GLAND                           |                                                                           |  1       |
EPIDIDYMIS                                  |                                                                           |  1       |
PREPUTIAL GLAND                             |                                                                           |  1       |
PROSTATE                                    |                                                                           |  1       |
SEMINAL VESICLE                             |                                                                           |  1       |
TESTES                                      |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 |                                                                           |  1       |
LYMPH NODE                                  | +                                         +                               |  3       |
LYMPH NODE,MANDIBULAR                       |                                                                           |  1       |
LYMPH NODE,MESENTERIC                       | +                                         +                               |  3       |
  LYMPHOMA MALIGNANT                        | X                                                                         |         1|
SPLEEN                                      | +  +                                         +                            |  4       |
  HEMANGIOSARCOMA                           |    X                                                                      |         1|
  LYMPHOMA MALIGNANT                        | X                                                                         |         1|
THYMUS                                      |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               |                                                                           |  0       |
SKIN                                        |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        |                                                                           |  1       |
BONE,FEMUR                                  |                                                                           |  1       |
BONE,STERNUM                                |                                                                           |  1       |
SKELETAL MUSCLE                             |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       |                                                                           |  1       |
BRAIN,CEREBELLUM                            |                                                                           |  1       |
BRAIN,CEREBRUM                              |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   58
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:43.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 3| 3| 3| 4| 4| 4| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5|         U      O|
50 MG/KGR 2YR 12    12                      | 7| 8| 9| 0| 1| 2| 3| 4| 5| 4| 5| 8| 9| 6| 7| 8| 9| 0| 1| 2| 3| 4| 4|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM

PERIPHERAL NERVE                            |                                                                           |  1       |
SPINAL CORD                                 |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      |                                                                           |  1       |
LUNG                                        |                               +                 +              +          |  5       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                               X                                X          |         3|
NOSE                                        |                                                                           |  1       |
TRACHEA                                     |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         |                                                                           |  1       |
HARDERIAN GLAND                             |                                              +                            |  2       |
  ADENOMA                                   |                                              X                            |         1|
LACRIMAL GLAND                              |                                                                           |  1       |
ZYMBAL'S GLAND                              |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      |                                                                           |  1       |
URINARY BLADDER                             |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   59
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:50.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 4| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 1| 8| 2| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
                                            | 1| 5| 8| 4| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 2| 6| 7| 4| 4| 4| 4| 4| 4| 4| 5| 6| 6| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| 6|   U      O|
100MG/KGR 2YR 13    13                      | 4| 1| 1| 7| 3| 4| 5| 6| 7| 8| 9| 0| 3| 4| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 1|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
GALLBLADDER                                 | +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,CECUM                       | +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE LARGE,COLON                       | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE LARGE,RECTUM                      | +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL                             | +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE SMALL,DUODENUM                    | +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE SMALL,ILEUM                       | +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE SMALL,JEJUNUM                     | +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |       X                                                                   |          |
  HEPATOCELLULAR ADENOMA,SINGLE             |                                  X                                X     X |          |
  HEPATOCELLULAR ADENOMA,TWO                |                                                 X                         |          |
  HEPATOCELLULAR CARCINOMA,FOUR             |                                                                           |          |
  HEPATOCELLULAR CARCINOMA,SINGLE           |    X     X     X                                                          |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
STOMACH                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   60
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:50.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 4| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 1| 8| 2| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
                                            | 1| 5| 8| 4| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 2| 6| 7| 4| 4| 4| 4| 4| 4| 4| 5| 6| 6| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| 6|   U      O|
100MG/KGR 2YR 13    13                      | 4| 1| 1| 7| 3| 4| 5| 6| 7| 8| 9| 0| 3| 4| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 1|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  + |          |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  + |          |
PITUITARY GLAND                             | M  +  M  +  +  +  M  +  M  +  +  +  +  +  +  +  M  +  +  +  +  M  M  +  M |          |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
EPIDIDYMIS                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROMA                                   |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
PREPUTIAL GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PROSTATE                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  M  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
SEMINAL VESICLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TESTES                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT,AXILLARY               |                                                                           |          |
  LYMPHOMA MALIGNANT,INGUINAL               |                                                                           |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |                                                                           |          |
  LYMPHOMA MALIGNANT,POPLITEAL              |                                                                           |          |
  LYMPHOMA MALIGNANT,RENAL                  |                                                                           |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                   X                                         X             |          |
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   61
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:50.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 4| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 1| 8| 2| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
                                            | 1| 5| 8| 4| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 2| 6| 7| 4| 4| 4| 4| 4| 4| 4| 5| 6| 6| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| 6|   U      O|
100MG/KGR 2YR 13    13                      | 4| 1| 1| 7| 3| 4| 5| 6| 7| 8| 9| 0| 3| 4| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 1|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  HEMANGIOSARCOMA                           |       X                                                                   |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                   X                                                       |          |
THYMUS                                      | +  M  A  M  +  +  M  +  +  +  +  M  M  +  M  +  M  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M |          |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBRUM                              | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                 X        X  X             |          |
  CARCINOMA,METASTATIC,HARDERIAN GLAND      |                                                                           |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |          X                                                                |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   62
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:50.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 4| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
                                            | 1| 8| 2| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
                                            | 1| 5| 8| 4| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 0| 2| 6| 7| 4| 4| 4| 4| 4| 4| 4| 5| 6| 6| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| 6|   U      O|
