National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/11603

TDMS Study 97013-93 Pathology Tables

                                                                                                                                   
NTP                             FEED, WATER, AND COMPOUND CONSUMPTION TABLE                                       REPORT: EISRPT39  
LAB: Battelle Columbus                      WATER DISINFECTION MODEL (SODIUM BROMATE)                               DATE: 12/08/03  
EXPERIMENT: 97013 TEST: 93                                                                                        TIME: 14:19:10    
                                                CAGES FROM 0000 TO LAST CAGE                                      PAGE:    1        
TEST TYPE: 26-39 WEEKS                              ROUTE: DOSED WATER                                            NTP:  C97013H     
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               REASONS FOR REMOVAL:    ALL                                                                                          
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
               REMOVAL DATE RANGE:     ALL                                                                                          
                                                                                                                                    
               TREATMENT GROUPS:       INCLUDE ALL                                                                                  
                                                                                                                                   
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
NTP                                         FEED, WATER, AND COMPOUND CONSUMPTION TABLE                           REPORT: EISRPT39  
LAB: BATTELLE COLUMBUS                                WATER DISINFECTION MODEL (SODIUM BROMATE)                   DATE: 12/08/03    
EXPERIMENT: 97013 TEST: 93                                                                                        TIME: 14:24:40    
                                                                                                                                    
                                                                                                                                    
TEST TYPE: 26                                       ROUTE: DOSED WATER                                            NTP:  97013H      
CONT: N01-ES-65406                                                                                                CAS: 7789-38-0    
                                                                                                                                   
                                          WATER AND COMPOUND CONSUMPTION BY MALE MICE IN THE                                        
                                   26 DOSED WATER STUDY OF WATER DISINFECTION MODEL (SODIUM BROMATE)                                
==================================================================================================================================  
           0 MG/L                     80 MG/L                            400 MG/L                           800 MG/L                
     ----------------    ---------------------------------  ---------------------------------  ---------------------------------    
                                          DOSE/                              DOSE/                              DOSE/               
      GRAMS    BODY      GRAMS    BODY    CONTROL           GRAMS    BODY    CONTROL           GRAMS    BODY    CONTROL             
      WATER/   WEIGHT    WATER/   WEIGHT  WATER (B)  DOSE/  WATER/   WEIGHT  WATER (B)  DOSE/  WATER/   WEIGHT  WATER (B)  DOSE/    
WEEK  DAY(A)  (GRAMS)    DAY(A)  (GRAMS)  (GRAMS)   DAY(C)  DAY(A)  (GRAMS)  (GRAMS)   DAY(C)  DAY(A)  (GRAMS)  (GRAMS)   DAY(C)    
==================================================================================================================================  
  2     3.5    25.6       3.4     25.4    0.97     10.8      3.5     25.9    1.00     53.4      3.2     24.5    0.91    103.4       
  3     3.4    27.2       3.8     26.8    1.12     11.4      3.5     27.3    1.03     50.9      3.2     26.2    0.94     98.4       
  5     3.5    29.2       3.6     28.7    1.03     10.0      3.5     29.5    1.00     46.8      3.4     28.5    0.97     94.5       
