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TDMS Study 97013-09 Pathology Tables

NTP  EXP/TEST: 97013-09                    WATER DISINFECTION MODEL (SODIUM BROMATE)                              PAGE: 1
TEST TYPE: SUBCHRON 26-WEEK                     INITIAL AND CURRENT BODY WEIGHT                                   DATE: 06/18/04
ROUTE: DOSED WATER                                                                                                TIME: 11:03:20

                                                         EIS REPORT 03


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  97013A

       CONTRACT NUMBER:  N01-ES-65406

       CAS NUMBER:  7789-38-0

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 97013-09                    WATER DISINFECTION MODEL (SODIUM BROMATE)                              PAGE: 2
TEST TYPE: SUBCHRON 26-WEEK                     INITIAL AND CURRENT BODY WEIGHT                                   DATE: 06/18/04
ROUTE: DOSED WATER                                          EISRPT03                                              TIME: 11:03:20
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 SPECIES-STRAIN: TG.AC HEMI-MICE            SEX: FEMALE      WEEK ON DOSE: 27     FIRST DOSE: 09/28/99
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             15     19.2    0.7        10     31.3    5.5                     10     12.1    5.3

 80 MG/L            15     19.4    0.9         9     30.5    4.5        97.4          9     11.1    4.6

 400 MG/L           15     19.7    0.5        10     32.5    3.5       103.8         10     13.0    3.7

 800 MG/L           15     19.8    0.8        12     26.5    4.1        84.6         12      6.8    3.9

 TPA                15     18.3    1.1         3     29.9    3.4        95.5          3     11.7    3.9




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 SPECIES-STRAIN: TG.AC HEMI-MICE            SEX: MALE        WEEK ON DOSE: 27     FIRST DOSE: 09/28/99
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             15     23.6    0.7        13     38.0    4.7                     13     14.4    4.6

 80 MG/L            15     23.9    0.9        13     38.0    3.0       100.0         13     14.0    2.9

 400 MG/L           15     23.6    0.7        14     34.0    4.4        89.4         14     10.5    4.5

 800 MG/L           15     23.8    1.1        14     32.1    3.2        84.4         14      8.3    3.0

 TPA                15     21.8    1.0         3     30.1    2.2        79.2          3      8.9    3.0

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