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Target Organs and Levels of Evidence for TR-026

Bioassay of Nitrofen for Possible Carcinogenicity (CASRN 1836-75-5)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Nitrofen
1836-75-5
09/26/1977Pre and post emergence herbicideDosed-Feed
MR: 0,2300,3656 (AVG), FR: 0,1300,2600 (AVG), M: 0,2348,4696 (AVG) PPM/50 PER GROUP
Hazleton, Vienna

Levels of Evidence

Male Rats: Inadequate Study
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Pancreas Acinar Cell: CARCINOMA
Male Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: HEPATOCELLULAR CARCINOMA
  • Vascular System (Liver): HEMANGIOSARCOMA
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: HEPATOCELLULAR CARCINOMA
  • Vascular System (Liver): HEMANGIOSARCOMA