NCTR Study 211701 Pathology Tables
NCTR EXP/TEST: 211701 PAGE: 1
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:10.6
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DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 1| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 8|
| 0| 3| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 8|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3| S R R|
| 5| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 5| 5| 6| 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 6| U V I|
CONTROL A 2YR 1 1 | 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| 8| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
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ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 3 | |
GALLBLADDER | M + + + + + + + + + + + + + + + + + + + + + + + M | |
AUTOLYSIS | 4 | |
CRYSTALS,EPITHELIUM | | |
INTESTINE LARGE | A M + + + + + + + + + + + + + + + + + + + + + + A | |
INTESTINE LARGE,CECUM | A M + + + + + + + + + + + + + + + + + + + + + + A | |
INTESTINE LARGE,COLON | A M + + + + + + + + + + + + + + + + + + + + + + A | |
INTESTINE LARGE,RECTUM | A M + + + + + + + + + + + + + + + + + + + + + + A | |
GRANULOMA | | |
INTESTINE SMALL | A M + + + + + + + + + + + + + + + + + + + + + + A | |
INTESTINE SMALL,DUODENUM | A M + + + + + + + + + + + + + + + + + + + + + + A | |
INTESTINE SMALL,ILEUM | A M + + + + + + + + + + + + + + + + + + + + + + A | |
INTESTINE SMALL,JEJUNUM | A M + + + + + + + + + + + + + + + + + + + + + + A | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 4 3| |
BASOPHILIC FOCUS | X | |
CLEAR CELL FOCUS | | |
CLEAR CELL FOCUS,THREE | X | |
GRANULOMA,MULTIPLE | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1 | |
NECROSIS,HEPATOCYTE | 4| |
NECROSIS,MULTIFOCAL,HEPATOCYTE | | |
VACUOLIZATION CYTOPLASMIC,CENTRILOBULAR | 2 | |
PANCREAS | + A + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 4| |
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 4 | |
DEGENERATION | 3 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 3 3 | |
STOMACH | + M + + + + + + + + + + + + + + + + + + + + + + A | |
STOMACH,FORESTOMACH | + M + + + + + + + + + + + + + + + + + + + + + + A | |
AUTOLYSIS | | |
HYPERKERATOSIS,FOCAL | | |
HYPERPLASIA,SQUAMOUS | | |
STOMACH,GLANDULAR | + M + + + + + + + + + + + + + + + + + + + + + + A | |
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+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 2
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:10.8
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DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 1| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 8|
| 0| 3| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 8|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3| S R R|
| 5| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 5| 5| 6| 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 6| U V I|
CONTROL A 2YR 1 1 | 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| 8| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
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ALIMENTARY SYSTEM
AUTOLYSIS | 3 | |
INFLAMMATION,ACUTE,SUBMUCOSA | | |
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 3 | |
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CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS,AORTA | 3 4 | |
HEART | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 4 | |
CARDIOMYOPATHY | 1 | |
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ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + + + + + M + + + + + + M | |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + + + + + M + + + + + + M | |
AUTOLYSIS | 3 4 | |
CYST,UNILATERAL | X | |
CYTOLOGIC ALTERATIONS | | |
CYTOPLASMIC ALTERATION | 3 | |
HYPERPLASIA | 2 3 | |
HYPERPLASIA,SPINDLE CELL | 3 3 3 2 3 3 2 2 3 | |
HYPERTROPHY | | |
ADRENAL GLAND,MEDULLA | + + + + + + + + + + + + + + + + + M + + + + + + M | |
AUTOLYSIS | 3 4 | |
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
PARATHYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 3 | |
CYST | | |
PITUITARY GLAND | + M M + + + + + + + M + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 | |
CYST | X X | |
HYPERPLASIA,FOCAL,PARS DISTALIS | | |
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 3 | |
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+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 3
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:11.0
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DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 1| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 8|
| 0| 3| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 8|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3| S R R|
| 5| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 5| 5| 6| 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 6| U V I|
CONTROL A 2YR 1 1 | 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| 8| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
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ENDOCRINE SYSTEM
CYST,FOLLICLE | X X X | |
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GENITAL SYSTEM
COAGULATING GLAND | + A + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 | |
EPIDIDYMIS | + A + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 | |
GRANULOMA SPERM | 3 | |
INFLAMMATION,CHRONIC | | |
PREPUTIAL GLAND | + A + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 2 4 2 3 4| |
AUTOLYSIS | 3 | |
CYST | | |
DILATATION | 2 | |
INFLAMMATION | 4 | |
INFLAMMATION,CHRONIC,UNILATERAL | | |
PROSTATE | A + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 | |
AUTOLYSIS | 4 | |
SEMINAL VESICLE | + A + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 2| |
AUTOLYSIS | 3 | |
DILATATION | 2 | |
TESTES | + A + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY,UNILATERAL | | |
AUTOLYSIS | 3 3| |
DEGENERATION,BILATERAL | 2 | |
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HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 4 3| |
HYPERPLASIA | | |
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
GRANULOMA,INGUINAL | X | |
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+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 4
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:11.2
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DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 1| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 8|
| 0| 3| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 8|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3| S R R|
| 5| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 5| 5| 6| 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 6| U V I|
CONTROL A 2YR 1 1 | 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| 8| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
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HEMATOPOIETIC SYSTEM
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 | |
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 4 3| |
DEGENERATION | 3 | |
HEMATOPOIETIC CELL PROLIFERATION | | |
HEMORRHAGE | 2 | |
HYPERPLASIA | 3 | |
SPLEEN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 4 3| |
HEMATOPOIETIC CELL PROLIFERATION | 4| |
HYPERPLASIA,LYMPHOID | 4 2 | |
THYMUS | + + + + + + M + + + M + + M M + + + M M + + M M M | |
AUTOLYSIS | 3 4 | |
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INTEGUMENTARY SYSTEM
MAMMARY GLAND | + + M M M M M + + M + M M M M M M M M M M M M M M | |
AUTOLYSIS | 3 4 | |
SKIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 4 | |
GRANULOMA | X | |
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MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + M + | |
AUTOLYSIS | 3 4 | |
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 4 | |
FIBROUS OSTEODYSTROPHY | 3 | |
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 3 | |
MINERALIZATION,FOCAL | 2 | |
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+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 5
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:11.4
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DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 1| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 8|
| 0| 3| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 8|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3| S R R|
| 5| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 5| 5| 6| 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 6| U V I|
CONTROL A 2YR 1 1 | 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| 8| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
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NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 4 | |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 4 | |
MINERALIZATION,THALAMUS | 3 2 2 1 2 2 2 2 3 2 2 | |
PERIPHERAL NERVE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 3 | |
DEGENERATION | | |
DEMYELINATION | 3 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 | |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 4 | |
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RESPIRATORY SYSTEM
LARYNX | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 3 | |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 4 | |
DILATATION,BRONCHIOLE,GLANDS | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 | |
NOSE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 4 | |
TRACHEA | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 3 | |
DILATATION,GLANDS | 2 | |
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SPECIAL SENSES SYSTEM
EYE | A + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 | |
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY,FOCAL,UNILATERAL | 2 | |
AUTOLYSIS | 3 3 | |
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+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 6
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:11.5
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DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 1| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 8|
| 0| 3| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 8|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3| S R R|
| 5| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 5| 5| 6| 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 6| U V I|
CONTROL A 2YR 1 1 | 8| 9| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7| 8| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
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SPECIAL SENSES SYSTEM
HYPERPLASIA,FOCAL,UNILATERAL | | |
HYPERPLASIA,UNILATERAL | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 3 2 2 | |
LACRIMAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY,FOCAL | | |
AUTOLYSIS | 3 4 | |
ZYMBAL'S GLAND | + M + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | | |
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URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 4 3| |
CYST,RENAL TUBULE | X X X X | |
DEGENERATION,RENAL TUBULE | 2 2 2 2 2 | |
GLOMERULOSCLEROSIS | 2| |
INFARCT,UNILATERAL | 2 | |
INFLAMMATION,CHRONIC | 1 | |
MINERALIZATION,RENAL TUBULE | 2 1 2 1 | |
NEPHROPATHY | | |
REGENERATION,RENAL TUBULE | 1 2 1 2 2 2 2 2 2 2 2 | |
VACUOLIZATION CYTOPLASMIC,BILATERAL,RENAL | 3 | |
TUBULE | | |
URINARY BLADDER | A + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 4 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 7
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:26.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 0| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 8| 7| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| S R R|
| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 5| 6| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| U V I|
CONTROL A 2YR 1 1 | 0| 1| 9| 1| 2| 3| 4| 5| 6| 7| 8| 5| 8| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 4 2 | 4 3.0|
GALLBLADDER | A A M + + + + + + + + + + + + + + + + + + + + | 43 |
AUTOLYSIS | 3 | 2 3.5|
CRYSTALS,EPITHELIUM | 3 | 1 3.0|
INTESTINE LARGE | A A A + + + + + + + + + A + + + + + + + + + + | 41 |
INTESTINE LARGE,CECUM | A A A + + + + + + + + + A + + + + + + + + + + | 41 |
INTESTINE LARGE,COLON | A A A + + + + + + + + + A + + + + + + + + + + | 41 |
INTESTINE LARGE,RECTUM | A A A + + + + + + + + + A + + + + + + + + + + | 41 |
GRANULOMA | X | 1 |
INTESTINE SMALL | A A A + + + + + + + + + + + + + + + + + + + + | 42 |
INTESTINE SMALL,DUODENUM | A A A + + + + + + + + + A + + + + + + + + + + | 41 |
INTESTINE SMALL,ILEUM | A A A + + + + + + + + + + + + + + + + + + + + | 42 |
INTESTINE SMALL,JEJUNUM | A A A + + + + + + + + + + + + + + + + + + + + | 42 |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | 4 | 3 3.6|
BASOPHILIC FOCUS | X X | 3 |
CLEAR CELL FOCUS | X | 1 |
CLEAR CELL FOCUS,THREE | | 1 |
GRANULOMA,MULTIPLE | X | 1 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 2 1.0|
NECROSIS,HEPATOCYTE | | 1 4.0|
NECROSIS,MULTIFOCAL,HEPATOCYTE | 2 | 1 2.0|
VACUOLIZATION CYTOPLASMIC,CENTRILOBULAR | 3 | 2 2.5|
PANCREAS | + A + + + + + + + + + + + + + + + + + + + + + | 46 |
AUTOLYSIS | 4 4 | 4 3.7|
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | 4 4 3 | 5 3.6|
DEGENERATION | | 1 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 3 2 2 3 3 | 9 2.6|
STOMACH | A A A + + + + + + + + + + + + + + + + + + + + | 43 |
STOMACH,FORESTOMACH | A A A + + + + + + + + + + + + + + + + + + + + | 43 |
AUTOLYSIS | 4 | 1 4.0|
HYPERKERATOSIS,FOCAL | 2 | 1 2.0|
HYPERPLASIA,SQUAMOUS | 2 | 1 2.0|
STOMACH,GLANDULAR | A A A + + + + + + + + + + + + + + + + + + + + | 43 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 8
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:27.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 0| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 8| 7| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| S R R|
| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 5| 6| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| U V I|
CONTROL A 2YR 1 1 | 0| 1| 9| 1| 2| 3| 4| 5| 6| 7| 8| 5| 8| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
AUTOLYSIS | 4 | 2 3.5|
INFLAMMATION,ACUTE,SUBMUCOSA | 3 | 1 3.0|
TONGUE | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 4 2 | 4 3.0|
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS,AORTA | 3 | 3 3.3|
HEART | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | 3 | 3 3.3|
CARDIOMYOPATHY | | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + A + + + + + + + + + + + + + + + + + + + + + | 45 |
ADRENAL GLAND,CORTEX | + A + + + + + + + + + + + + + + + + + + + + + | 45 |
AUTOLYSIS | 4 2 | 4 3.2|
