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TDMS Study 97013-90 Pathology Tables

NTP  EXP/TEST: 97013-90                  WATER DISINFECTION MODEL (DICHLOROACETIC ACID)                           PAGE: 1
TEST TYPE: 26-39 WEEKS                          INITIAL AND CURRENT BODY WEIGHT                                   DATE: 12/05/03
ROUTE: DOSED WATER                                                                                                TIME: 09:16:27

                                                         EIS REPORT 03


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  97013I

       CONTRACT NUMBER:  N01-ES-65406

       CAS NUMBER:  79-43-6

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 97013-90                  WATER DISINFECTION MODEL (DICHLOROACETIC ACID)                           PAGE: 2
TEST TYPE: 26-39 WEEKS                          INITIAL AND CURRENT BODY WEIGHT                                   DATE: 12/05/03
ROUTE: DOSED WATER                                          EISRPT03                                              TIME: 09:16:27
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 SPECIES-STRAIN: P53(C57BL/6)-MICE          SEX: FEMALE      WEEK ON DOSE: 41     FIRST DOSE: 01/18/00
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             10     18.6    0.8        10     43.3    7.6                     10     24.7    7.3

 500 MG/L           10     18.6    0.7         9     37.7    8.6        87.0          9     19.2    8.9

 1000MG/L           10     18.7    1.1        10     27.1    2.4        62.5         10      8.5    2.0

 2000MG/L           10     18.9    1.0         9     26.1    1.9        60.2          9      7.2    1.8




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 SPECIES-STRAIN: P53(C57BL/6)-MICE          SEX: MALE        WEEK ON DOSE: 41     FIRST DOSE: 01/18/00
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             10     23.5    0.7         9     51.0    4.6                      9     27.4    4.0

 500 MG/L           10     22.7    1.2        10     45.9    5.8        90.0         10     23.2    5.9

 1000MG/L           10     23.3    1.0         9     33.8    4.0        66.2          9     10.4    3.3

 2000MG/L           10     23.2    1.5        10     35.0    6.3        68.6         10     11.9    5.2

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