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Target Organs and Levels of Evidence for TR-077

Bioassay of Pyrimethamine for Possible Carcinogenicity (CASRN 58-14-0)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Pyrimethamine
58-14-0
01/18/1978AntimalarialDosed-Feed
R: 0,200,400, M: 0,500,1000 PPM/35 PER GROUP
Southern Research Institute

Levels of Evidence

Male Rats: Negative
Female Rats: Negative
Male Mice: Inadequate Study
Female Mice: Negative