  6     3.4    30.8       3.5     29.8    1.03      9.3      3.4     30.7    1.00     44.5      3.3     29.8    0.97     87.2       
  7     3.6    32.7       3.8     31.8    1.06      9.5      3.5     32.7    0.97     43.0      3.4     31.8    0.94     86.4       
  8     3.5    33.7       3.5     33.0    1.00      8.6      3.5     33.9    1.00     41.6      3.2     32.8    0.91     78.0       
  9     3.5    34.7       3.6     33.8    1.03      8.5      3.4     33.3    0.97     40.3      3.2     33.6    0.91     76.6       
 10     3.5    35.9       3.6     35.3    1.03      8.2      3.5     35.0    1.00     40.5      3.2     34.6    0.91     74.6       
 11     3.4    37.2       3.6     36.7    1.06      7.9      3.5     36.7    1.03     38.7      3.0     35.2    0.88     69.2       
 12     3.3    38.6       3.5     36.7    1.06      7.7      3.3     37.5    1.00     35.7      3.1     36.2    0.94     69.5       
 13     3.5    39.9       4.2     38.6    1.20      8.6      3.8     39.0    1.09     38.5      3.2     37.3    0.91     69.0       
 14     3.3    40.6       3.8     40.0    1.15      7.6      3.5     40.0    1.06     35.3      3.1     38.3    0.94     65.6       
 15     3.5    42.0       3.9     41.1    1.11      7.6      3.4     41.0    0.97     33.6      3.2     39.5    0.91     65.4       
 16     3.6    42.5       3.9     42.0    1.08      7.5      3.6     41.7    1.00     34.9      3.4     40.0    0.94     68.9       
 17     3.8    43.6       3.9     42.8    1.03      7.4      3.7     42.4    0.97     34.8      3.4     40.5    0.89     67.1       
 18     3.6    44.3       4.2     44.0    1.17      7.6      3.8     43.0    1.06     35.0      3.5     41.3    0.97     68.4       
 19     3.7    45.3       4.1     44.8    1.11      7.4      3.9     43.9    1.05     35.5      3.4     42.2    0.92     64.9       
 20     3.6    45.8       3.9     45.1    1.08      6.9      3.9     44.3    1.08     34.9      3.4     43.0    0.94     62.9       
 21     3.5    46.3       3.9     45.8    1.11      6.7      3.9     44.9    1.11     34.6      3.3     43.7    0.94     61.0       
 22     3.5    46.7       4.1     46.3    1.17      7.1      3.9     45.3    1.11     34.1      3.3     44.1    0.94     59.4       
 23     3.4    46.8       3.8     45.9    1.12      6.6      4.0     46.0    1.18     34.4      3.3     44.8    0.97     58.5       
 25     1.8    47.5       2.0     47.7    1.11      3.3      2.0     47.3    1.11     16.8      1.5     46.4    0.83     26.1       
 26     3.6    48.4       3.6     47.3    1.00      6.0      4.1     48.0    1.14     34.0      3.3     47.2    0.92     55.8       
 27     3.7    48.1       4.0     48.1    1.08      6.7      4.1     47.8    1.11     34.0      3.2     46.7    0.86     54.3       
 28     3.9    49.5       3.9     49.3    1.00      6.4      4.4     48.9    1.13     36.1      3.6     47.6    0.92     60.5       
 29     3.6    49.3       3.7     49.0    1.03      6.1      3.9     48.9    1.08     32.2      3.4     47.9    0.94     56.3       
 30     3.6    49.5       4.0     48.4    1.11      6.6      4.1     49.0    1.14     33.8      3.5     48.2    0.97     58.9       
 31     3.6    49.8       3.7     47.7    1.03      6.2      4.1     49.5    1.14     33.0      3.5     48.7    0.97     57.2       
 32     3.9    50.1       3.8     49.8    0.97      6.2      4.2     48.8    1.08     34.2      3.4     47.2    0.87     57.9       
 33     3.6    50.4       3.8     50.2    1.06      6.0      4.1     49.6    1.14     33.3      3.4     48.6    0.94     56.2       
 34     3.5    50.1       3.8     50.5    1.09      6.1      4.0     48.9    1.14     33.1      3.2     48.5    0.91     52.9       
 35     3.5    49.2       3.7     50.4    1.06      5.9      4.2     49.5    1.20     34.2      3.2     48.9    0.91     51.9       
 36     3.8    49.6       4.0     50.8    1.05      6.4      4.2     50.1    1.11     33.5      3.2     49.5    0.84     51.8       
 37     4.0    50.4       3.9     50.6    0.98      6.2      4.2     50.3    1.05     33.6      3.4     50.2    0.85     54.6       
 38     3.9    50.2       4.1     51.3    1.05      6.4      4.2     50.8    1.08     33.2      3.4     50.5    0.87     53.7       
 39     3.9    50.2       4.1     51.4    1.05      6.3      4.1     51.0    1.05     32.4      3.3     50.5    0.85     52.1       
