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Target Organs and Levels of Evidence for TR-074

Bioassay of 1,1,2-Trichloroethane for Possible Carcinogenicity (CASRN 79-00-5)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
1,1,2-Trichloroethane
79-00-5
01/18/1978Intermediate for vinylidene chloride; solvent; in adhesives, teflon, lacquerGavage
R: 0,46,92 (AVG), M: 0,195,390 (AVG) MG/KG/50 PER GROUP
Hazleton, Vienna

Levels of Evidence

Male Rats: Negative
Female Rats: Negative
Male Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)
  • Adrenal Gland Medulla: PHEOCHROMOCYTOMA
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)
  • Adrenal Gland Medulla: PHEOCHROMOCYTOMA