National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/8246

Target Organs and Levels of Evidence for TR-083

Bioassay of Daminozide for Possible Carcinogenicity (CASRN 1596-84-5)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Daminozide
1596-84-5
03/07/1978Plant growth retardantDosed-Feed
0,5000,10000 PPM/50 PER GROUP
Litton Bionetics, Inc.

Levels of Evidence

Male Rats: Negative
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Uterus/Cervix: (ADENOCARCINOMA, LEIOMYOSARCOMA)
Male Mice: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)
Female Mice: Negative


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