 40     4.0    50.0       4.2     52.1    1.05      6.4      4.3     51.5    1.08     33.5      3.5     51.2    0.88     54.0       
 41     4.3    51.8       4.2     52.6    0.98      6.4      4.5     50.8    1.05     35.6      3.5     51.7    0.81     53.9       
 42     4.1    51.4       4.3     52.5    1.05      6.5      4.7     50.9    1.15     37.2      3.4     51.2    0.83     53.2       
1 TO 13 WEEKS                                                                                                                       
----------------                                                                                                                    
MEAN    3.5    33.2       3.6     32.4    1.05      9.1      3.5     32.9    1.01     43.1      3.2     31.9    0.93     82.4       
SD(D)   0.1               0.2             0.06      1.2      0.1             0.03      5.4      0.1             0.03     12.3       
CV(E)   2.0               5.6             5.8      13.1      3.2             3.1      12.6      3.2             2.9      14.9       
14 TO 52 WEEKS                                                                                                                      
----------------                                                                                                                    
MEAN    3.6    47.8       3.9     47.8    1.07      6.5      4.0     47.3    1.09     33.6      3.3     46.4    0.91     57.3       
SD(D)   0.4               0.4             0.06      0.8      0.5             0.06      3.5      0.4             0.05      8.1       
CV(E)  11.8              10.7             5.2      12.8     12.1             5.1      10.3     11.2             5.3      14.1       
==================================================================================================================================  
(A) GRAMS OF WATER CONSUMED PER ANIMAL PER DAY.                                                                                     
(B) GRAMS OF WATER PER DAY FOR THE DOSED GROUP DIVIDED BY THAT FOR THE CONTROLS.                                                    
                                                                                                                                   
(C) MILLIGRAMS OF COMPOUND CONSUMED PER DAY PER KILOGRAM BODY WEIGHT.                                                               
(D) STANDARD DEVIATION OF WEEKLY MEAN.                                                                                              
(E) COEFFICIENT OF VARIATION = (STANDARD DEVIATION / MEAN) X 100.                                                                   
                                                                                                                                   
                                          WATER AND COMPOUND CONSUMPTION BY FEMALE MICE IN THE                                      
                                   26 DOSED WATER STUDY OF WATER DISINFECTION MODEL (SODIUM BROMATE)                                
==================================================================================================================================  
           0 MG/L                     80 MG/L                            400 MG/L                           800 MG/L                
     ----------------    ---------------------------------  ---------------------------------  ---------------------------------    
                                           DOSE/                              DOSE/                              DOSE/              
      GRAMS    BODY      GRAMS    BODY    CONTROL           GRAMS    BODY    CONTROL           GRAMS    BODY    CONTROL             
      WATER/   WEIGHT    WATER/   WEIGHT  WATER (B)  DOSE/  WATER/   WEIGHT  WATER (B)  DOSE/  WATER/   WEIGHT  WATER (B)  DOSE/    
WEEK  DAY(A)  (GRAMS)    DAY(A)  (GRAMS)  (GRAMS)   DAY(C)  DAY(A)  (GRAMS)  (GRAMS)   DAY(C)  DAY(A)  (GRAMS)  (GRAMS)   DAY(C)    
==================================================================================================================================  
  2     3.7    20.5       3.8     20.4     1.03    15.0      3.7     20.0     1.00    73.9      3.6     19.8     0.97   145.2       
  3     4.5    21.2       4.2     21.6     0.93    15.6      4.0     20.7     0.89    77.4      3.7     21.1     0.82   138.9       
  5     4.8    22.1       4.2     23.0     0.88    14.5      4.0     22.0     0.83    72.3      4.2     22.3     0.88   149.9       
