National Toxicology Program

National Toxicology Program

Target Organs and Levels of Evidence for TR-053

Bioassay of 2-Amino-5-Nitrothiazole for Possible Carcinogenicity (CASRN 121-66-4)

Chemical (Study Title)
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
03/06/1978Antiprotozoal drug in animals (Merck 1989)Dosed-Feed
R: 0,300,600, M: 0,50,100 PPM/50 PER GROUP

Levels of Evidence

Male Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Hematopoietic System: (LYMPHOMA, LEUKEMIA)
Female Rats: Negative
Male Mice: Negative
Female Mice: Negative

NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.