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TDMS Study 97013-10 Pathology Tables

NTP  EXP/TEST: 97013-10                    WATER DISINFECTION MODEL (SODIUM BROMATE)                              PAGE: 1
TEST TYPE: SUBCHRON 26-WEEK                     INITIAL AND CURRENT BODY WEIGHT                                   DATE: 06/18/04
ROUTE: DOSED WATER                                                                                                TIME: 08:48:30

                                                         EIS REPORT 03


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  97013A

       CONTRACT NUMBER:  N01-ES-65406

       CAS NUMBER:  7789-38-0

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 97013-10                    WATER DISINFECTION MODEL (SODIUM BROMATE)                              PAGE: 2
TEST TYPE: SUBCHRON 26-WEEK                     INITIAL AND CURRENT BODY WEIGHT                                   DATE: 06/18/04
ROUTE: DOSED WATER                                          EISRPT03                                              TIME: 08:48:30
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 SPECIES-STRAIN: P53(C57BL/6)-MICE          SEX: FEMALE      WEEK ON DOSE: 27     FIRST DOSE: 09/29/99
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             15     20.1    0.9        14     34.3    7.4                     14     14.4    7.0

 80 MG/L            15     19.9    1.0        15     33.7    6.8        98.2         15     13.8    6.0

 400 MG/L           15     19.6    1.0        15     33.2    7.5        96.7         15     13.5    6.8

 800 MG/L           15     19.9    1.0        14     30.3    4.4        88.3         14     10.4    4.7




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 SPECIES-STRAIN: P53(C57BL/6)-MICE          SEX: MALE        WEEK ON DOSE: 27     FIRST DOSE: 09/29/99
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             15     24.2    1.5        14     46.5    4.9                     14     22.5    4.2

 80 MG/L            15     24.8    1.4        14     48.1    2.5       103.4         14     23.4    2.3

 400 MG/L           15     24.8    1.1        14     47.2    3.7       101.5         14     22.5    3.3

 800 MG/L           15     24.6    1.2        14     45.5    4.1        97.8         14     21.0    3.8

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