National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/8238

Target Organs and Levels of Evidence for TR-078

Bioassay of ICRF-159 for Possible Carcinogenicity (CASRN 21416-87-5)

Chemical (Study Title)
CASRN		Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
ICRF-159
21416-87-5		03/07/1978Anticancer drugIntraperitoneal Injection
R: 0,48,96, M: 0,40,80 MG/KG/35 PER GROUP		Southern Research Institute

Levels of Evidence

Male Rats: Negative
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Uterus/Cervix: (ADENOCARCINOMA)
Male Mice: Negative
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Hematopoietic System: (LYMPHOMA)


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Web page last updated on June 27, 2014
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