CYST,UNILATERAL | | 1 |
CYTOLOGIC ALTERATIONS | 1 | 1 1.0|
CYTOPLASMIC ALTERATION | 2 2 1 | 4 2.0|
HYPERPLASIA | 2 3 3 3 | 6 2.6|
HYPERPLASIA,SPINDLE CELL | 3 3 3 3 2 2 2 2 2 3 2 2 2 2 2 | 24 2.4|
HYPERTROPHY | 2 2 | 2 2.0|
ADRENAL GLAND,MEDULLA | + A + + + + + + + + + + + + + + + + + + + + + | 45 |
AUTOLYSIS | 2 | 3 3.0|
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
PARATHYROID GLAND | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 4 2 | 4 3.0|
CYST | X | 1 |
PITUITARY GLAND | + A + + + + + + + + + + M + + + + + M + + + + | 42 |
AUTOLYSIS | 4 2 | 3 3.0|
CYST | | 2 |
HYPERPLASIA,FOCAL,PARS DISTALIS | 3 | 1 3.0|
THYROID GLAND | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 4 2 | 4 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 9
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:27.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 0| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 8| 7| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| S R R|
| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 5| 6| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| U V I|
CONTROL A 2YR 1 1 | 0| 1| 9| 1| 2| 3| 4| 5| 6| 7| 8| 5| 8| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
CYST,FOLLICLE | X X | 5 |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + A + + + + + + + + + + + + + + + + + + + + + | 46 |
AUTOLYSIS | 4 2 | 3 3.0|
EPIDIDYMIS | + A + + + + + + + + + + + + + + + + + + + + + | 46 |
AUTOLYSIS | 4 2 | 3 3.0|
GRANULOMA SPERM | | 1 3.0|
INFLAMMATION,CHRONIC | 1 | 1 1.0|
PREPUTIAL GLAND | + A + + + + + + + + + + + + + + + + + + + + + | 46 |
ATROPHY | 2 3 2 2 2 3 3 2 2 | 15 2.6|
AUTOLYSIS | 4 2 | 3 3.0|
CYST | X | 1 |
DILATATION | | 1 2.0|
INFLAMMATION | | 1 4.0|
INFLAMMATION,CHRONIC,UNILATERAL | 3 | 1 3.0|
PROSTATE | + A + + + + + + + + + + + + + + + + + + + + + | 46 |
ATROPHY | 2 | 2 2.5|
AUTOLYSIS | 4 2 | 3 3.3|
SEMINAL VESICLE | + A + + + + + + + + + + + + + + + + + + + + + | 46 |
ATROPHY | | 1 2.0|
AUTOLYSIS | 4 2 | 3 3.0|
DILATATION | | 1 2.0|
TESTES | A A + + + + + + + + + + + + + + + + + + + + + | 45 |
ATROPHY,UNILATERAL | 3 | 1 3.0|
AUTOLYSIS | 2 | 3 2.6|
DEGENERATION,BILATERAL | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | | 3 3.3|
HYPERPLASIA | 3 | 1 3.0|
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
GRANULOMA,INGUINAL | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 10
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:27.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 0| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 8| 7| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| S R R|
| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 5| 6| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| U V I|
CONTROL A 2YR 1 1 | 0| 1| 9| 1| 2| 3| 4| 5| 6| 7| 8| 5| 8| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | 4 4 3 | 4 3.5|
LYMPH NODE,MESENTERIC | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 4 2 | 5 3.2|
DEGENERATION | 2 3 1 | 4 2.2|
HEMATOPOIETIC CELL PROLIFERATION | 3 | 1 3.0|
HEMORRHAGE | | 1 2.0|
HYPERPLASIA | | 1 3.0|
SPLEEN | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 4 | 4 3.5|
HEMATOPOIETIC CELL PROLIFERATION | 3 | 2 3.5|
HYPERPLASIA,LYMPHOID | 3 | 3 3.0|
THYMUS | + M M + + + + M + + + + M + + M + M M M M M + | 29 |
AUTOLYSIS | 3 | 3 3.3|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M M M M M M M M M M M M M M M M M M M M M M M | 5 |
AUTOLYSIS | | 2 3.5|
SKIN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | 4 4 | 4 3.7|
GRANULOMA | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
BONE,FEMUR | + A + + + + + + + + + + + + + + + + + + + + + | 46 |
AUTOLYSIS | 2 | 3 3.0|
BONE,STERNUM | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 2 | 3 3.0|
FIBROUS OSTEODYSTROPHY | 2 2 1 | 4 2.0|
SKELETAL MUSCLE | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 4 2 | 4 3.0|
MINERALIZATION,FOCAL | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 11
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:27.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 0| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 8| 7| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| S R R|
| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 5| 6| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| U V I|
CONTROL A 2YR 1 1 | 0| 1| 9| 1| 2| 3| 4| 5| 6| 7| 8| 5| 8| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
BRAIN | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
BRAIN,CEREBELLUM | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 4 4 | 4 3.7|
BRAIN,CEREBRUM | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 4 4 | 4 3.7|
MINERALIZATION,THALAMUS | 3 1 2 2 2 2 2 2 2 2 2 2 2 2 | 25 2.0|
PERIPHERAL NERVE | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 4 2 | 4 3.0|
DEGENERATION | 3 1 | 2 2.0|
DEMYELINATION | | 1 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 3.0|
SPINAL CORD | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 4 4 | 4 3.7|
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + A + + + + + + M + + + + + + + + + + + + + + | 46 |
AUTOLYSIS | 4 2 | 4 3.0|
LUNG | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | 3 | 3 3.3|
DILATATION,BRONCHIOLE,GLANDS | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 2 1 | 4 2.2|
NOSE | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 4 2 | 4 3.2|
TRACHEA | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 4 2 | 4 3.0|
DILATATION,GLANDS | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + A + + + + + + + + + + + + + + + + + + + + + | 46 |
AUTOLYSIS | 4 2 | 3 3.0|
HARDERIAN GLAND | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
ATROPHY,FOCAL,UNILATERAL | | 1 2.0|
AUTOLYSIS | 4 2 | 4 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 12
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:27.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 0| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 8| 7| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| S R R|
| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 5| 6| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| U V I|
CONTROL A 2YR 1 1 | 0| 1| 9| 1| 2| 3| 4| 5| 6| 7| 8| 5| 8| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
HYPERPLASIA,FOCAL,UNILATERAL | 2 | 1 2.0|
HYPERPLASIA,UNILATERAL | | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 5 2.0|
LACRIMAL GLAND | + + + + + + + + + + + + + + + + + + + + + + M | 47 |
ATROPHY,FOCAL | 1 | 1 1.0|
AUTOLYSIS | 4 4 3 | 5 3.6|
ZYMBAL'S GLAND | + A + + + + + + + M + + + + + + + + + + + + + | 45 |
AUTOLYSIS | 4 2 | 2 3.0|
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + A A + + + + + + + + + + + + + + + + + + + + | 46 |
AUTOLYSIS | 4 3 | 5 3.4|
CYST,RENAL TUBULE | X | 5 |
DEGENERATION,RENAL TUBULE | | 5 2.0|
GLOMERULOSCLEROSIS | 2 | 2 2.0|
INFARCT,UNILATERAL | 2 | 2 2.0|
INFLAMMATION,CHRONIC | | 1 1.0|
MINERALIZATION,RENAL TUBULE | | 4 1.5|
NEPHROPATHY | 2 2 2 2 3 2 | 6 2.1|
REGENERATION,RENAL TUBULE | | 11 1.8|
VACUOLIZATION CYTOPLASMIC,BILATERAL,RENAL | | 1 3.0|
TUBULE | | |
URINARY BLADDER | + A + + + + + + + + + + + + + + + + + + + + + | 46 |
AUTOLYSIS | 4 2 | 3 3.3|
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 2 2 | 4 2.5|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 13
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:31.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 3| 5| 7| 3| 2| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 8| 3| 6| 5| 4| 8| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 5|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3| S R R|
| 6| 6| 6| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| 5| 6| 6| 8| 9| 9| 9| 9| 9| 9| 6| U V I|
25 MG/KGA 2YR 2 2 | 4| 6| 8| 4| 5| 6| 1| 2| 3| 4| 5| 6| 7| 8| 3| 7| 8| 9| 0| 1| 2| 3| 4| 5| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + | |
GALLBLADDER | + + + + + + + | |
AUTOLYSIS | 3 4 4 4 | |
INTESTINE LARGE | + + A A A A A | |
INTESTINE LARGE,CECUM | + + A A A A A | |
INTESTINE LARGE,COLON | + + A A A A A | |
INTESTINE LARGE,RECTUM | + + A A A A A | |
INTESTINE SMALL | + + A A + A + A | |
INTESTINE SMALL,DUODENUM | + + A A + A + A | |
AUTOLYSIS | 3 | |
INTESTINE SMALL,ILEUM | + + A A A A A | |
INTESTINE SMALL,JEJUNUM | + + A A A A A | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 3 | |
BASOPHILIC FOCUS | X | |
CLEAR CELL FOCUS | | |
EOSINOPHILIC FOCUS | | |
FATTY CHANGE,FOCAL | | |
HYPERPLASIA,BILE DUCT | 2 | |
INFARCT | X X | |
MIXED CELL FOCUS | X | |
NECROSIS,HEPATOCYTE | 3| |
REGENERATION,FOCAL | 3 | |
VACUOLIZATION CYTOPLASMIC,CENTRILOBULAR | 1 | |
PANCREAS | + + + + + + + | |
ATROPHY,ACINAR CELL | | |
CYST,DUCT | | |
FIBROSIS | | |
SALIVARY GLANDS | + + A + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
STOMACH | + + + + + + + | |
STOMACH,FORESTOMACH | + + + + + + + | |
STOMACH,GLANDULAR | + + + + + + + | |
AUTOLYSIS | 4 4 4 2| |
TONGUE | + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 14
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:31.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 3| 5| 7| 3| 2| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 8| 3| 6| 5| 4| 8| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 5|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3| S R R|
| 6| 6| 6| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| 5| 6| 6| 8| 9| 9| 9| 9| 9| 9| 6| U V I|
25 MG/KGA 2YR 2 2 | 4| 6| 8| 4| 5| 6| 1| 2| 3| 4| 5| 6| 7| 8| 3| 7| 8| 9| 0| 1| 2| 3| 4| 5| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + | |
HEART | + + + + + + + | |
HEMORRHAGE,MYOCARDIUM | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + | |
ADRENAL GLAND,CORTEX | + + + + + + + | |
AUTOLYSIS | 3 | |
CYTOPLASMIC ALTERATION | | |
HYPERPLASIA,SPINDLE CELL | 1 1 2 2 3 | |
ADRENAL GLAND,MEDULLA | + + + + + + + | |
ISLETS, PANCREATIC | + + + + + + + | |
PARATHYROID GLAND | + + M M + M + | |
PITUITARY GLAND | M + + + + + + | |
AUTOLYSIS | 4 | |
THYROID GLAND | + + + + + + + | |
CYST,FOLLICLE | | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + + + + + + + | |
AUTOLYSIS | 4 | |
EPIDIDYMIS | + + + + + + + | |
AUTOLYSIS | 4 | |
PREPUTIAL GLAND | + + M + + + + | |
ABSCESS | | |
ATROPHY | 3 3 | |
ECTASIA,DUCT | 3 3 | |
PROSTATE | + + + + + + + | |
SEMINAL VESICLE | + + + + + + + | |
AUTOLYSIS | 4 | |
DISTENDED | | |
TESTES | + + + + + + + | |
AUTOLYSIS | 4 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 15
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:31.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 3| 5| 7| 3| 2| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 8| 3| 6| 5| 4| 8| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 5|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3| S R R|
| 6| 6| 6| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| 5| 6| 6| 8| 9| 9| 9| 9| 9| 9| 6| U V I|
25 MG/KGA 2YR 2 2 | 4| 6| 8| 4| 5| 6| 1| 2| 3| 4| 5| 6| 7| 8| 3| 7| 8| 9| 0| 1| 2| 3| 4| 5| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + | |
HYPERPLASIA | 2 | |
LYMPH NODE | + + + + + + + + + + + | |
LYMPH NODE,MANDIBULAR | + + A + + + + | |
INFLAMMATION,CHRONIC | | |
LYMPH NODE,MESENTERIC | + + + + + + + + + + | |
DEGENERATION | 2 3 2 2 | |
SPLEEN | + + + + + + + + + + + + + | |
APOPTOSIS,LYMPHOCYTE | 3| |
ATROPHY,LYMPHOCYTE | 3 2 | |
CONGESTION | 4 | |
HEMATOPOIETIC CELL PROLIFERATION | 3 3 3 3 3| |
THYMUS | + M M + + M + M | |
ECTOPIC PARATHYROID GLAND | | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M M M M M M M | |
SKIN | + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + | |
BONE,FEMUR | + + + + + + + | |
BONE,STERNUM | + + + + + + + | |
SKELETAL MUSCLE | + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + | |
AUTOLYSIS | 3 | |
BRAIN,CEREBRUM | + + + + + + + | |
AUTOLYSIS | 3 | |
MINERALIZATION,THALAMUS | 2 2 | |
PERIPHERAL NERVE | + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 16
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:31.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 3| 5| 7| 3| 2| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 8| 3| 6| 5| 4| 8| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 5|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 3| S R R|
| 6| 6| 6| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9| 5| 6| 6| 8| 9| 9| 9| 9| 9| 9| 6| U V I|
25 MG/KGA 2YR 2 2 | 4| 6| 8| 4| 5| 6| 1| 2| 3| 4| 5| 6| 7| 8| 3| 7| 8| 9| 0| 1| 2| 3| 4| 5| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
SPINAL CORD | + + + + + + + | |
AUTOLYSIS | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + + + + | |
LUNG | + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
INFLAMMATION,CHRONIC ACTIVE | 3 | |
NOSE | + + + + + + + | |
TRACHEA | + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + | |
CATARACT,LENS | X | |
HARDERIAN GLAND | + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
LACRIMAL GLAND | + + A + + + + | |
ZYMBAL'S GLAND | + + + + + M + | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + | |
ACCUMULATION HYALINE DROPLET,RENAL TUBULE | | |
AUTOLYSIS | 3 | |
GLOMERULOSCLEROSIS | 2 3 | |
INFARCT,UNILATERAL | 2 | |
MINERALIZATION,RENAL TUBULE | 1 | |
URINARY BLADDER | + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 17
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:33.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 8| 2| 1| 2| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 4| 7| 2| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| S R R|
| 6| 7| 7| 7| 8| 9| 9| 9| 9| 9| 9| 9| 9| 5| 5| 6| 9| 9| 9| 9| 9| 9| 9| U V I|
25 MG/KGA 2YR 2 2 | 9| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 7| 6| 7| 9| 2| 3| 4| 5| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + | 11 |
GALLBLADDER | + + + M | 10 |
AUTOLYSIS | | 4 3.7|
INTESTINE LARGE | + + + A | 5 |
INTESTINE LARGE,CECUM | + + + A | 5 |
INTESTINE LARGE,COLON | + + + A | 5 |
INTESTINE LARGE,RECTUM | + + + A | 5 |
INTESTINE SMALL | + + + A | 7 |
INTESTINE SMALL,DUODENUM | + + + A | 7 |
AUTOLYSIS | | 1 3.0|
INTESTINE SMALL,ILEUM | + + + A | 5 |
INTESTINE SMALL,JEJUNUM | + + + A | 5 |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 2 3.0|
BASOPHILIC FOCUS | X X | 3 |
CLEAR CELL FOCUS | X | 1 |
EOSINOPHILIC FOCUS | X | 1 |
FATTY CHANGE,FOCAL | 3 | 1 3.0|
HYPERPLASIA,BILE DUCT | | 1 2.0|
INFARCT | | 2 |
MIXED CELL FOCUS | | 1 |
NECROSIS,HEPATOCYTE | | 1 3.0|
REGENERATION,FOCAL | | 1 3.0|
VACUOLIZATION CYTOPLASMIC,CENTRILOBULAR | | 1 1.0|
PANCREAS | + + + M | 10 |
ATROPHY,ACINAR CELL | 4 | 1 4.0|
CYST,DUCT | X | 1 |
FIBROSIS | 4 | 1 4.0|
SALIVARY GLANDS | + + + + | 10 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 2 | 2 2.0|
STOMACH | + + + A | 10 |
STOMACH,FORESTOMACH | + + + A | 10 |
STOMACH,GLANDULAR | + + + A | 10 |
AUTOLYSIS | | 4 3.5|