  6     4.4    22.5       3.8     23.4     0.86    13.0      4.0     22.0     0.91    71.9      4.2     22.2     0.95   149.7       
  7     4.4    23.1       4.3     23.9     0.98    14.3      3.9     22.4     0.89    69.1      4.0     23.0     0.91   138.5       
  8     4.8    23.6       4.0     24.0     0.83    13.3      3.9     22.5     0.81    69.1      4.3     23.2     0.90   147.2       
  9     4.2    23.4       4.0     24.4     0.95    13.1      4.0     22.7     0.95    71.4      4.4     23.4     1.05   149.4       
 10     4.5    24.2       4.2     24.6     0.93    13.7      4.2     23.3     0.93    71.9      4.1     23.9     0.91   135.7       
 11     4.1    24.9       4.2     25.3     1.02    13.2      4.1     23.4     1.00    69.6      4.1     24.5     1.00   135.4       
 12     4.1    25.7       4.2     25.9     1.02    12.9      4.0     23.8     0.98    66.6      3.8     24.7     0.93   122.2       
 13     4.6    26.4       4.2     27.0     0.91    12.4      4.3     24.7     0.93    69.5      4.3     25.4     0.93   135.1       
 14     4.8    27.0       4.2     27.3     0.88    12.2      4.1     24.4     0.85    67.7      4.1     25.6     0.85   127.1       
 15     4.8    27.6       4.6     27.7     0.96    13.3      4.2     24.6     0.88    69.2      4.4     26.1     0.92   133.4       
 16     4.8    28.8       4.5     28.5     0.94    12.6      4.2     25.3     0.88    65.9      4.0     26.9     0.83   118.5       
 17     4.9    29.7       4.3     29.3     0.88    11.7      4.4     25.7     0.90    68.1      4.1     27.3     0.84   121.4       
 18     5.0    30.5       4.6     30.4     0.92    12.1      4.2     26.5     0.84    63.7      4.4     28.3     0.88   123.3       
 19     5.1    31.1       4.3     31.5     0.84    10.8      4.3     27.1     0.84    64.2      4.1     28.7     0.80   115.0       
 20     4.6    31.7       4.7     32.5     1.02    11.5      4.3     27.5     0.93    62.1      4.0     28.6     0.87   112.0       
 21     4.8    32.5       4.4     33.0     0.92    10.7      4.5     28.5     0.94    63.7      4.1     29.3     0.85   112.5       
 22     4.7    33.2       4.3     33.4     0.91    10.3      4.3     28.3     0.91    60.2      4.1     29.9     0.87   110.1       
 23     4.5    33.8       4.0     33.3     0.89     9.6      4.1     29.3     0.91    56.1      3.8     30.9     0.84    98.6       
 25     2.3    35.9       2.1     35.3     0.91     4.8      2.0     30.3     0.87    26.4      1.8     32.0     0.78    44.2       
 26     4.7    36.6       4.6     35.4     0.98    10.5      4.1     31.5     0.87    51.6      3.9     33.1     0.83    93.2       
 27     4.8    37.1       4.6     37.0     0.96     9.9      4.2     31.9     0.88    52.6      4.0     33.6     0.83    94.0       
 28     4.7    38.9       4.6     38.6     0.98     9.4      4.5     33.4     0.96    54.2      4.0     35.0     0.85    91.0       
 29     4.7    38.5       4.4     38.8     0.94     9.1      4.1     33.5     0.87    48.9      3.8     35.3     0.81    86.8       
 30     4.8    39.0       4.6     39.5     0.96     9.2      4.1     33.1     0.85    50.0      4.0     36.1     0.83    87.7       
 31     4.6    39.8       4.6     40.2     1.00     9.1      4.1     33.5     0.89    48.3      3.6     36.8     0.78    78.5       
 32     5.2    40.7       4.7     40.5     0.90     9.2      4.5     34.9     0.87    51.3      3.8     37.0     0.73    82.9       
 33     4.5    41.3       4.4     41.1     0.98     8.6      4.0     35.3     0.89    45.7      3.4     36.2     0.76    74.1       
 34     4.4    42.2       4.7     42.2     1.07     8.9      3.9     35.0     0.89    44.3      3.6     37.6     0.82    76.6       
 35     4.2    42.4       4.4     42.7     1.05     8.3      4.1     35.9     0.98    46.1      3.5     38.0     0.83    73.8       
 36     4.4    43.4       4.2     43.5     0.95     7.7      4.2     36.8     0.95    45.8      3.8     39.0     0.86    78.7       
 37     5.2    44.5       4.6     44.5     0.88     8.2      4.1     37.9     0.79    43.0      3.6     39.5     0.69    73.8       
 38     4.4    45.2       4.9     44.0     1.11     8.8      4.1     37.6     0.93    43.9      3.7     40.5     0.84    73.5       
 39     4.4    44.6       4.7     44.3     1.07     8.4      4.3     37.9     0.98    45.2      3.6     40.8     0.82    70.2       
 40     4.7    44.1       4.7     44.4     1.00     8.4      4.7     38.9     1.00    48.1      3.8     41.5     0.81    73.0       
 41     4.5    45.0       4.7     46.1     1.04     8.1      4.2     38.9     0.93    43.6      3.7     42.2     0.82    69.4       
 42     4.6    47.4       4.5     46.1     0.98     7.9      4.3     38.6     0.93    45.1      3.5     42.1     0.76    66.3       
1 TO 13 WEEKS                                                                                                                       
----------------                                                                                                                    
MEAN    4.4    23.4       4.1     24.0     0.94    13.7      4.0     22.5     0.92    71.1      4.0     23.0     0.93   140.7       
SD(D)   0.3               0.2              0.07     1.0      0.2              0.06     2.9      0.3              0.06     8.6       
CV(E)   7.5               4.1              7.2      7.2      4.0              6.8      4.1      6.5              6.6      6.1       
14 TO 52 WEEKS                                                                                                                      
----------------                                                                                                                    
MEAN    4.6    37.6       4.4     37.5     0.96     9.6      4.1     32.2     0.90    52.7      3.8     34.2     0.82    91.4       
SD(D)   0.5               0.5              0.07     1.8      0.5              0.05    10.1      0.5              0.05    22.4       
CV(E)  11.1              11.0              6.9     18.8     11.0              5.4     19.2     12.4              5.8     24.5       
==================================================================================================================================  
(A) GRAMS OF WATER CONSUMED PER ANIMAL PER DAY.                                                                                     
(B) GRAMS OF WATER PER DAY FOR THE DOSED GROUP DIVIDED BY THAT FOR THE CONTROLS.                                                    
                                                                                                                                   
(C) MILLIGRAMS OF COMPOUND CONSUMED PER DAY PER KILOGRAM BODY WEIGHT.                                                               
(D) STANDARD DEVIATION OF WEEKLY MEAN.                                                                                              
(E) COEFFICIENT OF VARIATION = (STANDARD DEVIATION / MEAN) X 100.                                                                   
                                                                                                                                   
                      DIAGNOSTIC TRAILER REPORT                                                                                     
                      WATER AND COMPOUND CONSUMPTION BY MALE MICE IN THE                                                            
                      26 DOSED WATER STUDY OF WATER DISINFECTION MODEL (SODIUM BROMATE)                                             
=========================================================================================================                           
           0 MG/L                  80 MG/L                  400 MG/L                 800 MG/L                                       
     ----------------------   ----------------------   ----------------------   ----------------------                              
     DAILY WATER  BODY  NUM   DAILY WATER  BODY  NUM   DAILY WATER  BODY  NUM   DAILY WATER  BODY  NUM                              
WEEK WATER HOURS   WGT  WGTS  WATER HOURS   WGT  WGTS  WATER HOURS   WGT  WGTS  WATER HOURS   WGT  WGTS                             
==========================================================================================================                          
  B               24.8  10                 24.6  10                 25.2  10                 24.7  10                               
  1               24.8  10                 24.6  10                 25.2  10                 24.7  10                               
  2   3.5  1675   25.6  10     3.4  1680   25.4  10     3.5  1507   25.9  10     3.2  1674   24.5  10                               
  3   3.4  2854   27.2  10     3.8  2687   26.8  10     3.5  2850   27.3  10     3.2  2860   26.2  10                               
