National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/13445

Target Organs and Levels of Evidence for TR-134

Bioassay of C.I. Vat Yellow 4 for Possible Carcinogenicity (CASRN 128-66-5)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
C.I. Vat yellow 4
128-66-5
08/31/1978Dye for cellulose fibers and synthetics, wool, silk; pigment for paper; military smoke dyeDosed-Feed
R: 0,3500,7000, MM: 0,25000,50000, FM: 0,12500,25000 PPM/50 PER GROUP
Frederick Cancer Research Facility

Levels of Evidence

Male Rats: Negative
Female Rats: Negative
Male Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Hematopoietic System: (LYMPHOMA)
Female Mice: Negative


NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.