TONGUE | + + + A | 10 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 18
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:33.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 8| 2| 1| 2| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 4| 7| 2| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| S R R|
| 6| 7| 7| 7| 8| 9| 9| 9| 9| 9| 9| 9| 9| 5| 5| 6| 9| 9| 9| 9| 9| 9| 9| U V I|
25 MG/KGA 2YR 2 2 | 9| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 7| 6| 7| 9| 2| 3| 4| 5| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + | 11 |
HEART | + + + + | 11 |
HEMORRHAGE,MYOCARDIUM | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + | 11 |
ADRENAL GLAND,CORTEX | + + + + | 11 |
AUTOLYSIS | 3 | 2 3.0|
CYTOPLASMIC ALTERATION | 2 3 | 2 2.5|
HYPERPLASIA,SPINDLE CELL | 1 2 | 7 1.7|
ADRENAL GLAND,MEDULLA | + + + + | 11 |
ISLETS, PANCREATIC | + + + M | 10 |
PARATHYROID GLAND | + + M M | 6 |
PITUITARY GLAND | + + + + | 10 |
AUTOLYSIS | 3 | 2 3.5|
THYROID GLAND | + + + + | 11 |
CYST,FOLLICLE | X | 1 |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + + + A | 10 |
AUTOLYSIS | | 1 4.0|
EPIDIDYMIS | + + + A | 10 |
AUTOLYSIS | | 1 4.0|
PREPUTIAL GLAND | + + + A + | 10 |
ABSCESS | X | 1 |
ATROPHY | 2 2 | 4 2.5|
ECTASIA,DUCT | | 2 3.0|
PROSTATE | + + + A | 10 |
SEMINAL VESICLE | + + + A + | 11 |
AUTOLYSIS | | 1 4.0|
DISTENDED | 3 | 1 3.0|
TESTES | + + + + | 11 |
AUTOLYSIS | | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 19
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:33.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 8| 2| 1| 2| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 4| 7| 2| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| S R R|
| 6| 7| 7| 7| 8| 9| 9| 9| 9| 9| 9| 9| 9| 5| 5| 6| 9| 9| 9| 9| 9| 9| 9| U V I|
25 MG/KGA 2YR 2 2 | 9| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 7| 6| 7| 9| 2| 3| 4| 5| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + A | 10 |
HYPERPLASIA | 3 | 2 2.5|
LYMPH NODE | + + + + | 15 |
LYMPH NODE,MANDIBULAR | + + + + | 10 |
INFLAMMATION,CHRONIC | 2 | 1 2.0|
LYMPH NODE,MESENTERIC | + + + A | 13 |
DEGENERATION | | 4 2.2|
SPLEEN | + + + A | 16 |
APOPTOSIS,LYMPHOCYTE | | 1 3.0|
ATROPHY,LYMPHOCYTE | 3 | 3 2.6|
CONGESTION | | 1 4.0|
HEMATOPOIETIC CELL PROLIFERATION | 2 3 | 7 2.8|
THYMUS | M M + M + | 6 |
ECTOPIC PARATHYROID GLAND | X | 1 |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M M M M | 0 |
SKIN | + + + A | 10 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + | 11 |
BONE,FEMUR | + + + + | 11 |
BONE,STERNUM | + + + + | 11 |
SKELETAL MUSCLE | + + + A | 10 |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + A | 10 |
BRAIN,CEREBELLUM | + + + A | 10 |
AUTOLYSIS | | 1 3.0|
BRAIN,CEREBRUM | + + + A | 10 |
AUTOLYSIS | | 1 3.0|
MINERALIZATION,THALAMUS | | 2 2.0|
PERIPHERAL NERVE | + + + A | 10 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 20
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:33.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 8| 2| 1| 2| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 4| 7| 2| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| S R R|
| 6| 7| 7| 7| 8| 9| 9| 9| 9| 9| 9| 9| 9| 5| 5| 6| 9| 9| 9| 9| 9| 9| 9| U V I|
25 MG/KGA 2YR 2 2 | 9| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 7| 6| 7| 9| 2| 3| 4| 5| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
SPINAL CORD | + + + A | 10 |
AUTOLYSIS | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + | 11 |
LUNG | + + + + + + + + + + | 20 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 2.0|
INFLAMMATION,CHRONIC ACTIVE | | 1 3.0|
NOSE | + + + + | 11 |
TRACHEA | + + + A | 10 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + A | 11 |
CATARACT,LENS | | 1 |
HARDERIAN GLAND | + + + A + + | 16 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 2.0|
LACRIMAL GLAND | + + + + | 10 |
ZYMBAL'S GLAND | + + + A | 9 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + A | 10 |
ACCUMULATION HYALINE DROPLET,RENAL TUBULE | 3 4 | 2 3.5|
AUTOLYSIS | | 1 3.0|
GLOMERULOSCLEROSIS | 2 3 | 4 2.5|
INFARCT,UNILATERAL | | 1 2.0|
MINERALIZATION,RENAL TUBULE | | 1 1.0|
URINARY BLADDER | + + + A | 10 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 21
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:37.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 5| 5| 8| 2| 2| 4| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 2| 2| 1| 8| 9| 7| 5| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 3| S R R|
| 0| 6| 6| 7| 7| 7| 8| 9| 0| 0| 0| 0| 0| 0| 5| 6| 9| 9| 9| 9| 0| 0| 0| 0| 6| U V I|
50 MG/KGA 2YR 3 3 | 5| 5| 9| 2| 3| 8| 1| 9| 0| 1| 2| 3| 4| 5| 4| 9| 6| 7| 8| 9| 0| 1| 2| 3| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + | |
AUTOLYSIS | | |
GALLBLADDER | + + + + + + + + | |
AUTOLYSIS | 4 4 4 4 4 4| |
CYST | X | |
INTESTINE LARGE | + A A A A A + A | |
INTESTINE LARGE,CECUM | + A A A A A + A | |
INTESTINE LARGE,COLON | + A A A A A + A | |
INTESTINE LARGE,RECTUM | + A A A A A + A | |
INTESTINE SMALL | + A A A A A + + A | |
INTESTINE SMALL,DUODENUM | + A A A A A + A | |
INTESTINE SMALL,ILEUM | + A A A A A + + A | |
INTESTINE SMALL,JEJUNUM | + A A A A A + A | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BASOPHILIC FOCUS | | |
CLEAR CELL FOCUS | X | |
CLEAR CELL FOCUS,MULTIPLE | X | |
CLEAR CELL FOCUS,TWO | | |
CONGESTION | 4 | |
EOSINOPHILIC FOCUS | | |
FIBROSIS,FOCAL | | |
GRANULOMA,MULTIPLE | X | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
NECROSIS,FOCAL,HEPATOCYTE | | |
VACUOLIZATION CYTOPLASMIC,CENTRILOBULAR | 1 | |
MESENTERY | + | |
PANCREAS | + + M + + + + + | |
AUTOLYSIS | 3 4 | |
SALIVARY GLANDS | + + + A + + + + | |
STOMACH | + + + + + + + + | |
STOMACH,FORESTOMACH | + + + + + + + + | |
AUTOLYSIS | 4 | |
STOMACH,GLANDULAR | + + + + + + + + | |
AUTOLYSIS | 4 4 4 4 3| |
TONGUE | + + + + + + + + | |
AUTOLYSIS | | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 22
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:38.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 5| 5| 8| 2| 2| 4| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 2| 2| 1| 8| 9| 7| 5| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 3| S R R|
| 0| 6| 6| 7| 7| 7| 8| 9| 0| 0| 0| 0| 0| 0| 5| 6| 9| 9| 9| 9| 0| 0| 0| 0| 6| U V I|
50 MG/KGA 2YR 3 3 | 5| 5| 9| 2| 3| 8| 1| 9| 0| 1| 2| 3| 4| 5| 4| 9| 6| 7| 8| 9| 0| 1| 2| 3| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + | |
HEART | + + + + + + + + | |
AUTOLYSIS | 3 | |
CONGESTION | 4 | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + | |
ADRENAL GLAND,CORTEX | + + + + + + + + | |
AUTOLYSIS | 3 | |
HYPERPLASIA | | |
HYPERPLASIA,SPINDLE CELL | 2 | |
ADRENAL GLAND,MEDULLA | + + + + + + + + | |
AUTOLYSIS | 3 | |
ISLETS, PANCREATIC | + + M + + + + + | |
PARATHYROID GLAND | M M M + + + M + | |
AUTOLYSIS | | |
PITUITARY GLAND | + + + + + M M + | |
AUTOLYSIS | | |
THYROID GLAND | + + + + + + M + | |
AUTOLYSIS | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + + M A + + + + + | |
AUTOLYSIS | | |
DISTENDED | 3 | |
INFLAMMATION,CHRONIC ACTIVE | 3 | |
EPIDIDYMIS | + + + A + + + + + | |
AUTOLYSIS | | |
INFLAMMATION,CHRONIC ACTIVE | 3 | |
PREPUTIAL GLAND | + + + M + + + + + + | |
ATROPHY | 4 4 3 4 4 3| |
AUTOLYSIS | | |
CYST | X | |
ECTASIA,DUCT | 4 4 4 3 3 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 23
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:38.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 5| 5| 8| 2| 2| 4| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 2| 2| 1| 8| 9| 7| 5| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 3| S R R|
| 0| 6| 6| 7| 7| 7| 8| 9| 0| 0| 0| 0| 0| 0| 5| 6| 9| 9| 9| 9| 0| 0| 0| 0| 6| U V I|
50 MG/KGA 2YR 3 3 | 5| 5| 9| 2| 3| 8| 1| 9| 0| 1| 2| 3| 4| 5| 4| 9| 6| 7| 8| 9| 0| 1| 2| 3| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
PROSTATE | + + + + + + + + | |
AUTOLYSIS | 4 | |
CONGESTION | 4 | |
ECTASIA,FOCAL | 3 | |
SEMINAL VESICLE | + + + M + + + + + | |
AUTOLYSIS | | |
DEPLETION | | |
DISTENDED | 3 | |
INFLAMMATION,CHRONIC ACTIVE | 3 | |
TESTES | + + + A + + + + | |
AUTOLYSIS | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + | |
HYPERPLASIA | 3 2 | |
LYMPH NODE | + + + + + + + + + + + + | |
LYMPH NODE,MANDIBULAR | + + + A + + + + | |
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + | |
ANGIECTASIS,FOCAL | 4 | |
CONGESTION | 4| |
DEGENERATION | 2 2 3 3 4 | |
GRANULOMA | | |
HYPERPLASIA | 3 | |
SPLEEN | + + + + + A + + + + + | |
ANGIECTASIS,FOCAL | 3 | |
ATROPHY,LYMPHOCYTE | 3 | |
AUTOLYSIS | | |
HEMATOPOIETIC CELL PROLIFERATION | 3 4| |
HYPERPLASIA,LYMPHOID | 3 | |
THYMUS | + M + M M + M M | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M M M M M M M M | |
SKIN | + M + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 24
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:38.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 5| 5| 8| 2| 2| 4| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 2| 2| 1| 8| 9| 7| 5| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 3| S R R|
| 0| 6| 6| 7| 7| 7| 8| 9| 0| 0| 0| 0| 0| 0| 5| 6| 9| 9| 9| 9| 0| 0| 0| 0| 6| U V I|
50 MG/KGA 2YR 3 3 | 5| 5| 9| 2| 3| 8| 1| 9| 0| 1| 2| 3| 4| 5| 4| 9| 6| 7| 8| 9| 0| 1| 2| 3| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM
AUTOLYSIS | | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + | |
BONE,FEMUR | + + + + + + + + | |
BONE,STERNUM | + + + + + + + + | |
SKELETAL MUSCLE | + + + + + + + + | |
AUTOLYSIS | | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + A + + + + | |
BRAIN,CEREBELLUM | + + + A + + + + | |
BRAIN,CEREBRUM | + + + A + + + + | |
MINERALIZATION,THALAMUS | | |
PERIPHERAL NERVE | + + + + + + + + | |
AUTOLYSIS | | |
SPINAL CORD | + + + A + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + + + + + | |
AUTOLYSIS | | |
LUNG | + + + + + + + + + + | |
ATELECTASIS | | |
AUTOLYSIS | 3 | |
CONGESTION | 4 | |
HEMORRHAGE,FOCAL,ALVEOLUS | | |
NOSE | + + + + + + + + | |
AUTOLYSIS | | |
TRACHEA | + + + + + + + + | |
AUTOLYSIS | | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 25
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:38.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 5| 5| 8| 2| 2| 4| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 2| 2| 1| 8| 9| 7| 5| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 7|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 3| S R R|
| 0| 6| 6| 7| 7| 7| 8| 9| 0| 0| 0| 0| 0| 0| 5| 6| 9| 9| 9| 9| 0| 0| 0| 0| 6| U V I|
50 MG/KGA 2YR 3 3 | 5| 5| 9| 2| 3| 8| 1| 9| 0| 1| 2| 3| 4| 5| 4| 9| 6| 7| 8| 9| 0| 1| 2| 3| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + | |
AUTOLYSIS | 4 | |
HARDERIAN GLAND | + + + + + + + + + | |
AUTOLYSIS | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 2| |
LACRIMAL GLAND | + + + A + + + + | |
ZYMBAL'S GLAND | + + M + + + M + | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + | |
AUTOLYSIS | 2 3 4 | |
CONGESTION | 4 | |
GLOMERULOSCLEROSIS | | |
HYDRONEPHROSIS | 3 4 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
NEPHROPATHY | 4 | |
URINARY BLADDER | + + + + + + + + | |
AUTOLYSIS | 4 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 26
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:40.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 2| 3| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 8| 9| 7| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| S R R|
| 6| 7| 7| 8| 9| 9| 0| 0| 0| 0| 0| 0| 0| 0| 7| 7| 9| 0| 0| 0| 0| 0| 0| U V I|
50 MG/KGA 2YR 3 3 | 7| 6| 7| 0| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 0| 1| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + A + + | 11 |
AUTOLYSIS | 3 | 1 3.0|
GALLBLADDER | A A + + | 10 |
AUTOLYSIS | | 6 4.0|
CYST | | 1 |
INTESTINE LARGE | A A + + | 4 |
INTESTINE LARGE,CECUM | A A + + | 4 |
INTESTINE LARGE,COLON | A A + + | 4 |
INTESTINE LARGE,RECTUM | A A + + | 4 |
INTESTINE SMALL | A A + + | 5 |
INTESTINE SMALL,DUODENUM | A A + + | 4 |
INTESTINE SMALL,ILEUM | A A + + | 5 |
INTESTINE SMALL,JEJUNUM | A A + + | 4 |
LIVER | + A + + + + + + + + + + + + + + + + + + + + + | 47 |
BASOPHILIC FOCUS | X | 1 |
CLEAR CELL FOCUS | X X | 3 |
CLEAR CELL FOCUS,MULTIPLE | | 1 |
CLEAR CELL FOCUS,TWO | X | 1 |
CONGESTION | | 1 4.0|
EOSINOPHILIC FOCUS | X | 1 |
FIBROSIS,FOCAL | 2 | 1 2.0|
GRANULOMA,MULTIPLE | | 1 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
NECROSIS,FOCAL,HEPATOCYTE | 1 | 1 1.0|
VACUOLIZATION CYTOPLASMIC,CENTRILOBULAR | 2 | 2 1.5|
MESENTERY | | 1 |
PANCREAS | A A + + | 9 |
AUTOLYSIS | | 2 3.5|
SALIVARY GLANDS | + A + + | 10 |
STOMACH | A A + + | 10 |
STOMACH,FORESTOMACH | A A + + | 10 |
AUTOLYSIS | | 1 4.0|
STOMACH,GLANDULAR | A A + + | 10 |
AUTOLYSIS | | 5 3.8|
TONGUE | + A + + | 11 |
AUTOLYSIS | 3 | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 27
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:40.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 2| 3| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 8| 9| 7| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| S R R|
| 6| 7| 7| 8| 9| 9| 0| 0| 0| 0| 0| 0| 0| 0| 7| 7| 9| 0| 0| 0| 0| 0| 0| U V I|
50 MG/KGA 2YR 3 3 | 7| 6| 7| 0| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 0| 1| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + A + + | 11 |
HEART | + A + + | 11 |
AUTOLYSIS | | 1 3.0|
CONGESTION | | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | A A + + | 10 |
ADRENAL GLAND,CORTEX | A A + + | 10 |
AUTOLYSIS | 2 | 2 2.5|
HYPERPLASIA | 3 | 1 3.0|
HYPERPLASIA,SPINDLE CELL | 2 3 | 3 2.3|
ADRENAL GLAND,MEDULLA | A A + + | 10 |
AUTOLYSIS | | 1 3.0|
ISLETS, PANCREATIC | + + + + | 11 |
PARATHYROID GLAND | + A M + | 6 |
AUTOLYSIS | 3 | 1 3.0|
PITUITARY GLAND | A A + + + | 9 |
AUTOLYSIS | 2 | 1 2.0|
THYROID GLAND | + A + + | 10 |
AUTOLYSIS | 3 3 | 3 3.0|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + A + + | 10 |
AUTOLYSIS | 3 3 | 2 3.0|
DISTENDED | | 1 3.0|
INFLAMMATION,CHRONIC ACTIVE | | 1 3.0|
EPIDIDYMIS | + A + + | 11 |
AUTOLYSIS | 3 3 | 2 3.0|
INFLAMMATION,CHRONIC ACTIVE | | 1 3.0|
PREPUTIAL GLAND | + A A + | 11 |
ATROPHY | | 6 3.6|
AUTOLYSIS | 3 | 1 3.0|
CYST | | 1 |
ECTASIA,DUCT | | 5 3.6|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 28
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:40.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 2| 3| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 8| 9| 7| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| S R R|
| 6| 7| 7| 8| 9| 9| 0| 0| 0| 0| 0| 0| 0| 0| 7| 7| 9| 0| 0| 0| 0| 0| 0| U V I|
50 MG/KGA 2YR 3 3 | 7| 6| 7| 0| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 0| 1| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
PROSTATE | + A + + | 11 |
AUTOLYSIS | 3 3 | 3 3.3|
CONGESTION | | 1 4.0|
ECTASIA,FOCAL | | 1 3.0|
SEMINAL VESICLE | + A + + + + + | 14 |
AUTOLYSIS | 3 3 | 2 3.0|