  4   3.5   460   28.1  10     3.7   455   27.5  10     3.7   460   28.4  10     3.5   462   27.3  10                               
  5   3.5  1685   29.2  10     3.6  1680   28.7  10     3.5  1680   29.5  10     3.4  1680   28.5  10                               
  6   3.4  1690   30.8  10     3.5  1695   29.8  10     3.4  1695   30.7  10     3.3  1690   29.8  10                               
  7   3.6  1670   32.7  10     3.8  1540   31.8  10     3.5  1670   32.7  10     3.4  1670   31.8  10                               
  8   3.5  1685   33.7  10     3.5  1680   33.0  10     3.5  1685   33.9  10     3.2  1685   32.8  10                               
  9   3.5  1727   34.7  10     3.6  1740   33.8  10     3.4  1551   33.3  10     3.2  1725   33.6  10                               
 10   3.5  1665   35.9  10     3.6  1666   35.3  10     3.5  1670   35.0  10     3.2  1673   34.6  10                               
 11   3.4  1680   37.2  10     3.6  1675   36.7  10     3.5  1685   36.7  10     3.0  1681   35.2  10                               
 12   3.3  1679   38.6  10     3.5  1516   36.7  10     3.3  1388   37.5  10     3.1  1427   36.2  10                               
 13   3.5  1671   39.9  10     4.2  1670   38.6  10     3.8  1671   39.0  10     3.2  1671   37.3  10                               
 14   3.3  1700   40.6  10     3.8  1695   40.0  10     3.5  1695   40.0  10     3.1  1700   38.3  10                               
 15   3.5  2113   42.0  10     3.9  1995   41.1  10     3.4  2165   41.0  10     3.2  2160   39.5  10                               
 16   3.6  1200   42.5  10     3.9  1210   42.0  10     3.6  1200   41.7  10     3.4  1200   40.0  10                               
 17   3.8  1680   43.6  10     3.9  1680   42.8  10     3.7  1512   42.4  10     3.4  1680   40.5  10                               
 18   3.6  1670   44.3  10     4.2  1670   44.0  10     3.8  1670   43.0  10     3.5  1670   41.3  10                               
 19   3.7  1655   45.3  10     4.1  1650   44.8  10     3.9  1655   43.9  10     3.4  1655   42.2  10                               
 20   3.6  1680   45.8  10     3.9  1680   45.1  10     3.9  1680   44.3  10     3.4  1680   43.0  10                               
 21   3.5  1686   46.3  10     3.9  1681   45.8  10     3.9  1518   44.9  10     3.3  1680   43.7  10                               
 22   3.5  1680   46.7  10     4.1  1680   46.3  10     3.9  1680   45.3  10     3.3  1680   44.1  10                               
 23   3.4  1720   46.8  10     3.8  1728   45.9  10     4.0  1721   46.0  10     3.3  1720   44.8  10                               
 25   1.8  3345   47.5  10     2.0  3341   47.7  10     2.0  3344   47.3  10     1.5  3350   46.4  10                               
 26   3.6  1665   48.4  10     3.6   951   47.3  10     4.1  1614   48.0  10     3.3  1665   47.2  10                               
 27   3.7  2200   48.1  10     4.0  2096   48.1  10     4.1  2173   47.8  10     3.2  1929   46.7  10                               
 28   3.9  1135   49.5  10     3.9  1112   49.3  10     4.4   908   48.9  10     3.6  1135   47.6  10                               
 29   3.6  1691   49.3  10     3.7  1695   49.0  10     3.9  1691   48.9  10     3.4  1690   47.9  10                               
 30   3.6  1690   49.5  10     4.0  1520   48.4  10     4.1  1690   49.0  10     3.5  1666   48.2  10                               
 31   3.6  1683   49.8  10     3.7  1690   47.7  10     4.1  1680   49.5  10     3.5  1680   48.7  10                               
 32   3.9  1683   50.1  10     3.8  1670   49.8   9     4.2  1680   48.8  10     3.4  1513   47.2  10                               
 33   3.6  1674   50.4  10     3.8  1508   50.2   9     4.1  1676   49.6  10     3.4  1508   48.6   9                               
 34   3.5  1710   50.1  10     3.8  1530   50.5   9     4.0  1534   48.9  10     3.2  1534   48.5   9                               
 35   3.5  1648   49.2  10     3.7  1494   50.4   9     4.2  1668   49.5  10     3.2  1461   48.9   9                               
 36   3.8  1675   49.6  10     4.0  1508   50.8   9     4.2  1503   50.1   9     3.2  1391   49.5   9                               
 37   4.0  1670   50.4  10     3.9  1503   50.6   9     4.2  1503   50.3   9     3.4  1503   50.2   9                               
