National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/16575

TDMS Study 89029-02 Pathology Tables

NTP Experiment-Test: 89029-02         INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a)               Report: PEIRPT03
Study Type: SUBCHRON 8-WEEK                               MAGNETIC FIELDS (EMF)                                   Date: 10/25/04
Route: MAGNETIC FIELDS                                                                                            Time: 11:33:57




       Facility:  I. I. T. Research Institute

       Chemical CAS #:  ELECTROMAG

       Lock Date:  02/15/94

       Cage Range:  All

       Reasons For Removal:    All

       Removal Date Range:     All

       Treatment Groups:       Include All




































a  Number of animals examined microscopically at site and number of animals with lesion

                                                              Page   1


NTP Experiment-Test: 89029-02         INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a)               Report: PEIRPT03  
Study Type: SUBCHRON 8-WEEK                               MAGNETIC FIELDS (EMF)                                   Date: 10/25/04    
Route: MAGNETIC FIELDS                                                                                            Time: 11:33:57    
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         B6C3F1 MICE FEMALE                        UNTREAT.     .02          2            10           10 GAUSS                     
                                                   CONTROL      GAUSS        GAUSS        GAUSS        INTER                        
____________________________________________________________________________________________________________________________________
                                                                                                                                    
DISPOSITION SUMMARY                                                                                                                 
                                                                                                                                    
  Animals Initially In Study                          10           10           10           10           10                        
  Early Deaths                                                                                                                      
  Survivors                                                                                                                         
    Terminal Sacrifice                                10           10           10           10           10                        
                                                                                                                                    
  Animals Examined Microscopically                    10           10           10           10           10                        
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 ALIMENTARY SYSTEM                                                                                                                  
                                                                                                                                    
   Liver                                              (10)         (10)         (10)         (10)         (10)                      
      Hepatocyte, Necrosis                             1 (10%)      1 (10%)                                                         
   Pancreas                                           (10)         (10)         (10)         (10)         (10)                      
      Vacuolization Cytoplasmic                        1 (10%)                                1 (10%)                               
   Salivary Glands                                    (10)         (10)         (10)         (10)         (10)                      
      Infiltration Cellular                            1 (10%)                                                                      
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 CARDIOVASCULAR SYSTEM                                                                                                              
                                                                                                                                    
   Heart                                              (10)         (10)         (10)         (10)         (10)                      
      Myocardium, Mineralization                                                 1 (10%)                                            
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 ENDOCRINE SYSTEM                                                                                                                   
                                                                                                                                    
   Pituitary Gland                                    (10)         (9)          (10)         (10)         (10)                      
      Pars Distalis, Cyst                                                                     1 (10%)                               
   Thyroid Gland                                      (9)          (8)          (10)         (10)         (10)                      
      Infiltration Cellular                            1 (11%)                                                                      
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 GENERAL BODY SYSTEM                                                                                                                
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 GENITAL SYSTEM                                                                                                                     
                                                                                                                                    
   Uterus                                             (10)         (10)         (10)         (10)         (10)                      
      Hydrometra                                                                 1 (10%)                                            
____________________________________________________________________________________________________________________________________
                                                                                                                                    
a  Number of animals examined microscopically at site and number of animals with lesion                                             
                                                                                                                                    
                                                             Page    2                                                              
                                                                                                                                   
NTP Experiment-Test: 89029-02         INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a)               Report: PEIRPT03  
Study Type: SUBCHRON 8-WEEK                               MAGNETIC FIELDS (EMF)                                   Date: 10/25/04    
Route: MAGNETIC FIELDS                                                                                            Time: 11:33:57    
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         B6C3F1 MICE FEMALE                        UNTREAT.     .02          2            10           10 GAUSS                     
                                                   CONTROL      GAUSS        GAUSS        GAUSS        INTER                        
____________________________________________________________________________________________________________________________________
                                                                                                                                    
                                                                                                                                    
 HEMATOPOIETIC SYSTEM                                                                                                               
                                                                                                                                    
   Lymph Node, Mandibular                             (10)         (10)         (10)         (10)         (9)                       
      Congestion                                       1 (10%)                                                                      
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 INTEGUMENTARY SYSTEM                                                                                                               
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 MUSCULOSKELETAL SYSTEM                                                                                                             
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 NERVOUS SYSTEM                                                                                                                     
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 RESPIRATORY SYSTEM                                                                                                                 
                                                                                                                                    