DEPLETION | 3 | 1 3.0|
DISTENDED | 4 3 | 3 3.3|
INFLAMMATION,CHRONIC ACTIVE | | 1 3.0|
TESTES | + A + + | 10 |
AUTOLYSIS | 3 3 | 3 3.0|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | A A + + | 10 |
HYPERPLASIA | | 2 2.5|
LYMPH NODE | A A + + + + + | 17 |
LYMPH NODE,MANDIBULAR | M A + + | 9 |
LYMPH NODE,MESENTERIC | A A + + + + | 16 |
ANGIECTASIS,FOCAL | | 1 4.0|
CONGESTION | | 1 4.0|
DEGENERATION | | 5 2.8|
GRANULOMA | X | 1 |
HYPERPLASIA | | 1 3.0|
SPLEEN | A + + + + + + + | 17 |
ANGIECTASIS,FOCAL | | 1 3.0|
ATROPHY,LYMPHOCYTE | | 1 3.0|
AUTOLYSIS | 4 3 | 2 3.5|
HEMATOPOIETIC CELL PROLIFERATION | | 2 3.5|
HYPERPLASIA,LYMPHOID | 1 3 | 3 2.3|
THYMUS | M M M + | 4 |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M M M M | 0 |
SKIN | + A + + | 10 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 29
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:41.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 2| 3| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 8| 9| 7| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| S R R|
| 6| 7| 7| 8| 9| 9| 0| 0| 0| 0| 0| 0| 0| 0| 7| 7| 9| 0| 0| 0| 0| 0| 0| U V I|
50 MG/KGA 2YR 3 3 | 7| 6| 7| 0| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 0| 1| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM
AUTOLYSIS | 3 | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + | 12 |
BONE,FEMUR | + + + + | 12 |
BONE,STERNUM | + + + + | 12 |
SKELETAL MUSCLE | + A + + | 11 |
AUTOLYSIS | 3 | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + A A + | 9 |
BRAIN,CEREBELLUM | + A A + | 9 |
BRAIN,CEREBRUM | + A A + | 9 |
MINERALIZATION,THALAMUS | 2 | 1 2.0|
PERIPHERAL NERVE | + A + + | 11 |
AUTOLYSIS | 3 | 1 3.0|
SPINAL CORD | + A A + | 9 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + A + + | 11 |
AUTOLYSIS | 3 | 1 3.0|
LUNG | + A + + + + + | 16 |
ATELECTASIS | 4 | 1 4.0|
AUTOLYSIS | | 1 3.0|
CONGESTION | | 1 4.0|
HEMORRHAGE,FOCAL,ALVEOLUS | 2 | 1 2.0|
NOSE | + + + + | 12 |
AUTOLYSIS | 3 | 1 3.0|
TRACHEA | + A + + | 11 |
AUTOLYSIS | 3 | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 30
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:41.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 2| 3| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 8| 9| 7| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| S R R|
| 6| 7| 7| 8| 9| 9| 0| 0| 0| 0| 0| 0| 0| 0| 7| 7| 9| 0| 0| 0| 0| 0| 0| U V I|
50 MG/KGA 2YR 3 3 | 7| 6| 7| 0| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 0| 1| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
EYE | + A + + | 11 |
AUTOLYSIS | 3 | 2 3.5|
HARDERIAN GLAND | + A + + | 12 |
AUTOLYSIS | 3 | 1 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 2 2.0|
LACRIMAL GLAND | + A + + | 10 |
ZYMBAL'S GLAND | M A M + | 7 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | A A + + | 10 |
AUTOLYSIS | 3 | 4 3.0|
CONGESTION | | 1 4.0|
GLOMERULOSCLEROSIS | 3 | 1 3.0|
HYDRONEPHROSIS | | 2 3.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 1 2.0|
NEPHROPATHY | | 1 4.0|
URINARY BLADDER | + A + + | 11 |
AUTOLYSIS | 3 2 | 3 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 31
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:53.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 2| 6| 1| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 8| 0| 2| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 6| 6| 7| 0| 0| 0| 0| 1| 1| 1| 1| 5| 5| 7| 7| 0| 0| 0| 0| 0| 0| 1| 1| 1| 6| U V I|
100MG/KGA 2YR 4 4 | 2| 7| 1| 6| 7| 8| 9| 0| 1| 2| 3| 6| 7| 0| 1| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
POLYARTERITIS | | |
GALLBLADDER | M + M + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 4| |
FIBROSIS | 4 | |
INFLAMMATION,CHRONIC,SEROSA | | |
INTESTINE LARGE | + A + + + + + + + + + + + + + + + + + + + + + + A | |
INTESTINE LARGE,CECUM | + A + + + + + + + + + + + + + + + + + + + + + + A | |
AUTOLYSIS | 3 | |
HYPERPLASIA,LYMPHOID | 3 | |
POLYARTERITIS | | |
INTESTINE LARGE,COLON | + A + + + + + + + + + + + + + + + + + + + + + + A | |
AUTOLYSIS | 3 | |
POLYARTERITIS | | |
INTESTINE LARGE,RECTUM | M A + + + + + M + + + + + + + + + + + + + + M + A | |
POLYARTERITIS | | |
INTESTINE SMALL | + A + + + + + + + + + + + + + + + + + + + + + + A | |
INTESTINE SMALL,DUODENUM | + A + + + + + + + + + + + + + + + + + + + + + + A | |
AUTOLYSIS | 3 | |
INTESTINE SMALL,ILEUM | + A + + + + + + + + + + + + + + + + + + + + + + A | |
AUTOLYSIS | 3 | |
INTESTINE SMALL,JEJUNUM | + A + + + + + + + + + + + + + + + + + + + + + + A | |
AUTOLYSIS | 3 | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3| |
BASOPHILIC FOCUS | X X | |
CLEAR CELL FOCUS | X | |
CLEAR CELL FOCUS,TWO | | |
EOSINOPHILIC FOCUS | | |
INFARCT | X | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 2 | |
VACUOLIZATION CYTOPLASMIC,CENTRILOBULAR | 1 | |
PANCREAS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 4| |
POLYARTERITIS | | |
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 32
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:53.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 2| 6| 1| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 8| 0| 2| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 6| 6| 7| 0| 0| 0| 0| 1| 1| 1| 1| 5| 5| 7| 7| 0| 0| 0| 0| 0| 0| 1| 1| 1| 6| U V I|
100MG/KGA 2YR 4 4 | 2| 7| 1| 6| 7| 8| 9| 0| 1| 2| 3| 6| 7| 0| 1| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 2 1 2 1 | |
STOMACH | + A + + + + + + + + + + + + + + + + + + + + + + A | |
STOMACH,FORESTOMACH | + A + + + + + + + + + + + + + + + + + + + + + + A | |
STOMACH,GLANDULAR | + A + + + + + + + + + + + + + + + + + + + + + + A | |
INFLAMMATION,CHRONIC,FOCAL | | |
POLYARTERITIS | | |
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + M + | |
POLYARTERITIS | | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HEART | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CARDIOMYOPATHY | | |
POLYARTERITIS | | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + + + + + + + M + + + + + | |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + + + + + + + M + + + + + | |
AUTOLYSIS | 3| |
CYST,UNILATERAL | | |
CYTOPLASMIC ALTERATION | 2 | |
DEGENERATION,FOCAL,UNILATERAL | | |
HYPERPLASIA | 2 3 3 1 | |
HYPERPLASIA,SPINDLE CELL | 3 2 2 3 2 2 2 2 2 2 2 2 | |
ADRENAL GLAND,MEDULLA | + + + + + + + + + M + + + + + + + + + M + + + + + | |
AUTOLYSIS | 3| |
HYPERPLASIA | 1 | |
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
PARATHYROID GLAND | + + + + + + + + + + + + + + + + + M + M + + + + + | |
PITUITARY GLAND | + M + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3| |
CYST | X | |
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CYST,FOLLICLE | X | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 33
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:53.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 2| 6| 1| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 8| 0| 2| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 6| 6| 7| 0| 0| 0| 0| 1| 1| 1| 1| 5| 5| 7| 7| 0| 0| 0| 0| 0| 0| 1| 1| 1| 6| U V I|
100MG/KGA 2YR 4 4 | 2| 7| 1| 6| 7| 8| 9| 0| 1| 2| 3| 6| 7| 0| 1| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
POLYARTERITIS | | |
------------------------------------------------------------------------------------------------------------------------------------
GENERAL BODY SYSTEM
TISSUE NOS | + + | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DISTENDED | 4| |
EPIDIDYMIS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 4| |
GRANULOMA SPERM | | |
GRANULOMA,UNILATERAL | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
POLYARTERITIS | | |
PENIS | + | |
CONCRETION | 3| |
INFLAMMATION,ACUTE | 4| |
PREPUTIAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 2 3 3 2 2 3 4 3| |
CYST | X X | |
DILATATION | | |
ECTASIA,DUCT | | |
INFLAMMATION,ACUTE,UNILATERAL | | |
PROSTATE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 2 | |
INFLAMMATION,ACUTE | 3| |
INFLAMMATION,FOCAL | | |
POLYARTERITIS | | |
SEMINAL VESICLE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 2 | |
AUTOLYSIS | 4| |
DILATATION | 4| |
INFLAMMATION,CHRONIC | 3 | |
POLYARTERITIS,UNILATERAL | | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 34
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:53.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 2| 6| 1| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 8| 0| 2| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 6| 6| 7| 0| 0| 0| 0| 1| 1| 1| 1| 5| 5| 7| 7| 0| 0| 0| 0| 0| 0| 1| 1| 1| 6| U V I|
100MG/KGA 2YR 4 4 | 2| 7| 1| 6| 7| 8| 9| 0| 1| 2| 3| 6| 7| 0| 1| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
TESTES | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 4| |
HYPERPLASIA,UNILATERAL,INTERSTITIAL CELL | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | 3 3 | |
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
LYMPH NODE,MANDIBULAR | + M + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | 2 | |
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CONGESTION | 2 | |
DEGENERATION | | |
HEMORRHAGE | 3 | |
HYPERPLASIA | 3 3 3 | |
POLYARTERITIS,ARTERY | | |
SPLEEN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY,LYMPHOCYTE | 3 2 | |
HEMATOPOIETIC CELL PROLIFERATION | 2 2 4 3 | |
HYPERPLASIA,LYMPHOID | 2 | |
THYMUS | + + M + + M + M + + + M + + M + + + + + + + + + + | |
AUTOLYSIS | 3| |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M M + M + M M M M M M M M M M M M M M M M M M M M | |
SKIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY | 2 | |
POLYARTERITIS | | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 35
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:54.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 2| 6| 1| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 8| 0| 2| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 6| 6| 7| 0| 0| 0| 0| 1| 1| 1| 1| 5| 5| 7| 7| 0| 0| 0| 0| 0| 0| 1| 1| 1| 6| U V I|
100MG/KGA 2YR 4 4 | 2| 7| 1| 6| 7| 8| 9| 0| 1| 2| 3| 6| 7| 0| 1| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
POLYARTERITIS | | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 4| |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 4| |
HYDROCEPHALUS | | |
MINERALIZATION,THALAMUS | 2 3 2 2 2 3 2 1 2 | |
PERIPHERAL NERVE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DEGENERATION | | |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3| |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + + + + + + + + + + + + + + + + + + M + + + | |
POLYARTERITIS | | |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DILATATION,BRONCHIOLE,GLANDS | | |
HYPERPLASIA,ALVEOLAR EPITHELIUM | 2 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
POLYARTERITIS | | |
NOSE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
TRACHEA | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
POLYARTERITIS | | |
HARDERIAN GLAND | + M + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,DIFFUSE,UNILATERAL | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 36
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:30:54.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 2| 6| 1| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 8| 0| 2| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 6| 6| 7| 0| 0| 0| 0| 1| 1| 1| 1| 5| 5| 7| 7| 0| 0| 0| 0| 0| 0| 1| 1| 1| 6| U V I|
100MG/KGA 2YR 4 4 | 2| 7| 1| 6| 7| 8| 9| 0| 1| 2| 3| 6| 7| 0| 1| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
HYPERPLASIA,FOCAL,BILATERAL | | |
HYPERPLASIA,FOCAL,UNILATERAL | 3 | |
HYPERPLASIA,PAPILLARY,UNILATERAL | 3 | |
HYPERPLASIA,UNILATERAL | 4 | |
LACRIMAL GLAND | + M + + + + + M + + + + + + + + + + + + + + + + + | |
CYTOPLASMIC ALTERATION | 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 1 | |
ZYMBAL'S GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | | |
AUTOLYSIS | 3| |
CYST,RENAL TUBULE | X X | |
DEGENERATION,RENAL TUBULE | 1 2 3 | |
GLOMERULOSCLEROSIS | 2 1 2 | |
INFARCT,UNILATERAL | 4 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 2 | |
MINERALIZATION,RENAL TUBULE | 1 1 | |
NEPHROPATHY | | |
REGENERATION,RENAL TUBULE | 1 2 2 1 2 1 3 | |
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFLAMMATION,ACUTE | 2| |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 37
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:05.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 5| 7| 7| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| U V I|
100MG/KGA 2YR 4 4 | 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 9| 2| 3| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
POLYARTERITIS | 4 | 1 4.0|
GALLBLADDER | + + + + + + + + + + + M M + + + + + + + + + + | 44 |
AUTOLYSIS | | 1 4.0|
FIBROSIS | 4 | 2 4.0|
INFLAMMATION,CHRONIC,SEROSA | 3 | 1 3.0|
INTESTINE LARGE | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
INTESTINE LARGE,CECUM | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
AUTOLYSIS | | 1 3.0|
HYPERPLASIA,LYMPHOID | | 1 3.0|
POLYARTERITIS | 4 | 1 4.0|
INTESTINE LARGE,COLON | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
AUTOLYSIS | | 1 3.0|
POLYARTERITIS | 4 | 1 4.0|
INTESTINE LARGE,RECTUM | + + + + + + + + + + + + + + + + + + + + + + + | 43 |
POLYARTERITIS | 4 | 1 4.0|
INTESTINE SMALL | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
INTESTINE SMALL,DUODENUM | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
AUTOLYSIS | | 1 3.0|
INTESTINE SMALL,ILEUM | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
AUTOLYSIS | | 1 3.0|
INTESTINE SMALL,JEJUNUM | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
AUTOLYSIS | | 1 3.0|
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 1 3.0|
BASOPHILIC FOCUS | X X X | 5 |
CLEAR CELL FOCUS | X | 2 |
CLEAR CELL FOCUS,TWO | X | 1 |
EOSINOPHILIC FOCUS | X | 1 |
INFARCT | X | 2 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 2 2.0|
VACUOLIZATION CYTOPLASMIC,CENTRILOBULAR | 1 1 1 | 4 1.0|
PANCREAS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 1 4.0|
POLYARTERITIS | 4 | 1 4.0|
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 38
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:05.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 5| 7| 7| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| U V I|
100MG/KGA 2YR 4 4 | 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 9| 2| 3| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 1 2 3 2 | 10 2.0|
STOMACH | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
STOMACH,FORESTOMACH | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
STOMACH,GLANDULAR | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
INFLAMMATION,CHRONIC,FOCAL | 3 | 1 3.0|
POLYARTERITIS | 4 | 1 4.0|
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
POLYARTERITIS | 4 | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HEART | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
