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TDMS Study 97013-15 Pathology Tables

NTP  EXP/TEST: 97013-15                  WATER DISINFECTION MODEL (DICHLOROACETIC ACID)                           PAGE: 1
TEST TYPE: SUBCHRON 26-WEEK                     INITIAL AND CURRENT BODY WEIGHT                                   DATE: 01/27/05
ROUTE: SKIN APPLICATION                                                                                           TIME: 09:15:02

                                                         EIS REPORT 03


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  97013D

       CONTRACT NUMBER:  N01-ES-65406

       CAS NUMBER:  79-43-6

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 97013-15                  WATER DISINFECTION MODEL (DICHLOROACETIC ACID)                           PAGE: 2
TEST TYPE: SUBCHRON 26-WEEK                     INITIAL AND CURRENT BODY WEIGHT                                   DATE: 01/27/05
ROUTE: SKIN APPLICATION                                     EISRPT03                                              TIME: 09:15:02
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 SPECIES-STRAIN: TG.AC HEMI-MICE            SEX: FEMALE      WEEK ON DOSE: 27     FIRST DOSE: 02/17/00
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/KG            15     19.6    1.3        11     24.7    3.9                     11      5.2    4.1

 31.25   MG/KG      15     19.3    1.3        12     26.7    3.2       108.0         12      7.4    2.5

 125MG/KG           15     19.3    1.3        14     27.0    5.1       109.3         14      7.8    4.4

 TPA                15     18.3    1.9         0      0.0    0.0                      0      0.0    0.0

 500MG/KG           15     19.0    1.0        15     27.0    1.4       109.3         15      8.0    1.0




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 SPECIES-STRAIN: TG.AC HEMI-MICE            SEX: MALE        WEEK ON DOSE: 27     FIRST DOSE: 02/17/00
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/KG            15     22.4    1.1        13     33.3    3.2                     13     10.9    3.3

 31.25   MG/KG      15     22.6    1.4        14     32.9    2.7        98.7         14     10.1    2.8

 125MG/KG           15     22.9    1.2        14     33.1    2.6        99.3         14     10.1    2.2

 TPA                15     21.6    2.0         0      0.0    0.0                      0      0.0    0.0

 500MG/KG           15     22.5    1.1        12     32.1    3.9        96.3         12      9.4    3.9

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