   Lung                                               (10)         (10)         (10)         (10)         (10)                      
      Hemorrhage                                                                              1 (10%)                               
      Inflammation, Chronic Active                     1 (10%)                   1 (10%)                                            
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 SPECIAL SENSES SYSTEM                                                                                                              
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 URINARY SYSTEM                                                                                                                     
                                                                                                                                    
   Urinary Bladder                                    (10)         (8)          (9)          (10)         (10)                      
      Infiltration Cellular                            1 (10%)                                                                      
                                                                                                                                    
                                                                                                                                    
a  Number of animals examined microscopically at site and number of animals with lesion                                             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page    3                                                              
                                                                                                                                   
NTP Experiment-Test: 89029-02         INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a)               Report: PEIRPT03  
Study Type: SUBCHRON 8-WEEK                               MAGNETIC FIELDS (EMF)                                   Date: 10/25/04    
Route: MAGNETIC FIELDS                                                                                            Time: 11:33:57    
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         B6C3F1 MICE MALE                          UNTREAT.     .02          2            10           10 GAUSS                     
                                                   CONTROL      GAUSS        GAUSS        GAUSS        INTER                        
____________________________________________________________________________________________________________________________________
                                                                                                                                    
DISPOSITION SUMMARY                                                                                                                 
                                                                                                                                    
  Animals Initially In Study                          10           10           10           10           10                        
  Early Deaths                                                                                                                      
  Survivors                                                                                                                         
    Terminal Sacrifice                                10           10           10           10           10                        
                                                                                                                                    
  Animals Examined Microscopically                    10           10           10           10           10                        
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 ALIMENTARY SYSTEM                                                                                                                  
                                                                                                                                    
   Liver                                              (10)         (10)         (10)         (10)         (10)                      
      Hepatocyte, Necrosis                                          1 (10%)      1 (10%)      1 (10%)                               
   Salivary Glands                                    (10)         (10)         (10)         (10)         (10)                      
      Infiltration Cellular                                                                   1 (10%)                               
   Stomach, Glandular                                 (10)         (10)         (10)         (10)         (10)                      
      Infiltration Cellular                                                      1 (10%)                                            
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 CARDIOVASCULAR SYSTEM                                                                                                              
                                                                                                                                    
   Heart                                              (10)         (10)         (10)         (10)         (10)                      
      Mineralization                                                                          1 (10%)                               
      Myocardium, Infiltration Cellular                                          1 (10%)                                            
      Myocardium, Mineralization                       1 (10%)                                1 (10%)      1 (10%)                  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 ENDOCRINE SYSTEM                                                                                                                   
                                                                                                                                    
   Parathyroid Gland                                  (10)         (9)          (6)          (8)          (3)                       
      Cyst                                                          1 (11%)                                                         
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 GENERAL BODY SYSTEM                                                                                                                
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 GENITAL SYSTEM                                                                                                                     
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
a  Number of animals examined microscopically at site and number of animals with lesion                                             
                                                                                                                                    
                                                                                                                                    
                                                             Page    4                                                              
                                                                                                                                   
NTP Experiment-Test: 89029-02         INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a)               Report: PEIRPT03  
Study Type: SUBCHRON 8-WEEK                               MAGNETIC FIELDS (EMF)                                   Date: 10/25/04    
Route: MAGNETIC FIELDS                                                                                            Time: 11:33:57    
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         B6C3F1 MICE MALE                          UNTREAT.     .02          2            10           10 GAUSS                     
                                                   CONTROL      GAUSS        GAUSS        GAUSS        INTER                        
____________________________________________________________________________________________________________________________________
                                                                                                                                    
                                                                                                                                    
 HEMATOPOIETIC SYSTEM                                                                                                               
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 INTEGUMENTARY SYSTEM                                                                                                               
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 MUSCULOSKELETAL SYSTEM                                                                                                             
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 NERVOUS SYSTEM                                                                                                                     
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 RESPIRATORY SYSTEM                                                                                                                 
                                                                                                                                    
   Lung                                               (10)         (10)         (10)         (10)         (10)                      
      Inflammation, Chronic Active                                                                         1 (10%)                  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 SPECIAL SENSES SYSTEM                                                                                                              
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 URINARY SYSTEM                                                                                                                     
                                                                                                                                    
   Urinary Bladder                                    (10)         (10)         (10)         (10)         (10)                      
      Calculus Micro Observation Only                                                         1 (10%)                               
                                                                                                                                    
                                                                                                                                    
a  Number of animals examined microscopically at site and number of animals with lesion                                             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page    5                                                              
                                                                                                                                   
                             ------------------------------------------------------------                                           
                             ----------              END OF REPORT             ----------                                           
                             ------------------------------------------------------------                                           
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.