https://ntp.niehs.nih.gov/go/9593

1,2-Dibromoethane: Target Organs and Levels of Evidence for TR-086

Bioassay of 1,2-Dibromoethane for Possible Carcinogenicity (CASRN 106-93-4)

Chemical (Study Title)
CASRN		 Peer Review Date Route/Exposure Levels Study Laboratory
1,2-Dibromoethane
106-93-4		 04/26/1978 Gavage
MR: 0,38,41 (AVG), FR: 0,37,39 (AVG), M: 0,62,107 MG/KG/50 PER GROUP		 Hazleton, Vienna

Levels of Evidence

Male Rats: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Forestomach: SQUAMOUS CELL CARCINOMA
  • Vascular System (Unspecified): HEMANGIOSARCOMA
Female Rats: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Forestomach: (SQUAMOUS CELL CARCINOMA)
  • Liver: (CARCINOMA)
Male Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Forestomach: (SQUAMOUS CELL CARCINOMA)
  • Lung: (ALVEOLAR/BRONCHIOLAR ADENOMA)
Female Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Forestomach: (SQUAMOUS CELL CARCINOMA)
  • Lung: (ALVEOLAR/BRONCHIOLAR ADENOMA)