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TDMS Study 97013-93 Pathology Tables

NTP  EXP/TEST: 97013-93                    WATER DISINFECTION MODEL (SODIUM BROMATE)                              PAGE: 1
TEST TYPE: 26-39 WEEKS                          INITIAL AND CURRENT BODY WEIGHT                                   DATE: 12/08/03
ROUTE: DOSED WATER                                                                                                TIME: 14:19:44

                                                         EIS REPORT 03


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  97013H

       CONTRACT NUMBER:  N01-ES-65406

       CAS NUMBER:  7789-38-0

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 97013-93                    WATER DISINFECTION MODEL (SODIUM BROMATE)                              PAGE: 2
TEST TYPE: 26-39 WEEKS                          INITIAL AND CURRENT BODY WEIGHT                                   DATE: 12/08/03
ROUTE: DOSED WATER                                          EISRPT03                                              TIME: 14:19:44
----------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: P53(C57BL/6)-MICE          SEX: FEMALE      WEEK ON DOSE: 43     FIRST DOSE: 09/29/99
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             10     19.6    1.2         9     47.4    8.4                      9     27.6    7.6

 80 MG/L            10     20.0    0.8         9     46.1    7.6        97.2          9     26.0    7.2

 400 MG/L           10     19.7    1.1        10     38.6    7.5        81.4         10     18.9    7.0

 800 MG/L           10     19.8    1.0        10     42.1    6.7        88.8         10     22.3    6.4




----------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: P53(C57BL/6)-MICE          SEX: MALE        WEEK ON DOSE: 43     FIRST DOSE: 09/29/99
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             10     24.8    1.1         9     51.4    3.1                      9     26.7    2.6

 80 MG/L            10     24.6    1.3         8     52.5    3.3       102.1          8     28.1    2.4

 400 MG/L           10     25.2    1.7         8     50.9    4.7        99.0          8     26.1    3.5

 800 MG/L           10     24.7    1.3         9     51.2    4.2        99.6          9     26.4    3.9

                                               -----------------------------------
                                               ---------- END-OF-REPORT ----------
                                               -----------------------------------