National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/13435

Target Organs and Levels of Evidence for TR-129

Bioassay of Trimethylthiourea for Possible Carcinogenicity (CASRN 2489-77-2)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Trimethylthiourea
2489-77-2
08/31/1978Vulcanization; adhesives; polyethylene film; chemical intermediate; useful in a wide variety of industrial applicationsDosed-Feed
R: 0,250,500, M: 0,500,1000 PPM/50 PER GROUP
Litton Bionetics, Inc.

Levels of Evidence

Male Rats: Negative
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Thyroid Gland Follicular Cell: CARCINOMA
Male Mice: Negative
Female Mice: Negative


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