TDMS Study 93027-11 Pathology Tables
NTP Experiment-Test: 93027-11 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: SUBCHRON 90-DAY PEROXISOME PROJECT (DIBUTYL PHTHALATE) Date: 07/08/99
Route: DOSED FEED Time: 09:48:44
13 WEEK SUBCHRONIC
Facility: Battelle Columbus Laboratory
Chemical CAS #: 84-74-2
Lock Date: 06/12/96
Cage Range: All
Reasons For Removal: All
Removal Date Range: All
Treatment Groups: Include All
a Number of animals examined microscopically at site and number of animals with lesion
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NTP Experiment-Test: 93027-11 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: SUBCHRON 90-DAY PEROXISOME PROJECT (DIBUTYL PHTHALATE) Date: 07/08/99
Route: DOSED FEED Time: 09:48:44
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SPRAGUE-DAWLEY RATS MALE 0 PPM 1000 2500 5000 10,000 20,000
PPM PPM PPM PPM PPM
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DISPOSITION SUMMARY
Animals Initially in Study 10 10 10 10 10 10
Early Deaths
Survivors
Terminal Sacrifice 10 10 10 10 10 10
Animals Examined Microscopically 10 10 10 10 10 10
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ALIMENTARY SYSTEM
None
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CARDIOVASCULAR SYSTEM
None
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ENDOCRINE SYSTEM
None
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GENERAL BODY SYSTEM
None
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GENITAL SYSTEM
None
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HEMATOPOIETIC SYSTEM
None
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INTEGUMENTARY SYSTEM
None
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NTP Experiment-Test: 93027-11 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: SUBCHRON 90-DAY PEROXISOME PROJECT (DIBUTYL PHTHALATE) Date: 07/08/99
Route: DOSED FEED Time: 09:48:44
____________________________________________________________________________________________________________________________________
SPRAGUE-DAWLEY RATS MALE 0 PPM 1000 2500 5000 10,000 20,000
PPM PPM PPM PPM PPM
____________________________________________________________________________________________________________________________________
MUSCULOSKELETAL SYSTEM
None
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NERVOUS SYSTEM
None
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RESPIRATORY SYSTEM
None
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SPECIAL SENSES SYSTEM
None
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URINARY SYSTEM
Kidney (10) (10) (10) (10) (10) (10)
Renal Tubule, Carcinoma 1 (10%)
NTP Experiment-Test: 93027-11 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: SUBCHRON 90-DAY PEROXISOME PROJECT (DIBUTYL PHTHALATE) Date: 07/08/99
Route: DOSED FEED Time: 09:48:44
____________________________________________________________________________________________________________________________________
SPRAGUE-DAWLEY RATS MALE 0 PPM 1000 2500 5000 10,000 20,000
PPM PPM PPM PPM PPM
____________________________________________________________________________________________________________________________________
TUMOR SUMMARY
Total Animals with Primary Neoplasms (b) 1
Total Primary Neoplasms 1
Total Animals with Benign Neoplasms
Total Benign Neoplasms
Total Animals with Malignant Neoplasms 1
Total Malignant Neoplasms 1
Total Animals with Metastatic Neoplasms
Total Metastatic Neoplasm
Total Animals with Malignant Neoplasms
Uncertain Primary Site
Total Animals with Neoplasms Uncertain-
Benign or Malignant
Total Uncertain Neoplasms
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a Number of animals examined microscopically at site and number of animals with lesion
b Primary tumors: all tumors except metastatic tumors
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