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Target Organs and Levels of Evidence for TR-060

Bioassay of Phenesterin for Possible Carcinogenicity (CASRN 3546-10-9)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Phenesterin
3546-10-9
03/06/1978Anticancer drugGavage
R: 0,5,10, M: 0,15,30 MG/KG/15 PER GROUP
Southern Research Institute

Levels of Evidence

Male Rats: Negative
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Mammary Gland: (ADENOCARCINOMA)
Male Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Lung: (ALVEOLAR/BRONCHIOLAR CARCINOMA)
  • Hematopoietic System: (LYMPHOMA)
  • Heart: (SARCOMA)
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Lung: (ALVEOLAR/BRONCHIOLAR CARCINOMA)
  • Hematopoietic System: (LYMPHOMA)
  • Heart: (SARCOMA)