100MG/KGR 2YR 13    13                      | 4| 1| 1| 7| 3| 4| 5| 6| 7| 8| 9| 0| 3| 4| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 1|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                                              X        X                   |          |
  CARCINOMA                                 |                                                                           |          |
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  M  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
ZYMBAL'S GLAND                              | +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   63
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:57.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 2| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 7| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 8| 8| 4| 4| 4| 4| 4| 5| 5| 5| 5|         U      O|
100MG/KGR 2YR 13    13                      | 8| 6| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 0| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
GALLBLADDER                                 | A  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  M  +  +       | 43       |
INTESTINE LARGE                             | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
INTESTINE LARGE,CECUM                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
INTESTINE LARGE,COLON                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
INTESTINE LARGE,RECTUM                      | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE SMALL                             | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
INTESTINE SMALL,DUODENUM                    | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
INTESTINE SMALL,ILEUM                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
INTESTINE SMALL,JEJUNUM                     | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA                           |                                                          X                |         2|
  HEPATOCELLULAR ADENOMA,SINGLE             |             X           X     X  X                 X           X          |         9|
  HEPATOCELLULAR ADENOMA,TWO                |                                                                           |         1|
  HEPATOCELLULAR CARCINOMA,FOUR             |                                                             X             |         1|
  HEPATOCELLULAR CARCINOMA,SINGLE           | X                                      X        X        X                |         7|
  HISTIOCYTIC SARCOMA                       |    X                                      X                               |         2|
  LYMPHOMA MALIGNANT                        |                      X                 X                                  |         2|
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
STOMACH                                     | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
STOMACH,FORESTOMACH                         | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
STOMACH,GLANDULAR                           | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA                       |    X                                                                      |         1|
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA                       |    X                                                                      |         1|
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   64
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:57.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 2| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 7| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 8| 8| 4| 4| 4| 4| 4| 5| 5| 5| 5|         U      O|
100MG/KGR 2YR 13    13                      | 8| 6| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 0| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
PITUITARY GLAND                             | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +       | 38       |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
EPIDIDYMIS                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  FIBROMA                                   |                                                                   X       |         1|
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
PREPUTIAL GLAND                             | +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
PROSTATE                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
SEMINAL VESICLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TESTES                                      | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT,AXILLARY               |                                        X                                  |         1|
  LYMPHOMA MALIGNANT,INGUINAL               |                                        X                                  |         1|
  LYMPHOMA MALIGNANT,LUMBAR                 |                                        X                                  |         1|
  LYMPHOMA MALIGNANT,POPLITEAL              |                                        X                                  |         1|
  LYMPHOMA MALIGNANT,RENAL                  |                                        X                                  |         1|
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA                       |    X  X                                   X                               |         3|
  LYMPHOMA MALIGNANT                        |                                        X                                  |         3|
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   65
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:57.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 2| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 7| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 8| 8| 4| 4| 4| 4| 4| 5| 5| 5| 5|         U      O|
100MG/KGR 2YR 13    13                      | 8| 6| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 0| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  HEMANGIOSARCOMA                           |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |    X                                      X                               |         2|
  LYMPHOMA MALIGNANT                        |                                        X                                  |         2|
THYMUS                                      | +  M  M  +  M  +  +  M  +  M  M  M  M  +  +  +  M  +  +  +  +  M  +       | 30       |
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M  M  M  M  M  M  M  M  +  M  M  M  M  M  M  M  M  M  M  M       |  2       |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +       | 47       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                        X                          X       |         5|
  CARCINOMA,METASTATIC,HARDERIAN GLAND      |             X                                                             |         1|
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |    X                                                                      |         1|
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   66
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:57.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 8| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 2| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|         S      M|
                                            | 7| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 8| 8| 4| 4| 4| 4| 4| 5| 5| 5| 5|         U      O|
100MG/KGR 2YR 13    13                      | 8| 6| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 0| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ADENOMA                                   | X                             X                                           |         4|
  CARCINOMA                                 |             X                                                             |         1|
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   67
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:58.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 3| 3| 3| 5| 5| 5| 3| 3| 3| 5| 5| 5|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3|                                          S      M|
                                            | 2| 2| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4|                                          U      O|
CONTROL R 64W 14    14                      | 2| 3| 4| 6| 7| 8| 3| 4| 5| 7| 8| 9|                                          E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +                                        | 12       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   68
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:58.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 3| 3| 3| 5| 5| 5| 3| 3| 3| 5| 5| 5|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3|                                          S      M|
                                            | 2| 2| 2| 4| 5| 5| 2| 2| 2| 5| 5| 5|                                          U      O|
25 MG/KGR 64W 15    15                      | 5| 6| 7| 9| 0| 1| 6| 7| 8| 0| 1| 2|                                          E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +                                        | 12       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   69
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:58.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 3| 3| 3| 5| 5| 5| 3| 3| 3| 5| 5| 5|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3|                                          S      M|
                                            | 2| 2| 3| 5| 5| 5| 2| 3| 3| 5| 5| 5|                                          U      O|
50 MG/KGR 64W 16    16                      | 8| 9| 0| 2| 3| 4| 9| 0| 1| 3| 4| 5|                                          E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +                                        | 12       |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

SKIN                                        |                                  +                                        |  1       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211701                                                                                      PAGE:   70
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/15/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 14:24:58.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 3| 3| 3| 5| 5| 5| 3| 3| 3| 5| 5| 5|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                          S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3|                                          S      M|
                                            | 3| 3| 3| 5| 5| 5| 3| 3| 3| 5| 5| 5|                                          U      O|
100MG/KGR 64W 17    17                      | 1| 2| 3| 5| 6| 7| 2| 3| 4| 6| 7| 8|                                          E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +                                        | 12       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED