National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/13353

Target Organs and Levels of Evidence for TR-008

Bioassay of Chlordane for Possible Carcinogenicity (CASRN 57-74-9)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Chlordane (analytical grade)
57-74-9
NAInsecticideDosed-Feed
FR: 0,120.8,241.5 (AVG), MR: 0,203.5,407 (AVG), FM: 0,30.1,63.8 (AVG), MM: 0,29.9,56.2 (AVG) PPM/50 PER GROUP
Gulf South Research Institute

Levels of Evidence

Male Rats: Negative
Female Rats: Negative
Male Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)


NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.