National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/19863

TDMS Study 88138-04 Pathology Tables

NTP  EXP/TEST: 88138-04                                   BENZOPHENONE                                            PAGE: 1
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 06/24/03
ROUTE: DOSED FEED                                                                                                 TIME: 08:52:48

                                                         EIS REPORT 03
                                                          FINAL#1/MICE


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  88138B

       CONTRACT NUMBER:  N01-ES-55388

       CAS NUMBER:  119-61-9

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 88138-04                                   BENZOPHENONE                                            PAGE: 2
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 06/24/03
ROUTE: DOSED FEED                                           EISRPT03                                              TIME: 08:52:48
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 SPECIES-STRAIN: B6C3F1-MICE                SEX: FEMALE      WEEK ON DOSE: 105    FIRST DOSE: 09/13/99
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 PPM              50     18.8    1.0        40     44.0    6.0                     40     25.4    5.7

 312 PPM            50     18.6    0.9        42     40.7    6.5        92.5         42     22.1    6.2

 625 PPM            50     18.6    0.9        41     40.3    5.9        91.5         41     21.7    6.0

 1250 PPM           50     18.5    1.2        31     38.1    6.2        86.5         31     19.7    5.6




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 SPECIES-STRAIN: B6C3F1-MICE                SEX: MALE        WEEK ON DOSE: 105    FIRST DOSE: 09/14/99
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 PPM              50     23.3    1.4        44     40.3    6.7                     44     16.9    6.3

 312 PPM            50     23.1    1.4        44     39.5    7.4        98.0         44     16.4    7.2

 625 PPM            50     22.9    1.2        44     40.4    6.2       100.2         44     17.5    5.9

 1250 PPM           50     23.3    1.4        45     38.4    5.1        95.2         45     15.3    5.0

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