https://ntp.niehs.nih.gov/go/8234

tris(2,3-Dibromopropyl) phosphate: Target Organs and Levels of Evidence for TR-076

Bioassay of Tris (2,3-Dibromopropyl) Phosphate for Possible Carcinogenicity (CASRN 126-72-7)

Chemical (Study Title)
CASRN		 Peer Review Date Route/Exposure Levels Study Laboratory
tris(2,3-Dibromopropyl) phosphate
126-72-7		 03/06/1978 Dosed-Feed
R: 0,50,100, M: 0,500,1000 PPM/55 PER GROUP		 T.S.I. Mason Laboratories, Inc.

Levels of Evidence

Male Rats: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Kidney Tubular Cell: ADENOMA, ADENOMA OR ADENOCARCINOMA
Female Rats: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Kidney Tubular Cell: ADENOMA
Male Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Kidney Tubular Cell: ADENOMA OR ADENOCARCINOMA
  • Forestomach: (SQUAMOUS CELL PAPILLOMA, SQUAMOUS CELL PAPILLOMA OR CARCINOMA)
  • Lung: (ALVEOLAR/BRONCHIOLAR ADENOMA, ALVEOLAR/BRONCHIOLAR CARCINOMA)
Female Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Forestomach: (SQUAMOUS CELL PAPILLOMA, SQUAMOUS CELL CARCINOMA)
  • Liver: (ADENOMA, CARCINOMA)
  • Lung: (ALVEOLAR/BRONCHIOLAR ADENOMA, ALVEOLAR/BRONCHIOLAR ADENOMA OR CARCINOMA)