CARDIOMYOPATHY | 2 | 1 2.0|
POLYARTERITIS | 4 | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + M + + + + + + + + + + + | 46 |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + M + + + + + + + + + + + | 46 |
AUTOLYSIS | | 1 3.0|
CYST,UNILATERAL | X | 1 |
CYTOPLASMIC ALTERATION | 2 2 2 3 | 5 2.2|
DEGENERATION,FOCAL,UNILATERAL | 3 | 1 3.0|
HYPERPLASIA | | 4 2.2|
HYPERPLASIA,SPINDLE CELL | 2 2 2 3 2 2 3 2 2 3 2 2 1 1 2 | 27 2.1|
ADRENAL GLAND,MEDULLA | + + + + + + + + + + + M + + + + + + + + + + + | 45 |
AUTOLYSIS | | 1 3.0|
HYPERPLASIA | | 1 1.0|
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
PARATHYROID GLAND | + + + M M + + + + + M + + + M + + + + + + + + | 42 |
PITUITARY GLAND | + + + + + + + + + + + + + + + + + + + + + M + | 46 |
AUTOLYSIS | | 1 3.0|
CYST | | 1 |
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
CYST,FOLLICLE | X X | 3 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 39
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:06.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 5| 7| 7| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| U V I|
100MG/KGA 2YR 4 4 | 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 9| 2| 3| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
POLYARTERITIS | 4 | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
GENERAL BODY SYSTEM
TISSUE NOS | | 2 |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
DISTENDED | | 1 4.0|
EPIDIDYMIS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 1 4.0|
GRANULOMA SPERM | 3 4 | 2 3.5|
GRANULOMA,UNILATERAL | X | 1 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 | 1 3.0|
POLYARTERITIS | 4 | 1 4.0|
PENIS | | 1 |
CONCRETION | | 1 3.0|
INFLAMMATION,ACUTE | | 1 4.0|
PREPUTIAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY | 4 4 1 4 3 3 2 1 2 2 2 2 | 21 2.6|
CYST | X | 3 |
DILATATION | 3 | 1 3.0|
ECTASIA,DUCT | 3 2 | 2 2.5|
INFLAMMATION,ACUTE,UNILATERAL | 3 | 1 3.0|
PROSTATE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY | 3 2 | 3 2.3|
INFLAMMATION,ACUTE | | 1 3.0|
INFLAMMATION,FOCAL | 3 | 1 3.0|
POLYARTERITIS | 4 | 1 4.0|
SEMINAL VESICLE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY | 3 | 2 2.5|
AUTOLYSIS | | 1 4.0|
DILATATION | | 1 4.0|
INFLAMMATION,CHRONIC | | 1 3.0|
POLYARTERITIS,UNILATERAL | 4 | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 40
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:06.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 5| 7| 7| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| U V I|
100MG/KGA 2YR 4 4 | 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 9| 2| 3| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
TESTES | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 1 4.0|
HYPERPLASIA,UNILATERAL,INTERSTITIAL CELL | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HYPERPLASIA | 3 2 | 4 2.7|
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + M M + + + + + + + + | 45 |
HYPERPLASIA | | 1 2.0|
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
CONGESTION | | 1 2.0|
DEGENERATION | 3 2 2 3 2 | 5 2.4|
HEMORRHAGE | | 1 3.0|
HYPERPLASIA | 3 | 4 3.0|
POLYARTERITIS,ARTERY | 4 | 1 4.0|
SPLEEN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY,LYMPHOCYTE | | 2 2.5|
HEMATOPOIETIC CELL PROLIFERATION | 4 4 3 | 7 3.1|
HYPERPLASIA,LYMPHOID | | 1 2.0|
THYMUS | + M + M + + + M + M + M + + M + + + M + + M + | 35 |
AUTOLYSIS | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M M M M M M M M M M M M M M M M M M M M M M M | 2 |
SKIN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
FIBROUS OSTEODYSTROPHY | 2 | 2 2.0|
POLYARTERITIS | 4 | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 41
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:06.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 5| 7| 7| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| U V I|
100MG/KGA 2YR 4 4 | 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 9| 2| 3| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 2.0|
POLYARTERITIS | 4 1 | 2 2.5|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 1 4.0|
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 1 4.0|
HYDROCEPHALUS | 3 | 1 3.0|
MINERALIZATION,THALAMUS | 3 2 3 2 1 | 14 2.1|
PERIPHERAL NERVE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
DEGENERATION | 1 | 1 1.0|
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
POLYARTERITIS | 4 | 1 4.0|
LUNG | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
DILATATION,BRONCHIOLE,GLANDS | 4 | 1 4.0|
HYPERPLASIA,ALVEOLAR EPITHELIUM | | 2 1.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 | 2 2.5|
POLYARTERITIS | 4 | 1 4.0|
NOSE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
TRACHEA | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
POLYARTERITIS | 4 | 1 4.0|
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
HYPERPLASIA,DIFFUSE,UNILATERAL | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 42
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:06.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 5| 7| 7| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| U V I|
100MG/KGA 2YR 4 4 | 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 9| 2| 3| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
HYPERPLASIA,FOCAL,BILATERAL | 3 | 1 3.0|
HYPERPLASIA,FOCAL,UNILATERAL | | 1 3.0|
HYPERPLASIA,PAPILLARY,UNILATERAL | | 1 3.0|
HYPERPLASIA,UNILATERAL | | 1 4.0|
LACRIMAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
CYTOPLASMIC ALTERATION | | 1 1.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 2 1.5|
ZYMBAL'S GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ANGIECTASIS | 4 | 1 4.0|
AUTOLYSIS | | 1 3.0|
CYST,RENAL TUBULE | X | 3 |
DEGENERATION,RENAL TUBULE | | 3 2.0|
GLOMERULOSCLEROSIS | 3 2 2 3 2 1 2 | 10 2.0|
INFARCT,UNILATERAL | | 1 4.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 3 2.0|
MINERALIZATION,RENAL TUBULE | 1 | 3 1.0|
NEPHROPATHY | 1 2 1 | 3 1.3|
REGENERATION,RENAL TUBULE | | 7 1.7|
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFLAMMATION,ACUTE | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 43
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:06.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
| 2| 2| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| S R R|
| 0| 1| 1| 3| 3| 3| 1| 1| 1| 3| 3| 3| U V I|
CONTROL A 64WK 5 5 | 9| 0| 1| 4| 5| 6| 1| 2| 3| 5| 6| 7| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
LIVER | + + + + + + + + + + + + | 12 |
FATTY CHANGE,FOCAL,PERIPHERAL | 1 1 | 2 1.0|
GRANULOMA,MULTIPLE | X X X | 3 |
VACUOLIZATION CYTOPLASMIC,CENTRILOBULAR | 2 2 2 2 1 2 2 2 2 | 9 1.8|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 44
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:07.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
| 2| 2| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| S R R|
| 1| 1| 1| 3| 3| 3| 1| 1| 1| 3| 3| 4| U V I|
25MG/KG A 64W 6 6 | 2| 3| 4| 7| 8| 9| 4| 5| 6| 8| 9| 0| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
LIVER | + + + + + + + + + + + + | 12 |
FATTY CHANGE,FOCAL,PERIPHERAL | 1 2 3 1 3 2 3 | 7 2.1|
VACUOLIZATION CYTOPLASMIC,CENTRILOBULAR | 1 2 2 2 2 3 | 6 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 45
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:07.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
| 2| 2| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| S R R|
| 1| 1| 1| 4| 4| 4| 1| 1| 1| 4| 4| 4| U V I|
50 MG/KGA 64W 7 7 | 5| 6| 7| 0| 1| 2| 7| 8| 9| 1| 2| 3| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
LIVER | + + + + + + + + + + + + | 12 |
FATTY CHANGE,PERIPHERAL | 3 1 1 1 3 3 2 | 7 2.0|
VACUOLIZATION CYTOPLASMIC,CENTRILOBULAR | 2 3 1 1 1 1 1 | 7 1.4|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 46
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:07.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
| 2| 2| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| S R R|
| 1| 1| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4| U V I|
100MG/KGA 64W 8 8 | 8| 9| 0| 3| 4| 5| 0| 1| 2| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
LIVER | + + + + + + + + + + + + | 12 |
FATTY CHANGE,PERIPHERAL | 2 3 1 1 2 1 1 | 7 1.5|
VACUOLIZATION CYTOPLASMIC,CENTRILOBULAR | 2 1 2 2 | 4 1.7|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 47
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:16.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 4|
| 3| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 9|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 8| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 5| 5| 7| 7| 1| 1| 1| 1| 1| 1| 1| 2| 2| 0| U V I|
CONTROL R 2YR 10 10 | 0| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 5| 8| 2| 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + + + + + + + + + + M + + + + + + | |
GALLBLADDER | + + M + + + + + + + + + + + + + + + + + + + + + + | |
INTESTINE LARGE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INTESTINE LARGE,CECUM | + + + + + + + + + + + M M + + + + + + + + + + + + | |
INTESTINE LARGE,COLON | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INTESTINE LARGE,RECTUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INTESTINE SMALL | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INTESTINE SMALL,DUODENUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INTESTINE SMALL,ILEUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INTESTINE SMALL,JEJUNUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CLEAR CELL FOCUS | | |
INFARCT | X | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
MIXED CELL FOCUS | X | |
NECROSIS,HEPATOCYTE | 3 | |
PANCREAS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY,ACINAR CELL | 3 3| |
CYST,DUCT | X | |
DILATATION,DUCT | 3 | |
HYPERPLASIA,LYMPHOID | 3 | |
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 2 2 | |
STOMACH | + + + + + + + + + + + + + + + + + + + + + + + + + | |
STOMACH,FORESTOMACH | + + + + + + + + + + + + + + + + + + + + + + + + + | |
STOMACH,GLANDULAR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CYST | X | |
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ARTERIOSCLEROSIS,ARTERY | 2 2| |
MINERALIZATION,AORTA | 1 | |
HEART | + + + + + + + + + + + + + + + + + + + + + + + + + | |
CARDIOMYOPATHY | 2 1 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 48
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:16.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 4|
| 3| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 9|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 8| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 5| 5| 7| 7| 1| 1| 1| 1| 1| 1| 1| 2| 2| 0| U V I|
CONTROL R 2YR 10 10 | 0| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 5| 8| 2| 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + M + + + + + + + + + + + + + + + + + | |
ADRENAL GLAND,CORTEX | + + + + + + + M + + + + + + + + + + + + + + + + + | |
CYTOPLASMIC ALTERATION | 2 | |
HYPERPLASIA | 3 2 3 2 | |
HYPERPLASIA,SPINDLE CELL | 2 2 2 2 2 2 3 2 2 1 2 2 3 3 | |
ADRENAL GLAND,MEDULLA | + + + + + + + M + + + + + + + + + + + + + + + + + | |
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
PARATHYROID GLAND | + + + + + + + + + + + + M + + + + + M + + + + M M | |
PITUITARY GLAND | + + + M + + + + + + + + + + + + + + + + M + + + + | |
THYROID GLAND | + + + + + + + + + + + + + + + + + + M + + + + + + | |
CYST,FOLLICLE | X X | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
EPIDIDYMIS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
PREPUTIAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 2 2 1 3 3 2| |
ECTASIA,DUCT | | |
PROSTATE | + + + + + + + + + + + + + + + + + + + + + + + + M | |
SEMINAL VESICLE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
TESTES | + + + + + + + + + + + + + + + + + + + + + + + + + | |
DEGENERATION,UNILATERAL,SEMINIFEROUS TUBUL| | |
E | | |
MINERALIZATION,UNILATERAL,SEMINIFEROUS TUB| | |
ULE | | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA | | |
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
LYMPH NODE,MANDIBULAR | + + + M + + + + + + + + + + + + + + + + + + + + + | |
ANGIECTASIS | 3 | |
LYMPH NODE,MESENTERIC | M + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 49
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:16.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 4|
| 3| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 9|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 8| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 5| 5| 7| 7| 1| 1| 1| 1| 1| 1| 1| 2| 2| 0| U V I|
CONTROL R 2YR 10 10 | 0| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 5| 8| 2| 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
DEGENERATION | | |
HYPERPLASIA | 3 3 | |
SPLEEN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY,LYMPHOCYTE | 3 | |
HEMATOPOIETIC CELL PROLIFERATION | 3 2 | |
HYPERPLASIA,LYMPHOID | 3 2 | |
THYMUS | + + M + + + + + + + + M M + + + + + + + + + + M M | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M M M M M M M M M M M M M M M M M M M M M M M M M | |
SKIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
FIBROUS OSTEODYSTROPHY | 2 2 | |
OSTEOPETROSIS | 3 | |
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC,LATERAL | | |
VENTRICLE | | |
MINERALIZATION,THALAMUS | 2 1 3 1 2 2 2 2 2 2 1 | |
PERIPHERAL NERVE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 50
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:16.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 4|
| 3| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 9|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 8| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 5| 5| 7| 7| 1| 1| 1| 1| 1| 1| 1| 2| 2| 0| U V I|
CONTROL R 2YR 10 10 | 0| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 5| 8| 2| 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM
LARYNX | + + + + + + + + + + + + + + + + + + M + + + + + M | |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATELECTASIS | | |
GRANULOMA,FOCAL | X | |
HEMORRHAGE | 1 | |
HYPERPLASIA,ALVEOLAR EPITHELIUM | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 2 | |
NOSE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
TRACHEA | + + + + + + + + + + + + + + + + + + M + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
HYPERPLASIA,UNILATERAL | 1 | |
LACRIMAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
ZYMBAL'S GLAND | M + + + + + + + + + + + + + + + + + + + + + + + + | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ACCUMULATION HYALINE DROPLET,RENAL TUBULE | 2 | |
CYST,RENAL TUBULE | X | |
DEGENERATION,RENAL TUBULE | 2 | |
GLOMERULOSCLEROSIS | 2 | |
HYPERPLASIA,FOCAL,UNILATERAL,RENAL TUBULE | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
