National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/14756

Target Organs and Levels of Evidence for TR-052

Bioassay of 3-Nitropropionic Acid for Possible Carcinogenicity (CASRN 504-88-1)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
3-Nitropropionic acid
504-88-1
01/18/1978Naturally occurring; food contaminantGavage
MR: 0,.425,.85, FR: 0,.6,1.2, M: 0,.375,.75 MG/50 PER GROUP
Dow

Levels of Evidence

Male Rats: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (NEOPLASTIC NODULE OR CARCINOMA)
  • Pancreas Islet Cell: ADENOMA
Female Rats: Negative
Male Mice: Negative
Female Mice: Negative


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