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Target Organs and Levels of Evidence for TR-078

Bioassay of ICRF-159 for Possible Carcinogenicity (CASRN 21416-87-5)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
ICRF-159
21416-87-5
03/07/1978Anticancer drugIntraperitoneal Injection
R: 0,48,96, M: 0,40,80 MG/KG/35 PER GROUP
Southern Research Institute

Levels of Evidence

Male Rats: Negative
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Uterus/Cervix: (ADENOCARCINOMA)
Male Mice: Negative
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Hematopoietic System: (LYMPHOMA)