National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/15946

TDMS Study 97013-11 Pathology Tables

NTP  EXP/TEST: 97013-11                    WATER DISINFECTION MODEL (SODIUM BROMATE)                              PAGE: 1
TEST TYPE: SUBCHRON 26-WEEK                     INITIAL AND CURRENT BODY WEIGHT                                   DATE: 06/18/04
ROUTE: SKIN APPLICATION                                                                                           TIME: 08:54:22

                                                         EIS REPORT 03


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  97013B

       CONTRACT NUMBER:  N01-ES-65406

       CAS NUMBER:  7789-38-0

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 97013-11                    WATER DISINFECTION MODEL (SODIUM BROMATE)                              PAGE: 2
TEST TYPE: SUBCHRON 26-WEEK                     INITIAL AND CURRENT BODY WEIGHT                                   DATE: 06/18/04
ROUTE: SKIN APPLICATION                                     EISRPT03                                              TIME: 08:54:22
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 SPECIES-STRAIN: TG.AC HEMI-MICE            SEX: FEMALE      WEEK ON DOSE: 26     FIRST DOSE: 10/29/99
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/KG            15     19.4    1.4        11     27.1    5.5                     11      7.6    4.6

 64 MG/KG           15     19.4    1.4        10     27.6    3.2       101.8         10      8.4    2.4

 128     MG/KG      15     19.5    1.1        11     25.7    3.5        94.8         11      6.3    3.7

 256     MG/KG      15     19.3    1.2        11     28.2    3.3       104.0         11      8.6    2.7

 TPA                15     19.6    1.0         0      0.0    0.0                      0      0.0    0.0




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 SPECIES-STRAIN: TG.AC HEMI-MICE            SEX: MALE        WEEK ON DOSE: 26     FIRST DOSE: 10/29/99
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/KG            15     24.2    2.2        12     34.5    6.2                     12     10.2    4.0

 64 MG/KG           15     23.4    2.0        11     34.2    3.4        99.1         11     10.5    2.9

 128     MG/KG      15     24.2    1.7        13     34.6    3.7       100.2         13     10.5    2.9

 256     MG/KG      15     23.8    1.8        15     30.5    3.5        88.4         15      6.7    3.2

 TPA                15     24.6    1.7         0      0.0    0.0                      0      0.0    0.0

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