MINERALIZATION,RENAL TUBULE | 2 | |
NEPHROPATHY | 1 | |
REGENERATION,RENAL TUBULE | 1 3 | |
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 51
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:23.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 1| 1| 2| 2| 2| 2| 2| 2| 2| 6| 6| 7| 7| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| U V I|
CONTROL R 2YR 10 10 | 8| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 4| 5| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
GALLBLADDER | A + + + + + + + + + + + + + + + + + + + + + + | 46 |
INTESTINE LARGE | A + + + + + + + + + + + + + + + + + + + + + + | 47 |
INTESTINE LARGE,CECUM | A + + + + + + + + + + + + + + + + + + + + + + | 45 |
INTESTINE LARGE,COLON | A + + + + + + + + + + + + + + + + + + + + + + | 47 |
INTESTINE LARGE,RECTUM | A + + + + + + + + + + + + + + + + + + + + + + | 47 |
INTESTINE SMALL | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INTESTINE SMALL,DUODENUM | A + + + + + + + + + + + + + + + + + + + + + + | 47 |
INTESTINE SMALL,ILEUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INTESTINE SMALL,JEJUNUM | A + + + + + + + + + + + + + + + + + + + + + + | 47 |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
CLEAR CELL FOCUS | X | 1 |
INFARCT | | 1 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
MIXED CELL FOCUS | | 1 |
NECROSIS,HEPATOCYTE | | 1 3.0|
PANCREAS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY,ACINAR CELL | | 2 3.0|
CYST,DUCT | | 1 |
DILATATION,DUCT | | 1 3.0|
HYPERPLASIA,LYMPHOID | | 1 3.0|
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 2 | 5 2.4|
STOMACH | A + + + + + + + + + + + + + + + + + + + + + + | 47 |
STOMACH,FORESTOMACH | A + + + + + + + + + + + + + + + + + + + + + + | 47 |
STOMACH,GLANDULAR | A + + + + + + + + + + + + + + + + + + + + + + | 47 |
CYST | | 1 |
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ARTERIOSCLEROSIS,ARTERY | | 2 2.0|
MINERALIZATION,AORTA | | 1 1.0|
HEART | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
CARDIOMYOPATHY | 1 | 3 1.3|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 52
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:23.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 1| 1| 2| 2| 2| 2| 2| 2| 2| 6| 6| 7| 7| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| U V I|
CONTROL R 2YR 10 10 | 8| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 4| 5| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM
ADRENAL GLAND | A + + + + + + + + + + + + + + + + M + + + + + | 45 |
ADRENAL GLAND,CORTEX | A + + + + + + + + + + + + + + + + M + + + + + | 45 |
CYTOPLASMIC ALTERATION | | 1 2.0|
HYPERPLASIA | | 4 2.5|
HYPERPLASIA,SPINDLE CELL | 3 2 2 2 1 2 2 2 1 2 1 2 3 2 2 2 2 2 2 | 33 2.0|
ADRENAL GLAND,MEDULLA | A + + + + + + + + + + + + + + + + M + + + + + | 45 |
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
PARATHYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 44 |
PITUITARY GLAND | A + + + + + + + + + + M + + + + + M + + + + + | 43 |
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
CYST,FOLLICLE | X | 3 |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
EPIDIDYMIS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
PREPUTIAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY | 3 1 2 2 4 2 2 | 13 2.2|
ECTASIA,DUCT | 4 | 1 4.0|
PROSTATE | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
SEMINAL VESICLE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
TESTES | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
DEGENERATION,UNILATERAL,SEMINIFEROUS TUBUL| 2 | 1 2.0|
E | | |
MINERALIZATION,UNILATERAL,SEMINIFEROUS TUB| 2 | 1 2.0|
ULE | | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HYPERPLASIA | 3 | 1 3.0|
LYMPH NODE | + + + + + + + M + + + + + + + + + + + + + + + | 47 |
LYMPH NODE,MANDIBULAR | + + + + + + + M + + + + + + + + + + + + + + + | 46 |
ANGIECTASIS | | 1 3.0|
LYMPH NODE,MESENTERIC | + + + + + M M M + + + + + + + + + + + + + + + | 44 |
ATROPHY | | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 53
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:23.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 1| 1| 2| 2| 2| 2| 2| 2| 2| 6| 6| 7| 7| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| U V I|
CONTROL R 2YR 10 10 | 8| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 4| 5| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
DEGENERATION | 2 3 3 3 | 4 2.7|
HYPERPLASIA | | 2 3.0|
SPLEEN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY,LYMPHOCYTE | | 1 3.0|
HEMATOPOIETIC CELL PROLIFERATION | | 2 2.5|
HYPERPLASIA,LYMPHOID | | 2 2.5|
THYMUS | M + + M + + + + M + + + + M + + + + + + + + + | 39 |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M M M M M M M M M M M M M M M M M M M M M M M | 0 |
SKIN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
FIBROUS OSTEODYSTROPHY | | 2 2.0|
OSTEOPETROSIS | | 1 3.0|
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC,LATERAL | 1 | 1 1.0|
VENTRICLE | | |
MINERALIZATION,THALAMUS | 2 2 1 2 3 3 2 2 | 19 1.9|
PERIPHERAL NERVE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 54
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:23.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 1| 1| 2| 2| 2| 2| 2| 2| 2| 6| 6| 7| 7| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| U V I|
CONTROL R 2YR 10 10 | 8| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 4| 5| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM
LARYNX | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATELECTASIS | 3 | 1 3.0|
GRANULOMA,FOCAL | | 1 |
HEMORRHAGE | | 1 1.0|
HYPERPLASIA,ALVEOLAR EPITHELIUM | 2 | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 | 3 2.3|
NOSE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
TRACHEA | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
HYPERPLASIA,UNILATERAL | | 1 1.0|
LACRIMAL GLAND | + + + + + + M + + + + + + + + + + + + + + + + | 47 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 1.0|
ZYMBAL'S GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ACCUMULATION HYALINE DROPLET,RENAL TUBULE | | 1 2.0|
CYST,RENAL TUBULE | | 1 |
DEGENERATION,RENAL TUBULE | | 1 2.0|
GLOMERULOSCLEROSIS | 1 | 2 1.5|
HYPERPLASIA,FOCAL,UNILATERAL,RENAL TUBULE | 2 | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 2.0|
MINERALIZATION,RENAL TUBULE | | 1 2.0|
NEPHROPATHY | | 1 1.0|
REGENERATION,RENAL TUBULE | | 2 2.0|
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 55
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:25.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 1| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 8| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1|
| 4| 4| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 0| 6| 2| 2| 2| 2| 2| 2| 3| 3| 3| 5| 6| 7| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 6| U V I|
25MG/KG R 2YR 11 11 | 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 9| 0| 4| 5| 2| 3| 4| 5| 6| 7| 8| 9| 0| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + | |
GALLBLADDER | + + + | |
INTESTINE LARGE | + + + | |
INTESTINE LARGE,CECUM | + + + | |
AUTOLYSIS | 4 | |
INTESTINE LARGE,COLON | + + + | |
AUTOLYSIS | 3 | |
INTESTINE LARGE,RECTUM | + + + | |
AUTOLYSIS | 3 | |
INTESTINE SMALL | + + + + | |
INTESTINE SMALL,DUODENUM | + + + | |
AUTOLYSIS | 4 | |
ULCER | | |
INTESTINE SMALL,ILEUM | + + + | |
AUTOLYSIS | 3 | |
INTESTINE SMALL,JEJUNUM | + + + + | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BASOPHILIC FOCUS | | |
CLEAR CELL FOCUS | | |
EOSINOPHILIC FOCUS | X | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 1| |
NECROSIS,HEPATOCYTE,MIDZONAL | | |
VACUOLIZATION CYTOPLASMIC,CENTRILOBULAR | | |
PANCREAS | + + + | |
SALIVARY GLANDS | + + + | |
STOMACH | + + + | |
STOMACH,FORESTOMACH | + + + | |
HYPERPLASIA,FOCAL | | |
METAPLASIA,SQUAMOUS | | |
STOMACH,GLANDULAR | + + + | |
AUTOLYSIS | 3 | |
TONGUE | + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 56
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:25.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 1| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 8| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1|
| 4| 4| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 0| 6| 2| 2| 2| 2| 2| 2| 3| 3| 3| 5| 6| 7| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 6| U V I|
25MG/KG R 2YR 11 11 | 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 9| 0| 4| 5| 2| 3| 4| 5| 6| 7| 8| 9| 0| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + | |
HEART | + + + | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + | |
ADRENAL GLAND,CORTEX | + + + | |
ADRENAL GLAND,MEDULLA | + + + | |
ISLETS, PANCREATIC | + + + | |
PARATHYROID GLAND | + + + | |
PITUITARY GLAND | + M + | |
THYROID GLAND | + + + | |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + + + | |
AUTOLYSIS | | |
EPIDIDYMIS | + + + | |
AUTOLYSIS | | |
PREPUTIAL GLAND | + + + | |
ATROPHY | 4 3| |
AUTOLYSIS | | |
ECTASIA,DUCT | 3 | |
PROSTATE | + + + | |
SEMINAL VESICLE | + + + | |
AUTOLYSIS | | |
TESTES | + + + | |
AUTOLYSIS | | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + | |
HYPERPLASIA | 2 | |
LYMPH NODE | + + + + + | |
LYMPH NODE,MANDIBULAR | + M + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 57
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:25.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 1| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 8| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1|
| 4| 4| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 0| 6| 2| 2| 2| 2| 2| 2| 3| 3| 3| 5| 6| 7| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 6| U V I|
25MG/KG R 2YR 11 11 | 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 9| 0| 4| 5| 2| 3| 4| 5| 6| 7| 8| 9| 0| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
APOPTOSIS,LYMPHOCYTE | 3 | |
LYMPH NODE,MESENTERIC | + + + + + | |
APOPTOSIS,LYMPHOCYTE | 4 | |
DEGENERATION | | |
SPLEEN | + + + M | |
APOPTOSIS,LYMPHOCYTE | 4 | |
HEMATOPOIETIC CELL PROLIFERATION | 3 | |
THYMUS | M + + | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M M M | |
SKIN | + + + | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + | |
BONE,FEMUR | + + + | |
BONE,STERNUM | + + + | |
SKELETAL MUSCLE | + + + | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + + + | |
BRAIN,CEREBELLUM | + + + | |
BRAIN,CEREBRUM | + + + | |
HYDROCEPHALUS | 2 | |
MINERALIZATION,THALAMUS | 2 | |
PERIPHERAL NERVE | + + + | |
SPINAL CORD | M + + | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + | |
LUNG | + + + + | |
NOSE | + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 58
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:25.6
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 1| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 8| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1|
| 4| 4| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 0| 6| 2| 2| 2| 2| 2| 2| 3| 3| 3| 5| 6| 7| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 6| U V I|
25MG/KG R 2YR 11 11 | 3| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 9| 0| 4| 5| 2| 3| 4| 5| 6| 7| 8| 9| 0| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM
TRACHEA | + + + | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EAR | + | |
EYE | + + + | |
HARDERIAN GLAND | + + + + | |
LACRIMAL GLAND | + + + | |
ZYMBAL'S GLAND | + + + | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + | |
INFARCT,UNILATERAL | 3 | |
URINARY BLADDER | + + + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 59
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:26.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 7| 2| 2| 2| 3| 3| 3| 3| 3| 3| 6| 6| 7| 7| 2| 2| 2| 3| 3| 3| 3| 3| 3| U V I|
25MG/KG R 2YR 11 11 | 2| 7| 8| 9| 0| 1| 2| 3| 4| 5| 2| 3| 6| 7| 7| 8| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + | 4 |
GALLBLADDER | + | 4 |
INTESTINE LARGE | + | 4 |
INTESTINE LARGE,CECUM | + | 4 |
AUTOLYSIS | | 1 4.0|
INTESTINE LARGE,COLON | + | 4 |
AUTOLYSIS | | 1 3.0|
INTESTINE LARGE,RECTUM | + | 4 |
AUTOLYSIS | | 1 3.0|
INTESTINE SMALL | + | 5 |
INTESTINE SMALL,DUODENUM | + | 4 |
AUTOLYSIS | | 1 4.0|
ULCER | 4 | 1 4.0|
INTESTINE SMALL,ILEUM | + | 4 |
AUTOLYSIS | | 1 3.0|
INTESTINE SMALL,JEJUNUM | + | 5 |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BASOPHILIC FOCUS | X | 1 |
CLEAR CELL FOCUS | X | 1 |
EOSINOPHILIC FOCUS | X | 2 |
INFILTRATION CELLULAR,LYMPHOCYTIC | | 2 1.0|
NECROSIS,HEPATOCYTE,MIDZONAL | 4 | 1 4.0|
VACUOLIZATION CYTOPLASMIC,CENTRILOBULAR | 3 | 1 3.0|
PANCREAS | + | 4 |
SALIVARY GLANDS | + | 4 |
STOMACH | + + | 5 |
STOMACH,FORESTOMACH | + + | 5 |
HYPERPLASIA,FOCAL | 1 | 1 1.0|
METAPLASIA,SQUAMOUS | 2 | 1 2.0|
STOMACH,GLANDULAR | + + | 5 |
AUTOLYSIS | | 1 3.0|
TONGUE | + | 4 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 60
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:26.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 7| 2| 2| 2| 3| 3| 3| 3| 3| 3| 6| 6| 7| 7| 2| 2| 2| 3| 3| 3| 3| 3| 3| U V I|
25MG/KG R 2YR 11 11 | 2| 7| 8| 9| 0| 1| 2| 3| 4| 5| 2| 3| 6| 7| 7| 8| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + | 4 |
HEART | + | 4 |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + | 4 |
ADRENAL GLAND,CORTEX | + | 4 |
ADRENAL GLAND,MEDULLA | + | 4 |
ISLETS, PANCREATIC | + | 4 |
PARATHYROID GLAND | M | 3 |
PITUITARY GLAND | M + | 3 |
THYROID GLAND | + | 4 |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM
COAGULATING GLAND | + | 4 |
AUTOLYSIS | 3 | 1 3.0|
EPIDIDYMIS | + | 4 |
AUTOLYSIS | 3 | 1 3.0|
PREPUTIAL GLAND | + | 4 |
ATROPHY | | 2 3.5|
AUTOLYSIS | 3 | 1 3.0|
ECTASIA,DUCT | | 1 3.0|
PROSTATE | + | 4 |
SEMINAL VESICLE | + | 4 |
AUTOLYSIS | 3 | 1 3.0|
TESTES | + | 4 |
AUTOLYSIS | 4 | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + | 4 |
HYPERPLASIA | 3 | 2 2.5|
LYMPH NODE | + + + | 8 |
LYMPH NODE,MANDIBULAR | + | 3 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 61
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:26.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 7| 2| 2| 2| 3| 3| 3| 3| 3| 3| 6| 6| 7| 7| 2| 2| 2| 3| 3| 3| 3| 3| 3| U V I|
25MG/KG R 2YR 11 11 | 2| 7| 8| 9| 0| 1| 2| 3| 4| 5| 2| 3| 6| 7| 7| 8| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
APOPTOSIS,LYMPHOCYTE | | 1 3.0|
LYMPH NODE,MESENTERIC | + + + | 8 |
APOPTOSIS,LYMPHOCYTE | | 1 4.0|
DEGENERATION | 3 | 1 3.0|
SPLEEN | + + + + + | 8 |
APOPTOSIS,LYMPHOCYTE | | 1 4.0|
HEMATOPOIETIC CELL PROLIFERATION | 4 3 3 | 4 3.2|
THYMUS | M | 2 |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M | 0 |
SKIN | + | 4 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + | 4 |
BONE,FEMUR | + | 4 |
BONE,STERNUM | + | 4 |
SKELETAL MUSCLE | + | 4 |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + | 4 |
BRAIN,CEREBELLUM | + | 4 |
BRAIN,CEREBRUM | + | 4 |
HYDROCEPHALUS | | 1 2.0|
