National Toxicology Program

National Toxicology Program
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TDMS Study 97013-95 Pathology Tables

NTP  EXP/TEST: 97013-95                 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE)                           PAGE: 1
TEST TYPE: 26-39 WEEKS                          INITIAL AND CURRENT BODY WEIGHT                                   DATE: 10/08/03
ROUTE: DOSED WATER                                                                                                TIME: 10:05:47

                                                         EIS REPORT 03
                                                           FINAL/MICE


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  97013J

       CONTRACT NUMBER:  NO1-ES-65406

       CAS NUMBER:  75-27-4

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 97013-95                 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE)                           PAGE: 2
TEST TYPE: 26-39 WEEKS                          INITIAL AND CURRENT BODY WEIGHT                                   DATE: 10/08/03
ROUTE: DOSED WATER                                          EISRPT03                                              TIME: 10:05:47
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 SPECIES-STRAIN: TG.AC HEMI-MICE            SEX: FEMALE      WEEK ON DOSE: 43     FIRST DOSE: 08/30/99
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             10     19.2    0.9         5     35.7    4.7                      5     16.3    4.2

 175 MG/L           10     19.1    1.0         8     35.8    8.1       100.2          8     16.8    7.7

 350 MG/L           10     18.9    1.0         4     42.8   11.4       119.8          4     24.2   10.8

 700 MG/L           10     19.3    0.5         4     39.3    7.4       110.0          4     20.0    7.1




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 SPECIES-STRAIN: TG.AC HEMI-MICE            SEX: MALE        WEEK ON DOSE: 43     FIRST DOSE: 08/30/99
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             10     22.4    1.5         6     42.4    3.3                      6     20.5    3.2

 175 MG/L           10     22.7    0.8         9     41.8    7.6        98.5          9     19.1    7.2

 350 MG/L           10     23.2    1.0         8     39.1    4.2        92.2          8     15.6    4.8

 700 MG/L           10     22.8    1.1         9     38.3    5.4        90.3          9     15.6    4.5

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