Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
https://ntp.niehs.nih.gov/go/13415

Target Organs and Levels of Evidence for TR-118

Bioassay of 5-Nitroacenaphthene for Possible Carcinogenicity (CASRN 602-87-9)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
5-Nitroacenaphthene
602-87-9
06/29/1978Research chemical; in Japan as intermediate for dyes in detergentsDosed-Feed
R: 0,.12,.24, MM: 0,.06,.12 (AVG), FM: 0,.05,.12 (AVG) %/50 PER GROUP
T.S.I. Mason Laboratories, Inc.

Levels of Evidence

Male Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Zymbal Gland: (CARCINOMA)
  • Lung: (ALVEOLAR/BRONCHIOLAR ADENOMA OR CARCINOMA)
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Zymbal Gland: (CARCINOMA)
  • Lung: (ALVEOLAR/BRONCHIOLAR ADENOMA OR CARCINOMA)
  • Mammary Gland: (ADENOCARCINOMA)
  • Clitoral Gland: (CARCINOMA)
Male Mice: Negative
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)
  • Ovary: (TUBULAR CELL ADENOMA OR GRANULOSA CELL TUMOR OR LUTEOMA)