MINERALIZATION,THALAMUS | 2 | 2 2.0|
PERIPHERAL NERVE | + | 4 |
SPINAL CORD | + | 3 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + | 4 |
LUNG | + + | 6 |
NOSE | + | 4 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 62
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:26.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 7| 2| 2| 2| 3| 3| 3| 3| 3| 3| 6| 6| 7| 7| 2| 2| 2| 3| 3| 3| 3| 3| 3| U V I|
25MG/KG R 2YR 11 11 | 2| 7| 8| 9| 0| 1| 2| 3| 4| 5| 2| 3| 6| 7| 7| 8| 9| 0| 1| 2| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM
TRACHEA | + | 4 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EAR | | 1 |
EYE | + | 4 |
HARDERIAN GLAND | + + + + | 8 |
LACRIMAL GLAND | + | 4 |
ZYMBAL'S GLAND | M | 3 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + | 4 |
INFARCT,UNILATERAL | | 1 3.0|
URINARY BLADDER | + | 4 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 63
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:27.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 4| S R R|
| 0| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| U V I|
50 MG/KGR 2YR 12 12 | 6| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 1| 2| 6| 7| 1| 2| 3| 4| 5| 6| 7| 8| 9| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + | |
GALLBLADDER | + | |
INTESTINE LARGE | + | |
INTESTINE LARGE,CECUM | + | |
INTESTINE LARGE,COLON | + | |
INTESTINE LARGE,RECTUM | + | |
INTESTINE SMALL | + | |
INTESTINE SMALL,DUODENUM | + | |
INTESTINE SMALL,ILEUM | + | |
INTESTINE SMALL,JEJUNUM | + | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BASOPHILIC FOCUS | | |
CLEAR CELL FOCUS | X X | |
CYST | X | |
HYPERPLASIA,FOCAL,ITO CELL | | |
PANCREAS | + | |
SALIVARY GLANDS | + | |
STOMACH | + | |
STOMACH,FORESTOMACH | + | |
STOMACH,GLANDULAR | + | |
TONGUE | + | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + | |
HEART | + | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + | |
ADRENAL GLAND,CORTEX | + | |
ADRENAL GLAND,MEDULLA | + | |
ISLETS, PANCREATIC | + | |
PARATHYROID GLAND | M | |
PITUITARY GLAND | + | |
THYROID GLAND | M | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 64
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:27.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 4| S R R|
| 0| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| U V I|
50 MG/KGR 2YR 12 12 | 6| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 1| 2| 6| 7| 1| 2| 3| 4| 5| 6| 7| 8| 9| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
COAGULATING GLAND | + | |
EPIDIDYMIS | + | |
PREPUTIAL GLAND | + | |
PROSTATE | + | |
SEMINAL VESICLE | + | |
TESTES | + | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + | |
LYMPH NODE | + | |
LYMPH NODE,MANDIBULAR | + | |
LYMPH NODE,MESENTERIC | + | |
DEGENERATION | | |
SPLEEN | + | |
HEMATOPOIETIC CELL PROLIFERATION | | |
THYMUS | + | |
APOPTOSIS | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M | |
SKIN | + | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + | |
BONE,FEMUR | + | |
BONE,STERNUM | + | |
SKELETAL MUSCLE | + | |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | + | |
BRAIN,CEREBELLUM | + | |
BRAIN,CEREBRUM | + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 65
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:27.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 4| S R R|
| 0| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| U V I|
50 MG/KGR 2YR 12 12 | 6| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 1| 2| 6| 7| 1| 2| 3| 4| 5| 6| 7| 8| 9| 6| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
PERIPHERAL NERVE | + | |
SPINAL CORD | + | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + | |
LUNG | + + | |
HEMORRHAGE,FOCAL,RIGHT,APICAL LOBE,SUBPLEU| | |
RA | | |
NOSE | + | |
TRACHEA | + | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + | |
HARDERIAN GLAND | + | |
LACRIMAL GLAND | + | |
ZYMBAL'S GLAND | + | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + | |
URINARY BLADDER | + | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 66
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:27.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 3| 3| 3| 4| 4| 4| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| U V I|
50 MG/KGR 2YR 12 12 | 7| 8| 9| 0| 1| 2| 3| 4| 5| 4| 5| 8| 9| 6| 7| 8| 9| 0| 1| 2| 3| 4| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | | 1 |
GALLBLADDER | | 1 |
INTESTINE LARGE | | 1 |
INTESTINE LARGE,CECUM | | 1 |
INTESTINE LARGE,COLON | | 1 |
INTESTINE LARGE,RECTUM | | 1 |
INTESTINE SMALL | | 1 |
INTESTINE SMALL,DUODENUM | | 1 |
INTESTINE SMALL,ILEUM | | 1 |
INTESTINE SMALL,JEJUNUM | | 1 |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BASOPHILIC FOCUS | X X | 2 |
CLEAR CELL FOCUS | | 2 |
CYST | | 1 |
HYPERPLASIA,FOCAL,ITO CELL | 3 | 1 3.0|
PANCREAS | | 1 |
SALIVARY GLANDS | | 1 |
STOMACH | | 1 |
STOMACH,FORESTOMACH | | 1 |
STOMACH,GLANDULAR | | 1 |
TONGUE | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | | 1 |
HEART | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | | 1 |
ADRENAL GLAND,CORTEX | | 1 |
ADRENAL GLAND,MEDULLA | | 1 |
ISLETS, PANCREATIC | | 1 |
PARATHYROID GLAND | | 0 |
PITUITARY GLAND | | 1 |
THYROID GLAND | | 0 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 67
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:27.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 3| 3| 3| 4| 4| 4| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| U V I|
50 MG/KGR 2YR 12 12 | 7| 8| 9| 0| 1| 2| 3| 4| 5| 4| 5| 8| 9| 6| 7| 8| 9| 0| 1| 2| 3| 4| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
COAGULATING GLAND | | 1 |
EPIDIDYMIS | | 1 |
PREPUTIAL GLAND | | 1 |
PROSTATE | | 1 |
SEMINAL VESICLE | | 1 |
TESTES | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | | 1 |
LYMPH NODE | + + | 3 |
LYMPH NODE,MANDIBULAR | | 1 |
LYMPH NODE,MESENTERIC | + + | 3 |
DEGENERATION | 3 | 1 3.0|
SPLEEN | + + + | 4 |
HEMATOPOIETIC CELL PROLIFERATION | 3 | 1 3.0|
THYMUS | | 1 |
APOPTOSIS | | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | | 0 |
SKIN | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | | 1 |
BONE,FEMUR | | 1 |
BONE,STERNUM | | 1 |
SKELETAL MUSCLE | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM
BRAIN | | 1 |
BRAIN,CEREBELLUM | | 1 |
BRAIN,CEREBRUM | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 68
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:28.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 3| 3| 3| 4| 4| 4| 4| 4| 4| 6| 6| 7| 7| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| U V I|
50 MG/KGR 2YR 12 12 | 7| 8| 9| 0| 1| 2| 3| 4| 5| 4| 5| 8| 9| 6| 7| 8| 9| 0| 1| 2| 3| 4| 4| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
PERIPHERAL NERVE | | 1 |
SPINAL CORD | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | | 1 |
LUNG | + + + | 5 |
HEMORRHAGE,FOCAL,RIGHT,APICAL LOBE,SUBPLEU| 1 | 1 1.0|
RA | | |
NOSE | | 1 |
TRACHEA | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | | 1 |
HARDERIAN GLAND | + | 2 |
LACRIMAL GLAND | | 1 |
ZYMBAL'S GLAND | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | | 1 |
URINARY BLADDER | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 69
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:39.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 4| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 1| 8| 2| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
| 1| 5| 8| 4| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 0| 2| 6| 7| 4| 4| 4| 4| 4| 4| 4| 5| 6| 6| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| 6| U V I|
100MG/KGR 2YR 13 13 | 4| 1| 1| 7| 3| 4| 5| 6| 7| 8| 9| 0| 3| 4| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 | |
GALLBLADDER | + + A A + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 2 | |
HEMORRHAGE | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
INTESTINE LARGE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
INTESTINE LARGE,CECUM | + + A A + + + + + + + + + + + + + + + + + + + + A | |
AUTOLYSIS | 2 3 | |
INTESTINE LARGE,COLON | + + A + + + + + + + + + + + + + + + + + + + + + A | |
AUTOLYSIS | 2 3 | |
INTESTINE LARGE,RECTUM | + + + A + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 2 | |
INTESTINE SMALL | + + A A + + + + + + + + + + + + + + + + + + + + A | |
INTESTINE SMALL,DUODENUM | + + A A + + + + + + + + + + + + + + + + + + + + A | |
AUTOLYSIS | 2 3 | |
INTESTINE SMALL,ILEUM | + + A A + + + + + + + + + + + + + + + + + + + + A | |
AUTOLYSIS | 2 3 | |
INTESTINE SMALL,JEJUNUM | + + A A + + + + + + + + + + + + + + + + + + + + A | |
AUTOLYSIS | 2 3 | |
LIVER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 2 | |
BASOPHILIC FOCUS | X X | |
CYST | | |
NECROSIS,HEPATOCYTE | 4 | |
THROMBUS | 4 | |
PANCREAS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY,ACINAR CELL | 1 | |
AUTOLYSIS | 2 | |
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 3 | |
AUTOLYSIS | 2 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 2 2| |
STOMACH | + + + + + + + + + + + + + + + + + + + + + + + + + | |
STOMACH,FORESTOMACH | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 70
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:39.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 4| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 1| 8| 2| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
| 1| 5| 8| 4| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 0| 2| 6| 7| 4| 4| 4| 4| 4| 4| 4| 5| 6| 6| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| 6| U V I|
100MG/KGR 2YR 13 13 | 4| 1| 1| 7| 3| 4| 5| 6| 7| 8| 9| 0| 3| 4| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
CYST EPITHELIAL INCLUSION | | |
STOMACH,GLANDULAR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 2 3 | |
HYPERKERATOSIS | | |
HYPERPLASIA | | |
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS,AORTA | 2 | |
HEART | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 2 | |
CARDIOMYOPATHY | | |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + + M + + + + + + + + + + | |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + + M + + + + + + + + + + | |
AUTOLYSIS | 3 2 | |
CYTOPLASMIC ALTERATION | 3 2 | |
HYPERPLASIA | 3 2 2 | |
HYPERPLASIA,SPINDLE CELL | 2 2 2 2 2 2 1 2 | |
ADRENAL GLAND,MEDULLA | + + + + + + + + + + + + + + M + + + + + + + + + + | |
AUTOLYSIS | 3 2 | |
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
PARATHYROID GLAND | + + + + + + + + + + + + + + + + + M + + + + + + + | |
AUTOLYSIS | 3 2 3| |
CYST | X | |
PITUITARY GLAND | M + M + + + M + M + + + + + + + M + + + + M M + M | |
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 3 2 3| |
CYST,FOLLICLE | X | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 71
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:40.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 4| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 1| 8| 2| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
| 1| 5| 8| 4| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 0| 2| 6| 7| 4| 4| 4| 4| 4| 4| 4| 5| 6| 6| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| 6| U V I|
100MG/KGR 2YR 13 13 | 4| 1| 1| 7| 3| 4| 5| 6| 7| 8| 9| 0| 3| 4| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
COAGULATING GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 3 | |
EPIDIDYMIS | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 3 2 | |
GRANULOMA SPERM | 3 | |
INFLAMMATION,CHRONIC | | |
SPERMATOCELE | 2 | |
PREPUTIAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY | 2 3 3 3 3 2 2 3| |
AUTOLYSIS | 3 3 | |
ECTASIA,DUCT | | |
HYPERPLASIA | 2 | |
PROSTATE | + + + + + + + + + + + + + + M + + + + + M + + + + | |
ATROPHY | 2 | |
AUTOLYSIS | 3 2 3| |
INFLAMMATION,ACUTE | 2 | |
SEMINAL VESICLE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 3 2 | |
INFLAMMATION,ACUTE | 3 | |
TESTES | + + + + + + + + + + + + + + + + + + + + + + + + A | |
AUTOLYSIS | 3 3 2 | |
DEGENERATION | 1 | |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 2 | |
HYPERPLASIA | 2 2 | |
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY,LYMPHOCYTE | 2 | |
AUTOLYSIS | 2 | |
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY,LYMPHOCYTE | 2 | |
AUTOLYSIS | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 72
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:40.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 4| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 1| 8| 2| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
| 1| 5| 8| 4| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 0| 2| 6| 7| 4| 4| 4| 4| 4| 4| 4| 5| 6| 6| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| 6| U V I|
100MG/KGR 2YR 13 13 | 4| 1| 1| 7| 3| 4| 5| 6| 7| 8| 9| 0| 3| 4| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
DEGENERATION | | |
HYPERPLASIA | 2 3 3 | |
PIGMENTATION | 3 | |
SPLEEN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ATROPHY,LYMPHOCYTE | 2 | |
AUTOLYSIS | 2 | |
HEMATOPOIETIC CELL PROLIFERATION | 3 | |
HYPERPLASIA,LYMPHOID | 2 | |
THYMUS | + M A M + + M + + + + M M + M + M + + + + + + + + | |
AUTOLYSIS | 2 | |
CYST | X | |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | + M M M M M M M M M M M M M M M M M M M M M M M M | |
AUTOLYSIS | 2 | |
SKIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 2 | |
FIBROUS OSTEODYSTROPHY | 3 | |
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 2 | |
FIBROUS OSTEODYSTROPHY | 2 2 | |
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | | |
POLYARTERITIS | | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 73
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:40.3
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 4| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 1| 8| 2| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
| 1| 5| 8| 4| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 0| 2| 6| 7| 4| 4| 4| 4| 4| 4| 4| 5| 6| 6| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| 6| U V I|
100MG/KGR 2YR 13 13 | 4| 1| 1| 7| 3| 4| 5| 6| 7| 8| 9| 0| 3| 4| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + + + | |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 2 | |
BRAIN,CEREBRUM | M + + + + + + + + + + + + + + + + + + + + + + + + | |
MINERALIZATION,THALAMUS | 2 2 2 1 2 1 2 2 1 2 | |
PERIPHERAL NERVE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 | |
DEGENERATION | | |
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 | |
LUNG | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 2 | |
HYPERPLASIA,ALVEOLAR EPITHELIUM | 1 1 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 3 2 | |
NOSE | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 2 | |
GRANULOMA | | |
TRACHEA | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | A + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | | |
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 2 | |
