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TDMS Study 96018-04 Pathology Tables

NTP  EXP/TEST: 96018-04               WATER DISINFECTION BYPRODUCTS (BROMODICHLOROMETHANE)                        PAGE: 1
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 03/25/03
ROUTE: DOSED WATER                                                                                                TIME: 11:02:32

                                                         EIS REPORT 03
                                                         FINAL #1/MICE


       FACILITY:  Southern Research Institute

       NTP C#:  C96018

       CONTRACT NUMBER:  N01-ES-85420

       CAS NUMBER:  75-27-4

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 96018-04               WATER DISINFECTION BYPRODUCTS (BROMODICHLOROMETHANE)                        PAGE: 2
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 03/25/03
ROUTE: DOSED WATER                                          EISRPT03                                              TIME: 11:02:32
----------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: B6C3F1-MICE                SEX: FEMALE      WEEK ON DOSE: 105    FIRST DOSE: 12/15/98
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             50     18.6    0.8        36     57.1    8.7                     36     38.6    8.6

 175 MG/L           50     18.4    0.8        36     53.8    9.8        94.2         36     35.4    9.9

 350 MG/L           50     18.6    0.9        33     51.8    7.2        90.7         33     33.2    7.0

 700 MG/L           50     18.5    0.8        39     55.3    6.5        96.8         39     36.7    6.7

                                               -----------------------------------
                                               ---------- END-OF-REPORT ----------
                                               -----------------------------------