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Target Organs and Levels of Evidence for TR-042

Bioassay of 5-Azacytidine for Possible Carcinogenicity (CASRN 320-67-2)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
5-Azacytidine
320-67-2
11/28/1977Anticancer drug and antibioticIntraperitoneal Injection
R: 0,2.6,5.2, M: 0,2.2,4.4 MG/KG/35 PER GROUP
Southern Research Institute

Levels of Evidence

Male Rats: Inadequate Study
Female Rats: Inadequate Study
Male Mice: Inadequate Study
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Hematopoietic System: (LYMPHOMA OR GRANULOCYTIC SARCOMA)