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TDMS Study 97013-05 Pathology Tables

NTP  EXP/TEST: 97013-05                 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE)                           PAGE: 1
TEST TYPE: SUBCHRON 26-WEEK                     INITIAL AND CURRENT BODY WEIGHT                                   DATE: 06/11/04
ROUTE: DOSED WATER                                                                                                TIME: 08:06:35

                                                         EIS REPORT 03


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  97013E

       CONTRACT NUMBER:  NO1-ES-65406

       CAS NUMBER:  75-27-4

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 97013-05                 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE)                           PAGE: 2
TEST TYPE: SUBCHRON 26-WEEK                     INITIAL AND CURRENT BODY WEIGHT                                   DATE: 06/11/04
ROUTE: DOSED WATER                                          EISRPT03                                              TIME: 08:06:35
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 SPECIES-STRAIN: TG.AC HEMI-MICE            SEX: FEMALE      WEEK ON DOSE: 27     FIRST DOSE: 08/30/99
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             15     19.2    0.7        10     29.9    4.0                     10     10.9    4.0

 175 MG/L           15     19.1    0.6        13     34.9    4.9       116.7         13     15.7    4.6

 350 MG/L           15     19.0    0.7        11     33.9    7.5       113.3         11     14.8    7.4

 700 MG/L           15     18.9    1.0        13     33.2    5.1       111.0         13     14.1    4.9

 TPA                15     18.4    1.3         0      0.0    0.0                      0      0.0    0.0




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 SPECIES-STRAIN: TG.AC HEMI-MICE            SEX: MALE        WEEK ON DOSE: 27     FIRST DOSE: 08/30/99
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             15     23.1    0.9        13     41.0    4.3                     13     18.1    3.9

 175 MG/L           15     22.6    1.4        12     40.4    4.6        98.5         12     17.8    4.2

 350 MG/L           15     22.6    0.8        12     38.3    3.4        93.4         12     15.9    3.5

 700 MG/L           15     22.7    1.0        14     36.5    3.5        89.0         14     13.8    3.4

 TPA                15     21.4    1.3         0      0.0    0.0                      0      0.0    0.0

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