National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/8236

Target Organs and Levels of Evidence for TR-077

Bioassay of Pyrimethamine for Possible Carcinogenicity (CASRN 58-14-0)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Pyrimethamine
58-14-0
01/18/1978AntimalarialDosed-Feed
R: 0,200,400, M: 0,500,1000 PPM/35 PER GROUP
Southern Research Institute

Levels of Evidence

Male Rats: Negative
Female Rats: Negative
Male Mice: Inadequate Study
Female Mice: Negative


NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.