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Target Organs and Levels of Evidence for TR-002

Carcinogenesis Bioassay of Trichloroethylene (CASRN 79-01-6)

Chemical (Study Title)
CASRN
Peer Review Date Primary Uses Route/Exposure Levels Study Laboratory
Trichloroethylene
79-01-6
NA Degreaser, dry cleaning solvent, manufacture or organic chemicals and pharmaceuticals, heat exchange liquid, diluent in paints and adhesives, caffeine extractant, textile processing, solvent in production of color additives for food, cosmetics, drugs (HSDB 1990). Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products. Gavage
R: 0,549,1097 MM: 0,1169,2339 FM: 0,869,1739 MG/KG/50 PER GROUP
Hazleton, Vienna

Levels of Evidence

Male Rats: Negative
Female Rats: Negative
Male Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)
Female Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)