 38   3.9  1680   50.2  10     4.1  1344   51.3   8     4.2  1512   50.8   9     3.4  1512   50.5   9                               
 39   3.9  1700   50.2  10     4.1  1360   51.4   8     4.1  1530   51.0   9     3.3  1530   50.5   9                               
 40   4.0  1670   50.0  10     4.2  1289   52.1   8     4.3  1503   51.5   9     3.5  1503   51.2   9                               
 41   4.3  1504   51.8   9     4.2  1328   52.6   8     4.5  1336   50.8   9     3.5  1502   51.7   9                               
 42   4.1  1515   51.4   9     4.3  1360   52.5   8     4.7  1352   50.9   8     3.4  1518   51.2   9                               
MEAN BODY WGT FOR WEEKS                                                                                                             
1 TO 13           32.2                     31.4                     31.9                     31.0                                   
14 TO 52          47.8                     47.8                     47.3                     46.4                                   
=========================================================================================================                           
    (B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.                                                                              
                                                                                                                                   
                      DIAGNOSTIC TRAILER REPORT                                                                                     
                      WATER AND COMPOUND CONSUMPTION BY FEMALE MICE IN THE                                                          
                      26 DOSED WATER STUDY OF WATER DISINFECTION MODEL (SODIUM BROMATE)                                             
=========================================================================================================                           
           0 MG/L                  80 MG/L                  400 MG/L                 800 MG/L                                       
     ----------------------   ----------------------   ----------------------   ----------------------                              
     DAILY WATER  BODY  NUM   DAILY WATER  BODY  NUM   DAILY WATER  BODY  NUM   DAILY WATER  BODY  NUM                              
WEEK WATER HOURS   WGT  WGTS  WATER HOURS   WGT  WGTS  WATER HOURS   WGT  WGTS  WATER HOURS   WGT  WGTS                             
==========================================================================================================                          
  B               19.6  10                 20.0  10                 19.7  10                 19.8  10                               
  1               19.6  10                 20.0  10                 19.7  10                 19.8  10                               
  2   3.7  1670   20.5  10     3.8  1606   20.4  10     3.7  1675   20.0  10     3.6  1621   19.8  10                               
  3   4.5  2570   21.2  10     4.2  2850   21.6  10     4.0  2848   20.7  10     3.7  2855   21.1  10                               
  4   4.5   423   21.9  10     4.4   405   22.2  10     3.9   415   21.6  10     3.6   470   21.4  10                               
  5   4.8  1348   22.1  10     4.2  1512   23.0  10     4.0  1680   22.0  10     4.2  1680   22.3  10                               
  6   4.4  1352   22.5  10     3.8  1357   23.4  10     4.0  1695   22.0  10     4.2  1692   22.2  10                               
  7   4.4  1545   23.1  10     4.3  1665   23.9  10     3.9  1665   22.4  10     4.0  1670   23.0  10                               
  8   4.8  1521   23.6  10     4.0  1344   24.0  10     3.9  1685   22.5  10     4.3  1690   23.2  10                               
  9   4.2  1368   23.4  10     4.0  1564   24.4  10     4.0  1725   22.7  10     4.4  1710   23.4  10                               
 10   4.5  1503   24.2  10     4.2  1503   24.6  10     4.2  1670   23.3  10     4.1  1675   23.9  10                               
 11   4.1  1256   24.9  10     4.2  1508   25.3  10     4.1  1517   23.4  10     4.1  1690   24.5  10                               
 12   4.1  1165   25.7  10     4.2  1486   25.9  10     4.0  1385   23.8  10     3.8  1499   24.7  10                               
 13   4.6  1504   26.4  10     4.2  1503   27.0  10     4.3  1670   24.7  10     4.3  1671   25.4  10                               
