National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/8222

Target Organs and Levels of Evidence for TR-070

Bioassay of Parathion for Possible Carcinogenicity (CASRN 56-38-2)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Parathion
56-38-2
08/31/1978Pesticide. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.Dosed-Feed
MR: 0,32,63 (AVG), FR: 0,23,45 (AVG), M: 0,80,160 PPM/50 PER GROUP
Gulf South Research Institute

Levels of Evidence

Male Rats: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Adrenal Gland Cortex: ADENOMA OR CARCINOMA
Female Rats: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Adrenal Gland Cortex: ADENOMA OR CARCINOMA
Male Mice: Negative
Female Mice: Negative


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