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TDMS Study 97013-14 Pathology Tables

NTP  EXP/TEST: 97013-14                  WATER DISINFECTION MODEL (DICHLOROACETIC ACID)                           PAGE: 1
TEST TYPE: SUBCHRON 26-WEEK                     INITIAL AND CURRENT BODY WEIGHT                                   DATE: 01/27/05
ROUTE: DOSED WATER                                                                                                TIME: 09:11:06

                                                         EIS REPORT 03


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  97013C

       CONTRACT NUMBER:  N01-ES-65406

       CAS NUMBER:  79-43-6

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 97013-14                  WATER DISINFECTION MODEL (DICHLOROACETIC ACID)                           PAGE: 2
TEST TYPE: SUBCHRON 26-WEEK                     INITIAL AND CURRENT BODY WEIGHT                                   DATE: 01/27/05
ROUTE: DOSED WATER                                          EISRPT03                                              TIME: 09:11:06
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 SPECIES-STRAIN: P53(C57BL/6)-MICE          SEX: FEMALE      WEEK ON DOSE: 26     FIRST DOSE: 01/18/00
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             15     18.7    0.9        15     30.0    4.9                     15     11.3    4.5

 500 MG/L           15     18.6    0.8        15     28.5    4.1        95.0         15      9.9    3.8

 1000MG/L           15     18.8    1.0        14     24.9    1.8        83.0         14      6.1    1.7

 2000MG/L           15     18.4    1.2        14     24.7    1.3        82.3         14      6.4    1.6




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 SPECIES-STRAIN: P53(C57BL/6)-MICE          SEX: MALE        WEEK ON DOSE: 26     FIRST DOSE: 01/18/00
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             15     23.1    0.9        15     46.9    2.4                     15     23.9    2.4

 500 MG/L           15     23.1    1.1        15     44.6    4.6        95.0         15     21.5    3.9

 1000MG/L           15     22.7    1.3        15     36.6    6.0        78.0         15     13.9    5.4

 2000MG/L           15     22.9    0.9        15     32.3    3.5        68.8         15      9.3    3.4

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