 14   4.8  1705   27.0  10     4.2  1526   27.3  10     4.1  1627   24.4  10     4.1  1705   25.6  10                               
 15   4.8  1781   27.6  10     4.6  2108   27.7  10     4.2  1996   24.6  10     4.4  2165   26.1  10                               
 16   4.8   952   28.8  10     4.5  1089   28.5  10     4.2  1200   25.3  10     4.0  1190   26.9  10                               
 17   4.9  1680   29.7  10     4.3  1344   29.3  10     4.4  1680   25.7  10     4.1  1680   27.3  10                               
 18   5.0  1670   30.5  10     4.6  1503   30.4  10     4.2  1551   26.5  10     4.4  1670   28.3  10                               
 19   5.1  1660   31.1  10     4.3  1320   31.5  10     4.3  1655   27.1  10     4.1  1660   28.7  10                               
 20   4.6  1362   31.7  10     4.7  1512   32.5  10     4.3  1680   27.5  10     4.0  1680   28.6  10                               
 21   4.8  1690   32.5  10     4.4  1387   33.0  10     4.5  1686   28.5  10     4.1  1686   29.3  10                               
 22   4.7  1554   33.2  10     4.3  1553   33.4  10     4.3  1678   28.3  10     4.1  1680   29.9  10                               
 23   4.5  1710   33.8  10     4.0  1730   33.3  10     4.1  1722   29.3  10     3.8  1710   30.9  10                               
 25   2.3  3351   35.9  10     2.1  3006   35.3  10     2.0  3345   30.3  10     1.8  3353   32.0  10                               
 26   4.7  1516   36.6  10     4.6  1002   35.4  10     4.1  1614   31.5  10     3.9  1609   33.1  10                               
 27   4.8  1936   37.1  10     4.6  2024   37.0  10     4.2  2053   31.9  10     4.0  2035   33.6  10                               
 28   4.7  1008   38.9  10     4.6  1087   38.6  10     4.5  1048   33.4  10     4.0  1061   35.0  10                               
 29   4.7  1521   38.5  10     4.4  1695   38.8  10     4.1  1525   33.5  10     3.8  1690   35.3  10                               
 30   4.8  1279   39.0  10     4.6  1395   39.5  10     4.1  1248   33.1  10     4.0  1690   36.1  10                               
 31   4.6  1556   39.8  10     4.6  1521   40.2  10     4.1  1680   33.5  10     3.6  1670   36.8  10                               
 32   5.2  1636   40.7  10     4.7  1670   40.5  10     4.5  1632   34.9  10     3.8  1690   37.0  10                               
 33   4.5  1512   41.3  10     4.4  1672   41.1  10     4.0  1507   35.3  10     3.4  1512   36.2  10                               
 34   4.4  1710   42.2  10     4.7  1700   42.2  10     3.9  1715   35.0  10     3.6  1720   37.6  10                               
 35   4.2  1473   42.4  10     4.4  1655   42.7  10     4.1  1643   35.9  10     3.5  1511   38.0  10                               
 36   4.4  1503   43.4  10     4.2  1558   43.5  10     4.2  1409   36.8  10     3.8  1553   39.0  10                               
 37   5.2  1503   44.5  10     4.6  1503   44.5  10     4.1  1503   37.9  10     3.6  1670   39.5  10                               
 38   4.4  1680   45.2  10     4.9  1512   44.0  10     4.1  1581   37.6  10     3.7  1680   40.5  10                               
 39   4.4  1190   44.6  10     4.7  1671   44.3  10     4.3  1700   37.9  10     3.6  1700   40.8  10                               
 40   4.7  1503   44.1  10     4.7  1670   44.4  10     4.7  1670   38.9  10     3.8  1503   41.5  10                               
 41   4.5  1344   45.0  10     4.7  1328   46.1   9     4.2  1358   38.9  10     3.7  1680   42.2  10                               
 42   4.6  1295   47.4   9     4.5  1408   46.1   9     4.3  1542   38.6  10     3.5  1675   42.1  10                               
MEAN BODY WGT FOR WEEKS                                                                                                             
1 TO 13           23.0                     23.5                     22.2                     22.7                                   
14 TO 52          37.6                     37.5                     32.2                     34.2                                   
=========================================================================================================                           
    (B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.                                                                              
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.