HYPERPLASIA,UNILATERAL | 3 3 | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | |
LACRIMAL GLAND | + + + + + + + + + + + + + + + + + + + + + + M M + | |
ATROPHY,FOCAL | 2 | |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 74
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:40.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 3| 4| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6|
| 1| 8| 2| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2|
| 1| 5| 8| 4| 1| 1| 1| 1| 1| 1| 1| 1| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 4|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 3| S R R|
| 0| 2| 6| 7| 4| 4| 4| 4| 4| 4| 4| 5| 6| 6| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4| 6| U V I|
100MG/KGR 2YR 13 13 | 4| 1| 1| 7| 3| 4| 5| 6| 7| 8| 9| 0| 3| 4| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 1| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
AUTOLYSIS | 2 | |
ZYMBAL'S GLAND | + + M + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 | |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | + + + + + + + + + + + + + + + + + + + + + + + + + | |
ACCUMULATION HYALINE DROPLET,RENAL TUBULE | | |
AUTOLYSIS | 2 2 | |
DEGENERATION,RENAL TUBULE | 1 1 1 2 | |
GLOMERULOSCLEROSIS | | |
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | |
REGENERATION,RENAL TUBULE | 1 1 1 2 | |
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + + + + + + + | |
AUTOLYSIS | 3 2 3| |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 75
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:50.7
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 8| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 2| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 7| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 8| 8| 4| 4| 4| 4| 4| 5| 5| 5| 5| U V I|
100MG/KGR 2YR 13 13 | 8| 6| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 0| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
ESOPHAGUS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | 4 | 2 3.5|
GALLBLADDER | A + + + + + + + + + + + + + M + + + + + M + + | 43 |
AUTOLYSIS | | 1 2.0|
HEMORRHAGE | | 1 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 2.0|
INTESTINE LARGE | A + + + + + + + + + + + + + + + + + + + + + + | 47 |
INTESTINE LARGE,CECUM | A + + + + + + + + + + + + + + + + + + + + + + | 44 |
AUTOLYSIS | | 2 2.5|
INTESTINE LARGE,COLON | A + + + + + + + + + + + + + + + + + + + + + + | 45 |
AUTOLYSIS | | 2 2.5|
INTESTINE LARGE,RECTUM | A + + + + + + + + + + + + + + + + + + + + + + | 46 |
AUTOLYSIS | | 1 2.0|
INTESTINE SMALL | A + + + + + + + + + + + + + + + + + + + + + + | 44 |
INTESTINE SMALL,DUODENUM | A + + + + + + + + + + + + + + + + + + + + + + | 44 |
AUTOLYSIS | | 2 2.5|
INTESTINE SMALL,ILEUM | A + + + + + + + + + + + + + + + + + + + + + + | 44 |
AUTOLYSIS | | 2 2.5|
INTESTINE SMALL,JEJUNUM | A + + + + + + + + + + + + + + + + + + + + + + | 44 |
AUTOLYSIS | | 2 2.5|
LIVER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 1 2.0|
BASOPHILIC FOCUS | | 2 |
CYST | X | 1 |
NECROSIS,HEPATOCYTE | 3 | 2 3.5|
THROMBUS | | 1 4.0|
PANCREAS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY,ACINAR CELL | | 1 1.0|
AUTOLYSIS | 4 | 2 3.0|
SALIVARY GLANDS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY | | 1 3.0|
AUTOLYSIS | 3 | 2 2.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 2 | 5 2.0|
STOMACH | A + + + + + + + + + + + + + + + + + + + + + + | 47 |
STOMACH,FORESTOMACH | A + + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 76
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:50.9
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 8| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 2| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 7| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 8| 8| 4| 4| 4| 4| 4| 5| 5| 5| 5| U V I|
100MG/KGR 2YR 13 13 | 8| 6| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 0| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
CYST EPITHELIAL INCLUSION | X | 1 |
STOMACH,GLANDULAR | A + + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | | 2 2.5|
HYPERKERATOSIS | 3 | 1 3.0|
HYPERPLASIA | 3 | 1 3.0|
TONGUE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | 4 | 2 3.5|
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM
BLOOD VESSEL | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS,AORTA | | 1 2.0|
HEART | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 1 2.0|
CARDIOMYOPATHY | 1 1 | 2 1.0|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM
ADRENAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
ADRENAL GLAND,CORTEX | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 3 | 3 2.6|
CYTOPLASMIC ALTERATION | 1 2 | 4 2.0|
HYPERPLASIA | | 3 2.3|
HYPERPLASIA,SPINDLE CELL | 2 2 2 2 1 2 3 2 1 2 1 1 1 3 2 2 | 24 1.8|
ADRENAL GLAND,MEDULLA | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 3 | 3 2.6|
ISLETS, PANCREATIC | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
PARATHYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 4 | 4 3.0|
CYST | | 1 |
PITUITARY GLAND | M + + + + + + + + + + + + + + + + M + + + + + | 38 |
THYROID GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | 4 | 5 3.0|
CYST,FOLLICLE | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 77
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:51.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 8| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 2| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 7| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 8| 8| 4| 4| 4| 4| 4| 5| 5| 5| 5| U V I|
100MG/KGR 2YR 13 13 | 8| 6| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 0| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM
COAGULATING GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | 3 | 3 3.0|
EPIDIDYMIS | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | 3 | 4 2.7|
GRANULOMA SPERM | | 1 3.0|
INFLAMMATION,CHRONIC | 3 | 1 3.0|
SPERMATOCELE | | 1 2.0|
PREPUTIAL GLAND | + + + + M + + + + + + + + + + + + + + + + + + | 47 |
ATROPHY | 2 2 2 2 3 | 13 2.4|
AUTOLYSIS | 3 | 3 3.0|
ECTASIA,DUCT | 3 | 1 3.0|
HYPERPLASIA | | 1 2.0|
PROSTATE | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
ATROPHY | | 1 2.0|
AUTOLYSIS | 4 | 4 3.0|
INFLAMMATION,ACUTE | | 1 2.0|
SEMINAL VESICLE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | 3 | 4 2.7|
INFLAMMATION,ACUTE | | 1 3.0|
TESTES | A + + + + + + + + + + + + + + + + + + + + + + | 46 |
AUTOLYSIS | | 3 2.6|
DEGENERATION | | 1 1.0|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM
BONE MARROW | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 1 2.0|
HYPERPLASIA | | 2 2.0|
LYMPH NODE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
LYMPH NODE,MANDIBULAR | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY,LYMPHOCYTE | | 1 2.0|
AUTOLYSIS | 3 | 2 2.5|
LYMPH NODE,MESENTERIC | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY,LYMPHOCYTE | | 1 2.0|
AUTOLYSIS | 3 | 2 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 78
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:51.2
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 8| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 2| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 7| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 8| 8| 4| 4| 4| 4| 4| 5| 5| 5| 5| U V I|
100MG/KGR 2YR 13 13 | 8| 6| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 0| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM
DEGENERATION | 3 1 3 | 3 2.3|
HYPERPLASIA | | 3 2.6|
PIGMENTATION | | 1 3.0|
SPLEEN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
ATROPHY,LYMPHOCYTE | 2 | 2 2.0|
AUTOLYSIS | 4 | 2 3.0|
HEMATOPOIETIC CELL PROLIFERATION | 4 3 3 3 3 | 6 3.1|
HYPERPLASIA,LYMPHOID | | 1 2.0|
THYMUS | + M M + M + + M + M M M M + + + M + + + + M + | 30 |
AUTOLYSIS | | 1 2.0|
CYST | | 1 |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
MAMMARY GLAND | M M M M M M M M M M M + M M M M M M M M M M M | 2 |
AUTOLYSIS | | 1 2.0|
SKIN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM
BONE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BONE,FEMUR | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 1 2.0|
FIBROUS OSTEODYSTROPHY | | 1 3.0|
BONE,STERNUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 1 2.0|
FIBROUS OSTEODYSTROPHY | | 2 2.0|
SKELETAL MUSCLE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | 4 | 2 3.5|
INFILTRATION CELLULAR,LYMPHOCYTIC | 1 | 1 1.0|
POLYARTERITIS | 3 | 1 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 79
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:51.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 8| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 2| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 7| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 8| 8| 4| 4| 4| 4| 4| 5| 5| 5| 5| U V I|
100MG/KGR 2YR 13 13 | 8| 6| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 0| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM
BRAIN | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
BRAIN,CEREBELLUM | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 1 2.0|
BRAIN,CEREBRUM | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
MINERALIZATION,THALAMUS | 2 2 2 2 2 1 2 2 2 | 19 1.7|
PERIPHERAL NERVE | + + + + + + + + + + + + + + + M + + + + + + + | 47 |
AUTOLYSIS | 4 | 2 3.5|
DEGENERATION | 2 | 1 2.0|
SPINAL CORD | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM
LARYNX | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | 4 | 2 3.5|
LUNG | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 1 2.0|
HYPERPLASIA,ALVEOLAR EPITHELIUM | 2 2 2 | 5 1.6|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 2 2.5|
NOSE | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | | 1 2.0|
GRANULOMA | X | 1 |
TRACHEA | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | 4 | 2 3.5|
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM
EYE | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 4 | 1 4.0|
HARDERIAN GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | 4 | 3 3.0|
HYPERPLASIA,UNILATERAL | | 2 3.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | 2 | 2 1.5|
LACRIMAL GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 46 |
ATROPHY,FOCAL | | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 80
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:51.5
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 3| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
| 8| 2| 2| 2| 2| 2| 2| 2| 2| 2| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 2| 3| 3|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| S R R|
| 7| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 8| 8| 4| 4| 4| 4| 4| 5| 5| 5| 5| U V I|
100MG/KGR 2YR 13 13 | 8| 6| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 0| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM
AUTOLYSIS | 3 | 2 2.5|
ZYMBAL'S GLAND | + + + + + + + + + + + + + + + + + + + + + + + | 47 |
AUTOLYSIS | 4 | 2 3.5|
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM
KIDNEY | A + + + + + + + + + + + + + + + + + + + + + + | 47 |
ACCUMULATION HYALINE DROPLET,RENAL TUBULE | 4 3 | 2 3.5|
AUTOLYSIS | | 2 2.0|
DEGENERATION,RENAL TUBULE | | 4 1.2|
GLOMERULOSCLEROSIS | 2 2 2 | 3 2.0|
INFILTRATION CELLULAR,LYMPHOCYTIC | | 1 2.0|
REGENERATION,RENAL TUBULE | | 4 1.2|
URINARY BLADDER | + + + + + + + + + + + + + + + + + + + + + + + | 48 |
AUTOLYSIS | 4 | 4 3.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 81
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:52.0
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
| 3| 3| 3| 5| 5| 5| 3| 3| 3| 5| 5| 5|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| S R R|
| 2| 2| 2| 4| 4| 4| 2| 2| 2| 4| 4| 4| U V I|
CONTROL R 64W 14 14 | 2| 3| 4| 6| 7| 8| 3| 4| 5| 7| 8| 9| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
LIVER | + + + + + + + + + + + + | 12 |
FATTY CHANGE,PERIPHERAL | 2 | 1 2.0|
VACUOLIZATION CYTOPLASMIC,CENTRILOBULAR | 2 | 1 2.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 82
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:52.4
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
| 3| 3| 3| 5| 5| 5| 3| 3| 3| 5| 5| 5|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| S R R|
| 2| 2| 2| 4| 5| 5| 2| 2| 2| 5| 5| 5| U V I|
25 MG/KGR 64W 15 15 | 5| 6| 7| 9| 0| 1| 6| 7| 8| 0| 1| 2| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
LIVER | + + + + + + + + + + + + | 12 |
FATTY CHANGE,PERIPHERAL | 2 3 | 2 2.5|
GRANULOMA,MULTIPLE | X | 1 |
VACUOLIZATION CYTOPLASMIC,CENTRILOBULAR | 1 2 | 2 1.5|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 83
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:52.8
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
| 3| 3| 3| 5| 5| 5| 3| 3| 3| 5| 5| 5|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| S R R|
| 2| 2| 3| 5| 5| 5| 2| 3| 3| 5| 5| 5| U V I|
50 MG/KGR 64W 16 16 | 8| 9| 0| 2| 3| 4| 9| 0| 1| 3| 4| 5| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
LIVER | + + + + + + + + + + + + | 12 |
FATTY CHANGE,PERIPHERAL | 1 2 | 2 1.5|
VACUOLIZATION CYTOPLASMIC,CENTRILOBULAR | 2 2 | 2 2.0|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM
SKIN | + | 1 |
ATROPHY,FOCAL,HAIR FOLLICLE | 4 | 1 4.0|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED
NCTR EXP/TEST: 211701 PAGE: 84
INDIVIDUAL ANIMAL NON-TUMOR PATHOLOGY TABLE DATE: 02/15/2000
PATHOLOGY REPORT 4 TIME: 14:31:53.1
------------------------------------------------------------------------------------------------------------------------------------
DAYS ON | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
TEST | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|
| 3| 3| 3| 5| 5| 5| 3| 3| 3| 5| 5| 5|
------------------------------------------------------------------------------------------------------------------------ O S|
------------------------------------------------------------------------------------------------------------------------ T B E|
| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| I S V|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| S E V|
MALE CARCASS ID | 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| S R R|
| 3| 3| 3| 5| 5| 5| 3| 3| 3| 5| 5| 5| U V I|
100MG/KGR 64W 17 17 | 1| 2| 3| 5| 6| 7| 2| 3| 4| 6| 7| 8| E E T|
------------------------------------------------------------------------------------------------------------------------ S D Y|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM
LIVER | + + + + + + + + + + + + | 12 |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY M : MISSING TISSUE 1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED A : AUTOLYSIS PRECLUDES EXAMINATION 1) MINIMAL 3) MODERATE
I : INSUFFICIENT TISSUE BLANK : NOT EXAMINED 2) MILD 4)MARKED