National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/11145

TDMS Study 97013-91 Pathology Tables

NTP  EXP/TEST: 97013-91                  WATER DISINFECTION MODEL (DICHLOROACETIC ACID)                           PAGE: 1
TEST TYPE: 26-39 WEEKS                          INITIAL AND CURRENT BODY WEIGHT                                   DATE: 12/05/03
ROUTE: DOSED WATER                                                                                                TIME: 09:17:31

                                                         EIS REPORT 03


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  97013I

       CONTRACT NUMBER:  N01-ES-65406

       CAS NUMBER:  79-43-6

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 97013-91                  WATER DISINFECTION MODEL (DICHLOROACETIC ACID)                           PAGE: 2
TEST TYPE: 26-39 WEEKS                          INITIAL AND CURRENT BODY WEIGHT                                   DATE: 12/05/03
ROUTE: DOSED WATER                                          EISRPT03                                              TIME: 09:17:31
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 SPECIES-STRAIN: TG.AC HEMI-MICE            SEX: FEMALE      WEEK ON DOSE: 41     FIRST DOSE: 01/17/00
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             10     19.2    0.6         7     34.9    4.3                      7     15.7    4.2

 500 MG/L           10     18.9    1.3         9     33.6    6.2        96.2          9     14.6    6.2

 1000MG/L           10     19.0    0.7         7     30.1    3.4        86.2          7     11.1    3.3

 2000MG/L           10     19.1    1.4         8     27.9    5.8        79.9          8      8.9    5.5




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 SPECIES-STRAIN: TG.AC HEMI-MICE            SEX: MALE        WEEK ON DOSE: 41     FIRST DOSE: 01/17/00
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             10     22.1    1.2         9     39.2    6.9                      9     17.2    6.5

 500 MG/L           10     21.6    1.4         9     37.4    5.0        95.4          9     15.8    4.6

 1000MG/L           10     21.5    1.1        10     36.4    4.2        92.8         10     14.9    3.6

 2000MG/L           10     21.7    2.1        10     34.4    2.3        87.7         10     12.7    2.3

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