National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/8216

Target Organs and Levels of Evidence for TR-067

Bioassay of a Mixture of Aspirin, Phenacetin, and Caffeine for Possible Carcinogenicity (CASRN 8003-03-0)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Aspirin, phenacetin, and caffeine
8003-03-0
03/07/1978AnalgesicDosed-Feed
0,0.7,1.4 %/50 PER GROUP
T.S.I. Mason Laboratories, Inc.

Levels of Evidence

Male Rats: Negative
Female Rats: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Urinary Bladder: (TRANSITIONAL CELL CARCINOMA)
  • Kidney Transitional Cell: PAPILLOMA
  • Kidney Tubular Cell: ADENOCARCINOMA
Male Mice: Negative
Female Mice: Negative


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